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avrg: Illumina Body Map 2 (GSE30611)

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Results for BATF3

Z-value: 1.00

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Transcription factors associated with BATF3

Gene Symbol Gene ID Gene Info
BATF3
ENSG00000123685.9 BATF3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATF3hg38_v1_chr1_-_212699817_212699846-0.019.6e-01Click!

Activity profile of BATF3 motif

Sorted Z-values of BATF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_172771187 5.23 ENST00000239223.4
DUSP1
dual specificity phosphatase 1
chr22_+_38201932 2.05 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAFF
MAF bZIP transcription factor F
chr14_-_49586325 1.99 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
RPS29
ribosomal protein S29
chr6_+_139135063 1.80 ENST00000367658.3
HECA
hdc homolog, cell cycle regulator
chr2_+_69915041 1.76 ENST00000540449.5
MXD1
MAX dimerization protein 1
chr2_+_69915100 1.69 ENST00000264444.7
MXD1
MAX dimerization protein 1
chr11_+_12674555 1.49 ENST00000527376.3
TEAD1
TEA domain transcription factor 1
chr6_-_90296908 1.47 ENST00000537989.5
BACH2
BTB domain and CNC homolog 2
chr6_-_90296824 1.42 ENST00000257749.9
BACH2
BTB domain and CNC homolog 2
chrX_+_43654888 1.41 ENST00000542639.5
MAOA
monoamine oxidase A
chr6_-_90296742 1.34 ENST00000343122.7
ENST00000406998.6
ENST00000453877.5
BACH2
BTB domain and CNC homolog 2
chr17_+_36103819 1.33 ENST00000615863.2
ENST00000621626.1
CCL4
C-C motif chemokine ligand 4
chr6_+_89081787 1.30 ENST00000354922.3
PNRC1
proline rich nuclear receptor coactivator 1
chr14_+_67619911 1.21 ENST00000261783.4
ARG2
arginase 2
chr3_-_134373719 1.11 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr16_+_3018390 1.08 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr2_-_74529670 1.06 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr10_+_122163426 1.05 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr3_+_38165484 1.03 ENST00000446845.5
ENST00000311806.8
OXSR1
oxidative stress responsive kinase 1
chr2_+_219206768 1.03 ENST00000289528.10
ENST00000409206.5
ENST00000444522.6
ENST00000621130.4
ENST00000409594.5
ENST00000422255.5
ENST00000409412.5
ENST00000409097.5
ENST00000409336.5
ENST00000409217.5
ZFAND2B
zinc finger AN1-type containing 2B
chrX_-_135973684 1.00 ENST00000681201.1
MMGT1
membrane magnesium transporter 1
chr14_+_21894433 0.99 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chrX_-_135973975 0.99 ENST00000305963.3
ENST00000680510.1
ENST00000679621.1
MMGT1
membrane magnesium transporter 1
chr14_+_21846534 0.98 ENST00000390434.3
TRAV8-2
T cell receptor alpha variable 8-2
chr1_+_1001002 0.97 ENST00000624697.4
ENST00000624652.1
ISG15
ISG15 ubiquitin like modifier
chr5_-_176537361 0.96 ENST00000274811.9
RNF44
ring finger protein 44
chr10_+_122163590 0.95 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chrX_+_48539665 0.93 ENST00000376771.9
ENST00000418627.1
TBC1D25
TBC1 domain family member 25
chr3_-_119463659 0.91 ENST00000468676.5
TMEM39A
transmembrane protein 39A
chr1_+_156061142 0.91 ENST00000361084.10
RAB25
RAB25, member RAS oncogene family
chr2_+_10043524 0.90 ENST00000305883.6
KLF11
Kruppel like factor 11
chr14_-_77028663 0.85 ENST00000238647.5
IRF2BPL
interferon regulatory factor 2 binding protein like
chr2_+_219206875 0.84 ENST00000409319.5
ZFAND2B
zinc finger AN1-type containing 2B
chr2_+_10044175 0.83 ENST00000440320.5
ENST00000535335.1
KLF11
Kruppel like factor 11
chr6_+_32972187 0.79 ENST00000607833.5
BRD2
bromodomain containing 2
chr2_-_65130090 0.79 ENST00000398529.7
ENST00000409751.1
ENST00000409892.5
ENST00000409784.8
RAB1A
RAB1A, member RAS oncogene family
chr3_-_52278321 0.73 ENST00000469000.5
WDR82
WD repeat domain 82
chr10_+_122163672 0.71 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr17_+_8247601 0.67 ENST00000585183.5
PFAS
phosphoribosylformylglycinamidine synthase
chr1_+_153778178 0.66 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr12_-_122896066 0.64 ENST00000267202.7
ENST00000535765.5
VPS37B
VPS37B subunit of ESCRT-I
chr19_+_47113425 0.64 ENST00000594526.5
SAE1
SUMO1 activating enzyme subunit 1
chr2_-_219399981 0.63 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
DNPEP
aspartyl aminopeptidase
chr3_-_119463606 0.61 ENST00000319172.10
ENST00000491685.5
ENST00000461654.1
TMEM39A
transmembrane protein 39A
chr12_+_10212483 0.58 ENST00000545859.5
GABARAPL1
GABA type A receptor associated protein like 1
chr19_-_47113756 0.56 ENST00000253048.10
ZC3H4
zinc finger CCCH-type containing 4
chr10_+_35195843 0.52 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr2_-_201780878 0.50 ENST00000681152.1
ENST00000681312.1
ENST00000409632.7
ENST00000264276.11
ENST00000410052.1
ENST00000681303.1
ENST00000680287.1
ENST00000467448.5
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr3_-_101686690 0.49 ENST00000469605.1
ENST00000495401.5
ENST00000394077.8
RPL24
ribosomal protein L24
chr3_+_184338826 0.48 ENST00000453072.5
FAM131A
family with sequence similarity 131 member A
chr2_-_65432591 0.45 ENST00000356388.9
SPRED2
sprouty related EVH1 domain containing 2
chr7_-_94004372 0.43 ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr12_+_10212836 0.42 ENST00000421801.6
ENST00000544284.5
GABARAPL1
GABA type A receptor associated protein like 1
chr2_-_201781112 0.38 ENST00000681808.1
ENST00000681619.1
ENST00000680759.1
ENST00000680814.1
ENST00000680000.1
ENST00000679949.1
ENST00000679728.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr11_+_102347205 0.38 ENST00000532832.5
ENST00000530675.5
ENST00000227758.7
ENST00000533742.5
ENST00000532672.5
ENST00000531259.5
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr11_-_85665077 0.37 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr10_+_131900999 0.36 ENST00000455566.6
PPP2R2D
protein phosphatase 2 regulatory subunit Bdelta
chr7_-_94004345 0.35 ENST00000222547.8
ENST00000433727.5
BET1
Bet1 golgi vesicular membrane trafficking protein
chr2_-_65432628 0.34 ENST00000440972.1
SPRED2
sprouty related EVH1 domain containing 2
chr17_-_7931910 0.33 ENST00000303731.9
ENST00000571947.5
ENST00000540486.5
ENST00000572656.2
TRAPPC1
trafficking protein particle complex 1
chr12_+_10212867 0.33 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABARAPL1
GABA type A receptor associated protein like 1
chr11_+_12674397 0.32 ENST00000527636.7
TEAD1
TEA domain transcription factor 1
chr8_-_66178455 0.30 ENST00000276571.5
CRH
corticotropin releasing hormone
chr22_+_37563640 0.30 ENST00000415670.1
CDC42EP1
CDC42 effector protein 1
chr14_-_24263532 0.30 ENST00000558074.1
ENST00000560226.1
TGM1
transglutaminase 1
chr2_+_74529923 0.30 ENST00000258080.8
ENST00000352222.7
HTRA2
HtrA serine peptidase 2
chr11_+_102347312 0.29 ENST00000621637.1
ENST00000613397.4
BIRC2
baculoviral IAP repeat containing 2
chr3_-_52278620 0.25 ENST00000296490.8
WDR82
WD repeat domain 82
chr19_+_8390316 0.25 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr15_+_42548810 0.24 ENST00000568876.5
ENST00000568846.6
ENST00000562398.5
ENST00000260372.8
HAUS2
HAUS augmin like complex subunit 2
chr2_+_74530018 0.20 ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr3_+_128879590 0.20 ENST00000681367.1
ENST00000680636.1
ENST00000308982.12
ENST00000681552.1
ENST00000514336.1
ACAD9
acyl-CoA dehydrogenase family member 9
chr15_-_42548763 0.19 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
LRRC57
leucine rich repeat containing 57
chr6_-_106325735 0.19 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
ATG5
autophagy related 5
chr17_+_31094969 0.15 ENST00000431387.8
ENST00000358273.9
NF1
neurofibromin 1
chr16_-_3018170 0.15 ENST00000572154.1
ENST00000328796.5
CLDN6
claudin 6
chr6_-_106325416 0.14 ENST00000343245.7
ATG5
autophagy related 5
chr6_-_106325616 0.13 ENST00000360666.6
ATG5
autophagy related 5
chr16_-_68023201 0.13 ENST00000332395.7
DDX28
DEAD-box helicase 28
chr18_-_47251660 0.12 ENST00000425639.3
SKOR2
SKI family transcriptional corepressor 2
chr4_-_39366342 0.12 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
RFC1
replication factor C subunit 1
chr8_+_37736612 0.12 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ERLIN2
ER lipid raft associated 2
chr6_+_31971831 0.09 ENST00000375331.7
ENST00000375333.3
STK19
serine/threonine kinase 19
chr14_-_24263162 0.07 ENST00000206765.11
ENST00000544573.5
TGM1
transglutaminase 1
chr19_-_51002527 0.06 ENST00000595238.1
ENST00000600767.5
KLK8
kallikrein related peptidase 8
chr1_+_109984756 0.05 ENST00000393614.8
ENST00000369799.10
AHCYL1
adenosylhomocysteinase like 1
chr10_+_97737115 0.04 ENST00000337540.11
ENST00000370613.7
ENST00000370610.7
ENST00000357540.8
ENST00000393677.8
ENST00000423811.3
ENST00000684270.1
ENST00000359980.5
ZFYVE27
zinc finger FYVE-type containing 27
chr16_+_68023249 0.01 ENST00000358896.10
ENST00000568099.6
DUS2
dihydrouridine synthase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 1.0 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 1.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.9 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 0.9 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 0.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 1.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 1.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:0070093 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 1.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 1.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.2 GO:0000050 urea cycle(GO:0000050)
0.1 0.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.1 GO:0007567 parturition(GO:0007567)
0.1 0.9 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 1.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.9 GO:0035329 hippo signaling(GO:0035329)
0.0 1.2 GO:0031268 pseudopodium organization(GO:0031268)
0.0 1.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 1.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0061534 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 2.7 GO:0021987 cerebral cortex development(GO:0021987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 1.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 1.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.6 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.2 4.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.0 GO:0031386 protein tag(GO:0031386)
0.1 1.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 3.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway