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avrg: Illumina Body Map 2 (GSE30611)

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Results for AR_NR3C2

Z-value: 2.10

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Transcription factors associated with AR_NR3C2

Gene Symbol Gene ID Gene Info
AR
ENSG00000169083.18 AR
NR3C2
ENSG00000151623.15 NR3C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARhg38_v1_chrX_+_67543973_675440540.503.3e-03Click!
NR3C2hg38_v1_chr4_-_148442342_148442431-0.125.0e-01Click!

Activity profile of AR_NR3C2 motif

Sorted Z-values of AR_NR3C2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AR_NR3C2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_18266254 12.93 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
SAA1
serum amyloid A1
chr12_+_53050179 11.82 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
TNS2
tensin 2
chr12_+_53050014 9.54 ENST00000314250.11
TNS2
tensin 2
chr1_+_22653228 8.02 ENST00000509305.6
C1QB
complement C1q B chain
chr16_+_56682461 7.94 ENST00000562939.1
ENST00000394485.5
ENST00000567563.1
MT1X
ENSG00000259827.1
metallothionein 1X
novel transcript
chr1_+_22653189 6.60 ENST00000432749.6
C1QB
complement C1q B chain
chr16_+_56632651 6.48 ENST00000379818.4
ENST00000570233.1
MT1M
metallothionein 1M
chr19_+_35139724 6.43 ENST00000588715.5
ENST00000588607.5
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_35140022 5.77 ENST00000588081.5
ENST00000589121.1
FXYD1
FXYD domain containing ion transport regulator 1
chr3_-_58577367 5.30 ENST00000464064.5
ENST00000360997.7
FAM107A
family with sequence similarity 107 member A
chr3_-_58577648 4.91 ENST00000394481.5
FAM107A
family with sequence similarity 107 member A
chr8_+_24440930 4.57 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM7
ADAM metallopeptidase domain 7
chr17_-_19387170 4.49 ENST00000395592.6
ENST00000299610.5
MFAP4
microfibril associated protein 4
chr19_+_35139440 4.47 ENST00000455515.6
FXYD1
FXYD domain containing ion transport regulator 1
chr2_+_237487239 4.42 ENST00000338530.8
ENST00000264605.8
ENST00000409373.5
MLPH
melanophilin
chr18_-_50819982 4.39 ENST00000398439.8
ENST00000431965.6
ENST00000436348.6
MRO
maestro
chr14_-_23154422 4.27 ENST00000422941.6
SLC7A8
solute carrier family 7 member 8
chr19_-_42412347 4.18 ENST00000601189.1
ENST00000599211.1
LIPE
lipase E, hormone sensitive type
chrX_+_8464830 4.16 ENST00000453306.4
ENST00000381032.6
ENST00000444481.3
VCX3B
variable charge X-linked 3B
chr2_+_102337148 4.09 ENST00000311734.6
ENST00000409584.5
IL1RL1
interleukin 1 receptor like 1
chrX_-_6535118 4.06 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
VCX3A
variable charge X-linked 3A
chr16_+_56625775 4.01 ENST00000330439.7
ENST00000568293.1
MT1E
metallothionein 1E
chrY_+_14056226 3.94 ENST00000250823.5
VCY1B
variable charge Y-linked 1B
chr4_+_74445126 3.85 ENST00000395748.8
AREG
amphiregulin
chrY_-_13986473 3.75 ENST00000250825.5
VCY
variable charge Y-linked
chr16_+_56608577 3.58 ENST00000245185.6
ENST00000561491.1
MT2A
metallothionein 2A
chr17_-_19386785 3.56 ENST00000497081.6
MFAP4
microfibril associated protein 4
chrX_+_8465426 3.52 ENST00000381029.4
VCX3B
variable charge X-linked 3B
chr4_+_74445302 3.46 ENST00000502307.1
AREG
amphiregulin
chr14_-_23154369 3.43 ENST00000453702.5
SLC7A8
solute carrier family 7 member 8
chr17_-_8152380 3.35 ENST00000317276.9
PER1
period circadian regulator 1
chrX_+_7843088 2.94 ENST00000341408.5
VCX
variable charge X-linked
chr16_+_56638659 2.93 ENST00000290705.12
MT1A
metallothionein 1A
chr20_-_37158904 2.80 ENST00000417458.5
MROH8
maestro heat like repeat family member 8
chr9_-_35563867 2.68 ENST00000399742.7
ENST00000619051.4
FAM166B
family with sequence similarity 166 member B
chr15_+_42402375 2.65 ENST00000397200.8
ENST00000569827.5
CAPN3
calpain 3
chrX_-_8171267 2.53 ENST00000317103.5
VCX2
variable charge X-linked 2
chr13_+_113122791 2.50 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
F10
coagulation factor X
chr7_-_75611702 2.13 ENST00000616821.4
ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr6_-_111605859 2.09 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3IP2
TRAF3 interacting protein 2
chr18_+_7754959 1.98 ENST00000400053.8
PTPRM
protein tyrosine phosphatase receptor type M
chr4_-_68951763 1.95 ENST00000251566.9
UGT2A3
UDP glucuronosyltransferase family 2 member A3
chr3_-_119677346 1.81 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
COX17
cytochrome c oxidase copper chaperone COX17
chr18_+_49560684 1.78 ENST00000577628.5
LIPG
lipase G, endothelial type
chr3_-_119146014 1.72 ENST00000441144.6
ENST00000425327.6
IGSF11
immunoglobulin superfamily member 11
chrX_-_81121663 1.67 ENST00000430960.5
ENST00000447319.5
HMGN5
high mobility group nucleosome binding domain 5
chr8_-_21812320 1.66 ENST00000517328.5
GFRA2
GDNF family receptor alpha 2
chr10_-_27983103 1.65 ENST00000672841.1
ODAD2
outer dynein arm docking complex subunit 2
chr4_+_87006988 1.56 ENST00000307808.10
AFF1
AF4/FMR2 family member 1
chr19_-_14835162 1.46 ENST00000322301.5
OR7A5
olfactory receptor family 7 subfamily A member 5
chr9_+_128920966 1.43 ENST00000428610.5
ENST00000372592.8
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chrX_-_81121619 1.41 ENST00000373250.7
HMGN5
high mobility group nucleosome binding domain 5
chr19_-_8343255 1.39 ENST00000330915.7
ENST00000593649.5
ENST00000595639.1
KANK3
KN motif and ankyrin repeat domains 3
chr20_-_45547752 1.38 ENST00000409554.1
EPPIN
epididymal peptidase inhibitor
chr3_+_119146159 1.37 ENST00000295622.6
TEX55
testis expressed 55
chrX_+_80014746 1.37 ENST00000373296.8
TBX22
T-box transcription factor 22
chr20_-_45547373 1.35 ENST00000354280.9
EPPIN
epididymal peptidase inhibitor
chr22_-_22559073 1.35 ENST00000420709.5
ENST00000398741.5
PRAME
PRAME nuclear receptor transcriptional regulator
chr3_+_119146184 1.27 ENST00000460150.1
TEX55
testis expressed 55
chr17_+_48841563 1.26 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr8_+_61287950 1.26 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
CLVS1
clavesin 1
chr4_+_87006736 1.25 ENST00000544085.6
AFF1
AF4/FMR2 family member 1
chr22_+_22704265 1.22 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22
chr20_-_45547420 1.21 ENST00000504988.1
EPPIN-WFDC6
EPPIN-WFDC6 readthrough
chr20_-_45547648 1.20 ENST00000651288.1
EPPIN-WFDC6
EPPIN-WFDC6 readthrough
chr14_-_21025490 1.17 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG2
NDRG family member 2
chr16_+_67173971 1.16 ENST00000563258.1
ENST00000568146.1
NOL3
nucleolar protein 3
chr8_+_109540075 1.10 ENST00000614147.1
ENST00000337573.10
EBAG9
estrogen receptor binding site associated antigen 9
chr6_+_127577168 1.09 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr4_+_185426234 1.07 ENST00000511138.5
ENST00000511581.5
ENST00000378850.5
C4orf47
chromosome 4 open reading frame 47
chr1_-_159862648 1.07 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr7_-_94655993 1.07 ENST00000647110.1
ENST00000647048.1
ENST00000643020.1
ENST00000644682.1
ENST00000646119.1
ENST00000646265.1
ENST00000645445.1
ENST00000647334.1
ENST00000645262.1
ENST00000428696.7
ENST00000647096.1
ENST00000642394.1
ENST00000645725.1
ENST00000647351.1
ENST00000646943.1
ENST00000648936.2
ENST00000642707.1
ENST00000645109.1
ENST00000646489.1
ENST00000642933.1
ENST00000643128.1
ENST00000445866.7
ENST00000645101.1
ENST00000644116.1
ENST00000642441.1
ENST00000646879.1
ENST00000647018.1
SGCE
sarcoglycan epsilon
chr15_-_28099293 1.05 ENST00000431101.1
ENST00000445578.5
ENST00000353809.9
ENST00000354638.8
OCA2
OCA2 melanosomal transmembrane protein
chr1_+_103561757 1.03 ENST00000435302.5
AMY2B
amylase alpha 2B
chr17_+_20579724 1.03 ENST00000661883.1
ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15 like 2
chr5_-_173616588 1.02 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
BOD1
biorientation of chromosomes in cell division 1
chr1_-_10796636 0.96 ENST00000377022.8
ENST00000344008.5
CASZ1
castor zinc finger 1
chr16_+_67173935 0.95 ENST00000566871.5
NOL3
nucleolar protein 3
chr12_+_5043873 0.95 ENST00000252321.5
KCNA5
potassium voltage-gated channel subfamily A member 5
chr11_+_90085950 0.95 ENST00000530464.2
UBTFL1
upstream binding transcription factor like 1
chr17_+_39667964 0.92 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr10_-_329480 0.84 ENST00000434695.2
DIP2C
disco interacting protein 2 homolog C
chr12_+_50925007 0.84 ENST00000332160.5
METTL7A
methyltransferase like 7A
chr8_-_144063951 0.83 ENST00000567871.2
OPLAH
5-oxoprolinase, ATP-hydrolysing
chr7_-_97024821 0.83 ENST00000648378.1
ENST00000486603.2
DLX5
distal-less homeobox 5
chr7_+_20615653 0.79 ENST00000404938.7
ABCB5
ATP binding cassette subfamily B member 5
chr4_-_185425941 0.79 ENST00000264689.11
ENST00000505357.1
UFSP2
UFM1 specific peptidase 2
chr11_-_114400417 0.79 ENST00000325636.8
ENST00000623205.2
C11orf71
chromosome 11 open reading frame 71
chr17_+_81097564 0.74 ENST00000576756.5
BAIAP2
BAR/IMD domain containing adaptor protein 2
chr1_-_204149881 0.73 ENST00000444817.1
ETNK2
ethanolamine kinase 2
chr12_-_10098977 0.72 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr1_+_248488589 0.69 ENST00000641363.1
OR2T5
olfactory receptor family 2 subfamily T member 5
chr6_+_18387326 0.69 ENST00000259939.4
RNF144B
ring finger protein 144B
chr19_+_15010720 0.69 ENST00000292574.4
CCDC105
coiled-coil domain containing 105
chr8_-_22156789 0.68 ENST00000306317.7
LGI3
leucine rich repeat LGI family member 3
chr8_-_61689768 0.64 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
ASPH
aspartate beta-hydroxylase
chr18_-_50819764 0.63 ENST00000592966.5
MRO
maestro
chr1_-_24143112 0.63 ENST00000270800.2
IL22RA1
interleukin 22 receptor subunit alpha 1
chr1_+_75796867 0.62 ENST00000263187.4
MSH4
mutS homolog 4
chr8_+_90001448 0.61 ENST00000519410.5
ENST00000522161.5
ENST00000220764.7
ENST00000517761.5
ENST00000520227.1
DECR1
2,4-dienoyl-CoA reductase 1
chr13_+_113759219 0.61 ENST00000375353.5
ENST00000488362.5
TMEM255B
transmembrane protein 255B
chr12_+_10010627 0.58 ENST00000338896.11
ENST00000396502.5
CLEC12B
C-type lectin domain family 12 member B
chr17_-_63773534 0.58 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
CCDC47
coiled-coil domain containing 47
chr14_+_24147474 0.57 ENST00000324103.11
ENST00000559260.5
RNF31
ring finger protein 31
chr16_-_67944113 0.53 ENST00000264005.10
LCAT
lecithin-cholesterol acyltransferase
chr8_-_48921419 0.52 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr16_-_71442033 0.51 ENST00000561754.4
TLE7
TLE family member 7
chr12_-_106086809 0.47 ENST00000548902.1
NUAK1
NUAK family kinase 1
chr19_+_35250563 0.47 ENST00000599658.1
LSR
lipolysis stimulated lipoprotein receptor
chr18_+_58862904 0.47 ENST00000591083.5
ZNF532
zinc finger protein 532
chr14_+_21782993 0.46 ENST00000390429.3
TRAV7
T cell receptor alpha variable 7
chr17_+_81057615 0.41 ENST00000572073.5
ENST00000573677.5
BAIAP2
BAR/IMD domain containing adaptor protein 2
chr4_+_87007175 0.41 ENST00000511722.5
AFF1
AF4/FMR2 family member 1
chr7_-_94656160 0.35 ENST00000644609.1
ENST00000643272.1
ENST00000646137.1
ENST00000646098.1
ENST00000643193.1
ENST00000437425.7
ENST00000644551.1
ENST00000415788.3
SGCE
sarcoglycan epsilon
chr2_-_201769759 0.31 ENST00000680163.1
ENST00000680188.1
ENST00000679550.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chrX_-_117985298 0.30 ENST00000469946.5
KLHL13
kelch like family member 13
chr12_+_125065427 0.29 ENST00000316519.11
AACS
acetoacetyl-CoA synthetase
chr11_-_75669028 0.29 ENST00000304771.8
MAP6
microtubule associated protein 6
chr16_+_8642375 0.28 ENST00000562973.1
METTL22
methyltransferase like 22
chr8_+_7768977 0.28 ENST00000533716.2
FAM90A10P
family with sequence similarity 90 member A10, pseudogene
chr8_-_7582653 0.26 ENST00000648435.1
FAM90A23P
family with sequence similarity 90 member A23, pseudogene
chr22_+_21567705 0.26 ENST00000342192.9
UBE2L3
ubiquitin conjugating enzyme E2 L3
chr11_-_236326 0.26 ENST00000525237.1
ENST00000382743.9
ENST00000532956.5
ENST00000525319.5
ENST00000524564.5
SIRT3
sirtuin 3
chr8_+_7715443 0.25 ENST00000648315.1
FAM90A14P
family with sequence similarity 90 member A14, pseudogene
chr18_+_49561013 0.25 ENST00000583083.1
LIPG
lipase G, endothelial type
chr7_-_94656197 0.25 ENST00000643903.1
ENST00000644122.1
ENST00000447873.6
ENST00000644816.1
ENST00000644375.1
SGCE
sarcoglycan epsilon
chr4_+_37891060 0.23 ENST00000261439.9
ENST00000508802.5
ENST00000402522.1
TBC1D1
TBC1 domain family member 1
chr3_-_134374891 0.23 ENST00000506107.1
AMOTL2
angiomotin like 2
chr8_+_7730739 0.20 ENST00000648174.1
FAM90A16P
family with sequence similarity 90 member A16, pseudogene
chr2_-_75561297 0.20 ENST00000410071.5
ENST00000432649.5
EVA1A
eva-1 homolog A, regulator of programmed cell death
chr3_+_13480215 0.20 ENST00000446613.6
ENST00000402259.5
ENST00000402271.5
ENST00000295757.8
ENST00000404548.5
ENST00000404040.5
HDAC11
histone deacetylase 11
chr12_-_56454653 0.15 ENST00000652304.1
MIP
major intrinsic protein of lens fiber
chr8_-_109603439 0.15 ENST00000533394.5
SYBU
syntabulin
chr2_-_241637045 0.12 ENST00000407315.6
THAP4
THAP domain containing 4
chr12_+_56221977 0.11 ENST00000447747.5
ENST00000399713.6
NABP2
nucleic acid binding protein 2
chr11_+_8911280 0.10 ENST00000530281.5
ENST00000396648.6
ENST00000534147.5
ENST00000529942.1
AKIP1
A-kinase interacting protein 1
chr11_+_114400592 0.10 ENST00000541475.5
RBM7
RNA binding motif protein 7
chr2_+_190180930 0.09 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr17_+_43171187 0.08 ENST00000542611.5
ENST00000590996.6
ENST00000589872.1
NBR1
NBR1 autophagy cargo receptor
chr4_-_8440712 0.08 ENST00000356406.10
ENST00000413009.6
ACOX3
acyl-CoA oxidase 3, pristanoyl
chr18_+_63542365 0.05 ENST00000269491.6
ENST00000382768.2
SERPINB12
serpin family B member 12
chr19_+_55676621 0.04 ENST00000411543.6
EPN1
epsin 1
chr8_-_7559712 0.04 ENST00000650288.1
FAM90A7P
family with sequence similarity 90 member A7, pseudogene
chr19_+_8053000 0.03 ENST00000390669.7
CCL25
C-C motif chemokine ligand 25
chr3_-_24165548 0.02 ENST00000280696.9
THRB
thyroid hormone receptor beta
chr22_+_19951503 0.02 ENST00000406520.7
COMT
catechol-O-methyltransferase
chr8_+_7746034 0.01 ENST00000650426.1
FAM90A17P
family with sequence similarity 90 member A17, pseudogene
chr8_+_7761330 0.01 ENST00000648344.1
FAM90A9P
family with sequence similarity 90 member A9, pseudogene
chr8_+_7738387 0.01 ENST00000647775.1
FAM90A8P
family with sequence similarity 90 member A8, pseudogene
chr8_+_7723091 0.00 ENST00000647769.1
FAM90A18P
family with sequence similarity 90 member A18, pseudogene
chr8_+_7753682 0.00 ENST00000647903.1
FAM90A19P
family with sequence similarity 90 member A19, pseudogene

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.7 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.6 11.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.7 2.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.7 2.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.7 4.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.7 7.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 8.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 1.8 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.6 24.0 GO:0014850 response to muscle activity(GO:0014850)
0.5 4.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 2.0 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 13.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 3.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 2.7 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.3 12.9 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.3 0.9 GO:0042418 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.3 4.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 0.8 GO:0048058 compound eye corneal lens development(GO:0048058)
0.3 2.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.2 0.8 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.6 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.2 7.7 GO:0015695 organic cation transport(GO:0015695)
0.1 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.5 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 1.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 2.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.9 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 3.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 11.4 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 1.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 2.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 2.0 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 2.9 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.9 GO:0001832 blastocyst growth(GO:0001832)
0.0 0.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.6 GO:0006983 ER overload response(GO:0006983)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.8 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 14.1 GO:0007420 brain development(GO:0007420)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.6 GO:0005602 complement component C1 complex(GO:0005602)
0.8 8.0 GO:0071953 elastic fiber(GO:0071953)
0.6 16.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 12.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 2.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0005713 recombination nodule(GO:0005713)
0.1 5.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 2.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 2.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.0 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 5.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 3.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 4.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 3.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.6 GO:0030315 T-tubule(GO:0030315)
0.0 2.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 7.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 19.1 GO:0005925 focal adhesion(GO:0005925)
0.0 20.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 7.0 GO:0016607 nuclear speck(GO:0016607)
0.0 19.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.4 4.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 7.7 GO:0019534 toxin transporter activity(GO:0019534)
0.3 1.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 12.9 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.8 GO:0016531 copper chaperone activity(GO:0016531)
0.2 3.6 GO:0046870 cadmium ion binding(GO:0046870)
0.2 2.1 GO:0089720 caspase binding(GO:0089720)
0.2 1.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 0.6 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.2 16.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 1.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 2.1 GO:0032051 clathrin light chain binding(GO:0032051) AP-2 adaptor complex binding(GO:0035612)
0.1 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 2.6 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 7.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 3.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 13.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 4.4 GO:0017022 myosin binding(GO:0017022)
0.0 11.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 3.4 GO:0070888 E-box binding(GO:0070888)
0.0 4.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064) cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 18.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.4 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 7.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 15.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 8.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 12.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 7.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 4.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 3.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels