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avrg: Illumina Body Map 2 (GSE30611)

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Results for HES7_HES5

Z-value: 1.36

Motif logo

Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
ENSG00000179111.9 HES7
ENSG00000197921.6 HES5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES5hg38_v1_chr1_-_2530256_25302700.345.7e-02Click!
HES7hg38_v1_chr17_-_8124084_81241140.202.7e-01Click!

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_25906411 8.75 ENST00000455785.7
stathmin 1
chr1_-_25906931 8.31 ENST00000357865.6
stathmin 1
chr1_-_25906457 7.64 ENST00000426559.6
stathmin 1
chr1_-_25905989 7.46 ENST00000399728.5
stathmin 1
chr14_-_77271200 3.43 ENST00000298352.5
neuroglobin
chr19_+_4304588 3.28 ENST00000221856.11
fibronectin type III and SPRY domain containing 1
chr4_-_6200520 2.96 ENST00000409021.9
ENST00000409371.8
ENST00000282924.9
ENST00000531445.3
janus kinase and microtubule interacting protein 1
chromosome 4 open reading frame 50
chr11_+_125904467 2.93 ENST00000263576.11
ENST00000530414.5
ENST00000530129.6
DEAD-box helicase 25
chr1_+_15756659 2.81 ENST00000375771.5
filamin binding LIM protein 1
chr14_+_65412717 2.79 ENST00000673929.1
fucosyltransferase 8
chr19_+_4304632 2.67 ENST00000597590.5
fibronectin type III and SPRY domain containing 1
chr5_+_153490655 2.58 ENST00000518142.5
ENST00000285900.10
glutamate ionotropic receptor AMPA type subunit 1
chr9_+_68705414 2.34 ENST00000541509.5
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr14_+_65412949 2.24 ENST00000674118.1
ENST00000553924.5
ENST00000358307.6
ENST00000557338.5
ENST00000554610.1
fucosyltransferase 8
chr4_-_52656536 2.00 ENST00000508499.5
ubiquitin specific peptidase 46
chr13_+_34942263 1.93 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr1_+_239386942 1.89 ENST00000675184.1
cholinergic receptor muscarinic 3
chrX_+_134990980 1.80 ENST00000330288.6
small integral membrane protein 10
chr2_-_27264083 1.73 ENST00000432351.5
solute carrier family 30 member 3
chr5_+_176810498 1.70 ENST00000509580.2
unc-5 netrin receptor A
chr5_+_176810552 1.67 ENST00000329542.9
unc-5 netrin receptor A
chr5_+_153490727 1.62 ENST00000340592.9
glutamate ionotropic receptor AMPA type subunit 1
chr1_+_239386556 1.61 ENST00000676153.1
cholinergic receptor muscarinic 3
chr1_-_6180265 1.60 ENST00000262450.8
chromodomain helicase DNA binding protein 5
chr3_-_190122317 1.58 ENST00000427335.6
prolyl 3-hydroxylase 2
chr11_+_60429567 1.52 ENST00000300190.7
membrane spanning 4-domains A5
chr17_+_41930599 1.52 ENST00000377540.6
outer dynein arm docking complex subunit 4
chr1_+_166989254 1.50 ENST00000367872.9
ENST00000447624.1
maelstrom spermatogenic transposon silencer
chr1_-_166975407 1.44 ENST00000528703.5
ENST00000525740.5
ENST00000529387.5
ENST00000469934.6
ENST00000529071.5
ENST00000526687.1
ENST00000271417.8
immunoglobulin like domain containing receptor 2
chr16_-_5065911 1.41 ENST00000472572.8
ENST00000474471.7
chromosome 16 open reading frame 89
chr12_+_102957666 1.40 ENST00000266744.4
achaete-scute family bHLH transcription factor 1
chr17_-_17206264 1.38 ENST00000321560.4
phospholipase D family member 6
chr1_+_150282526 1.28 ENST00000447007.5
ENST00000369095.5
ENST00000369094.5
ENST00000290363.6
circadian associated repressor of transcription
chrX_-_20141810 1.28 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr19_+_12995554 1.28 ENST00000397661.6
nuclear factor I X
chr1_+_15756603 1.27 ENST00000496928.6
ENST00000508310.5
filamin binding LIM protein 1
chr11_+_35662739 1.23 ENST00000299413.7
tripartite motif containing 44
chr7_+_118214633 1.21 ENST00000477532.5
ankyrin repeat domain 7
chr2_-_132161952 1.19 ENST00000409867.6
ankyrin repeat domain 30B like
chr4_-_170003738 1.18 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr13_+_79481124 1.15 ENST00000612570.4
ENST00000218652.11
Nedd4 family interacting protein 2
chr5_-_55233586 1.11 ENST00000282572.5
cyclin O
chr6_+_122610391 1.11 ENST00000368452.7
cAMP-dependent protein kinase inhibitor beta
chr19_-_3700390 1.07 ENST00000679885.1
ENST00000537021.1
ENST00000589578.5
ENST00000539785.5
ENST00000335312.8
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
chr2_-_2326161 1.07 ENST00000649810.1
ENST00000648318.1
myelin transcription factor 1 like
chr11_+_35618450 1.07 ENST00000317811.6
four-jointed box kinase 1
chrX_+_153056458 1.06 ENST00000593810.3
PNMA family member 3
chr22_-_50085414 1.05 ENST00000311597.10
modulator of VRAC current 1
chr3_+_38496329 1.04 ENST00000287675.10
ENST00000630638.1
ENST00000422077.6
exo/endonuclease G
chr1_+_15756628 1.04 ENST00000510393.5
ENST00000430076.5
filamin binding LIM protein 1
chrX_+_153056408 1.02 ENST00000619635.1
PNMA family member 3
chr22_-_50085331 1.02 ENST00000395876.6
modulator of VRAC current 1
chr3_-_183825513 1.01 ENST00000318631.8
ENST00000431348.1
MAP6 domain containing 1
chr14_-_67359769 1.01 ENST00000555431.5
ENST00000554236.5
ENST00000555474.5
ENST00000216442.12
ATPase H+ transporting V1 subunit D
chr14_+_24171853 0.99 ENST00000620473.4
ENST00000557806.5
ENST00000611366.5
REC8 meiotic recombination protein
chr12_-_90955172 0.97 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr13_+_79481468 0.97 ENST00000620924.1
Nedd4 family interacting protein 2
chr15_+_68578970 0.96 ENST00000261861.10
coronin 2B
chr1_-_66924791 0.96 ENST00000371023.7
ENST00000371022.3
ENST00000371026.8
dynein axonemal intermediate chain 4
chr14_+_93918889 0.95 ENST00000557719.1
ENST00000267594.5
family with sequence similarity 181 member A
chr17_-_44830774 0.94 ENST00000590758.3
ENST00000591424.5
gap junction protein gamma 1
chr16_+_283157 0.94 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr13_+_79481446 0.93 ENST00000487865.5
Nedd4 family interacting protein 2
chr10_+_134465 0.93 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chrX_+_40623423 0.90 ENST00000423387.4
mitochondrial pyruvate carrier 1 like
chr5_+_144170843 0.87 ENST00000512467.6
potassium channel tetramerization domain containing 16
chr20_+_46894581 0.86 ENST00000357410.7
ENST00000611592.4
EYA transcriptional coactivator and phosphatase 2
chr20_+_46894824 0.86 ENST00000327619.10
ENST00000497062.6
EYA transcriptional coactivator and phosphatase 2
chr16_+_84175933 0.84 ENST00000569735.1
dynein axonemal assembly factor 1
chrX_+_134460138 0.82 ENST00000298556.8
hypoxanthine phosphoribosyltransferase 1
chr1_+_43991769 0.82 ENST00000466180.1
coiled-coil domain containing 24
chr14_+_65411845 0.81 ENST00000556518.5
ENST00000557164.5
fucosyltransferase 8
chr1_+_209938169 0.81 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
synaptotagmin 14
chrX_-_16869840 0.80 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr8_-_64798725 0.80 ENST00000310193.4
cytochrome P450 family 7 subfamily B member 1
chr9_-_136304084 0.79 ENST00000638797.2
ENST00000624277.3
coiled-coil domain containing 187
chr8_-_141002072 0.77 ENST00000517453.5
protein tyrosine kinase 2
chr11_+_933553 0.74 ENST00000534485.5
adaptor related protein complex 2 subunit alpha 2
chr20_+_37383648 0.72 ENST00000373567.6
SRC proto-oncogene, non-receptor tyrosine kinase
chr3_+_138434609 0.71 ENST00000389567.9
ENST00000289135.4
extended synaptotagmin 3
chr14_-_67359821 0.70 ENST00000553687.1
ATPase H+ transporting V1 subunit D
chr6_-_43528867 0.68 ENST00000455285.2
exportin 5
chr21_+_46001300 0.67 ENST00000612273.2
ENST00000682634.1
collagen type VI alpha 1 chain
chr12_-_99984629 0.66 ENST00000683438.1
ENST00000549866.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_126101506 0.66 ENST00000509064.5
ENST00000508835.5
solute carrier family 41 member 3
chr10_-_69409275 0.65 ENST00000373307.5
tachykinin receptor 2
chr2_-_2326210 0.65 ENST00000647755.1
myelin transcription factor 1 like
chr19_-_12919256 0.65 ENST00000293695.8
synaptonemal complex central element protein 2
chr12_-_84912705 0.64 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr19_-_50476838 0.64 ENST00000600100.6
family with sequence similarity 71 member E1
chr1_-_20717996 0.63 ENST00000400463.8
ENST00000247986.2
kinesin family member 17
chr8_+_6708685 0.63 ENST00000518327.1
1-acylglycerol-3-phosphate O-acyltransferase 5
chr11_-_68751441 0.63 ENST00000544963.1
ENST00000443940.6
ENST00000255087.10
testis expressed metallothionein like protein
chr17_+_41967783 0.63 ENST00000585452.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_-_133336169 0.61 ENST00000372022.6
surfeit 6
chr14_+_85533167 0.60 ENST00000682132.1
fibronectin leucine rich transmembrane protein 2
chr22_-_50085378 0.60 ENST00000442311.1
modulator of VRAC current 1
chrX_-_16870325 0.60 ENST00000468092.1
ENST00000404022.5
ENST00000380087.7
RB binding protein 7, chromatin remodeling factor
chr2_-_231464156 0.60 ENST00000453992.6
ENST00000454824.6
ENST00000417652.6
nucleolin
chr20_-_43726989 0.59 ENST00000373003.2
gametocyte specific factor 1 like
chr5_+_79236092 0.58 ENST00000396137.5
junction mediating and regulatory protein, p53 cofactor
chr17_-_46979240 0.58 ENST00000322329.5
reprimo like
chr6_+_46652968 0.58 ENST00000371347.10
solute carrier family 25 member 27
chr3_+_48989876 0.57 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr15_-_23039560 0.56 ENST00000615383.5
ENST00000620435.4
tubulin gamma complex associated protein 5
chr4_-_144019287 0.56 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr11_+_46311149 0.56 ENST00000530518.1
cAMP responsive element binding protein 3 like 1
chr15_+_58771280 0.56 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr15_+_90954870 0.55 ENST00000394258.6
ENST00000555155.5
RCC1 domain containing 1
chr11_-_26572102 0.55 ENST00000455601.6
mucin 15, cell surface associated
chr19_+_12995467 0.54 ENST00000592199.6
nuclear factor I X
chr11_-_795286 0.53 ENST00000627843.2
ENST00000527723.5
ENST00000526152.5
ENST00000456706.6
ENST00000625419.2
solute carrier family 25 member 22
chr14_+_65411932 0.51 ENST00000555559.5
fucosyltransferase 8
chr2_+_64989343 0.49 ENST00000234256.4
solute carrier family 1 member 4
chr3_-_24495532 0.49 ENST00000643772.1
ENST00000642307.1
ENST00000645139.1
thyroid hormone receptor beta
chr15_-_42920638 0.48 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
tau tubulin kinase 2
chr10_+_48306639 0.48 ENST00000395611.7
ENST00000432379.5
ENST00000374189.5
mitogen-activated protein kinase 8
chr6_+_98834560 0.48 ENST00000328345.8
POU class 3 homeobox 2
chr6_+_46652914 0.47 ENST00000411689.6
solute carrier family 25 member 27
chr19_-_45642440 0.47 ENST00000588172.1
EMAP like 2
chr11_-_46846233 0.46 ENST00000529230.6
ENST00000312055.9
cytoskeleton associated protein 5
chr21_-_32612806 0.46 ENST00000673807.1
CFAP298-TCP10L readthrough
chr14_+_58395912 0.46 ENST00000360945.7
translocase of outer mitochondrial membrane 20 like
chr2_-_2326378 0.45 ENST00000647618.1
myelin transcription factor 1 like
chr17_-_7916280 0.45 ENST00000324348.9
ring finger protein 227
chr8_+_103021027 0.45 ENST00000518857.5
ENST00000395862.7
ENST00000518738.2
ENST00000521514.5
ATPase H+ transporting V1 subunit C1
chr11_+_60429595 0.45 ENST00000528905.1
ENST00000528093.1
membrane spanning 4-domains A5
chr19_+_49388243 0.45 ENST00000447857.8
KASH domain containing 5
chr1_+_43991588 0.44 ENST00000372318.8
coiled-coil domain containing 24
chr16_+_8882347 0.43 ENST00000637237.1
LITAF domain containing
chr9_+_12693327 0.42 ENST00000388918.10
tyrosinase related protein 1
chr19_-_1997406 0.42 ENST00000587825.1
BTB domain containing 2
chr21_+_44353633 0.42 ENST00000397932.6
ENST00000300481.13
transient receptor potential cation channel subfamily M member 2
chrX_+_154295788 0.42 ENST00000369915.8
transketolase like 1
chr11_-_69675367 0.42 ENST00000542341.1
LTO1 maturation factor of ABCE1
chr17_-_44830242 0.41 ENST00000592524.6
gap junction protein gamma 1
chr7_-_1459461 0.37 ENST00000297508.8
MICAL like 2
chr19_+_42306937 0.37 ENST00000595750.2
proline rich 19
chr16_+_83968244 0.35 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr5_+_179699003 0.34 ENST00000681733.1
ENST00000680006.1
ENST00000680013.1
ENST00000681076.1
ENST00000681168.1
calnexin
chr16_+_3500964 0.34 ENST00000574369.5
ENST00000576634.6
ENST00000341633.9
ENST00000571025.5
clusterin associated protein 1
chr19_+_57584131 0.33 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
zinc finger protein interacting with K protein 1
chr17_+_47971136 0.31 ENST00000583352.5
CDK5 regulatory subunit associated protein 3
chr10_+_48306698 0.31 ENST00000374179.8
mitogen-activated protein kinase 8
chr19_+_37346283 0.31 ENST00000541583.6
zinc finger protein 875
chr2_+_200305873 0.31 ENST00000439084.5
ENST00000409718.5
spermatogenesis associated serine rich 2 like
chr19_+_840991 0.31 ENST00000234347.10
proteinase 3
chr19_-_52008081 0.30 ENST00000602063.5
ENST00000597747.5
ENST00000594083.5
ENST00000593650.5
ENST00000599631.5
ENST00000598071.6
ENST00000601178.5
ENST00000376716.9
ENST00000391795.7
zinc finger protein 615
chr8_+_6708626 0.30 ENST00000285518.11
1-acylglycerol-3-phosphate O-acyltransferase 5
chr7_-_6272639 0.29 ENST00000396741.3
cytohesin 3
chr20_-_45910898 0.29 ENST00000372420.5
phospholipid transfer protein
chr10_-_131982006 0.29 ENST00000368636.8
BCL2 interacting protein 3
chr3_-_151384741 0.28 ENST00000302632.4
purinergic receptor P2Y12
chr4_+_183506082 0.28 ENST00000412117.1
inhibitor of growth family member 2
chr12_-_6647393 0.27 ENST00000536350.5
ENST00000414226.6
ENST00000229243.7
ENST00000546114.1
acrosin binding protein
chr8_-_29263087 0.27 ENST00000521515.1
kinesin family member 13B
chr10_+_16436996 0.27 ENST00000535784.7
phosphotriesterase related
chr17_+_59685117 0.26 ENST00000475458.1
clathrin heavy chain
chr22_+_30356974 0.26 ENST00000445005.5
ENST00000430839.5
ENST00000338306.8
coiled-coil domain containing 157
chr6_-_113971120 0.26 ENST00000520895.5
ENST00000521163.5
ENST00000524334.1
ENST00000519065.6
ENST00000368632.6
histone deacetylase 2
chr11_+_62761570 0.26 ENST00000301788.12
RNA polymerase II subunit G
chr19_-_9936501 0.25 ENST00000264833.9
olfactomedin 2
chr16_-_81096163 0.25 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr10_+_4786624 0.25 ENST00000533295.5
aldo-keto reductase family 1 member E2
chr10_+_116324440 0.24 ENST00000333254.4
coiled-coil domain containing 172
chr12_+_27022543 0.24 ENST00000546323.5
ENST00000282892.4
mediator complex subunit 21
chr11_-_26572130 0.24 ENST00000527569.1
mucin 15, cell surface associated
chr16_+_75222609 0.24 ENST00000495583.1
chymotrypsinogen B1
chr3_+_126394890 0.24 ENST00000352312.6
cilia and flagella associated protein 100
chr9_+_127451495 0.24 ENST00000373324.8
ENST00000675572.1
ENST00000676170.1
ENST00000675789.1
ENST00000300417.11
ENST00000675448.1
ENST00000323301.8
ENST00000675141.1
leucine rich repeat and sterile alpha motif containing 1
chr17_-_7211808 0.23 ENST00000648658.1
discs large MAGUK scaffold protein 4
chr9_-_21240002 0.23 ENST00000380222.4
interferon alpha 14
chr17_-_7915929 0.23 ENST00000635932.1
ENST00000640240.1
ring finger protein 227
chr2_-_168913277 0.22 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr19_-_1822038 0.21 ENST00000643515.1
RNA exonuclease 1 homolog
chr8_-_29263063 0.21 ENST00000524189.6
kinesin family member 13B
chr5_+_179698906 0.20 ENST00000452673.6
ENST00000680614.1
ENST00000680812.1
ENST00000681265.1
ENST00000680894.1
ENST00000681894.1
ENST00000679642.1
ENST00000680827.1
ENST00000680984.1
ENST00000680042.1
ENST00000681476.1
ENST00000681072.1
ENST00000247461.9
ENST00000502673.6
ENST00000513246.6
ENST00000680618.1
ENST00000680092.1
ENST00000506654.6
calnexin
chr2_-_85888897 0.20 ENST00000639305.1
ENST00000638986.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr19_+_571274 0.20 ENST00000545507.6
ENST00000346916.9
basigin (Ok blood group)
chr2_-_85888958 0.20 ENST00000377332.8
ENST00000639119.1
ENST00000638572.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr14_+_77181623 0.20 ENST00000554766.5
transmembrane protein 63C
chr17_+_47971105 0.19 ENST00000338399.9
ENST00000578018.5
ENST00000579175.5
CDK5 regulatory subunit associated protein 3
chr20_-_47356670 0.19 ENST00000540497.5
ENST00000461685.5
ENST00000617418.4
ENST00000435836.5
ENST00000471951.6
ENST00000352431.6
ENST00000360911.7
ENST00000458360.6
zinc finger MYND-type containing 8
chr20_-_18413216 0.19 ENST00000480488.2
double zinc ribbon and ankyrin repeat domains 1
chr7_+_876545 0.18 ENST00000265857.8
guided entry of tail-anchored proteins factor 4
chr12_-_123243998 0.18 ENST00000545406.1
M-phase phosphoprotein 9
chr20_-_47356721 0.18 ENST00000262975.8
ENST00000446994.6
ENST00000355972.8
ENST00000396281.8
ENST00000619049.4
ENST00000611941.4
ENST00000372023.7
zinc finger MYND-type containing 8
chr15_+_43826961 0.17 ENST00000381246.6
ENST00000452115.1
ENST00000263795.11
WD repeat domain 76
chr13_-_41194485 0.17 ENST00000379483.4
kelch repeat and BTB domain containing 7
chr4_+_183659267 0.17 ENST00000357207.8
ENST00000334690.11
trafficking protein particle complex 11
chr18_-_46757012 0.16 ENST00000315087.12
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr21_+_44012296 0.16 ENST00000291574.9
ENST00000380221.7
trafficking protein particle complex 10
chr20_+_5750381 0.16 ENST00000378979.8
ENST00000303142.11
shieldin complex subunit 1
chr2_-_85888685 0.16 ENST00000638178.1
ENST00000640982.1
ENST00000640992.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_122896066 0.15 ENST00000267202.7
ENST00000535765.5
VPS37B subunit of ESCRT-I
chr14_-_81220951 0.15 ENST00000553612.6
general transcription factor IIA subunit 1
chr7_-_102579796 0.15 ENST00000538869.2
RAS p21 protein activator 4
chrX_+_10158448 0.15 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr21_+_41322805 0.15 ENST00000398646.3
FAM3 metabolism regulating signaling molecule B
chr8_+_143291384 0.15 ENST00000521537.1
ENST00000518432.5
ENST00000330143.8
ENST00000520333.1
zinc finger protein 696

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 32.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.6 6.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.5 1.4 GO:0021529 noradrenergic neuron development(GO:0003358) neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 1.4 GO:0007309 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.4 4.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 3.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.4 3.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 5.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 0.8 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 1.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.3 1.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 0.8 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.7 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 1.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.2 1.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 1.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.2 0.6 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.9 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 2.0 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.7 GO:0035106 operant conditioning(GO:0035106)
0.1 2.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 3.4 GO:0015671 oxygen transport(GO:0015671)
0.1 1.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.5 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.6 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.4 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.3 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:1903756 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0071569 protein ufmylation(GO:0071569)
0.0 2.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.5 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:1904139 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 2.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 3.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.9 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 3.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.0 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0044308 axonal spine(GO:0044308)
0.5 1.5 GO:0030849 autosome(GO:0030849)
0.4 3.5 GO:0032279 asymmetric synapse(GO:0032279)
0.2 0.7 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 2.9 GO:0033391 chromatoid body(GO:0033391)
0.2 1.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 0.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 3.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0000801 central element(GO:0000801)
0.1 3.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.6 GO:0001652 granular component(GO:0001652)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.6 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 3.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.2 GO:0097545 axonemal outer doublet(GO:0097545)
0.1 5.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.3 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 6.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 35.3 GO:0005874 microtubule(GO:0005874)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 3.7 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 2.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.7 3.4 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.6 1.7 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.5 4.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 1.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 3.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3 1.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 0.7 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 0.7 GO:0016497 substance K receptor activity(GO:0016497)
0.2 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 5.5 GO:0031005 filamin binding(GO:0031005)
0.2 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 0.5 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 3.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 1.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.6 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.6 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 3.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 34.9 GO:0015631 tubulin binding(GO:0015631)
0.0 3.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.0 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 2.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 2.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 32.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 5.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 4.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 3.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 6.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 4.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport