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avrg: Illumina Body Map 2 (GSE30611)

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Results for MECOM

Z-value: 1.63

Motif logo

Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
ENSG00000085276.19 MECOM

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg38_v1_chr3_-_169663704_1696637750.281.2e-01Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_-_55182442 6.09 ENST00000545075.3
MT-RNR2 like 10
chr1_-_237945275 5.27 ENST00000604646.1
MT-RNR2 like 11
chr4_-_87528619 4.82 ENST00000535835.5
SPARC like 1
chr17_+_22523404 3.99 ENST00000540040.3
MT-RNR2 like 1
chr11_-_5227063 3.57 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr20_-_57359491 3.42 ENST00000543500.3
MT-RNR2 like 3
chr7_+_142666272 3.02 ENST00000604952.1
MT-RNR2 like 6
chr1_+_86468902 2.97 ENST00000394711.2
chloride channel accessory 1
chr4_-_87529092 2.76 ENST00000503414.5
SPARC like 1
chr17_-_68955332 2.60 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr4_-_87529220 2.40 ENST00000543631.5
SPARC like 1
chr12_-_14885845 2.27 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr11_-_10509180 2.17 ENST00000536684.3
MT-RNR2 like 8
chr12_+_7062583 2.12 ENST00000542978.1
complement C1s
chr8_-_6563238 2.12 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr3_+_148865288 2.06 ENST00000296046.4
carboxypeptidase A3
chr14_+_66486356 1.98 ENST00000636229.1
coiled-coil domain containing 196
chr2_+_28778848 1.97 ENST00000418910.1
protein phosphatase 1 catalytic subunit beta
chr8_-_6563044 1.64 ENST00000338312.10
angiopoietin 2
chr2_+_188974364 1.61 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr8_-_38150943 1.59 ENST00000276449.9
steroidogenic acute regulatory protein
chr10_-_86957582 1.55 ENST00000372027.10
multimerin 2
chr8_-_94262308 1.54 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr17_+_9021501 1.46 ENST00000173229.7
netrin 1
chr3_-_96618225 1.46 ENST00000600213.3
MT-RNR2 like 12
chr2_-_55923775 1.45 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr10_-_20897288 1.43 ENST00000377122.9
nebulette
chr12_-_86256299 1.39 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr8_-_6563409 1.38 ENST00000325203.9
angiopoietin 2
chr7_-_120858066 1.38 ENST00000222747.8
tetraspanin 12
chr3_+_99638475 1.33 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
collagen type VIII alpha 1 chain
chr9_+_127611760 1.32 ENST00000625363.2
ENST00000626539.3
syntaxin binding protein 1
chr4_+_70334963 1.31 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr7_+_97732046 1.31 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chrX_-_43882411 1.31 ENST00000378069.5
monoamine oxidase B
chr9_+_33240159 1.24 ENST00000379721.4
serine peptidase inhibitor Kazal type 4
chr2_-_223602284 1.21 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr1_+_172452885 1.19 ENST00000367725.4
chromosome 1 open reading frame 105
chr1_+_81800368 1.17 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr17_-_39152571 1.15 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr12_-_10167591 1.14 ENST00000543993.5
ENST00000339968.6
oxidized low density lipoprotein receptor 1
chr16_+_56191476 1.14 ENST00000262493.12
G protein subunit alpha o1
chr12_-_8662703 1.13 ENST00000535336.5
microfibril associated protein 5
chr15_-_64381431 1.11 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr19_+_47994625 1.11 ENST00000339841.7
epididymal sperm binding protein 1
chrX_-_50200988 1.09 ENST00000358526.7
A-kinase anchoring protein 4
chr19_+_47994696 1.09 ENST00000596043.5
ENST00000597519.5
epididymal sperm binding protein 1
chr6_+_152697888 1.09 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr6_+_44342639 1.07 ENST00000674044.1
ENST00000515220.5
ENST00000323108.12
spermatogenesis associated serine rich 1
chr4_+_116298876 1.06 ENST00000604093.2
MT-RNR2 like 13
chr12_-_15712910 1.05 ENST00000543612.5
epidermal growth factor receptor pathway substrate 8
chr1_+_74235377 1.04 ENST00000326637.8
TNNI3 interacting kinase
chr18_-_27143024 1.02 ENST00000581714.5
carbohydrate sulfotransferase 9
chr5_+_141223332 1.02 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr10_-_48914232 1.01 ENST00000374160.7
leucine rich repeat containing 18
chr7_-_8262533 1.00 ENST00000447326.5
ENST00000406470.6
ENST00000407906.5
islet cell autoantigen 1
chr6_+_152697934 0.99 ENST00000532295.1
MYC target 1
chr1_-_68497030 0.99 ENST00000456315.7
ENST00000525124.1
ENST00000370966.9
DEP domain containing 1
chr3_-_119660580 0.98 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr12_+_12049855 0.96 ENST00000586576.5
ENST00000464885.6
BCL2 like 14
chr12_-_85036246 0.96 ENST00000547836.1
ENST00000532498.7
tetraspanin 19
chr16_+_2817230 0.96 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr9_+_19409000 0.96 ENST00000340967.3
alkaline ceramidase 2
chr9_-_110208156 0.93 ENST00000400613.5
chromosome 9 open reading frame 152
chr9_-_92482499 0.92 ENST00000375544.7
asporin
chr3_+_119294337 0.91 ENST00000264245.9
Rho GTPase activating protein 31
chr12_+_106582996 0.90 ENST00000392842.6
regulatory factor X4
chr11_+_125833308 0.90 ENST00000534411.5
ENST00000457514.3
prostate and testis expressed 4
chrX_+_30243715 0.89 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr8_-_27258386 0.88 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr5_+_119629552 0.88 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chrX_+_102247167 0.87 ENST00000625106.4
nuclear RNA export factor 2
chr14_-_25010604 0.86 ENST00000550887.5
syntaxin binding protein 6
chr19_-_14206168 0.86 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr12_-_112006024 0.85 ENST00000550800.6
ENST00000550037.5
ENST00000549425.5
transmembrane protein 116
chr8_-_39838201 0.85 ENST00000347580.8
ENST00000379853.6
ENST00000265708.9
ENST00000521880.5
ADAM metallopeptidase domain 2
chr9_-_13175824 0.84 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr13_+_101489940 0.83 ENST00000376162.7
integrin subunit beta like 1
chr1_-_153616289 0.83 ENST00000368701.5
ENST00000344616.4
S100 calcium binding protein A14
chr15_+_71547226 0.83 ENST00000357769.4
ENST00000261862.7
thrombospondin type 1 domain containing 4
chr11_-_95923763 0.82 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr2_+_55519610 0.81 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr16_+_14186707 0.79 ENST00000572567.5
myocardin related transcription factor B
chrX_-_102439932 0.79 ENST00000602195.5
nuclear RNA export factor 2B
chr9_-_92482350 0.78 ENST00000375543.2
asporin
chr10_+_29289061 0.78 ENST00000375500.8
ENST00000649382.2
lysozyme like 1
chr15_-_29968864 0.78 ENST00000356107.11
tight junction protein 1
chr2_+_171687784 0.78 ENST00000435234.5
ENST00000443458.5
ENST00000412370.5
dynein cytoplasmic 1 intermediate chain 2
chr7_+_17298642 0.78 ENST00000242057.9
aryl hydrocarbon receptor
chr12_-_86256267 0.77 ENST00000620241.4
MGAT4 family member C
chr19_+_49527988 0.75 ENST00000270645.8
reticulocalbin 3
chr6_-_31546716 0.75 ENST00000483251.1
ATPase H+ transporting V1 subunit G2
chr3_-_109316505 0.75 ENST00000478945.1
developmental pluripotency associated 2
chr1_-_248303424 0.75 ENST00000641276.1
olfactory receptor family 2 subfamily T member 12
chr6_+_69232406 0.74 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr16_+_2817180 0.74 ENST00000450020.7
serine protease 21
chr11_+_17295322 0.72 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chr13_-_60013178 0.72 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr2_+_55519586 0.72 ENST00000339012.7
cilia and flagella associated protein 36
chr5_+_168529299 0.72 ENST00000338333.5
fibrillarin like 1
chrX_+_102307022 0.72 ENST00000604790.2
nuclear RNA export factor 2
chr8_-_121641424 0.70 ENST00000303924.5
hyaluronan synthase 2
chr1_-_153615858 0.69 ENST00000476873.5
S100 calcium binding protein A14
chr12_-_95551417 0.68 ENST00000258499.8
ubiquitin specific peptidase 44
chr9_-_24545866 0.68 ENST00000543880.7
ENST00000418122.1
IZUMO family member 3
chr15_-_78811415 0.67 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr2_+_171687672 0.67 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr12_-_52903648 0.66 ENST00000546900.1
keratin 8
chr1_+_171090892 0.66 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chrX_+_15507302 0.65 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr6_+_49463360 0.63 ENST00000335783.4
centromere protein Q
chr7_-_5967204 0.63 ENST00000337579.4
radial spoke head 10 homolog B
chr19_-_35490456 0.62 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr3_-_149670877 0.62 ENST00000475579.1
WW domain containing transcription regulator 1
chr3_+_29281360 0.62 ENST00000445033.5
RNA binding motif single stranded interacting protein 3
chr2_+_171687457 0.61 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr2_-_174915283 0.61 ENST00000490654.1
ENST00000652756.1
chimerin 1
chr6_-_56542802 0.60 ENST00000524186.1
dystonin
chr5_+_122129533 0.59 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr5_+_102865805 0.58 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr2_+_36696686 0.58 ENST00000379242.7
ENST00000389975.7
vitrin
chr1_+_3752441 0.58 ENST00000294600.7
coiled-coil domain containing 27
chr19_+_15010720 0.58 ENST00000292574.4
coiled-coil domain containing 105
chr12_+_85036310 0.58 ENST00000393212.7
ENST00000393217.7
leucine rich repeats and IQ motif containing 1
chr12_+_72272360 0.56 ENST00000547300.2
ENST00000261180.10
thyrotropin releasing hormone degrading enzyme
chr17_-_3104422 0.56 ENST00000641064.1
ENST00000641833.1
olfactory receptor family 1 subfamily D member 2
chr12_+_93572664 0.55 ENST00000551556.2
suppressor of cytokine signaling 2
chr2_+_171687409 0.55 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chr9_+_116153783 0.54 ENST00000328252.4
pappalysin 1
chr10_+_76318330 0.53 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr4_+_188139438 0.53 ENST00000332517.4
tripartite motif family like 1
chr6_-_75202792 0.53 ENST00000416123.6
collagen type XII alpha 1 chain
chr7_-_101200912 0.52 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr14_-_75980993 0.51 ENST00000556285.1
transforming growth factor beta 3
chr2_+_27582969 0.51 ENST00000556601.5
ENST00000413371.6
ENST00000416005.6
zinc finger protein 512
chr6_-_52995170 0.51 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr9_-_92482461 0.50 ENST00000651738.1
asporin
chr9_+_127264740 0.50 ENST00000373387.9
GTPase activating Rap/RanGAP domain like 3
chr7_+_6757590 0.50 ENST00000297186.7
radial spoke head 10 homolog B2
chr3_-_45842066 0.50 ENST00000445698.1
ENST00000296135.11
leucine zipper transcription factor like 1
chr9_-_127578989 0.49 ENST00000373314.7
niban apoptosis regulator 2
chr10_-_67696115 0.49 ENST00000433211.7
catenin alpha 3
chr12_+_32485963 0.49 ENST00000531134.7
FYVE, RhoGEF and PH domain containing 4
chr3_+_97439603 0.49 ENST00000514100.5
EPH receptor A6
chr1_-_90717296 0.48 ENST00000370445.5
BarH like homeobox 2
chr7_-_29969232 0.47 ENST00000409497.5
secernin 1
chr2_+_171687501 0.47 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr2_+_27583015 0.47 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
zinc finger protein 512
novel transcript
chr10_+_55599041 0.46 ENST00000512524.4
MT-RNR2 like 5
chr16_+_19285724 0.45 ENST00000636231.2
ENST00000493231.5
ENST00000465414.1
C-type lectin domain containing 19A
chr6_-_87095059 0.45 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr6_+_29657120 0.45 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chr11_+_60378524 0.45 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr6_-_154510675 0.44 ENST00000607772.6
CNKSR family member 3
chr10_-_99235846 0.44 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr20_+_34241390 0.43 ENST00000374954.4
agouti signaling protein
chr11_+_94567362 0.43 ENST00000299001.11
piwi like RNA-mediated gene silencing 4
chr12_+_6924449 0.43 ENST00000356654.8
atrophin 1
chr17_+_55267584 0.43 ENST00000575345.5
HLF transcription factor, PAR bZIP family member
chr12_-_10167657 0.42 ENST00000538745.5
oxidized low density lipoprotein receptor 1
chr6_+_44342684 0.42 ENST00000288390.2
spermatogenesis associated serine rich 1
chr15_+_70892809 0.42 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr7_+_91264426 0.41 ENST00000287934.4
frizzled class receptor 1
chr9_+_79571767 0.41 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr5_+_172194172 0.41 ENST00000398186.5
EF-hand calcium binding domain 9
chr7_-_113086815 0.40 ENST00000424100.2
G protein-coupled receptor 85
chr2_-_39229532 0.40 ENST00000378803.5
ENST00000395035.3
cyclin dependent kinase like 4
chr20_+_37383648 0.38 ENST00000373567.6
SRC proto-oncogene, non-receptor tyrosine kinase
chr19_-_53129672 0.38 ENST00000595174.5
zinc finger protein 415
chr20_+_34194569 0.36 ENST00000568305.5
agouti signaling protein
chr16_+_75656195 0.36 ENST00000564671.2
TERF2 interacting protein
chr7_+_49773632 0.36 ENST00000340652.5
von Willebrand factor C domain containing 2
chr8_-_39838250 0.36 ENST00000622267.1
ADAM metallopeptidase domain 2
chrX_-_63755032 0.35 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr18_+_34709356 0.35 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chrX_-_10620534 0.34 ENST00000317552.9
midline 1
chr1_-_84690735 0.34 ENST00000422026.1
SSX family member 2 interacting protein
chrX_+_103628959 0.34 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr2_-_231125032 0.34 ENST00000258400.4
5-hydroxytryptamine receptor 2B
chr15_+_40240522 0.34 ENST00000558878.6
ENST00000558183.6
p21 (RAC1) activated kinase 6
chr19_-_22784091 0.32 ENST00000596209.4
zinc finger protein 99
chr5_+_23443526 0.31 ENST00000635252.1
PR/SET domain 9
chr19_-_53129659 0.31 ENST00000601215.5
zinc finger protein 415
chr3_-_193554885 0.31 ENST00000342695.9
ATPase 13A4
chr18_-_24311495 0.30 ENST00000357041.8
oxysterol binding protein like 1A
chr14_-_102235402 0.30 ENST00000561150.5
ENST00000522867.1
MOK protein kinase
chr3_-_179266971 0.29 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr18_+_58362467 0.29 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr12_-_86256376 0.28 ENST00000552435.6
MGAT4 family member C
chr6_+_157716037 0.28 ENST00000614800.4
sorting nexin 9
chr1_+_50103903 0.28 ENST00000371827.5
ELAV like RNA binding protein 4
chr20_+_45629717 0.28 ENST00000372643.4
WAP four-disulfide core domain 10A
chr22_-_28741783 0.28 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr1_+_209686173 0.27 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr20_+_38304149 0.27 ENST00000262865.9
ENST00000642449.2
bactericidal permeability increasing protein
chr1_-_157099798 0.26 ENST00000454449.3
ETS variant transcription factor 3 like
chr1_+_170663134 0.26 ENST00000367760.7
paired related homeobox 1
chr5_-_139482741 0.24 ENST00000330794.9
stimulator of interferon response cGAMP interactor 1
chr14_-_68794597 0.24 ENST00000336440.3
ZFP36 ring finger protein like 1
chr1_+_103750406 0.24 ENST00000370079.3
amylase alpha 1C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.9 3.6 GO:0030185 nitric oxide transport(GO:0030185)
0.5 1.6 GO:0018963 phthalate metabolic process(GO:0018963)
0.4 1.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.4 1.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 3.0 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.0 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 1.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 1.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.3 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.2 1.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.7 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.3 GO:0010044 response to aluminum ion(GO:0010044)
0.1 2.8 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.9 GO:0018032 protein amidation(GO:0018032)
0.1 0.5 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.8 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 2.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.7 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.9 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.3 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 1.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.1 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 2.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 2.1 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.2 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.8 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.5 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.9 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 1.1 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.8 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 1.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 2.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.5 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 0.8 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 2.0 GO:0042587 glycogen granule(GO:0042587)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 1.5 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 3.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0071547 piP-body(GO:0071547)
0.1 1.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 21.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 1.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0030492 hemoglobin binding(GO:0030492)
0.4 2.0 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 2.0 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.3 2.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 1.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 0.8 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 0.7 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 3.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 0.8 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 3.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 10.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0030305 heparanase activity(GO:0030305)
0.1 0.9 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 2.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 21.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 5.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.4 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 5.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 3.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling