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avrg: Illumina Body Map 2 (GSE30611)

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Results for NFKB2

Z-value: 2.09

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Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
ENSG00000077150.20 NFKB2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg38_v1_chr10_+_102394488_1023945400.584.9e-04Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_35880350 7.99 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr19_+_41877267 5.97 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr15_-_88895511 5.74 ENST00000562281.1
ENST00000359595.8
ENST00000562889.5
hyaluronan and proteoglycan link protein 3
chr20_+_45174894 5.72 ENST00000243924.4
peptidase inhibitor 3
chr3_+_53161241 5.54 ENST00000477794.2
ENST00000650739.1
protein kinase C delta
chr1_-_27635176 5.33 ENST00000374005.8
FGR proto-oncogene, Src family tyrosine kinase
chr22_-_37244237 5.17 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr2_-_89010515 4.75 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr2_-_89320146 4.71 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr2_-_88947820 4.69 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_-_89117844 3.99 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr22_+_38957522 3.97 ENST00000618553.1
ENST00000249116.7
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
chr22_-_37244417 3.78 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr1_-_202161575 3.77 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
protein tyrosine phosphatase non-receptor type 7
chr2_+_89913982 3.49 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr3_+_53161120 3.40 ENST00000394729.6
ENST00000330452.8
ENST00000652449.1
protein kinase C delta
chr6_+_32637396 3.37 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr19_+_35449584 3.30 ENST00000246549.2
free fatty acid receptor 2
chr19_+_859654 3.30 ENST00000592860.2
ENST00000327726.11
complement factor D
chr19_+_48321454 3.30 ENST00000599704.5
epithelial membrane protein 3
chr2_-_89040745 3.28 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr6_+_29942523 3.14 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr6_+_32637419 3.13 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr4_-_73998669 3.10 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr14_-_95714114 3.04 ENST00000402399.6
ENST00000555202.1
TCL1 family AKT coactivator A
chr17_+_16415553 3.04 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr16_+_30473946 3.03 ENST00000569725.1
integrin subunit alpha L
chr5_+_136058849 3.00 ENST00000508076.5
transforming growth factor beta induced
chrX_+_65667645 2.96 ENST00000360270.7
moesin
chr19_-_41353904 2.96 ENST00000221930.6
transforming growth factor beta 1
chr1_-_206923183 2.95 ENST00000525793.5
Fc fragment of IgM receptor
chr2_-_196171565 2.92 ENST00000263955.9
serine/threonine kinase 17b
chr1_-_151993822 2.89 ENST00000368811.8
S100 calcium binding protein A10
chr1_-_84997079 2.85 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr2_-_89100352 2.85 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr17_+_74466627 2.80 ENST00000360141.8
ENST00000392625.7
ENST00000310828.9
ENST00000361933.7
CD300a molecule
chr1_-_206923242 2.78 ENST00000529560.1
Fc fragment of IgM receptor
chr19_+_17527250 2.78 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr1_-_183590876 2.72 ENST00000367536.5
neutrophil cytosolic factor 2
chr7_+_142715314 2.70 ENST00000390399.3
T cell receptor beta variable 27
chr14_+_51847145 2.66 ENST00000615906.4
G protein subunit gamma 2
chr17_+_74466386 2.65 ENST00000648095.1
CD300a molecule
chr6_+_31400699 2.62 ENST00000674131.1
ENST00000673647.1
ENST00000673857.1
MHC class I polypeptide-related sequence A
novel transcript
chr12_-_52520371 2.61 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr7_-_38363476 2.60 ENST00000426402.2
T cell receptor gamma variable 2
chr1_-_183590596 2.56 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr6_+_106360668 2.53 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr1_-_186680411 2.52 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr2_+_90159840 2.52 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr1_-_47190013 2.43 ENST00000294338.7
PDZK1 interacting protein 1
chr17_-_5583957 2.37 ENST00000354411.7
ENST00000577119.5
NLR family pyrin domain containing 1
chrX_-_154366334 2.34 ENST00000673639.2
filamin A
chr8_+_23084355 2.33 ENST00000397703.6
ENST00000520607.1
novel transcript
novel protein
chr19_-_4540028 2.26 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chr19_+_45001430 2.24 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr10_+_102394488 2.22 ENST00000369966.8
nuclear factor kappa B subunit 2
chr17_-_3916455 2.21 ENST00000225538.4
purinergic receptor P2X 1
chr19_-_3786254 2.19 ENST00000585778.5
megakaryocyte-associated tyrosine kinase
chr1_-_183635776 2.18 ENST00000359856.11
actin related protein 2/3 complex subunit 5
chr7_+_2519763 2.18 ENST00000222725.10
ENST00000359574.7
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_+_78130759 2.17 ENST00000590426.1
ENST00000318430.10
ENST00000590799.5
ENST00000589691.1
transmembrane channel like 8
chr16_-_28181034 2.14 ENST00000570033.1
exportin 6
chr1_+_23791962 2.14 ENST00000421070.1
lysophospholipase 2
chrX_+_72079756 2.13 ENST00000632230.1
NHS like 2
chr10_-_124092390 2.13 ENST00000628426.1
carbohydrate sulfotransferase 15
chr22_+_25564818 2.11 ENST00000619906.4
G protein-coupled receptor kinase 3
chr10_-_124092445 2.10 ENST00000346248.7
carbohydrate sulfotransferase 15
chr14_+_51847116 2.09 ENST00000553560.5
G protein subunit gamma 2
chr3_+_53161501 2.08 ENST00000487897.5
protein kinase C delta
chr5_+_35852695 2.02 ENST00000508941.5
interleukin 7 receptor
chr22_+_36922040 2.01 ENST00000406230.5
colony stimulating factor 2 receptor subunit beta
chr8_-_65842051 2.01 ENST00000401827.8
phosphodiesterase 7A
chr12_+_6946468 1.99 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr19_+_53867874 1.99 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr14_+_92323154 1.98 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr12_+_8509460 1.98 ENST00000382064.6
C-type lectin domain family 4 member D
chr15_+_76995118 1.98 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr17_+_42288464 1.97 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr2_-_88992903 1.93 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_-_22829779 1.89 ENST00000488800.5
solute carrier family 7 member 7
chr16_+_81444799 1.88 ENST00000537098.8
c-Maf inducing protein
chr3_-_13420307 1.88 ENST00000254508.7
nucleoporin 210
chr11_+_34438900 1.86 ENST00000241052.5
catalase
chr8_+_22579100 1.84 ENST00000452226.5
ENST00000397760.8
PDZ and LIM domain 2
chr16_-_4416621 1.84 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chr6_+_143678048 1.83 ENST00000542769.5
ENST00000397980.3
phosphatase and actin regulator 2
chrX_+_49171889 1.82 ENST00000376327.6
proteolipid protein 2
chrX_+_49171918 1.79 ENST00000376322.7
proteolipid protein 2
chr6_+_143677935 1.77 ENST00000440869.6
ENST00000367582.7
ENST00000451827.6
phosphatase and actin regulator 2
chr2_+_218217131 1.75 ENST00000420104.5
ENST00000315717.10
ENST00000295685.14
actin related protein 2/3 complex subunit 2
chr16_+_31527876 1.74 ENST00000302312.9
ENST00000564707.1
alpha hemoglobin stabilizing protein
chr5_+_131264043 1.73 ENST00000505065.2
ENST00000503291.5
ENST00000360515.7
CDC42 small effector 2
chr19_-_47231191 1.72 ENST00000439096.3
BCL2 binding component 3
chr19_-_3786363 1.71 ENST00000310132.11
megakaryocyte-associated tyrosine kinase
chr15_+_91853690 1.70 ENST00000318445.11
solute carrier organic anion transporter family member 3A1
chr15_-_64356074 1.68 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
casein kinase 1 gamma 1
chr16_-_88811897 1.68 ENST00000569616.1
ENST00000563655.5
ENST00000567713.5
ENST00000426324.6
ENST00000378364.8
adenine phosphoribosyltransferase
chr2_+_218880844 1.67 ENST00000258411.8
Wnt family member 10A
chr17_+_42288429 1.66 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr16_-_381935 1.65 ENST00000431232.7
ENST00000250930.7
post-glycosylphosphatidylinositol attachment to proteins 6
chr4_+_73869385 1.64 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr1_-_183635659 1.63 ENST00000367534.5
ENST00000294742.6
actin related protein 2/3 complex subunit 5
chr8_-_6938301 1.63 ENST00000297435.3
defensin alpha 4
chr3_-_39153512 1.61 ENST00000273153.10
cysteine and serine rich nuclear protein 1
chr1_-_155911365 1.61 ENST00000651833.1
ENST00000539040.5
ENST00000651853.1
Ras like without CAAX 1
chr7_-_5423543 1.60 ENST00000399537.8
trinucleotide repeat containing 18
chr8_+_22579139 1.60 ENST00000397761.6
PDZ and LIM domain 2
chr1_+_111227699 1.60 ENST00000369748.9
chitinase 3 like 2
chr1_+_2555639 1.60 ENST00000426449.5
ENST00000434817.5
ENST00000435221.6
TNF receptor superfamily member 14
chr2_+_201183120 1.59 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr9_+_131228109 1.58 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
nucleoporin 214
chr1_-_36323593 1.58 ENST00000490466.2
eva-1 homolog B
chr1_+_2555961 1.57 ENST00000451778.5
TNF receptor superfamily member 14
chr1_-_202160577 1.56 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
protein tyrosine phosphatase non-receptor type 7
chr19_+_17527232 1.56 ENST00000601861.5
niban apoptosis regulator 3
chr1_+_2556361 1.55 ENST00000355716.5
TNF receptor superfamily member 14
chr2_-_108989206 1.54 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
ectodysplasin A receptor
chr6_+_31572279 1.52 ENST00000418386.3
lymphotoxin alpha
chr9_+_128149447 1.51 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr15_+_84748554 1.51 ENST00000560079.7
zinc finger protein 592
chr2_+_10043524 1.49 ENST00000305883.6
Kruppel like factor 11
chr16_+_50742110 1.47 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr5_+_131264008 1.47 ENST00000395246.5
CDC42 small effector 2
chr7_-_5423826 1.46 ENST00000430969.6
trinucleotide repeat containing 18
chr1_+_111227610 1.46 ENST00000369744.6
chitinase 3 like 2
chr5_-_151087131 1.46 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNFAIP3 interacting protein 1
chr5_-_98928992 1.44 ENST00000614616.5
chromodomain helicase DNA binding protein 1
chr16_-_88856909 1.44 ENST00000569433.1
ENST00000268695.10
ENST00000568311.1
galactosamine (N-acetyl)-6-sulfatase
chr8_+_22578735 1.43 ENST00000339162.11
ENST00000308354.11
PDZ and LIM domain 2
chr15_+_91853819 1.43 ENST00000424469.2
solute carrier organic anion transporter family member 3A1
chr12_-_54419259 1.41 ENST00000293379.9
integrin subunit alpha 5
chr1_-_202159977 1.41 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr14_-_91867529 1.40 ENST00000435962.7
tandem C2 domains, nuclear
chr16_-_74700845 1.39 ENST00000308807.12
ENST00000573267.1
mixed lineage kinase domain like pseudokinase
chr22_+_35400115 1.39 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
minichromosome maintenance complex component 5
chr4_-_74038681 1.39 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr14_-_50831046 1.38 ENST00000476352.5
ENST00000324330.13
ENST00000382041.7
ENST00000453401.6
ENST00000530997.7
ninein
chr16_-_67247460 1.37 ENST00000258201.9
formin homology 2 domain containing 1
chr11_+_67583742 1.36 ENST00000398603.6
glutathione S-transferase pi 1
chr16_-_4416564 1.34 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chr19_+_18433234 1.34 ENST00000599699.2
single stranded DNA binding protein 4
chr11_+_72814380 1.34 ENST00000534905.5
ENST00000321297.10
ENST00000540567.1
autophagy related 16 like 2
chr6_+_14117764 1.34 ENST00000379153.4
CD83 molecule
chr6_+_18155329 1.33 ENST00000546309.6
lysine demethylase 1B
chr9_+_79572715 1.33 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chr19_+_3136026 1.33 ENST00000262958.4
G protein subunit alpha 15
chr20_-_4815100 1.33 ENST00000379376.2
Ras association domain family member 2
chr1_-_204467216 1.33 ENST00000367184.2
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr14_+_24136152 1.32 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr14_-_24146596 1.30 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr9_+_79572572 1.30 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr19_-_10568968 1.29 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chr14_-_50830641 1.29 ENST00000453196.6
ENST00000496749.1
ninein
chr6_-_10838503 1.28 ENST00000536370.6
ENST00000474039.5
ENST00000354489.7
ENST00000676116.1
male germ cell associated kinase
chr15_-_64356047 1.28 ENST00000634654.1
casein kinase 1 gamma 1
chr14_-_50830479 1.27 ENST00000382043.8
ninein
chr17_-_18257264 1.26 ENST00000581349.5
ENST00000473425.2
FLII actin remodeling protein
chr6_+_18155399 1.26 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chr16_+_50742037 1.26 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr17_-_55421853 1.24 ENST00000571578.1
monocyte to macrophage differentiation associated
chr10_-_6062290 1.24 ENST00000256876.10
ENST00000379954.5
interleukin 2 receptor subunit alpha
chr8_-_100721851 1.24 ENST00000522658.6
poly(A) binding protein cytoplasmic 1
chr8_-_100721942 1.24 ENST00000522387.5
poly(A) binding protein cytoplasmic 1
chr1_-_155911340 1.23 ENST00000368323.8
Ras like without CAAX 1
chr14_+_22086401 1.23 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr8_-_100722036 1.23 ENST00000518196.5
ENST00000519004.5
ENST00000519363.1
ENST00000318607.10
ENST00000520142.2
poly(A) binding protein cytoplasmic 1
chr8_-_100722174 1.23 ENST00000677380.1
ENST00000677478.1
poly(A) binding protein cytoplasmic 1
chr5_+_177303768 1.23 ENST00000303204.9
ENST00000503216.5
PRELI domain containing 1
chr3_+_183253795 1.22 ENST00000460419.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr22_+_25564628 1.21 ENST00000324198.11
G protein-coupled receptor kinase 3
chr1_+_26545833 1.21 ENST00000531382.5
ribosomal protein S6 kinase A1
chr19_-_10569022 1.21 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr5_+_177304571 1.20 ENST00000503853.1
PRELI domain containing 1
chr8_+_22589240 1.19 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr12_+_57522801 1.18 ENST00000355673.8
ENST00000546632.1
ENST00000549623.1
methyl-CpG binding domain protein 6
chr20_-_49713842 1.18 ENST00000371711.4
beta-1,4-galactosyltransferase 5
chr2_-_106160376 1.17 ENST00000479621.5
UDP-glucuronate decarboxylase 1
chr6_-_73523757 1.17 ENST00000455918.2
ENST00000677236.1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_72223918 1.16 ENST00000543234.1
inositol polyphosphate phosphatase like 1
chr8_-_102655707 1.16 ENST00000285407.11
Kruppel like factor 10
chr14_+_95686419 1.16 ENST00000340722.8
TCL1 family AKT coactivator B
chr7_-_140924699 1.15 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr11_+_818906 1.15 ENST00000336615.9
patatin like phospholipase domain containing 2
chr1_+_2556222 1.15 ENST00000409119.5
TNF receptor superfamily member 14
chr1_-_154970735 1.15 ENST00000368445.9
ENST00000448116.7
ENST00000368449.8
SHC adaptor protein 1
chr2_+_60881553 1.14 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr16_+_81779279 1.13 ENST00000564138.6
phospholipase C gamma 2
chr17_-_55421818 1.12 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr11_-_96343170 1.12 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr9_+_97983332 1.11 ENST00000339399.5
acidic nuclear phosphoprotein 32 family member B
chr16_+_28494634 1.11 ENST00000564831.6
ENST00000431282.2
apolipoprotein B receptor
chr7_+_121062765 1.09 ENST00000423795.5
cadherin like and PC-esterase domain containing 1
chr7_+_7968787 1.09 ENST00000223145.10
glucocorticoid induced 1
chr13_-_110561668 1.08 ENST00000267328.5
RAB20, member RAS oncogene family
chr6_-_30556088 1.08 ENST00000433809.1
G protein nucleolar 1 (putative)
chr19_+_38304105 1.08 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr11_+_65182413 1.08 ENST00000531068.5
ENST00000527699.5
ENST00000533909.5
ENST00000527323.5
calpain 1
chr16_+_89560653 1.07 ENST00000563270.5
ENST00000567815.5
ENST00000311528.10
ENST00000452368.7
ENST00000467736.5
ENST00000393099.3
ribosomal protein L13
chr16_+_50742059 1.06 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chrX_-_153926757 1.06 ENST00000461052.5
ENST00000422091.1
Rho GTPase activating protein 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.0 GO:2000752 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
2.0 8.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.8 5.4 GO:1905154 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
1.3 3.9 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
1.1 3.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.9 3.8 GO:1990108 protein linear deubiquitination(GO:1990108)
0.9 2.6 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.8 2.5 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.8 9.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.8 2.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.8 2.3 GO:0035732 nitric oxide storage(GO:0035732)
0.7 3.0 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.7 5.9 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.6 2.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.6 2.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.5 4.0 GO:0070383 DNA cytosine deamination(GO:0070383)
0.5 2.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 2.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 2.2 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.4 3.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 5.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 3.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.4 1.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.4 1.5 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.4 1.9 GO:0010193 response to ozone(GO:0010193) response to L-ascorbic acid(GO:0033591)
0.4 2.2 GO:0007386 compartment pattern specification(GO:0007386)
0.3 1.7 GO:0044209 AMP salvage(GO:0044209)
0.3 1.0 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.3 3.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 3.0 GO:0002084 protein depalmitoylation(GO:0002084)
0.3 1.5 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 2.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 2.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 2.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 3.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3 3.5 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.2 1.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.9 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2 2.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.8 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 1.3 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 2.6 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 5.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 7.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 1.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.2 3.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.6 GO:0060309 elastin catabolic process(GO:0060309)
0.2 4.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 1.6 GO:0019732 antifungal humoral response(GO:0019732)
0.2 2.0 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.2 1.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 2.5 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 2.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.6 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 1.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 3.0 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.2 5.5 GO:0007620 copulation(GO:0007620)
0.2 0.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 0.8 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 2.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 1.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.8 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.2 1.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 3.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 3.0 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 23.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 5.3 GO:0045730 respiratory burst(GO:0045730)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.6 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 1.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 4.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.7 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 3.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.4 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.3 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.7 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.9 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 3.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.6 GO:1990523 bone regeneration(GO:1990523)
0.1 1.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 1.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.7 GO:0048733 sebaceous gland development(GO:0048733)
0.1 2.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 1.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 3.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.7 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 1.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 2.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 3.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 1.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0042938 positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.1 3.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 2.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.1 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 1.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286) telomere maintenance via base-excision repair(GO:0097698)
0.1 1.5 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1 0.9 GO:0007512 adult heart development(GO:0007512)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 2.4 GO:0019835 cytolysis(GO:0019835)
0.1 0.3 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 1.4 GO:0007097 nuclear migration(GO:0007097)
0.1 1.3 GO:0051014 actin filament severing(GO:0051014)
0.1 5.1 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.1 2.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 4.9 GO:0006968 cellular defense response(GO:0006968)
0.1 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.9 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0048627 myoblast development(GO:0048627)
0.0 1.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 5.8 GO:0031295 T cell costimulation(GO:0031295)
0.0 5.4 GO:0042100 B cell proliferation(GO:0042100)
0.0 4.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 3.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.5 GO:0060065 uterus development(GO:0060065)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 1.0 GO:0045116 protein neddylation(GO:0045116)
0.0 1.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 1.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.6 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0034349 glial cell apoptotic process(GO:0034349)
0.0 1.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.0 4.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 6.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 3.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.7 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.4 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.8 GO:0097186 amelogenesis(GO:0097186)
0.0 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.7 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.7 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 1.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.9 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.2 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 1.1 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 6.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 3.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.5 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.0 1.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.4 GO:0009791 post-embryonic development(GO:0009791)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0019815 B cell receptor complex(GO:0019815)
0.9 3.6 GO:0008537 proteasome activator complex(GO:0008537)
0.7 2.0 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.6 2.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.6 1.8 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.6 2.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 5.3 GO:0032010 phagolysosome(GO:0032010)
0.5 1.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 2.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.4 4.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 2.1 GO:0045160 myosin I complex(GO:0045160)
0.3 3.0 GO:0032584 growth cone membrane(GO:0032584)
0.3 2.3 GO:0031523 Myb complex(GO:0031523)
0.3 6.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 3.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.3 1.5 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.3 3.1 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.3 1.6 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 0.7 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 0.9 GO:1990879 CST complex(GO:1990879)
0.2 4.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 3.9 GO:0036449 microtubule minus-end(GO:0036449)
0.2 4.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 5.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.9 GO:0042825 TAP complex(GO:0042825)
0.1 0.8 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0072563 endothelial microparticle(GO:0072563)
0.1 1.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 2.8 GO:0097342 ripoptosome(GO:0097342)
0.1 0.6 GO:0032044 DSIF complex(GO:0032044)
0.1 10.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.3 GO:0030057 desmosome(GO:0030057)
0.1 3.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 2.6 GO:0000786 nucleosome(GO:0000786)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 3.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 5.9 GO:0001533 cornified envelope(GO:0001533)
0.1 4.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 1.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 12.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 5.4 GO:0097542 ciliary tip(GO:0097542)
0.1 9.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 6.2 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.4 GO:0032059 bleb(GO:0032059)
0.1 2.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 5.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 7.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 15.9 GO:0072562 blood microparticle(GO:0072562)
0.1 1.5 GO:0010369 chromocenter(GO:0010369)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 3.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.7 GO:0034774 secretory granule lumen(GO:0034774)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 1.6 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 3.4 GO:0005643 nuclear pore(GO:0005643)
0.0 8.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 3.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0044815 DNA packaging complex(GO:0044815)
0.0 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 6.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 2.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 19.7 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0035579 specific granule membrane(GO:0035579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.2 11.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.9 7.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.8 4.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.8 2.3 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.7 2.0 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.6 4.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.6 3.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.6 2.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5 2.5 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.5 3.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 2.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 5.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 7.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 2.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.7 GO:0002060 purine nucleobase binding(GO:0002060)
0.4 2.0 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.4 3.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 2.8 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.4 2.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 6.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 5.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.5 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.4 2.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 1.4 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.4 1.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 2.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 5.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.9 GO:0004096 catalase activity(GO:0004096)
0.3 2.6 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3 1.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 5.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 2.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 3.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.3 3.3 GO:0001727 lipid kinase activity(GO:0001727)
0.2 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 4.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 3.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.7 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 3.5 GO:0004568 chitinase activity(GO:0004568)
0.2 3.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 5.6 GO:0008494 translation activator activity(GO:0008494)
0.2 0.9 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 2.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 3.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 5.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 31.0 GO:0003823 antigen binding(GO:0003823)
0.1 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 1.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.0 GO:0089720 caspase binding(GO:0089720)
0.1 5.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 1.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.5 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.1 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.0 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 2.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 3.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 3.6 GO:0019956 chemokine binding(GO:0019956)
0.1 3.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0070728 leucine binding(GO:0070728)
0.0 2.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 8.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 1.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 10.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 4.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 1.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 5.1 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 2.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 1.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 3.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 18.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 20.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 2.6 PID IL27 PATHWAY IL27-mediated signaling events
0.2 5.7 PID IL5 PATHWAY IL5-mediated signaling events
0.2 7.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 9.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 10.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.1 6.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 6.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 5.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 9.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 7.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 3.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 5.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 3.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.1 PID FOXO PATHWAY FoxO family signaling
0.0 2.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 6.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 3.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 11.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 15.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 9.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 6.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 5.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 5.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 8.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 5.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 6.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 5.5 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1 1.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 6.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 2.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.8 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 3.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 3.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 4.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 5.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 3.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 4.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation