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avrg: Illumina Body Map 2 (GSE30611)

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Results for GAGGUAG

Z-value: 1.26

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036
hsa-miR-98-5p
MIMAT0000096

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_188974364 3.05 ENST00000304636.9
ENST00000317840.9
COL3A1
collagen type III alpha 1 chain
chr9_-_127122623 2.84 ENST00000373417.1
ENST00000373425.8
ANGPTL2
angiopoietin like 2
chr17_-_50201618 2.78 ENST00000225964.10
COL1A1
collagen type I alpha 1 chain
chr6_-_53665748 2.67 ENST00000370905.4
KLHL31
kelch like family member 31
chr21_-_26967057 2.60 ENST00000284987.6
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr7_+_94394886 2.46 ENST00000297268.11
ENST00000620463.1
COL1A2
collagen type I alpha 2 chain
chr11_+_78063851 2.16 ENST00000281030.2
THRSP
thyroid hormone responsive
chr9_+_98943898 2.12 ENST00000375001.8
COL15A1
collagen type XV alpha 1 chain
chr5_+_42423433 2.11 ENST00000230882.9
GHR
growth hormone receptor
chr2_-_1744442 2.00 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
PXDN
peroxidasin
chr11_-_86955385 1.91 ENST00000531380.2
FZD4
frizzled class receptor 4
chr13_+_110307276 1.90 ENST00000360467.7
ENST00000650540.1
COL4A2
collagen type IV alpha 2 chain
chr11_+_130448633 1.84 ENST00000299164.4
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
chrX_+_2828808 1.81 ENST00000381163.7
GYG2
glycogenin 2
chr15_+_74173693 1.66 ENST00000249842.8
ISLR
immunoglobulin superfamily containing leucine rich repeat
chr14_+_24398986 1.64 ENST00000382554.4
NYNRIN
NYN domain and retroviral integrase containing
chr15_-_51338575 1.61 ENST00000557858.5
ENST00000558328.5
ENST00000396402.6
ENST00000396404.8
ENST00000561075.5
ENST00000405011.6
ENST00000559980.5
ENST00000453807.6
CYP19A1
cytochrome P450 family 19 subfamily A member 1
chrX_+_105822531 1.57 ENST00000243300.14
ENST00000536164.5
NRK
Nik related kinase
chr8_-_123541197 1.51 ENST00000517956.5
ENST00000443022.2
FBXO32
F-box protein 32
chr1_+_170663134 1.50 ENST00000367760.7
PRRX1
paired related homeobox 1
chr7_-_132576493 1.48 ENST00000321063.8
PLXNA4
plexin A4
chr3_-_86991135 1.47 ENST00000398399.7
VGLL3
vestigial like family member 3
chr17_+_8310220 1.42 ENST00000583529.1
ENST00000361926.8
ARHGEF15
Rho guanine nucleotide exchange factor 15
chr3_+_16174628 1.36 ENST00000339732.10
GALNT15
polypeptide N-acetylgalactosaminyltransferase 15
chr14_-_52069039 1.34 ENST00000216286.10
NID2
nidogen 2
chr3_+_49171590 1.32 ENST00000332780.4
KLHDC8B
kelch domain containing 8B
chr11_-_27472698 1.29 ENST00000389858.4
ENST00000379214.9
LGR4
leucine rich repeat containing G protein-coupled receptor 4
chr8_-_37966582 1.26 ENST00000345060.5
ADRB3
adrenoceptor beta 3
chr4_-_173530219 1.22 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr9_+_106863121 1.22 ENST00000472574.1
ENST00000277225.10
ZNF462
zinc finger protein 462
chr1_+_164559766 1.22 ENST00000367897.5
ENST00000559240.5
PBX1
PBX homeobox 1
chr10_+_71964373 1.22 ENST00000373115.5
CHST3
carbohydrate sulfotransferase 3
chr11_-_10568650 1.16 ENST00000256178.8
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr2_-_189179754 1.16 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr5_-_147453888 1.13 ENST00000398514.7
DPYSL3
dihydropyrimidinase like 3
chr21_-_26845402 1.13 ENST00000284984.8
ENST00000676955.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_+_56645299 1.11 ENST00000371244.9
ENST00000610361.1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
chr9_-_16870662 1.10 ENST00000380672.9
BNC2
basonuclin 2
chr16_+_22206255 1.08 ENST00000263026.10
EEF2K
eukaryotic elongation factor 2 kinase
chr1_-_115338231 1.05 ENST00000369512.3
ENST00000680116.1
ENST00000681124.1
ENST00000675637.2
ENST00000676038.2
NGF
nerve growth factor
chr1_-_91886144 1.05 ENST00000212355.9
TGFBR3
transforming growth factor beta receptor 3
chr9_+_19409000 1.05 ENST00000340967.3
ACER2
alkaline ceramidase 2
chr5_+_38846002 1.05 ENST00000274276.8
OSMR
oncostatin M receptor
chr22_+_23772839 1.01 ENST00000215743.8
MMP11
matrix metallopeptidase 11
chrX_-_33128360 1.00 ENST00000378677.6
DMD
dystrophin
chr1_+_29236544 1.00 ENST00000428026.6
ENST00000460170.2
PTPRU
protein tyrosine phosphatase receptor type U
chr10_-_98268186 0.99 ENST00000260702.4
LOXL4
lysyl oxidase like 4
chr7_-_139036017 0.99 ENST00000275766.2
ZC3HAV1L
zinc finger CCCH-type containing, antiviral 1 like
chr12_-_58919493 0.99 ENST00000379141.8
LRIG3
leucine rich repeats and immunoglobulin like domains 3
chr1_-_9129085 0.98 ENST00000377411.5
GPR157
G protein-coupled receptor 157
chr7_+_90403386 0.97 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
CLDN12
ENSG00000273299.1
claudin 12
novel transcript
chr15_-_82806054 0.96 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chrX_+_56232343 0.95 ENST00000468660.6
KLF8
Kruppel like factor 8
chr18_-_61892997 0.95 ENST00000312828.4
RNF152
ring finger protein 152
chr18_+_6834473 0.89 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
ARHGAP28
Rho GTPase activating protein 28
chr13_-_110307131 0.88 ENST00000543140.6
ENST00000375820.10
COL4A1
collagen type IV alpha 1 chain
chr8_-_13514821 0.87 ENST00000276297.9
DLC1
DLC1 Rho GTPase activating protein
chr2_+_119223815 0.86 ENST00000393106.6
ENST00000393110.7
ENST00000409811.5
ENST00000393107.2
STEAP3
STEAP3 metalloreductase
chr12_-_102480552 0.85 ENST00000337514.11
ENST00000307046.8
IGF1
insulin like growth factor 1
chr22_-_35840218 0.85 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RBFOX2
RNA binding fox-1 homolog 2
chr9_+_114155526 0.84 ENST00000356083.8
COL27A1
collagen type XXVII alpha 1 chain
chr2_-_230068905 0.84 ENST00000457406.5
ENST00000295190.9
SLC16A14
solute carrier family 16 member 14
chr22_-_23751080 0.83 ENST00000341976.5
ZNF70
zinc finger protein 70
chr19_-_48363914 0.83 ENST00000377431.6
ENST00000293261.8
TMEM143
transmembrane protein 143
chr8_-_121641424 0.82 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr5_-_132227808 0.81 ENST00000401867.5
ENST00000379086.5
ENST00000379100.7
ENST00000418055.5
ENST00000453286.5
ENST00000360568.8
ENST00000379104.7
ENST00000166534.8
P4HA2
prolyl 4-hydroxylase subunit alpha 2
chr6_+_41638438 0.79 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr1_-_227947924 0.78 ENST00000272164.6
WNT9A
Wnt family member 9A
chr2_-_157628852 0.77 ENST00000243349.13
ACVR1C
activin A receptor type 1C
chr10_+_100347225 0.76 ENST00000370355.3
SCD
stearoyl-CoA desaturase
chr12_-_68933161 0.74 ENST00000549781.1
ENST00000551568.6
ENST00000548262.5
CPM
carboxypeptidase M
chr15_+_84817346 0.72 ENST00000258888.6
ALPK3
alpha kinase 3
chrX_-_45200828 0.70 ENST00000398000.7
DIPK2B
divergent protein kinase domain 2B
chr19_+_46297032 0.70 ENST00000377670.9
HIF3A
hypoxia inducible factor 3 subunit alpha
chr3_-_69013639 0.68 ENST00000456376.2
ENST00000383701.8
EOGT
EGF domain specific O-linked N-acetylglucosamine transferase
chr7_+_3301242 0.68 ENST00000404826.7
SDK1
sidekick cell adhesion molecule 1
chr12_+_122078740 0.68 ENST00000319080.12
MLXIP
MLX interacting protein
chr13_-_30307539 0.68 ENST00000380615.8
KATNAL1
katanin catalytic subunit A1 like 1
chr11_+_69641146 0.68 ENST00000227507.3
ENST00000536559.1
CCND1
cyclin D1
chr3_-_79019444 0.67 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
ROBO1
roundabout guidance receptor 1
chr3_-_127823177 0.67 ENST00000434178.6
MGLL
monoglyceride lipase
chr1_-_108200335 0.66 ENST00000565488.6
SLC25A24
solute carrier family 25 member 24
chr14_-_34713788 0.66 ENST00000341223.8
CFL2
cofilin 2
chr15_-_65422894 0.66 ENST00000352385.3
IGDCC4
immunoglobulin superfamily DCC subclass member 4
chr4_+_185143258 0.63 ENST00000281456.11
SLC25A4
solute carrier family 25 member 4
chr17_+_40062956 0.63 ENST00000450525.7
THRA
thyroid hormone receptor alpha
chrX_-_118116746 0.63 ENST00000371882.5
ENST00000545703.5
ENST00000540167.5
KLHL13
kelch like family member 13
chr4_+_74933095 0.63 ENST00000513238.5
PARM1
prostate androgen-regulated mucin-like protein 1
chr8_-_69834970 0.62 ENST00000260126.9
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr13_-_33285682 0.62 ENST00000336934.10
STARD13
StAR related lipid transfer domain containing 13
chr3_-_160565560 0.61 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
KPNA4
karyopherin subunit alpha 4
chr2_-_241272812 0.61 ENST00000427007.5
ENST00000458564.5
ENST00000452065.5
ENST00000427183.6
ENST00000426343.5
ENST00000422080.5
ENST00000449504.5
ENST00000449864.5
ENST00000391975.5
HDLBP
high density lipoprotein binding protein
chr16_+_397183 0.61 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr10_+_113854610 0.60 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr22_+_29073024 0.59 ENST00000400335.9
KREMEN1
kringle containing transmembrane protein 1
chr1_-_156082412 0.59 ENST00000532414.3
MEX3A
mex-3 RNA binding family member A
chr9_+_101533840 0.59 ENST00000389120.8
ENST00000374819.6
ENST00000479306.5
RNF20
ring finger protein 20
chr8_+_73294594 0.59 ENST00000240285.10
RDH10
retinol dehydrogenase 10
chr8_+_120125093 0.58 ENST00000297848.8
ENST00000309791.8
COL14A1
collagen type XIV alpha 1 chain
chr2_+_99337364 0.58 ENST00000617677.1
ENST00000289371.11
EIF5B
eukaryotic translation initiation factor 5B
chrX_-_108438407 0.58 ENST00000334504.12
ENST00000621266.4
ENST00000538570.5
ENST00000394872.6
ENST00000545689.2
COL4A6
collagen type IV alpha 6 chain
chr12_+_119593758 0.58 ENST00000426426.3
TMEM233
transmembrane protein 233
chr15_+_36594868 0.58 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDIN1
CDAN1 interacting nuclease 1
chr11_+_114059702 0.57 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
ZBTB16
zinc finger and BTB domain containing 16
chr12_-_56258327 0.56 ENST00000267116.8
ANKRD52
ankyrin repeat domain 52
chr6_+_46652968 0.55 ENST00000371347.10
SLC25A27
solute carrier family 25 member 27
chr4_-_99657820 0.55 ENST00000511828.2
C4orf54
chromosome 4 open reading frame 54
chr22_-_41446777 0.55 ENST00000434408.1
ENST00000327492.4
TOB2
transducer of ERBB2, 2
chr11_+_45847406 0.54 ENST00000443527.6
ENST00000616623.4
ENST00000616080.2
CRY2
cryptochrome circadian regulator 2
chr3_+_172040554 0.54 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr2_+_11534039 0.54 ENST00000381486.7
GREB1
growth regulating estrogen receptor binding 1
chrX_-_133415478 0.53 ENST00000370828.4
GPC4
glypican 4
chr15_-_37098281 0.53 ENST00000559085.5
ENST00000397624.7
MEIS2
Meis homeobox 2
chr16_-_4116403 0.53 ENST00000294016.8
ADCY9
adenylate cyclase 9
chr8_+_22599586 0.53 ENST00000289989.10
ENST00000409586.7
ENST00000614574.4
C8orf58
chromosome 8 open reading frame 58
chr11_+_36567997 0.53 ENST00000299440.6
RAG1
recombination activating 1
chr2_+_32165841 0.51 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
SLC30A6
solute carrier family 30 member 6
chr7_+_16646131 0.50 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
BZW2
basic leucine zipper and W2 domains 2
chr5_-_32312913 0.50 ENST00000280285.9
ENST00000382142.8
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr2_+_74834113 0.50 ENST00000290573.7
HK2
hexokinase 2
chr15_+_57376497 0.50 ENST00000281282.6
CGNL1
cingulin like 1
chr7_-_27165517 0.49 ENST00000396345.1
ENST00000343483.7
HOXA9
homeobox A9
chr1_-_151826085 0.49 ENST00000356728.11
RORC
RAR related orphan receptor C
chr5_-_41510554 0.49 ENST00000377801.8
PLCXD3
phosphatidylinositol specific phospholipase C X domain containing 3
chr11_+_87037820 0.49 ENST00000340353.11
TMEM135
transmembrane protein 135
chr12_-_64752871 0.49 ENST00000418919.6
GNS
glucosamine (N-acetyl)-6-sulfatase
chr8_+_22089140 0.49 ENST00000289921.8
FAM160B2
family with sequence similarity 160 member B2
chr6_-_89412219 0.48 ENST00000369415.9
RRAGD
Ras related GTP binding D
chr12_+_56521798 0.48 ENST00000262031.10
RBMS2
RNA binding motif single stranded interacting protein 2
chr19_-_40690629 0.48 ENST00000252891.8
NUMBL
NUMB like endocytic adaptor protein
chr13_+_98142552 0.48 ENST00000595437.5
FARP1
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr17_+_2055094 0.47 ENST00000399849.4
ENST00000619757.5
HIC1
HIC ZBTB transcriptional repressor 1
chr2_+_219434825 0.47 ENST00000312358.12
SPEG
striated muscle enriched protein kinase
chr10_-_59709842 0.47 ENST00000395348.8
SLC16A9
solute carrier family 16 member 9
chr6_+_36678699 0.47 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
CDKN1A
cyclin dependent kinase inhibitor 1A
chr20_+_58692767 0.46 ENST00000356091.11
NPEPL1
aminopeptidase like 1
chr3_+_184155310 0.46 ENST00000313143.9
DVL3
dishevelled segment polarity protein 3
chr2_+_128091166 0.45 ENST00000259253.11
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr18_+_48539017 0.45 ENST00000256413.8
CTIF
cap binding complex dependent translation initiation factor
chr14_-_75126964 0.45 ENST00000678037.1
ENST00000553823.6
ENST00000678531.1
ENST00000238616.10
NEK9
NIMA related kinase 9
chr7_+_120988683 0.45 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1
chr8_+_69466617 0.45 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
SULF1
sulfatase 1
chr13_-_109786567 0.45 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr14_+_52730154 0.45 ENST00000354586.5
ENST00000442123.6
STYX
serine/threonine/tyrosine interacting protein
chr9_+_125747345 0.45 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX3
PBX homeobox 3
chr12_-_24949026 0.45 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
BCAT1
branched chain amino acid transaminase 1
chr14_+_74881887 0.44 ENST00000334220.9
ENST00000626051.1
ENST00000554806.5
DLST
dihydrolipoamide S-succinyltransferase
chr17_+_9021501 0.44 ENST00000173229.7
NTN1
netrin 1
chr8_-_97277890 0.44 ENST00000322128.5
TSPYL5
TSPY like 5
chr12_+_56118241 0.43 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
ESYT1
ZC3H10
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr3_-_15859771 0.43 ENST00000399451.6
ANKRD28
ankyrin repeat domain 28
chr15_-_50119215 0.43 ENST00000284509.11
ENST00000674213.1
ATP8B4
ATPase phospholipid transporting 8B4 (putative)
chr8_+_27633884 0.43 ENST00000301904.4
SCARA3
scavenger receptor class A member 3
chr5_-_131796921 0.43 ENST00000307968.11
ENST00000307954.12
FNIP1
folliculin interacting protein 1
chr10_+_86756580 0.42 ENST00000372037.8
BMPR1A
bone morphogenetic protein receptor type 1A
chr18_+_21363593 0.42 ENST00000580732.6
GREB1L
GREB1 like retinoic acid receptor coactivator
chr6_+_124962420 0.42 ENST00000521654.7
ENST00000560949.5
RNF217
ring finger protein 217
chr12_+_72272360 0.42 ENST00000547300.2
ENST00000261180.10
TRHDE
thyrotropin releasing hormone degrading enzyme
chr3_-_142225556 0.42 ENST00000392993.7
GK5
glycerol kinase 5
chr2_-_27212256 0.42 ENST00000414408.5
ENST00000310574.8
SLC5A6
solute carrier family 5 member 6
chr1_+_203305510 0.41 ENST00000290551.5
BTG2
BTG anti-proliferation factor 2
chr7_+_130293134 0.40 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
CPA4
carboxypeptidase A4
chr6_+_27388748 0.40 ENST00000244576.9
ZNF391
zinc finger protein 391
chr14_+_55051639 0.40 ENST00000395468.9
ENST00000622254.1
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1 like
chr16_+_70346856 0.40 ENST00000302243.12
ENST00000417604.6
DDX19A
DEAD-box helicase 19A
chr1_-_177969907 0.39 ENST00000308284.10
SEC16B
SEC16 homolog B, endoplasmic reticulum export factor
chr2_-_163735989 0.38 ENST00000333129.4
ENST00000409634.5
FIGN
fidgetin, microtubule severing factor
chr2_+_169733811 0.38 ENST00000392647.7
KLHL23
kelch like family member 23
chr16_+_84648502 0.38 ENST00000564996.6
ENST00000258157.9
ENST00000567410.5
KLHL36
kelch like family member 36
chr9_-_70414657 0.38 ENST00000377126.4
KLF9
Kruppel like factor 9
chr16_-_20900319 0.38 ENST00000564349.5
ENST00000324344.9
ERI2
DCUN1D3
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr1_-_6235945 0.38 ENST00000343813.10
ICMT
isoprenylcysteine carboxyl methyltransferase
chr4_-_86849366 0.38 ENST00000273905.7
SLC10A6
solute carrier family 10 member 6
chr3_+_33114007 0.38 ENST00000320954.11
CRTAP
cartilage associated protein
chrX_+_153334146 0.37 ENST00000370249.3
ENST00000650114.2
ENST00000370251.3
ZNF275
zinc finger protein 275
chr3_-_101320558 0.37 ENST00000193391.8
IMPG2
interphotoreceptor matrix proteoglycan 2
chr20_-_47786553 0.37 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
SULF2
sulfatase 2
chr3_-_48847797 0.37 ENST00000454963.5
ENST00000296446.12
ENST00000419216.1
ENST00000265563.13
PRKAR2A
protein kinase cAMP-dependent type II regulatory subunit alpha
chr1_-_119648165 0.36 ENST00000421812.3
ZNF697
zinc finger protein 697
chr2_-_70994809 0.36 ENST00000272438.9
TEX261
testis expressed 261
chr10_+_70478761 0.36 ENST00000263563.7
PALD1
phosphatase domain containing paladin 1
chr2_+_147845020 0.36 ENST00000241416.12
ACVR2A
activin A receptor type 2A
chr19_-_40348510 0.36 ENST00000582006.5
ENST00000582783.5
C19orf47
chromosome 19 open reading frame 47
chr5_+_62578810 0.36 ENST00000334994.6
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr17_+_43398984 0.36 ENST00000320033.5
ARL4D
ADP ribosylation factor like GTPase 4D
chr2_-_39437264 0.36 ENST00000263881.8
ENST00000341681.9
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr1_-_45206594 0.35 ENST00000359600.6
ZSWIM5
zinc finger SWIM-type containing 5
chr1_+_40783776 0.35 ENST00000347132.10
KCNQ4
potassium voltage-gated channel subfamily Q member 4
chr7_-_138981307 0.35 ENST00000440172.5
ENST00000422774.2
KIAA1549
KIAA1549
chr2_+_66435558 0.34 ENST00000488550.5
MEIS1
Meis homeobox 1
chr5_+_172834225 0.34 ENST00000393784.8
ERGIC1
endoplasmic reticulum-golgi intermediate compartment 1
chr1_+_203626775 0.34 ENST00000367218.7
ATP2B4
ATPase plasma membrane Ca2+ transporting 4
chr5_-_154478218 0.34 ENST00000231121.3
HAND1
heart and neural crest derivatives expressed 1
chr1_+_15617415 0.34 ENST00000480945.6
DDI2
DNA damage inducible 1 homolog 2
chr14_+_55027200 0.34 ENST00000395472.2
ENST00000555846.2
SOCS4
suppressor of cytokine signaling 4
chr1_-_204151884 0.33 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr4_+_82900679 0.33 ENST00000302236.10
THAP9
THAP domain containing 9
chr21_-_44801813 0.33 ENST00000345496.7
UBE2G2
ubiquitin conjugating enzyme E2 G2
chr1_+_64745089 0.33 ENST00000294428.7
ENST00000371072.8
RAVER2
ribonucleoprotein, PTB binding 2
chr11_+_32091065 0.33 ENST00000054950.4
RCN1
reticulocalbin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0044691 tooth eruption(GO:0044691)
0.6 1.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.5 1.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.5 1.6 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.5 1.5 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.4 1.1 GO:0034059 response to anoxia(GO:0034059)
0.4 1.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 3.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.6 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3 1.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.0 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 1.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 0.8 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.3 0.5 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 2.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.2 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 0.8 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.5 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.9 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 2.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.8 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 3.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.4 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.1 0.9 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 1.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.6 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.3 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.7 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.1 0.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 2.0 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of protein lipidation(GO:1903061)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:0003186 tricuspid valve morphogenesis(GO:0003186) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.1 0.6 GO:0015853 adenine transport(GO:0015853)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.4 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.6 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.8 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.1 1.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.2 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.7 GO:0015866 ADP transport(GO:0015866)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.6 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.5 GO:1990253 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.1 2.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 1.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.9 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 2.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 1.0 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.3 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.6 GO:0060431 primary lung bud formation(GO:0060431)
0.0 1.0 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 1.1 GO:0043586 tongue development(GO:0043586)
0.0 1.9 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 1.0 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 2.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 1.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0009650 UV protection(GO:0009650)
0.0 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.6 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 1.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.5 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.7 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.0 GO:0009386 translational attenuation(GO:0009386)
0.0 0.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.4 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.6 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0005584 collagen type I trimer(GO:0005584)
0.7 2.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 5.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 1.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 5.4 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 4.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 10.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 1.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.5 9.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 2.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 1.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.4 1.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.3 1.0 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.3 1.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.3 0.8 GO:0038100 nodal binding(GO:0038100)
0.2 1.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.8 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 3.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 7.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.6 GO:0070330 aromatase activity(GO:0070330)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 4.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.9 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 3.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 8.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID IGF1 PATHWAY IGF1 pathway
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 11.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling