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avrg: Illumina Body Map 2 (GSE30611)
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Results for KLF6
Z-value: 1.56
Motif logo
Transcription factors associated with KLF6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
KLF6
|
ENSG00000067082.15 | KLF6 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF6 | hg38_v1_chr10_-_3785197_3785216 | 0.36 | 4.0e-02 | Click! |
Activity profile of KLF6 motif
Sorted Z-values of KLF6 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 8.7 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.9 | 2.8 | GO:0061027 | umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) |
| 0.8 | 3.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.7 | 2.0 | GO:0061033 | semicircular canal formation(GO:0060876) secretion by lung epithelial cell involved in lung growth(GO:0061033) |
| 0.6 | 1.9 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 0.6 | 3.7 | GO:0009996 | negative regulation of cell fate specification(GO:0009996) |
| 0.6 | 1.7 | GO:0035508 | positive regulation of myosin-light-chain-phosphatase activity(GO:0035508) |
| 0.5 | 1.5 | GO:1902811 | tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037) |
| 0.5 | 2.0 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 0.5 | 2.0 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.5 | 1.5 | GO:1903597 | negative regulation of gap junction assembly(GO:1903597) |
| 0.5 | 1.5 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 0.5 | 1.9 | GO:0035625 | negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.5 | 1.4 | GO:2000656 | regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657) |
| 0.5 | 1.8 | GO:1905064 | negative regulation of vascular smooth muscle cell differentiation(GO:1905064) |
| 0.4 | 1.7 | GO:0001868 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.4 | 1.7 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 0.4 | 1.2 | GO:0032771 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 0.4 | 1.8 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.3 | 1.0 | GO:1902688 | fermentation(GO:0006113) regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) |
| 0.3 | 1.3 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.3 | 1.0 | GO:0003050 | regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050) |
| 0.3 | 2.5 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.3 | 0.9 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 0.3 | 3.3 | GO:0038033 | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) |
| 0.3 | 1.1 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.3 | 0.8 | GO:0034970 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970) |
| 0.3 | 2.5 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.3 | 1.1 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.3 | 0.3 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.3 | 1.1 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.3 | 2.1 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.3 | 0.5 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 0.3 | 1.0 | GO:0035910 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.3 | 1.3 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.3 | 0.3 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
| 0.3 | 1.0 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.2 | 3.0 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 0.2 | 0.7 | GO:0100057 | regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828) |
| 0.2 | 0.2 | GO:1904782 | negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) |
| 0.2 | 2.7 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.2 | 1.9 | GO:0071484 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.2 | 1.9 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.2 | 1.2 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.2 | 0.9 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.2 | 0.5 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.2 | 0.7 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.2 | 1.1 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.2 | 1.3 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.2 | 0.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.2 | 0.4 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.2 | 0.8 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.2 | 1.8 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 3.7 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.2 | 1.0 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.2 | 1.2 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.2 | 1.0 | GO:0046671 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.2 | 1.0 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.2 | 1.3 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.2 | 1.1 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.2 | 0.5 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.2 | 0.5 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.2 | 1.4 | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway(GO:0070120) |
| 0.2 | 0.7 | GO:0048372 | regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) |
| 0.2 | 0.2 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 0.2 | 2.4 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.2 | 2.2 | GO:0036309 | protein localization to M-band(GO:0036309) |
| 0.2 | 1.7 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.2 | 0.3 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.2 | 5.4 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.2 | 0.2 | GO:0097102 | negative regulation of auditory receptor cell differentiation(GO:0045608) endothelial tip cell fate specification(GO:0097102) |
| 0.2 | 1.1 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.1 | 0.9 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.7 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) |
| 0.1 | 0.7 | GO:0007571 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.1 | 2.1 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 3.6 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 0.7 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.7 | GO:1902460 | mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.1 | 0.8 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.1 | 0.4 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 0.1 | 0.7 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.1 | 0.4 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 1.9 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.1 | 0.5 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.1 | 0.3 | GO:0007402 | ganglion mother cell fate determination(GO:0007402) |
| 0.1 | 1.6 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 2.5 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.1 | 0.6 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
| 0.1 | 0.7 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.1 | 0.7 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.1 | 0.5 | GO:1904693 | midbrain morphogenesis(GO:1904693) |
| 0.1 | 0.4 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.1 | 0.9 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.4 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.1 | 0.9 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.1 | 0.1 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.1 | 0.5 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.1 | 0.7 | GO:0030421 | defecation(GO:0030421) |
| 0.1 | 2.7 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 1.2 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.1 | 0.6 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 0.1 | 1.4 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.1 | 0.7 | GO:0090116 | C-5 methylation of cytosine(GO:0090116) |
| 0.1 | 1.0 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.1 | 1.2 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.1 | 0.7 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 0.1 | 0.8 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 0.2 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 0.1 | 0.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 1.2 | GO:1904261 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 0.1 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.1 | 1.7 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.7 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.1 | 0.2 | GO:1902263 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 0.1 | 0.1 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.1 | 0.5 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 0.8 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.1 | 3.2 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.1 | GO:1902534 | single-organism membrane invagination(GO:1902534) |
| 0.1 | 0.6 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 1.0 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.1 | 0.3 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 0.5 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 0.2 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 0.1 | 0.3 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 0.3 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.1 | 0.2 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.1 | 0.2 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.1 | 3.9 | GO:0042092 | type 2 immune response(GO:0042092) |
| 0.1 | 0.4 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.1 | 0.9 | GO:0010452 | histone H3-K36 methylation(GO:0010452) |
| 0.1 | 0.3 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.1 | 0.3 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.1 | 0.4 | GO:0007549 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 0.4 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
| 0.1 | 0.9 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.1 | 1.0 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 1.1 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.0 | 0.2 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.0 | 0.4 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.0 | 0.6 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.0 | 2.3 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 1.1 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.0 | 0.4 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
| 0.0 | 1.9 | GO:0042749 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.0 | 1.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.3 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
| 0.0 | 0.3 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.0 | 1.6 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 0.1 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.0 | 1.5 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.0 | 0.4 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.0 | 0.9 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 1.0 | GO:0001946 | lymphangiogenesis(GO:0001946) |
| 0.0 | 0.7 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.0 | 0.3 | GO:0050893 | sensory processing(GO:0050893) |
| 0.0 | 2.2 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.1 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 0.4 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.0 | 0.4 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.0 | 0.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 1.7 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.2 | GO:0071681 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.0 | 0.6 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.0 | 0.3 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
| 0.0 | 0.6 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.0 | 1.6 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.4 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.0 | 0.4 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.3 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.0 | 0.1 | GO:0031445 | regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453) |
| 0.0 | 0.2 | GO:0010609 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) |
| 0.0 | 1.1 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.0 | 0.2 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.0 | 0.2 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.0 | 2.4 | GO:0006007 | glucose catabolic process(GO:0006007) |
| 0.0 | 0.4 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.0 | 0.2 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.0 | 0.2 | GO:1901090 | regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094) |
| 0.0 | 0.3 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.2 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.0 | 0.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.0 | 0.1 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.0 | 0.2 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.0 | 0.2 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.0 | 1.2 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.5 | GO:0070828 | heterochromatin organization(GO:0070828) |
| 0.0 | 0.9 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.0 | 0.2 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.0 | 0.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.0 | 0.4 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.6 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.5 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.1 | GO:0048560 | establishment of anatomical structure orientation(GO:0048560) establishment of organ orientation(GO:0048561) |
| 0.0 | 0.7 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.0 | 0.3 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
| 0.0 | 0.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.2 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016) |
| 0.0 | 0.1 | GO:0038109 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.0 | 0.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.5 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 0.3 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.0 | 1.3 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
| 0.0 | 0.4 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 1.0 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.4 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 2.7 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 2.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 0.2 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.0 | 0.1 | GO:1901910 | diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.0 | 0.7 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.4 | GO:0045003 | DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
| 0.0 | 0.1 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 0.0 | 0.9 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.5 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.4 | GO:0042249 | establishment of planar polarity of embryonic epithelium(GO:0042249) |
| 0.0 | 0.5 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.0 | 0.2 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.0 | 0.4 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.0 | 0.3 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.0 | 0.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.3 | GO:1904293 | negative regulation of ERAD pathway(GO:1904293) |
| 0.0 | 0.4 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.0 | 0.3 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 2.2 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.0 | 0.7 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 1.8 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
| 0.0 | 0.2 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.3 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.0 | 0.1 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.0 | 0.2 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 0.1 | GO:0010159 | specification of organ position(GO:0010159) |
| 0.0 | 0.2 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.0 | 0.2 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.0 | 0.5 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.0 | 0.5 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 0.4 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.2 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 0.3 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.0 | 0.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.1 | GO:1902966 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.0 | 0.1 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.0 | 0.2 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.0 | 0.2 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 0.0 | 0.3 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.1 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.0 | 0.1 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.0 | 0.4 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.0 | 0.2 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.0 | 0.4 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.6 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 0.3 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
| 0.0 | 0.1 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 0.0 | 0.9 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.0 | 0.3 | GO:0021511 | spinal cord patterning(GO:0021511) |
| 0.0 | 0.1 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.0 | 0.5 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.8 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.3 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 0.1 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.0 | 0.1 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 0.0 | 0.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 0.3 | GO:0031114 | negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
| 0.0 | 0.2 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 5.0 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.6 | 1.8 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
| 0.5 | 9.1 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.4 | 1.1 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.3 | 5.7 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 1.4 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.3 | 0.8 | GO:0060987 | lipid tube(GO:0060987) |
| 0.3 | 1.3 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.2 | 1.8 | GO:0032021 | NELF complex(GO:0032021) |
| 0.2 | 0.7 | GO:0055087 | Ski complex(GO:0055087) |
| 0.2 | 1.3 | GO:0032449 | CBM complex(GO:0032449) |
| 0.2 | 2.3 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 0.9 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.2 | 2.1 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.2 | 2.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 2.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 1.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 1.5 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 0.4 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 0.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 0.6 | GO:0036398 | TCR signalosome(GO:0036398) |
| 0.1 | 2.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 0.4 | GO:0032798 | Swi5-Sfr1 complex(GO:0032798) |
| 0.1 | 0.3 | GO:0000805 | X chromosome(GO:0000805) autosome(GO:0030849) |
| 0.1 | 0.9 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 0.3 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.1 | 2.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 0.9 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 3.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 1.7 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 2.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.2 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 1.3 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 0.7 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 1.2 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.9 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 2.1 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 1.0 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 1.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.0 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.2 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.4 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.0 | 1.1 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 1.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 4.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.1 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 2.2 | GO:0008305 | integrin complex(GO:0008305) |
| 0.0 | 0.6 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 5.7 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.7 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.0 | 0.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 1.7 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.9 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 3.4 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.0 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 2.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.1 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.3 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.5 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 0.4 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.3 | GO:0097413 | Lewy body(GO:0097413) |
| 0.0 | 0.3 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.1 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 0.1 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.1 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.3 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 7.5 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.5 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.4 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 8.7 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.7 | 2.8 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.6 | 1.9 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 0.6 | 3.0 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.5 | 1.9 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.4 | 1.3 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 0.4 | 2.5 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.4 | 2.0 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.4 | 1.1 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.3 | 1.4 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.3 | 1.7 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.3 | 1.0 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.3 | 1.5 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.3 | 1.8 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.3 | 3.6 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.3 | 3.8 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.3 | 1.1 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.3 | 0.8 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.2 | 1.5 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.2 | 1.4 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.2 | 2.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 0.9 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 0.2 | 1.2 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.2 | 0.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.2 | 1.1 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.2 | 1.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 0.6 | GO:0000035 | acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177) |
| 0.1 | 0.7 | GO:0086020 | gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) |
| 0.1 | 1.3 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 1.8 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 0.8 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 2.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.1 | 1.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 0.7 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.4 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 1.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.7 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 1.2 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 1.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.8 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.1 | 0.5 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.1 | 0.6 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 1.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.4 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 0.3 | GO:0005139 | interleukin-7 receptor binding(GO:0005139) |
| 0.1 | 0.6 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.4 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.1 | 0.3 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.1 | 0.4 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.1 | 0.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.7 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.1 | 1.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 2.2 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.7 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 3.0 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.2 | GO:0070362 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 0.1 | 1.6 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 3.7 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 1.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 1.6 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.1 | 1.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.9 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 2.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 1.9 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.1 | 2.8 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 0.3 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 0.3 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.1 | 0.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 0.5 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.1 | 1.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 2.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 1.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 0.4 | GO:0005047 | signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.2 | GO:0047291 | neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291) |
| 0.0 | 0.8 | GO:0010857 | calcium-dependent protein kinase activity(GO:0010857) |
| 0.0 | 0.1 | GO:1990698 | palmitoleoyltransferase activity(GO:1990698) |
| 0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 0.4 | GO:0016403 | dimethylargininase activity(GO:0016403) |
| 0.0 | 0.3 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.0 | 0.2 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 4.4 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.4 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 2.2 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 2.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.7 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 1.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.4 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 1.8 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.2 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.0 | 0.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.0 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.0 | 0.2 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.0 | 1.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 1.7 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 0.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 1.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 2.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.5 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.3 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 0.4 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.2 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.3 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.0 | 0.1 | GO:0052840 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.0 | 0.4 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.0 | 0.2 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.6 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.7 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 2.2 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.1 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.4 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.9 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 1.3 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.8 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.2 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.2 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.0 | 0.1 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.3 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 3.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 6.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 1.6 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.4 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 3.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 4.0 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.1 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.1 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.0 | 0.0 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.1 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.0 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 5.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.6 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 6.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 1.5 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 3.9 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.1 | 5.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.0 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 2.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 1.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 2.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 3.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 1.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.5 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 2.1 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 1.0 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.0 | 0.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 2.4 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 2.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 3.0 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 3.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 2.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 7.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.9 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.7 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 2.6 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.3 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.6 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.3 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 1.5 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.7 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 0.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.6 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 0.7 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.4 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 0.3 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 1.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.4 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.2 | 7.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 1.5 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 2.3 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 1.2 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 3.8 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 0.7 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 2.3 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 2.1 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 5.7 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.5 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 0.4 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 1.0 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.1 | 1.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 1.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.2 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 1.2 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.1 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.0 | 2.1 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 1.3 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 1.8 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 2.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.6 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.1 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.8 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 2.6 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 1.1 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 2.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 1.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.6 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.5 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.0 | 1.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.9 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 0.2 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.0 | 1.1 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.2 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 0.7 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 2.4 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.4 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 2.4 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 2.4 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.5 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.0 | 1.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.7 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |
| 0.0 | 0.4 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 0.2 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 0.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.5 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.3 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.4 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |