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avrg: Illumina Body Map 2 (GSE30611)

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Results for HOXD1

Z-value: 0.97

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Transcription factors associated with HOXD1

Gene Symbol Gene ID Gene Info
HOXD1
ENSG00000128645.15 HOXD1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD1hg38_v1_chr2_+_176188658_1761886740.373.8e-02Click!

Activity profile of HOXD1 motif

Sorted Z-values of HOXD1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_26572254 3.82 ENST00000529533.6
MUC15
mucin 15, cell surface associated
chr11_-_26572102 3.25 ENST00000455601.6
MUC15
mucin 15, cell surface associated
chr11_-_26572130 3.04 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr8_+_91249307 2.94 ENST00000309536.6
ENST00000276609.8
SLC26A7
solute carrier family 26 member 7
chr11_+_72189659 1.98 ENST00000393681.6
FOLR1
folate receptor alpha
chr11_+_72189528 1.87 ENST00000312293.9
FOLR1
folate receptor alpha
chr17_-_7263959 1.38 ENST00000571932.2
CLDN7
claudin 7
chr5_-_97142579 1.37 ENST00000274382.9
LIX1
limb and CNS expressed 1
chr11_+_102047422 1.23 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
CFAP300
cilia and flagella associated protein 300
chr2_+_134838610 1.20 ENST00000356140.10
ENST00000392928.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr3_+_2892199 1.16 ENST00000397459.6
CNTN4
contactin 4
chr1_-_201171545 1.15 ENST00000367333.6
TMEM9
transmembrane protein 9
chr6_-_110179995 1.04 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr20_-_51802509 1.02 ENST00000371539.7
ENST00000217086.9
SALL4
spalt like transcription factor 4
chr13_+_77741160 0.94 ENST00000314070.9
ENST00000351546.7
SLAIN1
SLAIN motif family member 1
chrX_+_115593570 0.92 ENST00000539310.5
PLS3
plastin 3
chr12_-_23584600 0.91 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr11_+_65787056 0.83 ENST00000335987.8
OVOL1
ovo like transcriptional repressor 1
chr13_+_77741212 0.78 ENST00000441784.5
SLAIN1
SLAIN motif family member 1
chr15_+_62758585 0.76 ENST00000472902.1
TLN2
talin 2
chr15_+_21579912 0.75 ENST00000628444.1
LINC02203
long intergenic non-protein coding RNA 2203
chrX_+_108045050 0.74 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr7_-_73842508 0.71 ENST00000297873.9
METTL27
methyltransferase like 27
chr15_+_22015233 0.65 ENST00000639059.1
ENST00000640156.1
ENSG00000285472.1
ENSG00000284500.3
novel protein
novel transcript
chrX_+_108044967 0.62 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr7_+_134127299 0.61 ENST00000645682.1
ENST00000285928.2
LRGUK
leucine rich repeats and guanylate kinase domain containing
chr1_+_160400543 0.61 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr11_-_72112750 0.59 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
ANAPC15
anaphase promoting complex subunit 15
chr11_-_102780620 0.56 ENST00000279441.9
ENST00000539681.1
MMP10
matrix metallopeptidase 10
chr7_+_37683817 0.55 ENST00000476620.1
EPDR1
ependymin related 1
chr4_-_149815826 0.53 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr6_-_110179855 0.53 ENST00000368938.5
WASF1
WASP family member 1
chr5_+_177384430 0.51 ENST00000512593.5
ENST00000324417.6
SLC34A1
solute carrier family 34 member 1
chrX_+_54920796 0.51 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
TRO
trophinin
chr8_+_54616057 0.49 ENST00000637698.1
RP1
RP1 axonemal microtubule associated
chr20_+_9514562 0.47 ENST00000246070.3
LAMP5
lysosomal associated membrane protein family member 5
chr7_-_81770039 0.45 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr11_-_72112068 0.44 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
ANAPC15
anaphase promoting complex subunit 15
chr2_+_190356514 0.44 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr6_+_130421086 0.43 ENST00000545622.5
TMEM200A
transmembrane protein 200A
chr12_+_28257195 0.43 ENST00000381259.5
CCDC91
coiled-coil domain containing 91
chr2_+_186506713 0.42 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr11_-_72112669 0.41 ENST00000545944.5
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr8_-_48921419 0.41 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr9_+_121567057 0.41 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr12_+_15546344 0.40 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
PTPRO
protein tyrosine phosphatase receptor type O
chr1_-_111488795 0.39 ENST00000472933.2
TMIGD3
transmembrane and immunoglobulin domain containing 3
chr3_+_158801926 0.34 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
MFSD1
major facilitator superfamily domain containing 1
chr7_-_81770013 0.31 ENST00000465234.2
HGF
hepatocyte growth factor
chr4_+_85827745 0.31 ENST00000509300.5
ARHGAP24
Rho GTPase activating protein 24
chr3_-_151316795 0.30 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr7_-_100119840 0.28 ENST00000437822.6
TAF6
TATA-box binding protein associated factor 6
chr16_+_53099100 0.27 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr13_+_35476740 0.26 ENST00000537702.5
NBEA
neurobeachin
chr15_-_37101205 0.25 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
MEIS2
Meis homeobox 2
chr7_-_100119323 0.24 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TAF6
TATA-box binding protein associated factor 6
chr4_+_112647059 0.23 ENST00000511529.1
LARP7
La ribonucleoprotein 7, transcriptional regulator
chr5_-_97142753 0.23 ENST00000512378.1
LIX1
limb and CNS expressed 1
chr4_-_145180496 0.22 ENST00000447906.8
OTUD4
OTU deubiquitinase 4
chr11_-_95923763 0.22 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
MTMR2
myotubularin related protein 2
chr7_-_100119317 0.22 ENST00000440225.5
TAF6
TATA-box binding protein associated factor 6
chr4_+_85827891 0.22 ENST00000514229.5
ARHGAP24
Rho GTPase activating protein 24
chr15_+_58410543 0.22 ENST00000356113.10
ENST00000414170.7
LIPC
lipase C, hepatic type
chr19_+_54137740 0.21 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CNOT3
CCR4-NOT transcription complex subunit 3
chr10_+_27532521 0.21 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chr5_+_64505981 0.21 ENST00000334025.3
RGS7BP
regulator of G protein signaling 7 binding protein
chr7_+_6615576 0.20 ENST00000457543.4
ZNF853
zinc finger protein 853
chr10_+_97446194 0.18 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr1_-_224437028 0.17 ENST00000445239.1
WDR26
WD repeat domain 26
chr7_-_81770122 0.16 ENST00000423064.7
HGF
hepatocyte growth factor
chr5_-_20575850 0.15 ENST00000507958.5
CDH18
cadherin 18
chr11_-_95924067 0.13 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
MTMR2
myotubularin related protein 2
chr19_-_3557563 0.12 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr6_+_130018565 0.11 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr1_-_151459471 0.11 ENST00000271715.7
POGZ
pogo transposable element derived with ZNF domain
chr3_-_99850976 0.09 ENST00000487087.5
FILIP1L
filamin A interacting protein 1 like
chr10_+_97446137 0.09 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr12_+_64404338 0.08 ENST00000332707.10
XPOT
exportin for tRNA
chr20_-_51802433 0.08 ENST00000395997.3
SALL4
spalt like transcription factor 4
chr5_-_22853320 0.08 ENST00000504376.6
ENST00000382254.6
CDH12
cadherin 12
chr8_+_54616078 0.08 ENST00000220676.2
RP1
RP1 axonemal microtubule associated
chr1_-_151459198 0.08 ENST00000531094.5
POGZ
pogo transposable element derived with ZNF domain
chr15_-_55270874 0.08 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A
RAB27A, member RAS oncogene family
chr8_-_48921735 0.08 ENST00000396822.6
SNAI2
snail family transcriptional repressor 2
chr7_+_100119607 0.05 ENST00000262932.5
CNPY4
canopy FGF signaling regulator 4
chr22_+_24555981 0.05 ENST00000215829.8
ENST00000402849.5
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide
chr17_-_40799939 0.05 ENST00000306658.8
KRT28
keratin 28
chr18_+_36129444 0.04 ENST00000543127.5
ELP2
elongator acetyltransferase complex subunit 2
chr22_-_28094135 0.03 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr12_-_118359105 0.03 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr1_-_151459169 0.02 ENST00000368863.6
ENST00000409503.5
ENST00000491586.5
ENST00000533351.5
POGZ
pogo transposable element derived with ZNF domain
chr7_-_81769971 0.01 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.2 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.2 0.5 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.8 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 2.9 GO:0019532 oxalate transport(GO:0019532)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.6 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 10.1 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 3.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 10.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 9.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling