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avrg: Illumina Body Map 2 (GSE30611)

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Results for NKX1-1

Z-value: 0.83

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Transcription factors associated with NKX1-1

Gene Symbol Gene ID Gene Info
NKX1-1
ENSG00000235608.2 NKX1-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX1-1hg38_v1_chr4_-_1406442_1406442-0.421.6e-02Click!

Activity profile of NKX1-1 motif

Sorted Z-values of NKX1-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_16347637 3.33 ENST00000543076.5
ENST00000396210.8
MGST1
microsomal glutathione S-transferase 1
chr12_+_16347665 3.26 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
MGST1
microsomal glutathione S-transferase 1
chr12_+_16347102 3.07 ENST00000536371.5
ENST00000010404.6
MGST1
microsomal glutathione S-transferase 1
chr14_+_32329256 1.32 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr10_+_119029711 1.31 ENST00000425699.3
NANOS1
nanos C2HC-type zinc finger 1
chr14_+_32329341 1.28 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr3_+_186842687 1.22 ENST00000444204.2
ENST00000320741.7
ADIPOQ
adiponectin, C1Q and collagen domain containing
chrX_+_19343893 1.14 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
PDHA1
pyruvate dehydrogenase E1 subunit alpha 1
chr12_+_48105466 1.00 ENST00000549003.5
ENST00000550924.6
PFKM
phosphofructokinase, muscle
chr13_-_109786567 0.94 ENST00000375856.5
IRS2
insulin receptor substrate 2
chr11_-_2885728 0.82 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
CDKN1C
cyclin dependent kinase inhibitor 1C
chr11_+_19712823 0.78 ENST00000396085.6
ENST00000349880.9
NAV2
neuron navigator 2
chr6_-_166627244 0.77 ENST00000265678.9
RPS6KA2
ribosomal protein S6 kinase A2
chr7_+_6009222 0.76 ENST00000400479.6
ENST00000223029.8
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr19_-_14117729 0.72 ENST00000590853.5
ENST00000308677.9
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
chr21_+_33025927 0.56 ENST00000430860.1
ENST00000382357.4
ENST00000333337.3
OLIG2
oligodendrocyte transcription factor 2
chr15_-_78234513 0.54 ENST00000558130.1
ENST00000258873.9
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr6_-_82247697 0.50 ENST00000306270.12
ENST00000610980.4
IBTK
inhibitor of Bruton tyrosine kinase
chr19_+_1261091 0.49 ENST00000588411.5
CIRBP
cold inducible RNA binding protein
chr17_+_47209375 0.48 ENST00000572303.1
MYL4
myosin light chain 4
chr6_-_84763355 0.44 ENST00000606621.1
TBX18
T-box transcription factor 18
chr16_-_10942443 0.44 ENST00000570440.2
ENST00000331808.5
DEXI
Dexi homolog
chr13_-_35476682 0.42 ENST00000379919.6
MAB21L1
mab-21 like 1
chr9_+_34646589 0.41 ENST00000450095.6
GALT
galactose-1-phosphate uridylyltransferase
chr18_+_58221535 0.40 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr9_+_34646654 0.38 ENST00000378842.8
GALT
galactose-1-phosphate uridylyltransferase
chr7_+_26291941 0.38 ENST00000412416.5
SNX10
sorting nexin 10
chrX_+_152831054 0.38 ENST00000370274.8
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr7_-_6009072 0.37 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS2
PMS1 homolog 2, mismatch repair system component
chr17_+_1762814 0.36 ENST00000570731.5
SERPINF1
serpin family F member 1
chr17_+_47209338 0.36 ENST00000393450.5
MYL4
myosin light chain 4
chr11_-_2139382 0.36 ENST00000416167.7
IGF2
insulin like growth factor 2
chr7_-_16420623 0.36 ENST00000676325.1
CRPPA
CDP-L-ribitol pyrophosphorylase A
chr2_+_86720282 0.35 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr1_+_240091866 0.34 ENST00000319653.14
FMN2
formin 2
chr21_-_36542600 0.34 ENST00000399136.5
CLDN14
claudin 14
chr10_+_97446194 0.34 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr8_+_93916849 0.32 ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_4967790 0.30 ENST00000575142.5
ENST00000206020.8
SPAG7
sperm associated antigen 7
chr19_+_9835292 0.30 ENST00000247970.9
ENST00000587625.5
ENST00000588695.5
PIN1
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr9_+_121567057 0.30 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr2_+_62705866 0.30 ENST00000263991.9
EHBP1
EH domain binding protein 1
chr1_-_159862648 0.28 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr3_-_105869387 0.28 ENST00000438603.6
ENST00000443752.2
CBLB
Cbl proto-oncogene B
chr4_-_145180496 0.28 ENST00000447906.8
OTUD4
OTU deubiquitinase 4
chr9_+_34646627 0.28 ENST00000556278.1
ENSG00000258728.1
novel protein (GALT-IL11RA readthrough)
chr4_-_53365976 0.28 ENST00000401642.8
ENST00000388940.8
ENST00000503450.1
SCFD2
sec1 family domain containing 2
chr18_+_36129444 0.28 ENST00000543127.5
ELP2
elongator acetyltransferase complex subunit 2
chr11_-_59615673 0.28 ENST00000263847.6
OSBP
oxysterol binding protein
chr19_+_10252206 0.27 ENST00000253099.11
ENST00000393733.6
ENST00000588502.5
MRPL4
mitochondrial ribosomal protein L4
chr11_-_47176851 0.27 ENST00000629231.2
ENST00000526342.5
ENST00000528444.5
ENST00000530596.5
ENST00000525398.5
ENST00000524782.6
ENST00000527927.5
ENST00000525314.5
ARFGAP2
ADP ribosylation factor GTPase activating protein 2
chr17_-_47189176 0.27 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
CDC27
cell division cycle 27
chr10_+_97446137 0.26 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr12_+_6852115 0.26 ENST00000389231.9
ENST00000229268.13
ENST00000542087.1
USP5
ubiquitin specific peptidase 5
chr15_-_64093746 0.25 ENST00000557835.5
ENST00000380290.7
ENST00000300030.8
ENST00000559950.1
CIAO2A
cytosolic iron-sulfur assembly component 2A
chr2_+_62705644 0.25 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EHBP1
EH domain binding protein 1
chr19_-_4065732 0.24 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr1_-_51330527 0.24 ENST00000439482.6
TTC39A
tetratricopeptide repeat domain 39A
chr6_+_132538290 0.24 ENST00000434551.2
TAAR9
trace amine associated receptor 9
chr19_-_46634685 0.24 ENST00000300873.4
GNG8
G protein subunit gamma 8
chr16_+_590200 0.23 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr12_-_91058016 0.23 ENST00000266719.4
KERA
keratocan
chr2_-_238288600 0.23 ENST00000254657.8
PER2
period circadian regulator 2
chr2_-_166375969 0.22 ENST00000454569.6
ENST00000409672.5
SCN9A
sodium voltage-gated channel alpha subunit 9
chr2_-_46915745 0.22 ENST00000649435.1
ENST00000409105.5
ENST00000319466.9
ENST00000409973.5
ENST00000409913.5
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr11_-_4608138 0.21 ENST00000533021.1
TRIM68
tripartite motif containing 68
chr21_-_31038476 0.21 ENST00000382822.2
KRTAP19-8
keratin associated protein 19-8
chr7_-_6009019 0.20 ENST00000382321.5
ENST00000265849.12
PMS2
PMS1 homolog 2, mismatch repair system component
chr2_+_216659600 0.20 ENST00000456764.1
IGFBP2
insulin like growth factor binding protein 2
chrX_+_155216452 0.20 ENST00000286428.7
VBP1
VHL binding protein 1
chr17_-_59155235 0.20 ENST00000581068.5
SKA2
spindle and kinetochore associated complex subunit 2
chr17_-_10469558 0.20 ENST00000255381.2
MYH4
myosin heavy chain 4
chr11_-_111871530 0.19 ENST00000614444.4
ENST00000616540.5
ALG9
ALG9 alpha-1,2-mannosyltransferase
chr1_-_51330553 0.19 ENST00000680483.1
ENST00000371747.7
TTC39A
tetratricopeptide repeat domain 39A
chr9_+_72577788 0.18 ENST00000645208.2
TMC1
transmembrane channel like 1
chr7_+_26291850 0.18 ENST00000338523.9
ENST00000446848.6
SNX10
sorting nexin 10
chr5_-_116554858 0.18 ENST00000509665.1
SEMA6A
semaphorin 6A
chr2_-_46916020 0.18 ENST00000409800.5
ENST00000409218.5
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr12_-_55296569 0.18 ENST00000358433.3
OR6C6
olfactory receptor family 6 subfamily C member 6
chr7_+_71132123 0.18 ENST00000333538.10
GALNT17
polypeptide N-acetylgalactosaminyltransferase 17
chr13_+_35476740 0.18 ENST00000537702.5
NBEA
neurobeachin
chr2_+_149330506 0.17 ENST00000334166.9
LYPD6
LY6/PLAUR domain containing 6
chr11_+_73272201 0.17 ENST00000393590.3
P2RY6
pyrimidinergic receptor P2Y6
chr1_-_51331315 0.16 ENST00000262676.9
TTC39A
tetratricopeptide repeat domain 39A
chr7_+_26291898 0.16 ENST00000416246.5
SNX10
sorting nexin 10
chr17_-_59155164 0.16 ENST00000583380.5
ENST00000580541.1
ENST00000578105.1
ENST00000330137.12
ENST00000437036.6
SKA2
spindle and kinetochore associated complex subunit 2
chr1_-_221742074 0.15 ENST00000366899.4
DUSP10
dual specificity phosphatase 10
chr1_+_155308930 0.15 ENST00000465559.5
ENST00000612683.1
FDPS
farnesyl diphosphate synthase
chr11_-_72112750 0.15 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
ANAPC15
anaphase promoting complex subunit 15
chr14_+_94174334 0.15 ENST00000328839.3
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr3_+_158801926 0.14 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
MFSD1
major facilitator superfamily domain containing 1
chr17_+_47209035 0.13 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
MYL4
myosin light chain 4
chr14_+_94174284 0.13 ENST00000304338.8
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr7_-_73842508 0.13 ENST00000297873.9
METTL27
methyltransferase like 27
chr8_+_93917045 0.13 ENST00000518573.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_100119291 0.13 ENST00000431404.2
TAF6
TATA-box binding protein associated factor 6
chr16_+_590056 0.13 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C
RAB40C, member RAS oncogene family
chr10_-_97445850 0.12 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
EXOSC1
exosome component 1
chr11_-_72112669 0.12 ENST00000545944.5
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr11_-_111871271 0.12 ENST00000398006.6
ALG9
ALG9 alpha-1,2-mannosyltransferase
chr12_+_102120240 0.12 ENST00000537257.5
ENST00000392911.6
PARPBP
PARP1 binding protein
chr3_-_105868964 0.11 ENST00000394030.8
CBLB
Cbl proto-oncogene B
chr10_+_1049476 0.11 ENST00000358220.5
WDR37
WD repeat domain 37
chr15_-_74906872 0.11 ENST00000562698.5
FAM219B
family with sequence similarity 219 member B
chr9_+_113463697 0.11 ENST00000317613.10
RGS3
regulator of G protein signaling 3
chr11_-_62754141 0.10 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
ZBTB3
zinc finger and BTB domain containing 3
chr3_-_105869035 0.10 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
CBLB
Cbl proto-oncogene B
chr12_+_64405046 0.10 ENST00000540203.5
XPOT
exportin for tRNA
chr11_-_4608226 0.10 ENST00000300747.10
ENST00000526337.5
TRIM68
tripartite motif containing 68
chr19_-_8005590 0.09 ENST00000407627.7
ENST00000593807.1
ELAVL1
ELAV like RNA binding protein 1
chr19_+_56141317 0.09 ENST00000592949.5
ZNF444
zinc finger protein 444
chr4_-_53365941 0.09 ENST00000611795.1
SCFD2
sec1 family domain containing 2
chr1_+_161721563 0.08 ENST00000367948.6
FCRLB
Fc receptor like B
chr11_+_73272332 0.08 ENST00000540124.6
ENST00000536225.2
P2RY6
pyrimidinergic receptor P2Y6
chr5_+_67004618 0.08 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr13_-_110242694 0.08 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
COL4A1
collagen type IV alpha 1 chain
chr11_-_106022209 0.08 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr4_+_3074661 0.08 ENST00000355072.11
HTT
huntingtin
chr15_+_64094060 0.07 ENST00000560829.5
SNX1
sorting nexin 1
chrX_-_23743201 0.07 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
ACOT9
acyl-CoA thioesterase 9
chr3_+_39387795 0.07 ENST00000642978.1
SLC25A38
solute carrier family 25 member 38
chr8_-_167024 0.06 ENST00000320901.4
OR4F21
olfactory receptor family 4 subfamily F member 21
chr1_-_197146688 0.06 ENST00000294732.11
ASPM
assembly factor for spindle microtubules
chr11_-_125111708 0.06 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr6_-_31862809 0.06 ENST00000375631.5
NEU1
neuraminidase 1
chr19_+_49766962 0.05 ENST00000354293.10
ENST00000359032.9
AP2A1
adaptor related protein complex 2 subunit alpha 1
chr20_-_41618362 0.05 ENST00000373222.3
ENST00000373233.8
CHD6
chromodomain helicase DNA binding protein 6
chrX_+_55000329 0.05 ENST00000374987.4
APEX2
apurinic/apyrimidinic endodeoxyribonuclease 2
chr9_+_72577369 0.05 ENST00000651183.1
TMC1
transmembrane channel like 1
chr17_-_42185452 0.04 ENST00000293330.1
HCRT
hypocretin neuropeptide precursor
chr1_+_174874434 0.04 ENST00000478442.5
ENST00000465412.5
RABGAP1L
RAB GTPase activating protein 1 like
chr19_-_45782388 0.04 ENST00000458663.6
DMPK
DM1 protein kinase
chrX_+_137566119 0.04 ENST00000287538.10
ZIC3
Zic family member 3
chr10_-_124418912 0.03 ENST00000368845.6
ENST00000539214.5
OAT
ornithine aminotransferase
chr22_-_38755458 0.03 ENST00000405510.5
ENST00000433561.5
SUN2
Sad1 and UNC84 domain containing 2
chr10_-_54801179 0.03 ENST00000373955.5
PCDH15
protocadherin related 15
chr19_-_45782479 0.03 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DMPK
DM1 protein kinase
chr6_-_73395133 0.02 ENST00000441145.1
OOEP
oocyte expressed protein
chr11_+_119334511 0.02 ENST00000311413.5
RNF26
ring finger protein 26
chr5_+_64505981 0.02 ENST00000334025.3
RGS7BP
regulator of G protein signaling 7 binding protein
chr10_-_1049110 0.02 ENST00000381344.8
IDI1
isopentenyl-diphosphate delta isomerase 1
chr7_+_100049765 0.01 ENST00000456748.6
ENST00000292450.9
ENST00000438937.1
ENST00000543588.2
ZSCAN21
zinc finger and SCAN domain containing 21
chr14_-_24242567 0.00 ENST00000558476.5
TINF2
TERF1 interacting nuclear factor 2
chr7_+_120988683 0.00 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.2 GO:0072244 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 2.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 0.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.0 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 0.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.4 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.8 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.9 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:1900920 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 9.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:1990032 parallel fiber(GO:1990032)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.7 GO:0043295 glutathione binding(GO:0043295)
0.3 1.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.6 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors