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avrg: Illumina Body Map 2 (GSE30611)

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Results for AAUCUCA

Z-value: 0.50

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miRNA associated with seed AAUCUCA

NamemiRBASE accession
hsa-miR-216a-5p
MIMAT0000273

Activity profile of AAUCUCA motif

Sorted Z-values of AAUCUCA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_49950733 2.34 ENST00000199280.4
ENST00000550862.1
AQP2
aquaporin 2
chr11_-_32430811 1.05 ENST00000379079.8
ENST00000530998.5
WT1
WT1 transcription factor
chr1_-_67054100 0.68 ENST00000235345.6
SLC35D1
solute carrier family 35 member D1
chr17_+_14301069 0.61 ENST00000360954.3
HS3ST3B1
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr5_+_123089223 0.46 ENST00000407847.5
PRDM6
PR/SET domain 6
chr1_+_63322558 0.42 ENST00000371116.4
FOXD3
forkhead box D3
chr4_+_98995709 0.41 ENST00000296411.11
ENST00000625963.1
METAP1
methionyl aminopeptidase 1
chr2_-_241272812 0.36 ENST00000427007.5
ENST00000458564.5
ENST00000452065.5
ENST00000427183.6
ENST00000426343.5
ENST00000422080.5
ENST00000449504.5
ENST00000449864.5
ENST00000391975.5
HDLBP
high density lipoprotein binding protein
chr7_-_140176970 0.32 ENST00000397560.7
KDM7A
lysine demethylase 7A
chr4_-_112516176 0.26 ENST00000313341.4
NEUROG2
neurogenin 2
chrX_-_20266834 0.25 ENST00000379565.9
RPS6KA3
ribosomal protein S6 kinase A3
chr17_+_66302606 0.22 ENST00000413366.8
PRKCA
protein kinase C alpha
chr9_-_20622479 0.21 ENST00000380338.9
MLLT3
MLLT3 super elongation complex subunit
chr6_+_42782020 0.14 ENST00000314073.9
BICRAL
BRD4 interacting chromatin remodeling complex associated protein like
chr15_+_40440889 0.14 ENST00000416165.6
BAHD1
bromo adjacent homology domain containing 1
chr5_-_178627001 0.13 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CLK4
CDC like kinase 4
chr1_-_67430412 0.12 ENST00000370994.8
SERBP1
SERPINE1 mRNA binding protein 1
chr13_-_45341086 0.12 ENST00000309246.9
ENST00000379060.8
ENST00000379055.5
ENST00000527226.2
ENST00000530705.6
ENST00000379056.5
ENST00000616577.4
TPT1
tumor protein, translationally-controlled 1
chr17_+_55264952 0.12 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr12_-_56636318 0.10 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr18_+_62187247 0.09 ENST00000644646.2
ENST00000256858.10
ENST00000398130.6
RELCH
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
chr11_+_112074287 0.07 ENST00000532163.5
ENST00000280352.13
ENST00000393047.8
ENST00000526879.5
ENST00000525785.5
NKAPD1
NKAP domain containing 1
chr17_-_4263847 0.06 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr20_-_543770 0.05 ENST00000460062.7
ENST00000645187.1
ENST00000647348.1
ENST00000217244.9
ENST00000349736.10
CSNK2A1
casein kinase 2 alpha 1
chr3_+_126983035 0.01 ENST00000393409.3
PLXNA1
plexin A1
chr11_+_74748831 0.01 ENST00000299563.5
RNF169
ring finger protein 169
chrX_+_23334841 0.00 ENST00000379361.5
PTCHD1
patched domain containing 1
chr5_+_149730260 0.00 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARGC1B
PPARG coactivator 1 beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0071288 cellular response to water deprivation(GO:0042631) cellular response to mercury ion(GO:0071288)
0.3 1.1 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 1.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis