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avrg: Illumina Body Map 2 (GSE30611)

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Results for LHX3

Z-value: 1.22

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
LHX3
ENSG00000107187.17 LHX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3hg38_v1_chr9_-_136205122_136205133-0.232.2e-01Click!

Activity profile of LHX3 motif

Sorted Z-values of LHX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_48191648 3.45 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
SLC12A1
CTXN2
solute carrier family 12 member 1
cortexin 2
chr4_+_154563003 2.65 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr12_-_10130143 2.46 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
CLEC7A
C-type lectin domain containing 7A
chr3_+_151873634 2.17 ENST00000362032.6
SUCNR1
succinate receptor 1
chr12_-_10130241 2.00 ENST00000353231.9
ENST00000525605.1
CLEC7A
C-type lectin domain containing 7A
chr5_-_39274515 1.92 ENST00000510188.1
FYB1
FYN binding protein 1
chr19_-_51417791 1.84 ENST00000353836.9
SIGLEC10
sialic acid binding Ig like lectin 10
chr19_-_51417700 1.82 ENST00000529627.1
ENST00000439889.6
SIGLEC10
sialic acid binding Ig like lectin 10
chr18_+_74534493 1.82 ENST00000358821.8
CNDP1
carnosine dipeptidase 1
chr7_-_87713287 1.79 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ABCB1
ATP binding cassette subfamily B member 1
chr2_+_134838610 1.72 ENST00000356140.10
ENST00000392928.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_+_40310431 1.71 ENST00000681696.1
LRRK2
leucine rich repeat kinase 2
chr18_+_74534594 1.69 ENST00000582365.1
CNDP1
carnosine dipeptidase 1
chr5_-_88824266 1.52 ENST00000509373.1
ENST00000636541.1
MEF2C
myocyte enhancer factor 2C
chr12_-_10130082 1.51 ENST00000533022.5
CLEC7A
C-type lectin domain containing 7A
chr2_+_218129277 1.49 ENST00000428565.1
CXCR2
C-X-C motif chemokine receptor 2
chr4_+_157221598 1.45 ENST00000505888.1
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
chr7_-_36724457 1.44 ENST00000617537.5
ENST00000435386.1
AOAH
acyloxyacyl hydrolase
chr3_+_68006224 1.43 ENST00000496687.1
TAFA1
TAFA chemokine like family member 1
chr6_+_122996227 1.38 ENST00000275162.10
CLVS2
clavesin 2
chr8_-_109974688 1.32 ENST00000297404.1
KCNV1
potassium voltage-gated channel modifier subfamily V member 1
chr7_-_36724543 1.30 ENST00000612871.4
AOAH
acyloxyacyl hydrolase
chr1_-_150971935 1.16 ENST00000368949.8
CERS2
ceramide synthase 2
chr17_+_70075317 1.12 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr9_-_6605338 1.07 ENST00000638654.1
GLDC
glycine decarboxylase
chr1_-_150235972 1.06 ENST00000534220.1
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr18_-_3845321 1.04 ENST00000539435.5
ENST00000400147.6
DLGAP1
DLG associated protein 1
chr1_-_150236064 1.04 ENST00000532744.2
ENST00000369114.9
ENST00000369115.3
ENST00000583931.6
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr3_+_186974957 1.00 ENST00000438590.5
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr1_-_160579439 1.00 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84
CD84 molecule
chr4_+_157220691 0.99 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
chr16_-_28623560 0.99 ENST00000350842.8
SULT1A1
sulfotransferase family 1A member 1
chr2_+_184598520 0.97 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chr1_-_150235995 0.96 ENST00000436748.6
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr1_+_66354375 0.92 ENST00000480109.2
PDE4B
phosphodiesterase 4B
chr2_-_2324323 0.90 ENST00000648339.1
ENST00000647694.1
MYT1L
myelin transcription factor 1 like
chr13_-_83882456 0.89 ENST00000674365.1
SLITRK1
SLIT and NTRK like family member 1
chr5_+_127649018 0.86 ENST00000379445.7
CTXN3
cortexin 3
chr1_+_240245260 0.85 ENST00000441342.1
FMN2
formin 2
chr19_+_14583076 0.82 ENST00000547437.5
ENST00000417570.6
CLEC17A
C-type lectin domain containing 17A
chr4_-_23890070 0.80 ENST00000617484.4
ENST00000612355.1
PPARGC1A
PPARG coactivator 1 alpha
chr12_+_118981531 0.80 ENST00000267260.5
SRRM4
serine/arginine repetitive matrix 4
chr6_-_159045104 0.79 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr11_-_790062 0.79 ENST00000330106.5
CEND1
cell cycle exit and neuronal differentiation 1
chr12_-_7503841 0.78 ENST00000359156.8
CD163
CD163 molecule
chr7_+_30145789 0.78 ENST00000324489.5
MTURN
maturin, neural progenitor differentiation regulator homolog
chr18_+_57352541 0.77 ENST00000324000.4
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr12_-_7503744 0.76 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr13_-_83882390 0.75 ENST00000377084.3
SLITRK1
SLIT and NTRK like family member 1
chr7_-_123199960 0.75 ENST00000194130.7
SLC13A1
solute carrier family 13 member 1
chr5_-_88824334 0.75 ENST00000506716.5
MEF2C
myocyte enhancer factor 2C
chr10_-_72523936 0.75 ENST00000398763.8
ENST00000418483.6
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr1_-_150235943 0.74 ENST00000533654.5
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr2_-_144521042 0.73 ENST00000637267.2
ZEB2
zinc finger E-box binding homeobox 2
chr18_-_3845292 0.73 ENST00000400145.6
DLGAP1
DLG associated protein 1
chr14_+_34993240 0.72 ENST00000677647.1
SRP54
signal recognition particle 54
chrM_-_14669 0.72 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr19_-_3557563 0.72 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr3_+_122183664 0.71 ENST00000639785.2
CASR
calcium sensing receptor
chr4_-_36243939 0.70 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_2324642 0.70 ENST00000650485.1
ENST00000649207.1
MYT1L
myelin transcription factor 1 like
chr10_-_114144599 0.68 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr2_-_98663464 0.68 ENST00000414521.6
MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr9_+_79573162 0.67 ENST00000425506.5
TLE4
TLE family member 4, transcriptional corepressor
chr12_-_118190510 0.67 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr1_+_244051275 0.66 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr1_+_177170916 0.64 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr8_-_131040890 0.64 ENST00000286355.10
ADCY8
adenylate cyclase 8
chr4_-_23890035 0.64 ENST00000507380.1
ENST00000264867.7
PPARGC1A
PPARG coactivator 1 alpha
chr1_+_197268204 0.64 ENST00000535699.5
ENST00000538660.5
CRB1
crumbs cell polarity complex component 1
chr6_+_106360668 0.62 ENST00000633556.3
CRYBG1
crystallin beta-gamma domain containing 1
chr19_-_48646155 0.60 ENST00000084798.9
CA11
carbonic anhydrase 11
chr7_-_14974773 0.60 ENST00000437998.1
DGKB
diacylglycerol kinase beta
chr7_-_116159886 0.59 ENST00000484212.5
TFEC
transcription factor EC
chr7_+_138460238 0.58 ENST00000343526.9
TRIM24
tripartite motif containing 24
chr6_+_72216442 0.58 ENST00000425662.6
ENST00000453976.6
RIMS1
regulating synaptic membrane exocytosis 1
chr4_+_41935114 0.57 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
TMEM33
transmembrane protein 33
chr10_-_27240505 0.56 ENST00000375888.5
ENST00000676732.1
ACBD5
acyl-CoA binding domain containing 5
chr3_+_63967738 0.56 ENST00000484332.1
ATXN7
ataxin 7
chr1_-_23799533 0.56 ENST00000429356.5
GALE
UDP-galactose-4-epimerase
chr10_-_88851809 0.55 ENST00000371930.5
ANKRD22
ankyrin repeat domain 22
chr11_-_75089754 0.53 ENST00000305159.3
OR2AT4
olfactory receptor family 2 subfamily AT member 4
chr10_+_87357720 0.52 ENST00000412718.3
ENST00000381697.7
NUTM2D
NUT family member 2D
chr7_-_105691637 0.52 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr1_-_23799561 0.52 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr2_-_2324968 0.51 ENST00000649641.1
MYT1L
myelin transcription factor 1 like
chr15_+_65550819 0.49 ENST00000569894.5
HACD3
3-hydroxyacyl-CoA dehydratase 3
chr11_-_129024157 0.49 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr17_-_66229380 0.49 ENST00000205948.11
APOH
apolipoprotein H
chrX_-_13817027 0.48 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
GPM6B
glycoprotein M6B
chr1_+_197268222 0.47 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
CRB1
crumbs cell polarity complex component 1
chr4_+_157220795 0.47 ENST00000506284.5
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
chr7_+_38977904 0.47 ENST00000518318.7
ENST00000403058.6
POU6F2
POU class 6 homeobox 2
chr6_-_138512493 0.47 ENST00000533765.1
NHSL1
NHS like 1
chr8_-_56211257 0.45 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chr11_+_60056587 0.44 ENST00000395032.6
ENST00000358152.6
MS4A3
membrane spanning 4-domains A3
chr10_-_126670686 0.44 ENST00000488181.3
C10orf90
chromosome 10 open reading frame 90
chr14_+_61697622 0.44 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr2_-_2324935 0.42 ENST00000649709.1
MYT1L
myelin transcription factor 1 like
chr1_-_111488795 0.41 ENST00000472933.2
TMIGD3
transmembrane and immunoglobulin domain containing 3
chr1_+_196888014 0.41 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
CFHR4
complement factor H related 4
chr5_-_88823763 0.41 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr18_-_5197241 0.41 ENST00000434239.4
AKAIN1
A-kinase anchor inhibitor 1
chr11_-_117316230 0.40 ENST00000313005.11
ENST00000528053.5
BACE1
beta-secretase 1
chr14_+_21997531 0.39 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr4_+_94207596 0.37 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr5_+_68290637 0.37 ENST00000336483.9
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr18_+_616672 0.35 ENST00000338387.11
CLUL1
clusterin like 1
chr18_+_616711 0.35 ENST00000579494.1
CLUL1
clusterin like 1
chr12_+_49346911 0.35 ENST00000395069.3
DNAJC22
DnaJ heat shock protein family (Hsp40) member C22
chr3_+_46877705 0.34 ENST00000449590.6
PTH1R
parathyroid hormone 1 receptor
chr1_-_74512611 0.34 ENST00000294635.5
LRRC53
leucine rich repeat containing 53
chr8_-_30812867 0.32 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr19_+_11346499 0.31 ENST00000458408.6
ENST00000586451.5
ENST00000588592.5
CCDC159
coiled-coil domain containing 159
chr3_-_191282383 0.30 ENST00000427544.6
UTS2B
urotensin 2B
chr3_+_101724633 0.30 ENST00000494050.5
CEP97
centrosomal protein 97
chr17_-_30334050 0.30 ENST00000328886.5
ENST00000538566.6
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr11_+_60056653 0.29 ENST00000278865.8
MS4A3
membrane spanning 4-domains A3
chr3_+_46612525 0.27 ENST00000640551.3
FAM240A
family with sequence similarity 240 member A
chr2_-_96505345 0.27 ENST00000310865.7
ENST00000451794.6
NEURL3
neuralized E3 ubiquitin protein ligase 3
chr19_-_11346486 0.27 ENST00000590482.5
TMEM205
transmembrane protein 205
chr3_-_64019334 0.27 ENST00000480205.5
PSMD6
proteasome 26S subunit, non-ATPase 6
chr5_+_148312416 0.27 ENST00000274565.5
SPINK7
serine peptidase inhibitor Kazal type 7
chr6_+_26103922 0.26 ENST00000377803.4
H4C3
H4 clustered histone 3
chr4_-_86357722 0.26 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
MAPK10
mitogen-activated protein kinase 10
chrX_+_85003863 0.26 ENST00000373173.7
APOOL
apolipoprotein O like
chr9_-_113303271 0.26 ENST00000297894.5
ENST00000489339.2
RNF183
ring finger protein 183
chr7_+_92057602 0.26 ENST00000491695.2
AKAP9
A-kinase anchoring protein 9
chr3_+_138621225 0.25 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr19_+_9185594 0.25 ENST00000344248.4
OR7D2
olfactory receptor family 7 subfamily D member 2
chr3_-_47475811 0.25 ENST00000265565.10
ENST00000428413.5
SCAP
SREBF chaperone
chr15_+_64387828 0.24 ENST00000261884.8
TRIP4
thyroid hormone receptor interactor 4
chr1_-_92486916 0.24 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr15_-_55408245 0.24 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
CCPG1
cell cycle progression 1
chrX_+_109535775 0.23 ENST00000218004.5
NXT2
nuclear transport factor 2 like export factor 2
chr8_-_109680812 0.23 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
SYBU
syntabulin
chr16_-_28623330 0.23 ENST00000677940.1
ENSG00000288656.1
novel protein
chr3_+_101724602 0.23 ENST00000341893.8
CEP97
centrosomal protein 97
chr1_-_19923617 0.23 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr14_+_55027576 0.22 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chrX_+_123963164 0.22 ENST00000394478.1
STAG2
stromal antigen 2
chr17_+_37491464 0.21 ENST00000613659.1
DUSP14
dual specificity phosphatase 14
chr3_-_142029108 0.20 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr22_+_23145366 0.19 ENST00000341989.9
ENST00000263116.8
RAB36
RAB36, member RAS oncogene family
chr1_-_182671853 0.18 ENST00000367556.5
RGS8
regulator of G protein signaling 8
chr19_+_11346556 0.17 ENST00000587531.5
CCDC159
coiled-coil domain containing 159
chr5_-_79514127 0.17 ENST00000334082.11
HOMER1
homer scaffold protein 1
chr8_-_30812773 0.16 ENST00000221138.9
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr15_-_75455802 0.16 ENST00000568431.5
ENST00000568309.5
ENST00000568190.1
ENST00000570115.5
ENST00000564778.5
SIN3A
SIN3 transcription regulator family member A
chr15_-_75455767 0.15 ENST00000360439.8
SIN3A
SIN3 transcription regulator family member A
chr1_-_182671902 0.15 ENST00000483095.6
RGS8
regulator of G protein signaling 8
chr11_-_63608542 0.13 ENST00000540943.1
PLAAT3
phospholipase A and acyltransferase 3
chr16_+_67570741 0.11 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CTCF
CCCTC-binding factor
chr12_-_52367478 0.11 ENST00000257901.7
KRT85
keratin 85
chr12_+_55444069 0.11 ENST00000641516.1
ENST00000641202.1
OR6C2
olfactory receptor family 6 subfamily C member 2
chr16_-_1488764 0.11 ENST00000447419.7
ENST00000440447.2
PTX4
pentraxin 4
chr7_+_120273129 0.11 ENST00000331113.9
KCND2
potassium voltage-gated channel subfamily D member 2
chr3_+_158110052 0.11 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
RSRC1
arginine and serine rich coiled-coil 1
chr2_-_50656384 0.10 ENST00000625891.2
NRXN1
neurexin 1
chr8_+_106726115 0.10 ENST00000521592.5
OXR1
oxidation resistance 1
chr18_-_5197502 0.09 ENST00000580650.1
AKAIN1
A-kinase anchor inhibitor 1
chr12_+_55330043 0.09 ENST00000641364.1
OR6C3
olfactory receptor family 6 subfamily C member 3
chr6_-_31120437 0.09 ENST00000376288.3
CDSN
corneodesmosin
chr3_+_41194741 0.08 ENST00000643541.1
ENST00000426215.5
ENST00000645210.1
ENST00000646381.1
ENST00000405570.6
ENST00000642248.1
ENST00000433400.6
CTNNB1
catenin beta 1
chr3_-_20012250 0.08 ENST00000389050.5
PP2D1
protein phosphatase 2C like domain containing 1
chr9_+_69145463 0.07 ENST00000636438.1
TJP2
tight junction protein 2
chr1_-_158426237 0.07 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr1_+_115029823 0.06 ENST00000256592.3
TSHB
thyroid stimulating hormone subunit beta
chrX_+_108045050 0.06 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr11_-_5778667 0.06 ENST00000317093.2
OR52N5
olfactory receptor family 52 subfamily N member 5
chr1_-_158570580 0.06 ENST00000641540.1
OR6P1
olfactory receptor family 6 subfamily P member 1
chr5_+_55853314 0.04 ENST00000354961.8
ENST00000297015.7
IL31RA
interleukin 31 receptor A
chr14_+_55027200 0.04 ENST00000395472.2
ENST00000555846.2
SOCS4
suppressor of cytokine signaling 4
chr1_-_45522870 0.02 ENST00000424390.2
PRDX1
peroxiredoxin 1
chr10_-_45307838 0.01 ENST00000536058.1
OR13A1
olfactory receptor family 13 subfamily A member 1
chr3_+_138621207 0.00 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr1_+_207325629 0.00 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr5_+_167284799 0.00 ENST00000518659.5
TENM2
teneurin transmembrane protein 2
chr13_-_70108441 0.00 ENST00000377844.9
ENST00000545028.2
KLHL1
kelch like family member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.6 1.7 GO:1903123 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.5 1.4 GO:0071250 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) response to resveratrol(GO:1904638) cellular response to resveratrol(GO:1904639) positive regulation of progesterone biosynthetic process(GO:2000184)
0.4 1.1 GO:1903442 response to methylamine(GO:0036255) response to lipoic acid(GO:1903442)
0.3 1.0 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.3 1.2 GO:1900148 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.2 1.5 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.2 2.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 6.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 2.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.7 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.9 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.2 1.8 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.2 0.5 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.6 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 1.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 3.8 GO:0043486 histone exchange(GO:0043486)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.0 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 2.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 2.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 1.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.5 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 3.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.5 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584) regulation of molecular function, epigenetic(GO:0040030)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 1.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 1.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403) fungiform papilla formation(GO:0061198) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 1.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0032473 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.5 1.4 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.4 2.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 1.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 2.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:1990246 uniplex complex(GO:1990246)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.0 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 2.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.9 2.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.6 1.8 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.6 1.7 GO:0036479 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.4 1.1 GO:0070279 glycine dehydrogenase (decarboxylating) activity(GO:0004375) oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor(GO:0016642) vitamin B6 binding(GO:0070279) pyridoxal binding(GO:0070280)
0.3 1.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 1.5 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.2 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 6.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.8 GO:0042806 fucose binding(GO:0042806)
0.1 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 3.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.5 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 3.8 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.0 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 5.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis