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avrg: Illumina Body Map 2 (GSE30611)
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Results for ETS1
Z-value: 3.52
Motif logo
Transcription factors associated with ETS1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ETS1
|
ENSG00000134954.14 | ETS1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETS1 | hg38_v1_chr11_-_128587551_128587566 | 0.81 | 2.1e-08 | Click! |
Activity profile of ETS1 motif
Sorted Z-values of ETS1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ETS1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 11.5 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 3.5 | 17.4 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 3.3 | 16.7 | GO:2000473 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
| 3.3 | 10.0 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 3.1 | 9.2 | GO:1902227 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) |
| 2.9 | 8.6 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 2.5 | 12.7 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 2.4 | 7.2 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 2.3 | 7.0 | GO:0019085 | early viral transcription(GO:0019085) |
| 2.2 | 13.0 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 2.2 | 8.6 | GO:0045401 | positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) |
| 2.0 | 16.3 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 1.9 | 13.3 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 1.9 | 18.6 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 1.8 | 9.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 1.8 | 5.4 | GO:0061485 | memory T cell proliferation(GO:0061485) |
| 1.8 | 7.2 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.8 | 30.1 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 1.8 | 7.0 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 1.7 | 18.5 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 1.6 | 6.5 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 1.6 | 8.1 | GO:0039513 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 1.5 | 5.8 | GO:0002625 | regulation of T cell antigen processing and presentation(GO:0002625) |
| 1.4 | 9.9 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 1.4 | 1.4 | GO:1902214 | regulation of interleukin-4-mediated signaling pathway(GO:1902214) |
| 1.4 | 4.1 | GO:1904845 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 1.4 | 8.1 | GO:0009051 | NADPH regeneration(GO:0006740) pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 1.3 | 24.8 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 1.2 | 3.7 | GO:0032701 | negative regulation of interleukin-18 production(GO:0032701) |
| 1.2 | 6.1 | GO:0019086 | late viral transcription(GO:0019086) |
| 1.2 | 6.1 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 1.2 | 3.6 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 1.2 | 2.4 | GO:2000562 | negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) |
| 1.2 | 9.5 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 1.2 | 3.5 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 1.2 | 8.2 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 1.2 | 4.6 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 1.1 | 22.5 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 1.1 | 4.4 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 1.1 | 10.0 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 1.1 | 5.5 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 1.1 | 4.4 | GO:2000754 | regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755) |
| 1.0 | 8.4 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 1.0 | 1.0 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 1.0 | 3.1 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 1.0 | 3.1 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 1.0 | 4.0 | GO:0071348 | cellular response to interleukin-11(GO:0071348) |
| 1.0 | 2.0 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
| 1.0 | 23.3 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.9 | 5.7 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.9 | 2.8 | GO:1903006 | regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 0.9 | 2.7 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.9 | 2.6 | GO:0002339 | B cell selection(GO:0002339) |
| 0.9 | 0.9 | GO:0060876 | semicircular canal formation(GO:0060876) |
| 0.8 | 3.3 | GO:0036229 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 0.8 | 4.2 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.8 | 3.3 | GO:0035261 | external genitalia morphogenesis(GO:0035261) |
| 0.8 | 5.8 | GO:0098758 | response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) |
| 0.8 | 2.5 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.8 | 0.8 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.8 | 19.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.8 | 2.4 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 0.8 | 3.9 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.8 | 33.1 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.8 | 5.5 | GO:2000330 | positive regulation of T-helper 17 cell lineage commitment(GO:2000330) |
| 0.8 | 3.1 | GO:0046730 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 0.8 | 2.3 | GO:0044725 | chromatin reprogramming in the zygote(GO:0044725) |
| 0.8 | 6.1 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.8 | 1.5 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.7 | 2.2 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.7 | 2.2 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 0.7 | 2.9 | GO:0090135 | actin filament branching(GO:0090135) |
| 0.7 | 4.4 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.7 | 2.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.7 | 2.9 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.7 | 2.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.7 | 5.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.7 | 2.1 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.7 | 3.4 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.7 | 2.6 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.7 | 4.6 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 0.7 | 2.0 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.6 | 5.2 | GO:0035696 | monocyte extravasation(GO:0035696) |
| 0.6 | 1.9 | GO:0006407 | rRNA export from nucleus(GO:0006407) |
| 0.6 | 6.3 | GO:0070970 | interleukin-2 secretion(GO:0070970) |
| 0.6 | 17.6 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.6 | 3.1 | GO:1903626 | positive regulation of DNA catabolic process(GO:1903626) |
| 0.6 | 17.2 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.6 | 4.8 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.6 | 4.1 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.6 | 8.0 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 0.6 | 1.7 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.6 | 1.1 | GO:0034756 | regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) |
| 0.6 | 4.5 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.6 | 1.7 | GO:0043311 | regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568) |
| 0.6 | 2.8 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.6 | 4.4 | GO:0048302 | regulation of isotype switching to IgG isotypes(GO:0048302) |
| 0.5 | 1.6 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.5 | 2.2 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.5 | 19.6 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.5 | 7.0 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.5 | 1.6 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.5 | 4.8 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.5 | 1.6 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 0.5 | 2.1 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.5 | 2.1 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.5 | 1.5 | GO:0045553 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 0.5 | 6.5 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
| 0.5 | 3.0 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.5 | 2.5 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.5 | 0.5 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.5 | 4.4 | GO:0046070 | dGTP metabolic process(GO:0046070) |
| 0.5 | 3.4 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.5 | 4.3 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.5 | 0.9 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.5 | 30.6 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.5 | 6.1 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.5 | 1.9 | GO:0042247 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 0.5 | 4.2 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.5 | 1.4 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.5 | 11.6 | GO:0002717 | positive regulation of natural killer cell mediated immunity(GO:0002717) |
| 0.5 | 43.7 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.5 | 1.8 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 0.4 | 3.1 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.4 | 1.3 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 0.4 | 2.6 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.4 | 2.6 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.4 | 4.3 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.4 | 1.3 | GO:1904528 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528) |
| 0.4 | 2.1 | GO:0042779 | tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) |
| 0.4 | 1.7 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.4 | 3.3 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.4 | 3.2 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) |
| 0.4 | 4.4 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.4 | 3.2 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 0.4 | 5.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.4 | 2.3 | GO:0051563 | smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) |
| 0.4 | 1.6 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.4 | 2.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.4 | 0.8 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.4 | 15.0 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.4 | 2.7 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.4 | 9.9 | GO:0071380 | cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.4 | 1.1 | GO:0071962 | mitotic sister chromatid cohesion, centromeric(GO:0071962) |
| 0.4 | 1.1 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.4 | 3.3 | GO:0042269 | regulation of natural killer cell mediated cytotoxicity(GO:0042269) |
| 0.4 | 14.8 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.4 | 2.9 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.4 | 2.1 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.4 | 2.9 | GO:1903223 | positive regulation of oxidative stress-induced neuron death(GO:1903223) |
| 0.4 | 1.1 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 0.4 | 3.5 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.4 | 1.8 | GO:0072011 | glomerular endothelium development(GO:0072011) |
| 0.3 | 6.6 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.3 | 1.0 | GO:0001928 | regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178) |
| 0.3 | 1.0 | GO:1903259 | exon-exon junction complex disassembly(GO:1903259) |
| 0.3 | 0.3 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 0.3 | 1.0 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.3 | 3.1 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.3 | 12.5 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.3 | 1.0 | GO:0090108 | positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340) |
| 0.3 | 3.4 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.3 | 6.3 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.3 | 22.4 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.3 | 3.0 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 0.3 | 51.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.3 | 1.3 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.3 | 5.5 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.3 | 4.8 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.3 | 2.9 | GO:2001171 | positive regulation of ATP biosynthetic process(GO:2001171) |
| 0.3 | 1.9 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 4.7 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.3 | 7.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.3 | 1.2 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 0.3 | 1.8 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 0.3 | 0.6 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.3 | 3.3 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 0.3 | 0.9 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.3 | 1.8 | GO:1903251 | multi-ciliated epithelial cell differentiation(GO:1903251) |
| 0.3 | 3.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.3 | 5.0 | GO:0098969 | neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 0.3 | 1.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.3 | 0.5 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.3 | 3.0 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.3 | 4.6 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.3 | 5.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.3 | 2.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.3 | 2.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.3 | 3.2 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 5.3 | GO:0072678 | T cell migration(GO:0072678) |
| 0.3 | 5.0 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) |
| 0.3 | 3.9 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.3 | 5.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.3 | 6.7 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.3 | 2.6 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.3 | 8.2 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.3 | 0.5 | GO:1903236 | regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.3 | 3.5 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.2 | 2.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.2 | 0.7 | GO:0075713 | establishment of integrated proviral latency(GO:0075713) |
| 0.2 | 2.0 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.2 | 5.8 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.2 | 3.6 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 0.2 | 2.4 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.2 | 1.0 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.2 | 1.7 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.2 | 0.9 | GO:2000843 | testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 0.2 | 9.9 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.2 | 1.6 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.2 | 0.9 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.2 | 2.3 | GO:0009826 | unidimensional cell growth(GO:0009826) |
| 0.2 | 1.4 | GO:0090230 | regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234) |
| 0.2 | 2.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.2 | 3.4 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.2 | 3.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 14.9 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.2 | 16.4 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.2 | 1.3 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.2 | 7.1 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.2 | 2.0 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.2 | 0.4 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.2 | 1.3 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.2 | 0.9 | GO:1904980 | positive regulation of endosome organization(GO:1904980) |
| 0.2 | 0.9 | GO:0034552 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 0.2 | 1.9 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.2 | 1.5 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.2 | 2.3 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.2 | 0.6 | GO:0100057 | regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828) |
| 0.2 | 11.3 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.2 | 4.4 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.2 | 1.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.2 | 1.0 | GO:1902659 | hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.2 | 1.8 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 2.0 | GO:0071421 | manganese ion transmembrane transport(GO:0071421) |
| 0.2 | 1.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 4.9 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.2 | 0.2 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.2 | 3.0 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.2 | 1.2 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.2 | 1.2 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.2 | 3.3 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 1.0 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.2 | 2.3 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.2 | 0.8 | GO:1903423 | positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423) |
| 0.2 | 1.9 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.2 | 2.9 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.2 | 1.3 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.2 | 1.1 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.2 | 0.2 | GO:0046619 | optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619) |
| 0.2 | 0.9 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.2 | 2.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.2 | 1.5 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.2 | 7.6 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.2 | 0.5 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.2 | 6.4 | GO:0055069 | zinc ion homeostasis(GO:0055069) |
| 0.2 | 0.7 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.2 | 4.2 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.2 | 4.5 | GO:0050798 | activated T cell proliferation(GO:0050798) |
| 0.2 | 1.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 1.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.2 | 0.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.2 | 1.7 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 0.1 | 7.6 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 4.6 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.1 | 12.8 | GO:0007077 | mitotic nuclear envelope disassembly(GO:0007077) |
| 0.1 | 0.7 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 3.5 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 1.6 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 1.2 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 2.2 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.1 | 1.2 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.1 | 4.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.1 | 1.7 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 2.7 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 2.6 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.1 | 4.9 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) |
| 0.1 | 0.6 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.1 | 0.4 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.1 | 10.3 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.1 | 2.4 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.1 | 0.1 | GO:2000152 | regulation of ubiquitin-specific protease activity(GO:2000152) |
| 0.1 | 1.8 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 1.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 0.5 | GO:0040034 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) |
| 0.1 | 2.4 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.5 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 5.1 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.1 | 2.4 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 0.6 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.1 | 0.8 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 2.0 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.1 | 0.2 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
| 0.1 | 5.4 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.1 | 1.5 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.1 | 1.5 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.1 | 5.5 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 5.6 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 1.3 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 5.7 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
| 0.1 | 4.8 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 2.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.1 | 1.3 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.1 | 1.3 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.1 | 0.8 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.1 | 3.2 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 1.4 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 0.9 | GO:0043301 | negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) |
| 0.1 | 3.3 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.1 | 1.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 3.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.1 | 2.0 | GO:0039532 | negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) |
| 0.1 | 0.5 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.1 | 2.2 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.1 | 0.3 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.1 | 2.4 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 1.1 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 2.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.4 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 0.1 | 0.5 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
| 0.1 | 0.3 | GO:0061146 | mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) |
| 0.1 | 2.1 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.1 | 2.7 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.1 | 1.1 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.1 | 2.0 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 1.5 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.1 | 2.8 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 5.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 0.3 | GO:0035048 | splicing factor protein import into nucleus(GO:0035048) |
| 0.1 | 69.4 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.1 | 1.1 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.1 | 1.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 1.4 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.5 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.1 | 1.0 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 0.5 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 2.1 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.1 | 0.5 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.1 | 1.1 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.1 | 5.4 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.1 | 2.8 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 1.5 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 1.5 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 3.1 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.1 | 0.6 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.1 | 1.9 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.1 | 0.6 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.3 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 3.3 | GO:1900077 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.1 | 1.0 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 0.6 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.1 | 0.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 11.3 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) |
| 0.1 | 1.6 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.4 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.1 | 0.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 6.8 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.1 | 0.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 0.4 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.1 | 2.1 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.1 | 0.2 | GO:2000010 | positive regulation of protein localization to cell surface(GO:2000010) |
| 0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 0.3 | GO:0052150 | suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) negative regulation by symbiont of host programmed cell death(GO:0052041) modulation by symbiont of host apoptotic process(GO:0052150) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) |
| 0.1 | 0.4 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.1 | 0.3 | GO:0072560 | type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.1 | 2.0 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 0.9 | GO:0044821 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 0.4 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 1.0 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 0.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 2.1 | GO:0001696 | gastric acid secretion(GO:0001696) |
| 0.1 | 0.5 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 2.0 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.1 | 2.0 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.1 | 0.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.1 | 0.5 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.1 | 0.2 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.1 | 0.7 | GO:0015866 | ADP transport(GO:0015866) |
| 0.1 | 0.3 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.5 | GO:0090241 | negative regulation of histone H4 acetylation(GO:0090241) |
| 0.1 | 0.8 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.1 | 0.7 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 0.4 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.1 | 2.7 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 2.2 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.1 | 1.0 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
| 0.1 | 3.3 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.1 | 0.9 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.1 | 1.7 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.1 | 1.7 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.1 | 0.9 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.1 | 5.4 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.1 | 0.7 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.1 | 0.1 | GO:0071922 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 0.0 | 0.8 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.1 | GO:0032258 | CVT pathway(GO:0032258) |
| 0.0 | 1.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 1.1 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.0 | 0.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 1.0 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 0.5 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.4 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.0 | 4.1 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 2.0 | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) |
| 0.0 | 2.0 | GO:0038034 | signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192) |
| 0.0 | 0.7 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.3 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.0 | 0.3 | GO:0045713 | low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) |
| 0.0 | 0.2 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.0 | 0.2 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
| 0.0 | 0.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.0 | 3.3 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 1.2 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.0 | 0.3 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 0.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 4.2 | GO:0042633 | molting cycle(GO:0042303) hair cycle(GO:0042633) |
| 0.0 | 1.7 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.3 | GO:0016081 | synaptic vesicle docking(GO:0016081) endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.0 | 0.4 | GO:0006983 | ER overload response(GO:0006983) |
| 0.0 | 1.3 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 39.2 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.0 | 0.1 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.0 | 0.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.7 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 1.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.1 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.0 | 0.9 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.0 | 0.1 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.0 | 2.1 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 0.0 | 1.6 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.0 | 0.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 0.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.0 | 1.0 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 0.5 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.0 | 1.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.5 | GO:0060039 | pericardium development(GO:0060039) |
| 0.0 | 0.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.0 | 3.6 | GO:0006909 | phagocytosis(GO:0006909) |
| 0.0 | 0.1 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.0 | 0.6 | GO:0042304 | regulation of fatty acid biosynthetic process(GO:0042304) |
| 0.0 | 0.3 | GO:2000505 | regulation of energy homeostasis(GO:2000505) |
| 0.0 | 0.2 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 1.8 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.3 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.1 | GO:0033319 | UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320) |
| 0.0 | 0.9 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.6 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 0.1 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.0 | 0.6 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.3 | GO:0043928 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.3 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 0.5 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.1 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 3.3 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.5 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) |
| 0.0 | 0.1 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.7 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.1 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.0 | 0.3 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 0.2 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 1.3 | GO:0006413 | translational initiation(GO:0006413) |
| 0.0 | 0.2 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.0 | 1.2 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.4 | GO:0009251 | glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.0 | 0.2 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.1 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.0 | 0.1 | GO:0006235 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.0 | 1.1 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.6 | GO:0007091 | metaphase/anaphase transition of mitotic cell cycle(GO:0007091) |
| 0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.4 | GO:0050919 | negative chemotaxis(GO:0050919) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 44.9 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 3.2 | 13.0 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 3.1 | 15.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 2.5 | 12.7 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 2.3 | 25.3 | GO:0032010 | phagolysosome(GO:0032010) |
| 2.2 | 26.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 1.9 | 17.4 | GO:0044194 | cytolytic granule(GO:0044194) |
| 1.4 | 30.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 1.2 | 9.5 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 1.1 | 4.5 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 1.1 | 3.3 | GO:0032116 | SMC loading complex(GO:0032116) |
| 1.0 | 3.0 | GO:0042022 | interleukin-12 receptor complex(GO:0042022) |
| 0.9 | 4.6 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.9 | 5.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.8 | 6.7 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.8 | 34.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.8 | 19.8 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.8 | 4.7 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.8 | 30.0 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.8 | 14.8 | GO:0032059 | bleb(GO:0032059) |
| 0.8 | 4.6 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.7 | 4.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.6 | 5.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.6 | 11.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.6 | 6.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.6 | 1.7 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.6 | 2.3 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.6 | 1.7 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.5 | 32.1 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.5 | 1.6 | GO:0016590 | ACF complex(GO:0016590) |
| 0.5 | 1.5 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.5 | 6.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.5 | 3.5 | GO:1990031 | pinceau fiber(GO:1990031) |
| 0.5 | 6.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.5 | 2.4 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.5 | 15.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.5 | 1.4 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.5 | 4.7 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.5 | 1.4 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.4 | 1.3 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 0.4 | 2.1 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.4 | 2.1 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.4 | 12.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.4 | 6.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.4 | 2.8 | GO:0089701 | U2AF(GO:0089701) |
| 0.4 | 5.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.4 | 2.8 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.4 | 2.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.4 | 4.6 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.4 | 4.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.4 | 1.9 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.4 | 7.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.4 | 1.5 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 0.4 | 18.2 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.3 | 2.7 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.3 | 37.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.3 | 2.9 | GO:0032009 | early phagosome(GO:0032009) |
| 0.3 | 8.1 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.3 | 2.2 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 1.3 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.3 | 2.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.3 | 1.2 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.3 | 1.6 | GO:0036501 | UFD1-NPL4 complex(GO:0036501) |
| 0.3 | 1.5 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.3 | 3.5 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.3 | 2.3 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.3 | 3.4 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.3 | 3.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.3 | 0.8 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.3 | 1.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.3 | 1.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.3 | 1.8 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.3 | 0.5 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.2 | 1.5 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.2 | 18.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 4.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 24.3 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 2.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 3.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.2 | 4.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 3.3 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.2 | 4.1 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.2 | 24.5 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.2 | 85.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.2 | 2.8 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.2 | 1.0 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.2 | 2.8 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.2 | 3.5 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.2 | 6.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.2 | 3.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.2 | 1.1 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.2 | 2.4 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.2 | 2.3 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.2 | 1.0 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.2 | 3.1 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 14.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 2.0 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 1.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 0.5 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 1.3 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 1.7 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.2 | 1.7 | GO:0043219 | lateral loop(GO:0043219) |
| 0.2 | 23.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 1.2 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.1 | 0.9 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 6.1 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.1 | 2.5 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 1.1 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 4.0 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 6.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 3.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 2.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 2.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 0.9 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 1.0 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.1 | 2.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.7 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 14.7 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 2.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 2.1 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.1 | 2.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 2.8 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 2.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 1.0 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 0.1 | 2.4 | GO:0097526 | spliceosomal tri-snRNP complex(GO:0097526) |
| 0.1 | 0.7 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.1 | 1.0 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 1.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 1.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 14.8 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 1.1 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 1.4 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.1 | 32.8 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.1 | 5.1 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 1.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 0.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 19.5 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.1 | 6.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.5 | GO:0043186 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 0.9 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.3 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.1 | 1.8 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 4.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 1.0 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.1 | 3.0 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 3.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.1 | 4.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 1.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.5 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.1 | 0.7 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.0 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.8 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 3.4 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.7 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 2.0 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 0.9 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 2.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.3 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 1.3 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 0.8 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 0.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.2 | GO:0034448 | EGO complex(GO:0034448) |
| 0.0 | 0.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.5 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 8.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 1.0 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 8.1 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 0.5 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.7 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 1.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 5.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 2.4 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 25.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.8 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 5.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.6 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 2.3 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.6 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 4.8 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 2.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 4.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.0 | 0.1 | GO:0019034 | viral replication complex(GO:0019034) host cell nuclear part(GO:0044094) |
| 0.0 | 1.2 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 2.8 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 3.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.7 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 3.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.1 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 0.0 | 0.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 4.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.1 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 3.9 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 2.3 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 2.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.1 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 0.3 | GO:0044815 | DNA packaging complex(GO:0044815) |
| 0.0 | 1.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.2 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 3.2 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 3.4 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.2 | GO:0043596 | nuclear replication fork(GO:0043596) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 13.4 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 4.1 | 44.9 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 3.1 | 9.2 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 2.4 | 9.6 | GO:0019976 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 2.1 | 16.7 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 2.0 | 8.1 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 1.8 | 25.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 1.5 | 33.5 | GO:0005522 | profilin binding(GO:0005522) |
| 1.3 | 3.9 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 1.3 | 7.7 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.2 | 6.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 1.2 | 8.2 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 1.2 | 4.6 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 1.2 | 8.1 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 1.1 | 6.8 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 1.1 | 4.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 1.1 | 30.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 1.0 | 3.1 | GO:0098918 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 1.0 | 7.2 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 1.0 | 3.0 | GO:0016517 | interleukin-12 receptor activity(GO:0016517) |
| 1.0 | 11.6 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 1.0 | 2.9 | GO:0036219 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 0.9 | 3.5 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.8 | 3.3 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 0.8 | 3.3 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.8 | 8.0 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.8 | 2.4 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 0.8 | 4.0 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.8 | 4.6 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.8 | 6.1 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.8 | 3.8 | GO:0017089 | glycolipid transporter activity(GO:0017089) |
| 0.7 | 2.2 | GO:0016603 | glutaminyl-peptide cyclotransferase activity(GO:0016603) |
| 0.7 | 3.7 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.7 | 4.4 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.7 | 2.1 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.7 | 10.0 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.7 | 12.0 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.7 | 3.4 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.7 | 11.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.6 | 3.2 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.6 | 1.9 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.6 | 1.9 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 0.6 | 14.7 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.6 | 2.4 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
| 0.6 | 1.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.6 | 2.3 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.6 | 2.9 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.6 | 3.9 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.6 | 3.3 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.5 | 7.1 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.5 | 2.1 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.5 | 7.9 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.5 | 4.7 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.5 | 20.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.5 | 3.1 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.5 | 2.0 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.5 | 9.9 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.5 | 3.5 | GO:0019862 | IgA binding(GO:0019862) |
| 0.5 | 2.5 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.5 | 2.4 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.5 | 4.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.5 | 2.9 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.5 | 35.5 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.5 | 3.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.5 | 2.9 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.5 | 1.4 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.5 | 4.2 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.5 | 2.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.5 | 3.2 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.5 | 2.3 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.4 | 3.6 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.4 | 4.0 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.4 | 8.5 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.4 | 0.9 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.4 | 1.3 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.4 | 2.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.4 | 1.3 | GO:0031753 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.4 | 3.4 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 0.4 | 1.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.4 | 9.2 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.4 | 2.1 | GO:0042781 | 3'-tRNA processing endoribonuclease activity(GO:0042781) |
| 0.4 | 1.7 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.4 | 1.6 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.4 | 2.8 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.4 | 1.6 | GO:0019958 | C-X-C chemokine binding(GO:0019958) |
| 0.4 | 25.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.4 | 0.8 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 0.4 | 18.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.4 | 1.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.4 | 3.1 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.4 | 1.1 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 0.4 | 12.1 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.4 | 3.4 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.4 | 1.1 | GO:0052858 | peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) |
| 0.4 | 8.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.4 | 6.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.3 | 1.0 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
| 0.3 | 1.7 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.3 | 17.9 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.3 | 4.9 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.3 | 3.9 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.3 | 10.7 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.3 | 1.0 | GO:0016436 | rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (uridine) methyltransferase activity(GO:0016436) |
| 0.3 | 2.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 0.9 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.3 | 10.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.3 | 5.0 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.3 | 20.4 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.3 | 1.1 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 0.3 | 1.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.3 | 10.4 | GO:0022829 | wide pore channel activity(GO:0022829) |
| 0.3 | 2.8 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.3 | 5.8 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.3 | 2.5 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 3.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.3 | 2.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.3 | 18.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.3 | 10.7 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.3 | 2.2 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.3 | 9.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.3 | 4.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.3 | 3.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.3 | 9.5 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.2 | 6.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 3.4 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.2 | 8.4 | GO:0023026 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.2 | 2.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 6.1 | GO:0043495 | protein anchor(GO:0043495) |
| 0.2 | 10.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 1.7 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.2 | 0.8 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.2 | 2.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.2 | 1.9 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.2 | 1.3 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 1.3 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.2 | 0.9 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.2 | 2.4 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 5.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.2 | 12.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 3.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 5.7 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.2 | 3.7 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.2 | 1.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.2 | 3.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.2 | 91.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.2 | 1.8 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 4.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.2 | 1.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 0.8 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.2 | 1.9 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.2 | 1.8 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.2 | 0.9 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.2 | 1.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 5.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.2 | 4.0 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.2 | 2.0 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 1.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.9 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 4.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 1.3 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.1 | 3.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.7 | GO:0004572 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572) |
| 0.1 | 13.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 1.4 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.1 | 1.7 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 0.4 | GO:0048257 | 3'-flap endonuclease activity(GO:0048257) |
| 0.1 | 1.9 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 1.9 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 1.0 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 0.8 | GO:0048256 | flap endonuclease activity(GO:0048256) |
| 0.1 | 1.0 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.1 | 1.4 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.1 | 6.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 1.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 2.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 2.3 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 5.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 2.7 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 0.7 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 8.2 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.9 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.1 | 2.8 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 0.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.5 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 0.5 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.1 | 4.5 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.1 | 4.0 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.4 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.1 | 0.8 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 1.1 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.1 | 3.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.8 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 2.6 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.1 | 0.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 2.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.7 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.1 | 5.1 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.1 | 4.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.7 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 1.5 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 2.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 1.0 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 1.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 3.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.7 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 3.1 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 0.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.6 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 0.6 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 5.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 2.7 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 16.6 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.5 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 1.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 15.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 0.4 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 2.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.1 | 5.4 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.1 | 0.2 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.1 | 0.4 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 1.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 4.6 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
| 0.1 | 1.8 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 0.3 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 2.3 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.4 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.1 | 6.4 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 0.4 | GO:0036080 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.1 | 3.5 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.1 | 0.8 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.1 | 0.2 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.1 | 1.5 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 2.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 2.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.8 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 2.5 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 2.7 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
| 0.1 | 0.4 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 6.4 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.1 | 1.9 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.1 | 0.5 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.1 | 0.9 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 1.0 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 0.5 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.1 | 2.2 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.1 | 0.8 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 0.7 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 1.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.7 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.5 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 6.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.2 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.0 | 18.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 4.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 1.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 3.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 1.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 2.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.7 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.0 | 1.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 13.3 | GO:0005543 | phospholipid binding(GO:0005543) |
| 0.0 | 1.0 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 2.6 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 1.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 1.9 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.0 | 1.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 1.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.1 | GO:0008241 | tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) |
| 0.0 | 9.5 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 2.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.3 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.5 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.6 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
| 0.0 | 0.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.1 | GO:0016429 | tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.2 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
| 0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.4 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.0 | 1.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 0.1 | GO:0003909 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 37.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 1.2 | 122.2 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 1.1 | 72.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.8 | 34.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.6 | 5.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.5 | 13.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.4 | 23.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.4 | 15.6 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.4 | 9.7 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.4 | 34.9 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.4 | 15.2 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.4 | 6.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.3 | 9.4 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.3 | 13.6 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.3 | 34.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.3 | 36.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.3 | 9.0 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.3 | 7.4 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.3 | 12.0 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 8.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.2 | 10.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.2 | 2.6 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.2 | 12.2 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 1.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 2.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.2 | 3.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.2 | 2.0 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.2 | 4.6 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 5.7 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.2 | 5.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.2 | 20.5 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 9.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 8.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 10.3 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 8.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 8.3 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 4.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 1.8 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 11.7 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 5.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 1.0 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.1 | 0.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 1.9 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 4.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.8 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.1 | 0.4 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 2.2 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 5.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 1.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 1.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 2.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 2.1 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 4.9 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 3.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.8 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 1.9 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 2.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 2.6 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 22.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 2.0 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.9 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 4.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.0 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.7 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 4.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 62.4 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 1.2 | 38.2 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.9 | 6.2 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 0.8 | 5.4 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.8 | 88.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.6 | 9.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.6 | 11.7 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.6 | 31.6 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.6 | 2.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.6 | 13.4 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.6 | 24.8 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.5 | 9.7 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.5 | 8.1 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.5 | 19.7 | REACTOME TCR SIGNALING | Genes involved in TCR signaling |
| 0.5 | 6.1 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.5 | 6.0 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.5 | 33.5 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.5 | 0.9 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.5 | 8.4 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.5 | 13.4 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.4 | 6.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.4 | 23.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.4 | 62.8 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.4 | 4.7 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.4 | 5.5 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.4 | 10.7 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.3 | 4.5 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.3 | 3.7 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.3 | 23.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.3 | 8.2 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.3 | 9.0 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.3 | 5.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.3 | 1.6 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.3 | 3.5 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.2 | 6.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.2 | 1.0 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.2 | 4.6 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.2 | 2.3 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.2 | 2.9 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.2 | 12.2 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.2 | 1.7 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.2 | 4.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.2 | 0.8 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.2 | 9.4 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.2 | 4.3 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 1.0 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.2 | 21.4 | REACTOME TOLL RECEPTOR CASCADES | Genes involved in Toll Receptor Cascades |
| 0.2 | 3.2 | REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
| 0.2 | 2.8 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.2 | 6.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 4.3 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.2 | 1.5 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.1 | 1.6 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 24.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.0 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 17.1 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 4.9 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 3.4 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 1.4 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.1 | 5.9 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 9.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 7.1 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.1 | 8.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 4.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 4.1 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.1 | 2.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.0 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 1.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 2.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 2.4 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.1 | 3.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 2.0 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 4.8 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.1 | 2.8 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 5.9 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 12.8 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 2.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 0.7 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 0.4 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.1 | 3.0 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 3.0 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.1 | 1.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 3.0 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 2.0 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.1 | 2.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 3.1 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 0.7 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 0.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 2.5 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 0.4 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.1 | 0.7 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.0 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 0.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 6.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 1.4 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 1.5 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 3.0 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.0 | 3.5 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.7 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 1.0 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.0 | 1.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 1.2 | REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B |
| 0.0 | 1.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.9 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 0.4 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.5 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.5 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.7 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 2.2 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |