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avrg: Illumina Body Map 2 (GSE30611)

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Results for MAFF_MAFG

Z-value: 1.63

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Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
MAFF
ENSG00000185022.12 MAFF
MAFG
ENSG00000197063.11 MAFG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFGhg38_v1_chr17_-_81923532_81923547-0.212.5e-01Click!
MAFFhg38_v1_chr22_+_38213530_382135410.183.3e-01Click!

Activity profile of MAFF_MAFG motif

Sorted Z-values of MAFF_MAFG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFF_MAFG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrY_+_2841594 8.97 ENST00000250784.13
RPS4Y1
ribosomal protein S4 Y-linked 1
chr22_+_22811737 4.80 ENST00000390315.3
IGLV3-10
immunoglobulin lambda variable 3-10
chrY_+_2841864 4.02 ENST00000430575.1
RPS4Y1
ribosomal protein S4 Y-linked 1
chr1_+_22653228 3.40 ENST00000509305.6
C1QB
complement C1q B chain
chr1_+_22653189 3.31 ENST00000432749.6
C1QB
complement C1q B chain
chr2_+_102337148 3.07 ENST00000311734.6
ENST00000409584.5
IL1RL1
interleukin 1 receptor like 1
chr22_+_22195753 2.77 ENST00000390285.4
IGLV6-57
immunoglobulin lambda variable 6-57
chrX_+_139530730 2.71 ENST00000218099.7
F9
coagulation factor IX
chrX_+_139530752 2.31 ENST00000394090.2
F9
coagulation factor IX
chr12_+_20815672 2.30 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
SLCO1B3
SLCO1B3-SLCO1B7
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr7_+_1044542 2.25 ENST00000444847.2
GPR146
G protein-coupled receptor 146
chr22_+_22668286 2.19 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr16_-_56668034 2.15 ENST00000569500.5
ENST00000379811.4
ENST00000444837.6
MT1G
metallothionein 1G
chr22_+_22409755 2.12 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr1_+_196943738 2.10 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
CFHR2
complement factor H related 2
chr4_+_73409340 2.09 ENST00000511370.1
ALB
albumin
chr1_+_196819731 1.75 ENST00000320493.10
ENST00000367424.4
CFHR1
complement factor H related 1
chr2_+_119431846 1.74 ENST00000306406.5
TMEM37
transmembrane protein 37
chr5_-_42811884 1.72 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr14_-_106422175 1.72 ENST00000390619.2
IGHV4-39
immunoglobulin heavy variable 4-39
chr11_-_5227063 1.69 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr10_-_79560386 1.63 ENST00000372327.9
ENST00000417041.1
ENST00000640627.1
ENST00000372325.7
SFTPA2
surfactant protein A2
chr11_+_75717811 1.62 ENST00000198801.10
MOGAT2
monoacylglycerol O-acyltransferase 2
chr2_+_210556590 1.61 ENST00000233072.10
ENST00000619804.1
CPS1
carbamoyl-phosphate synthase 1
chr20_+_62656359 1.55 ENST00000370507.5
SLCO4A1
solute carrier organic anion transporter family member 4A1
chr6_+_131573219 1.54 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
ARG1
arginase 1
chr16_+_56682461 1.53 ENST00000562939.1
ENST00000394485.5
ENST00000567563.1
MT1X
ENSG00000259827.1
metallothionein 1X
novel transcript
chr2_+_90172802 1.50 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr10_+_79610932 1.36 ENST00000428376.6
ENST00000398636.8
ENST00000419470.6
ENST00000429958.5
SFTPA1
surfactant protein A1
chr16_+_82035245 1.34 ENST00000199936.9
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr11_-_10568650 1.34 ENST00000256178.8
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_60280531 1.34 ENST00000532114.6
MS4A4A
membrane spanning 4-domains A4A
chr9_-_101442403 1.32 ENST00000648758.1
ALDOB
aldolase, fructose-bisphosphate B
chr12_+_103587266 1.29 ENST00000388887.7
STAB2
stabilin 2
chr1_+_119368773 1.26 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
HAO2
hydroxyacid oxidase 2
chr11_-_10568571 1.26 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr22_+_22818994 1.24 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9
chr11_+_60280577 1.22 ENST00000679988.1
MS4A4A
membrane spanning 4-domains A4A
chr4_+_155854758 1.10 ENST00000506072.5
ENST00000507590.5
TDO2
tryptophan 2,3-dioxygenase
chr14_-_106277039 1.08 ENST00000390610.2
IGHV1-24
immunoglobulin heavy variable 1-24
chr2_-_87825952 1.08 ENST00000398146.4
RGPD2
RANBP2 like and GRIP domain containing 2
chr7_-_22194709 1.07 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr14_-_106622837 1.05 ENST00000390628.3
IGHV1-58
immunoglobulin heavy variable 1-58
chr11_-_914774 1.02 ENST00000528154.1
ENST00000525840.1
CHID1
chitinase domain containing 1
chr1_+_119368802 1.02 ENST00000361035.8
ENST00000419144.1
HAO2
HAO2-IT1
hydroxyacid oxidase 2
HAO2 intronic transcript 1
chr14_+_94110728 1.01 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
IFI27
interferon alpha inducible protein 27
chr22_+_22357739 1.00 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr9_-_101442372 0.99 ENST00000648423.1
ALDOB
aldolase, fructose-bisphosphate B
chr22_+_22720615 0.99 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr2_-_169031317 0.97 ENST00000650372.1
ABCB11
ATP binding cassette subfamily B member 11
chr22_+_22431949 0.95 ENST00000390301.3
IGLV1-36
immunoglobulin lambda variable 1-36
chr16_+_82034978 0.95 ENST00000563491.5
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr22_+_22030934 0.93 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr2_-_68952880 0.93 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr16_+_82035267 0.92 ENST00000566213.1
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr1_+_86547070 0.92 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr11_+_60280658 0.91 ENST00000337908.5
MS4A4A
membrane spanning 4-domains A4A
chr1_-_62319425 0.89 ENST00000371153.9
KANK4
KN motif and ankyrin repeat domains 4
chr12_-_21941300 0.88 ENST00000684084.1
ABCC9
ATP binding cassette subfamily C member 9
chr2_+_90038848 0.87 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr12_-_21941402 0.86 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ABCC9
ATP binding cassette subfamily C member 9
chr9_-_101430861 0.85 ENST00000649902.1
ALDOB
aldolase, fructose-bisphosphate B
chr4_-_170003738 0.84 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr15_+_34225050 0.84 ENST00000559421.1
EMC4
ER membrane protein complex subunit 4
chr5_-_115816650 0.84 ENST00000250535.5
CDO1
cysteine dioxygenase type 1
chr2_+_127419686 0.84 ENST00000427769.5
PROC
protein C, inactivator of coagulation factors Va and VIIIa
chr6_+_160121859 0.83 ENST00000324965.8
ENST00000457470.6
SLC22A1
solute carrier family 22 member 1
chr15_+_23565705 0.83 ENST00000568252.1
ENST00000649065.1
MKRN3
makorin ring finger protein 3
chr14_-_106005574 0.79 ENST00000390595.3
IGHV1-3
immunoglobulin heavy variable 1-3
chr1_+_56854764 0.78 ENST00000361249.4
C8A
complement C8 alpha chain
chr19_-_15464525 0.78 ENST00000343625.12
RASAL3
RAS protein activator like 3
chr19_-_7747511 0.78 ENST00000593660.5
ENST00000204801.12
ENST00000315591.12
ENST00000354397.10
ENST00000394161.9
ENST00000593821.5
ENST00000602261.5
ENST00000601256.1
ENST00000601951.5
ENST00000315599.12
CD209
CD209 molecule
chr2_+_191678122 0.78 ENST00000425611.9
ENST00000410026.7
NABP1
nucleic acid binding protein 1
chr12_-_10098977 0.77 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr22_+_22686724 0.77 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr6_+_160121809 0.76 ENST00000366963.9
SLC22A1
solute carrier family 22 member 1
chr2_+_191678152 0.76 ENST00000409510.5
NABP1
nucleic acid binding protein 1
chr2_-_88992903 0.75 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr4_-_186596770 0.73 ENST00000512772.5
FAT1
FAT atypical cadherin 1
chr15_+_58431985 0.71 ENST00000433326.2
ENST00000299022.10
LIPC
lipase C, hepatic type
chr22_+_22327298 0.71 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr7_-_35254074 0.69 ENST00000408931.4
TBX20
T-box transcription factor 20
chr9_-_34376878 0.67 ENST00000297625.8
MYORG
myogenesis regulating glycosidase (putative)
chr19_+_38930916 0.67 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr7_-_22500152 0.66 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP1B
STEAP family member 1B
chr1_-_62319264 0.66 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr12_-_10098940 0.66 ENST00000420265.2
CLEC1A
C-type lectin domain family 1 member A
chr16_-_20327426 0.64 ENST00000575582.5
ENST00000341642.9
ENST00000381362.8
ENST00000572347.5
ENST00000572478.5
ENST00000302555.10
GP2
glycoprotein 2
chr11_-_85665077 0.64 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr5_-_176630364 0.64 ENST00000310112.7
SNCB
synuclein beta
chr11_+_10305065 0.63 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
ADM
adrenomedullin
chr7_-_13986498 0.63 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETV1
ETS variant transcription factor 1
chr11_-_5243644 0.63 ENST00000643122.1
HBD
hemoglobin subunit delta
chr7_-_122886706 0.62 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
CADPS2
calcium dependent secretion activator 2
chr16_+_396743 0.62 ENST00000454619.5
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr10_+_122560639 0.61 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr1_+_40396766 0.61 ENST00000539317.2
SMAP2
small ArfGAP2
chr2_-_3519521 0.60 ENST00000327435.11
ADI1
acireductone dioxygenase 1
chr15_+_84884648 0.60 ENST00000338602.6
ENST00000538177.5
ENST00000394573.6
SLC28A1
solute carrier family 28 member 1
chr5_+_100535317 0.60 ENST00000312637.5
FAM174A
family with sequence similarity 174 member A
chr2_+_233671879 0.59 ENST00000354728.5
UGT1A9
UDP glucuronosyltransferase family 1 member A9
chr22_+_22747383 0.58 ENST00000390311.3
IGLV3-16
immunoglobulin lambda variable 3-16
chr6_-_47309898 0.58 ENST00000296861.2
TNFRSF21
TNF receptor superfamily member 21
chr19_-_14057573 0.57 ENST00000589048.2
PALM3
paralemmin 3
chr7_+_1055285 0.57 ENST00000397095.2
GPR146
G protein-coupled receptor 146
chr19_+_827823 0.57 ENST00000233997.4
AZU1
azurocidin 1
chr11_+_124919244 0.57 ENST00000408930.6
HEPN1
hepatocellular carcinoma, down-regulated 1
chr12_+_55681647 0.56 ENST00000614691.1
METTL7B
methyltransferase like 7B
chr16_+_396713 0.56 ENST00000397722.5
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr4_+_73481737 0.56 ENST00000226355.5
AFM
afamin
chr10_-_67838173 0.55 ENST00000225171.7
DNAJC12
DnaJ heat shock protein family (Hsp40) member C12
chr18_+_23928625 0.55 ENST00000588164.2
LAMA3
laminin subunit alpha 3
chr16_-_28597042 0.54 ENST00000533150.5
ENST00000335715.9
SULT1A2
sulfotransferase family 1A member 2
chr5_-_176630517 0.54 ENST00000393693.7
ENST00000614675.4
SNCB
synuclein beta
chr7_-_122886439 0.53 ENST00000412584.6
ENST00000449022.7
CADPS2
calcium dependent secretion activator 2
chr12_+_55681711 0.53 ENST00000394252.4
METTL7B
methyltransferase like 7B
chr16_+_28638065 0.53 ENST00000683297.1
NPIPB8
nuclear pore complex interacting protein family member B8
chr19_+_35118456 0.53 ENST00000604621.5
FXYD3
FXYD domain containing ion transport regulator 3
chr1_-_203186677 0.53 ENST00000255409.8
CHI3L1
chitinase 3 like 1
chr17_+_74987581 0.52 ENST00000337231.5
CDR2L
cerebellar degeneration related protein 2 like
chr3_-_150546403 0.51 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
SERP1
stress associated endoplasmic reticulum protein 1
chr17_-_4786354 0.51 ENST00000328739.6
ENST00000441199.2
ENST00000416307.6
VMO1
vitelline membrane outer layer 1 homolog
chr17_-_17582417 0.50 ENST00000395783.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr2_-_164841410 0.50 ENST00000342193.8
ENST00000375458.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr16_+_30199860 0.50 ENST00000395138.6
SULT1A3
sulfotransferase family 1A member 3
chr7_-_122098831 0.50 ENST00000681213.1
ENST00000679419.1
AASS
aminoadipate-semialdehyde synthase
chr17_-_14236862 0.49 ENST00000420162.7
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr19_-_7747559 0.49 ENST00000394173.8
CD209
CD209 molecule
chr13_+_43879552 0.49 ENST00000425906.1
LACC1
laccase domain containing 1
chr22_+_22375984 0.48 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr22_-_26618026 0.47 ENST00000647684.1
CRYBB1
crystallin beta B1
chr19_+_43353678 0.47 ENST00000618265.5
ENST00000607855.5
CD177
CD177 molecule
chr19_-_38930737 0.47 ENST00000430193.7
ENST00000600042.5
ENST00000221431.11
SARS2
seryl-tRNA synthetase 2, mitochondrial
chr17_+_50373214 0.47 ENST00000393271.6
ENST00000338165.9
ENST00000511519.6
EME1
essential meiotic structure-specific endonuclease 1
chr16_+_397183 0.46 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME4
NME/NM23 nucleoside diphosphate kinase 4
chr3_-_50340933 0.45 ENST00000616212.4
RASSF1
Ras association domain family member 1
chr5_+_176630618 0.45 ENST00000647833.1
ENST00000318682.11
EIF4E1B
eukaryotic translation initiation factor 4E family member 1B
chr7_-_5425404 0.45 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr15_+_32718476 0.45 ENST00000652365.1
GREM1
gremlin 1, DAN family BMP antagonist
chr6_-_138107412 0.45 ENST00000421351.4
PERP
p53 apoptosis effector related to PMP22
chr5_+_35856883 0.45 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_+_38039199 0.45 ENST00000346219.7
ENST00000308059.11
DLEC1
DLEC1 cilia and flagella associated protein
chr2_-_68319887 0.44 ENST00000409862.1
ENST00000263655.4
CNRIP1
cannabinoid receptor interacting protein 1
chr2_-_175005357 0.44 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
CHN1
chimerin 1
chr3_-_119677346 0.44 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
COX17
cytochrome c oxidase copper chaperone COX17
chr19_-_17255448 0.42 ENST00000594059.1
ENSG00000269095.1
novel protein
chr20_-_57620393 0.42 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr11_-_914812 0.41 ENST00000533059.5
CHID1
chitinase domain containing 1
chr6_+_30983710 0.41 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr14_-_106269133 0.41 ENST00000390609.3
IGHV3-23
immunoglobulin heavy variable 3-23
chr15_+_84884672 0.41 ENST00000286749.3
SLC28A1
solute carrier family 28 member 1
chr11_+_10305370 0.41 ENST00000528544.1
ADM
adrenomedullin
chr4_-_25160546 0.41 ENST00000681948.1
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr2_+_201116396 0.41 ENST00000395148.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr22_+_22343185 0.40 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr7_-_1160144 0.40 ENST00000397083.6
ENST00000401903.5
ENST00000316495.8
ZFAND2A
zinc finger AN1-type containing 2A
chr11_-_114400417 0.40 ENST00000325636.8
ENST00000623205.2
C11orf71
chromosome 11 open reading frame 71
chr17_+_74748648 0.39 ENST00000583369.5
SLC9A3R1
SLC9A3 regulator 1
chr1_+_81699665 0.39 ENST00000359929.7
ADGRL2
adhesion G protein-coupled receptor L2
chr3_+_111732474 0.39 ENST00000393923.7
PHLDB2
pleckstrin homology like domain family B member 2
chr22_+_22427517 0.39 ENST00000390300.2
IGLV5-37
immunoglobulin lambda variable 5-37
chr13_+_42048645 0.39 ENST00000337343.9
ENST00000261491.9
ENST00000611224.1
DGKH
diacylglycerol kinase eta
chr8_-_64798725 0.39 ENST00000310193.4
CYP7B1
cytochrome P450 family 7 subfamily B member 1
chr14_+_94581880 0.39 ENST00000557598.1
ENST00000556064.1
SERPINA5
serpin family A member 5
chr18_-_59359245 0.39 ENST00000251047.6
LMAN1
lectin, mannose binding 1
chr10_-_14548646 0.39 ENST00000378470.5
FAM107B
family with sequence similarity 107 member B
chrX_-_135022473 0.38 ENST00000391440.3
RTL8B
retrotransposon Gag like 8B
chr16_+_56651885 0.38 ENST00000334346.3
ENST00000562399.1
MT1B
metallothionein 1B
chr11_+_2382460 0.38 ENST00000492627.5
CD81
CD81 molecule
chr15_-_92655712 0.38 ENST00000327355.6
FAM174B
family with sequence similarity 174 member B
chr16_-_20327801 0.38 ENST00000381360.9
GP2
glycoprotein 2
chr5_+_111073309 0.38 ENST00000379706.4
TSLP
thymic stromal lymphopoietin
chr1_+_206583255 0.37 ENST00000581888.1
RASSF5
Ras association domain family member 5
chr14_-_23034878 0.37 ENST00000493471.2
ENST00000460922.2
ENST00000361611.11
PSMB5
proteasome 20S subunit beta 5
chr6_+_12957301 0.37 ENST00000676234.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_64452338 0.37 ENST00000540417.1
ENST00000678368.1
ENST00000539810.1
TBK1
TANK binding kinase 1
chr1_+_201283452 0.36 ENST00000263946.7
ENST00000367324.8
PKP1
plakophilin 1
chr1_+_151036578 0.36 ENST00000368931.8
ENST00000295294.11
BNIPL
BCL2 interacting protein like
chr18_-_66604076 0.36 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
CDH19
cadherin 19
chr7_-_13986439 0.36 ENST00000443608.5
ENST00000438956.5
ETV1
ETS variant transcription factor 1
chr2_-_217901986 0.36 ENST00000439083.5
TNS1
tensin 1
chr7_+_100602344 0.36 ENST00000223061.6
PCOLCE
procollagen C-endopeptidase enhancer
chr3_-_58577367 0.36 ENST00000464064.5
ENST00000360997.7
FAM107A
family with sequence similarity 107 member A
chr3_-_50340804 0.36 ENST00000359365.9
ENST00000357043.6
RASSF1
Ras association domain family member 1
chr12_-_43806249 0.35 ENST00000548315.5
ENST00000552521.5
ENST00000546662.5
ENST00000548403.1
ENST00000546506.5
ENST00000395510.7
TWF1
twinfilin actin binding protein 1
chr1_-_204494752 0.35 ENST00000684373.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr17_-_4786433 0.35 ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog
chr19_+_6531018 0.35 ENST00000245817.5
TNFSF9
TNF superfamily member 9
chr17_+_16380854 0.35 ENST00000577640.1
UBB
ubiquitin B
chr17_+_76384601 0.35 ENST00000592299.6
ENST00000590959.5
ENST00000323374.8
SPHK1
sphingosine kinase 1
chr3_+_121567924 0.34 ENST00000334384.5
ARGFX
arginine-fifty homeobox
chr16_+_57358775 0.34 ENST00000219235.5
CCL22
C-C motif chemokine ligand 22
chr12_-_10674013 0.34 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
STYK1
serine/threonine/tyrosine kinase 1
chr5_-_14011743 0.34 ENST00000681290.1
DNAH5
dynein axonemal heavy chain 5
chr7_+_40134966 0.34 ENST00000401647.7
ENST00000628514.3
ENST00000335693.9
ENST00000416370.2
SUGCT
succinyl-CoA:glutarate-CoA transferase
chr6_+_150599861 0.34 ENST00000367326.1
PLEKHG1
pleckstrin homology and RhoGEF domain containing G1
chr19_-_50511203 0.34 ENST00000595669.5
JOSD2
Josephin domain containing 2
chr15_+_32717994 0.34 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr5_-_45696326 0.33 ENST00000673735.1
ENST00000303230.6
HCN1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
chr2_-_74529670 0.33 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 1.6 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.5 5.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 1.7 GO:0030185 nitric oxide transport(GO:0030185)
0.4 1.5 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.4 3.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 1.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 1.3 GO:0046968 peptide antigen transport(GO:0046968)
0.3 3.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 0.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.3 3.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 0.8 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3 0.8 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.2 1.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.7 GO:0021524 pulmonary valve formation(GO:0003193) visceral motor neuron differentiation(GO:0021524) foramen ovale closure(GO:0035922)
0.2 1.6 GO:0048241 epinephrine transport(GO:0048241)
0.2 1.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.2 0.8 GO:0042412 taurine biosynthetic process(GO:0042412)
0.2 0.8 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 1.0 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.2 0.6 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.2 0.9 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 0.8 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.4 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.1 1.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.1 23.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 2.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 2.2 GO:0071280 cellular response to copper ion(GO:0071280)
0.1 1.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 3.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.7 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 1.4 GO:0008228 opsonization(GO:0008228)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.3 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.1 1.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 11.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 0.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.2 GO:0060302 negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.2 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.1 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.4 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.3 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 2.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 10.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.2 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) negative regulation of activation of membrane attack complex(GO:0001971)
0.0 1.0 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.7 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:2001179 regulation of interleukin-10 secretion(GO:2001179) positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.2 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 1.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 2.3 GO:0019395 fatty acid catabolic process(GO:0009062) fatty acid oxidation(GO:0019395)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.0 GO:0048561 establishment of organ orientation(GO:0048561)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 GO:0005602 complement component C1 complex(GO:0005602)
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.5 GO:0070876 SOSS complex(GO:0070876)
0.2 2.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 12.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.0 GO:0042599 lamellar body(GO:0042599)
0.1 0.4 GO:0036024 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.2 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 0.2 GO:1990696 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0070449 elongin complex(GO:0070449)
0.0 6.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 6.1 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia tip link(GO:0002140) myosin VII complex(GO:0031477) stereocilia tip-link density(GO:1990427) upper tip-link density(GO:1990435)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 6.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.9 GO:0045178 basal part of cell(GO:0045178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.8 3.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.8 2.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.6 3.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.6 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 1.6 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.4 2.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.0 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.3 1.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.2 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.6 GO:0035375 zymogen binding(GO:0035375)
0.2 0.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 1.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 1.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.5 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 1.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 13.0 GO:0019843 rRNA binding(GO:0019843)
0.1 0.6 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.1 GO:0004568 chitinase activity(GO:0004568)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 2.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.6 GO:1903136 cuprous ion binding(GO:1903136)
0.1 1.6 GO:1901612 cardiolipin binding(GO:1901612)
0.1 26.6 GO:0003823 antigen binding(GO:0003823)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 1.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550) indanol dehydrogenase activity(GO:0047718)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0070404 NADH binding(GO:0070404)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 13.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 1.0 GO:0001848 complement binding(GO:0001848)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 10.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 5.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 12.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 3.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane