ISMARA results: GLIS2

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avrg: Illumina Body Map 2 (GSE30611)

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Results for GLIS2

Z-value: 2.03

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Transcription factors associated with GLIS2

Gene Symbol	Gene ID	Gene Info
GLIS2 Ensembl NCBI GeneCards UniProt	ENSG00000126603.9	GLIS2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GLIS2	hg38_v1_chr16_+_4316052_4316075	0.21	2.4e-01	Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr20_-_23421409 Show fit	4.44	ENST00000377026.4 ENST00000398425.7 ENST00000432543.6 ENST00000617876.4	NAPB Ensembl NCBI GeneCards UniProt Show fit	NSF attachment protein beta
chr19_+_44905785 Show fit	3.97	ENST00000446996.5 ENST00000252486.9 ENST00000434152.5	APOE Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein E
chr19_+_44914588 Show fit	3.90	ENST00000592535.6	APOC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C1
chr19_+_44914247 Show fit	3.70	ENST00000588750.5 ENST00000588802.5	APOC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C1
chr1_+_160081529 Show fit	3.61	ENST00000368088.4	KCNJ9 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 9
chr7_-_73719629 Show fit	3.56	ENST00000395155.3 ENST00000395154.7 ENST00000395156.7 ENST00000222812.8	STX1A Ensembl NCBI GeneCards UniProt Show fit	syntaxin 1A
chr19_+_44914702 Show fit	3.48	ENST00000592885.5 ENST00000589781.1	APOC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C1
chr16_-_29899532 Show fit	3.27	ENST00000308713.9 ENST00000617533.5	SEZ6L2 Ensembl NCBI GeneCards UniProt Show fit	seizure related 6 homolog like 2
chr19_+_11089446 Show fit	3.25	ENST00000557933.5 ENST00000455727.6 ENST00000535915.5 ENST00000545707.5 ENST00000558518.6 ENST00000558013.5	LDLR Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor
chr16_-_29899043 Show fit	2.97	ENST00000346932.9 ENST00000350527.7 ENST00000568380.1	SEZ6L2 Ensembl NCBI GeneCards UniProt Show fit	seizure related 6 homolog like 2
chr19_+_44914833 Show fit	2.94	ENST00000589078.1 ENST00000586638.5	APOC1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C1
chr20_-_54070520 Show fit	2.88	ENST00000371435.6 ENST00000395961.7	BCAS1 Ensembl NCBI GeneCards UniProt Show fit	brain enriched myelin associated protein 1
chr17_-_7217206 Show fit	2.82	ENST00000447163.6 ENST00000647975.1	DLG4 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr14_+_99684283 Show fit	2.76	ENST00000261835.8	CYP46A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 46 subfamily A member 1
chr14_+_94174284 Show fit	2.65	ENST00000304338.8	PPP4R4 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 4 regulatory subunit 4
chr20_+_46029165 Show fit	2.62	ENST00000616201.4 ENST00000616202.4 ENST00000616933.4 ENST00000626937.2	SLC12A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chrX_-_103064164 Show fit	2.46	ENST00000372728.4	BEX1 Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 1
chrX_+_119236245 Show fit	2.41	ENST00000535419.2	PGRMC1 Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor membrane component 1
chr8_+_27325516 Show fit	2.40	ENST00000346049.10 ENST00000420218.3	PTK2B Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2 beta
chr1_+_2019379 Show fit	2.33	ENST00000638771.1 ENST00000640949.1 ENST00000640030.1	GABRD Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit delta
chrX_+_119236274 Show fit	2.24	ENST00000217971.8	PGRMC1 Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor membrane component 1
chr19_+_55283982 Show fit	2.22	ENST00000309383.6	BRSK1 Ensembl NCBI GeneCards UniProt Show fit	BR serine/threonine kinase 1
chr10_-_102419934 Show fit	2.21	ENST00000406432.5	PSD Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing
chr3_+_154121366 Show fit	2.18	ENST00000465093.6 ENST00000496710.5 ENST00000465817.1	ARHGEF26 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 26
chr22_+_22922594 Show fit	2.18	ENST00000390331.3	IGLC7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 7
chr1_-_16613481 Show fit	2.17	ENST00000430580.6 ENST00000432949.5	NBPF1 Ensembl NCBI GeneCards UniProt Show fit	NBPF member 1
chr19_+_17747698 Show fit	2.03	ENST00000594202.5 ENST00000252771.11	FCHO1 Ensembl NCBI GeneCards UniProt Show fit	FCH and mu domain containing endocytic adaptor 1
chr2_+_24049705 Show fit	2.02	ENST00000380986.9 ENST00000452109.1	FKBP1B Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1B
chr16_-_29899245 Show fit	2.02	ENST00000537485.5	SEZ6L2 Ensembl NCBI GeneCards UniProt Show fit	seizure related 6 homolog like 2
chr20_+_46029206 Show fit	1.99	ENST00000243964.7	SLC12A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr1_+_2019324 Show fit	1.99	ENST00000638411.1 ENST00000378585.7 ENST00000640067.1	GABRD Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit delta
chr19_+_49119531 Show fit	1.98	ENST00000334186.9	PPFIA3 Ensembl NCBI GeneCards UniProt Show fit	PTPRF interacting protein alpha 3
chr19_+_17747737 Show fit	1.96	ENST00000600676.5 ENST00000600209.5 ENST00000596309.5 ENST00000598539.5 ENST00000597474.5 ENST00000593385.5 ENST00000598067.5 ENST00000593833.5	FCHO1 Ensembl NCBI GeneCards UniProt Show fit	FCH and mu domain containing endocytic adaptor 1
chr1_-_57424014 Show fit	1.94	ENST00000371230.1 ENST00000371236.7	DAB1 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 1
chr16_+_30183595 Show fit	1.90	ENST00000219150.10 ENST00000570045.5 ENST00000565497.5 ENST00000570244.5	CORO1A Ensembl NCBI GeneCards UniProt Show fit	coronin 1A
chr12_+_7155867 Show fit	1.82	ENST00000535313.2 ENST00000331148.5	CLSTN3 Ensembl NCBI GeneCards UniProt Show fit	calsyntenin 3
chr1_-_186680411 Show fit	1.80	ENST00000367468.10	PTGS2 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 2
chr19_-_48321857 Show fit	1.79	ENST00000474199.6	ODAD1 Ensembl NCBI GeneCards UniProt Show fit	outer dynein arm docking complex subunit 1
chr10_+_133160194 Show fit	1.79	ENST00000478074.6 ENST00000684248.1 ENST00000304613.8	KNDC1 Ensembl NCBI GeneCards UniProt Show fit	kinase non-catalytic C-lobe domain containing 1
chr5_-_177409535 Show fit	1.79	ENST00000253496.4	F12 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XII
chr6_-_2903300 Show fit	1.78	ENST00000380698.5	SERPINB9 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 9
chr8_-_102124253 Show fit	1.77	ENST00000524209.5 ENST00000517822.5 ENST00000523923.5 ENST00000521599.5 ENST00000521964.5 ENST00000311028.4 ENST00000518166.5	NCALD Ensembl NCBI GeneCards UniProt Show fit	neurocalcin delta
chr19_+_29526499 Show fit	1.75	ENST00000335523.7	VSTM2B Ensembl NCBI GeneCards UniProt Show fit	V-set and transmembrane domain containing 2B
chr2_-_89010515 Show fit	1.71	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr22_+_19719435 Show fit	1.70	ENST00000395109.6	SEPTIN5 Ensembl NCBI GeneCards UniProt Show fit	septin 5
chr11_-_796185 Show fit	1.70	ENST00000533385.5 ENST00000528936.5 ENST00000629634.2 ENST00000625752.2 ENST00000528606.5 ENST00000320230.9	SLC25A22 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 22
chr19_-_821929 Show fit	1.65	ENST00000359894.6 ENST00000520876.8 ENST00000519502.2	PLPPR3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase related 3
chr19_-_48321948 Show fit	1.63	ENST00000674294.1	ODAD1 Ensembl NCBI GeneCards UniProt Show fit	outer dynein arm docking complex subunit 1
chr11_-_1036706 Show fit	1.62	ENST00000421673.7	MUC6 Ensembl NCBI GeneCards UniProt Show fit	mucin 6, oligomeric mucus/gel-forming
chr5_-_1523900 Show fit	1.60	ENST00000283415.4	LPCAT1 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidylcholine acyltransferase 1
chr10_-_133336862 Show fit	1.59	ENST00000368555.3 ENST00000252939.9 ENST00000368558.1	CALY Ensembl NCBI GeneCards UniProt Show fit	calcyon neuron specific vesicular protein
chr4_-_121765104 Show fit	1.59	ENST00000643802.2 ENST00000643663.2	SMIM43 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 43
chrX_+_12791353 Show fit	1.58	ENST00000380663.7 ENST00000398491.6 ENST00000380668.10 ENST00000489404.5	PRPS2 Ensembl NCBI GeneCards UniProt Show fit	phosphoribosyl pyrophosphate synthetase 2
chr8_-_94553444 Show fit	1.53	ENST00000297591.10 ENST00000421249.2	VIRMA Ensembl NCBI GeneCards UniProt Show fit	vir like m6A methyltransferase associated
chr1_+_151721508 Show fit	1.53	ENST00000479191.2	RIIAD1 Ensembl NCBI GeneCards UniProt Show fit	regulatory subunit of type II PKA R-subunit domain containing 1
chr4_-_5019437 Show fit	1.50	ENST00000506508.1 ENST00000509419.1 ENST00000307746.9	CYTL1 Ensembl NCBI GeneCards UniProt Show fit	cytokine like 1
chr5_+_176810552 Show fit	1.49	ENST00000329542.9	UNC5A Ensembl NCBI GeneCards UniProt Show fit	unc-5 netrin receptor A
chr2_+_11612253 Show fit	1.49	ENST00000396123.2	GREB1 Ensembl NCBI GeneCards UniProt Show fit	growth regulating estrogen receptor binding 1
chr7_-_727242 Show fit	1.49	ENST00000537384.6 ENST00000417852.5	PRKAR1B Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit beta
chrX_+_51893533 Show fit	1.48	ENST00000375722.5 ENST00000326587.12 ENST00000375695.2	MAGED1 Ensembl NCBI GeneCards UniProt Show fit	MAGE family member D1
chr15_-_79090760 Show fit	1.47	ENST00000419573.7 ENST00000558480.7	RASGRF1 Ensembl NCBI GeneCards UniProt Show fit	Ras protein specific guanine nucleotide releasing factor 1
chrX_+_53048781 Show fit	1.46	ENST00000332582.5	GPR173 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 173
chr12_+_3491189 Show fit	1.46	ENST00000382622.4	PRMT8 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 8
chr5_-_132777404 Show fit	1.43	ENST00000296873.11	SEPTIN8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr1_+_159171607 Show fit	1.42	ENST00000368124.8 ENST00000368125.9 ENST00000416746.1	CADM3 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule 3
chr20_+_46008900 Show fit	1.42	ENST00000372330.3	MMP9 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 9
chr21_+_33229883 Show fit	1.41	ENST00000382264.7 ENST00000342136.9 ENST00000404220.7	IFNAR2 Ensembl NCBI GeneCards UniProt Show fit	interferon alpha and beta receptor subunit 2
chr2_+_24049673 Show fit	1.40	ENST00000380991.8	FKBP1B Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 1B
chr7_-_712940 Show fit	1.39	ENST00000544935.5 ENST00000430040.5 ENST00000456696.2 ENST00000406797.5	PRKAR1B Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit beta
chr1_-_153375591 Show fit	1.39	ENST00000368737.5	S100A12 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A12
chr7_-_712437 Show fit	1.39	ENST00000360274.8	PRKAR1B Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit beta
chr5_-_132777215 Show fit	1.38	ENST00000458488.2	SEPTIN8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr5_-_132777229 Show fit	1.37	ENST00000378721.8 ENST00000378719.7 ENST00000378701.5	SEPTIN8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr19_+_53909263 Show fit	1.33	ENST00000391767.6	CACNG7 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit gamma 7
chrX_+_153517672 Show fit	1.32	ENST00000349466.6 ENST00000370186.5 ENST00000359149.8	ATP2B3 Ensembl NCBI GeneCards UniProt Show fit	ATPase plasma membrane Ca2+ transporting 3
chr13_-_20192928 Show fit	1.32	ENST00000382848.5	GJB2 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein beta 2
chr14_+_24071552 Show fit	1.31	ENST00000559207.1	CPNE6 Ensembl NCBI GeneCards UniProt Show fit	copine 6
chr19_+_735026 Show fit	1.29	ENST00000592155.5 ENST00000590161.2	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr9_+_113594118 Show fit	1.27	ENST00000620489.1	RGS3 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 3
chr6_+_29657120 Show fit	1.26	ENST00000396704.7 ENST00000416766.6 ENST00000483013.5 ENST00000490427.5 ENST00000376891.8 ENST00000376898.7 ENST00000396701.6 ENST00000494692.5 ENST00000431798.6	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr1_-_169427428 Show fit	1.21	ENST00000456107.1 ENST00000367805.7 ENST00000491570.2	CCDC181 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 181
chr1_-_53945661 Show fit	1.21	ENST00000194214.10	HSPB11 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr6_+_29657085 Show fit	1.20	ENST00000376917.8 ENST00000376894.8	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr17_+_43025203 Show fit	1.19	ENST00000587250.4	RND2 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 2
chr1_-_156705764 Show fit	1.19	ENST00000621784.4 ENST00000368220.1	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr19_+_16720004 Show fit	1.16	ENST00000673803.1 ENST00000549814.5	NWD1 Ensembl NCBI GeneCards UniProt Show fit	NACHT and WD repeat domain containing 1
chr7_-_727611 Show fit	1.13	ENST00000403562.5	PRKAR1B Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit beta
chr16_+_85908988 Show fit	1.12	ENST00000566369.1	IRF8 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 8
chr17_-_5234801 Show fit	1.12	ENST00000571800.5 ENST00000574081.6 ENST00000399600.8 ENST00000574297.1	SCIMP Ensembl NCBI GeneCards UniProt Show fit	SLP adaptor and CSK interacting membrane protein
chr9_+_123033660 Show fit	1.11	ENST00000616002.3	GPR21 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 21
chr17_-_81514629 Show fit	1.11	ENST00000681052.1 ENST00000575659.6	ACTG1 Ensembl NCBI GeneCards UniProt Show fit	actin gamma 1
chr1_-_156705575 Show fit	1.10	ENST00000368222.8	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr21_+_43741420 Show fit	1.10	ENST00000467908.1	PDXK Ensembl NCBI GeneCards UniProt Show fit	pyridoxal kinase
chr5_+_176810498 Show fit	1.09	ENST00000509580.2	UNC5A Ensembl NCBI GeneCards UniProt Show fit	unc-5 netrin receptor A
chr16_-_29923237 Show fit	1.05	ENST00000568995.1 ENST00000566413.1	KCTD13 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 13
chr3_+_38138478 Show fit	1.04	ENST00000396334.8 ENST00000417037.8 ENST00000652213.1 ENST00000650112.2 ENST00000651800.2 ENST00000421516.3 ENST00000650905.2	MYD88 Ensembl NCBI GeneCards UniProt Show fit	MYD88 innate immune signal transduction adaptor
chr1_-_156705742 Show fit	1.04	ENST00000368221.1	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr12_+_50057548 Show fit	1.03	ENST00000228468.8 ENST00000447966.7	ASIC1 Ensembl NCBI GeneCards UniProt Show fit	acid sensing ion channel subunit 1
chr2_-_230068905 Show fit	1.01	ENST00000457406.5 ENST00000295190.9	SLC16A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 14
chr11_-_82845734 Show fit	1.00	ENST00000681883.1 ENST00000680040.1 ENST00000681432.1	PRCP Ensembl NCBI GeneCards UniProt Show fit	prolylcarboxypeptidase
chr3_+_119173564 Show fit	1.00	ENST00000264234.8 ENST00000479520.5 ENST00000494855.5	UPK1B Ensembl NCBI GeneCards UniProt Show fit	uroplakin 1B
chrX_+_153517626 Show fit	1.00	ENST00000263519.5	ATP2B3 Ensembl NCBI GeneCards UniProt Show fit	ATPase plasma membrane Ca2+ transporting 3
chr1_-_1540350 Show fit	0.98	ENST00000624426.1 ENST00000425828.1 ENST00000378733.9	TMEM240 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 240
chr5_-_132777371 Show fit	0.98	ENST00000620483.4	SEPTIN8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr6_+_29656993 Show fit	0.97	ENST00000376888.6	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr17_-_7217178 Show fit	0.96	ENST00000485100.5	DLG4 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr12_-_48957365 Show fit	0.96	ENST00000398092.4 ENST00000539611.1	ENSG00000272822.2 Ensembl NCBI GeneCards UniProt Show fit ARF3 Ensembl NCBI GeneCards UniProt Show fit	novel protein ADP ribosylation factor 3
chr19_+_44751251 Show fit	0.95	ENST00000444487.1	BCL3 Ensembl NCBI GeneCards UniProt Show fit	BCL3 transcription coactivator
chr20_+_46029009 Show fit	0.95	ENST00000608944.5	SLC12A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 5
chr3_+_4493340 Show fit	0.95	ENST00000357086.10 ENST00000354582.12 ENST00000649015.2 ENST00000467056.6	ITPR1 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-trisphosphate receptor type 1
chr17_-_8295342 Show fit	0.95	ENST00000579192.5 ENST00000577745.2	SLC25A35 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 35
chrX_+_103215072 Show fit	0.94	ENST00000372695.6 ENST00000372691.3	BEX4 Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 4
chr22_+_44677077 Show fit	0.94	ENST00000403581.5	PRR5 Ensembl NCBI GeneCards UniProt Show fit	proline rich 5
chr1_-_6490564 Show fit	0.93	ENST00000377725.5 ENST00000340850.10	PLEKHG5 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and RhoGEF domain containing G5
chr16_+_70646536 Show fit	0.93	ENST00000288098.6	IL34 Ensembl NCBI GeneCards UniProt Show fit	interleukin 34
chr12_-_121669646 Show fit	0.93	ENST00000355329.7	MORN3 Ensembl NCBI GeneCards UniProt Show fit	MORN repeat containing 3
chr2_+_86907953 Show fit	0.93	ENST00000409776.6	RGPD1 Ensembl NCBI GeneCards UniProt Show fit	RANBP2 like and GRIP domain containing 1
chr2_-_208254232 Show fit	0.92	ENST00000415913.5 ENST00000415282.5 ENST00000446179.5	IDH1 Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chr2_+_37344594 Show fit	0.92	ENST00000404976.5 ENST00000338415.8	QPCT Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-peptide cyclotransferase
chr20_+_54208072 Show fit	0.92	ENST00000371419.7	PFDN4 Ensembl NCBI GeneCards UniProt Show fit	prefoldin subunit 4
chrX_-_103832204 Show fit	0.91	ENST00000674363.1 ENST00000674162.1 ENST00000674338.1 ENST00000674274.1 ENST00000674271.1 ENST00000674265.1 ENST00000674212.1 ENST00000674255.1 ENST00000674342.1 ENST00000674430.1 ENST00000243298.3	ENSG00000288597.1 Ensembl NCBI GeneCards UniProt Show fit RAB9B Ensembl NCBI GeneCards UniProt Show fit	novel transcript RAB9B, member RAS oncogene family
chr14_-_106211453 Show fit	0.91	ENST00000390606.3	IGHV3-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-20
chr6_-_43016856 Show fit	0.89	ENST00000645375.1 ENST00000645410.1	MEA1 Ensembl NCBI GeneCards UniProt Show fit	male-enhanced antigen 1
chr6_+_33080445 Show fit	0.89	ENST00000428835.5	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr13_-_94596145 Show fit	0.89	ENST00000261296.7	TGDS Ensembl NCBI GeneCards UniProt Show fit	TDP-glucose 4,6-dehydratase
chr1_-_169427408 Show fit	0.88	ENST00000367806.7	CCDC181 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 181
chr9_+_114611206 Show fit	0.88	ENST00000374049.4 ENST00000288502.9	TMEM268 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 268
chr7_+_2656092 Show fit	0.87	ENST00000429448.1	TTYH3 Ensembl NCBI GeneCards UniProt Show fit	tweety family member 3
chr1_-_28193873 Show fit	0.87	ENST00000305392.3 ENST00000539896.1	PTAFR Ensembl NCBI GeneCards UniProt Show fit	platelet activating factor receptor
chr5_-_132777866 Show fit	0.87	ENST00000448933.5	SEPTIN8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr3_+_4493442 Show fit	0.86	ENST00000456211.8 ENST00000443694.5 ENST00000648266.1	ITPR1 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-trisphosphate receptor type 1
chr7_+_101154981 Show fit	0.85	ENST00000646560.1	AP1S1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 1
chr2_+_98087160 Show fit	0.85	ENST00000477737.6	VWA3B Ensembl NCBI GeneCards UniProt Show fit	von Willebrand factor A domain containing 3B
chr11_-_82846128 Show fit	0.84	ENST00000679809.1 ENST00000680186.1 ENST00000681592.1	PRCP Ensembl NCBI GeneCards UniProt Show fit	prolylcarboxypeptidase
chr1_+_43172324 Show fit	0.83	ENST00000528956.5 ENST00000610710.4 ENST00000372492.9 ENST00000529956.5	CFAP57 Ensembl NCBI GeneCards UniProt Show fit	cilia and flagella associated protein 57
chr22_+_44677044 Show fit	0.82	ENST00000006251.11	PRR5 Ensembl NCBI GeneCards UniProt Show fit	proline rich 5
chr3_-_183427977 Show fit	0.82	ENST00000473233.5	MCF2L2 Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence-like 2
chr17_-_39864140 Show fit	0.82	ENST00000623724.3 ENST00000439167.6 ENST00000377945.7 ENST00000394189.6 ENST00000377944.7 ENST00000377958.6 ENST00000535189.5 ENST00000377952.6	IKZF3 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 3
chr11_-_72642407 Show fit	0.82	ENST00000376450.7	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr20_+_37346128 Show fit	0.82	ENST00000373578.7	SRC Ensembl NCBI GeneCards UniProt Show fit	SRC proto-oncogene, non-receptor tyrosine kinase
chr2_-_24123251 Show fit	0.81	ENST00000313213.5 ENST00000436622.1	PFN4 Ensembl NCBI GeneCards UniProt Show fit	profilin family member 4
chr11_-_63917129 Show fit	0.81	ENST00000301459.5	RCOR2 Ensembl NCBI GeneCards UniProt Show fit	REST corepressor 2
chr9_+_136945234 Show fit	0.80	ENST00000371634.7	C8G Ensembl NCBI GeneCards UniProt Show fit	complement C8 gamma chain
chr3_-_149086488 Show fit	0.80	ENST00000392912.6 ENST00000465259.5 ENST00000310053.10 ENST00000494055.5	HLTF Ensembl NCBI GeneCards UniProt Show fit	helicase like transcription factor
chr11_-_72642450 Show fit	0.80	ENST00000444035.6 ENST00000544570.5	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr14_-_56810380 Show fit	0.79	ENST00000672125.1 ENST00000673481.1	OTX2 Ensembl NCBI GeneCards UniProt Show fit	orthodenticle homeobox 2
chr19_-_18896081 Show fit	0.78	ENST00000429504.6 ENST00000623882.4 ENST00000247005.8	CERS1 Ensembl NCBI GeneCards UniProt Show fit GDF1 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 1 growth differentiation factor 1
chr17_-_7178116 Show fit	0.77	ENST00000380920.8	ASGR1 Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 1
chr17_+_66835110 Show fit	0.77	ENST00000533854.6	CACNG5 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit gamma 5
chr16_+_283157 Show fit	0.77	ENST00000219406.11 ENST00000404312.5 ENST00000456379.1	PDIA2 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 2
chr11_-_76669985 Show fit	0.77	ENST00000407242.6 ENST00000421973.1	LRRC32 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 32
chr22_+_50674879 Show fit	0.76	ENST00000262795.6	SHANK3 Ensembl NCBI GeneCards UniProt Show fit	SH3 and multiple ankyrin repeat domains 3
chr19_-_6720641 Show fit	0.76	ENST00000245907.11	C3 Ensembl NCBI GeneCards UniProt Show fit	complement C3
chr22_+_44676808 Show fit	0.76	ENST00000624862.3	PRR5 Ensembl NCBI GeneCards UniProt Show fit	proline rich 5
chr22_+_50738198 Show fit	0.76	ENST00000216139.10 ENST00000529621.1	ACR Ensembl NCBI GeneCards UniProt Show fit	acrosin
chr12_-_50167292 Show fit	0.75	ENST00000547800.2 ENST00000317551.12 ENST00000422340.6	CERS5 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 5
chr8_+_38386433 Show fit	0.75	ENST00000297720.9 ENST00000524874.5 ENST00000379957.9 ENST00000523983.6	LETM2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper and EF-hand containing transmembrane protein 2
chr10_+_132186937 Show fit	0.75	ENST00000338492.9	DPYSL4 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 4
chr6_+_68635273 Show fit	0.74	ENST00000370598.6	ADGRB3 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor B3
chr11_+_121576760 Show fit	0.74	ENST00000532694.5 ENST00000534286.5	SORL1 Ensembl NCBI GeneCards UniProt Show fit	sortilin related receptor 1
chr16_+_88382950 Show fit	0.74	ENST00000565624.3	ZNF469 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 469
chr1_-_53945584 Show fit	0.74	ENST00000371377.3	HSPB11 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 11
chr19_+_48325323 Show fit	0.73	ENST00000596315.5	EMP3 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 3
chr19_-_54339146 Show fit	0.73	ENST00000291759.5	LILRA4 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A4
chr16_-_17470953 Show fit	0.72	ENST00000261381.7	XYLT1 Ensembl NCBI GeneCards UniProt Show fit	xylosyltransferase 1
chr6_+_84033717 Show fit	0.72	ENST00000257776.5	MRAP2 Ensembl NCBI GeneCards UniProt Show fit	melanocortin 2 receptor accessory protein 2
chr19_+_1905366 Show fit	0.72	ENST00000414057.6 ENST00000316097.13 ENST00000409472.5 ENST00000329478.4	SCAMP4 Ensembl NCBI GeneCards UniProt Show fit ADAT3 Ensembl NCBI GeneCards UniProt Show fit	secretory carrier membrane protein 4 adenosine deaminase tRNA specific 3
chr3_+_4493471 Show fit	0.72	ENST00000544951.6 ENST00000650294.1	ITPR1 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-trisphosphate receptor type 1
chr10_-_133424572 Show fit	0.71	ENST00000414069.2	SPRN Ensembl NCBI GeneCards UniProt Show fit	shadow of prion protein
chr14_+_104924713 Show fit	0.71	ENST00000649344.1 ENST00000540372.5	PLD4 Ensembl NCBI GeneCards UniProt Show fit	phospholipase D family member 4
chr6_+_162727129 Show fit	0.71	ENST00000337019.7 ENST00000366889.6	PACRG Ensembl NCBI GeneCards UniProt Show fit	parkin coregulated
chr1_+_202010575 Show fit	0.71	ENST00000367283.7 ENST00000367284.10	ELF3 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 3
chr9_+_132161672 Show fit	0.70	ENST00000372179.7	NTNG2 Ensembl NCBI GeneCards UniProt Show fit	netrin G2
chr8_+_41490396 Show fit	0.69	ENST00000518270.5 ENST00000520817.5	GOLGA7 Ensembl NCBI GeneCards UniProt Show fit	golgin A7
chr8_+_97869040 Show fit	0.68	ENST00000254898.7 ENST00000524308.5 ENST00000522025.6	MATN2 Ensembl NCBI GeneCards UniProt Show fit	matrilin 2
chr21_+_33403391 Show fit	0.67	ENST00000290219.11 ENST00000381995.5	IFNGR2 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr19_+_54593619 Show fit	0.65	ENST00000251372.8 ENST00000453777.1	LILRA1 Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A1
chr1_-_231040218 Show fit	0.65	ENST00000366654.5	FAM89A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 89 member A
chr1_+_1632152 Show fit	0.64	ENST00000472264.1 ENST00000356026.10 ENST00000378675.7	MMP23B Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 23B
chr8_+_98032249 Show fit	0.64	ENST00000522135.5	MATN2 Ensembl NCBI GeneCards UniProt Show fit	matrilin 2
chr16_+_28494634 Show fit	0.63	ENST00000564831.6 ENST00000431282.2	APOBR Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B receptor
chr4_+_151099637 Show fit	0.63	ENST00000512690.5 ENST00000508783.5 ENST00000512797.5 ENST00000507327.5 ENST00000515792.5 ENST00000506126.5	RPS3A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S3A
chr7_-_130441136 Show fit	0.62	ENST00000675596.1 ENST00000676312.1	CEP41 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 41
chr22_-_31630805 Show fit	0.61	ENST00000266095.9	PISD Ensembl NCBI GeneCards UniProt Show fit	phosphatidylserine decarboxylase
chr19_-_38617928 Show fit	0.60	ENST00000396857.7 ENST00000586296.5	MAP4K1 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 1
chr19_+_53869384 Show fit	0.60	ENST00000391769.2	MYADM Ensembl NCBI GeneCards UniProt Show fit	myeloid associated differentiation marker
chr17_-_41836260 Show fit	0.60	ENST00000521789.5	NT5C3B Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase, cytosolic IIIB
chr2_-_178478541 Show fit	0.60	ENST00000424785.7	FKBP7 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 7
chr14_+_104924843 Show fit	0.60	ENST00000557573.1 ENST00000392593.9	PLD4 Ensembl NCBI GeneCards UniProt Show fit	phospholipase D family member 4
chr19_-_42427379 Show fit	0.60	ENST00000244289.9	LIPE Ensembl NCBI GeneCards UniProt Show fit	lipase E, hormone sensitive type
chr1_-_155978144 Show fit	0.60	ENST00000313695.11 ENST00000497907.5	ARHGEF2 Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr5_+_69492767 Show fit	0.59	ENST00000681041.1 ENST00000680098.1 ENST00000680784.1 ENST00000396442.7 ENST00000681895.1	OCLN Ensembl NCBI GeneCards UniProt Show fit	occludin
chr6_-_33192454 Show fit	0.59	ENST00000395194.1 ENST00000341947.7 ENST00000374708.8	COL11A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type XI alpha 2 chain
chr4_+_151099584 Show fit	0.59	ENST00000509736.5 ENST00000505243.5 ENST00000274065.9 ENST00000514682.5 ENST00000503002.5	RPS3A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S3A
chr9_+_131009141 Show fit	0.59	ENST00000361069.9	LAMC3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 3
chr15_+_28919367 Show fit	0.58	ENST00000558804.5	APBA2 Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family A member 2
chr21_-_32585496 Show fit	0.58	ENST00000674156.1 ENST00000300258.8 ENST00000673699.1	TCP10L Ensembl NCBI GeneCards UniProt Show fit	t-complex 10 like
chr3_-_9952337 Show fit	0.58	ENST00000411976.2 ENST00000412055.6	PRRT3 Ensembl NCBI GeneCards UniProt Show fit	proline rich transmembrane protein 3
chr14_+_103100144 Show fit	0.58	ENST00000380069.7	EXOC3L4 Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 3 like 4
chr2_-_135876382 Show fit	0.57	ENST00000264156.3	MCM6 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	14.0	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
1.4	5.6	GO:0040040	thermosensory behavior(GO:0040040)
1.3	4.0	GO:2000646	lipid transport involved in lipid storage(GO:0010877) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.8	3.3	GO:0010899	regulation of phosphatidylcholine catabolic process(GO:0010899)
0.6	1.8	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6	3.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.5	4.4	GO:0035494	SNARE complex disassembly(GO:0035494)
0.5	1.9	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.4	1.8	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4	1.8	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.4	1.3	GO:0031104	dendrite regeneration(GO:0031104)
0.4	2.4	GO:2000538	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4	1.9	GO:0032796	uropod organization(GO:0032796)
0.3	1.0	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.3	1.6	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3	0.9	GO:0006097	glyoxylate cycle(GO:0006097)
0.3	1.5	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3	0.9	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3	0.9	GO:0014810	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.3	1.5	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.3	2.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.3	4.6	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.3	1.8	GO:0002353	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.3	0.8	GO:0072720	response to dithiothreitol(GO:0072720)
0.3	0.8	GO:0001796	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of activation of membrane attack complex(GO:0001970) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.3	4.8	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.3	2.8	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2	0.7	GO:1905246	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2	5.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2	3.4	GO:0061179	positive regulation of axon regeneration(GO:0048680) negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	0.9	GO:0009443	pyridoxal 5'-phosphate salvage(GO:0009443)
0.2	1.6	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2	2.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.2	1.3	GO:0044752	response to human chorionic gonadotropin(GO:0044752)
0.2	0.6	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.2	1.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.2	0.9	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2	1.0	GO:0050915	sensory perception of sour taste(GO:0050915)
0.2	2.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.2	0.5	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.2	0.8	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.2	1.8	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2	1.3	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2	1.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	1.8	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.1	1.4	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.1	0.5	GO:0014028	notochord formation(GO:0014028)
0.1	0.5	GO:0045659	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	5.6	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	2.5	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.8	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	0.5	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.4	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1	0.5	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.1	0.6	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1	1.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1	0.9	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	0.4	GO:2000196	positive regulation of female gonad development(GO:2000196)
0.1	0.3	GO:0099538	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1	0.7	GO:0099558	maintenance of synapse structure(GO:0099558)
0.1	2.5	GO:0070986	left/right axis specification(GO:0070986)
0.1	0.6	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	0.4	GO:0031117	osmosensory signaling pathway(GO:0007231) positive regulation of microtubule depolymerization(GO:0031117)
0.1	0.3	GO:2000656	regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1	0.4	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.1	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.6	GO:0060023	soft palate development(GO:0060023)
0.1	2.0	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	2.1	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	3.0	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.2	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.1	1.2	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.5	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1	0.8	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.5	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.1	0.8	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.4	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.1	0.8	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.1	0.6	GO:0070673	response to interleukin-18(GO:0070673)
0.1	0.2	GO:0034371	chylomicron remodeling(GO:0034371)
0.1	0.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	1.6	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.3	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.8	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.1	1.5	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1	2.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.3	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.3	GO:0097680	immunoglobulin V(D)J recombination(GO:0033152) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0060032	notochord regression(GO:0060032)
0.0	0.6	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.5	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.6	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	1.7	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.4	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.5	GO:0036371	protein localization to T-tubule(GO:0036371)
0.0	0.6	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	1.7	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.9	GO:0045657	positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
0.0	0.4	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	1.2	GO:0032060	bleb assembly(GO:0032060)
0.0	1.1	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.7	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:1903413	cellular response to bile acid(GO:1903413)
0.0	0.3	GO:1900377	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	1.7	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.4	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.6	GO:0051601	exocyst localization(GO:0051601)
0.0	2.6	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.2	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	2.7	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	2.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.9	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.2	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.2	GO:0075044	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0	1.8	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:1902303	negative regulation of potassium ion export(GO:1902303) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0	0.2	GO:0015798	myo-inositol transport(GO:0015798)
0.0	0.5	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.3	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.4	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.3	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.9	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.0	1.3	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	1.3	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	2.8	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	1.1	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.9	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	1.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.4	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	3.5	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.5	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	1.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	3.3	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.3	GO:0015884	folic acid transport(GO:0015884)
0.0	1.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.8	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0015692	lead ion transport(GO:0015692)
0.0	0.2	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.8	GO:0035767	endothelial cell chemotaxis(GO:0035767)
0.0	0.6	GO:0031297	replication fork processing(GO:0031297)
0.0	1.4	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	1.3	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.5	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	2.2	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.9	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.5	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	1.1	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.3	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	1.3	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.4	GO:0051984	positive regulation of chromosome segregation(GO:0051984)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.3	GO:1990666	PCSK9-LDLR complex(GO:1990666)
1.0	4.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.7	3.6	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.5	14.7	GO:0042627	chylomicron(GO:0042627)
0.4	2.0	GO:1990742	microvesicle(GO:1990742)
0.4	1.6	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.3	2.1	GO:0002177	manchette(GO:0002177)
0.3	0.8	GO:0043159	acrosomal matrix(GO:0043159)
0.2	1.0	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.2	2.5	GO:0005955	calcineurin complex(GO:0005955)
0.2	5.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.2	3.8	GO:0098839	postsynaptic density membrane(GO:0098839)
0.2	0.6	GO:0005592	collagen type XI trimer(GO:0005592)
0.1	0.6	GO:0035101	FACT complex(GO:0035101)
0.1	2.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	2.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.9	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.4	GO:0008537	proteasome activator complex(GO:0008537)
0.1	4.3	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	0.4	GO:0070701	mucus layer(GO:0070701)
0.1	2.5	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.8	GO:0005579	membrane attack complex(GO:0005579)
0.1	1.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.5	GO:0048179	activin receptor complex(GO:0048179)
0.1	5.5	GO:0031201	SNARE complex(GO:0031201)
0.1	1.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	1.1	GO:0097433	dense body(GO:0097433)
0.1	2.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	1.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	0.7	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	0.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1	2.7	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.3	GO:0097449	astrocyte projection(GO:0097449)
0.0	4.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	1.9	GO:0001891	phagocytic cup(GO:0001891)
0.0	2.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	2.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.7	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.7	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.7	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.6	GO:0042555	MCM complex(GO:0042555)
0.0	3.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	1.7	GO:0002080	acrosomal membrane(GO:0002080)
0.0	1.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.3	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	3.0	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	2.2	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	2.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	2.3	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	4.0	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	4.7	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	1.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	1.4	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.7	GO:0035869	ciliary transition zone(GO:0035869)
0.0	2.2	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	3.0	GO:0005901	caveola(GO:0005901)
0.0	0.9	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.9	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	1.9	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.6	GO:0005605	basal lamina(GO:0005605)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	1.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	1.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	4.1	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	18.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.1	4.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.6	3.4	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5	3.9	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.5	2.4	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4	1.6	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4	3.8	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.4	1.5	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.4	1.8	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3	5.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3	2.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	0.9	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.3	0.9	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3	1.4	GO:0004905	type I interferon receptor activity(GO:0004905)
0.3	1.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.3	1.6	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.2	0.7	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.2	0.7	GO:0031780	corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2	3.6	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.2	4.0	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.2	5.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2	0.9	GO:0008478	pyridoxal kinase activity(GO:0008478)
0.2	1.3	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.2	1.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.2	1.0	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.2	0.6	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.2	0.8	GO:0004040	amidase activity(GO:0004040)
0.2	4.1	GO:0019841	retinol binding(GO:0019841)
0.2	0.5	GO:0097258	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2	4.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	1.7	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.1	0.9	GO:0050610	glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1	0.9	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.4	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.5	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1	0.9	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	1.6	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	1.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1	1.6	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	1.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.7	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.8	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.3	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	4.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.1	1.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.6	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0001626	nociceptin receptor activity(GO:0001626)
0.1	0.6	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.1	0.8	GO:0071253	connexin binding(GO:0071253)
0.1	0.5	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.1	1.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.6	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.6	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	1.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	2.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	0.2	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	1.8	GO:0051787	misfolded protein binding(GO:0051787)
0.1	1.0	GO:0005243	gap junction channel activity(GO:0005243)
0.1	2.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.5	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	1.9	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.9	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	1.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.5	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.8	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	2.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	2.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.6	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0035473	lipase binding(GO:0035473)
0.0	0.4	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	2.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	2.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.9	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	1.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	1.1	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.7	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	1.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	1.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0	7.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	4.6	GO:0020037	heme binding(GO:0020037)
0.0	0.1	GO:0090541	MIT domain binding(GO:0090541)
0.0	0.4	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	2.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.7	GO:0031005	filamin binding(GO:0031005)
0.0	2.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.4	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	3.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	1.1	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	1.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0008160	protein tyrosine phosphatase activator activity(GO:0008160)
0.0	0.5	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.9	GO:0042605	peptide antigen binding(GO:0042605)
0.0	1.0	GO:0005123	death receptor binding(GO:0005123)
0.0	1.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.8	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.6	GO:0030553	cGMP binding(GO:0030553)
0.0	1.6	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	1.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.8	GO:0019239	deaminase activity(GO:0019239)
0.0	1.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	2.0	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.6	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.9	GO:0016836	hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	8.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	2.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	2.8	PID REELIN PATHWAY	Reelin signaling pathway
0.0	1.4	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	6.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.9	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	1.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	2.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.9	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.0	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	4.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	2.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	4.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	3.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	5.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	3.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	4.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	1.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	1.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	4.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	2.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	2.0	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Results for GLIS2

Z-value: 2.03

Motif logo

Transcription factors associated with GLIS2

Activity-expression correlation:

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: