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avrg: Illumina Body Map 2 (GSE30611)
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Results for HOXC10_HOXD13
Z-value: 1.87
Motif logo
Transcription factors associated with HOXC10_HOXD13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC10
|
ENSG00000180818.5 | HOXC10 |
|
HOXD13
|
ENSG00000128714.6 | HOXD13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXD13 | hg38_v1_chr2_+_176092715_176092729 | 0.63 | 1.1e-04 | Click! |
| HOXC10 | hg38_v1_chr12_+_53985138_53985183 | 0.21 | 2.5e-01 | Click! |
Activity profile of HOXC10_HOXD13 motif
Sorted Z-values of HOXC10_HOXD13 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC10_HOXD13
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.8 | GO:1904237 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 1.8 | 7.4 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 1.8 | 5.4 | GO:1901877 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 1.0 | 2.9 | GO:1904397 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 0.9 | 2.6 | GO:1900135 | positive regulation of renin secretion into blood stream(GO:1900135) |
| 0.9 | 3.4 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.6 | 3.7 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 0.6 | 3.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.6 | 3.4 | GO:0035602 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) |
| 0.6 | 10.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.5 | 2.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.5 | 4.1 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.4 | 5.2 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.4 | 1.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.4 | 1.8 | GO:1902159 | regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) |
| 0.4 | 1.8 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
| 0.4 | 1.1 | GO:0015847 | putrescine transport(GO:0015847) |
| 0.3 | 1.0 | GO:2000276 | negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793) |
| 0.3 | 2.0 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 0.3 | 1.0 | GO:0061033 | secretion by lung epithelial cell involved in lung growth(GO:0061033) |
| 0.3 | 1.3 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.3 | 1.9 | GO:0097319 | fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.3 | 0.6 | GO:2000974 | negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.3 | 1.9 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) |
| 0.3 | 1.2 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.3 | 1.2 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.3 | 1.1 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.3 | 1.4 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.3 | 2.8 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.3 | 1.3 | GO:0003219 | cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032) |
| 0.3 | 1.8 | GO:1902731 | negative regulation of chondrocyte proliferation(GO:1902731) |
| 0.2 | 1.0 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.2 | 1.0 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.2 | 1.4 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.2 | 3.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.2 | 0.7 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.2 | 3.3 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.2 | 0.6 | GO:1990451 | cellular stress response to acidic pH(GO:1990451) |
| 0.2 | 3.0 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.2 | 7.5 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.2 | 0.6 | GO:0046247 | tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247) |
| 0.2 | 1.8 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.2 | 0.6 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
| 0.2 | 3.3 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.2 | 1.0 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 0.2 | 0.6 | GO:0090264 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237) |
| 0.2 | 0.8 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.2 | 0.7 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.2 | 0.9 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.2 | 0.5 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.2 | 0.8 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.2 | 1.5 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 1.6 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.2 | 4.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 0.5 | GO:0021757 | caudate nucleus development(GO:0021757) putamen development(GO:0021758) |
| 0.2 | 0.9 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.2 | 3.1 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.2 | 1.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 0.6 | GO:0051582 | positive regulation of neurotransmitter uptake(GO:0051582) |
| 0.2 | 0.5 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.1 | 2.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.1 | 0.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 0.8 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.1 | 1.0 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 0.1 | 1.0 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 0.8 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 1.4 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 3.4 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 1.0 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.1 | 1.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 1.0 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.1 | 1.7 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 2.3 | GO:0010578 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.1 | 2.1 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 0.5 | GO:0060529 | squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) |
| 0.1 | 1.3 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 0.9 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.1 | 0.5 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 1.3 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 2.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 3.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.5 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.1 | 0.5 | GO:1904209 | maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.1 | 0.3 | GO:1903515 | calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515) |
| 0.1 | 0.7 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.1 | 0.4 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.1 | 0.7 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 0.4 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 1.2 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 0.6 | GO:0018032 | protein amidation(GO:0018032) |
| 0.1 | 2.0 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.1 | 0.8 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 0.5 | GO:0061181 | regulation of chondrocyte development(GO:0061181) |
| 0.1 | 0.9 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.7 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.1 | 1.1 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.3 | GO:1901382 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
| 0.1 | 0.8 | GO:0033007 | negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305) |
| 0.1 | 0.8 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.1 | 0.6 | GO:0071799 | response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799) |
| 0.1 | 0.6 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.1 | 0.6 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 0.4 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.1 | 1.6 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 0.4 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.1 | 0.3 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.1 | 0.5 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 1.3 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 1.1 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.1 | 1.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 0.2 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 0.8 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.1 | 0.7 | GO:0033292 | T-tubule organization(GO:0033292) protein localization to T-tubule(GO:0036371) |
| 0.1 | 1.0 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 0.2 | GO:0034476 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 0.1 | 0.5 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 1.5 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.8 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.1 | 0.3 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.1 | 1.5 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 1.5 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 1.6 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.4 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.6 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 0.3 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.5 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.8 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.0 | 1.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 1.7 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.6 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.9 | GO:0001946 | lymphangiogenesis(GO:0001946) |
| 0.0 | 1.7 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.2 | GO:0002426 | immunoglobulin production in mucosal tissue(GO:0002426) |
| 0.0 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.1 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) |
| 0.0 | 0.9 | GO:0051775 | response to redox state(GO:0051775) |
| 0.0 | 1.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.0 | 0.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.1 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.0 | 0.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.3 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.0 | 1.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.2 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.0 | 0.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.0 | 0.2 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.0 | 0.4 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 2.0 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
| 0.0 | 0.4 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.3 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.0 | 0.6 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.0 | 0.4 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.0 | 0.2 | GO:0034164 | negative regulation of toll-like receptor 9 signaling pathway(GO:0034164) |
| 0.0 | 1.0 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.5 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.0 | 0.3 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.0 | 0.3 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 1.2 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.5 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.0 | 1.4 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.0 | 0.3 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
| 0.0 | 0.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.1 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.0 | 3.2 | GO:0051782 | negative regulation of cell division(GO:0051782) |
| 0.0 | 0.1 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.0 | 0.1 | GO:0033319 | UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320) |
| 0.0 | 0.1 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.0 | 0.2 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.0 | 0.1 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.0 | 0.6 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 2.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.3 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 0.6 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 0.2 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.0 | 0.4 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 1.0 | GO:0043278 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.0 | 0.3 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.8 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 1.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.5 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 1.5 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.0 | 0.8 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.4 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.0 | 0.2 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.0 | 0.7 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.0 | 0.1 | GO:0035513 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.5 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 0.0 | 0.7 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 1.0 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 1.9 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.0 | 1.1 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.2 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.5 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.0 | 0.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 0.1 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.0 | 0.8 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.0 | 0.4 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 0.5 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.0 | 0.9 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 0.1 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.0 | 0.6 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 2.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.4 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 1.0 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 0.1 | GO:2000670 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.0 | 0.1 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.0 | 0.3 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 0.3 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.0 | 0.1 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.0 | 0.1 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.0 | 0.2 | GO:0009629 | response to gravity(GO:0009629) |
| 0.0 | 0.6 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.0 | 0.3 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.0 | 0.1 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 0.1 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.8 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 11.5 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.9 | 13.0 | GO:0030478 | actin cap(GO:0030478) |
| 0.7 | 2.0 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.5 | 1.4 | GO:0030849 | autosome(GO:0030849) |
| 0.4 | 2.7 | GO:1990357 | terminal web(GO:1990357) |
| 0.4 | 1.3 | GO:0060187 | cell pole(GO:0060187) |
| 0.4 | 5.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.4 | 1.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 1.5 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.4 | 1.8 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.3 | 1.0 | GO:1990617 | CHOP-ATF4 complex(GO:1990617) |
| 0.2 | 2.8 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.2 | 0.8 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.2 | 3.0 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 0.2 | 1.6 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 1.0 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 0.5 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.2 | 5.4 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.2 | 1.4 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.1 | 1.8 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.6 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.1 | 0.5 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.1 | 1.6 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.1 | 0.7 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.1 | 0.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.2 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 0.6 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 8.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 2.1 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 2.2 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 1.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 2.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.8 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 0.6 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.1 | 2.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.2 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.1 | 3.9 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 5.0 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.1 | 0.9 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 1.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 1.1 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.5 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.6 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 1.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.0 | 0.4 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.8 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 1.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 1.0 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 2.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 5.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 1.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 1.9 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 6.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 3.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 11.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 14.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.1 | GO:0033290 | eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207) |
| 0.0 | 0.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 2.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.0 | 0.4 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 1.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 3.5 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 0.2 | GO:0070449 | elongin complex(GO:0070449) |
| 0.0 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 4.4 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.5 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.0 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 3.1 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.6 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 1.0 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.7 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 1.6 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 0.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.2 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.1 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 2.6 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 1.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.0 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 1.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.2 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.0 | 0.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0005427 | proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) |
| 0.9 | 5.4 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.8 | 8.2 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.7 | 2.9 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.5 | 1.5 | GO:0035731 | S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731) |
| 0.5 | 4.5 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.4 | 2.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.4 | 13.0 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.4 | 1.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.4 | 1.1 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.4 | 1.1 | GO:0015489 | polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) |
| 0.3 | 2.0 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.3 | 1.9 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.3 | 5.7 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.3 | 1.9 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.2 | 1.7 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.2 | 1.5 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.2 | 0.9 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.2 | 3.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 1.8 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.2 | 0.7 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.2 | 0.6 | GO:0008903 | hydroxypyruvate isomerase activity(GO:0008903) |
| 0.2 | 0.8 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.2 | 0.6 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.2 | 0.7 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.2 | 1.0 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.2 | 0.5 | GO:0030617 | transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) |
| 0.1 | 0.6 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 0.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 25.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 1.4 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 5.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 0.4 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711) |
| 0.1 | 0.4 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 1.8 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 4.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 0.6 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.1 | 4.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.1 | 0.8 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.1 | 1.8 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.1 | 1.1 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 0.3 | GO:0031775 | lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039) |
| 0.1 | 1.0 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.5 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.1 | 0.3 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.1 | 0.6 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.1 | 0.6 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.1 | 0.5 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 11.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 0.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.1 | 3.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 1.8 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 1.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 1.8 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 1.0 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.1 | 0.4 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 0.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 1.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 6.9 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 2.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 2.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 1.0 | GO:0052834 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.1 | 1.5 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.6 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.1 | 4.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.3 | GO:0051800 | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800) |
| 0.1 | 0.5 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.1 | 0.5 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.3 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.1 | 0.2 | GO:0047225 | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225) |
| 0.1 | 0.4 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.1 | 0.4 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 0.9 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 1.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 1.0 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 0.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.5 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.6 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 0.1 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.0 | 0.6 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.5 | GO:0036122 | BMP binding(GO:0036122) |
| 0.0 | 1.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.8 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 0.1 | GO:0035375 | zymogen binding(GO:0035375) |
| 0.0 | 0.8 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 1.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.8 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 1.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 0.3 | GO:0102345 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 0.0 | 0.5 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 1.0 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 0.4 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 1.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.3 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.0 | 0.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.0 | 6.2 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 7.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.9 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 1.1 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 1.0 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.1 | GO:0048040 | UDP-glucuronate decarboxylase activity(GO:0048040) |
| 0.0 | 0.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 0.1 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.0 | 0.7 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 1.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.4 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.4 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.0 | 0.4 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 0.8 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.1 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.0 | 0.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.1 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.0 | 0.1 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.0 | 0.4 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.2 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 0.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.2 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.0 | 0.3 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.0 | 1.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.0 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.0 | 0.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 1.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.2 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.8 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.9 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.3 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.1 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.0 | 0.5 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.0 | GO:0015616 | DNA translocase activity(GO:0015616) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.2 | 10.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.2 | 5.8 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 6.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 0.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 6.3 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 2.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 5.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 1.0 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 0.8 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 0.6 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.6 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 3.1 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 2.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.4 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 9.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.2 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.0 | 2.6 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.1 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 1.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 2.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.9 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.6 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.8 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.6 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.5 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.3 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 0.3 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 2.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 3.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.3 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 17.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.3 | 4.1 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.2 | 5.2 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.2 | 8.8 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.2 | 0.9 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.2 | 6.8 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.2 | 4.4 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 1.1 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 0.5 | REACTOME BILE ACID AND BILE SALT METABOLISM | Genes involved in Bile acid and bile salt metabolism |
| 0.1 | 0.6 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.1 | 1.9 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 0.6 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 6.3 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.9 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.1 | 1.1 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 0.7 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 1.7 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 1.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 0.8 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.4 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 1.0 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.6 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.0 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 1.9 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 2.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 2.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.9 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 1.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.2 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.6 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.8 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.8 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.9 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 0.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 1.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 1.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.2 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.4 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.4 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.1 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 0.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 2.7 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.1 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.5 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |