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avrg: Illumina Body Map 2 (GSE30611)

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Results for HOXB4_LHX9

Z-value: 1.26

Motif logo

Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
ENSG00000182742.6 HOXB4
ENSG00000143355.16 LHX9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX9hg38_v1_chr1_+_197912462_1979125050.318.5e-02Click!
HOXB4hg38_v1_chr17_-_48578341_48578356-0.222.2e-01Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_26195313 4.62 ENST00000422622.3
sarcospan
chr18_+_58341038 4.58 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr19_+_53962925 3.58 ENST00000270458.4
calcium voltage-gated channel auxiliary subunit gamma 8
chr4_+_118888829 3.28 ENST00000448416.6
ENST00000307142.9
ENST00000429713.7
synaptopodin 2
chr4_+_118888918 3.19 ENST00000434046.6
synaptopodin 2
chr12_+_101594849 3.03 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr12_+_26195543 2.99 ENST00000242729.7
sarcospan
chrX_+_10158448 2.77 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr4_+_168497066 2.60 ENST00000261509.10
palladin, cytoskeletal associated protein
chr9_+_93234923 2.52 ENST00000411624.5
WNK lysine deficient protein kinase 2
chr11_-_129024157 2.48 ENST00000392657.7
Rho GTPase activating protein 32
chr17_+_7407838 2.30 ENST00000302926.7
neuroligin 2
chr16_+_3134923 2.29 ENST00000574902.5
ENST00000396878.8
zinc finger protein 213
chr5_-_35938572 2.13 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr1_-_66801276 2.10 ENST00000304526.3
insulin like 5
chr4_+_168497044 2.10 ENST00000505667.6
palladin, cytoskeletal associated protein
chrX_-_21758097 2.04 ENST00000379494.4
small muscle protein X-linked
chr2_+_181985846 2.04 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr10_+_18400562 1.98 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr5_+_36606355 1.88 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr18_-_36798482 1.88 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr13_-_35855758 1.86 ENST00000615680.4
doublecortin like kinase 1
chrX_-_21758021 1.84 ENST00000646008.1
small muscle protein X-linked
chr17_-_44915486 1.83 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chr20_+_45416551 1.83 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr3_-_165078480 1.76 ENST00000264382.8
sucrase-isomaltase
chr10_+_18260715 1.73 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr17_+_41966787 1.71 ENST00000393892.8
ENST00000587679.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr17_+_68515399 1.69 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_+_128883114 1.68 ENST00000421865.3
ENST00000618192.4
ENST00000617695.4
laminin subunit alpha 2
chr10_-_13001705 1.68 ENST00000378825.5
coiled-coil domain containing 3
chr11_-_107858777 1.64 ENST00000525815.6
solute carrier family 35 member F2
chr16_+_28878480 1.59 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr12_-_10826358 1.58 ENST00000240619.2
taste 2 receptor member 10
chr3_-_20012250 1.53 ENST00000389050.5
protein phosphatase 2C like domain containing 1
chr15_-_72231583 1.53 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr11_-_107858561 1.52 ENST00000375682.8
solute carrier family 35 member F2
chr2_+_27663880 1.51 ENST00000618046.4
ENST00000613517.4
solute carrier family 4 member 1 adaptor protein
chr2_+_27663441 1.50 ENST00000326019.10
ENST00000613058.4
solute carrier family 4 member 1 adaptor protein
chr12_-_25195074 1.45 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr15_+_21579912 1.45 ENST00000628444.1
long intergenic non-protein coding RNA 2203
chr1_-_230869564 1.43 ENST00000470540.5
chromosome 1 open reading frame 198
chr13_-_75366973 1.42 ENST00000648194.1
TBC1 domain family member 4
chr7_-_88226987 1.41 ENST00000394641.7
sorcin
chr8_+_104223320 1.40 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr10_-_73655984 1.39 ENST00000394810.3
synaptopodin 2 like
chr18_-_26863187 1.36 ENST00000440832.7
aquaporin 4
chr5_+_141177790 1.36 ENST00000239444.4
ENST00000623995.1
protocadherin beta 8
novel transcript
chr4_-_139280179 1.35 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr8_-_41309434 1.33 ENST00000220772.8
secreted frizzled related protein 1
chr7_-_88226965 1.32 ENST00000490437.5
ENST00000431660.5
sorcin
chr2_-_74392025 1.31 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr20_-_57690624 1.26 ENST00000414037.5
prostate transmembrane protein, androgen induced 1
chr5_-_177462379 1.23 ENST00000512501.1
drebrin 1
chr5_+_1225379 1.20 ENST00000324642.4
solute carrier family 6 member 18
chr3_-_58627567 1.20 ENST00000649301.1
family with sequence similarity 107 member A
chr2_-_74391780 1.18 ENST00000421392.1
ENST00000437375.1
dynactin subunit 1
chr21_+_32298849 1.18 ENST00000303645.10
melanocortin 2 receptor accessory protein
chr14_-_80231052 1.17 ENST00000557010.5
iodothyronine deiodinase 2
chr19_+_35748549 1.15 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr6_-_110179995 1.14 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr19_-_42427379 1.14 ENST00000244289.9
lipase E, hormone sensitive type
chr1_-_72100930 1.12 ENST00000306821.3
neuronal growth regulator 1
chr5_-_41794211 1.11 ENST00000512084.5
3-oxoacid CoA-transferase 1
chr14_+_32329341 1.11 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr17_-_41586887 1.10 ENST00000167586.7
keratin 14
chr9_+_121567057 1.09 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr1_-_211134135 1.06 ENST00000638983.1
ENST00000271751.10
ENST00000639952.1
novel protein
potassium voltage-gated channel subfamily H member 1
chr6_+_28259285 1.06 ENST00000343684.4
NFKB activating protein like
chrX_-_143517473 1.05 ENST00000370503.2
SPANX family member N3
chr8_-_30812773 1.05 ENST00000221138.9
protein phosphatase 2 catalytic subunit beta
chr1_-_211134061 1.04 ENST00000639602.1
ENST00000638498.1
ENST00000367007.5
novel protein
potassium voltage-gated channel subfamily H member 1
chr13_+_35476740 1.03 ENST00000537702.5
neurobeachin
chr17_+_41966814 1.03 ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr4_-_119322128 1.03 ENST00000274024.4
fatty acid binding protein 2
chr2_-_74391837 1.01 ENST00000417090.1
ENST00000409868.5
ENST00000680606.1
dynactin subunit 1
chr7_-_80919017 1.00 ENST00000265361.8
semaphorin 3C
chr1_+_212791828 0.99 ENST00000532324.5
ENST00000530441.5
ENST00000526641.5
ENST00000531963.5
ENST00000366973.8
ENST00000366974.9
ENST00000526997.5
ENST00000488246.6
TatD DNase domain containing 3
chr11_+_5689691 0.99 ENST00000425490.5
tripartite motif containing 22
chr2_+_181986015 0.98 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr1_-_109042093 0.98 ENST00000369962.8
ENST00000357672.7
ENST00000531337.1
ENST00000529074.1
ENST00000369965.8
WD repeat domain 47
chrX_-_139708190 0.98 ENST00000414978.5
ENST00000519895.5
MCF.2 cell line derived transforming sequence
chr3_+_148991408 0.98 ENST00000627418.2
ENST00000296048.10
ENST00000483267.5
ENST00000345003.9
ENST00000484197.5
glycogenin 1
chr8_-_30812867 0.97 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr17_+_41966739 0.97 ENST00000472031.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr13_+_76948500 0.97 ENST00000377462.6
aconitate decarboxylase 1
chr6_+_29657120 0.96 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chrX_+_73563190 0.96 ENST00000373504.10
ENST00000373502.9
cysteine rich hydrophobic domain 1
chr19_-_43883964 0.96 ENST00000587539.2
zinc finger protein 404
chr18_-_3219849 0.96 ENST00000261606.11
myomesin 1
chr7_+_120988683 0.95 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr5_-_20575850 0.94 ENST00000507958.5
cadherin 18
chr14_+_30577752 0.93 ENST00000547532.5
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr3_+_28349146 0.93 ENST00000420223.5
zinc finger CW-type and PWWP domain containing 2
chr17_+_58755821 0.93 ENST00000308249.4
protein phosphatase, Mg2+/Mn2+ dependent 1E
chr2_+_26401909 0.92 ENST00000288710.7
dynein regulatory complex subunit 1
chr8_-_100559702 0.92 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46
chr4_-_46124046 0.92 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr4_+_157076119 0.90 ENST00000541722.5
ENST00000264428.9
ENST00000512619.5
glycine receptor beta
chr5_+_175861628 0.90 ENST00000509837.5
complexin 2
chr6_+_54099565 0.89 ENST00000511678.5
muscular LMNA interacting protein
chr3_+_111998739 0.89 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr12_-_109021015 0.88 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr2_+_186694007 0.87 ENST00000304698.10
family with sequence similarity 171 member B
chr5_-_140346596 0.87 ENST00000230990.7
heparin binding EGF like growth factor
chr20_+_15196834 0.87 ENST00000402914.5
mono-ADP ribosylhydrolase 2
chr20_+_33217325 0.86 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr2_-_206718396 0.85 ENST00000452335.2
dystrotelin
chr3_-_161105224 0.85 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_-_121765104 0.84 ENST00000643802.2
ENST00000643663.2
small integral membrane protein 43
chr10_-_104085847 0.82 ENST00000648076.2
collagen type XVII alpha 1 chain
chr1_+_10450004 0.81 ENST00000377049.4
cortistatin
chr5_+_67004618 0.81 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_+_111998915 0.81 ENST00000478951.6
transgelin 3
chr6_-_110179855 0.81 ENST00000368938.5
WASP family member 1
chr10_+_24466487 0.80 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr1_+_77918128 0.79 ENST00000342754.5
nexilin F-actin binding protein
chr4_+_140343443 0.79 ENST00000338517.8
ENST00000394203.7
ENST00000506322.5
short coiled-coil protein
chr15_+_22015233 0.78 ENST00000639059.1
ENST00000640156.1
novel protein
novel transcript
chr3_+_111999189 0.78 ENST00000455401.6
transgelin 3
chr5_-_74641419 0.77 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr19_-_14835162 0.76 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr4_+_168631597 0.76 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chr13_+_77741212 0.76 ENST00000441784.5
SLAIN motif family member 1
chr9_-_96778053 0.76 ENST00000375231.5
ENST00000223428.9
zinc finger protein 510
chr15_+_62561361 0.75 ENST00000561311.5
talin 2
chr11_-_117316230 0.75 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr1_+_166989089 0.75 ENST00000367870.6
maelstrom spermatogenic transposon silencer
chr6_+_29657085 0.74 ENST00000376917.8
ENST00000376894.8
myelin oligodendrocyte glycoprotein
chr16_-_81220370 0.74 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chrX_-_139965510 0.74 ENST00000370540.2
chromosome X open reading frame 66
chr17_-_47189176 0.73 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
cell division cycle 27
chr22_-_32255344 0.73 ENST00000266086.6
solute carrier family 5 member 4
chrX_+_85003863 0.72 ENST00000373173.7
apolipoprotein O like
chrX_-_13817027 0.72 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr2_-_27663817 0.72 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr2_-_142131004 0.72 ENST00000434794.1
ENST00000389484.8
LDL receptor related protein 1B
chr5_-_126595237 0.72 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr2_-_27663594 0.71 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr16_-_66730216 0.70 ENST00000569320.5
dynein cytoplasmic 1 light intermediate chain 2
chr16_+_14708944 0.70 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chrX_+_43656289 0.69 ENST00000338702.4
monoamine oxidase A
chr1_+_174700413 0.69 ENST00000529145.6
ENST00000325589.9
RAB GTPase activating protein 1 like
chr12_+_26011713 0.69 ENST00000542004.5
Ras association domain family member 8
chr5_+_90474848 0.69 ENST00000651687.1
RNA polymerase III subunit G
chr6_+_29656993 0.69 ENST00000376888.6
myelin oligodendrocyte glycoprotein
chr14_+_103385374 0.68 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
microtubule affinity regulating kinase 3
chr6_+_54099538 0.68 ENST00000447836.6
muscular LMNA interacting protein
chr7_+_23106267 0.67 ENST00000409689.5
ENST00000410047.1
kelch like family member 7
chr7_+_123601815 0.66 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr12_+_64404338 0.66 ENST00000332707.10
exportin for tRNA
chrX_-_21658324 0.66 ENST00000379499.3
kelch like family member 34
chr2_-_127526444 0.65 ENST00000295321.9
interacts with SUPT6H, CTD assembly factor 1
chr3_-_157503375 0.65 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr1_+_76867469 0.64 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chrX_-_16869840 0.64 ENST00000380084.8
RB binding protein 7, chromatin remodeling factor
chr1_-_212791762 0.64 ENST00000626725.1
ENST00000366977.8
ENST00000366976.3
NSL1 component of MIS12 kinetochore complex
chr17_+_20073538 0.63 ENST00000681116.1
ENST00000680572.1
ENST00000680604.1
ENST00000681875.1
ENST00000679058.1
sperm antigen with calponin homology and coiled-coil domains 1
chr4_-_159035226 0.63 ENST00000434826.3
chromosome 4 open reading frame 45
chr4_-_89836213 0.63 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr3_-_142000353 0.63 ENST00000499676.5
transcription factor Dp-2
chr17_+_47651061 0.63 ENST00000540627.5
karyopherin subunit beta 1
chr6_+_47781982 0.62 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
opsin 5
chr10_+_99732211 0.62 ENST00000370476.10
ENST00000370472.4
cutC copper transporter
chr16_+_3135121 0.62 ENST00000576416.5
ENST00000416391.6
zinc finger protein 213
chr1_-_109041986 0.61 ENST00000400794.7
ENST00000528747.1
ENST00000361054.7
WD repeat domain 47
chr2_+_101839815 0.61 ENST00000421882.5
mitogen-activated protein kinase kinase kinase kinase 4
chr9_+_12695702 0.61 ENST00000381136.2
tyrosinase related protein 1
chr10_-_114658268 0.61 ENST00000649363.1
ENST00000277895.9
actin binding LIM protein 1
chr3_-_157503339 0.61 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr7_+_123601836 0.61 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr20_-_31390483 0.60 ENST00000376315.2
defensin beta 119
chr17_+_68249200 0.60 ENST00000577985.5
archaelysin family metallopeptidase 2
chr17_+_50746614 0.60 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr13_-_23433735 0.60 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr8_+_49911604 0.59 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr3_-_149377637 0.59 ENST00000305366.8
transmembrane 4 L six family member 1
chr12_+_26195647 0.58 ENST00000535504.1
sarcospan
chr2_+_132416795 0.58 ENST00000329321.4
G protein-coupled receptor 39
chr17_+_69502397 0.58 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr6_+_29111560 0.58 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr12_+_80716906 0.57 ENST00000228644.4
myogenic factor 5
chr10_+_62049211 0.56 ENST00000309334.5
AT-rich interaction domain 5B
chr10_+_96129707 0.56 ENST00000316045.9
zinc finger protein 518A
chrX_+_1591590 0.55 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr11_-_95923763 0.55 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr18_-_35290184 0.55 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
zinc finger and SCAN domain containing 30
novel transcript
chr4_+_133149278 0.55 ENST00000264360.7
protocadherin 10
chr20_+_43559060 0.55 ENST00000485914.2
serum/glucocorticoid regulated kinase 2
chr4_+_155666718 0.55 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chr2_-_40453438 0.54 ENST00000455476.5
solute carrier family 8 member A1
chr14_+_71933116 0.54 ENST00000553530.5
ENST00000556437.5
regulator of G protein signaling 6
chr3_+_156142962 0.54 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr13_+_111184932 0.54 ENST00000467053.5
Rho guanine nucleotide exchange factor 7
chr4_+_70154220 0.54 ENST00000344526.10
proline rich 27
chr17_+_1771688 0.53 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr11_-_101129806 0.53 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chrX_+_101408198 0.53 ENST00000316594.6
heterogeneous nuclear ribonucleoprotein H2
chr20_-_31390580 0.53 ENST00000339144.3
ENST00000376321.4
defensin beta 119
chr8_-_115492221 0.53 ENST00000518018.1
transcriptional repressor GATA binding 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.5 0.5 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.4 1.3 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.4 3.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.4 3.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 4.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 2.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.3 2.7 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.3 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.3 1.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 0.6 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.2 1.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.6 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 1.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.2 2.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 1.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 5.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.7 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 4.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 0.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.2 1.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.9 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 1.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.7 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 2.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 1.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 1.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.7 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.8 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 3.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.5 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.6 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.3 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.6 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 1.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 8.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 1.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 1.1 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.1 1.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 4.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 1.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.3 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 3.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.5 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.4 GO:0006833 water transport(GO:0006833)
0.0 0.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:2000394 regulation of GTP binding(GO:1904424) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.9 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.6 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 12.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633) positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.5 GO:0006706 steroid catabolic process(GO:0006706)
0.0 1.1 GO:0007631 feeding behavior(GO:0007631)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.6 GO:0016577 histone demethylation(GO:0016577)
0.0 0.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0005927 muscle tendon junction(GO:0005927)
0.4 1.5 GO:1902912 pyruvate kinase complex(GO:1902912)
0.3 2.7 GO:0044326 dendritic spine neck(GO:0044326)
0.3 0.8 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 0.8 GO:0030849 autosome(GO:0030849)
0.2 1.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 3.5 GO:0005869 dynactin complex(GO:0005869)
0.2 1.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 0.8 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 1.1 GO:1990032 parallel fiber(GO:1990032)
0.2 9.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 0.5 GO:0060187 cell pole(GO:0060187)
0.1 2.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 3.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0070939 Dsl1p complex(GO:0070939)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 3.0 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 2.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0035363 histone locus body(GO:0035363)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 5.3 GO:0002102 podosome(GO:0002102)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 7.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 1.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 3.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0044207 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.1 1.2 GO:0042641 actomyosin(GO:0042641)
0.1 1.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 5.0 GO:0005771 multivesicular body(GO:0005771)
0.0 1.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.5 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 7.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 3.8 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 2.7 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.6 1.8 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 15.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 1.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.4 1.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 3.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 2.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 1.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.0 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 1.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 0.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.5 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.2 3.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 4.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 1.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.1 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 2.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.4 GO:0015250 water channel activity(GO:0015250)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 3.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 4.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0070402 NADPH binding(GO:0070402)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.0 GO:0070628 proteasome binding(GO:0070628)
0.0 1.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0030547 receptor inhibitor activity(GO:0030547)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 4.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 3.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 3.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 3.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 2.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants