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avrg: Illumina Body Map 2 (GSE30611)
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Results for AGCACCA
Z-value: 2.40
Motif logo
miRNA associated with seed AGCACCA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-29a-3p
|
MIMAT0000086 |
|
hsa-miR-29b-3p
|
MIMAT0000100 |
|
hsa-miR-29c-3p
|
MIMAT0000681 |
Activity profile of AGCACCA motif
Sorted Z-values of AGCACCA motif
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 12.1 | GO:0044691 | tooth eruption(GO:0044691) |
| 2.5 | 9.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.4 | 6.8 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 1.1 | 4.6 | GO:0018277 | protein deamination(GO:0018277) |
| 1.1 | 3.4 | GO:0060981 | cell migration involved in coronary angiogenesis(GO:0060981) |
| 0.9 | 8.3 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.9 | 6.4 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.8 | 3.9 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.8 | 6.9 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.7 | 2.2 | GO:0051041 | positive regulation of calcium-independent cell-cell adhesion(GO:0051041) |
| 0.7 | 6.0 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.6 | 3.1 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.6 | 2.3 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.5 | 3.5 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 0.5 | 3.0 | GO:0021827 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925) |
| 0.5 | 7.3 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.5 | 5.3 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.5 | 2.4 | GO:1904075 | regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) |
| 0.4 | 5.3 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.4 | 0.4 | GO:1904761 | negative regulation of myofibroblast differentiation(GO:1904761) |
| 0.4 | 3.2 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.4 | 1.2 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.4 | 1.2 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.3 | 1.0 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 0.3 | 1.3 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) |
| 0.3 | 2.3 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.3 | 4.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 1.5 | GO:0045074 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 0.3 | 3.9 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) |
| 0.3 | 2.2 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.3 | 0.8 | GO:0044335 | canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) |
| 0.2 | 5.0 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.2 | 2.7 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.2 | 2.6 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.2 | 0.7 | GO:1990709 | presynaptic active zone organization(GO:1990709) |
| 0.2 | 23.1 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.2 | 0.6 | GO:0090325 | regulation of locomotion involved in locomotory behavior(GO:0090325) |
| 0.2 | 1.7 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.2 | 0.6 | GO:1903572 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.2 | 0.8 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.2 | 0.8 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.2 | 1.6 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
| 0.2 | 2.0 | GO:2000823 | regulation of androgen receptor activity(GO:2000823) |
| 0.2 | 0.8 | GO:1901073 | N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073) |
| 0.2 | 0.9 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.2 | 0.9 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.2 | 0.5 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.2 | 0.5 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.2 | 0.8 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.2 | 1.8 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 1.3 | GO:0061743 | motor learning(GO:0061743) |
| 0.2 | 0.5 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.2 | 0.8 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.1 | 1.9 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.1 | 3.9 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.1 | 0.7 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.1 | 2.4 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.1 | 1.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 1.4 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.1 | 1.2 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 4.9 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.1 | 0.8 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.1 | 0.6 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.1 | 1.3 | GO:1901475 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 1.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.5 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 0.4 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
| 0.1 | 0.4 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 2.4 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.1 | 0.6 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.1 | 3.5 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 0.6 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 0.9 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.1 | 1.1 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.1 | 5.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.1 | 1.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 1.5 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 1.0 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 0.1 | 1.4 | GO:0071711 | basement membrane organization(GO:0071711) |
| 0.1 | 0.5 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
| 0.1 | 2.2 | GO:0038065 | collagen-activated signaling pathway(GO:0038065) |
| 0.1 | 2.1 | GO:0045636 | positive regulation of melanocyte differentiation(GO:0045636) |
| 0.1 | 2.4 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 1.0 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.1 | 0.5 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
| 0.1 | 1.4 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 2.8 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.1 | 1.4 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.7 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.1 | 0.2 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.1 | 0.1 | GO:0071338 | submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
| 0.1 | 0.3 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 1.1 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 2.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.5 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.1 | 0.5 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.1 | 0.8 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.1 | 0.8 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.3 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 1.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.1 | 0.7 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.1 | 0.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 2.1 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.1 | 0.3 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.1 | 0.2 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 0.1 | 0.2 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
| 0.1 | 0.3 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.1 | 0.6 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.3 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.1 | 0.3 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.1 | 0.2 | GO:1900276 | regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737) |
| 0.1 | 7.0 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.4 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.0 | 0.4 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.0 | 0.1 | GO:2000797 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 0.0 | 2.1 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 0.4 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
| 0.0 | 0.9 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.0 | 0.3 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.0 | 0.1 | GO:0060921 | sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931) |
| 0.0 | 1.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.0 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.0 | 0.2 | GO:1903912 | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912) |
| 0.0 | 0.6 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.0 | 0.8 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.4 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.0 | 0.5 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 1.1 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 1.0 | GO:0051923 | sulfation(GO:0051923) |
| 0.0 | 2.7 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.6 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 1.1 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 2.7 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.8 | GO:1902514 | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) |
| 0.0 | 0.8 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.0 | 0.2 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.0 | 0.2 | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
| 0.0 | 0.2 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 3.6 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.1 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.6 | GO:0030949 | positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949) |
| 0.0 | 1.6 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.0 | 1.0 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.0 | 0.5 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 0.5 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 0.6 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.0 | 0.3 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 0.1 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.0 | 0.2 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.0 | 0.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.1 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.0 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 1.2 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 0.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.0 | 0.6 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 2.4 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.0 | 0.2 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.0 | 1.1 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.1 | GO:1904828 | regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828) |
| 0.0 | 0.1 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.0 | 0.7 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 0.7 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.0 | 1.8 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.0 | 0.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 0.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.5 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.0 | 1.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.1 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.0 | 0.2 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.0 | 0.1 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.0 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.0 | 0.6 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 2.7 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 0.2 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.0 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.0 | 0.1 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 0.0 | 2.6 | GO:0060071 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) |
| 0.0 | 0.1 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.0 | 0.2 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
| 0.0 | 0.3 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.1 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.1 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 3.3 | GO:0042594 | response to starvation(GO:0042594) |
| 0.0 | 0.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.2 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.1 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.0 | 0.1 | GO:0034086 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 15.7 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 3.2 | 12.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.3 | 3.9 | GO:0043260 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 0.9 | 15.8 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.9 | 9.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.7 | 3.6 | GO:0034681 | integrin alpha11-beta1 complex(GO:0034681) |
| 0.5 | 4.8 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.3 | 1.6 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.3 | 6.5 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 3.4 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.2 | 2.4 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.2 | 1.1 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.2 | 1.1 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.2 | 0.9 | GO:0034753 | nuclear aryl hydrocarbon receptor complex(GO:0034753) |
| 0.2 | 1.1 | GO:0031523 | Myb complex(GO:0031523) |
| 0.2 | 0.8 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.1 | 1.9 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 2.1 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.1 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 3.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 18.9 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 0.9 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 3.5 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.1 | 1.0 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.1 | 0.2 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 1.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.2 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.1 | 0.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 5.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 1.3 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.5 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 0.2 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
| 0.1 | 33.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 2.3 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 2.0 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 0.2 | GO:0039714 | viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517) |
| 0.1 | 0.6 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.5 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 0.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 1.1 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.7 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 1.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 3.2 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.8 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.5 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 3.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 6.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 1.1 | GO:0043218 | compact myelin(GO:0043218) |
| 0.0 | 11.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.1 | GO:0032116 | SMC loading complex(GO:0032116) |
| 0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.0 | 0.2 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 0.6 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.0 | 3.4 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.8 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 1.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.2 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.2 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 0.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.0 | 0.6 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 0.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 0.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.2 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.0 | 0.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 10.4 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.0 | GO:0033290 | eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207) |
| 0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.3 | GO:0016580 | Sin3 complex(GO:0016580) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 37.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 1.3 | 5.3 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 1.0 | 4.9 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.9 | 8.7 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.7 | 2.2 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.7 | 2.2 | GO:0031737 | CX3C chemokine receptor binding(GO:0031737) |
| 0.5 | 3.2 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.5 | 2.0 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.5 | 1.5 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.5 | 2.4 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.4 | 3.6 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.4 | 2.8 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.4 | 1.2 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.4 | 2.3 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.4 | 3.6 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.3 | 1.3 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.3 | 1.2 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.3 | 0.8 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.2 | 3.0 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 29.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 2.6 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.2 | 0.7 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 0.2 | 1.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.2 | 1.5 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.2 | 0.6 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.2 | 1.0 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.2 | 0.8 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.2 | 1.0 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.2 | 3.9 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.2 | 1.9 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.2 | 2.9 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.2 | 1.6 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.2 | 3.6 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.2 | 0.8 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.2 | 3.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 1.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.2 | 1.4 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 1.0 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 1.7 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 1.8 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.8 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.1 | 2.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 0.6 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 0.5 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.1 | 0.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 0.5 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 0.5 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.1 | 18.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.5 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
| 0.1 | 1.0 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 1.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 1.6 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.1 | 0.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 0.7 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 0.4 | GO:0004096 | catalase activity(GO:0004096) |
| 0.1 | 1.3 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.4 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 0.2 | GO:0090631 | pre-miRNA transporter activity(GO:0090631) |
| 0.1 | 0.8 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 0.2 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.0 | 9.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 1.0 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.0 | 7.5 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.6 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.8 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 0.2 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.0 | 0.6 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.1 | GO:0032427 | GBD domain binding(GO:0032427) apolipoprotein A-I receptor binding(GO:0034191) |
| 0.0 | 0.4 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 0.0 | 0.2 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 1.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.1 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.0 | 6.3 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 0.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.2 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 0.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.8 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.1 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.0 | 1.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 3.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 1.9 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 1.0 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.3 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.3 | GO:0046935 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 0.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 2.5 | GO:0030414 | peptidase inhibitor activity(GO:0030414) |
| 0.0 | 1.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.5 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.5 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.6 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.0 | 0.2 | GO:0016433 | rRNA (adenine) methyltransferase activity(GO:0016433) |
| 0.0 | 0.1 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.1 | GO:0098821 | inhibin binding(GO:0034711) BMP receptor activity(GO:0098821) |
| 0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.1 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.0 | 1.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 2.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.2 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 0.9 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.1 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 60.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 3.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 9.8 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 5.6 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 4.7 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 7.7 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 2.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 1.1 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 27.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 17.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 6.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 0.8 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 3.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 3.8 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.5 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 1.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.0 | 2.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 2.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 2.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.0 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.5 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.0 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 1.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.7 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.6 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.0 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.4 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 1.1 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.4 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 4.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.6 | PID ARF6 PATHWAY | Arf6 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 17.1 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.5 | 51.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.3 | 5.0 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.2 | 1.9 | REACTOME SIGNALING BY FGFR IN DISEASE | Genes involved in Signaling by FGFR in disease |
| 0.2 | 0.7 | REACTOME SIGNALING BY EGFR IN CANCER | Genes involved in Signaling by EGFR in Cancer |
| 0.2 | 6.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 6.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.9 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 3.7 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 2.3 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 1.1 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.1 | 1.1 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 3.0 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 1.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 2.4 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 1.0 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 3.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 2.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 2.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.0 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 2.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 7.8 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.8 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.0 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 2.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.6 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.6 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.4 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 4.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 3.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 2.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.8 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.1 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 1.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.9 | REACTOME SIGNALLING BY NGF | Genes involved in Signalling by NGF |
| 0.0 | 1.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.4 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 0.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 5.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 1.2 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 0.7 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.2 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.8 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.0 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |