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Illumina Body Map 2 (GSE30611)

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Results for ZSCAN4

Z-value: 0.90

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Transcription factors associated with ZSCAN4

Gene Symbol Gene ID Gene Info
ENSG00000180532.11 zinc finger and SCAN domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZSCAN4hg38_v1_chr19_+_57670242_57670242-0.048.2e-01Click!

Activity profile of ZSCAN4 motif

Sorted Z-values of ZSCAN4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_2796404 3.38 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chrX_-_20116871 2.76 ENST00000379651.7
ENST00000443379.7
ENST00000379643.10
MAP7 domain containing 2
chr3_+_111674654 2.53 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
phosphatidylinositol specific phospholipase C X domain containing 2
chr3_-_116445458 2.48 ENST00000490035.7
limbic system associated membrane protein
chr4_-_167234426 2.31 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr11_-_125592448 2.26 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr3_-_116444983 2.23 ENST00000333617.8
limbic system associated membrane protein
chr7_-_29969232 2.15 ENST00000409497.5
secernin 1
chr4_-_167234579 2.11 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr20_+_10218948 1.95 ENST00000430336.1
synaptosome associated protein 25
chr12_+_40692413 1.94 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr3_-_58587033 1.80 ENST00000447756.2
family with sequence similarity 107 member A
chr1_-_177164673 1.70 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr11_-_75351609 1.70 ENST00000420843.7
arrestin beta 1
chr12_-_16609869 1.69 ENST00000534946.5
LIM domain only 3
chr8_+_26390362 1.68 ENST00000518611.5
BCL2 interacting protein 3 like
chr11_-_125496122 1.62 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
fasciculation and elongation protein zeta 1
chr1_-_184037695 1.57 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chrX_-_20116595 1.54 ENST00000452324.3
MAP7 domain containing 2
chr12_+_120650492 1.54 ENST00000351200.6
calcium binding protein 1
chr19_+_30372364 1.48 ENST00000355537.4
zinc finger protein 536
chr14_+_64704102 1.47 ENST00000555982.5
pleckstrin homology and RhoGEF domain containing G3
chr11_+_65833944 1.47 ENST00000308342.7
sorting nexin 32
chr1_+_226548747 1.46 ENST00000366788.8
ENST00000366789.5
stum, mechanosensory transduction mediator homolog
chr6_-_152563271 1.41 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr1_+_159171607 1.41 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
cell adhesion molecule 3
chr4_-_167234266 1.34 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr19_+_735026 1.34 ENST00000592155.5
ENST00000590161.2
paralemmin
chr7_+_121873317 1.33 ENST00000651863.1
ENST00000652298.1
ENST00000449182.1
protein tyrosine phosphatase receptor type Z1
chr1_-_161631152 1.31 ENST00000421702.3
ENST00000650385.1
Fc fragment of IgG receptor IIIb
chr16_+_15643267 1.31 ENST00000396355.5
nudE neurodevelopment protein 1
chr1_-_161631032 1.30 ENST00000534776.1
ENST00000613418.4
ENST00000614870.4
Fc fragment of IgG receptor IIIb
chr8_-_133102477 1.29 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr11_-_75351686 1.18 ENST00000360025.7
arrestin beta 1
chr10_+_43437105 1.16 ENST00000456416.6
ENST00000437590.3
ENST00000451167.2
zinc finger protein 487
chr19_-_35135180 1.13 ENST00000392225.7
leucine rich repeat LGI family member 4
chr1_+_2104710 1.09 ENST00000482686.5
ENST00000486681.5
protein kinase C zeta
chrX_+_1268807 1.08 ENST00000381524.8
ENST00000381529.9
ENST00000412290.6
colony stimulating factor 2 receptor subunit alpha
chr19_-_39320839 1.08 ENST00000248668.5
leucine rich repeat and fibronectin type III domain containing 1
chr9_+_122375286 1.07 ENST00000373698.7
prostaglandin-endoperoxide synthase 1
chr10_+_18260715 1.06 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr19_-_9538590 1.04 ENST00000593003.5
zinc finger protein 426
chr2_+_10368645 1.04 ENST00000613496.4
hippocalcin like 1
chr3_+_50246888 1.03 ENST00000451956.1
G protein subunit alpha i2
chr11_-_18791563 1.02 ENST00000396168.1
protein tyrosine phosphatase non-receptor type 5
chr6_-_41941728 1.01 ENST00000414200.6
cyclin D3
chr12_-_16610037 1.00 ENST00000540590.1
LIM domain only 3
chr19_-_38224215 0.99 ENST00000355526.10
ENST00000420980.7
ENST00000614244.4
double PHD fingers 1
chrX_+_1268828 0.99 ENST00000432318.8
ENST00000381509.8
ENST00000494969.7
ENST00000355805.7
ENST00000355432.8
colony stimulating factor 2 receptor subunit alpha
chr13_-_114132580 0.98 ENST00000334062.8
RAS p21 protein activator 3
chr17_+_32021005 0.93 ENST00000327564.11
ENST00000584368.5
ENST00000394713.7
ENST00000341671.11
leucine rich repeat containing 37B
chr2_-_212124901 0.93 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr11_+_61950343 0.92 ENST00000378043.9
bestrophin 1
chr18_+_34593312 0.92 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr6_-_41941795 0.91 ENST00000372991.9
cyclin D3
chr11_+_61950063 0.89 ENST00000534553.5
bestrophin 1
chr4_-_167234552 0.89 ENST00000512648.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr3_+_184276007 0.88 ENST00000359140.8
ENST00000404464.8
ENST00000357474.9
endothelin converting enzyme 2
chr13_+_111114550 0.88 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr6_-_41941507 0.87 ENST00000372987.8
cyclin D3
chr1_-_161549793 0.83 ENST00000443193.6
Fc fragment of IgG receptor IIIa
chr9_+_121286586 0.83 ENST00000545652.6
gelsolin
chr9_+_137139139 0.81 ENST00000371561.8
glutamate ionotropic receptor NMDA type subunit 1
chr14_-_93788475 0.79 ENST00000393140.6
proline rich membrane anchor 1
chr1_-_161549892 0.78 ENST00000426740.7
Fc fragment of IgG receptor IIIa
chr11_-_1598294 0.78 ENST00000412090.2
keratin associated protein 5-2
chr2_-_223945354 0.77 ENST00000429915.1
WD repeat and FYVE domain containing 1
chr8_-_133102623 0.77 ENST00000524345.5
Src like adaptor
chr19_-_40056156 0.75 ENST00000598845.5
ENST00000593605.1
ENST00000221355.10
ENST00000434248.6
zinc finger protein 780B
chr5_+_137889437 0.75 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr6_-_152563349 0.74 ENST00000673281.1
spectrin repeat containing nuclear envelope protein 1
chr2_-_174598206 0.73 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr11_-_41459592 0.72 ENST00000528697.6
ENST00000530763.5
leucine rich repeat containing 4C
chr19_-_3801791 0.72 ENST00000590849.1
ENST00000395045.6
megakaryocyte-associated tyrosine kinase
chr19_-_42132465 0.71 ENST00000529067.5
ENST00000529952.5
ENST00000342301.8
ENST00000389341.9
POU class 2 homeobox 2
chrX_+_1268786 0.67 ENST00000501036.7
ENST00000417535.7
colony stimulating factor 2 receptor subunit alpha
chr2_-_223945322 0.65 ENST00000233055.9
WD repeat and FYVE domain containing 1
chr17_-_48722510 0.64 ENST00000290294.5
PRAC1 small nuclear protein
chr5_+_153490727 0.64 ENST00000340592.9
glutamate ionotropic receptor AMPA type subunit 1
chr6_+_29827817 0.60 ENST00000360323.11
ENST00000376818.7
ENST00000376815.3
major histocompatibility complex, class I, G
chr2_+_172860038 0.59 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr10_+_18261080 0.59 ENST00000377319.8
ENST00000377331.8
calcium voltage-gated channel auxiliary subunit beta 2
chr12_-_96400365 0.58 ENST00000261211.8
ENST00000543119.6
cyclin dependent kinase 17
chr13_-_79406175 0.57 ENST00000438724.5
ENST00000622611.4
ENST00000438737.3
RNA binding motif protein 26
chr8_-_133102643 0.57 ENST00000519341.5
Src like adaptor
chr19_-_42132391 0.56 ENST00000528894.8
ENST00000560804.6
ENST00000560558.5
ENST00000560398.5
ENST00000526816.6
ENST00000625670.2
POU class 2 homeobox 2
chrX_-_6227180 0.56 ENST00000381093.6
neuroligin 4 X-linked
chr12_+_6924449 0.56 ENST00000356654.8
atrophin 1
chr12_-_6631632 0.55 ENST00000431922.1
lysophosphatidic acid receptor 5
chr1_-_154608140 0.54 ENST00000529168.2
ENST00000368474.9
ENST00000680305.1
ENST00000648231.2
adenosine deaminase RNA specific
chr18_+_75210789 0.53 ENST00000580243.3
teashirt zinc finger homeobox 1
chr19_+_44259875 0.53 ENST00000592581.5
ENST00000590668.5
ENST00000683810.1
zinc finger protein 233
chr8_+_84182777 0.53 ENST00000522613.5
RALY RNA binding protein like
chrX_-_63351308 0.53 ENST00000374884.3
spindlin family member 4
chr1_+_35869750 0.50 ENST00000373206.5
argonaute RISC component 1
chr8_-_133102874 0.49 ENST00000395352.7
Src like adaptor
chr19_+_47332167 0.48 ENST00000595464.3
complement component 5a receptor 2
chr7_+_64045420 0.48 ENST00000647787.1
ENST00000456806.3
novel transcript
zinc finger protein 727
chr17_+_41265339 0.47 ENST00000391355.1
keratin associated protein 9-6
chr4_+_15778320 0.47 ENST00000226279.8
CD38 molecule
chr19_+_44212525 0.47 ENST00000391961.6
ENST00000621083.4
ENST00000313040.12
ENST00000586228.5
ENST00000588219.5
ENST00000589707.5
ENST00000588394.5
ENST00000589005.5
zinc finger protein 227
chr8_+_38974212 0.47 ENST00000302495.5
HtrA serine peptidase 4
chr13_-_52159559 0.46 ENST00000620675.4
ENST00000610828.5
NIMA related kinase 3
chr15_+_78340344 0.46 ENST00000299529.7
cellular retinoic acid binding protein 1
chr4_+_73853290 0.46 ENST00000226524.4
platelet factor 4 variant 1
chr17_+_4715438 0.45 ENST00000571206.1
arrestin beta 2
chr9_-_89405926 0.42 ENST00000433650.5
semaphorin 4D
chr8_+_43056409 0.42 ENST00000525699.5
ENST00000529687.5
farnesyltransferase, CAAX box, alpha
chr18_+_34593392 0.42 ENST00000684377.1
dystrobrevin alpha
chr7_+_142720652 0.41 ENST00000390400.2
T cell receptor beta variable 28
chr19_+_56507800 0.41 ENST00000591537.5
ENST00000308031.10
zinc finger protein 471
chr3_-_53255990 0.41 ENST00000423525.6
transketolase
chr11_-_33753394 0.41 ENST00000532057.5
ENST00000531080.5
F-box protein 3
chr12_-_84911178 0.40 ENST00000681688.1
solute carrier family 6 member 15
chr6_-_15548360 0.40 ENST00000509674.1
dystrobrevin binding protein 1
chr8_+_84183534 0.40 ENST00000518566.5
RALY RNA binding protein like
chr18_+_58864866 0.40 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr19_-_40090860 0.39 ENST00000599972.1
ENST00000450241.6
ENST00000595687.6
ENST00000340963.9
zinc finger protein 780A
chr9_-_20621835 0.39 ENST00000630269.2
MLLT3 super elongation complex subunit
chr12_+_54549586 0.39 ENST00000243052.8
phosphodiesterase 1B
chr2_+_240625237 0.39 ENST00000407714.1
G protein-coupled receptor 35
chr11_+_56027654 0.39 ENST00000641320.1
olfactory receptor family 5 subfamily AS member 1
chr7_-_78771265 0.38 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_53256009 0.36 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chr1_-_153945225 0.34 ENST00000368646.6
DENN domain containing 4B
chr17_-_58328756 0.34 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr13_-_52159529 0.34 ENST00000618534.4
ENST00000550841.1
NIMA related kinase 3
chr12_+_10010627 0.33 ENST00000338896.11
ENST00000396502.5
C-type lectin domain family 12 member B
chr16_-_55875299 0.33 ENST00000520435.2
carboxylesterase 5A
chr19_+_571274 0.33 ENST00000545507.6
ENST00000346916.9
basigin (Ok blood group)
chr1_-_111488795 0.32 ENST00000472933.2
transmembrane and immunoglobulin domain containing 3
chr7_-_78770859 0.32 ENST00000636717.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_102808057 0.32 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr7_-_149126306 0.32 ENST00000483014.1
ENST00000378061.7
zinc finger protein 425
chr12_-_10998304 0.31 ENST00000538986.2
taste 2 receptor member 20
chr19_+_44259903 0.30 ENST00000588489.5
ENST00000391958.6
zinc finger protein 233
chr19_-_40090921 0.30 ENST00000595508.1
ENST00000414720.6
ENST00000455521.5
ENST00000595773.5
ENST00000683561.1
novel transcript
zinc finger protein 780A
chr6_-_39725387 0.30 ENST00000287152.12
kinesin family member 6
chr8_+_106580970 0.29 ENST00000517686.5
oxidation resistance 1
chr3_-_177196402 0.29 ENST00000437738.5
ENST00000424913.5
ENST00000443315.5
TBL1X receptor 1
chr16_-_55875358 0.27 ENST00000319165.13
ENST00000290567.14
carboxylesterase 5A
chr1_+_169367934 0.26 ENST00000367807.7
ENST00000329281.6
ENST00000420531.1
basic leucine zipper nuclear factor 1
chr7_-_78771058 0.25 ENST00000628781.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_102760976 0.23 ENST00000644159.1
ENST00000642252.1
mannosidase beta
chr15_+_75258599 0.23 ENST00000300576.5
golgin A6 family member C
chr1_-_153312919 0.23 ENST00000683862.1
peptidoglycan recognition protein 3
chr3_+_130850585 0.23 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr4_-_102760914 0.22 ENST00000505239.1
ENST00000647097.2
mannosidase beta
chr6_-_33580229 0.22 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr13_-_52159844 0.22 ENST00000611833.4
NIMA related kinase 3
chr15_-_74082550 0.22 ENST00000290438.3
golgin A6 family member A
chr15_+_67125707 0.21 ENST00000540846.6
SMAD family member 3
chr11_+_61950370 0.20 ENST00000449131.6
bestrophin 1
chr7_-_78771108 0.20 ENST00000626691.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_111879482 0.20 ENST00000260276.8
ENST00000530214.5
ENST00000530799.5
chromosome 11 open reading frame 1
chr6_-_145735964 0.20 ENST00000640980.1
ENST00000639423.1
ENST00000611340.5
EPM2A glucan phosphatase, laforin
chr20_-_21514046 0.20 ENST00000377142.5
NK2 homeobox 2
chr15_-_37100523 0.20 ENST00000424352.6
ENST00000561208.6
Meis homeobox 2
chr22_+_44752552 0.19 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr1_+_94418467 0.19 ENST00000315713.5
ATP binding cassette subfamily D member 3
chr1_+_61203496 0.18 ENST00000663597.1
nuclear factor I A
chr11_-_128942849 0.18 ENST00000531399.6
ENST00000458238.6
tumor protein p53 regulated apoptosis inducing protein 1
chr2_+_127535746 0.18 ENST00000428314.5
ENST00000409816.7
myosin VIIB
chr18_-_23662868 0.18 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr17_-_35432490 0.18 ENST00000304905.10
schlafen family member 12
chr19_-_44529525 0.17 ENST00000620096.4
ENST00000614577.4
ENST00000611497.4
ENST00000614924.5
CEA cell adhesion molecule 20
chr1_-_7940825 0.17 ENST00000377507.8
TNF receptor superfamily member 9
chr19_-_10420121 0.17 ENST00000593124.1
cell division cycle 37, HSP90 cochaperone
chr1_+_15438435 0.16 ENST00000375943.6
ENST00000375949.5
chymotrypsin C
chr19_+_48695952 0.15 ENST00000522966.2
ENST00000425340.3
ENST00000391876.5
fucosyltransferase 2
chr10_-_48605032 0.14 ENST00000249601.9
Rho GTPase activating protein 22
chr14_+_52707192 0.13 ENST00000445930.7
ENST00000555339.5
ENST00000556813.1
proteasome 26S subunit, ATPase 6
chr6_-_30686624 0.13 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr9_-_122228845 0.12 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr12_+_121804689 0.12 ENST00000619791.1
ENST00000267197.9
SET domain containing 1B, histone lysine methyltransferase
chr1_+_8945858 0.12 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr14_+_52707178 0.12 ENST00000612399.4
proteasome 26S subunit, ATPase 6
chr5_-_83673544 0.12 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr1_+_209756101 0.11 ENST00000479796.5
TRAF3 interacting protein 3
chr16_+_6019663 0.11 ENST00000422070.8
RNA binding fox-1 homolog 1
chr11_-_129947461 0.10 ENST00000526082.5
ENST00000304538.10
PR/SET domain 10
chr19_+_51127030 0.10 ENST00000599948.1
sialic acid binding Ig like lectin 9
chr7_-_99466148 0.10 ENST00000394186.3
ENST00000359832.8
ENST00000449683.5
ENST00000292475.8
ENST00000488775.5
ENST00000523680.1
ENST00000430982.1
ENST00000413834.5
ATP synthase membrane subunit f
pentatricopeptide repeat domain 1
ATP5MF-PTCD1 readthrough
chr11_+_10455292 0.09 ENST00000396553.6
adenosine monophosphate deaminase 3
chr22_+_44031345 0.09 ENST00000444029.5
parvin beta
chr10_+_38010617 0.08 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr1_+_209756032 0.08 ENST00000400959.7
ENST00000367025.8
TRAF3 interacting protein 3
chr7_-_16420623 0.08 ENST00000676325.1
CDP-L-ribitol pyrophosphorylase A
chr7_-_10940123 0.08 ENST00000339600.6
NDUFA4 mitochondrial complex associated
chr8_-_23854796 0.08 ENST00000290271.7
stanniocalcin 1
chr12_+_133037350 0.08 ENST00000438628.6
zinc finger protein 84
chr9_-_20622479 0.07 ENST00000380338.9
MLLT3 super elongation complex subunit
chr17_-_19745602 0.06 ENST00000444455.5
ENST00000439102.6
aldehyde dehydrogenase 3 family member A1
chr3_-_195811857 0.06 ENST00000349607.8
ENST00000346145.8
mucin 4, cell surface associated
chrX_+_17375194 0.06 ENST00000676302.1
NHS actin remodeling regulator
chr12_-_47771029 0.06 ENST00000549151.5
ENST00000548919.5
Rap guanine nucleotide exchange factor 3
chr1_-_25430147 0.05 ENST00000349320.7
Rh blood group CcEe antigens
chr1_+_169368175 0.05 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chr2_+_149118169 0.05 ENST00000450639.5
LY6/PLAUR domain containing 6B
chr10_+_113679159 0.04 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7

Network of associatons between targets according to the STRING database.

First level regulatory network of ZSCAN4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 1.3 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.3 3.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 0.8 GO:0008355 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.3 5.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 0.8 GO:0005999 xylulose biosynthetic process(GO:0005999)
0.2 2.7 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 3.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.9 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 2.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2 0.8 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.5 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.2 4.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 1.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 2.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 1.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 1.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.3 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 1.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.2 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 2.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.4 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.4 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0015820 leucine transport(GO:0015820)
0.0 3.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.5 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.8 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 2.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.9 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 1.1 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 3.4 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 2.3 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 1.6 GO:0021549 cerebellum development(GO:0021549)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.5 GO:0042308 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 1.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.4 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.6 GO:0044308 axonal spine(GO:0044308)
0.1 2.9 GO:0031143 pseudopodium(GO:0031143)
0.1 2.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0090651 apical cytoplasm(GO:0090651)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0000322 storage vacuole(GO:0000322)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 1.6 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 6.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 4.2 GO:0019864 IgG binding(GO:0019864)
0.2 1.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 0.4 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.2 1.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.5 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.2 0.8 GO:0004802 transketolase activity(GO:0004802)
0.1 0.4 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 1.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 3.8 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 3.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 2.2 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.8 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 3.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 2.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 2.9 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds