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avrg: Illumina Body Map 2 (GSE30611)

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Results for CREB3L1_CREB3

Z-value: 1.67

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol Gene ID Gene Info
CREB3L1
ENSG00000157613.11 CREB3L1
CREB3
ENSG00000107175.12 CREB3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3L1hg38_v1_chr11_+_46295126_462951700.086.7e-01Click!
CREB3hg38_v1_chr9_+_35732649_35732685-0.029.2e-01Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_31948956 7.80 ENST00000483004.1
CFB
complement factor B
chr22_+_38468036 7.75 ENST00000409006.3
ENST00000216014.9
KDELR3
KDEL endoplasmic reticulum protein retention receptor 3
chr3_+_100492548 5.46 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr6_+_32024278 4.74 ENST00000647698.1
C4B
complement C4B (Chido blood group)
chr3_-_129121761 3.42 ENST00000476465.5
ENST00000393304.5
ENST00000315150.10
ENST00000615093.1
ENST00000393308.5
ENST00000393307.5
ENST00000393305.5
RAB43
RAB43, member RAS oncogene family
chr19_-_4670331 3.41 ENST00000262947.8
ENST00000599630.1
MYDGF
myeloid derived growth factor
chr8_-_63026179 3.24 ENST00000677919.1
GGH
gamma-glutamyl hydrolase
chr19_+_49527988 3.11 ENST00000270645.8
RCN3
reticulocalbin 3
chr2_-_88857582 2.99 ENST00000390237.2
IGKC
immunoglobulin kappa constant
chr9_+_99222258 2.96 ENST00000223641.5
SEC61B
SEC61 translocon subunit beta
chr7_-_73770258 2.76 ENST00000395145.3
CLDN3
claudin 3
chr16_-_68236069 2.74 ENST00000473183.7
ENST00000565858.5
ESRP2
epithelial splicing regulatory protein 2
chr4_+_25234003 2.73 ENST00000264864.8
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr3_+_37861926 2.53 ENST00000443503.6
CTDSPL
CTD small phosphatase like
chr7_+_94394886 2.45 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chrX_+_153794152 2.44 ENST00000370087.5
SSR4
signal sequence receptor subunit 4
chrX_+_153794635 2.43 ENST00000370086.8
ENST00000370085.3
SSR4
signal sequence receptor subunit 4
chr8_-_38269116 2.35 ENST00000529359.5
PLPP5
phospholipid phosphatase 5
chr8_-_38269157 2.28 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
PLPP5
phospholipid phosphatase 5
chr4_+_8592750 2.15 ENST00000315782.6
ENST00000360986.9
CPZ
carboxypeptidase Z
chr16_+_19113955 1.97 ENST00000381440.5
ENST00000564808.6
ENST00000568526.1
ITPRIPL2
ENSG00000261427.6
ITPRIP like 2
novel transcript
chr3_+_37861849 1.96 ENST00000273179.10
CTDSPL
CTD small phosphatase like
chr12_-_106247950 1.90 ENST00000378026.5
CKAP4
cytoskeleton associated protein 4
chr3_-_57597325 1.89 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ARF4
ADP ribosylation factor 4
chr1_+_119368773 1.85 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
HAO2
hydroxyacid oxidase 2
chr7_+_16753731 1.82 ENST00000262067.5
TSPAN13
tetraspanin 13
chr16_-_11742739 1.81 ENST00000356957.7
ENST00000283033.10
TXNDC11
thioredoxin domain containing 11
chr5_+_127517611 1.81 ENST00000296666.13
ENST00000442138.6
ENST00000512635.2
PRRC1
proline rich coiled-coil 1
chr3_-_49358320 1.80 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
GPX1
glutathione peroxidase 1
chr9_-_95317671 1.71 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FANCC
FA complementation group C
chrX_+_47582408 1.66 ENST00000456754.6
ENST00000218388.9
ENST00000377017.5
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr19_-_10231293 1.65 ENST00000646641.1
S1PR2
sphingosine-1-phosphate receptor 2
chr1_+_119368802 1.65 ENST00000361035.8
ENST00000419144.1
HAO2
HAO2-IT1
hydroxyacid oxidase 2
HAO2 intronic transcript 1
chr7_+_65873324 1.59 ENST00000434382.2
VKORC1L1
vitamin K epoxide reductase complex subunit 1 like 1
chr11_+_32091065 1.59 ENST00000054950.4
RCN1
reticulocalbin 1
chr3_+_123067016 1.59 ENST00000316218.12
PDIA5
protein disulfide isomerase family A member 5
chr17_+_28744002 1.58 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TRAF4
TNF receptor associated factor 4
chr1_+_162561504 1.56 ENST00000271469.7
ENST00000367926.8
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr5_+_69093943 1.56 ENST00000621204.4
SLC30A5
solute carrier family 30 member 5
chr5_+_134648772 1.55 ENST00000398844.7
ENST00000322887.8
SEC24A
SEC24 homolog A, COPII coat complex component
chr15_-_53759634 1.49 ENST00000557913.5
ENST00000360509.10
WDR72
WD repeat domain 72
chr2_+_182716227 1.47 ENST00000680258.1
ENST00000680667.1
ENST00000264065.12
ENST00000616986.5
ENST00000679884.1
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10
chr5_-_10761156 1.47 ENST00000432074.2
ENST00000230895.11
DAP
death associated protein
chr9_-_99221897 1.46 ENST00000476832.2
ALG2
ALG2 alpha-1,3/1,6-mannosyltransferase
chr12_+_106955890 1.46 ENST00000280756.9
TMEM263
transmembrane protein 263
chr19_-_48390847 1.42 ENST00000597017.5
KDELR1
KDEL endoplasmic reticulum protein retention receptor 1
chr2_-_69387188 1.40 ENST00000674507.1
ENST00000357308.9
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr12_-_48924919 1.38 ENST00000444214.6
FKBP11
FKBP prolyl isomerase 11
chr4_+_107825126 1.37 ENST00000503862.5
SGMS2
sphingomyelin synthase 2
chr12_-_104958268 1.33 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
SLC41A2
solute carrier family 41 member 2
chr9_+_111631300 1.31 ENST00000313525.4
DNAJC25
DnaJ heat shock protein family (Hsp40) member C25
chr5_+_95555085 1.28 ENST00000380009.9
ARSK
arylsulfatase family member K
chr16_+_56657924 1.28 ENST00000334350.7
MT1F
metallothionein 1F
chr12_+_56230652 1.26 ENST00000266980.8
ENST00000437277.1
SLC39A5
solute carrier family 39 member 5
chr20_-_17682060 1.26 ENST00000455029.3
RRBP1
ribosome binding protein 1
chr7_-_94004345 1.26 ENST00000222547.8
ENST00000433727.5
BET1
Bet1 golgi vesicular membrane trafficking protein
chr1_-_119140628 1.26 ENST00000369426.9
ENST00000235521.5
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr4_-_118836067 1.26 ENST00000280551.11
SEC24D
SEC24 homolog D, COPII coat complex component
chr19_+_38319807 1.25 ENST00000263372.5
KCNK6
potassium two pore domain channel subfamily K member 6
chr19_+_48965304 1.23 ENST00000331825.11
FTL
ferritin light chain
chr11_-_18322122 1.23 ENST00000349215.8
ENST00000396253.7
ENST00000438420.6
HPS5
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr4_-_82429386 1.22 ENST00000507721.5
HNRNPDL
heterogeneous nuclear ribonucleoprotein D like
chr11_-_119057185 1.21 ENST00000614668.4
ENST00000617285.5
HYOU1
hypoxia up-regulated 1
chr12_+_106955719 1.21 ENST00000548125.5
TMEM263
transmembrane protein 263
chr19_+_50476496 1.15 ENST00000597426.1
ENST00000376918.7
ENST00000334976.11
ENST00000598585.1
EMC10
ER membrane protein complex subunit 10
chr19_+_797392 1.15 ENST00000627714.2
ENST00000349038.8
ENST00000586481.5
PTBP1
polypyrimidine tract binding protein 1
chr17_+_42536226 1.14 ENST00000225927.7
NAGLU
N-acetyl-alpha-glucosaminidase
chr3_-_49358272 1.13 ENST00000419349.2
GPX1
glutathione peroxidase 1
chr19_+_797443 1.12 ENST00000356948.11
ENST00000394601.8
ENST00000589575.5
ENST00000587191.3
PTBP1
polypyrimidine tract binding protein 1
chr12_-_120201099 1.12 ENST00000551150.5
ENST00000313104.9
ENST00000547191.5
ENST00000546989.5
ENST00000392514.9
ENST00000228306.8
ENST00000550856.5
RPLP0
ribosomal protein lateral stalk subunit P0
chr3_-_4467241 1.11 ENST00000383843.9
ENST00000272902.10
ENST00000458465.6
ENST00000405420.2
SUMF1
sulfatase modifying factor 1
chr11_-_119101814 1.10 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
DPAGT1
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr3_-_57597443 1.09 ENST00000463880.1
ARF4
ADP ribosylation factor 4
chr8_-_70607654 1.08 ENST00000521425.5
TRAM1
translocation associated membrane protein 1
chr2_-_69387241 1.08 ENST00000361060.5
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr2_+_232697362 1.05 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GIGYF2
GRB10 interacting GYF protein 2
chr2_-_69387130 1.05 ENST00000674438.1
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr11_-_119057218 1.05 ENST00000652093.1
HYOU1
hypoxia up-regulated 1
chr7_-_94004372 1.04 ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr5_-_39424966 1.04 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB2
DAB adaptor protein 2
chr10_-_96586975 1.04 ENST00000371142.9
TM9SF3
transmembrane 9 superfamily member 3
chr5_-_39425187 1.00 ENST00000545653.5
DAB2
DAB adaptor protein 2
chr2_+_27032938 1.00 ENST00000238788.14
ENST00000404032.7
TMEM214
transmembrane protein 214
chr20_+_33007695 1.00 ENST00000170150.4
BPIFB2
BPI fold containing family B member 2
chr1_-_155173245 0.98 ENST00000497317.5
ENST00000482246.5
ENST00000295682.6
KRTCAP2
keratinocyte associated protein 2
chr20_-_17682234 0.96 ENST00000377813.6
ENST00000377807.6
ENST00000360807.8
ENST00000398782.2
RRBP1
ribosome binding protein 1
chr8_+_22565967 0.95 ENST00000522721.1
SORBS3
sorbin and SH3 domain containing 3
chr12_+_56158343 0.95 ENST00000548580.5
ENST00000293422.9
ENST00000348108.8
ENST00000549017.5
ENST00000549566.5
ENST00000550697.6
ENST00000536128.5
ENST00000547649.5
ENST00000547408.5
ENST00000551589.5
ENST00000549392.5
ENST00000548400.5
ENST00000548293.5
MYL6
myosin light chain 6
chr11_-_119057105 0.95 ENST00000534233.5
ENST00000614711.4
ENST00000530467.5
ENST00000621959.4
ENST00000532519.6
ENST00000532421.5
ENST00000610597.1
ENST00000612687.4
HYOU1
hypoxia up-regulated 1
chr17_+_42536510 0.94 ENST00000585572.1
ENST00000586516.5
ENST00000591587.1
ENSG00000266929.1
NAGLU
novel transcript
N-acetyl-alpha-glucosaminidase
chr19_+_5681140 0.94 ENST00000579559.1
ENST00000577222.5
HSD11B1L
RPL36
hydroxysteroid 11-beta dehydrogenase 1 like
ribosomal protein L36
chr5_-_172283743 0.93 ENST00000393792.3
UBTD2
ubiquitin domain containing 2
chr16_+_56657999 0.92 ENST00000568475.1
MT1F
metallothionein 1F
chr5_+_69093980 0.92 ENST00000380860.8
ENST00000396591.8
ENST00000504103.5
ENST00000502979.1
SLC30A5
solute carrier family 30 member 5
chr5_-_39424859 0.91 ENST00000503513.5
DAB2
DAB adaptor protein 2
chr3_-_49358340 0.89 ENST00000419783.3
GPX1
glutathione peroxidase 1
chr8_+_22565655 0.89 ENST00000523965.5
SORBS3
sorbin and SH3 domain containing 3
chr6_+_151240368 0.89 ENST00000253332.5
AKAP12
A-kinase anchoring protein 12
chr2_+_10044175 0.88 ENST00000440320.5
ENST00000535335.1
KLF11
Kruppel like factor 11
chr17_+_28744034 0.88 ENST00000444415.7
ENST00000262396.10
TRAF4
TNF receptor associated factor 4
chr3_+_186974957 0.87 ENST00000438590.5
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr9_-_124941054 0.85 ENST00000373555.9
GOLGA1
golgin A1
chr12_+_106955828 0.83 ENST00000547242.5
ENST00000551489.5
ENST00000550344.5
TMEM263
transmembrane protein 263
chr22_-_23838987 0.83 ENST00000318109.12
ENST00000404056.1
ENST00000406855.7
ENST00000476077.1
DERL3
derlin 3
chr14_+_49620750 0.82 ENST00000305386.4
MGAT2
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr4_+_128061500 0.80 ENST00000649983.1
ENST00000648358.1
ENST00000650359.1
LARP1B
La ribonucleoprotein 1B
chr11_-_18322178 0.79 ENST00000531848.1
HPS5
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr12_-_55927103 0.79 ENST00000398213.4
PYM1
PYM homolog 1, exon junction complex associated factor
chr9_+_98056694 0.77 ENST00000210444.6
NANS
N-acetylneuraminate synthase
chr17_+_7252024 0.77 ENST00000573513.5
ENST00000354429.6
ENST00000574255.5
ENST00000356683.6
ENST00000396627.6
ELP5
elongator acetyltransferase complex subunit 5
chr11_+_809961 0.76 ENST00000321153.9
ENST00000530797.5
RPLP2
ribosomal protein lateral stalk subunit P2
chr11_+_47408582 0.76 ENST00000531974.5
ENST00000362021.9
ENST00000531419.5
ENST00000531865.5
ENST00000354884.8
SLC39A13
solute carrier family 39 member 13
chr12_-_56315952 0.76 ENST00000273308.9
CNPY2
canopy FGF signaling regulator 2
chr2_-_43595963 0.75 ENST00000405006.8
THADA
THADA armadillo repeat containing
chr19_+_49528290 0.74 ENST00000597801.1
RCN3
reticulocalbin 3
chr6_-_7313146 0.74 ENST00000489567.5
ENST00000479365.5
ENST00000462112.1
ENST00000397511.6
ENST00000244763.9
ENST00000474597.5
ENST00000650389.1
SSR1
signal sequence receptor subunit 1
chr19_-_46413548 0.74 ENST00000307522.5
CCDC8
coiled-coil domain containing 8
chr11_-_119056850 0.73 ENST00000530473.5
HYOU1
hypoxia up-regulated 1
chr9_-_108934060 0.73 ENST00000675406.1
ENST00000676237.1
ENST00000675825.1
ENST00000675052.1
ENST00000674535.1
ENST00000674938.1
ENST00000374647.10
ELP1
elongator acetyltransferase complex subunit 1
chr4_-_121072519 0.73 ENST00000379692.9
NDNF
neuron derived neurotrophic factor
chr3_-_126357399 0.72 ENST00000296233.4
KLF15
Kruppel like factor 15
chr8_+_63168597 0.71 ENST00000539294.6
ENST00000621957.4
ENST00000517371.5
ENST00000621413.4
ENST00000612880.4
YTHDF3
YTH N6-methyladenosine RNA binding protein 3
chr2_+_197500371 0.70 ENST00000409468.1
ENST00000233893.10
HSPE1
heat shock protein family E (Hsp10) member 1
chr11_-_59615673 0.70 ENST00000263847.6
OSBP
oxysterol binding protein
chr6_-_89352706 0.70 ENST00000435041.3
UBE2J1
ubiquitin conjugating enzyme E2 J1
chr6_-_73521783 0.68 ENST00000331523.7
ENST00000356303.7
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr4_+_140524179 0.67 ENST00000507667.1
ELMOD2
ELMO domain containing 2
chr12_-_50222694 0.67 ENST00000552783.5
LIMA1
LIM domain and actin binding 1
chr8_+_22565236 0.67 ENST00000523900.5
SORBS3
sorbin and SH3 domain containing 3
chr2_-_241315180 0.67 ENST00000441124.5
ENST00000391976.6
HDLBP
high density lipoprotein binding protein
chr5_+_66144288 0.65 ENST00000334121.11
SREK1
splicing regulatory glutamic acid and lysine rich protein 1
chr6_+_116370938 0.65 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
DSE
dermatan sulfate epimerase
chr2_+_171999937 0.65 ENST00000315796.5
METAP1D
methionyl aminopeptidase type 1D, mitochondrial
chr12_-_50222348 0.64 ENST00000552823.5
ENST00000552909.5
LIMA1
LIM domain and actin binding 1
chr3_-_190862688 0.64 ENST00000442080.6
GMNC
geminin coiled-coil domain containing
chr6_-_109381739 0.64 ENST00000504373.2
CD164
CD164 molecule
chr5_+_177303768 0.63 ENST00000303204.9
ENST00000503216.5
PRELID1
PRELI domain containing 1
chr12_-_113471851 0.63 ENST00000261731.4
LHX5
LIM homeobox 5
chr1_-_206772484 0.62 ENST00000423557.1
IL10
interleukin 10
chr11_-_62573846 0.62 ENST00000329251.5
EEF1G
eukaryotic translation elongation factor 1 gamma
chr1_-_153967621 0.62 ENST00000413622.5
ENST00000310483.10
SLC39A1
solute carrier family 39 member 1
chr3_-_119240870 0.61 ENST00000467604.5
ENST00000393765.7
ENST00000491906.5
ENST00000475803.5
ENST00000479150.5
ENST00000470111.5
ENST00000459820.5
ENST00000459778.5
ENST00000359213.7
B4GALT4
beta-1,4-galactosyltransferase 4
chr20_-_62475983 0.60 ENST00000252997.3
GATA5
GATA binding protein 5
chr3_+_25782914 0.60 ENST00000452098.1
OXSM
3-oxoacyl-ACP synthase, mitochondrial
chr7_-_100573865 0.59 ENST00000622764.3
SAP25
Sin3A associated protein 25
chr16_+_56608577 0.59 ENST00000245185.6
ENST00000561491.1
MT2A
metallothionein 2A
chr21_-_42879516 0.59 ENST00000330317.6
ENST00000398208.3
WDR4
WD repeat domain 4
chr12_-_56315890 0.59 ENST00000551286.1
ENST00000549318.5
CNPY2
ENSG00000144785.8
canopy FGF signaling regulator 2
novel protein
chr2_-_43595980 0.58 ENST00000403856.1
ENST00000404790.5
ENST00000405975.7
THADA
THADA armadillo repeat containing
chr10_+_87863595 0.57 ENST00000371953.8
PTEN
phosphatase and tensin homolog
chr6_+_151239951 0.57 ENST00000402676.7
AKAP12
A-kinase anchoring protein 12
chr11_-_119057024 0.56 ENST00000526656.5
HYOU1
hypoxia up-regulated 1
chr5_+_66144204 0.56 ENST00000612404.4
SREK1
splicing regulatory glutamic acid and lysine rich protein 1
chr16_-_54286763 0.56 ENST00000329734.4
IRX3
iroquois homeobox 3
chr8_+_63168553 0.55 ENST00000617200.1
ENST00000623280.3
YTHDF3
YTH N6-methyladenosine RNA binding protein 3
chr16_-_82011444 0.55 ENST00000328945.7
ENST00000532128.5
SDR42E1
short chain dehydrogenase/reductase family 42E, member 1
chr14_-_34875348 0.54 ENST00000360310.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr12_-_56316002 0.53 ENST00000547423.5
ENST00000548360.1
ENST00000551475.5
ENSG00000144785.8
CNPY2
novel protein
canopy FGF signaling regulator 2
chr1_+_32180044 0.53 ENST00000373609.1
TXLNA
taxilin alpha
chr2_+_191678122 0.53 ENST00000425611.9
ENST00000410026.7
NABP1
nucleic acid binding protein 1
chr11_-_119057169 0.52 ENST00000527038.6
HYOU1
hypoxia up-regulated 1
chr18_-_49492305 0.51 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
RPL17
RPL17-C18orf32
ribosomal protein L17
RPL17-C18orf32 readthrough
chr14_-_34874887 0.50 ENST00000382422.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr1_+_59814939 0.50 ENST00000371208.5
HOOK1
hook microtubule tethering protein 1
chrX_+_154398890 0.50 ENST00000406022.6
RPL10
ribosomal protein L10
chr5_-_132227472 0.49 ENST00000428369.6
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr6_+_151452447 0.49 ENST00000367294.4
ARMT1
acidic residue methyltransferase 1
chr15_+_43792305 0.48 ENST00000249786.9
ENST00000409960.6
ENST00000409646.5
ENST00000339624.9
ENST00000409291.5
ENST00000402131.5
ENST00000403425.5
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr17_-_341417 0.47 ENST00000575634.5
RPH3AL
rabphilin 3A like (without C2 domains)
chr22_-_27996239 0.47 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr11_-_14499833 0.46 ENST00000249923.7
ENST00000529866.5
COPB1
COPI coat complex subunit beta 1
chr17_-_68955332 0.45 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ABCA8
ATP binding cassette subfamily A member 8
chr7_-_101217569 0.45 ENST00000223127.8
PLOD3
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr11_-_62832033 0.45 ENST00000377897.8
ENST00000394690.5
ENST00000294179.8
STX5
syntaxin 5
chr17_+_7252268 0.44 ENST00000396628.6
ENST00000574993.5
ENST00000573657.5
ELP5
elongator acetyltransferase complex subunit 5
chr1_+_52602347 0.44 ENST00000361314.5
GPX7
glutathione peroxidase 7
chr14_+_103529208 0.44 ENST00000299202.4
TRMT61A
tRNA methyltransferase 61A
chr3_-_156555135 0.44 ENST00000467789.5
SSR3
signal sequence receptor subunit 3
chr4_+_140524147 0.44 ENST00000511887.6
ENST00000323570.8
ELMOD2
ELMO domain containing 2
chr18_+_59139864 0.43 ENST00000509791.7
ENST00000587834.6
ENST00000588875.2
SEC11C
SEC11 homolog C, signal peptidase complex subunit
chr6_-_137494387 0.43 ENST00000367734.4
OLIG3
oligodendrocyte transcription factor 3
chr1_+_32179665 0.42 ENST00000373610.8
TXLNA
taxilin alpha
chr9_-_108933927 0.42 ENST00000676416.1
ENST00000537196.1
ELP1
elongator acetyltransferase complex subunit 1
chr11_+_3797819 0.41 ENST00000396986.6
ENST00000300730.10
ENST00000396993.8
ENST00000532523.5
ENST00000459679.5
ENST00000464229.5
ENST00000464261.5
ENST00000490830.5
ENST00000464906.6
ENST00000464441.5
PGAP2
post-GPI attachment to proteins 2
chr17_+_50373214 0.41 ENST00000393271.6
ENST00000338165.9
ENST00000511519.6
EME1
essential meiotic structure-specific endonuclease 1
chr5_-_90529511 0.41 ENST00000500869.6
ENST00000315948.11
ENST00000509384.5
LYSMD3
LysM domain containing 3
chr11_-_14499803 0.40 ENST00000439561.7
ENST00000534234.5
COPB1
COPI coat complex subunit beta 1
chr12_-_55927865 0.40 ENST00000454792.2
ENST00000408946.7
PYM1
PYM homolog 1, exon junction complex associated factor
chr1_-_11805949 0.39 ENST00000376590.9
MTHFR
methylenetetrahydrofolate reductase
chr9_-_127715602 0.38 ENST00000456267.5
ENST00000414832.2
PTRH1
peptidyl-tRNA hydrolase 1 homolog
chr7_+_151232464 0.38 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
CHPF2
chondroitin polymerizing factor 2
chr3_-_139389604 0.38 ENST00000515006.5
ENST00000510181.6
ENST00000333188.10
ENST00000513274.5
ENST00000514508.2
ENST00000503326.6
ENST00000507777.6
ENST00000512242.6
ENST00000512153.5
ENST00000512309.2
COPB2
COPI coat complex subunit beta 2
chr19_+_48954850 0.38 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BAX
BCL2 associated X, apoptosis regulator
chr13_-_51453015 0.38 ENST00000442263.4
ENST00000311234.9
INTS6
integrator complex subunit 6
chrX_-_10576901 0.38 ENST00000380779.5
MID1
midline 1
chr19_-_45584810 0.37 ENST00000323060.3
OPA3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr10_-_88583304 0.37 ENST00000331772.9
RNLS
renalase, FAD dependent amine oxidase
chr19_-_55325316 0.37 ENST00000591570.5
ENST00000326652.9
TMEM150B
transmembrane protein 150B
chr16_+_2520430 0.37 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr1_+_173477324 0.37 ENST00000340385.6
PRDX6
peroxiredoxin 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1902905 positive regulation of fibril organization(GO:1902905)
1.1 3.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
1.1 3.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.8 9.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 3.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 5.0 GO:1903381 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.6 3.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 7.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 4.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 1.3 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3 1.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 5.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 2.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.6 GO:0071650 negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.2 3.4 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.2 0.6 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 2.5 GO:0006824 cobalt ion transport(GO:0006824)
0.2 3.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 1.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.5 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.6 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 2.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.9 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 1.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:1902512 B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 1.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 1.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.6 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.6 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.6 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 2.1 GO:0046548 retinal rod cell development(GO:0046548)
0.1 2.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.4 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414) homologous recombination-dependent replication fork processing(GO:1990426)
0.1 2.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.3 GO:0010260 organ senescence(GO:0010260)
0.1 1.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 4.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 1.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.3 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 2.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 6.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.8 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 4.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.2 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 1.6 GO:0050779 RNA destabilization(GO:0050779)
0.0 0.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 3.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 3.4 GO:0007032 endosome organization(GO:0007032)
0.0 3.4 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0042908 xenobiotic transport(GO:0042908)
0.0 1.0 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 2.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 3.5 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 2.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.4 GO:1902074 response to salt(GO:1902074)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 1.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.7 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.7 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 2.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0051036 regulation of endosome size(GO:0051036)
0.0 1.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.8 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.8 2.4 GO:0005584 collagen type I trimer(GO:0005584)
0.5 2.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 3.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 1.0 GO:0016590 ACF complex(GO:0016590)
0.3 6.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 1.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3 4.2 GO:0097413 Lewy body(GO:0097413)
0.2 1.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.7 GO:1990393 3M complex(GO:1990393)
0.1 1.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 2.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.9 GO:0042599 lamellar body(GO:0042599)
0.1 15.6 GO:0072562 blood microparticle(GO:0072562)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 3.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 4.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 16.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 3.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 3.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.9 9.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.9 3.5 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.4 1.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 2.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 12.5 GO:0001848 complement binding(GO:0001848)
0.3 3.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 1.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.6 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2 1.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 4.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.6 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.2 0.8 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.6 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.9 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.7 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 2.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 4.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 3.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 3.2 GO:0008242 omega peptidase activity(GO:0008242)
0.1 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 3.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 1.9 GO:0070513 death domain binding(GO:0070513)
0.1 0.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 1.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 2.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.2 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0047025 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 2.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 3.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0008434 calcitriol receptor activity(GO:0008434) lithocholic acid receptor activity(GO:0038186) calcitriol binding(GO:1902098) lithocholic acid binding(GO:1902121)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 5.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 3.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.8 GO:0000149 SNARE binding(GO:0000149)
0.0 2.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.0 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 3.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 14.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 4.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 14.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 2.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 2.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)