ISMARA results: ESR1

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avrg: Illumina Body Map 2 (GSE30611)

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Results for ESR1

Z-value: 3.47

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Transcription factors associated with ESR1

Gene Symbol	Gene ID	Gene Info
ESR1 Ensembl NCBI GeneCards UniProt	ENSG00000091831.24	ESR1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ESR1	hg38_v1_chr6_+_151809105_151809139	0.25	1.6e-01	Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr22_+_22686724 Show fit	19.35	ENST00000390305.2	IGLV3-25 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-25
chr22_+_22758698 Show fit	15.61	ENST00000390312.2	IGLV2-14 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr22_+_22409755 Show fit	10.19	ENST00000390299.2	IGLV1-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-40
chr22_+_22792485 Show fit	9.91	ENST00000390314.2	IGLV2-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr22_+_22369601 Show fit	9.81	ENST00000390295.3	IGLV7-46 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 7-46
chr14_-_105588322 Show fit	9.54	ENST00000497872.4 ENST00000390539.2	IGHA2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_22880706 Show fit	9.26	ENST00000390319.2	IGLV3-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-1
chr2_-_88947820 Show fit	9.11	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr22_+_22380766 Show fit	9.00	ENST00000390297.3	IGLV1-44 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-44
chr2_-_89100352 Show fit	8.88	ENST00000479981.1	IGKV1-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr22_+_22195753 Show fit	8.80	ENST00000390285.4	IGLV6-57 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 6-57
chr2_-_89010515 Show fit	7.98	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr22_+_22322452 Show fit	7.88	ENST00000390290.3	IGLV1-51 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-51
chr22_+_22357739 Show fit	7.87	ENST00000390294.2	IGLV1-47 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-47
chr2_-_89213917 Show fit	7.81	ENST00000498435.1	IGKV1-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr2_-_89268506 Show fit	7.67	ENST00000473726.1	IGKV1-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr22_+_22906342 Show fit	7.27	ENST00000390325.2	IGLC3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr2_-_89117844 Show fit	7.06	ENST00000490686.1	IGKV1-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr22_+_22395005 Show fit	6.98	ENST00000390298.2	IGLV7-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 7-43
chr2_-_88966767 Show fit	6.93	ENST00000464162.1	IGKV1-6 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-6
chr22_+_22697789 Show fit	6.50	ENST00000390306.2	IGLV2-23 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-23
chr22_+_22895368 Show fit	6.49	ENST00000390321.2	IGLC1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 1
chr14_-_105708627 Show fit	6.40	ENST00000641837.1 ENST00000390547.3	IGHA1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 1
chr2_-_88992903 Show fit	6.29	ENST00000495489.1	IGKV1-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr22_+_22822658 Show fit	6.12	ENST00000620395.2	IGLV2-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr22_+_22900976 Show fit	5.96	ENST00000390323.2	IGLC2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 2
chr2_+_89862438 Show fit	5.87	ENST00000448155.2	IGKV1D-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr14_-_106360320 Show fit	5.78	ENST00000390615.2	IGHV3-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr14_-_106269133 Show fit	5.67	ENST00000390609.3	IGHV3-23 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-23
chr14_-_106762576 Show fit	5.65	ENST00000624687.1	IGHV1-69D Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-69D
chr22_+_22030934 Show fit	5.52	ENST00000390282.2	IGLV4-69 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-69
chr8_+_11494367 Show fit	5.28	ENST00000259089.9 ENST00000529894.1	BLK Ensembl NCBI GeneCards UniProt Show fit	BLK proto-oncogene, Src family tyrosine kinase
chr2_-_88979016 Show fit	5.21	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr2_+_90154073 Show fit	5.12	ENST00000611391.1	IGKV1D-13 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr14_-_106579223 Show fit	5.07	ENST00000390626.2	IGHV5-51 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 5-51
chr22_+_22327298 Show fit	4.97	ENST00000390291.2	IGLV1-50 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-50 (non-functional)
chr22_+_22668286 Show fit	4.93	ENST00000390304.2	IGLV3-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-27
chr17_-_35880350 Show fit	4.85	ENST00000605140.6 ENST00000651122.1 ENST00000603197.6	CCL5 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 5
chr19_-_7732160 Show fit	4.75	ENST00000676742.1 ENST00000678118.1 ENST00000328853.10	CLEC4G Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 4 member G
chr22_+_22343185 Show fit	4.69	ENST00000427632.2	IGLV9-49 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 9-49
chr17_+_36064265 Show fit	4.50	ENST00000616054.2	CCL18 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 18
chr14_-_106639589 Show fit	4.42	ENST00000390630.3	IGHV4-61 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-61
chr17_-_3691748 Show fit	4.31	ENST00000552723.1	P2RX5 Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2X 5
chr14_-_94390667 Show fit	4.22	ENST00000557492.5 ENST00000355814.8 ENST00000437397.5 ENST00000448921.5 ENST00000393088.8	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr19_-_10334723 Show fit	4.13	ENST00000592945.1	ICAM3 Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr2_+_230225718 Show fit	4.10	ENST00000420434.7 ENST00000392045.8 ENST00000417495.7 ENST00000343805.10	SP140 Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein
chr15_-_22160868 Show fit	3.98	ENST00000604066.1	IGHV1OR15-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr19_+_49335396 Show fit	3.97	ENST00000598095.5 ENST00000426897.6 ENST00000323906.9 ENST00000535669.6 ENST00000597602.1 ENST00000595660.1	CD37 Ensembl NCBI GeneCards UniProt Show fit	CD37 molecule
chr14_-_94390650 Show fit	3.97	ENST00000449399.7 ENST00000404814.8	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr15_+_32718476 Show fit	3.94	ENST00000652365.1	GREM1 Ensembl NCBI GeneCards UniProt Show fit	gremlin 1, DAN family BMP antagonist
chr2_+_90038848 Show fit	3.90	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr14_-_94390614 Show fit	3.83	ENST00000553327.5 ENST00000556955.5 ENST00000557118.5 ENST00000440909.5	SERPINA1 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 1
chr1_+_206897435 Show fit	3.74	ENST00000391929.7 ENST00000294984.7 ENST00000611909.4 ENST00000367093.3	IL24 Ensembl NCBI GeneCards UniProt Show fit	interleukin 24
chr14_-_106005574 Show fit	3.48	ENST00000390595.3	IGHV1-3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-3
chr22_+_22098683 Show fit	3.46	ENST00000390283.2	IGLV8-61 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 8-61
chr11_+_67404077 Show fit	3.35	ENST00000542590.2 ENST00000312390.9	TBC1D10C Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10C
chr2_-_89297785 Show fit	3.33	ENST00000465170.1	IGKV1-37 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chr6_-_2903300 Show fit	3.13	ENST00000380698.5	SERPINB9 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 9
chr22_+_22904850 Show fit	3.06	ENST00000390324.2	IGLJ3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 3
chr22_-_23754376 Show fit	3.03	ENST00000398465.3 ENST00000248948.4	VPREB3 Ensembl NCBI GeneCards UniProt Show fit	V-set pre-B cell surrogate light chain 3
chr16_+_30183595 Show fit	2.97	ENST00000219150.10 ENST00000570045.5 ENST00000565497.5 ENST00000570244.5	CORO1A Ensembl NCBI GeneCards UniProt Show fit	coronin 1A
chr14_+_100019375 Show fit	2.87	ENST00000544450.6	EVL Ensembl NCBI GeneCards UniProt Show fit	Enah/Vasp-like
chr9_-_120926752 Show fit	2.85	ENST00000373887.8	TRAF1 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 1
chr6_-_30686624 Show fit	2.84	ENST00000274853.8	PPP1R18 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 18
chr19_+_544034 Show fit	2.82	ENST00000592501.5 ENST00000264553.6	GZMM Ensembl NCBI GeneCards UniProt Show fit	granzyme M
chr2_+_118942188 Show fit	2.80	ENST00000327097.5	MARCO Ensembl NCBI GeneCards UniProt Show fit	macrophage receptor with collagenous structure
chr3_+_46979659 Show fit	2.75	ENST00000450053.8	NBEAL2 Ensembl NCBI GeneCards UniProt Show fit	neurobeachin like 2
chr3_+_186930518 Show fit	2.75	ENST00000169298.8 ENST00000457772.6 ENST00000455441.5 ENST00000427315.5	ST6GAL1 Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr15_+_88639009 Show fit	2.67	ENST00000306072.10	ISG20 Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr3_+_186930759 Show fit	2.66	ENST00000677292.1 ENST00000458216.5	ST6GAL1 Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr5_-_67196791 Show fit	2.63	ENST00000256447.5	CD180 Ensembl NCBI GeneCards UniProt Show fit	CD180 molecule
chr19_+_18173804 Show fit	2.62	ENST00000407280.4	IFI30 Ensembl NCBI GeneCards UniProt Show fit	IFI30 lysosomal thiol reductase
chr4_-_154590735 Show fit	2.61	ENST00000403106.8 ENST00000622532.1 ENST00000651975.1	FGA Ensembl NCBI GeneCards UniProt Show fit	fibrinogen alpha chain
chr11_+_67403887 Show fit	2.57	ENST00000526387.5	TBC1D10C Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10C
chr1_+_161707244 Show fit	2.55	ENST00000349527.8 ENST00000294796.8 ENST00000309691.10 ENST00000367953.7 ENST00000367950.2	FCRLA Ensembl NCBI GeneCards UniProt Show fit	Fc receptor like A
chr2_+_230225756 Show fit	2.54	ENST00000373645.3	SP140 Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein
chr6_+_37005630 Show fit	2.51	ENST00000274963.13	FGD2 Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 2
chr2_+_89985922 Show fit	2.47	ENST00000390268.2	IGKV2D-26 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 2D-26
chr6_+_35297809 Show fit	2.44	ENST00000316637.7	DEF6 Ensembl NCBI GeneCards UniProt Show fit	DEF6 guanine nucleotide exchange factor
chr19_-_7747511 Show fit	2.41	ENST00000593660.5 ENST00000204801.12 ENST00000315591.12 ENST00000354397.10 ENST00000394161.9 ENST00000593821.5 ENST00000602261.5 ENST00000601256.1 ENST00000601951.5 ENST00000315599.12	CD209 Ensembl NCBI GeneCards UniProt Show fit	CD209 molecule
chr15_+_81196871 Show fit	2.40	ENST00000559383.5 ENST00000394660.6 ENST00000683961.1	IL16 Ensembl NCBI GeneCards UniProt Show fit	interleukin 16
chr17_+_50634845 Show fit	2.38	ENST00000427699.5 ENST00000285238.13	ABCC3 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 3
chr6_-_73452253 Show fit	2.35	ENST00000370318.5 ENST00000370315.4	CGAS Ensembl NCBI GeneCards UniProt Show fit	cyclic GMP-AMP synthase
chr3_-_183555696 Show fit	2.34	ENST00000341319.8	KLHL6 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 6
chr12_-_14843517 Show fit	2.33	ENST00000228936.6	ART4 Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr19_-_3606849 Show fit	2.32	ENST00000375190.10	TBXA2R Ensembl NCBI GeneCards UniProt Show fit	thromboxane A2 receptor
chr15_+_80933358 Show fit	2.22	ENST00000560027.1	CEMIP Ensembl NCBI GeneCards UniProt Show fit	cell migration inducing hyaluronidase 1
chr6_+_31494881 Show fit	2.19	ENST00000538442.5	MICB Ensembl NCBI GeneCards UniProt Show fit	MHC class I polypeptide-related sequence B
chr2_+_218323148 Show fit	2.19	ENST00000258362.7	PNKD Ensembl NCBI GeneCards UniProt Show fit	PNKD metallo-beta-lactamase domain containing
chr15_+_88638947 Show fit	2.16	ENST00000559876.2	ISG20 Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20
chr19_+_50415799 Show fit	2.16	ENST00000599632.1	ENSG00000142539.9 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr17_-_31318818 Show fit	2.09	ENST00000578584.5	ENSG00000265118.5 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr5_+_40679907 Show fit	2.08	ENST00000302472.4	PTGER4 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 4
chr19_-_4540028 Show fit	2.07	ENST00000306390.7	LRG1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich alpha-2-glycoprotein 1
chr1_-_111427731 Show fit	2.07	ENST00000369732.4	OVGP1 Ensembl NCBI GeneCards UniProt Show fit	oviductal glycoprotein 1
chr7_+_2632029 Show fit	2.05	ENST00000407643.5	TTYH3 Ensembl NCBI GeneCards UniProt Show fit	tweety family member 3
chr11_+_67289283 Show fit	2.02	ENST00000511455.7	ANKRD13D Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 13D
chr15_+_32717994 Show fit	1.97	ENST00000560677.5 ENST00000560830.1 ENST00000651154.1	GREM1 Ensembl NCBI GeneCards UniProt Show fit	gremlin 1, DAN family BMP antagonist
chr22_+_22747383 Show fit	1.96	ENST00000390311.3	IGLV3-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-16
chr1_+_9651723 Show fit	1.96	ENST00000377346.9 ENST00000536656.5 ENST00000628140.2	PIK3CD Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr1_+_196774813 Show fit	1.96	ENST00000471440.6 ENST00000391985.7 ENST00000617219.1 ENST00000367425.9	CFHR3 Ensembl NCBI GeneCards UniProt Show fit	complement factor H related 3
chr5_-_140633167 Show fit	1.95	ENST00000302014.11	CD14 Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr11_+_47248885 Show fit	1.94	ENST00000395397.7 ENST00000405576.5	NR1H3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 3
chr20_+_63736651 Show fit	1.93	ENST00000487026.5 ENST00000309546.8 ENST00000480139.5	LIME1 Ensembl NCBI GeneCards UniProt Show fit	Lck interacting transmembrane adaptor 1
chr1_+_161707222 Show fit	1.92	ENST00000236938.12	FCRLA Ensembl NCBI GeneCards UniProt Show fit	Fc receptor like A
chr22_+_39456996 Show fit	1.92	ENST00000341184.7	MGAT3 Ensembl NCBI GeneCards UniProt Show fit	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
chr8_-_21913671 Show fit	1.91	ENST00000523932.1 ENST00000276420.9	DOK2 Ensembl NCBI GeneCards UniProt Show fit	docking protein 2
chr2_+_118942290 Show fit	1.87	ENST00000412481.1	MARCO Ensembl NCBI GeneCards UniProt Show fit	macrophage receptor with collagenous structure
chr3_-_50303565 Show fit	1.86	ENST00000266031.8 ENST00000395143.6 ENST00000457214.6 ENST00000447605.2 ENST00000395144.7 ENST00000418723.1	HYAL1 Ensembl NCBI GeneCards UniProt Show fit	hyaluronidase 1
chr1_+_26021768 Show fit	1.86	ENST00000374280.4	EXTL1 Ensembl NCBI GeneCards UniProt Show fit	exostosin like glycosyltransferase 1
chr16_-_74700845 Show fit	1.85	ENST00000308807.12 ENST00000573267.1	MLKL Ensembl NCBI GeneCards UniProt Show fit	mixed lineage kinase domain like pseudokinase
chr19_+_17281863 Show fit	1.83	ENST00000652132.1 ENST00000404085.7 ENST00000598347.2	ANKLE1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and LEM domain containing 1
chr1_+_37474572 Show fit	1.82	ENST00000373087.7	ZC3H12A Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 12A
chr1_-_206772484 Show fit	1.82	ENST00000423557.1	IL10 Ensembl NCBI GeneCards UniProt Show fit	interleukin 10
chr14_+_52314280 Show fit	1.77	ENST00000557436.1 ENST00000245457.6	PTGER2 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 2
chr16_+_1240698 Show fit	1.76	ENST00000561736.2 ENST00000338844.8 ENST00000461509.6	TPSAB1 Ensembl NCBI GeneCards UniProt Show fit	tryptase alpha/beta 1
chr19_+_7355589 Show fit	1.76	ENST00000671891.2	ARHGEF18 Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 18
chr11_+_1870150 Show fit	1.76	ENST00000429923.5 ENST00000418975.1 ENST00000406638.6	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte specific protein 1
chr16_+_29459913 Show fit	1.74	ENST00000360423.12	SULT1A4 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 4
chr16_-_74700786 Show fit	1.72	ENST00000306247.11 ENST00000575686.1	MLKL Ensembl NCBI GeneCards UniProt Show fit	mixed lineage kinase domain like pseudokinase
chr19_-_3606577 Show fit	1.72	ENST00000411851.3	TBXA2R Ensembl NCBI GeneCards UniProt Show fit	thromboxane A2 receptor
chr6_-_30687200 Show fit	1.71	ENST00000399199.7	PPP1R18 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 18
chr11_+_1870252 Show fit	1.69	ENST00000612798.4	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte specific protein 1
chr15_-_72783685 Show fit	1.69	ENST00000456471.3 ENST00000311669.12	ADPGK Ensembl NCBI GeneCards UniProt Show fit	ADP dependent glucokinase
chr14_-_91253925 Show fit	1.68	ENST00000531499.2	GPR68 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 68
chr21_-_44914271 Show fit	1.68	ENST00000522931.5	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr11_+_102317450 Show fit	1.67	ENST00000615299.4 ENST00000527309.2 ENST00000526421.6 ENST00000263464.9	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr6_-_73452124 Show fit	1.67	ENST00000680833.1	CGAS Ensembl NCBI GeneCards UniProt Show fit	cyclic GMP-AMP synthase
chr22_+_22899481 Show fit	1.66	ENST00000390322.2	IGLJ2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 2
chr19_-_7747559 Show fit	1.65	ENST00000394173.8	CD209 Ensembl NCBI GeneCards UniProt Show fit	CD209 molecule
chr6_-_41039202 Show fit	1.62	ENST00000244565.8	UNC5CL Ensembl NCBI GeneCards UniProt Show fit	unc-5 family C-terminal like
chr16_+_726936 Show fit	1.62	ENST00000549114.5 ENST00000341413.8 ENST00000562187.1 ENST00000564537.5 ENST00000389703.8	HAGHL Ensembl NCBI GeneCards UniProt Show fit	hydroxyacylglutathione hydrolase like
chr7_+_99374240 Show fit	1.61	ENST00000443222.6 ENST00000414376.5	ARPC1B Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 1B
chr7_+_45574358 Show fit	1.61	ENST00000297323.12	ADCY1 Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 1
chr3_-_46464868 Show fit	1.61	ENST00000417439.5 ENST00000231751.9 ENST00000431944.1	LTF Ensembl NCBI GeneCards UniProt Show fit	lactotransferrin
chr16_-_1230089 Show fit	1.59	ENST00000612142.1 ENST00000606293.5	TPSB2 Ensembl NCBI GeneCards UniProt Show fit	tryptase beta 2
chr11_+_47248924 Show fit	1.58	ENST00000481889.6 ENST00000436778.5 ENST00000531660.5 ENST00000407404.5	NR1H3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 3
chr6_-_149484965 Show fit	1.58	ENST00000409806.8	ZC3H12D Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 12D
chr16_+_30199255 Show fit	1.57	ENST00000338971.10	SULT1A3 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 3
chr9_-_121370275 Show fit	1.57	ENST00000538954.5	STOM Ensembl NCBI GeneCards UniProt Show fit	stomatin
chr11_+_65639860 Show fit	1.57	ENST00000527525.5	SIPA1 Ensembl NCBI GeneCards UniProt Show fit	signal-induced proliferation-associated 1
chr11_+_102317542 Show fit	1.56	ENST00000532808.5	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr11_+_36296281 Show fit	1.54	ENST00000530639.6	PRR5L Ensembl NCBI GeneCards UniProt Show fit	proline rich 5 like
chr8_-_21913661 Show fit	1.53	ENST00000518197.1	DOK2 Ensembl NCBI GeneCards UniProt Show fit	docking protein 2
chr8_-_69833338 Show fit	1.51	ENST00000524945.5	SLCO5A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 5A1
chr7_+_99374675 Show fit	1.51	ENST00000645391.1 ENST00000455009.6	ARPC1B Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 1B
chr1_+_32362537 Show fit	1.50	ENST00000373534.4	TSSK3 Ensembl NCBI GeneCards UniProt Show fit	testis specific serine kinase 3
chr9_+_133534807 Show fit	1.50	ENST00000393060.1	ADAMTSL2 Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 2
chr3_+_122055355 Show fit	1.49	ENST00000330540.7 ENST00000469710.5 ENST00000493101.5	CD86 Ensembl NCBI GeneCards UniProt Show fit	CD86 molecule
chr7_-_1940492 Show fit	1.47	ENST00000437877.1	MAD1L1 Ensembl NCBI GeneCards UniProt Show fit	mitotic arrest deficient 1 like 1
chr11_+_102317492 Show fit	1.47	ENST00000673846.1	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr6_-_90296824 Show fit	1.47	ENST00000257749.9	BACH2 Ensembl NCBI GeneCards UniProt Show fit	BTB domain and CNC homolog 2
chr7_+_2631978 Show fit	1.46	ENST00000258796.12	TTYH3 Ensembl NCBI GeneCards UniProt Show fit	tweety family member 3
chr2_-_207166818 Show fit	1.46	ENST00000423015.5	KLF7 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 7
chr22_+_22588155 Show fit	1.45	ENST00000390302.3	IGLV2-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-33 (non-functional)
chr9_+_133534697 Show fit	1.44	ENST00000651351.2	ADAMTSL2 Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 2
chr6_+_29827817 Show fit	1.43	ENST00000360323.11 ENST00000376818.7 ENST00000376815.3	HLA-G Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, G
chr9_-_35619542 Show fit	1.43	ENST00000396757.6	CD72 Ensembl NCBI GeneCards UniProt Show fit	CD72 molecule
chr16_+_30199860 Show fit	1.43	ENST00000395138.6	SULT1A3 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1A member 3
chr1_-_19980416 Show fit	1.41	ENST00000375111.7	PLA2G2A Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IIA
chr19_-_54313074 Show fit	1.40	ENST00000486742.2 ENST00000432233.8	LILRA5 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A5
chr22_-_50270353 Show fit	1.40	ENST00000330651.11	MAPK11 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 11
chr20_+_62656359 Show fit	1.39	ENST00000370507.5	SLCO4A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 4A1
chr8_+_141128581 Show fit	1.39	ENST00000519811.6	DENND3 Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 3
chr2_-_98731063 Show fit	1.37	ENST00000393487.6	MGAT4A Ensembl NCBI GeneCards UniProt Show fit	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr21_-_44928711 Show fit	1.37	ENST00000517563.5	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr20_+_38346474 Show fit	1.36	ENST00000217407.3	LBP Ensembl NCBI GeneCards UniProt Show fit	lipopolysaccharide binding protein
chr10_+_87659839 Show fit	1.36	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_-_156020789 Show fit	1.35	ENST00000531917.5 ENST00000480567.5 ENST00000526212.2 ENST00000529008.5 ENST00000496742.5 ENST00000295702.9	SSR2 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 2
chr7_-_150341615 Show fit	1.33	ENST00000223271.8 ENST00000466675.5 ENST00000482669.1 ENST00000467793.5	RARRES2 Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder 2
chr7_+_142492121 Show fit	1.32	ENST00000390374.3	TRBV7-6 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-6
chr19_+_45499610 Show fit	1.30	ENST00000396735.6	PPM1N Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr6_-_90296908 Show fit	1.30	ENST00000537989.5	BACH2 Ensembl NCBI GeneCards UniProt Show fit	BTB domain and CNC homolog 2
chr8_+_143558329 Show fit	1.30	ENST00000262580.9 ENST00000525721.1 ENST00000534018.5	GSDMD Ensembl NCBI GeneCards UniProt Show fit	gasdermin D
chr5_+_111224374 Show fit	1.28	ENST00000282356.9	CAMK4 Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase IV
chr8_+_141128612 Show fit	1.27	ENST00000518347.5 ENST00000262585.6 ENST00000520986.5 ENST00000523058.5 ENST00000518668.5	DENND3 Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 3
chr11_+_62419025 Show fit	1.26	ENST00000278282.3	SCGB1A1 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 1A member 1
chr11_+_8683201 Show fit	1.24	ENST00000526562.5 ENST00000525981.1	RPL27A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L27a
chr6_-_53348902 Show fit	1.24	ENST00000370913.5 ENST00000304434.11	ELOVL5 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 5
chr13_-_46390042 Show fit	1.23	ENST00000389908.7	RUBCNL Ensembl NCBI GeneCards UniProt Show fit	rubicon like autophagy enhancer
chr19_-_13102848 Show fit	1.23	ENST00000264824.5	LYL1 Ensembl NCBI GeneCards UniProt Show fit	LYL1 basic helix-loop-helix family member
chr4_+_2798564 Show fit	1.23	ENST00000504294.5	SH3BP2 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding protein 2
chr22_+_37639660 Show fit	1.22	ENST00000649765.2 ENST00000451997.6	SH3BP1 Ensembl NCBI GeneCards UniProt Show fit ENSG00000285304.1 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding protein 1 novel protein
chr19_+_17281645 Show fit	1.22	ENST00000394458.7 ENST00000594072.6	ANKLE1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and LEM domain containing 1
chr11_+_8682782 Show fit	1.21	ENST00000531978.5 ENST00000524496.5 ENST00000532359.5 ENST00000314138.11 ENST00000530022.5	RPL27A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L27a
chr20_+_33993932 Show fit	1.21	ENST00000333552.9	RALY Ensembl NCBI GeneCards UniProt Show fit	RALY heterogeneous nuclear ribonucleoprotein
chr7_-_100573865 Show fit	1.20	ENST00000622764.3	SAP25 Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 25
chr9_+_127716073 Show fit	1.20	ENST00000373289.4	TTC16 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 16
chr1_+_12166978 Show fit	1.19	ENST00000376259.7 ENST00000536782.2	TNFRSF1B Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1B
chr19_-_14475307 Show fit	1.19	ENST00000292513.4	PTGER1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 1
chr22_+_49918733 Show fit	1.18	ENST00000407217.7 ENST00000403427.3	CRELD2 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich with EGF like domains 2
chr17_-_75405486 Show fit	1.18	ENST00000392562.5	GRB2 Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor bound protein 2
chr5_+_111223905 Show fit	1.18	ENST00000512453.5	CAMK4 Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase IV
chr6_+_32154131 Show fit	1.18	ENST00000375143.6 ENST00000324816.11 ENST00000424499.1	PPT2 Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr19_+_47332167 Show fit	1.17	ENST00000595464.3	C5AR2 Ensembl NCBI GeneCards UniProt Show fit	complement component 5a receptor 2
chr14_+_21768482 Show fit	1.17	ENST00000390428.3	TRAV6 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 6
chr5_-_132011580 Show fit	1.17	ENST00000651250.1 ENST00000434099.6 ENST00000296869.9 ENST00000651356.1 ENST00000651883.2	ACSL6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 6
chr3_+_186931344 Show fit	1.17	ENST00000417392.5	ST6GAL1 Ensembl NCBI GeneCards UniProt Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr15_+_69452811 Show fit	1.17	ENST00000357790.5 ENST00000260379.11 ENST00000560274.1	RPLP1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein lateral stalk subunit P1
chr5_-_132011811 Show fit	1.16	ENST00000379255.5 ENST00000430403.5 ENST00000357096.5	ACSL6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	5.9	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
1.6	4.9	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
1.6	17.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
1.2	208.7	GO:0006958	complement activation, classical pathway(GO:0006958)
1.2	4.8	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.2	4.8	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.0	3.1	GO:0002372	myeloid dendritic cell cytokine production(GO:0002372)
1.0	3.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.0	4.1	GO:0046968	peptide antigen transport(GO:0046968)
0.8	2.4	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.7	3.5	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.7	2.1	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
0.6	1.8	GO:2000627	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.6	1.8	GO:0060302	negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.6	1.8	GO:0038178	complement component C5a signaling pathway(GO:0038178)
0.6	3.0	GO:0032796	uropod organization(GO:0032796)
0.6	2.3	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.5	5.9	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5	2.1	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5	0.5	GO:0002458	peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465)
0.5	1.5	GO:0043017	negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.5	1.4	GO:0000103	sulfate assimilation(GO:0000103)
0.4	2.6	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.4	1.3	GO:0035915	pore formation in membrane of other organism(GO:0035915)
0.4	3.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4	2.9	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.4	1.6	GO:0044010	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.4	2.4	GO:0015722	canalicular bile acid transport(GO:0015722)
0.4	2.8	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
0.4	1.6	GO:0042631	cellular response to water deprivation(GO:0042631)
0.4	3.0	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.4	1.1	GO:0021793	chemorepulsion of branchiomotor axon(GO:0021793)
0.3	1.0	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.3	1.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	2.6	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.3	1.0	GO:0071449	cellular response to lipid hydroperoxide(GO:0071449)
0.3	70.9	GO:0002377	immunoglobulin production(GO:0002377)
0.3	2.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.3	1.9	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3	0.9	GO:0006212	uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.3	1.7	GO:1902283	negative regulation of primary amine oxidase activity(GO:1902283)
0.3	1.4	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.3	0.8	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.3	7.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.3	0.8	GO:0030974	thiamine pyrophosphate transport(GO:0030974)
0.3	2.4	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.3	1.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.3	0.8	GO:0031204	posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3	2.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.3	1.3	GO:0001575	globoside metabolic process(GO:0001575)
0.3	1.3	GO:0010193	response to ozone(GO:0010193)
0.2	0.7	GO:1903450	regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.2	1.0	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.2	4.7	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2	1.1	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2	0.7	GO:1904863	regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.2	2.9	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	1.3	GO:0019732	antifungal humoral response(GO:0019732) antifungal innate immune response(GO:0061760)
0.2	0.9	GO:0051801	cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.2	4.8	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.2	2.2	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2	1.0	GO:0038156	interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.2	0.6	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.2	1.0	GO:0071603	retinal blood vessel morphogenesis(GO:0061304) endothelial cell-cell adhesion(GO:0071603)
0.2	2.9	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.2	0.6	GO:1904887	regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.2	2.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.6	GO:0060003	regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) copper ion export(GO:0060003)
0.2	0.5	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2	0.5	GO:0016267	O-glycan processing, core 1(GO:0016267)
0.2	0.7	GO:0033590	acetaldehyde metabolic process(GO:0006117) response to cobalamin(GO:0033590)
0.2	0.7	GO:0014028	notochord formation(GO:0014028)
0.2	0.7	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2	1.7	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.2	1.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.2	1.4	GO:0000012	single strand break repair(GO:0000012)
0.2	1.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	0.6	GO:0060734	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2	0.5	GO:0080120	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2	0.9	GO:0001757	somite specification(GO:0001757)
0.1	0.6	GO:0033037	polysaccharide localization(GO:0033037)
0.1	11.5	GO:0006953	acute-phase response(GO:0006953)
0.1	1.3	GO:0071673	positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.1	0.9	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	5.2	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	3.2	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	3.9	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.1	0.7	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	1.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.4	GO:0097212	cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.1	0.2	GO:0019046	release from viral latency(GO:0019046)
0.1	0.7	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	4.9	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	1.5	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	5.3	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.5	GO:0042361	menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1	0.8	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.8	GO:0070383	DNA cytosine deamination(GO:0070383)
0.1	0.2	GO:0051885	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of anagen(GO:0051885)
0.1	0.5	GO:0035854	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1	0.4	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	0.9	GO:0072343	pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1	0.5	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	1.5	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.1	1.3	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.1	0.3	GO:1903988	spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1	2.1	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.7	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	1.4	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	4.9	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	2.3	GO:0002467	germinal center formation(GO:0002467)
0.1	1.1	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1	0.6	GO:0072144	glomerular mesangial cell development(GO:0072144)
0.1	0.6	GO:0021633	optic nerve structural organization(GO:0021633)
0.1	0.7	GO:0023035	CD40 signaling pathway(GO:0023035)
0.1	1.8	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.1	0.6	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.1	0.5	GO:0006788	heme oxidation(GO:0006788)
0.1	2.4	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	1.9	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.1	0.7	GO:0051414	response to cortisol(GO:0051414)
0.1	0.4	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.1	4.0	GO:0070207	protein homotrimerization(GO:0070207)
0.1	0.4	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1	4.8	GO:0043277	apoptotic cell clearance(GO:0043277)
0.1	1.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	1.5	GO:0038203	TORC2 signaling(GO:0038203)
0.1	2.4	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	2.7	GO:0036344	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1	0.5	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.4	GO:0000050	urea cycle(GO:0000050)
0.1	2.8	GO:0019835	cytolysis(GO:0019835)
0.1	0.3	GO:0070895	transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1	0.3	GO:0042427	serotonin biosynthetic process(GO:0042427)
0.1	0.4	GO:1900220	negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.6	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	1.7	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1	1.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.1	1.6	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	3.0	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.1	0.4	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0048561	establishment of organ orientation(GO:0048561)
0.1	1.5	GO:0015816	glycine transport(GO:0015816)
0.1	0.7	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.1	0.6	GO:0070995	NADPH oxidation(GO:0070995)
0.1	1.6	GO:0010226	response to lithium ion(GO:0010226)
0.1	0.4	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1	1.0	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	2.3	GO:0006525	arginine metabolic process(GO:0006525)
0.1	0.4	GO:1903232	melanosome assembly(GO:1903232)
0.1	21.8	GO:0002250	adaptive immune response(GO:0002250)
0.1	0.8	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.1	1.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.8	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	0.4	GO:0003363	lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1	0.5	GO:0061430	bone trabecula morphogenesis(GO:0061430)
0.1	0.5	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.4	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.6	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	2.3	GO:0050779	RNA destabilization(GO:0050779)
0.1	0.8	GO:0060033	anatomical structure regression(GO:0060033)
0.1	0.6	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.1	0.7	GO:0001887	selenium compound metabolic process(GO:0001887)
0.1	0.2	GO:0021539	subthalamus development(GO:0021539)
0.1	0.3	GO:0098838	reduced folate transmembrane transport(GO:0098838)
0.1	0.7	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	2.1	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1	0.7	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.6	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.8	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.3	GO:0015853	adenine transport(GO:0015853)
0.0	1.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.3	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.5	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.6	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	3.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.8	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.0	0.4	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.0	0.7	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.3	GO:0019236	response to pheromone(GO:0019236)
0.0	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	2.0	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.2	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	1.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	0.2	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0	0.4	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.6	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	4.0	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.0	0.3	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.4	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.0	0.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	4.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.2	GO:0045204	MAPK export from nucleus(GO:0045204)
0.0	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.5	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.9	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.0	0.6	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.2	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.6	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.2	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	1.4	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	0.5	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	1.0	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.5	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	2.5	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	0.3	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.9	GO:0009395	phospholipid catabolic process(GO:0009395)
0.0	0.4	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	2.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.5	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	2.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.5	GO:0001659	temperature homeostasis(GO:0001659)
0.0	0.4	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.5	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0000066	mitochondrial ornithine transport(GO:0000066)
0.0	0.1	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.2	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.0	0.0	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.0	0.8	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.2	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	1.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.5	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.3	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.9	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.0	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.9	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0	1.1	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	0.4	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.2	GO:0051601	exocyst localization(GO:0051601)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.3	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.2	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.2	GO:1990118	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.5	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.2	GO:0006882	cellular zinc ion homeostasis(GO:0006882)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	15.9	GO:0071752	dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
1.0	3.1	GO:0036284	tubulobulbar complex(GO:0036284)
0.7	2.1	GO:0030312	external encapsulating structure(GO:0030312)
0.7	35.8	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.6	1.9	GO:0036117	hyaluranon cable(GO:0036117)
0.4	1.9	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4	3.0	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.4	1.5	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3	73.5	GO:0072562	blood microparticle(GO:0072562)
0.3	1.0	GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.3	1.6	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2	7.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2	2.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	1.0	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2	1.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.6	GO:0099400	cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.2	1.8	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2	0.7	GO:0035525	NF-kappaB p50/p65 complex(GO:0035525)
0.1	1.2	GO:0043196	varicosity(GO:0043196)
0.1	1.2	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.8	GO:0002079	inner acrosomal membrane(GO:0002079)
0.1	1.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.1	0.8	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	1.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.8	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.4	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	12.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	6.1	GO:0031527	filopodium membrane(GO:0031527)
0.1	1.3	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	2.1	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	0.6	GO:1990031	pinceau fiber(GO:1990031)
0.1	7.4	GO:0001772	immunological synapse(GO:0001772)
0.1	0.9	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.3	GO:0098855	HCN channel complex(GO:0098855)
0.1	1.3	GO:0005605	basal lamina(GO:0005605)
0.1	0.7	GO:0098536	deuterosome(GO:0098536)
0.1	1.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.3	GO:0071817	MMXD complex(GO:0071817)
0.1	0.3	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.1	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.4	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	1.0	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	5.2	GO:0015030	Cajal body(GO:0015030)
0.1	1.5	GO:0031932	TORC2 complex(GO:0031932)
0.1	6.2	GO:0043202	lysosomal lumen(GO:0043202)
0.1	2.0	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.2	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.2	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	5.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.6	GO:0000322	storage vacuole(GO:0000322)
0.0	0.4	GO:0070449	elongin complex(GO:0070449)
0.0	84.1	GO:0005615	extracellular space(GO:0005615)
0.0	2.9	GO:0005581	collagen trimer(GO:0005581)
0.0	8.3	GO:0001650	fibrillar center(GO:0001650)
0.0	4.1	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.4	GO:0044327	dendritic spine head(GO:0044327)
0.0	1.0	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	1.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	5.6	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	2.4	GO:0030175	filopodium(GO:0030175)
0.0	0.6	GO:0033010	paranodal junction(GO:0033010)
0.0	3.1	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	1.5	GO:0005643	nuclear pore(GO:0005643)
0.0	2.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	3.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.6	GO:0005902	microvillus(GO:0005902)
0.0	1.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.7	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	2.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.4	GO:0030897	HOPS complex(GO:0030897)
0.0	0.8	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.7	GO:0005811	lipid particle(GO:0005811)
0.0	0.8	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	1.8	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.5	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	1.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	2.1	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	95.1	GO:0005576	extracellular region(GO:0005576)
0.0	4.4	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0070461	SAGA-type complex(GO:0070461)
0.0	0.5	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.6	GO:0016592	mediator complex(GO:0016592)
0.0	0.8	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.8	GO:0030666	endocytic vesicle membrane(GO:0030666)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.9	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.6	4.8	GO:0008859	exoribonuclease II activity(GO:0008859)
1.1	303.7	GO:0003823	antigen binding(GO:0003823)
1.0	4.8	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.8	2.4	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.8	2.4	GO:0015432	bile acid-exporting ATPase activity(GO:0015432)
0.8	2.3	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.7	3.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.7	6.6	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6	1.8	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.5	3.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.5	2.9	GO:0050436	microfibril binding(GO:0050436)
0.5	6.3	GO:0016015	morphogen activity(GO:0016015)
0.5	1.9	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.4	3.5	GO:0032810	sterol response element binding(GO:0032810)
0.4	4.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	1.9	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.4	3.3	GO:0071723	lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.4	4.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4	1.4	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3	1.7	GO:0052596	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3	3.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.3	2.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.3	0.8	GO:0090422	thiamine pyrophosphate transporter activity(GO:0090422)
0.3	1.1	GO:0005011	macrophage colony-stimulating factor receptor activity(GO:0005011)
0.2	0.7	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2	2.9	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	2.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	0.9	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.2	1.0	GO:0004914	interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2	1.7	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2	1.1	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.2	0.6	GO:0036479	GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.2	0.6	GO:0004008	copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.2	0.9	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.2	0.5	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2	1.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	2.2	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.2	0.7	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2	0.7	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.2	1.0	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
0.2	0.6	GO:0001855	complement component C4b binding(GO:0001855)
0.2	3.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2	3.1	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2	1.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1	0.6	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1	2.8	GO:0031996	thioesterase binding(GO:0031996)
0.1	3.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	4.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	1.7	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	2.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	1.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	1.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	3.9	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.7	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	1.0	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.1	7.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	3.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.6	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1	1.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	2.1	GO:0004568	chitinase activity(GO:0004568)
0.1	3.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.7	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	3.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	4.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.3	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.3	GO:0097689	iron channel activity(GO:0097689)
0.1	2.3	GO:0005522	profilin binding(GO:0005522)
0.1	0.5	GO:0004905	type I interferon receptor activity(GO:0004905)
0.1	3.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.8	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.1	0.4	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.1	0.5	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	0.5	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	0.5	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	1.2	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	1.0	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.3	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.1	0.4	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1	0.6	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1	0.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.8	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	1.5	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	12.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.6	GO:0004046	aminoacylase activity(GO:0004046)
0.1	1.6	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	0.9	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.3	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.8	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.8	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.5	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	1.0	GO:1901612	cardiolipin binding(GO:1901612)
0.1	0.4	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	1.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.5	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.8	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.5	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	1.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	5.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.7	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.9	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.5	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	1.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	1.0	GO:0043295	glutathione binding(GO:0043295)
0.0	0.6	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	1.3	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0030290	sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0	0.7	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	1.1	GO:0008527	taste receptor activity(GO:0008527)
0.0	1.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.5	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	2.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.0	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	1.0	GO:0070330	aromatase activity(GO:0070330)
0.0	0.7	GO:0008430	selenium binding(GO:0008430)
0.0	0.3	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.8	GO:0001848	complement binding(GO:0001848)
0.0	0.6	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.5	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.7	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.5	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.6	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	7.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.4	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.6	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	5.5	GO:0005125	cytokine activity(GO:0005125)
0.0	1.6	GO:0050699	WW domain binding(GO:0050699)
0.0	1.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.6	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.5	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	5.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.9	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	2.0	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0	0.1	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.1	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0	1.1	GO:0071837	HMG box domain binding(GO:0071837)
0.0	4.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.6	GO:0043495	protein anchor(GO:0043495)
0.0	4.3	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.3	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	1.6	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.2	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.5	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.5	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.0	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.0	0.6	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.6	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.1	GO:0050254	rhodopsin kinase activity(GO:0050254)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.3	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.3	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	1.3	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	3.7	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	1.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.4	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.8	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	3.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.0	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	2.6	GO:0003735	structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	10.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	9.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	12.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	6.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	2.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	2.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	4.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	4.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	3.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	4.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	5.7	PID BMP PATHWAY	BMP receptor signaling
0.1	3.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	0.8	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	4.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	9.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	1.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	3.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	5.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	3.0	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	6.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	6.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	9.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	9.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	9.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.3	2.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2	3.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	3.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	10.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	3.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	3.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	4.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	2.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	6.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	2.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	9.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	4.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	10.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	3.6	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	2.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	4.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	1.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	1.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	5.1	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	3.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	5.5	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	2.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.6	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	2.5	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	2.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Results for ESR1

Z-value: 3.47

Motif logo

Transcription factors associated with ESR1

Activity-expression correlation:

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: