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avrg: Illumina Body Map 2 (GSE30611)

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Results for HMX2

Z-value: 0.84

Motif logo

Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
ENSG00000188816.4 HMX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX2hg38_v1_chr10_+_123148128_1231481450.077.0e-01Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_151025343 2.29 ENST00000521632.1
glutathione peroxidase 3
chr4_-_154590735 1.84 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr10_-_93482194 1.41 ENST00000358334.9
ENST00000371488.3
myoferlin
chr15_+_40764055 1.39 ENST00000260447.6
ENST00000561160.1
ENST00000558670.1
ENST00000559445.1
GTP cyclohydrolase I feedback regulator
chr3_+_155083889 1.37 ENST00000680282.1
membrane metalloendopeptidase
chr3_+_123067016 1.29 ENST00000316218.12
protein disulfide isomerase family A member 5
chr10_-_5003850 1.29 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr2_-_159798234 1.27 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr5_+_157180816 1.27 ENST00000422843.8
IL2 inducible T cell kinase
chr2_-_150487658 1.25 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr17_-_445939 1.23 ENST00000329099.4
refilin B
chr2_-_159798043 1.18 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr2_+_151357583 1.12 ENST00000243347.5
TNF alpha induced protein 6
chr13_-_46168495 1.06 ENST00000416500.5
lymphocyte cytosolic protein 1
chr17_-_31314040 1.04 ENST00000330927.5
ecotropic viral integration site 2B
chr4_+_89901979 1.00 ENST00000508372.1
multimerin 1
chr13_-_48413105 1.00 ENST00000620633.5
lysophosphatidic acid receptor 6
chr1_+_209704836 0.99 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr17_-_66229380 0.98 ENST00000205948.11
apolipoprotein H
chr3_-_187291680 0.98 ENST00000425937.1
ENST00000337774.10
ENST00000296280.11
mannan binding lectin serine peptidase 1
chr8_-_92966129 0.97 ENST00000522925.5
ENST00000522903.5
ENST00000537541.1
ENST00000521988.6
ENST00000518748.5
ENST00000519069.5
triple QxxK/R motif containing
chr6_+_113857333 0.97 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr10_-_93482326 0.93 ENST00000359263.9
myoferlin
chr1_+_186828941 0.92 ENST00000367466.4
phospholipase A2 group IVA
chr6_+_26124161 0.92 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr8_-_92966105 0.88 ENST00000524037.5
ENST00000520430.5
ENST00000521617.5
ENST00000523580.5
triple QxxK/R motif containing
chr7_-_20217342 0.87 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr3_-_149221811 0.86 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr1_-_107688492 0.86 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr8_-_92966081 0.85 ENST00000517858.5
ENST00000378861.9
triple QxxK/R motif containing
chr7_+_26291850 0.85 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr1_-_205321737 0.83 ENST00000367157.6
NUAK family kinase 2
chr12_-_10388976 0.82 ENST00000540818.5
killer cell lectin like receptor K1
chr4_-_99290975 0.82 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr17_-_31314066 0.82 ENST00000577894.1
ecotropic viral integration site 2B
chr2_+_89936859 0.81 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr18_+_63702958 0.81 ENST00000544088.6
serpin family B member 11
chr4_+_85827891 0.79 ENST00000514229.5
Rho GTPase activating protein 24
chr1_+_192575765 0.79 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chrX_+_106693838 0.76 ENST00000324342.7
ring finger protein 128
chr13_-_46182136 0.76 ENST00000323076.7
lymphocyte cytosolic protein 1
chr2_+_210477676 0.75 ENST00000673510.1
ENST00000673630.1
ENST00000430249.7
carbamoyl-phosphate synthase 1
chr2_-_88861920 0.75 ENST00000390242.2
immunoglobulin kappa joining 1
chr11_-_119101814 0.73 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr3_-_187291882 0.73 ENST00000392470.6
ENST00000169293.10
ENST00000439271.1
ENST00000392472.6
ENST00000392475.2
mannan binding lectin serine peptidase 1
chr2_+_233917371 0.72 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr7_+_142544199 0.71 ENST00000611462.1
T cell receptor beta variable 10-3
chr11_+_60914139 0.70 ENST00000227525.8
transmembrane protein 109
chr9_+_27109393 0.69 ENST00000406359.8
TEK receptor tyrosine kinase
chrX_+_106693751 0.67 ENST00000418562.5
ring finger protein 128
chr2_+_210477708 0.67 ENST00000673711.1
carbamoyl-phosphate synthase 1
chr17_-_64390852 0.65 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr14_-_106038355 0.65 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr10_-_22003678 0.65 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr5_-_170297746 0.64 ENST00000046794.10
lymphocyte cytosolic protein 2
chr6_+_131637296 0.63 ENST00000358229.6
ENST00000357639.8
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr7_-_7640971 0.63 ENST00000396682.6
replication protein A3
chr3_+_186842687 0.62 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr9_-_83063135 0.62 ENST00000376447.4
RAS and EF-hand domain containing
chr2_-_75518697 0.61 ENST00000452003.1
eva-1 homolog A, regulator of programmed cell death
chr16_+_82034978 0.61 ENST00000563491.5
hydroxysteroid 17-beta dehydrogenase 2
chr4_+_107824555 0.60 ENST00000394684.8
sphingomyelin synthase 2
chr17_+_9825906 0.60 ENST00000262441.10
glucagon like peptide 2 receptor
chr11_-_26567087 0.60 ENST00000436318.6
ENST00000281268.12
mucin 15, cell surface associated
chr13_+_48976597 0.59 ENST00000541916.5
fibronectin type III domain containing 3A
chr1_+_196977550 0.58 ENST00000256785.5
complement factor H related 5
chr12_+_56080155 0.57 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr15_-_55408467 0.57 ENST00000310958.10
cell cycle progression 1
chr21_+_42653734 0.56 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr10_-_100185993 0.55 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr10_-_93482287 0.55 ENST00000371489.5
myoferlin
chr4_+_85827745 0.55 ENST00000509300.5
Rho GTPase activating protein 24
chr6_-_49964160 0.50 ENST00000322066.4
defensin beta 114
chr9_-_73038711 0.49 ENST00000446946.1
aldehyde dehydrogenase 1 family member A1
chr8_-_92965988 0.48 ENST00000517751.5
ENST00000524107.5
triple QxxK/R motif containing
chr10_-_119536533 0.48 ENST00000392865.5
regulator of G protein signaling 10
chr14_+_20781139 0.48 ENST00000304677.3
ribonuclease A family member k6
chr7_-_155812454 0.48 ENST00000297261.7
sonic hedgehog signaling molecule
chr4_+_155854758 0.47 ENST00000506072.5
ENST00000507590.5
tryptophan 2,3-dioxygenase
chr3_-_121660892 0.46 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr15_+_58410543 0.46 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr4_-_68951763 0.45 ENST00000251566.9
UDP glucuronosyltransferase family 2 member A3
chr12_+_56080126 0.44 ENST00000411731.6
erb-b2 receptor tyrosine kinase 3
chr17_-_74776323 0.43 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
N-acetyltransferase 9 (putative)
chr9_+_27109135 0.42 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr12_+_20815672 0.42 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr22_+_41699492 0.42 ENST00000401548.8
ENST00000540833.1
meiotic double-stranded break formation protein 1
chr12_+_104286881 0.42 ENST00000526691.5
ENST00000531691.5
ENST00000526390.5
ENST00000531689.5
thioredoxin reductase 1
chr13_-_110242694 0.41 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr6_+_25652201 0.41 ENST00000612225.4
ENST00000377961.3
secretagogin, EF-hand calcium binding protein
chr6_-_26199272 0.40 ENST00000650491.1
ENST00000635200.1
ENST00000341023.2
novel protein
H2A clustered histone 7
chr3_-_46208304 0.39 ENST00000296140.4
C-C motif chemokine receptor 1
chr6_+_85449584 0.39 ENST00000369651.7
5'-nucleotidase ecto
chrX_-_1212634 0.38 ENST00000381567.8
ENST00000381566.6
ENST00000400841.8
cytokine receptor like factor 2
chr6_-_134950081 0.38 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
aldehyde dehydrogenase 8 family member A1
chr9_+_27109200 0.38 ENST00000380036.10
TEK receptor tyrosine kinase
chr6_+_25754699 0.36 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr15_-_55408245 0.36 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr7_+_141995872 0.35 ENST00000497673.5
ENST00000620571.1
ENST00000475668.6
maltase-glucoamylase
chr20_+_6006039 0.34 ENST00000452938.5
ENST00000378863.9
cardiolipin synthase 1
chr18_+_44680875 0.34 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr8_-_70245343 0.33 ENST00000519724.1
nuclear receptor coactivator 2
chr11_-_74731148 0.33 ENST00000263671.9
ENST00000528789.1
chordin like 2
chr1_+_119711884 0.33 ENST00000641947.1
ENST00000641074.1
ENST00000641115.1
ENST00000369409.9
ENST00000641023.2
ENST00000641272.1
phosphoglycerate dehydrogenase
chr1_+_86547070 0.32 ENST00000370563.3
chloride channel accessory 4
chr2_-_20051610 0.32 ENST00000175091.5
lysosomal protein transmembrane 4 alpha
chr4_-_137532452 0.32 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr3_+_23805941 0.31 ENST00000306627.8
ENST00000346855.7
ubiquitin conjugating enzyme E2 E1
chr6_-_30161200 0.31 ENST00000449742.7
tripartite motif containing 10
chr6_-_26123910 0.31 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr1_+_74733144 0.31 ENST00000457880.6
ENST00000370867.8
tRNA-yW synthesizing protein 3 homolog
chr19_-_14778552 0.30 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr4_-_26490453 0.30 ENST00000295589.4
cholecystokinin A receptor
chr16_-_21652598 0.30 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr2_+_157257687 0.29 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr7_+_77696423 0.29 ENST00000334955.13
round spermatid basic protein 1 like
chr19_-_51028015 0.29 ENST00000319720.11
kallikrein related peptidase 11
chr14_+_23095491 0.27 ENST00000319074.6
ENST00000554203.1
chromosome 14 open reading frame 119
chr14_+_73239599 0.27 ENST00000554301.5
ENST00000555445.5
papilin, proteoglycan like sulfated glycoprotein
chr1_-_152089062 0.26 ENST00000368806.2
trichohyalin like 1
chr6_+_33075952 0.25 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr11_+_64234569 0.25 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr2_+_117814648 0.25 ENST00000263239.7
DEAD-box helicase 18
chrX_+_22136552 0.25 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr12_+_104287015 0.25 ENST00000529546.5
ENST00000529751.1
ENST00000528079.6
ENST00000526580.5
thioredoxin reductase 1
chr8_+_31639291 0.25 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr6_+_26199509 0.24 ENST00000356530.5
H2B clustered histone 7
chr8_-_13276491 0.24 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr1_-_217631034 0.24 ENST00000366934.3
ENST00000366935.8
G-patch domain containing 2
chr3_+_133784020 0.24 ENST00000466490.7
SRP receptor subunit beta
chr15_-_60402873 0.22 ENST00000557904.5
annexin A2
chr6_+_25652272 0.22 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr11_-_74731385 0.22 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr14_+_55129242 0.21 ENST00000254301.14
ENST00000554715.1
galectin 3
chr19_+_40775511 0.20 ENST00000263369.4
ENST00000597140.5
MIA SH3 domain containing
chr12_+_107318395 0.20 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr9_+_129081098 0.20 ENST00000406974.7
ENST00000372546.9
dolichyldiphosphatase 1
chr13_+_27424583 0.20 ENST00000381140.10
general transcription factor IIIA
chr11_-_105023136 0.20 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr13_-_102773732 0.19 ENST00000376022.5
ENST00000376021.8
testis expressed 30
chr1_+_65147514 0.19 ENST00000545314.5
adenylate kinase 4
chr4_-_39977836 0.18 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr17_-_75667088 0.18 ENST00000578201.5
ENST00000423245.6
ENST00000317905.10
RecQ like helicase 5
chr4_+_71236029 0.18 ENST00000639096.1
ENST00000638464.1
solute carrier family 4 member 4
chr1_+_54980610 0.18 ENST00000371268.4
transmembrane protein 61
chr12_-_10435940 0.17 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
killer cell lectin like receptor C2
novel protein
chr8_+_31639222 0.17 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr3_-_186544377 0.17 ENST00000307944.6
crystallin gamma S
chr5_-_115625972 0.17 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr1_-_205994439 0.17 ENST00000617991.4
RAB7B, member RAS oncogene family
chr10_+_27532521 0.17 ENST00000683924.1
RAB18, member RAS oncogene family
chr17_-_72992933 0.17 ENST00000582769.5
solute carrier family 39 member 11
chr1_+_156126160 0.16 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr12_+_25052634 0.16 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr10_+_92834594 0.16 ENST00000371552.8
exocyst complex component 6
chr9_+_127397129 0.16 ENST00000610552.4
solute carrier family 2 member 8
chr2_+_227472363 0.16 ENST00000409315.5
ENST00000373671.7
ENST00000409171.5
ArfGAP with FG repeats 1
chr18_-_55423757 0.15 ENST00000675707.1
transcription factor 4
chr17_-_49678074 0.15 ENST00000505581.5
ENST00000504102.6
ENST00000514121.6
ENST00000393328.6
ENST00000509079.6
ENST00000347630.6
speckle type BTB/POZ protein
chr3_-_147406760 0.15 ENST00000491672.5
Zic family member 4
chr10_+_70404129 0.15 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr2_-_133568393 0.15 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCK associated protein 5
chr3_-_194468227 0.14 ENST00000446356.1
ATPase 13A3
chr17_-_40799939 0.14 ENST00000306658.8
keratin 28
chrX_+_1591590 0.14 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr5_-_135399863 0.13 ENST00000510038.1
ENST00000304332.8
macroH2A.1 histone
chr17_-_40665121 0.13 ENST00000394052.5
keratin 222
chr1_+_171557845 0.13 ENST00000644916.1
proline rich coiled-coil 2C
chr9_+_127397153 0.13 ENST00000451404.5
ENST00000373371.8
solute carrier family 2 member 8
chr5_+_120531464 0.13 ENST00000505123.5
proline rich 16
chr2_+_27032938 0.13 ENST00000238788.14
ENST00000404032.7
transmembrane protein 214
chr13_-_102773762 0.12 ENST00000376032.9
ENST00000376029.3
testis expressed 30
chr19_+_18557762 0.12 ENST00000539106.5
ENST00000540691.5
KxDL motif containing 1
chr16_-_20698890 0.12 ENST00000523065.1
acyl-CoA synthetase medium chain family member 1
chr18_+_74499329 0.12 ENST00000583216.5
ENST00000581912.1
ENST00000582589.5
carnosine dipeptidase 2
chr4_-_67963441 0.12 ENST00000508048.6
transmembrane serine protease 11A
chr12_+_81078035 0.11 ENST00000261206.7
ENST00000548058.6
acyl-CoA synthetase short chain family member 3
chr6_+_151239951 0.11 ENST00000402676.7
A-kinase anchoring protein 12
chr6_-_2750912 0.11 ENST00000274643.9
myosin light chain kinase family member 4
chr7_+_141995826 0.10 ENST00000549489.6
maltase-glucoamylase
chr7_-_128361604 0.10 ENST00000489835.6
ENST00000489517.1
ENST00000446477.6
ENST00000535159.5
ENST00000495931.1
proline rich transmembrane protein 4
chr2_+_171453122 0.10 ENST00000611110.4
ENST00000339506.7
DDB1 and CUL4 associated factor 17
chr3_-_79767987 0.10 ENST00000464233.6
roundabout guidance receptor 1
chr20_-_49188360 0.10 ENST00000371828.7
ENST00000340954.11
ENST00000347458.9
ENST00000360426.8
ENST00000371792.5
ENST00000371802.5
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chr12_+_71664352 0.09 ENST00000547843.1
THAP domain containing 2
chr19_-_50837213 0.09 ENST00000326856.8
kallikrein related peptidase 15
chr19_+_57633161 0.09 ENST00000541801.5
ENST00000347302.7
ENST00000240731.5
ENST00000254182.11
ENST00000391703.3
zinc finger protein 211
chrX_-_101932074 0.09 ENST00000651725.1
zinc finger matrin-type 1
chr7_-_32490361 0.09 ENST00000410044.5
ENST00000450169.7
ENST00000409987.5
ENST00000409782.5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_241350087 0.08 ENST00000451310.1
septin 2
chr6_-_169253835 0.08 ENST00000649844.1
ENST00000617924.6
thrombospondin 2
chr13_+_23570370 0.08 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr1_-_157552455 0.08 ENST00000368190.7
ENST00000368189.3
Fc receptor like 5
chr17_+_54938848 0.08 ENST00000574318.1
target of myb1 like 1 membrane trafficking protein
chr4_-_69653223 0.08 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus
chr4_-_48780242 0.07 ENST00000507711.5
ENST00000358350.9
FRY like transcription coactivator
chr22_-_17774482 0.07 ENST00000399765.5
ENST00000614949.4
ENST00000399767.6
BH3 interacting domain death agonist
chr6_-_27890818 0.07 ENST00000359303.4
H3 clustered histone 12
chr12_-_15221394 0.07 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chr19_-_52171643 0.07 ENST00000597065.1
zinc finger protein 836

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.4 1.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.3 2.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.3 0.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 0.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 0.6 GO:0072244 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 1.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 2.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0072011 glomerular endothelium development(GO:0072011)
0.1 0.7 GO:0050955 thermoception(GO:0050955)
0.1 0.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 1.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.3 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:0052363 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:2000521 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521)
0.0 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 1.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.4 GO:0042133 neurotransmitter metabolic process(GO:0042133)
0.0 0.6 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0050925 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.4 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 1.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.4 GO:0030449 regulation of complement activation(GO:0030449)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0072558 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 3.9 GO:0005902 microvillus(GO:0005902)
0.0 1.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.3 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 0.7 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 1.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.5 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.2 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 2.3 GO:0008430 selenium binding(GO:0008430)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780) 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters