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Illumina Body Map 2 (GSE30611)
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Results for ZNF652
Z-value: 1.27
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Transcription factors associated with ZNF652
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF652 | hg38_v1_chr17_-_49362206_49362279 | 0.26 | 1.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF652
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.7 | GO:0051621 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.4 | 5.4 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 5.1 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.4 | 4.3 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 1.1 | 4.2 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.2 | 4.1 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.2 | 4.1 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 3.7 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 1.1 | 3.4 | GO:0006147 | guanine catabolic process(GO:0006147) |
| 0.0 | 3.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 7.9 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 7.4 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 5.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 5.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 5.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 1.1 | 4.3 | GO:0071757 | hexameric IgM immunoglobulin complex(GO:0071757) |
| 0.1 | 4.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 4.2 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 2.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.7 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.4 | 5.4 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 5.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 5.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 4.9 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.5 | 4.4 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.6 | 4.3 | GO:0019862 | IgA binding(GO:0019862) |
| 0.4 | 4.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 1.1 | 3.4 | GO:0008892 | guanine deaminase activity(GO:0008892) |
| 0.0 | 3.2 | GO:0030507 | spectrin binding(GO:0030507) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 7.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 4.2 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 4.0 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 3.8 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 3.7 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 2.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 1.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.7 | PID IGF1 PATHWAY | IGF1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 3.8 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.2 | 3.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 3.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 2.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.0 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 1.9 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.9 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 1.8 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.7 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |