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avrg: Illumina Body Map 2 (GSE30611)

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Results for CEBPG

Z-value: 2.12

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.9 CEBPG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg38_v1_chr19_+_33373694_33373826-0.281.1e-01Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_186717348 25.47 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
KNG1
kininogen 1
chr9_+_114323098 14.49 ENST00000259396.9
ORM1
orosomucoid 1
chr4_+_73404255 13.97 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
ALB
albumin
chr11_+_18266254 11.82 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
SAA1
serum amyloid A1
chr16_+_72054477 11.43 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr19_-_4540028 11.16 ENST00000306390.7
LRG1
leucine rich alpha-2-glycoprotein 1
chr3_+_186613052 11.00 ENST00000411641.7
ENST00000273784.5
AHSG
alpha 2-HS glycoprotein
chr16_+_72063226 10.13 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
HPR
haptoglobin-related protein
chr11_-_18236795 10.04 ENST00000278222.7
SAA4
serum amyloid A4, constitutive
chr3_-_149221811 8.34 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chr13_-_46105009 7.95 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr17_-_66229380 7.62 ENST00000205948.11
APOH
apolipoprotein H
chr2_-_21044063 7.60 ENST00000233242.5
APOB
apolipoprotein B
chr6_+_31927683 6.44 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr3_-_120682113 5.96 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chrX_+_139530730 5.92 ENST00000218099.7
F9
coagulation factor IX
chr1_+_196774813 5.87 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
CFHR3
complement factor H related 3
chr6_-_134950081 5.85 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
ALDH8A1
aldehyde dehydrogenase 8 family member A1
chr1_-_204213943 5.76 ENST00000308302.4
GOLT1A
golgi transport 1A
chr6_+_31927703 5.65 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
C2
ENSG00000244255.5
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr12_-_95996302 5.61 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr12_+_111034136 5.57 ENST00000261726.11
CUX2
cut like homeobox 2
chr3_-_194351290 5.48 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chrX_+_139530752 5.00 ENST00000394090.2
F9
coagulation factor IX
chr6_+_31927486 4.99 ENST00000442278.6
C2
complement C2
chr3_-_49689053 4.89 ENST00000449682.2
MST1
macrophage stimulating 1
chr9_+_128149447 4.86 ENST00000277480.7
ENST00000372998.1
LCN2
lipocalin 2
chr6_+_31927510 4.81 ENST00000447952.6
C2
complement C2
chr9_+_78297117 4.80 ENST00000376588.4
PSAT1
phosphoserine aminotransferase 1
chr22_-_30505650 4.77 ENST00000381982.3
ENST00000255858.12
SEC14L4
SEC14 like lipid binding 4
chr14_-_69797232 4.66 ENST00000216540.5
SLC10A1
solute carrier family 10 member 1
chr1_+_196888014 4.49 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
CFHR4
complement factor H related 4
chrX_+_47078380 4.36 ENST00000352078.8
RGN
regucalcin
chrX_+_47078434 4.28 ENST00000397180.6
RGN
regucalcin
chr9_+_78297143 4.25 ENST00000347159.6
PSAT1
phosphoserine aminotransferase 1
chr10_-_68332914 4.18 ENST00000358769.7
ENST00000495025.2
PBLD
phenazine biosynthesis like protein domain containing
chr11_+_76782250 4.10 ENST00000533752.1
ENST00000612930.1
TSKU
tsukushi, small leucine rich proteoglycan
chr8_-_120811988 4.06 ENST00000517992.2
SNTB1
syntrophin beta 1
chr10_-_68332878 3.99 ENST00000309049.8
PBLD
phenazine biosynthesis like protein domain containing
chr2_-_21043941 3.93 ENST00000399256.4
APOB
apolipoprotein B
chr8_-_6877928 3.18 ENST00000297439.4
DEFB1
defensin beta 1
chr4_-_110198650 3.00 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr21_-_34526850 2.97 ENST00000481448.5
ENST00000381132.6
RCAN1
regulator of calcineurin 1
chr4_-_110198579 2.82 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr20_+_380747 2.64 ENST00000217233.9
TRIB3
tribbles pseudokinase 3
chr6_+_131135408 2.61 ENST00000431975.7
ENST00000683794.1
AKAP7
A-kinase anchoring protein 7
chr12_+_7060676 2.54 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
C1S
complement C1s
chr3_-_190862688 2.52 ENST00000442080.6
GMNC
geminin coiled-coil domain containing
chr12_+_103930600 2.45 ENST00000680316.1
ENST00000679861.1
HSP90B1
heat shock protein 90 beta family member 1
chr8_+_96584920 2.44 ENST00000521590.5
SDC2
syndecan 2
chr19_+_2476118 2.44 ENST00000215631.9
ENST00000587345.1
GADD45B
growth arrest and DNA damage inducible beta
chr19_-_6670151 2.42 ENST00000675206.1
TNFSF14
TNF superfamily member 14
chr11_-_72793636 2.42 ENST00000538536.5
ENST00000543304.5
ENST00000540587.1
STARD10
StAR related lipid transfer domain containing 10
chr19_-_6670117 2.39 ENST00000245912.7
TNFSF14
TNF superfamily member 14
chr5_-_140633167 2.12 ENST00000302014.11
CD14
CD14 molecule
chr4_-_110198976 1.98 ENST00000506625.5
ELOVL6
ELOVL fatty acid elongase 6
chr21_-_36480060 1.94 ENST00000399137.5
CLDN14
claudin 14
chr20_+_381246 1.86 ENST00000449710.5
ENST00000422053.3
TRIB3
tribbles pseudokinase 3
chrX_+_23667461 1.86 ENST00000379341.9
ENST00000379331.3
PRDX4
peroxiredoxin 4
chr9_+_133534807 1.83 ENST00000393060.1
ADAMTSL2
ADAMTS like 2
chr18_+_74499861 1.82 ENST00000324301.12
CNDP2
carnosine dipeptidase 2
chr4_-_110199173 1.69 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr1_+_59296971 1.66 ENST00000371218.8
FGGY
FGGY carbohydrate kinase domain containing
chr21_-_36480117 1.58 ENST00000399135.6
CLDN14
claudin 14
chr18_+_74499939 1.51 ENST00000584768.5
CNDP2
carnosine dipeptidase 2
chr3_+_101849505 1.44 ENST00000326151.9
ENST00000326172.9
NFKBIZ
NFKB inhibitor zeta
chr6_-_132734692 1.38 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
VNN3
vanin 3
chr8_-_7018295 1.37 ENST00000327857.7
DEFA3
defensin alpha 3
chr18_-_28036585 1.35 ENST00000399380.7
CDH2
cadherin 2
chr19_+_57394183 1.34 ENST00000597410.1
ENSG00000268533.1
novel protein
chr9_+_113150991 1.32 ENST00000259392.8
SLC31A2
solute carrier family 31 member 2
chr9_+_83623048 1.32 ENST00000454393.5
IDNK
IDNK gluconokinase
chr5_+_159865080 1.31 ENST00000641205.1
ADRA1B
adrenoceptor alpha 1B
chr9_+_69145463 1.30 ENST00000636438.1
TJP2
tight junction protein 2
chr19_+_48756067 1.27 ENST00000222157.5
FGF21
fibroblast growth factor 21
chr17_+_49210387 1.17 ENST00000419580.6
ABI3
ABI family member 3
chr10_+_26697653 1.06 ENST00000376215.10
PDSS1
decaprenyl diphosphate synthase subunit 1
chr1_-_47190013 1.01 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr7_-_8236878 0.94 ENST00000401396.5
ENST00000317367.9
ICA1
islet cell autoantigen 1
chr5_+_36152077 0.84 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chr19_+_48755512 0.82 ENST00000593756.6
FGF21
fibroblast growth factor 21
chr10_-_14554141 0.82 ENST00000496330.5
FAM107B
family with sequence similarity 107 member B
chr7_-_138755892 0.82 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr11_-_72793592 0.80 ENST00000536377.5
ENST00000359373.9
STARD10
ARAP1
StAR related lipid transfer domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_64563063 0.73 ENST00000309683.11
ZNF680
zinc finger protein 680
chr14_+_44897268 0.69 ENST00000325192.8
ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chrX_-_74614612 0.62 ENST00000349225.2
ENST00000332687.11
RLIM
ring finger protein, LIM domain interacting
chr11_+_60056587 0.59 ENST00000395032.6
ENST00000358152.6
MS4A3
membrane spanning 4-domains A3
chr11_+_26188836 0.58 ENST00000672621.1
ANO3
anoctamin 3
chr14_-_80212169 0.57 ENST00000553968.1
DIO2
iodothyronine deiodinase 2
chr6_-_30742670 0.56 ENST00000376389.8
FLOT1
flotillin 1
chr4_+_70360751 0.56 ENST00000226460.5
SMR3A
submaxillary gland androgen regulated protein 3A
chrX_-_74925452 0.53 ENST00000055682.12
ENST00000616200.2
ENST00000642681.2
NEXMIF
neurite extension and migration factor
chr3_-_42264887 0.52 ENST00000334681.9
CCK
cholecystokinin
chr1_+_165895583 0.51 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr1_-_113887375 0.51 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2 like 15
chr5_-_36151853 0.50 ENST00000296603.5
LMBRD2
LMBR1 domain containing 2
chr3_+_178536205 0.49 ENST00000420517.6
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr11_+_60056653 0.49 ENST00000278865.8
MS4A3
membrane spanning 4-domains A3
chrX_-_41923547 0.49 ENST00000378163.7
CASK
calcium/calmodulin dependent serine protein kinase
chr14_+_39233908 0.46 ENST00000280082.4
MIA2
MIA SH3 domain ER export factor 2
chr6_-_30742486 0.45 ENST00000438162.5
ENST00000454845.1
FLOT1
flotillin 1
chr5_+_36151989 0.45 ENST00000274254.9
SKP2
S-phase kinase associated protein 2
chr9_+_107283256 0.44 ENST00000358015.8
RAD23B
RAD23 homolog B, nucleotide excision repair protein
chr15_+_23565755 0.44 ENST00000678440.1
ENST00000676568.1
MKRN3
makorin ring finger protein 3
chr19_+_54906140 0.43 ENST00000291890.9
ENST00000598576.5
ENST00000594765.5
ENST00000350790.9
ENST00000338835.9
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr1_-_1779976 0.41 ENST00000378625.5
NADK
NAD kinase
chr11_-_102798148 0.39 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr8_-_144060681 0.39 ENST00000618853.5
OPLAH
5-oxoprolinase, ATP-hydrolysing
chr9_+_128098304 0.38 ENST00000373064.9
SLC25A25
solute carrier family 25 member 25
chr3_+_178536407 0.33 ENST00000452583.6
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr1_+_165895564 0.32 ENST00000469256.6
UCK2
uridine-cytidine kinase 2
chr20_-_46363174 0.31 ENST00000372227.5
SLC35C2
solute carrier family 35 member C2
chr1_+_89843421 0.30 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 VRAC subunit D
chr11_+_55635113 0.29 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chr1_+_93179883 0.28 ENST00000343253.11
CCDC18
coiled-coil domain containing 18
chrX_+_110520312 0.27 ENST00000602699.1
TDGF1P3
teratocarcinoma-derived growth factor 1 pseudogene 3
chr5_-_146878595 0.26 ENST00000394409.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr19_+_44891206 0.25 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
TOMM40
translocase of outer mitochondrial membrane 40
chr7_-_13986498 0.24 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETV1
ETS variant transcription factor 1
chr1_-_153348825 0.24 ENST00000368739.3
ENST00000359650.10
PGLYRP4
peptidoglycan recognition protein 4
chr1_+_172420696 0.23 ENST00000460397.2
C1orf105
chromosome 1 open reading frame 105
chr17_+_7573722 0.22 ENST00000581384.5
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr11_-_35360050 0.21 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr4_+_70383123 0.21 ENST00000304915.8
SMR3B
submaxillary gland androgen regulated protein 3B
chr6_-_656963 0.20 ENST00000380907.2
HUS1B
HUS1 checkpoint clamp component B
chr11_-_60243103 0.19 ENST00000651255.1
MS4A4E
membrane spanning 4-domains A4E
chr18_-_55422290 0.19 ENST00000625925.2
TCF4
transcription factor 4
chr22_-_30471986 0.18 ENST00000401751.5
ENST00000402286.5
ENST00000403066.5
ENST00000215812.9
SEC14L3
SEC14 like lipid binding 3
chr3_+_96814791 0.18 ENST00000506569.1
EPHA6
EPH receptor A6
chr19_-_40465760 0.18 ENST00000643519.1
BLVRB
biliverdin reductase B
chr7_-_144259722 0.14 ENST00000493325.1
OR2A7
olfactory receptor family 2 subfamily A member 7
chr19_+_48993525 0.13 ENST00000601968.5
ENST00000596837.5
RUVBL2
RuvB like AAA ATPase 2
chr1_+_248038172 0.12 ENST00000366479.4
OR2L2
olfactory receptor family 2 subfamily L member 2
chr4_+_174918366 0.12 ENST00000502940.1
ENST00000502305.5
ADAM29
ADAM metallopeptidase domain 29
chr5_-_136365476 0.10 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
TRPC7
transient receptor potential cation channel subfamily C member 7
chr15_+_22080625 0.09 ENST00000614722.2
OR4M2
olfactory receptor family 4 subfamily M member 2
chr2_+_102104563 0.08 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr19_+_47035300 0.08 ENST00000439365.6
ENST00000594670.1
NPAS1
neuronal PAS domain protein 1
chr16_+_6019071 0.07 ENST00000547605.5
ENST00000553186.5
RBFOX1
RNA binding fox-1 homolog 1
chr6_+_18387326 0.06 ENST00000259939.4
RNF144B
ring finger protein 144B
chr18_-_55422241 0.06 ENST00000628636.2
TCF4
transcription factor 4
chr19_+_48993864 0.04 ENST00000595090.6
RUVBL2
RuvB like AAA ATPase 2
chr3_+_68006224 0.04 ENST00000496687.1
TAFA1
TAFA chemokine like family member 1
chr1_-_60073733 0.04 ENST00000450089.6
C1orf87
chromosome 1 open reading frame 87
chr7_-_108328635 0.04 ENST00000456431.5
NRCAM
neuronal cell adhesion molecule
chr5_+_126423176 0.02 ENST00000542322.5
ENST00000544396.5
GRAMD2B
GRAM domain containing 2B
chr12_+_64497968 0.01 ENST00000676593.1
ENST00000677093.1
TBK1
ENSG00000288665.1
TANK binding kinase 1
novel transcript

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
3.8 11.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.7 8.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
2.2 8.6 GO:1903633 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
2.0 7.9 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.5 9.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
1.4 44.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.3 11.5 GO:0006642 triglyceride mobilization(GO:0006642)
1.0 14.5 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
1.0 15.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.0 4.9 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.9 4.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.8 4.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 2.5 GO:0031247 actin rod assembly(GO:0031247)
0.8 5.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.7 9.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 5.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 3.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 6.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 2.4 GO:0008218 bioluminescence(GO:0008218)
0.3 2.1 GO:1904640 response to methionine(GO:1904640)
0.3 1.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.3 11.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 9.7 GO:0006825 copper ion transport(GO:0006825)
0.3 2.1 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 1.8 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.3 1.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.3 11.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 9.6 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.2 1.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 5.6 GO:0007614 short-term memory(GO:0007614)
0.2 0.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 3.2 GO:0032782 bile acid secretion(GO:0032782)
0.2 4.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 4.9 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.1 1.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 4.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 3.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 10.0 GO:0050918 positive chemotaxis(GO:0050918)
0.1 3.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.6 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.2 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.1 8.4 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1 2.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 3.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 2.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 1.1 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.5 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.8 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.4 11.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.9 39.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.6 3.2 GO:1990742 microvesicle(GO:1990742)
0.5 64.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 3.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 14.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 2.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 14.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 20.9 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 4.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0016600 flotillin complex(GO:0016600)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.0 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 4.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.0 GO:0030492 hemoglobin binding(GO:0030492)
2.2 8.6 GO:0004341 gluconolactonase activity(GO:0004341)
2.0 6.0 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
1.9 7.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.4 11.5 GO:0035473 lipase binding(GO:0035473)
0.8 8.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 5.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.8 3.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.7 9.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7 4.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.6 14.0 GO:0015643 toxic substance binding(GO:0015643)
0.6 3.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.4 1.7 GO:0019150 D-ribulokinase activity(GO:0019150)
0.4 21.9 GO:0042056 chemoattractant activity(GO:0042056)
0.4 5.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 41.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 3.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 13.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.8 GO:0050436 microfibril binding(GO:0050436)
0.3 2.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 1.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 4.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 9.1 GO:0008483 transaminase activity(GO:0008483)
0.1 11.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 32.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 2.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.8 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 7.6 GO:0016853 isomerase activity(GO:0016853)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.8 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 4.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 3.7 GO:0005506 iron ion binding(GO:0005506)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 25.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 13.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 12.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 12.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 11.0 PID BMP PATHWAY BMP receptor signaling
0.1 8.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 11.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 11.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 36.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.0 18.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 21.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 11.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 11.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 8.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 9.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 8.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 2.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 11.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.0 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.3 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)