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avrg: Illumina Body Map 2 (GSE30611)

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Results for ISL1

Z-value: 1.58

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Transcription factors associated with ISL1

Gene Symbol Gene ID Gene Info
ISL1
ENSG00000016082.15 ISL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL1hg38_v1_chr5_+_51383394_51383454-0.067.6e-01Click!

Activity profile of ISL1 motif

Sorted Z-values of ISL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_94925759 4.11 ENST00000415017.1
ENST00000545882.5
CNN3
calponin 3
chr2_-_174846405 3.39 ENST00000409597.5
ENST00000413882.6
CHN1
chimerin 1
chr12_-_91180365 3.24 ENST00000547937.5
DCN
decorin
chr4_-_176002332 3.17 ENST00000280187.11
ENST00000512509.5
GPM6A
glycoprotein M6A
chrX_-_15664798 3.05 ENST00000380342.4
CLTRN
collectrin, amino acid transport regulator
chr9_+_131096476 2.77 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
AIF1L
allograft inflammatory factor 1 like
chr19_-_17377334 2.58 ENST00000252590.9
ENST00000599426.1
PLVAP
plasmalemma vesicle associated protein
chr4_-_86360039 2.57 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
MAPK10
mitogen-activated protein kinase 10
chr2_-_223602284 2.52 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
SCG2
secretogranin II
chr2_+_172860038 2.51 ENST00000538974.5
ENST00000540783.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr5_+_141370236 2.42 ENST00000576222.2
ENST00000618934.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr5_+_32710630 2.40 ENST00000326958.5
NPR3
natriuretic peptide receptor 3
chr12_-_6375556 2.37 ENST00000228916.7
SCNN1A
sodium channel epithelial 1 subunit alpha
chr6_-_130890393 2.31 ENST00000456097.6
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr4_+_168497044 2.20 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chr4_+_168497066 2.16 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr12_-_6375209 2.14 ENST00000360168.7
SCNN1A
sodium channel epithelial 1 subunit alpha
chr1_-_79006680 2.13 ENST00000370742.4
ENST00000656841.1
ADGRL4
adhesion G protein-coupled receptor L4
chr15_+_48206286 2.08 ENST00000396577.7
ENST00000380993.8
SLC12A1
solute carrier family 12 member 1
chr8_+_69492793 2.07 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
SULF1
sulfatase 1
chr2_+_95025700 2.02 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
MAL
mal, T cell differentiation protein
chrX_-_103686687 2.01 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
MORF4L2
mortality factor 4 like 2
chr1_+_81800368 1.93 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
ADGRL2
adhesion G protein-coupled receptor L2
chr8_+_91249307 1.90 ENST00000309536.6
ENST00000276609.8
SLC26A7
solute carrier family 26 member 7
chr4_-_76898118 1.86 ENST00000334306.4
SOWAHB
sosondowah ankyrin repeat domain family member B
chr9_-_92404559 1.85 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr4_-_185956348 1.84 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
SORBS2
sorbin and SH3 domain containing 2
chr1_+_196652022 1.80 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
CFH
complement factor H
chr1_-_79006773 1.80 ENST00000671209.1
ADGRL4
adhesion G protein-coupled receptor L4
chr19_-_12778412 1.72 ENST00000589400.5
ENST00000590839.5
ENST00000592079.5
HOOK2
hook microtubule tethering protein 2
chr9_+_27109135 1.71 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr12_+_57610150 1.70 ENST00000333972.11
ARHGEF25
Rho guanine nucleotide exchange factor 25
chr1_-_156248084 1.65 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
PAQR6
progestin and adipoQ receptor family member 6
chr3_-_138594129 1.62 ENST00000485115.1
ENST00000484888.5
ENST00000468900.5
ENST00000481834.5
ENST00000264982.8
CEP70
centrosomal protein 70
chr15_+_59611776 1.60 ENST00000396065.3
ENST00000560585.5
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_141397942 1.58 ENST00000617380.2
ENST00000621169.1
PCDHGB5
protocadherin gamma subfamily B, 5
chr12_+_79045680 1.56 ENST00000552624.5
SYT1
synaptotagmin 1
chr11_-_12009727 1.55 ENST00000525493.5
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr11_-_115256891 1.54 ENST00000545094.5
CADM1
cell adhesion molecule 1
chr15_+_80404320 1.50 ENST00000303329.9
ENST00000622346.4
ARNT2
aryl hydrocarbon receptor nuclear translocator 2
chrX_+_55452119 1.50 ENST00000342972.3
MAGEH1
MAGE family member H1
chr11_-_125481585 1.47 ENST00000577924.1
FEZ1
fasciculation and elongation protein zeta 1
chr1_+_192575765 1.39 ENST00000469578.2
ENST00000367459.8
RGS1
regulator of G protein signaling 1
chr12_-_49897056 1.35 ENST00000552863.5
FAIM2
Fas apoptotic inhibitory molecule 2
chr18_-_24397784 1.33 ENST00000399441.4
ENST00000319481.8
OSBPL1A
oxysterol binding protein like 1A
chr9_-_92404690 1.32 ENST00000447356.1
OGN
osteoglycin
chr5_+_32711313 1.32 ENST00000265074.13
NPR3
natriuretic peptide receptor 3
chr7_-_82005790 1.31 ENST00000443883.1
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr6_-_116254063 1.31 ENST00000420283.3
TSPYL4
TSPY like 4
chr3_-_192727500 1.31 ENST00000430714.5
ENST00000418610.1
ENST00000445105.7
ENST00000684728.1
ENST00000448795.5
ENST00000683935.1
ENST00000684282.1
ENST00000683451.1
FGF12
fibroblast growth factor 12
chr9_+_101185029 1.30 ENST00000395056.2
PLPPR1
phospholipid phosphatase related 1
chr5_+_174045673 1.30 ENST00000303177.8
ENST00000519867.5
NSG2
neuronal vesicle trafficking associated 2
chr9_+_27109200 1.29 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr3_-_100993507 1.28 ENST00000284322.10
ABI3BP
ABI family member 3 binding protein
chr21_-_32813695 1.27 ENST00000479548.2
ENST00000490358.5
C21orf62
chromosome 21 open reading frame 62
chr7_+_151114597 1.27 ENST00000335367.7
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr6_-_129710145 1.26 ENST00000368149.3
ARHGAP18
Rho GTPase activating protein 18
chr4_-_86360071 1.26 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
MAPK10
mitogen-activated protein kinase 10
chr2_+_172928165 1.26 ENST00000535187.5
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr2_-_189179754 1.22 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr12_+_119668109 1.22 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr7_-_108240049 1.20 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr18_-_50195138 1.20 ENST00000285039.12
MYO5B
myosin VB
chr8_+_35235467 1.19 ENST00000404895.7
UNC5D
unc-5 netrin receptor D
chr12_+_78864768 1.19 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr3_-_100993409 1.16 ENST00000471714.6
ABI3BP
ABI family member 3 binding protein
chr11_-_35360050 1.16 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr3_-_100993448 1.16 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI3BP
ABI family member 3 binding protein
chr1_+_99646025 1.15 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr11_-_63015831 1.15 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr1_-_204166334 1.12 ENST00000272190.9
REN
renin
chr6_+_150683593 1.12 ENST00000644968.1
PLEKHG1
pleckstrin homology and RhoGEF domain containing G1
chr1_-_113887574 1.11 ENST00000393316.8
BCL2L15
BCL2 like 15
chr15_+_65530418 1.11 ENST00000562901.5
ENST00000261875.10
ENST00000442729.6
ENST00000565299.5
ENST00000568793.5
HACD3
3-hydroxyacyl-CoA dehydratase 3
chr11_+_57805541 1.11 ENST00000683201.1
ENST00000683769.1
CTNND1
catenin delta 1
chr5_+_137867852 1.07 ENST00000421631.6
ENST00000239926.9
MYOT
myotilin
chr9_-_110999458 1.07 ENST00000374430.6
LPAR1
lysophosphatidic acid receptor 1
chr4_-_185956652 1.06 ENST00000355634.9
SORBS2
sorbin and SH3 domain containing 2
chr11_-_63015804 1.01 ENST00000535878.5
ENST00000545207.5
SLC22A8
solute carrier family 22 member 8
chr2_-_174847015 0.97 ENST00000650938.1
CHN1
chimerin 1
chr13_-_99016034 0.97 ENST00000448493.7
DOCK9
dedicator of cytokinesis 9
chr1_+_103617427 0.95 ENST00000423678.2
ENST00000414303.7
AMY2A
amylase alpha 2A
chr9_+_133459965 0.94 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
CACFD1
calcium channel flower domain containing 1
chr8_+_22053543 0.90 ENST00000519850.5
ENST00000381470.7
DMTN
dematin actin binding protein
chr19_-_49640092 0.89 ENST00000246792.4
RRAS
RAS related
chr2_-_174847250 0.89 ENST00000409089.7
CHN1
chimerin 1
chr3_+_35679614 0.89 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
ARPP21
cAMP regulated phosphoprotein 21
chr1_-_156248038 0.88 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
PAQR6
progestin and adipoQ receptor family member 6
chr2_-_54987578 0.88 ENST00000486085.5
RTN4
reticulon 4
chr12_+_78863962 0.88 ENST00000393240.7
SYT1
synaptotagmin 1
chr18_+_616711 0.88 ENST00000579494.1
CLUL1
clusterin like 1
chr10_+_122163672 0.87 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr1_+_81699665 0.86 ENST00000359929.7
ADGRL2
adhesion G protein-coupled receptor L2
chr4_+_70195719 0.85 ENST00000683306.1
ODAM
odontogenic, ameloblast associated
chr5_+_73813518 0.85 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr5_-_41794211 0.84 ENST00000512084.5
OXCT1
3-oxoacid CoA-transferase 1
chr11_-_107858777 0.82 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr3_+_159069252 0.81 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr6_-_136466858 0.80 ENST00000544465.5
MAP7
microtubule associated protein 7
chr18_+_74499861 0.80 ENST00000324301.12
CNDP2
carnosine dipeptidase 2
chr1_-_156248013 0.80 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6
chrX_+_51893533 0.77 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGED1
MAGE family member D1
chr10_-_60572599 0.77 ENST00000503366.5
ANK3
ankyrin 3
chr5_-_88884525 0.76 ENST00000502983.5
MEF2C
myocyte enhancer factor 2C
chr6_+_27388748 0.76 ENST00000244576.9
ZNF391
zinc finger protein 391
chr8_-_12194067 0.76 ENST00000524571.6
ENST00000533852.6
ENST00000533513.1
ENST00000448228.6
ENST00000534520.5
FAM86B1
family with sequence similarity 86 member B1
chr18_+_616672 0.76 ENST00000338387.11
CLUL1
clusterin like 1
chrX_-_23907887 0.75 ENST00000379226.9
APOO
apolipoprotein O
chr21_-_32813679 0.74 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr4_+_61201223 0.73 ENST00000512091.6
ADGRL3
adhesion G protein-coupled receptor L3
chr5_+_134846065 0.73 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
C5orf24
chromosome 5 open reading frame 24
chr5_+_137867868 0.73 ENST00000515645.1
MYOT
myotilin
chr10_-_77637789 0.73 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr6_-_52763473 0.72 ENST00000493422.3
GSTA2
glutathione S-transferase alpha 2
chr9_-_101435760 0.72 ENST00000647789.2
ENST00000616752.1
ALDOB
aldolase, fructose-bisphosphate B
chr5_+_141213919 0.72 ENST00000341948.6
PCDHB13
protocadherin beta 13
chr12_-_86838867 0.71 ENST00000621808.4
MGAT4C
MGAT4 family member C
chrX_+_66162663 0.70 ENST00000519389.6
HEPH
hephaestin
chr7_+_90709530 0.70 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr18_+_48539112 0.70 ENST00000382998.8
CTIF
cap binding complex dependent translation initiation factor
chr6_+_31547560 0.69 ENST00000376148.9
ENST00000376145.8
NFKBIL1
NFKB inhibitor like 1
chrX_+_136197039 0.69 ENST00000370683.6
FHL1
four and a half LIM domains 1
chr4_+_113049479 0.68 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ANK2
ankyrin 2
chr11_-_107858561 0.68 ENST00000375682.8
SLC35F2
solute carrier family 35 member F2
chr11_-_70717994 0.67 ENST00000659264.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_-_132625378 0.67 ENST00000522789.5
LRRC6
leucine rich repeat containing 6
chr1_-_160285120 0.66 ENST00000368072.10
PEX19
peroxisomal biogenesis factor 19
chr9_-_14300231 0.66 ENST00000636735.1
NFIB
nuclear factor I B
chr6_+_167291329 0.66 ENST00000366829.2
UNC93A
unc-93 homolog A
chr4_-_86360010 0.66 ENST00000641911.1
ENST00000641072.1
ENST00000359221.8
ENST00000640490.1
MAPK10
mitogen-activated protein kinase 10
chr5_-_138875290 0.66 ENST00000521094.2
ENST00000274711.7
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr12_-_10098977 0.65 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chrX_+_21940693 0.65 ENST00000404933.7
ENST00000379404.5
SMS
spermine synthase
chr4_+_87832917 0.65 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr6_+_89562766 0.64 ENST00000485637.5
ENST00000522705.5
ANKRD6
ankyrin repeat domain 6
chr6_+_168017873 0.64 ENST00000351261.4
ENST00000354419.6
KIF25
kinesin family member 25
chr7_+_90709231 0.63 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr10_-_77637721 0.61 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr12_-_27971970 0.61 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr7_+_80199266 0.61 ENST00000647672.1
GNAI1
G protein subunit alpha i1
chr9_-_109119915 0.60 ENST00000374586.8
TMEM245
transmembrane protein 245
chr18_-_5544250 0.60 ENST00000540638.6
ENST00000342933.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr8_-_19682576 0.59 ENST00000332246.10
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr18_+_48539017 0.59 ENST00000256413.8
CTIF
cap binding complex dependent translation initiation factor
chr6_+_89562308 0.59 ENST00000522441.5
ANKRD6
ankyrin repeat domain 6
chr22_+_39994926 0.58 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr12_-_121016345 0.58 ENST00000535367.1
ENST00000538296.5
ENST00000288757.7
ENST00000539736.5
ENST00000537817.5
C12orf43
chromosome 12 open reading frame 43
chr7_-_78771265 0.58 ENST00000630991.2
ENST00000629359.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_140841183 0.57 ENST00000378123.4
ENST00000531613.2
PCDHA8
protocadherin alpha 8
chr15_+_42359454 0.56 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
CAPN3
calpain 3
chr4_-_103077282 0.56 ENST00000503230.5
ENST00000503818.1
SLC9B2
solute carrier family 9 member B2
chr12_-_42484298 0.56 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
PRICKLE1
prickle planar cell polarity protein 1
chr6_+_167291309 0.56 ENST00000230256.8
UNC93A
unc-93 homolog A
chr2_+_241350087 0.56 ENST00000451310.1
SEPTIN2
septin 2
chr8_+_38728186 0.56 ENST00000519416.5
ENST00000520615.5
TACC1
transforming acidic coiled-coil containing protein 1
chr6_-_138499487 0.54 ENST00000343505.9
NHSL1
NHS like 1
chr5_+_175861628 0.52 ENST00000509837.5
CPLX2
complexin 2
chr18_-_5543960 0.51 ENST00000400111.8
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr10_-_93482326 0.51 ENST00000359263.9
MYOF
myoferlin
chr6_+_36885944 0.51 ENST00000480824.7
C6orf89
chromosome 6 open reading frame 89
chr5_+_140875299 0.50 ENST00000613593.1
ENST00000398631.3
PCDHA12
protocadherin alpha 12
chr4_+_56436233 0.49 ENST00000512576.3
PAICS
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr9_-_179008 0.49 ENST00000613508.4
ENST00000382447.8
ENST00000382389.5
ENST00000377447.7
ENST00000382393.2
ENST00000314367.14
ENST00000356521.8
ENST00000377400.8
CBWD1
COBW domain containing 1
chr14_+_61697622 0.48 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr8_-_100559702 0.47 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ANKRD46
ankyrin repeat domain 46
chr22_-_32255344 0.47 ENST00000266086.6
SLC5A4
solute carrier family 5 member 4
chr10_-_93482194 0.46 ENST00000358334.9
ENST00000371488.3
MYOF
myoferlin
chr11_-_26723361 0.46 ENST00000533617.5
SLC5A12
solute carrier family 5 member 12
chr19_-_18606779 0.46 ENST00000684169.1
ENST00000392386.8
CRLF1
cytokine receptor like factor 1
chr8_+_26390362 0.46 ENST00000518611.5
BNIP3L
BCL2 interacting protein 3 like
chr8_+_30638562 0.46 ENST00000517349.2
SMIM18
small integral membrane protein 18
chr3_-_157503339 0.45 ENST00000392833.6
VEPH1
ventricular zone expressed PH domain containing 1
chr3_-_157503375 0.45 ENST00000362010.7
VEPH1
ventricular zone expressed PH domain containing 1
chr2_+_176157293 0.44 ENST00000683222.1
HOXD3
homeobox D3
chr18_-_5543988 0.44 ENST00000341928.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr12_-_10098940 0.44 ENST00000420265.2
CLEC1A
C-type lectin domain family 1 member A
chr5_+_140868945 0.44 ENST00000398640.7
PCDHA11
protocadherin alpha 11
chr10_-_73358853 0.43 ENST00000355577.8
ENST00000310715.7
CFAP70
cilia and flagella associated protein 70
chr1_+_171248471 0.42 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
FMO1
flavin containing dimethylaniline monoxygenase 1
chr1_-_154870264 0.42 ENST00000618040.4
ENST00000271915.9
KCNN3
potassium calcium-activated channel subfamily N member 3
chrX_-_117973717 0.42 ENST00000262820.7
KLHL13
kelch like family member 13
chr5_-_138875362 0.41 ENST00000518785.1
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr12_+_55572468 0.40 ENST00000641114.1
OR2AP1
olfactory receptor family 2 subfamily AP member 1
chr17_+_59683869 0.40 ENST00000472651.5
CLTC
clathrin heavy chain
chr7_-_13986498 0.40 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETV1
ETS variant transcription factor 1
chrX_-_119852948 0.40 ENST00000276201.7
ENST00000345865.6
UPF3B
UPF3B regulator of nonsense mediated mRNA decay
chr6_-_52840843 0.39 ENST00000370989.6
GSTA5
glutathione S-transferase alpha 5
chr8_-_3409528 0.39 ENST00000335551.11
CSMD1
CUB and Sushi multiple domains 1
chr1_-_197201262 0.38 ENST00000367405.5
ZBTB41
zinc finger and BTB domain containing 41
chr12_-_30735014 0.38 ENST00000433722.6
CAPRIN2
caprin family member 2
chr1_-_160098593 0.38 ENST00000314485.12
IGSF8
immunoglobulin superfamily member 8
chr16_-_30787169 0.37 ENST00000262525.6
ZNF629
zinc finger protein 629
chr6_+_46793379 0.36 ENST00000230588.9
ENST00000611727.2
MEP1A
meprin A subunit alpha
chr17_+_35587239 0.36 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
AP2B1
adaptor related protein complex 2 subunit beta 1
chr18_-_55510753 0.36 ENST00000543082.5
TCF4
transcription factor 4
chr20_+_19889502 0.35 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr3_+_4303602 0.35 ENST00000358950.4
SETMAR
SET domain and mariner transposase fusion gene
chr2_-_219170023 0.34 ENST00000409878.8
ENST00000455516.6
ENST00000295738.11
SLC23A3
solute carrier family 23 member 3
chr9_+_110090197 0.34 ENST00000480388.1
PALM2AKAP2
PALM2 and AKAP2 fusion
chr15_+_42359577 0.34 ENST00000357568.8
CAPN3
calpain 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 1.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 2.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 3.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 4.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 1.6 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.2 0.6 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.2 1.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 4.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 3.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 1.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.2 GO:0032439 endosome localization(GO:0032439)
0.2 3.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 2.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.6 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 3.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 2.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 3.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.9 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 2.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.8 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 5.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.3 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.9 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 2.6 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.2 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.1 0.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.8 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.2 GO:0035878 nail development(GO:0035878)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 2.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 3.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.7 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 3.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:0060083 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 1.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 3.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) immunoglobulin V(D)J recombination(GO:0033152) T cell receptor V(D)J recombination(GO:0033153) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 6.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.7 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.7 GO:0070695 FHF complex(GO:0070695)
0.2 1.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 4.9 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 2.5 GO:0031045 dense core granule(GO:0031045)
0.1 2.3 GO:0008091 spectrin(GO:0008091)
0.1 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 3.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 1.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.0 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 3.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.9 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 4.3 GO:0005901 caveola(GO:0005901)
0.0 1.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 4.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 3.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 4.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 4.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0099738 cell cortex region(GO:0099738)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.6 3.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 2.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.5 1.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.4 1.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.4 3.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 4.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 4.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.8 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.6 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 0.7 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.2 2.3 GO:0042731 PH domain binding(GO:0042731)
0.2 0.5 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2 1.1 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.8 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 5.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 3.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.3 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 6.8 GO:0005518 collagen binding(GO:0005518)
0.0 2.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.9 GO:0031432 titin binding(GO:0031432)
0.0 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 3.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 3.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.5 GO:0005496 steroid binding(GO:0005496)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.6 GO:0008083 growth factor activity(GO:0008083)
0.0 2.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 6.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 3.6 PID SHP2 PATHWAY SHP2 signaling
0.0 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 3.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 2.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 3.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 3.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 5.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 5.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis