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avrg: Illumina Body Map 2 (GSE30611)

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Results for MEF2C

Z-value: 7.05

Motif logo

Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
ENSG00000081189.16 MEF2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg38_v1_chr5_-_88824334_888243620.354.7e-02Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_110920568 72.62 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr17_+_39665340 66.13 ENST00000578283.1
ENST00000309889.3
titin-cap
chr11_-_19201976 63.57 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr22_-_35617321 56.29 ENST00000397326.7
ENST00000442617.1
myoglobin
chr3_-_39192584 54.63 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr10_-_73651013 54.04 ENST00000372873.8
synaptopodin 2 like
chr6_-_123636923 51.72 ENST00000334268.9
triadin
chr16_-_31428325 45.09 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr5_+_191477 42.50 ENST00000328278.4
leucine rich repeat containing 14B
chr7_-_113919000 40.21 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr11_-_19202004 40.00 ENST00000648719.1
cysteine and glycine rich protein 3
chr22_+_25742141 39.38 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr2_+_169509693 38.63 ENST00000284669.2
kelch like family member 41
chr12_-_110920710 38.47 ENST00000546404.1
myosin light chain 2
chr3_-_52452828 38.33 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr10_-_73655984 37.51 ENST00000394810.3
synaptopodin 2 like
chr1_-_26067622 37.26 ENST00000374272.4
tripartite motif containing 63
chr6_-_123636906 37.12 ENST00000628709.2
triadin
chr10_+_49299159 37.01 ENST00000374144.8
chromosome 10 open reading frame 71
chr2_+_167187283 36.61 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr8_-_123653794 36.57 ENST00000684634.1
kelch like family member 38
chr6_-_123636966 36.29 ENST00000542443.5
triadin
chr10_-_113664033 35.80 ENST00000359988.4
ENST00000369360.7
ENST00000360478.7
ENST00000369358.8
nebulin related anchoring protein
chr6_-_123636997 35.56 ENST00000546248.5
triadin
chr17_+_4951758 34.95 ENST00000518175.1
enolase 3
chr6_-_123636979 34.86 ENST00000662930.1
triadin
chr1_-_146021724 33.53 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr2_+_88067818 33.37 ENST00000444564.2
ENST00000419482.7
SET and MYND domain containing 1
chr4_+_119135825 33.03 ENST00000307128.6
myozenin 2
chr1_+_228208054 32.88 ENST00000284548.16
ENST00000422127.5
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr12_+_101594849 32.04 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr14_-_23408265 31.68 ENST00000405093.9
myosin heavy chain 6
chr1_+_228208024 31.27 ENST00000570156.7
ENST00000680850.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr2_+_167187364 31.01 ENST00000672671.1
xin actin binding repeat containing 2
chr11_+_1838970 29.75 ENST00000381911.6
troponin I2, fast skeletal type
chr5_+_54455661 28.22 ENST00000302005.3
heat shock protein family B (small) member 3
chr2_-_210303608 27.67 ENST00000341685.8
myosin light chain 1
chr3_-_46863435 27.28 ENST00000395869.5
ENST00000653454.1
ENST00000292327.6
myosin light chain 3
chr11_+_1919694 26.87 ENST00000278317.11
ENST00000453458.5
ENST00000381557.6
ENST00000381579.7
ENST00000381589.7
ENST00000381563.8
ENST00000344578.8
ENST00000381558.6
troponin T3, fast skeletal type
chr7_-_44065541 26.33 ENST00000297283.4
phosphoglycerate mutase 2
chr2_+_238138661 26.18 ENST00000409223.2
kelch like family member 30
chr11_-_64759967 25.96 ENST00000377432.7
ENST00000164139.4
glycogen phosphorylase, muscle associated
chr10_+_86668501 25.91 ENST00000623056.4
ENST00000263066.11
ENST00000429277.7
ENST00000361373.9
ENST00000372066.8
ENST00000372056.8
ENST00000623007.3
LIM domain binding 3
chr1_-_201421718 25.82 ENST00000367312.5
ENST00000555340.6
ENST00000361379.9
ENST00000622580.4
troponin I1, slow skeletal type
chr8_+_2045037 24.96 ENST00000262113.9
myomesin 2
chr11_+_1839602 24.91 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr2_+_88067849 24.15 ENST00000438570.1
SET and MYND domain containing 1
chr1_+_160190567 23.45 ENST00000368078.8
calsequestrin 1
chr1_-_31373067 23.10 ENST00000373713.7
fatty acid binding protein 3
chr18_-_3219849 22.66 ENST00000261606.11
myomesin 1
chr8_+_2045058 22.41 ENST00000523438.1
myomesin 2
chr18_-_3219961 21.93 ENST00000356443.9
myomesin 1
chr1_-_115768702 21.71 ENST00000261448.6
calsequestrin 2
chr17_-_9791586 20.87 ENST00000571134.2
dehydrogenase/reductase 7C
chr17_-_29622893 20.65 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr17_-_29140373 20.58 ENST00000533420.3
myosin XVIIIA
chr11_+_1839452 20.51 ENST00000381906.5
troponin I2, fast skeletal type
chr1_-_982086 20.06 ENST00000341290.6
PPARGC1 and ESRR induced regulator, muscle 1
chr12_+_101568350 19.58 ENST00000550514.5
myosin binding protein C1
chrX_+_136197020 19.36 ENST00000370676.7
four and a half LIM domains 1
chr1_-_24112125 19.14 ENST00000374434.4
myomesin 3
chr3_+_179653032 18.35 ENST00000680587.1
ENST00000681064.1
ENST00000263966.8
ENST00000681358.1
ENST00000679749.1
ubiquitin specific peptidase 13
chr17_+_7281711 18.01 ENST00000317370.13
ENST00000571308.5
solute carrier family 2 member 4
chr12_-_57251169 17.62 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr17_-_29622732 17.36 ENST00000683819.1
ENST00000492276.7
coronin 6
chr3_+_179653129 16.77 ENST00000680008.1
ubiquitin specific peptidase 13
chr6_-_46015812 16.52 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chrX_+_136197039 16.18 ENST00000370683.6
four and a half LIM domains 1
chr14_+_104724221 15.95 ENST00000330877.7
adenylosuccinate synthase 1
chr8_-_33599935 15.83 ENST00000523956.1
ENST00000256261.9
dual specificity phosphatase 26
chr5_-_16508990 15.80 ENST00000399793.6
reticulophagy regulator 1
chr6_-_75493629 15.60 ENST00000393004.6
filamin A interacting protein 1
chr3_+_42685535 15.59 ENST00000287777.5
kelch like family member 40
chr5_-_16508812 15.32 ENST00000683414.1
reticulophagy regulator 1
chrX_-_15314543 15.27 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr22_-_50578417 15.14 ENST00000312108.12
ENST00000395650.6
carnitine palmitoyltransferase 1B
chr3_+_136022734 15.11 ENST00000334546.6
protein phosphatase 2 regulatory subunit B''alpha
chr11_-_47352693 15.09 ENST00000256993.8
ENST00000399249.6
ENST00000545968.6
myosin binding protein C3
chr5_-_16508788 15.00 ENST00000682142.1
reticulophagy regulator 1
chr1_-_100178215 14.82 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
leucine rich repeat containing 39
chr16_+_31214088 14.81 ENST00000613872.1
tripartite motif containing 72
chr14_-_93955577 14.56 ENST00000555507.5
ankyrin repeat and SOCS box containing 2
chrX_+_136196750 14.55 ENST00000539015.5
four and a half LIM domains 1
chr14_+_24132050 14.37 ENST00000559294.1
fat storage inducing transmembrane protein 1
chr19_-_49072699 14.32 ENST00000221444.2
potassium voltage-gated channel subfamily A member 7
chr5_-_16508858 14.30 ENST00000684456.1
reticulophagy regulator 1
chr6_-_46015607 14.30 ENST00000644878.1
ENST00000644324.1
ENST00000672327.1
chloride intracellular channel 5
chr16_+_31214111 14.22 ENST00000322122.8
tripartite motif containing 72
chr15_-_82806054 14.05 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr5_-_16508951 13.83 ENST00000682628.1
reticulophagy regulator 1
chr2_+_102761963 13.67 ENST00000640575.2
ENST00000412401.3
transmembrane protein 182
chr7_-_151187212 13.67 ENST00000420175.3
ENST00000275838.5
ankyrin repeat and SOCS box containing 10
chr19_+_3933581 13.34 ENST00000593949.1
nicotinamide riboside kinase 2
chrX_-_64230600 13.21 ENST00000362002.3
ankyrin repeat and SOCS box containing 12
chr4_-_185775890 12.72 ENST00000437304.6
sorbin and SH3 domain containing 2
chr12_+_109131350 12.67 ENST00000539864.1
acetyl-CoA carboxylase beta
chr15_+_42359454 12.61 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
calpain 3
chr7_+_80602150 12.19 ENST00000309881.11
CD36 molecule
chr17_+_67044530 12.19 ENST00000226021.5
calcium voltage-gated channel auxiliary subunit gamma 1
chr7_-_82443715 12.10 ENST00000356253.9
ENST00000423588.1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chrX_+_153781033 11.83 ENST00000370104.5
ENST00000370108.7
ENST00000370101.8
ENST00000430541.5
ENST00000370100.5
SRSF protein kinase 3
chr2_+_219434825 11.58 ENST00000312358.12
striated muscle enriched protein kinase
chr7_+_80602200 11.39 ENST00000534394.5
CD36 molecule
chr7_-_82443766 11.14 ENST00000356860.8
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr14_-_93955258 11.11 ENST00000556062.5
ankyrin repeat and SOCS box containing 2
chr8_+_141416078 11.05 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr10_-_29634964 11.00 ENST00000375398.6
ENST00000355867.8
supervillin
chr8_+_141416141 10.72 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr15_+_42359577 10.61 ENST00000357568.8
calpain 3
chr8_+_141417902 10.52 ENST00000681443.1
protein tyrosine phosphatase 4A3
chr1_-_201377652 10.47 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
troponin T2, cardiac type
chr1_-_114695533 10.39 ENST00000520113.7
adenosine monophosphate deaminase 1
chr4_-_185775411 10.17 ENST00000445115.5
ENST00000451701.5
sorbin and SH3 domain containing 2
chr10_-_60140515 10.13 ENST00000486349.2
ankyrin 3
chr1_-_114695613 10.12 ENST00000369538.4
adenosine monophosphate deaminase 1
chr2_-_178672418 10.11 ENST00000448510.2
titin
chr12_-_48999363 10.11 ENST00000421952.3
dendrin
chr7_-_151187772 10.08 ENST00000377867.7
ankyrin repeat and SOCS box containing 10
chr10_-_75073627 10.00 ENST00000338487.6
dual specificity phosphatase 29
chr9_-_33402551 9.94 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
aquaporin 7
chr3_+_8501807 9.76 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr4_+_94451857 9.71 ENST00000318007.9
ENST00000380180.7
ENST00000437932.5
ENST00000615540.4
ENST00000359265.8
ENST00000512274.1
ENST00000503974.5
ENST00000504489.3
ENST00000317968.9
ENST00000542407.5
PDZ and LIM domain 5
chr4_+_113145608 9.66 ENST00000511380.1
ankyrin 2
chr11_+_3645105 9.61 ENST00000250693.2
ADP-ribosyltransferase 1
chr7_+_95485934 9.59 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr4_-_185775432 9.46 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
sorbin and SH3 domain containing 2
chr4_+_41360759 9.41 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr16_+_7332744 9.37 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr13_+_75804169 9.14 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr15_+_65076744 8.86 ENST00000432196.5
kelch repeat and BTB domain containing 13
chr3_+_127915226 8.73 ENST00000405109.5
kelch repeat and BTB domain containing 12
chr9_+_97501622 8.70 ENST00000259365.9
tropomodulin 1
chr3_-_192727500 8.62 ENST00000430714.5
ENST00000418610.1
ENST00000445105.7
ENST00000684728.1
ENST00000448795.5
ENST00000683935.1
ENST00000684282.1
ENST00000683451.1
fibroblast growth factor 12
chr6_-_75493773 8.55 ENST00000237172.12
filamin A interacting protein 1
chr5_+_96742183 8.45 ENST00000509259.5
ENST00000503828.5
calpastatin
chr9_-_33402449 8.27 ENST00000377425.8
aquaporin 7
chr3_+_159852933 8.18 ENST00000482804.1
schwannomin interacting protein 1
chr2_-_179049986 8.18 ENST00000409284.1
ENST00000443758.6
ENST00000446116.5
coiled-coil domain containing 141
chr4_+_109912877 8.18 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr4_-_185775484 7.85 ENST00000444771.5
sorbin and SH3 domain containing 2
chr13_+_75804270 7.75 ENST00000447038.5
LIM domain 7
chr7_-_56092932 7.72 ENST00000446428.5
ENST00000432123.5
ENST00000297373.7
phosphorylase kinase catalytic subunit gamma 1
chr16_+_30064142 7.64 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr16_+_30064731 7.57 ENST00000563987.5
aldolase, fructose-bisphosphate A
chr14_-_103942516 7.43 ENST00000557640.2
RD3 like
chr3_+_8501846 7.40 ENST00000454244.4
LIM and cysteine rich domains 1
chr10_-_67696115 7.29 ENST00000433211.7
catenin alpha 3
chr16_+_30064274 7.29 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr13_+_75760431 7.27 ENST00000321797.12
LIM domain 7
chr12_-_69610898 7.20 ENST00000361484.5
leucine rich repeat containing 10
chr20_+_34977625 7.11 ENST00000618182.6
myosin heavy chain 7B
chr1_-_205813177 7.11 ENST00000367137.4
solute carrier family 41 member 1
chr3_+_127915469 7.08 ENST00000407609.7
kelch repeat and BTB domain containing 12
chrX_+_153781001 7.03 ENST00000393786.7
SRSF protein kinase 3
chr4_-_185775271 6.97 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr13_+_75804221 6.95 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr7_+_76302665 6.87 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr10_-_60141004 6.65 ENST00000355288.6
ankyrin 3
chr13_+_75760659 6.57 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr9_+_68356603 6.56 ENST00000396396.6
phosphoglucomutase 5
chr16_+_30064462 6.48 ENST00000412304.6
aldolase, fructose-bisphosphate A
chr19_+_35138993 6.47 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr4_+_168497113 6.35 ENST00000511948.1
palladin, cytoskeletal associated protein
chr3_+_69763726 6.21 ENST00000448226.9
melanocyte inducing transcription factor
chr18_+_3252208 5.96 ENST00000578562.6
myosin light chain 12A
chr7_-_56092974 5.90 ENST00000452681.6
ENST00000537360.5
phosphorylase kinase catalytic subunit gamma 1
chr15_-_70702273 5.88 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr14_-_23183641 5.88 ENST00000469263.5
ENST00000525062.1
ENST00000316902.12
ENST00000524758.1
solute carrier family 7 member 8
chr9_+_68356899 5.77 ENST00000396392.5
phosphoglucomutase 5
chrM_+_5824 5.73 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr17_+_44170695 5.58 ENST00000293414.6
ankyrin repeat and SOCS box containing 16
chr4_-_23890070 5.57 ENST00000617484.4
ENST00000612355.1
PPARG coactivator 1 alpha
chr2_+_181986015 5.54 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr19_+_35138778 5.45 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr19_+_35139440 5.35 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr8_-_17676484 5.21 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr4_-_185775376 5.20 ENST00000456596.5
ENST00000414724.5
sorbin and SH3 domain containing 2
chr16_+_6019016 5.03 ENST00000550418.6
RNA binding fox-1 homolog 1
chr4_-_23890035 5.02 ENST00000507380.1
ENST00000264867.7
PPARG coactivator 1 alpha
chr18_+_3252267 4.98 ENST00000536605.1
ENST00000580887.5
myosin light chain 12A
chr4_+_41612892 4.98 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr19_+_6739650 4.88 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
thyroid hormone receptor interactor 10
chr16_+_7332839 4.87 ENST00000355637.9
RNA binding fox-1 homolog 1
chrX_-_15384402 4.81 ENST00000297904.4
vascular endothelial growth factor D
chr1_-_178869272 4.81 ENST00000444255.1
angiopoietin like 1
chr3_+_35642159 4.75 ENST00000187397.8
cAMP regulated phosphoprotein 21
chr10_+_61901678 4.48 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr7_+_143316105 4.37 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr10_-_14838003 4.29 ENST00000465530.2
cerebral dopamine neurotrophic factor
chr1_+_170664121 4.19 ENST00000239461.11
paired related homeobox 1
chr4_+_41612702 4.10 ENST00000509277.5
LIM and calponin homology domains 1
chr6_+_44226628 4.02 ENST00000647460.1
ENST00000646582.1
solute carrier family 29 member 1 (Augustine blood group)
chr1_-_209802149 4.02 ENST00000456314.1
interferon regulatory factor 6
chr8_-_23854796 3.82 ENST00000290271.7
stanniocalcin 1
chr16_+_6019071 3.79 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr1_+_63523490 3.74 ENST00000371088.5
EF-hand calcium binding domain 7
chr15_-_92809798 3.73 ENST00000557398.2
family with sequence similarity 174 member B
chr17_-_44111253 3.70 ENST00000591714.5
histone deacetylase 5
chr12_-_21941402 3.64 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ATP binding cassette subfamily C member 9
chr15_+_63597378 3.59 ENST00000638704.2
ENST00000534939.2
F-box and leucine rich repeat protein 22

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
39.1 195.5 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
18.0 179.8 GO:0035995 detection of muscle stretch(GO:0035995)
12.2 48.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
11.5 92.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
9.3 74.3 GO:0061709 reticulophagy(GO:0061709)
8.8 35.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
8.5 111.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
8.0 47.8 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
7.2 85.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
6.3 56.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
5.9 23.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
5.4 69.9 GO:0036309 protein localization to M-band(GO:0036309)
4.4 26.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
4.1 20.3 GO:1903028 positive regulation of opsonization(GO:1903028)
4.0 15.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
3.9 23.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.5 31.7 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
3.3 23.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
3.1 21.7 GO:0086029 cellular response to caffeine(GO:0071313) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
2.8 193.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
2.6 15.6 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
2.6 23.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
2.6 38.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
2.5 17.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.4 29.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
2.4 7.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
2.4 18.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
2.2 8.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.9 50.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.9 20.5 GO:0032264 IMP salvage(GO:0032264)
1.8 23.6 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
1.8 12.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.7 17.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
1.7 32.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.6 8.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
1.6 14.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.6 17.2 GO:0015793 glycerol transport(GO:0015793)
1.5 29.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.4 2.9 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.4 57.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
1.3 30.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
1.2 62.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.1 6.9 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.1 6.8 GO:0015862 uridine transport(GO:0015862)
1.0 7.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.9 16.2 GO:0006853 carnitine shuttle(GO:0006853)
0.9 93.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.9 20.1 GO:0014850 response to muscle activity(GO:0014850)
0.8 12.3 GO:0019388 galactose catabolic process(GO:0019388)
0.8 4.9 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.8 39.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.8 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 35.0 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.7 66.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.6 3.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.6 4.8 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.6 23.6 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.6 3.4 GO:0031133 regulation of axon diameter(GO:0031133)
0.6 41.9 GO:0030239 myofibril assembly(GO:0030239)
0.5 48.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.5 17.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 10.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.5 6.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.5 12.6 GO:0003334 keratinocyte development(GO:0003334)
0.4 2.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 3.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4 13.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.4 1.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 18.0 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.4 8.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4 1.7 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.4 37.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.4 25.7 GO:0045445 myoblast differentiation(GO:0045445)
0.3 3.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 4.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 3.9 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.3 0.8 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 35.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.2 2.9 GO:0051013 microtubule severing(GO:0051013)
0.2 4.0 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 18.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 9.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 10.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 4.7 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.2 3.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 111.7 GO:0043687 post-translational protein modification(GO:0043687)
0.1 12.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 5.9 GO:0015695 organic cation transport(GO:0015695)
0.1 1.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 2.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 4.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 4.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 1.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.6 GO:0015692 lead ion transport(GO:0015692)
0.1 16.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.0 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 2.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.8 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.1 1.1 GO:0030502 negative regulation of bone mineralization(GO:0030502) saliva secretion(GO:0046541)
0.1 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 7.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 4.5 GO:0016577 histone demethylation(GO:0016577)
0.1 1.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 2.7 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 16.3 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 66.8 GO:0016567 protein ubiquitination(GO:0016567)
0.1 1.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 2.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 8.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 33.9 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 5.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.0 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 2.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 1.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 2.3 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.2 240.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
14.9 59.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
9.8 118.2 GO:0097512 cardiac myofibril(GO:0097512)
8.4 176.7 GO:0005861 troponin complex(GO:0005861)
6.0 35.8 GO:0005927 muscle tendon junction(GO:0005927)
5.0 35.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
4.7 127.8 GO:0032982 myosin filament(GO:0032982)
4.1 12.3 GO:0005914 spot adherens junction(GO:0005914)
3.5 10.6 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
3.5 204.0 GO:0031430 M band(GO:0031430)
3.2 54.9 GO:0005859 muscle myosin complex(GO:0005859)
3.1 37.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.8 50.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
2.0 18.0 GO:0032593 insulin-responsive compartment(GO:0032593)
1.8 508.5 GO:0030018 Z disc(GO:0030018)
1.7 39.9 GO:0016461 unconventional myosin complex(GO:0016461)
1.4 15.6 GO:0031672 A band(GO:0031672)
1.4 23.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.2 13.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.0 10.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.9 74.3 GO:0005801 cis-Golgi network(GO:0005801)
0.8 89.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8 53.9 GO:0031941 filamentous actin(GO:0031941)
0.7 17.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 7.3 GO:0005916 fascia adherens(GO:0005916)
0.6 28.1 GO:0016459 myosin complex(GO:0016459)
0.5 33.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.5 11.0 GO:0036449 microtubule minus-end(GO:0036449)
0.5 8.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.5 2.9 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.4 10.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 16.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 35.1 GO:0034707 chloride channel complex(GO:0034707)
0.3 15.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 11.7 GO:0016528 sarcoplasm(GO:0016528)
0.2 2.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 7.2 GO:0030017 sarcomere(GO:0030017)
0.2 4.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 10.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 65.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 2.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 23.3 GO:0042383 sarcolemma(GO:0042383)
0.1 4.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.5 GO:0016589 NURF complex(GO:0016589)
0.1 7.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 62.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 3.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 14.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 15.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 6.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 22.9 GO:0005769 early endosome(GO:0005769)
0.0 3.0 GO:0030027 lamellipodium(GO:0030027)
0.0 4.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 4.4 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 8.2 GO:0005925 focal adhesion(GO:0005925)
0.0 2.0 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 99.2 GO:0051373 FATZ binding(GO:0051373)
9.5 113.7 GO:0031433 telethonin binding(GO:0031433)
9.3 37.3 GO:0030172 troponin C binding(GO:0030172)
8.1 113.5 GO:0031014 troponin T binding(GO:0031014)
7.7 23.2 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
7.7 23.1 GO:0070538 oleic acid binding(GO:0070538)
7.4 252.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
6.9 158.9 GO:0032036 myosin heavy chain binding(GO:0032036)
6.5 26.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
5.3 26.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
5.2 124.6 GO:0031432 titin binding(GO:0031432)
4.4 35.1 GO:1904288 BAT3 complex binding(GO:1904288)
4.0 31.7 GO:0017018 myosin phosphatase activity(GO:0017018)
3.6 32.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
3.3 13.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
2.9 35.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.6 15.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.6 18.2 GO:0015254 glycerol channel activity(GO:0015254)
2.3 52.4 GO:0005344 oxygen transporter activity(GO:0005344)
2.2 29.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.0 23.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
1.9 15.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.8 12.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.8 10.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.7 6.9 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
1.6 76.2 GO:0051393 alpha-actinin binding(GO:0051393)
1.5 12.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.5 50.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.2 13.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.2 52.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.1 9.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.8 18.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.8 7.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.7 233.9 GO:0044325 ion channel binding(GO:0044325)
0.7 19.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.6 8.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6 57.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.6 9.7 GO:0042805 actinin binding(GO:0042805)
0.6 2.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.6 30.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.5 29.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.5 9.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 2.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 5.9 GO:0019534 toxin transporter activity(GO:0019534)
0.4 9.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.4 8.7 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.7 GO:0031013 troponin I binding(GO:0031013)
0.4 27.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 4.0 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 1.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.3 246.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 5.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 274.1 GO:0003779 actin binding(GO:0003779)
0.3 7.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 2.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 4.9 GO:0070411 I-SMAD binding(GO:0070411)
0.2 6.2 GO:0044548 S100 protein binding(GO:0044548)
0.2 19.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 2.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 6.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.7 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.2 10.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 4.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 2.9 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 15.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 6.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.7 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 4.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.4 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 19.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 3.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 4.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 111.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 35.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 64.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 21.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 10.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 6.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 25.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 15.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 4.3 PID FGF PATHWAY FGF signaling pathway
0.0 7.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 473.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.3 39.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.2 84.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.0 17.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.8 20.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 27.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.6 18.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 63.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.4 20.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 8.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 18.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 6.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 132.5 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.2 6.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 2.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 14.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 7.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 6.8 REACTOME DEFENSINS Genes involved in Defensins
0.1 6.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 6.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 5.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 4.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation