ISMARA results: HESX1

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avrg: Illumina Body Map 2 (GSE30611)

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Results for HESX1

Z-value: 2.20

Motif logo

Transcription factors associated with HESX1

Gene Symbol	Gene ID	Gene Info
HESX1 Ensembl NCBI GeneCards UniProt	ENSG00000163666.10	HESX1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HESX1	hg38_v1_chr3_-_57226344_57226521	-0.34	5.9e-02	Click!

Activity profile of HESX1 motif

Sorted Z-values of HESX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr2_-_89117844 Show fit	10.81	ENST00000490686.1	IGKV1-17 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-17
chr14_-_105940235 Show fit	10.57	ENST00000390593.2	IGHV6-1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 6-1
chr2_+_89862438 Show fit	9.83	ENST00000448155.2	IGKV1D-39 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-39
chr2_-_88947820 Show fit	9.80	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr2_+_89913982 Show fit	9.70	ENST00000390265.2	IGKV1D-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-33
chr2_-_89268506 Show fit	9.35	ENST00000473726.1	IGKV1-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-33
chr2_-_89100352 Show fit	8.84	ENST00000479981.1	IGKV1-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr2_+_90159840 Show fit	7.97	ENST00000377032.5	IGKV1D-12 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr2_-_89010515 Show fit	7.20	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr2_-_89213917 Show fit	7.16	ENST00000498435.1	IGKV1-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-27
chr14_-_106012390 Show fit	6.47	ENST00000455737.2	IGHV4-4 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 4-4
chr2_+_90154073 Show fit	6.18	ENST00000611391.1	IGKV1D-13 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr2_-_88966767 Show fit	5.69	ENST00000464162.1	IGKV1-6 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-6
chr2_+_90220727 Show fit	5.10	ENST00000471857.2	IGKV1D-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-8
chrX_+_48676596 Show fit	4.67	ENST00000450772.5	WAS Ensembl NCBI GeneCards UniProt Show fit	WASP actin nucleation promoting factor
chr11_-_118342691 Show fit	4.52	ENST00000300692.9	CD3D Ensembl NCBI GeneCards UniProt Show fit	CD3d molecule
chrX_+_136648138 Show fit	4.19	ENST00000370629.7	CD40LG Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr2_-_88992903 Show fit	4.18	ENST00000495489.1	IGKV1-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr5_+_40679907 Show fit	4.14	ENST00000302472.4	PTGER4 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 4
chr17_-_82317523 Show fit	4.11	ENST00000583376.1 ENST00000578509.1 ENST00000584284.5 ENST00000582480.1	CD7 Ensembl NCBI GeneCards UniProt Show fit	CD7 molecule
chr2_+_113406368 Show fit	4.03	ENST00000453673.3	IGKV1OR2-108 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1/OR2-108 (non-functional)
chrX_+_136648214 Show fit	3.67	ENST00000370628.2	CD40LG Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr14_-_105601728 Show fit	3.37	ENST00000641420.1 ENST00000390541.2	IGHE Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant epsilon
chr2_+_89884740 Show fit	3.32	ENST00000509129.1	IGKV1D-37 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-37 (non-functional)
chr11_+_67455352 Show fit	3.03	ENST00000325656.7	CABP4 Ensembl NCBI GeneCards UniProt Show fit	calcium binding protein 4
chr2_+_90209873 Show fit	2.99	ENST00000468879.1	IGKV1D-43 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-43
chr2_-_89297785 Show fit	2.84	ENST00000465170.1	IGKV1-37 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-37 (non-functional)
chr19_-_45076465 Show fit	2.63	ENST00000303809.7	ZNF296 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 296
chr1_-_205321737 Show fit	2.60	ENST00000367157.6	NUAK2 Ensembl NCBI GeneCards UniProt Show fit	NUAK family kinase 2
chr14_-_91836440 Show fit	2.21	ENST00000340892.9 ENST00000360594.9	TC2N Ensembl NCBI GeneCards UniProt Show fit	tandem C2 domains, nuclear
chr19_-_45076504 Show fit	2.15	ENST00000622376.1	ZNF296 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 296
chr14_+_61187544 Show fit	2.13	ENST00000555185.5 ENST00000557294.5 ENST00000556778.5	PRKCH Ensembl NCBI GeneCards UniProt Show fit	protein kinase C eta
chr14_-_24634160 Show fit	2.12	ENST00000616551.1 ENST00000382542.5 ENST00000216341.9 ENST00000526004.1 ENST00000415355.7	GZMB Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr4_+_153684241 Show fit	2.11	ENST00000646219.1 ENST00000642580.1 ENST00000643501.1 ENST00000642700.2	TLR2 Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 2
chr1_+_44800367 Show fit	1.96	ENST00000372201.5	PLK3 Ensembl NCBI GeneCards UniProt Show fit	polo like kinase 3
chr14_+_22304051 Show fit	1.93	ENST00000390466.1	TRAV39 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 39
chr6_-_41736239 Show fit	1.89	ENST00000358871.6	TFEB Ensembl NCBI GeneCards UniProt Show fit	transcription factor EB
chr14_-_91836526 Show fit	1.86	ENST00000556018.5	TC2N Ensembl NCBI GeneCards UniProt Show fit	tandem C2 domains, nuclear
chr17_-_63931354 Show fit	1.76	ENST00000647774.1	ENSG00000285947.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr16_+_56961917 Show fit	1.74	ENST00000379780.6	CETP Ensembl NCBI GeneCards UniProt Show fit	cholesteryl ester transfer protein
chr1_-_20119527 Show fit	1.72	ENST00000375105.8 ENST00000617227.1	PLA2G2D Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IID
chr22_+_24424372 Show fit	1.71	ENST00000464977.5 ENST00000444262.6	ADORA2A Ensembl NCBI GeneCards UniProt Show fit	adenosine A2a receptor
chr17_+_63998344 Show fit	1.65	ENST00000577953.5 ENST00000582540.5 ENST00000579184.5 ENST00000425164.7 ENST00000412177.6 ENST00000583891.5 ENST00000580752.1	PRR29 Ensembl NCBI GeneCards UniProt Show fit	proline rich 29
chr6_-_46735351 Show fit	1.64	ENST00000274793.12	PLA2G7 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group VII
chr14_+_21846534 Show fit	1.59	ENST00000390434.3	TRAV8-2 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 8-2
chr19_-_18086904 Show fit	1.52	ENST00000322153.11 ENST00000593993.7	IL12RB1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 12 receptor subunit beta 1
chr19_-_19628512 Show fit	1.46	ENST00000588461.1	LPAR2 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 2
chr8_+_123072667 Show fit	1.44	ENST00000519418.5 ENST00000287380.6 ENST00000327098.9 ENST00000522420.5 ENST00000521676.5	TBC1D31 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 31
chr8_+_141391989 Show fit	1.38	ENST00000520105.5 ENST00000523147.5 ENST00000521578.6	PTP4A3 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase 4A3
chr2_+_240605417 Show fit	1.29	ENST00000319838.10 ENST00000403859.1	GPR35 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 35
chr18_-_12883766 Show fit	1.28	ENST00000645191.1 ENST00000646492.1	PTPN2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 2
chr7_-_47581631 Show fit	1.27	ENST00000434451.1	TNS3 Ensembl NCBI GeneCards UniProt Show fit	tensin 3
chr19_-_19628197 Show fit	1.22	ENST00000586703.1 ENST00000591042.1 ENST00000407877.8	LPAR2 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 2
chr17_+_30921935 Show fit	1.20	ENST00000581285.5 ENST00000330889.8	ADAP2 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with dual PH domains 2
chr20_-_63956382 Show fit	1.18	ENST00000358711.7 ENST00000354216.11	UCKL1 Ensembl NCBI GeneCards UniProt Show fit	uridine-cytidine kinase 1 like 1
chr14_-_24195334 Show fit	1.17	ENST00000530563.1 ENST00000528895.5 ENST00000528669.5 ENST00000532632.1 ENST00000261789.9	TM9SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 1
chr2_+_219206768 Show fit	1.14	ENST00000289528.10 ENST00000409206.5 ENST00000444522.6 ENST00000621130.4 ENST00000409594.5 ENST00000422255.5 ENST00000409412.5 ENST00000409097.5 ENST00000409336.5 ENST00000409217.5	ZFAND2B Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 2B
chr9_-_128724088 Show fit	1.14	ENST00000406904.2 ENST00000452105.5 ENST00000372667.9 ENST00000372663.9	ZDHHC12 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 12
chr14_-_24634266 Show fit	1.14	ENST00000382540.5	GZMB Ensembl NCBI GeneCards UniProt Show fit	granzyme B
chr2_+_219206875 Show fit	1.10	ENST00000409319.5	ZFAND2B Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 2B
chr19_+_37907200 Show fit	1.09	ENST00000222345.11	SIPA1L3 Ensembl NCBI GeneCards UniProt Show fit	signal induced proliferation associated 1 like 3
chr12_-_46268989 Show fit	1.08	ENST00000549049.5 ENST00000439706.5 ENST00000398637.10	SLC38A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 1
chr19_-_49867542 Show fit	1.05	ENST00000600910.5 ENST00000322344.8 ENST00000600573.5 ENST00000596726.3 ENST00000638016.1	PNKP Ensembl NCBI GeneCards UniProt Show fit	polynucleotide kinase 3'-phosphatase
chr10_-_43408787 Show fit	1.02	ENST00000356053.7	HNRNPF Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr17_+_75093287 Show fit	1.01	ENST00000538213.6 ENST00000584118.1	SLC16A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 5
chr4_-_143905529 Show fit	1.01	ENST00000358615.9 ENST00000437468.2	GYPE Ensembl NCBI GeneCards UniProt Show fit	glycophorin E (MNS blood group)
chr17_+_47209035 Show fit	0.96	ENST00000572316.5 ENST00000354968.5 ENST00000576874.5 ENST00000536623.6	MYL4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr7_+_142407663 Show fit	0.95	ENST00000390367.3	TRBV11-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 11-1
chr15_+_66453418 Show fit	0.95	ENST00000566326.1	MAP2K1 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 1
chr11_-_126268810 Show fit	0.93	ENST00000332118.11	SRPRA Ensembl NCBI GeneCards UniProt Show fit	SRP receptor subunit alpha
chrX_+_153972729 Show fit	0.92	ENST00000369982.5	TMEM187 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 187
chr14_+_45084093 Show fit	0.92	ENST00000553605.1 ENST00000355765.11	PRPF39 Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 39
chr7_+_100148890 Show fit	0.91	ENST00000341942.9 ENST00000474141.5 ENST00000460732.5 ENST00000441173.1 ENST00000468582.5 ENST00000488241.5	LAMTOR4 Ensembl NCBI GeneCards UniProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr12_-_56630293 Show fit	0.89	ENST00000546695.5 ENST00000549884.6	BAZ2A Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 2A
chr19_-_49867251 Show fit	0.88	ENST00000631020.2 ENST00000596014.5 ENST00000636994.1	PNKP Ensembl NCBI GeneCards UniProt Show fit	polynucleotide kinase 3'-phosphatase
chr11_-_4393650 Show fit	0.88	ENST00000254436.8	TRIM21 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 21
chr2_-_43595963 Show fit	0.87	ENST00000405006.8	THADA Ensembl NCBI GeneCards UniProt Show fit	THADA armadillo repeat containing
chr3_-_46693641 Show fit	0.86	ENST00000415953.5	ALS2CL Ensembl NCBI GeneCards UniProt Show fit	ALS2 C-terminal like
chr14_-_100376251 Show fit	0.86	ENST00000556645.5 ENST00000556209.5 ENST00000556504.5 ENST00000556435.5 ENST00000554772.5 ENST00000553581.1 ENST00000553769.6 ENST00000554605.5 ENST00000557722.5 ENST00000553413.5 ENST00000553524.5 ENST00000358655.8	WARS1 Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr17_+_49495286 Show fit	0.86	ENST00000172229.8	NGFR Ensembl NCBI GeneCards UniProt Show fit	nerve growth factor receptor
chr2_-_43595980 Show fit	0.85	ENST00000403856.1 ENST00000404790.5 ENST00000405975.7	THADA Ensembl NCBI GeneCards UniProt Show fit	THADA armadillo repeat containing
chr12_-_54973547 Show fit	0.80	ENST00000526532.5 ENST00000532757.5	TESPA1 Ensembl NCBI GeneCards UniProt Show fit	thymocyte expressed, positive selection associated 1
chr12_+_103930600 Show fit	0.77	ENST00000680316.1 ENST00000679861.1	HSP90B1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein 90 beta family member 1
chr14_+_20469399 Show fit	0.75	ENST00000361505.10 ENST00000553591.1	PNP Ensembl NCBI GeneCards UniProt Show fit	purine nucleoside phosphorylase
chr20_+_37179310 Show fit	0.75	ENST00000373632.8 ENST00000237530.11	RPN2 Ensembl NCBI GeneCards UniProt Show fit	ribophorin II
chr1_-_52553387 Show fit	0.71	ENST00000484723.6 ENST00000524582.1	TUT4 Ensembl NCBI GeneCards UniProt Show fit	terminal uridylyl transferase 4
chr2_-_96265942 Show fit	0.69	ENST00000432959.1 ENST00000258439.8	TMEM127 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 127
chr11_+_18394586 Show fit	0.68	ENST00000227157.8 ENST00000478970.6 ENST00000495052.5	LDHA Ensembl NCBI GeneCards UniProt Show fit	lactate dehydrogenase A
chr5_-_88883701 Show fit	0.65	ENST00000636998.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr1_+_45550783 Show fit	0.64	ENST00000621846.4 ENST00000434299.5 ENST00000351829.9	AKR1A1 Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member A1
chr1_-_26046111 Show fit	0.63	ENST00000374278.7 ENST00000374276.4	SLC30A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 member 2
chr3_+_133574434 Show fit	0.63	ENST00000508481.5 ENST00000420115.6 ENST00000504867.5 ENST00000507408.5 ENST00000511392.5 ENST00000515421.1	CDV3 Ensembl NCBI GeneCards UniProt Show fit	CDV3 homolog
chr20_+_37179109 Show fit	0.62	ENST00000373622.9	RPN2 Ensembl NCBI GeneCards UniProt Show fit	ribophorin II
chr10_-_14548646 Show fit	0.62	ENST00000378470.5	FAM107B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member B
chr3_+_16265160 Show fit	0.59	ENST00000627468.2 ENST00000605932.5 ENST00000435829.6 ENST00000285083.10	OXNAD1 Ensembl NCBI GeneCards UniProt Show fit	oxidoreductase NAD binding domain containing 1
chr12_-_120581361 Show fit	0.59	ENST00000341039.6 ENST00000357500.5	POP5 Ensembl NCBI GeneCards UniProt Show fit	POP5 homolog, ribonuclease P/MRP subunit
chr8_+_96261891 Show fit	0.59	ENST00000517309.6	PTDSS1 Ensembl NCBI GeneCards UniProt Show fit	phosphatidylserine synthase 1
chr11_+_65181920 Show fit	0.58	ENST00000279247.11 ENST00000532285.1 ENST00000534373.5	CAPN1 Ensembl NCBI GeneCards UniProt Show fit	calpain 1
chr2_-_85602681 Show fit	0.57	ENST00000334462.10 ENST00000306353.7	TMEM150A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 150A
chr12_-_46269105 Show fit	0.57	ENST00000546893.5	SLC38A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 1
chr2_-_85602351 Show fit	0.56	ENST00000409668.1	TMEM150A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 150A
chr16_-_84240012 Show fit	0.55	ENST00000308251.6	KCNG4 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel modifier subfamily G member 4
chr2_-_1744442 Show fit	0.54	ENST00000433670.5 ENST00000425171.1 ENST00000252804.9	PXDN Ensembl NCBI GeneCards UniProt Show fit	peroxidasin
chr16_+_21597204 Show fit	0.52	ENST00000567404.5	METTL9 Ensembl NCBI GeneCards UniProt Show fit	methyltransferase like 9
chr2_-_37672448 Show fit	0.52	ENST00000611976.1	CDC42EP3 Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein 3
chr8_+_145052447 Show fit	0.49	ENST00000331434.7 ENST00000648531.1 ENST00000647640.1 ENST00000647724.1 ENST00000648784.1	C8orf33 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 33
chr7_-_36985060 Show fit	0.49	ENST00000396040.6	ELMO1 Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 1
chr7_-_2555477 Show fit	0.48	ENST00000340611.9	BRAT1 Ensembl NCBI GeneCards UniProt Show fit	BRCA1 associated ATM activator 1
chr11_+_102347205 Show fit	0.47	ENST00000532832.5 ENST00000530675.5 ENST00000227758.7 ENST00000533742.5 ENST00000532672.5 ENST00000531259.5 ENST00000527465.1	BIRC2 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 2
chr17_-_38853629 Show fit	0.47	ENST00000378096.3 ENST00000479035.7 ENST00000394332.5 ENST00000394333.5 ENST00000577407.5	RPL23 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L23
chr16_-_84239750 Show fit	0.46	ENST00000568181.1	KCNG4 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel modifier subfamily G member 4
chr12_-_53676314 Show fit	0.45	ENST00000549164.5	ATP5MC2 Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 2
chr17_+_19378476 Show fit	0.44	ENST00000395604.8 ENST00000482850.1	MAPK7 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 7
chr11_-_126268913 Show fit	0.44	ENST00000532259.1	SRPRA Ensembl NCBI GeneCards UniProt Show fit	SRP receptor subunit alpha
chr1_+_45551031 Show fit	0.44	ENST00000481885.5 ENST00000471651.1	AKR1A1 Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member A1
chr12_-_643620 Show fit	0.43	ENST00000433832.2 ENST00000542920.1	NINJ2 Ensembl NCBI GeneCards UniProt Show fit	ninjurin 2
chr9_+_129835442 Show fit	0.43	ENST00000372429.8 ENST00000315480.9 ENST00000358355.5	USP20 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 20
chr12_-_113471851 Show fit	0.43	ENST00000261731.4	LHX5 Ensembl NCBI GeneCards UniProt Show fit	LIM homeobox 5
chr4_+_159282498 Show fit	0.42	ENST00000514565.1	RAPGEF2 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 2
chr9_-_127847117 Show fit	0.42	ENST00000480266.5	ENG Ensembl NCBI GeneCards UniProt Show fit	endoglin
chr6_-_41921105 Show fit	0.42	ENST00000434077.1 ENST00000409312.5 ENST00000265350.9	MED20 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 20
chrX_+_153972769 Show fit	0.42	ENST00000425274.1	TMEM187 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 187
chr11_-_66438788 Show fit	0.42	ENST00000329819.4 ENST00000310999.11 ENST00000430466.6	MRPL11 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L11
chr7_+_101815904 Show fit	0.41	ENST00000437600.9 ENST00000645010.1 ENST00000646649.1	CUX1 Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 1
chr12_+_123233420 Show fit	0.41	ENST00000253233.6 ENST00000366329.7 ENST00000546132.2 ENST00000536130.2	C12orf65 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 65
chr3_+_130929998 Show fit	0.40	ENST00000508297.2	ATP2C1 Ensembl NCBI GeneCards UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr12_-_53676720 Show fit	0.38	ENST00000673498.1	ATP5MC2 Ensembl NCBI GeneCards UniProt Show fit	ATP synthase membrane subunit c locus 2
chr1_-_1232061 Show fit	0.37	ENST00000660930.1	SDF4 Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr3_-_196968864 Show fit	0.36	ENST00000443835.1	PIGZ Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class Z
chr1_-_1232031 Show fit	0.35	ENST00000263741.12	SDF4 Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr10_-_45594491 Show fit	0.35	ENST00000453980.3	MARCHF8 Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 8
chr1_-_1231966 Show fit	0.35	ENST00000360001.12	SDF4 Ensembl NCBI GeneCards UniProt Show fit	stromal cell derived factor 4
chr7_-_113118544 Show fit	0.33	ENST00000397764.8 ENST00000441359.1	SMIM30 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 30
chr19_+_11346556 Show fit	0.33	ENST00000587531.5	CCDC159 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 159
chr6_-_144008118 Show fit	0.33	ENST00000629195.2 ENST00000650125.1 ENST00000647880.1 ENST00000649307.1 ENST00000674357.1 ENST00000417959.4 ENST00000635591.1	PLAGL1 Ensembl NCBI GeneCards UniProt Show fit HYMAI Ensembl NCBI GeneCards UniProt Show fit	PLAG1 like zinc finger 1 hydatidiform mole associated and imprinted
chr1_+_1232214 Show fit	0.33	ENST00000379198.5	B3GALT6 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-galactosyltransferase 6
chr14_-_70416973 Show fit	0.33	ENST00000555276.5 ENST00000617124.4	COX16 Ensembl NCBI GeneCards UniProt Show fit SYNJ2BP-COX16 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase assembly factor COX16 SYNJ2BP-COX16 readthrough
chr2_-_70717736 Show fit	0.32	ENST00000415348.5	ADD2 Ensembl NCBI GeneCards UniProt Show fit	adducin 2
chr6_+_31971831 Show fit	0.32	ENST00000375331.7 ENST00000375333.3	STK19 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 19
chr6_+_131573219 Show fit	0.31	ENST00000356962.2 ENST00000368087.8 ENST00000673427.1 ENST00000640973.1	ARG1 Ensembl NCBI GeneCards UniProt Show fit	arginase 1
chr15_+_80072559 Show fit	0.31	ENST00000560228.5 ENST00000559835.5 ENST00000559775.5 ENST00000558688.5 ENST00000560392.5 ENST00000560976.5 ENST00000558272.5 ENST00000558390.5	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr19_+_19320817 Show fit	0.31	ENST00000262815.13 ENST00000609122.5	MAU2 Ensembl NCBI GeneCards UniProt Show fit	MAU2 sister chromatid cohesion factor
chr2_+_134254065 Show fit	0.30	ENST00000281923.4	MGAT5 Ensembl NCBI GeneCards UniProt Show fit	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr10_-_45594760 Show fit	0.30	ENST00000319836.7	MARCHF8 Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 8
chr9_-_37904085 Show fit	0.30	ENST00000377716.6 ENST00000242275.7	SLC25A51 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 51
chr6_-_41921081 Show fit	0.29	ENST00000409060.1	MED20 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 20
chr4_+_8580387 Show fit	0.29	ENST00000382487.5	GPR78 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 78
chr10_-_99620401 Show fit	0.28	ENST00000370495.6	SLC25A28 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 28
chr6_-_31170620 Show fit	0.28	ENST00000638788.1 ENST00000259915.13	POU5F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 5 homeobox 1
chr11_-_57381146 Show fit	0.27	ENST00000287143.2	PRG3 Ensembl NCBI GeneCards UniProt Show fit	proteoglycan 3, pro eosinophil major basic protein 2
chr6_+_26272923 Show fit	0.27	ENST00000377733.4	H2BC10 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 10
chr18_+_46917492 Show fit	0.26	ENST00000592005.5	KATNAL2 Ensembl NCBI GeneCards UniProt Show fit	katanin catalytic subunit A1 like 2
chr6_+_85449584 Show fit	0.26	ENST00000369651.7	NT5E Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr4_-_48780242 Show fit	0.25	ENST00000507711.5 ENST00000358350.9	FRYL Ensembl NCBI GeneCards UniProt Show fit	FRY like transcription coactivator
chr19_-_11346196 Show fit	0.24	ENST00000586218.5	TMEM205 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 205
chr6_+_143536811 Show fit	0.24	ENST00000367584.8	PHACTR2 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 2
chr5_+_163437569 Show fit	0.24	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chr8_-_92017637 Show fit	0.24	ENST00000422361.6	RUNX1T1 Ensembl NCBI GeneCards UniProt Show fit	RUNX1 partner transcriptional co-repressor 1
chr17_+_47209375 Show fit	0.23	ENST00000572303.1	MYL4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr19_-_18086989 Show fit	0.23	ENST00000430026.7	IL12RB1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 12 receptor subunit beta 1
chr1_-_15976114 Show fit	0.23	ENST00000375733.6	ZBTB17 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 17
chr10_-_70233420 Show fit	0.22	ENST00000373232.8 ENST00000625364.1	PPA1 Ensembl NCBI GeneCards UniProt Show fit	inorganic pyrophosphatase 1
chr2_-_230925226 Show fit	0.22	ENST00000622008.4 ENST00000392040.5 ENST00000438398.1 ENST00000650999.1	GPR55 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 55
chr17_+_47209338 Show fit	0.22	ENST00000393450.5	MYL4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr1_+_47333863 Show fit	0.22	ENST00000471289.2 ENST00000450808.2	CMPK1 Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 1
chr3_+_178536205 Show fit	0.21	ENST00000420517.6	KCNMB2 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr13_-_51804094 Show fit	0.21	ENST00000280056.6	DHRS12 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 12
chr8_+_78516329 Show fit	0.21	ENST00000396418.7 ENST00000352966.9	PKIA Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor alpha
chr16_-_1420707 Show fit	0.21	ENST00000442039.3	C16orf91 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 91
chr15_+_32030481 Show fit	0.20	ENST00000454250.7 ENST00000675428.1 ENST00000637552.1	CHRNA7 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 7 subunit
chr1_+_47333774 Show fit	0.20	ENST00000371873.10	CMPK1 Ensembl NCBI GeneCards UniProt Show fit	cytidine/uridine monophosphate kinase 1
chr19_-_49866848 Show fit	0.20	ENST00000637897.1	PNKP Ensembl NCBI GeneCards UniProt Show fit	polynucleotide kinase 3'-phosphatase
chr3_-_69013612 Show fit	0.19	ENST00000295571.9	EOGT Ensembl NCBI GeneCards UniProt Show fit	EGF domain specific O-linked N-acetylglucosamine transferase
chr5_-_160119389 Show fit	0.19	ENST00000523662.1 ENST00000456329.7 ENST00000307063.9	PWWP2A Ensembl NCBI GeneCards UniProt Show fit	PWWP domain containing 2A
chr11_-_47565490 Show fit	0.18	ENST00000525841.5 ENST00000530151.5 ENST00000526419.1	CELF1 Ensembl NCBI GeneCards UniProt Show fit	CUGBP Elav-like family member 1
chr10_+_75431605 Show fit	0.18	ENST00000611255.5	LRMDA Ensembl NCBI GeneCards UniProt Show fit	leucine rich melanocyte differentiation associated
chr6_-_83065770 Show fit	0.18	ENST00000369747.8	UBE3D Ensembl NCBI GeneCards UniProt Show fit	ubiquitin protein ligase E3D
chr21_-_33479914 Show fit	0.17	ENST00000542230.7	TMEM50B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 50B
chr1_-_158426237 Show fit	0.17	ENST00000641042.1	OR10K2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily K member 2
chr18_+_24014390 Show fit	0.17	ENST00000584250.1	TTC39C Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 39C
chr16_+_788614 Show fit	0.16	ENST00000262315.14 ENST00000455171.6 ENST00000317063.10	CHTF18 Ensembl NCBI GeneCards UniProt Show fit	chromosome transmission fidelity factor 18
chr12_+_130953898 Show fit	0.16	ENST00000261654.10	ADGRD1 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor D1
chr11_+_102347312 Show fit	0.16	ENST00000621637.1 ENST00000613397.4	BIRC2 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 2
chr15_+_32030506 Show fit	0.16	ENST00000306901.9 ENST00000636440.1	CHRNA7 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 7 subunit
chr3_-_132017749 Show fit	0.16	ENST00000514999.5	CPNE4 Ensembl NCBI GeneCards UniProt Show fit	copine 4
chr12_-_123233164 Show fit	0.15	ENST00000537854.5	MPHOSPH9 Ensembl NCBI GeneCards UniProt Show fit	M-phase phosphoprotein 9
chr5_-_123423337 Show fit	0.15	ENST00000306467.10 ENST00000675330.1 ENST00000674684.1	CEP120 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 120
chr16_+_1612337 Show fit	0.14	ENST00000674071.1 ENST00000397412.8	CRAMP1 Ensembl NCBI GeneCards UniProt Show fit	cramped chromatin regulator homolog 1
chr6_+_116616467 Show fit	0.13	ENST00000229554.10 ENST00000368581.8 ENST00000368580.4	RSPH4A Ensembl NCBI GeneCards UniProt Show fit	radial spoke head component 4A
chr14_-_100375602 Show fit	0.13	ENST00000553395.5 ENST00000553545.5 ENST00000344102.9 ENST00000556338.5 ENST00000553934.1	WARS1 Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr3_-_69013639 Show fit	0.13	ENST00000456376.2 ENST00000383701.8	EOGT Ensembl NCBI GeneCards UniProt Show fit	EGF domain specific O-linked N-acetylglucosamine transferase
chr8_+_6708685 Show fit	0.13	ENST00000518327.1	AGPAT5 Ensembl NCBI GeneCards UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 5
chr3_-_51941874 Show fit	0.13	ENST00000232888.7	RRP9 Ensembl NCBI GeneCards UniProt Show fit	ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr7_+_23597373 Show fit	0.12	ENST00000307471.8 ENST00000409765.5	CCDC126 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 126
chr6_+_85450033 Show fit	0.12	ENST00000257770.8 ENST00000369646.7	NT5E Ensembl NCBI GeneCards UniProt Show fit	5'-nucleotidase ecto
chr18_+_56651385 Show fit	0.12	ENST00000615645.4	WDR7 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 7
chr11_-_72080389 Show fit	0.12	ENST00000351960.10 ENST00000541719.5 ENST00000535111.5	NUMA1 Ensembl NCBI GeneCards UniProt Show fit	nuclear mitotic apparatus protein 1
chr2_+_64453969 Show fit	0.11	ENST00000464281.5	LGALSL Ensembl NCBI GeneCards UniProt Show fit	galectin like
chr17_-_41918966 Show fit	0.10	ENST00000537919.5 ENST00000353196.5 ENST00000393896.6	ACLY Ensembl NCBI GeneCards UniProt Show fit	ATP citrate lyase
chr11_+_71538025 Show fit	0.10	ENST00000398534.4	KRTAP5-8 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.1	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
1.2	4.7	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.7	2.1	GO:0098503	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) DNA 3' dephosphorylation(GO:0098503) DNA 3' dephosphorylation involved in DNA repair(GO:0098504) polynucleotide 3' dephosphorylation(GO:0098506)
0.7	2.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.5	86.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.5	3.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.5	2.0	GO:2000777	endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.4	1.7	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.4	1.3	GO:1902214	regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.4	1.1	GO:0070625	zymogen granule exocytosis(GO:0070625)
0.3	1.7	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.3	7.9	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3	1.7	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.3	4.5	GO:0045059	positive thymic T cell selection(GO:0045059)
0.3	1.6	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.3	0.8	GO:0031247	actin rod assembly(GO:0031247)
0.2	2.2	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2	0.9	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.2	2.1	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2	1.7	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2	41.7	GO:0002377	immunoglobulin production(GO:0002377)
0.2	1.3	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.2	1.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.2	0.6	GO:1902524	positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1	0.4	GO:0070377	negative regulation of ERK5 cascade(GO:0070377)
0.1	1.2	GO:0044211	CTP salvage(GO:0044211)
0.1	0.9	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.4	GO:0001300	chronological cell aging(GO:0001300)
0.1	0.8	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.1	0.9	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.1	0.8	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	1.7	GO:0055091	phospholipid homeostasis(GO:0055091)
0.1	0.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	1.4	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.3	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.1	0.5	GO:0072717	cellular response to actinomycin D(GO:0072717)
0.1	0.7	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.3	GO:0043091	L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1	0.2	GO:0071344	diphosphate metabolic process(GO:0071344)
0.1	0.4	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	4.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	0.3	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.6	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.4	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.9	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	2.5	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.1	0.4	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.4	GO:0006196	AMP catabolic process(GO:0006196)
0.1	0.4	GO:0050893	sensory processing(GO:0050893)
0.0	0.6	GO:0009249	protein lipoylation(GO:0009249)
0.0	4.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.4	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.3	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.4	GO:0072344	rescue of stalled ribosome(GO:0072344)
0.0	0.6	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.6	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.7	GO:0006089	lactate metabolic process(GO:0006089)
0.0	1.7	GO:0001504	neurotransmitter uptake(GO:0001504)
0.0	1.4	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	1.9	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.5	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	1.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.3	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.2	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	1.9	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.5	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	1.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	1.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	1.4	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0	1.6	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.0	0.1	GO:1902846	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0	0.0	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.0	GO:0000964	mitochondrial RNA 5'-end processing(GO:0000964)
0.0	0.4	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0042022	interleukin-12 receptor complex(GO:0042022)
0.5	2.1	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.4	4.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	20.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	48.0	GO:0072562	blood microparticle(GO:0072562)
0.2	1.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.9	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	1.4	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.3	GO:0032116	SMC loading complex(GO:0032116)
0.1	0.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.9	GO:0000243	commitment complex(GO:0000243)
0.1	1.1	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.9	GO:0071986	Ragulator complex(GO:0071986)
0.1	1.6	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.1	1.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.2	GO:0009346	citrate lyase complex(GO:0009346)
0.1	1.1	GO:0032059	bleb(GO:0032059)
0.0	1.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0001534	radial spoke(GO:0001534)
0.0	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	3.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.6	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	1.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	1.7	GO:0048786	axolemma(GO:0030673) presynaptic active zone(GO:0048786)
0.0	0.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	37.9	GO:0005615	extracellular space(GO:0005615)
0.0	3.6	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.5	GO:0043195	terminal bouton(GO:0043195)
0.0	0.8	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0055028	cortical microtubule(GO:0055028)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.9	GO:0005174	CD40 receptor binding(GO:0005174)
0.7	2.1	GO:0046403	polynucleotide 3'-phosphatase activity(GO:0046403)
0.6	1.7	GO:0016517	interleukin-12 receptor activity(GO:0016517)
0.6	1.7	GO:0017129	triglyceride binding(GO:0017129)
0.5	125.2	GO:0003823	antigen binding(GO:0003823)
0.4	4.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.3	1.3	GO:0097677	STAT family protein binding(GO:0097677)
0.3	2.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.2	2.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	1.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	2.3	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.2	0.8	GO:0002060	purine nucleobase binding(GO:0002060)
0.2	1.6	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2	0.5	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.2	1.4	GO:0005047	signal recognition particle binding(GO:0005047)
0.2	0.6	GO:0098770	FBXO family protein binding(GO:0098770)
0.2	1.4	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	1.6	GO:0004849	uridine kinase activity(GO:0004849)
0.1	1.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	4.7	GO:0043274	phospholipase binding(GO:0043274)
0.1	1.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.5	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	1.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.5	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	1.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	1.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.8	GO:0046790	virion binding(GO:0046790)
0.1	0.3	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.4	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.2	GO:0003878	ATP citrate synthase activity(GO:0003878)
0.1	1.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.0	0.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.9	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	1.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	3.0	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	4.1	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.9	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	1.0	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	1.1	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	1.0	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0042835	BRE binding(GO:0042835)
0.0	2.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	5.5	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	3.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	8.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	2.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	2.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	3.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.9	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	4.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	4.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	2.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.9	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	2.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	2.0	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.6	PID PTP1B PATHWAY	Signaling events mediated by PTP1B

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	4.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	4.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.7	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	7.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.9	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	1.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	2.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	3.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	1.7	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	0.9	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	1.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	1.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane

Results for HESX1

Z-value: 2.20

Motif logo

Transcription factors associated with HESX1

Activity-expression correlation:

Activity profile of HESX1 motif

Sorted Z-values of HESX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: