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avrg: Illumina Body Map 2 (GSE30611)

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Results for CEBPB

Z-value: 2.62

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Transcription factors associated with CEBPB

Gene Symbol Gene ID Gene Info
CEBPB
ENSG00000172216.6 CEBPB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPBhg38_v1_chr20_+_50190821_501908390.309.1e-02Click!

Activity profile of CEBPB motif

Sorted Z-values of CEBPB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_154612635 10.07 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
FGG
fibrinogen gamma chain
chr16_+_72054477 9.34 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr20_+_57561103 8.72 ENST00000319441.6
PCK1
phosphoenolpyruvate carboxykinase 1
chr20_+_38346474 8.46 ENST00000217407.3
LBP
lipopolysaccharide binding protein
chr17_-_66220630 7.91 ENST00000585162.1
APOH
apolipoprotein H
chr3_+_186717348 6.96 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
KNG1
kininogen 1
chr19_-_4540028 6.42 ENST00000306390.7
LRG1
leucine rich alpha-2-glycoprotein 1
chr9_-_34691204 6.32 ENST00000378800.3
ENST00000311925.7
CCL19
C-C motif chemokine ligand 19
chr22_+_35381086 6.12 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
HMOX1
heme oxygenase 1
chr5_+_151020438 5.73 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr12_+_57454674 5.50 ENST00000547970.1
INHBE
inhibin subunit beta E
chr20_+_380747 5.43 ENST00000217233.9
TRIB3
tribbles pseudokinase 3
chr1_-_203229660 5.35 ENST00000255427.7
ENST00000367229.6
CHIT1
chitinase 1
chr3_-_49685090 5.31 ENST00000448220.5
MST1
macrophage stimulating 1
chr6_+_31927703 5.22 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
C2
ENSG00000244255.5
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr6_+_31927683 5.14 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr2_+_240868817 5.02 ENST00000307503.4
AGXT
alanine--glyoxylate and serine--pyruvate aminotransferase
chr6_+_31927486 4.98 ENST00000442278.6
C2
complement C2
chr5_-_142325001 4.93 ENST00000344120.4
ENST00000434127.3
SPRY4
sprouty RTK signaling antagonist 4
chr20_+_381246 4.82 ENST00000449710.5
ENST00000422053.3
TRIB3
tribbles pseudokinase 3
chr2_+_210556590 4.70 ENST00000233072.10
ENST00000619804.1
CPS1
carbamoyl-phosphate synthase 1
chr11_+_114296347 4.61 ENST00000299964.4
NNMT
nicotinamide N-methyltransferase
chr6_+_31927510 3.99 ENST00000447952.6
C2
complement C2
chr12_-_7128873 3.73 ENST00000542370.1
ENST00000266560.8
RBP5
retinol binding protein 5
chr12_+_57455266 3.69 ENST00000266646.3
INHBE
inhibin subunit beta E
chr22_-_30246739 3.67 ENST00000403987.3
ENST00000249075.4
LIF
LIF interleukin 6 family cytokine
chr12_+_57229694 3.54 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
SHMT2
serine hydroxymethyltransferase 2
chr12_+_57230086 3.52 ENST00000414700.7
ENST00000557703.5
SHMT2
serine hydroxymethyltransferase 2
chr21_-_6467509 3.30 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
CBSL
cystathionine beta-synthase like
chr12_-_55842950 3.17 ENST00000548629.5
MMP19
matrix metallopeptidase 19
chr12_-_95996302 3.03 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr17_+_1762052 3.00 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
SERPINF1
serpin family F member 1
chr22_-_30505650 2.95 ENST00000381982.3
ENST00000255858.12
SEC14L4
SEC14 like lipid binding 4
chr1_+_28259473 2.87 ENST00000253063.4
SESN2
sestrin 2
chr12_+_57230336 2.81 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
SHMT2
serine hydroxymethyltransferase 2
chr21_-_43075831 2.80 ENST00000398158.5
ENST00000398165.8
CBS
cystathionine beta-synthase
chr5_+_52787899 2.76 ENST00000274311.3
ENST00000282588.7
PELO
ITGA1
pelota mRNA surveillance and ribosome rescue factor
integrin subunit alpha 1
chr19_-_32869741 2.75 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
SLC7A9
solute carrier family 7 member 9
chr3_+_101849505 2.72 ENST00000326151.9
ENST00000326172.9
NFKBIZ
NFKB inhibitor zeta
chr12_+_57230301 2.71 ENST00000553474.5
SHMT2
serine hydroxymethyltransferase 2
chr11_+_7485492 2.64 ENST00000534244.1
ENST00000329293.4
OLFML1
olfactomedin like 1
chr16_-_28539004 2.62 ENST00000395641.2
NUPR1
nuclear protein 1, transcriptional regulator
chr1_+_212608628 2.62 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
ATF3
activating transcription factor 3
chr19_-_11236497 2.55 ENST00000587656.5
DOCK6
dedicator of cytokinesis 6
chr6_-_134177898 2.53 ENST00000528577.5
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_57230124 2.43 ENST00000553529.5
ENST00000554310.5
SHMT2
serine hydroxymethyltransferase 2
chr17_+_41689862 2.40 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr2_-_159798234 2.38 ENST00000429078.6
ENST00000553424.5
CD302
CD302 molecule
chr17_+_1762012 2.37 ENST00000571360.5
SERPINF1
serpin family F member 1
chr15_+_88639009 2.30 ENST00000306072.10
ISG20
interferon stimulated exonuclease gene 20
chr1_-_27626229 2.29 ENST00000399173.5
FGR
FGR proto-oncogene, Src family tyrosine kinase
chr19_-_35513641 2.28 ENST00000339686.8
ENST00000447113.6
DMKN
dermokine
chr5_+_38846002 2.19 ENST00000274276.8
OSMR
oncostatin M receptor
chr6_+_150865815 2.18 ENST00000367308.8
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr15_+_88638947 2.17 ENST00000559876.2
ISG20
interferon stimulated exonuclease gene 20
chr9_-_92536031 2.09 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr15_+_96325935 2.09 ENST00000421109.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr3_+_157436842 2.08 ENST00000295927.4
PTX3
pentraxin 3
chr5_+_38845824 2.07 ENST00000502536.5
OSMR
oncostatin M receptor
chr14_-_91946989 2.04 ENST00000556154.5
FBLN5
fibulin 5
chr2_-_159798043 2.00 ENST00000664982.1
ENST00000259053.6
ENSG00000287091.1
CD302
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr1_-_27626496 1.98 ENST00000374003.7
FGR
FGR proto-oncogene, Src family tyrosine kinase
chr1_-_196608359 1.97 ENST00000609185.5
ENST00000451324.6
ENST00000367433.9
ENST00000294725.14
KCNT2
potassium sodium-activated channel subfamily T member 2
chr3_+_12351470 1.93 ENST00000287820.10
PPARG
peroxisome proliferator activated receptor gamma
chr12_-_55842927 1.92 ENST00000322569.9
ENST00000409200.7
MMP19
matrix metallopeptidase 19
chr7_+_114922346 1.91 ENST00000393486.5
MDFIC
MyoD family inhibitor domain containing
chr2_+_6978624 1.87 ENST00000433456.1
RNF144A
ring finger protein 144A
chr16_-_28538951 1.83 ENST00000324873.8
NUPR1
nuclear protein 1, transcriptional regulator
chr11_-_102724945 1.83 ENST00000236826.8
MMP8
matrix metallopeptidase 8
chr1_-_36482904 1.82 ENST00000373106.6
CSF3R
colony stimulating factor 3 receptor
chrX_+_13569593 1.82 ENST00000361306.6
ENST00000380602.3
EGFL6
EGF like domain multiple 6
chr3_-_3110347 1.76 ENST00000383846.5
ENST00000427088.1
ENST00000446632.7
ENST00000418488.6
ENST00000438560.5
IL5RA
interleukin 5 receptor subunit alpha
chr6_-_32844643 1.74 ENST00000374881.3
PSMB8
proteasome 20S subunit beta 8
chr11_+_7485353 1.74 ENST00000530135.5
OLFML1
olfactomedin like 1
chr11_+_7485606 1.73 ENST00000528758.1
OLFML1
olfactomedin like 1
chr1_+_53062052 1.73 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
PODN
podocan
chr19_-_54313074 1.72 ENST00000486742.2
ENST00000432233.8
LILRA5
leukocyte immunoglobulin like receptor A5
chr2_+_113127588 1.70 ENST00000409930.4
IL1RN
interleukin 1 receptor antagonist
chrX_-_107000185 1.70 ENST00000355610.9
MORC4
MORC family CW-type zinc finger 4
chr6_+_30720335 1.66 ENST00000327892.13
TUBB
tubulin beta class I
chr5_+_150640652 1.65 ENST00000307662.5
SYNPO
synaptopodin
chr3_+_12351493 1.64 ENST00000683699.1
PPARG
peroxisome proliferator activated receptor gamma
chr1_+_53014926 1.64 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
SCP2
sterol carrier protein 2
chr2_-_216694794 1.61 ENST00000449583.1
IGFBP5
insulin like growth factor binding protein 5
chr1_+_111473792 1.61 ENST00000343534.9
C1orf162
chromosome 1 open reading frame 162
chr1_-_27626106 1.60 ENST00000457296.5
FGR
FGR proto-oncogene, Src family tyrosine kinase
chr11_-_102798148 1.60 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr4_+_76639517 1.57 ENST00000646790.1
SHROOM3
shroom family member 3
chr6_+_150866333 1.55 ENST00000618312.4
ENST00000423867.2
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chrX_-_110440218 1.53 ENST00000372057.1
ENST00000372054.3
AMMECR1
GNG5P2
AMMECR nuclear protein 1
G protein subunit gamma 5 pseudogene 2
chr12_+_57230274 1.51 ENST00000557427.5
SHMT2
serine hydroxymethyltransferase 2
chr1_-_204411804 1.51 ENST00000367188.5
PPP1R15B
protein phosphatase 1 regulatory subunit 15B
chr19_-_46784905 1.50 ENST00000594991.5
SLC1A5
solute carrier family 1 member 5
chr5_-_102296260 1.49 ENST00000310954.7
SLCO4C1
solute carrier organic anion transporter family member 4C1
chr16_+_56936654 1.49 ENST00000563911.5
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
chr9_+_128920966 1.49 ENST00000428610.5
ENST00000372592.8
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr19_+_11239602 1.49 ENST00000252453.12
ANGPTL8
angiopoietin like 8
chr1_-_206970457 1.46 ENST00000324852.9
ENST00000450945.3
ENST00000400962.8
FCAMR
Fc fragment of IgA and IgM receptor
chr9_-_92536067 1.43 ENST00000444490.6
ECM2
extracellular matrix protein 2
chr3_+_9423108 1.41 ENST00000468208.2
SETD5
SET domain containing 5
chrX_-_107000062 1.39 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr7_-_116030735 1.38 ENST00000393485.5
TFEC
transcription factor EC
chr17_-_81937320 1.38 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
PYCR1
pyrroline-5-carboxylate reductase 1
chr2_-_43226594 1.37 ENST00000282388.4
ZFP36L2
ZFP36 ring finger protein like 2
chr1_+_153259684 1.37 ENST00000368742.4
LORICRIN
loricrin cornified envelope precursor protein
chr8_+_22392821 1.37 ENST00000520832.1
SLC39A14
solute carrier family 39 member 14
chr12_-_6341848 1.33 ENST00000366159.8
ENST00000539372.5
TNFRSF1A
TNF receptor superfamily member 1A
chr11_-_65133320 1.32 ENST00000531018.5
SYVN1
synoviolin 1
chr10_+_26438404 1.29 ENST00000356785.4
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
chr14_-_24576240 1.28 ENST00000216336.3
CTSG
cathepsin G
chr3_+_42856021 1.25 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr12_-_6342020 1.22 ENST00000540022.5
ENST00000536194.1
TNFRSF1A
TNF receptor superfamily member 1A
chr12_-_6342066 1.22 ENST00000162749.7
ENST00000440083.6
TNFRSF1A
TNF receptor superfamily member 1A
chr1_+_111473972 1.21 ENST00000369718.4
C1orf162
chromosome 1 open reading frame 162
chr10_+_26438317 1.20 ENST00000376236.9
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
chr1_-_44031446 1.19 ENST00000372310.8
ENST00000466926.1
SLC6A9
solute carrier family 6 member 9
chr1_-_32817311 1.18 ENST00000373477.9
ENST00000675785.1
YARS1
tyrosyl-tRNA synthetase 1
chr16_-_4273014 1.17 ENST00000204517.11
TFAP4
transcription factor AP-4
chr16_+_56932134 1.16 ENST00000439977.7
ENST00000300302.9
ENST00000344114.8
ENST00000379792.6
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
chr3_+_128051610 1.16 ENST00000464451.5
SEC61A1
SEC61 translocon subunit alpha 1
chr15_-_82571741 1.12 ENST00000562833.2
ENST00000611163.4
ENSG00000260836.2
CPEB1
novel protein
cytoplasmic polyadenylation element binding protein 1
chr20_-_2840623 1.11 ENST00000360652.7
ENST00000448755.5
PCED1A
PC-esterase domain containing 1A
chr9_+_2621766 1.09 ENST00000382100.8
VLDLR
very low density lipoprotein receptor
chr12_+_55997180 1.06 ENST00000356124.8
ENST00000266971.8
ENST00000394115.6
ENST00000547586.5
ENST00000552258.5
ENST00000548274.5
ENST00000546833.5
SUOX
sulfite oxidase
chr14_-_91947383 1.05 ENST00000267620.14
FBLN5
fibulin 5
chr7_+_114922561 1.04 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr16_-_57775103 1.03 ENST00000540079.6
ENST00000569222.5
KIFC3
kinesin family member C3
chr11_-_102724781 1.02 ENST00000438475.2
MMP8
matrix metallopeptidase 8
chr19_-_46784733 1.02 ENST00000593713.1
ENST00000598022.1
ENST00000434726.6
SLC1A5
solute carrier family 1 member 5
chr12_+_9971402 1.00 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
CLEC12A
C-type lectin domain family 12 member A
chrX_+_100584928 0.99 ENST00000373031.5
TNMD
tenomodulin
chr1_+_98661666 0.98 ENST00000529992.5
SNX7
sorting nexin 7
chr5_+_73813518 0.98 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr1_-_237945275 0.98 ENST00000604646.1
MTRNR2L11
MT-RNR2 like 11
chr3_-_3109980 0.96 ENST00000256452.7
ENST00000311981.12
ENST00000430514.6
ENST00000456302.5
IL5RA
interleukin 5 receptor subunit alpha
chrX_-_54998530 0.96 ENST00000545676.5
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_48171451 0.96 ENST00000435803.6
ABCA13
ATP binding cassette subfamily A member 13
chr12_-_52680398 0.95 ENST00000252244.3
KRT1
keratin 1
chr7_-_116030750 0.94 ENST00000265440.12
ENST00000320239.11
TFEC
transcription factor EC
chr18_+_31447732 0.92 ENST00000257189.5
DSG3
desmoglein 3
chr1_-_149936324 0.92 ENST00000369140.7
MTMR11
myotubularin related protein 11
chr5_+_179678613 0.91 ENST00000681674.1
ENST00000681712.1
ENST00000681903.1
CANX
calnexin
chr8_-_22109381 0.90 ENST00000613958.1
ENST00000611621.2
NUDT18
nudix hydrolase 18
chr6_+_31971831 0.88 ENST00000375331.7
ENST00000375333.3
STK19
serine/threonine kinase 19
chrX_+_116436599 0.88 ENST00000598581.3
SLC6A14
solute carrier family 6 member 14
chr12_+_111405861 0.85 ENST00000341259.7
SH2B3
SH2B adaptor protein 3
chr14_+_75428011 0.85 ENST00000651602.1
ENST00000559060.5
JDP2
Jun dimerization protein 2
chr12_-_95995920 0.84 ENST00000552509.5
HAL
histidine ammonia-lyase
chrX_+_24054931 0.83 ENST00000253039.9
ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2 subunit gamma
chr17_-_40822604 0.83 ENST00000269576.6
ENST00000635956.2
KRT10
keratin 10
chr12_+_10213624 0.83 ENST00000545290.1
GABARAPL1
GABA type A receptor associated protein like 1
chr17_-_81937277 0.82 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
PYCR1
pyrroline-5-carboxylate reductase 1
chr8_+_38974212 0.81 ENST00000302495.5
HTRA4
HtrA serine peptidase 4
chr12_-_57520480 0.80 ENST00000642841.1
ENST00000547303.5
ENST00000552740.5
ENST00000547526.1
ENST00000346473.8
ENST00000551116.5
ENSG00000285133.1
DDIT3
novel protein
DNA damage inducible transcript 3
chr1_+_99646025 0.79 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr20_-_2841109 0.78 ENST00000356872.7
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr17_-_10469558 0.76 ENST00000255381.2
MYH4
myosin heavy chain 4
chr18_+_74501090 0.76 ENST00000582666.5
CNDP2
carnosine dipeptidase 2
chr1_-_37947010 0.76 ENST00000458109.6
ENST00000373024.8
ENST00000373023.6
INPP5B
inositol polyphosphate-5-phosphatase B
chr1_+_162631984 0.75 ENST00000415555.5
DDR2
discoidin domain receptor tyrosine kinase 2
chr20_+_41340780 0.72 ENST00000373257.8
LPIN3
lipin 3
chr12_+_57520959 0.71 ENST00000551351.5
MBD6
methyl-CpG binding domain protein 6
chr5_-_151093566 0.70 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr15_-_79971164 0.70 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr11_+_62881686 0.69 ENST00000536981.6
ENST00000539891.6
SLC3A2
solute carrier family 3 member 2
chr4_-_156970903 0.69 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr6_+_32844789 0.68 ENST00000414474.5
PSMB9
proteasome 20S subunit beta 9
chr3_+_141386393 0.67 ENST00000503809.5
ZBTB38
zinc finger and BTB domain containing 38
chr20_+_41340878 0.67 ENST00000632009.1
LPIN3
lipin 3
chr11_+_119084873 0.66 ENST00000652429.1
ENST00000442944.7
ENST00000537841.5
ENST00000542729.5
ENST00000546302.6
ENST00000536813.6
ENST00000544387.5
ENST00000543090.5
HMBS
hydroxymethylbilane synthase
chr14_+_19876232 0.65 ENST00000298642.2
OR4K2
olfactory receptor family 4 subfamily K member 2
chr17_+_30921935 0.62 ENST00000581285.5
ENST00000330889.8
ADAP2
ArfGAP with dual PH domains 2
chr19_+_48756067 0.61 ENST00000222157.5
FGF21
fibroblast growth factor 21
chr9_+_2621556 0.61 ENST00000680746.1
VLDLR
very low density lipoprotein receptor
chr10_+_113125536 0.59 ENST00000349937.7
TCF7L2
transcription factor 7 like 2
chr19_+_35745613 0.57 ENST00000222266.2
ENST00000587708.7
PSENEN
presenilin enhancer, gamma-secretase subunit
chr15_+_62066975 0.56 ENST00000355522.5
C2CD4A
C2 calcium dependent domain containing 4A
chr6_+_127577168 0.55 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr17_-_81937221 0.55 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
PYCR1
pyrroline-5-carboxylate reductase 1
chr15_+_40952962 0.55 ENST00000444189.7
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr14_+_75427688 0.55 ENST00000419727.6
JDP2
Jun dimerization protein 2
chr4_-_69860138 0.55 ENST00000226444.4
SULT1E1
sulfotransferase family 1E member 1
chr17_+_30921899 0.52 ENST00000581548.5
ENST00000580525.5
ADAP2
ArfGAP with dual PH domains 2
chr1_+_43650466 0.51 ENST00000463151.5
KDM4A
lysine demethylase 4A
chr12_+_57520698 0.50 ENST00000548887.5
MBD6
methyl-CpG binding domain protein 6
chr4_+_146214515 0.50 ENST00000636502.1
REELD1
reeler domain containing 1
chr7_+_80133830 0.50 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
GNAI1
G protein subunit alpha i1
chr10_-_21517825 0.49 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr19_+_35745590 0.49 ENST00000591949.1
PSENEN
presenilin enhancer, gamma-secretase subunit
chr19_-_54081365 0.47 ENST00000432826.2
TARM1
T cell-interacting, activating receptor on myeloid cells 1
chr1_-_109613070 0.47 ENST00000351050.8
GNAT2
G protein subunit alpha transducin 2
chr18_+_63752935 0.47 ENST00000425392.5
ENST00000336429.6
SERPINB7
serpin family B member 7
chr6_+_125781108 0.45 ENST00000368357.7
NCOA7
nuclear receptor coactivator 7
chr5_+_33440947 0.44 ENST00000455217.6
ENST00000265112.8
TARS1
threonyl-tRNA synthetase 1
chr1_-_44031352 0.40 ENST00000372306.7
ENST00000475075.6
SLC6A9
solute carrier family 6 member 9
chr9_-_13175824 0.39 ENST00000545857.5
MPDZ
multiple PDZ domain crumbs cell polarity complex component
chr1_+_25430854 0.37 ENST00000399766.7
MACO1
macoilin 1
chr20_-_34112205 0.36 ENST00000374980.3
EIF2S2
eukaryotic translation initiation factor 2 subunit beta
chr1_-_145962581 0.36 ENST00000619813.1
ANKRD34A
ankyrin repeat domain 34A
chr2_-_213152427 0.35 ENST00000452786.2
IKZF2
IKAROS family zinc finger 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.9 8.7 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
2.8 8.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
2.1 6.3 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
1.8 16.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.6 4.7 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.3 5.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
1.2 6.1 GO:0006788 heme oxidation(GO:0006788) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
1.1 4.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.0 2.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.9 14.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.9 3.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 6.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.8 5.7 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.8 5.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.7 3.7 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.7 2.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.7 7.9 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.7 2.6 GO:1903984 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 2.5 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.6 5.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.6 3.9 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.5 2.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.5 1.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.5 4.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 1.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 2.1 GO:0009956 radial pattern formation(GO:0009956)
0.5 5.1 GO:0001554 luteolysis(GO:0001554)
0.5 2.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.4 3.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 17.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 2.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 2.4 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 1.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.3 8.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 2.8 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.3 0.9 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 5.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 3.8 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 1.7 GO:0034436 glycoprotein transport(GO:0034436)
0.2 2.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 5.9 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 4.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 4.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 0.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 0.7 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.5 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2 1.2 GO:0039019 pronephric nephron development(GO:0039019)
0.2 1.3 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 1.0 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 1.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 6.4 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.8 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 2.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.3 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.1 8.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.0 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.1 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 1.4 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 1.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.7 GO:0060356 leucine import(GO:0060356)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 1.5 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.1 1.8 GO:0097186 amelogenesis(GO:0097186)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 3.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 1.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 1.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 4.4 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 4.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 1.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 5.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0018963 phthalate metabolic process(GO:0018963)
0.0 1.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.4 4.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
1.3 16.5 GO:0070552 BRISC complex(GO:0070552)
1.1 3.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.8 9.9 GO:0005577 fibrinogen complex(GO:0005577)
0.6 2.8 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.4 7.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 3.1 GO:0071953 elastic fiber(GO:0071953)
0.3 2.7 GO:1990037 Lewy body core(GO:1990037)
0.3 2.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 2.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 5.1 GO:0043203 axon hillock(GO:0043203)
0.2 16.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 6.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 5.9 GO:0016235 aggresome(GO:0016235)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 6.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 4.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 1.2 GO:0010369 chromocenter(GO:0010369)
0.0 1.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.0 GO:0005915 zonula adherens(GO:0005915)
0.0 2.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 6.1 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 3.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 3.2 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 2.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 45.4 GO:0005615 extracellular space(GO:0005615)
0.0 3.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 7.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.8 16.5 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.5 4.5 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 9.3 GO:0030492 hemoglobin binding(GO:0030492)
1.3 7.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.2 6.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.2 4.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.1 6.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.9 8.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.9 6.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.8 5.0 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.7 3.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.7 4.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.7 3.5 GO:0070052 collagen V binding(GO:0070052)
0.7 5.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 1.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.6 3.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 1.6 GO:0070538 oleic acid binding(GO:0070538)
0.5 2.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.5 10.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 3.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 1.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.4 1.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 2.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 2.9 GO:0070728 leucine binding(GO:0070728)
0.3 5.3 GO:0004568 chitinase activity(GO:0004568)
0.3 2.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 0.9 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.3 3.6 GO:0050692 DBD domain binding(GO:0050692)
0.3 5.7 GO:0008430 selenium binding(GO:0008430)
0.2 3.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 14.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 3.7 GO:0019841 retinol binding(GO:0019841)
0.1 3.7 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 1.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 1.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 31.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 2.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 7.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 1.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 2.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 4.6 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 4.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 1.5 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 5.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 2.7 PID IL5 PATHWAY IL5-mediated signaling events
0.2 11.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 9.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 8.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 5.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.6 ST ADRENERGIC Adrenergic Pathway
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 20.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 3.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 14.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 2.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.6 14.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 10.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 10.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 8.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 7.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 7.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 6.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 3.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 15.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 4.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 5.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 4.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 6.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events