ISMARA results: NKX3-1

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avrg: Illumina Body Map 2 (GSE30611)

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Results for NKX3-1

Z-value: 1.27

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Transcription factors associated with NKX3-1

Gene Symbol	Gene ID	Gene Info
NKX3-1 Ensembl NCBI GeneCards UniProt	ENSG00000167034.10	NKX3-1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX3-1	hg38_v1_chr8_-_23682889_23682951	-0.24	1.9e-01	Click!

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr7_-_120858066 Show fit	3.10	ENST00000222747.8	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr16_-_69726506 Show fit	2.12	ENST00000561500.5 ENST00000320623.10 ENST00000439109.6 ENST00000564043.1 ENST00000379046.6 ENST00000379047.7	NQO1 Ensembl NCBI GeneCards UniProt Show fit	NAD(P)H quinone dehydrogenase 1
chr15_+_99105071 Show fit	1.88	ENST00000328642.11 ENST00000594047.2 ENST00000336292.11	SYNM Ensembl NCBI GeneCards UniProt Show fit	synemin
chr19_-_42427379 Show fit	1.87	ENST00000244289.9	LIPE Ensembl NCBI GeneCards UniProt Show fit	lipase E, hormone sensitive type
chr12_+_109131350 Show fit	1.85	ENST00000539864.1	ACACB Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA carboxylase beta
chr9_+_706841 Show fit	1.79	ENST00000382293.7	KANK1 Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 1
chr5_-_43412323 Show fit	1.72	ENST00000361115.4	CCL28 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 28
chr4_+_158210479 Show fit	1.67	ENST00000504569.5 ENST00000509278.5 ENST00000514558.5 ENST00000503200.5 ENST00000296529.11	TMEM144 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 144
chr11_-_19201976 Show fit	1.64	ENST00000647990.1 ENST00000649235.1 ENST00000265968.9 ENST00000649842.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr20_-_57710539 Show fit	1.59	ENST00000395816.7 ENST00000347215.8	PMEPA1 Ensembl NCBI GeneCards UniProt Show fit	prostate transmembrane protein, androgen induced 1
chr7_+_80135694 Show fit	1.53	ENST00000457358.7	GNAI1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i1
chr12_-_16600703 Show fit	1.49	ENST00000616247.4	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr6_-_123636997 Show fit	1.47	ENST00000546248.5	TRDN Ensembl NCBI GeneCards UniProt Show fit	triadin
chr4_-_137532452 Show fit	1.38	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr3_-_81761636 Show fit	1.33	ENST00000429644.7	GBE1 Ensembl NCBI GeneCards UniProt Show fit	1,4-alpha-glucan branching enzyme 1
chr6_-_127459364 Show fit	1.31	ENST00000487331.2 ENST00000483725.8	KIAA0408 Ensembl NCBI GeneCards UniProt Show fit	KIAA0408
chr6_-_123636979 Show fit	1.27	ENST00000662930.1	TRDN Ensembl NCBI GeneCards UniProt Show fit	triadin
chr10_+_86968432 Show fit	1.15	ENST00000416348.1 ENST00000372013.8	ADIRF Ensembl NCBI GeneCards UniProt Show fit	adipogenesis regulatory factor
chr3_-_69200711 Show fit	1.15	ENST00000478263.5 ENST00000462512.1	FRMD4B Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 4B
chr14_-_74084393 Show fit	1.13	ENST00000350259.8 ENST00000553458.6	ALDH6A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 6 family member A1
chr8_-_61651086 Show fit	1.13	ENST00000524173.5	ASPH Ensembl NCBI GeneCards UniProt Show fit	aspartate beta-hydroxylase
chr18_-_36798482 Show fit	1.10	ENST00000590258.2	TPGS2 Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr6_-_123636923 Show fit	1.09	ENST00000334268.9	TRDN Ensembl NCBI GeneCards UniProt Show fit	triadin
chr5_+_151025343 Show fit	1.08	ENST00000521632.1	GPX3 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 3
chr7_+_107660819 Show fit	1.07	ENST00000644269.2	SLC26A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 4
chr6_-_53510445 Show fit	1.04	ENST00000509541.5	GCLC Ensembl NCBI GeneCards UniProt Show fit	glutamate-cysteine ligase catalytic subunit
chr11_-_19202004 Show fit	1.03	ENST00000648719.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr2_-_178702479 Show fit	0.99	ENST00000414766.5	TTN Ensembl NCBI GeneCards UniProt Show fit	titin
chr17_+_50532713 Show fit	0.98	ENST00000503690.5 ENST00000514874.5 ENST00000268933.8	EPN3 Ensembl NCBI GeneCards UniProt Show fit	epsin 3
chr19_-_53132873 Show fit	0.98	ENST00000601493.5 ENST00000599261.5 ENST00000597503.5 ENST00000500065.8 ENST00000594011.5 ENST00000595193.5 ENST00000595813.5 ENST00000600574.5 ENST00000596051.1 ENST00000601110.5 ENST00000243643.9 ENST00000421033.5	ZNF415 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 415
chr12_+_119593758 Show fit	0.91	ENST00000426426.3	TMEM233 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 233
chr9_-_14180779 Show fit	0.91	ENST00000380924.1 ENST00000543693.5	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr15_-_43220989 Show fit	0.91	ENST00000540029.5 ENST00000441366.7 ENST00000648595.1	EPB42 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.2
chr4_+_158210444 Show fit	0.90	ENST00000512481.5	TMEM144 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 144
chr2_+_63842102 Show fit	0.89	ENST00000626380.2 ENST00000497883.5	UGP2 Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose pyrophosphorylase 2
chr7_-_120857124 Show fit	0.89	ENST00000441017.5 ENST00000424710.5 ENST00000433758.5	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chrX_+_115561162 Show fit	0.88	ENST00000355899.8 ENST00000626746.2 ENST00000289290.7	PLS3 Ensembl NCBI GeneCards UniProt Show fit	plastin 3
chr4_+_158210194 Show fit	0.87	ENST00000508243.5	TMEM144 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 144
chr15_-_33067884 Show fit	0.85	ENST00000334528.13	FMN1 Ensembl NCBI GeneCards UniProt Show fit	formin 1
chr8_-_61689768 Show fit	0.82	ENST00000517847.6 ENST00000389204.8 ENST00000517661.5 ENST00000517903.5 ENST00000522603.5 ENST00000541428.5 ENST00000522349.5 ENST00000522835.5 ENST00000518306.5	ASPH Ensembl NCBI GeneCards UniProt Show fit	aspartate beta-hydroxylase
chr9_+_127642343 Show fit	0.82	ENST00000626333.1	STXBP1 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 1
chr2_+_63841882 Show fit	0.81	ENST00000337130.10 ENST00000488245.6	UGP2 Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose pyrophosphorylase 2
chr15_-_33068143 Show fit	0.81	ENST00000558197.1	FMN1 Ensembl NCBI GeneCards UniProt Show fit	formin 1
chr5_-_177462379 Show fit	0.80	ENST00000512501.1	DBN1 Ensembl NCBI GeneCards UniProt Show fit	drebrin 1
chr8_+_30442602 Show fit	0.79	ENST00000520191.5	RBPMS Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein, mRNA processing factor
chr16_+_83953232 Show fit	0.79	ENST00000565123.5 ENST00000393306.6	OSGIN1 Ensembl NCBI GeneCards UniProt Show fit	oxidative stress induced growth inhibitor 1
chr6_-_123636966 Show fit	0.79	ENST00000542443.5	TRDN Ensembl NCBI GeneCards UniProt Show fit	triadin
chr9_-_113340248 Show fit	0.79	ENST00000341761.8 ENST00000374195.7 ENST00000374193.9	WDR31 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 31
chr5_+_126423176 Show fit	0.78	ENST00000542322.5 ENST00000544396.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr3_+_159273235 Show fit	0.77	ENST00000638749.1	IQCJ-SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	IQCJ-SCHIP1 readthrough
chr1_+_202462730 Show fit	0.77	ENST00000290419.9 ENST00000491336.5	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr7_+_80624071 Show fit	0.77	ENST00000438020.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr1_-_31704001 Show fit	0.76	ENST00000373672.8	COL16A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XVI alpha 1 chain
chr1_-_225567270 Show fit	0.76	ENST00000497899.6	ENAH Ensembl NCBI GeneCards UniProt Show fit	ENAH actin regulator
chr7_+_107661002 Show fit	0.76	ENST00000440056.1	SLC26A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 4
chr7_+_16661182 Show fit	0.76	ENST00000446596.5 ENST00000452975.6 ENST00000438834.5	BZW2 Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper and W2 domains 2
chr10_-_60141004 Show fit	0.76	ENST00000355288.6	ANK3 Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr1_-_216805367 Show fit	0.75	ENST00000360012.7	ESRRG Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor gamma
chr14_-_88551460 Show fit	0.74	ENST00000555243.1	PTPN21 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 21
chr2_+_63842325 Show fit	0.73	ENST00000445915.6 ENST00000475462.5	UGP2 Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose pyrophosphorylase 2
chr1_-_160262501 Show fit	0.73	ENST00000447377.5	DCAF8 Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 8
chr9_+_72114595 Show fit	0.72	ENST00000545168.5	GDA Ensembl NCBI GeneCards UniProt Show fit	guanine deaminase
chr2_-_150487658 Show fit	0.71	ENST00000375734.6 ENST00000263895.9 ENST00000454202.5	RND3 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 3
chr1_+_171248471 Show fit	0.69	ENST00000402921.6 ENST00000617670.6 ENST00000367750.7	FMO1 Ensembl NCBI GeneCards UniProt Show fit	flavin containing dimethylaniline monoxygenase 1
chr4_-_46124046 Show fit	0.68	ENST00000295452.5	GABRG1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma1
chr5_+_79111802 Show fit	0.66	ENST00000524080.1 ENST00000274353.10	BHMT Ensembl NCBI GeneCards UniProt Show fit	betaine--homocysteine S-methyltransferase
chr12_-_21910853 Show fit	0.65	ENST00000544039.5	ABCC9 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily C member 9
chr14_+_74084947 Show fit	0.65	ENST00000674221.1 ENST00000554938.2	LIN52 Ensembl NCBI GeneCards UniProt Show fit	lin-52 DREAM MuvB core complex component
chr18_+_58362467 Show fit	0.64	ENST00000675101.1	NEDD4L Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr10_+_18340699 Show fit	0.63	ENST00000377329.10	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chr10_-_32056376 Show fit	0.63	ENST00000302418.5	KIF5B Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 5B
chr21_-_25734887 Show fit	0.63	ENST00000400094.5 ENST00000284971.8	ATP5PF Ensembl NCBI GeneCards UniProt Show fit	ATP synthase peripheral stalk subunit F6
chr10_-_96357155 Show fit	0.62	ENST00000536387.5	OPALIN Ensembl NCBI GeneCards UniProt Show fit	oligodendrocytic myelin paranodal and inner loop protein
chr13_+_24309565 Show fit	0.62	ENST00000332018.4	C1QTNF9 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 9
chr4_-_74794514 Show fit	0.62	ENST00000395743.8	BTC Ensembl NCBI GeneCards UniProt Show fit	betacellulin
chr11_+_8019193 Show fit	0.62	ENST00000534099.5	TUB Ensembl NCBI GeneCards UniProt Show fit	TUB bipartite transcription factor
chr5_+_179698367 Show fit	0.62	ENST00000680406.1 ENST00000502296.6 ENST00000504734.5	CANX Ensembl NCBI GeneCards UniProt Show fit	calnexin
chr5_+_126423122 Show fit	0.62	ENST00000515200.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr8_-_96235533 Show fit	0.61	ENST00000518406.5 ENST00000287022.10 ENST00000523920.1	UQCRB Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase binding protein
chr11_+_102112445 Show fit	0.61	ENST00000524575.5	YAP1 Ensembl NCBI GeneCards UniProt Show fit	Yes1 associated transcriptional regulator
chrX_-_31266925 Show fit	0.61	ENST00000680557.1 ENST00000378680.6 ENST00000378723.7 ENST00000680768.2 ENST00000681870.1 ENST00000680355.1 ENST00000682322.1 ENST00000682600.1 ENST00000680162.2 ENST00000681153.1 ENST00000681334.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr6_+_150683593 Show fit	0.61	ENST00000644968.1	PLEKHG1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and RhoGEF domain containing G1
chr16_+_22513058 Show fit	0.60	ENST00000536620.1	NPIPB5 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member B5
chr3_+_98763331 Show fit	0.60	ENST00000485391.5 ENST00000492254.5	ST3GAL6 Ensembl NCBI GeneCards UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr12_+_110614097 Show fit	0.60	ENST00000471804.7 ENST00000377654.5 ENST00000614115.5 ENST00000397655.7 ENST00000549123.6 ENST00000679401.1 ENST00000397659.9 ENST00000680445.1	TCTN1 Ensembl NCBI GeneCards UniProt Show fit	tectonic family member 1
chr17_+_70104991 Show fit	0.59	ENST00000587698.5 ENST00000587892.1	KCNJ16 Ensembl NCBI GeneCards UniProt Show fit	potassium inwardly rectifying channel subfamily J member 16
chr19_+_12969568 Show fit	0.59	ENST00000317060.4	DAND5 Ensembl NCBI GeneCards UniProt Show fit	DAN domain BMP antagonist family member 5
chr19_+_54105923 Show fit	0.58	ENST00000420296.1	NDUFA3 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A3
chr1_+_173824626 Show fit	0.56	ENST00000648960.1 ENST00000648807.1 ENST00000649067.1 ENST00000649689.2	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr10_-_27240505 Show fit	0.56	ENST00000375888.5 ENST00000676732.1	ACBD5 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA binding domain containing 5
chr12_-_262828 Show fit	0.55	ENST00000343164.9 ENST00000436453.1 ENST00000445055.6 ENST00000546319.5	SLC6A13 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 13
chr11_+_57805541 Show fit	0.55	ENST00000683201.1 ENST00000683769.1	CTNND1 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 1
chr7_+_80199266 Show fit	0.54	ENST00000647672.1	GNAI1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i1
chr9_-_83063159 Show fit	0.53	ENST00000340717.4	RASEF Ensembl NCBI GeneCards UniProt Show fit	RAS and EF-hand domain containing
chr11_+_111918014 Show fit	0.52	ENST00000529342.5	C11orf52 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 52
chr3_-_160399207 Show fit	0.51	ENST00000465537.5 ENST00000486856.5 ENST00000468218.5 ENST00000478370.5 ENST00000326448.12	IFT80 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 80
chr3_-_48595267 Show fit	0.50	ENST00000328333.12 ENST00000681320.1	COL7A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type VII alpha 1 chain
chr17_+_50532681 Show fit	0.50	ENST00000503246.1	EPN3 Ensembl NCBI GeneCards UniProt Show fit	epsin 3
chr9_+_107306459 Show fit	0.49	ENST00000457811.1	RAD23B Ensembl NCBI GeneCards UniProt Show fit	RAD23 homolog B, nucleotide excision repair protein
chr1_+_173824694 Show fit	0.49	ENST00000647645.1	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr16_-_66830903 Show fit	0.49	ENST00000566336.5 ENST00000394074.6 ENST00000563185.6 ENST00000359087.8 ENST00000290810.8 ENST00000379463.6 ENST00000565535.5	NAE1 Ensembl NCBI GeneCards UniProt Show fit	NEDD8 activating enzyme E1 subunit 1
chr13_+_23570370 Show fit	0.48	ENST00000403372.6 ENST00000248484.9	TNFRSF19 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 19
chr3_+_138608575 Show fit	0.48	ENST00000338446.8	FAIM Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr10_+_16436996 Show fit	0.48	ENST00000535784.7	PTER Ensembl NCBI GeneCards UniProt Show fit	phosphotriesterase related
chr13_+_114235044 Show fit	0.48	ENST00000252457.9 ENST00000375308.5	CDC16 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 16
chr2_-_27323072 Show fit	0.48	ENST00000428910.5 ENST00000402722.5 ENST00000380044.6 ENST00000399052.8 ENST00000405076.5	MPV17 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr5_-_138875362 Show fit	0.48	ENST00000518785.1	LRRTM2 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 2
chr2_-_101387453 Show fit	0.47	ENST00000324768.6	CREG2 Ensembl NCBI GeneCards UniProt Show fit	cellular repressor of E1A stimulated genes 2
chr7_+_142666272 Show fit	0.47	ENST00000604952.1	MTRNR2L6 Ensembl NCBI GeneCards UniProt Show fit	MT-RNR2 like 6
chr10_-_73252601 Show fit	0.47	ENST00000372945.8 ENST00000372940.3	MRPS16 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S16
chr17_+_17179527 Show fit	0.47	ENST00000579361.1	MPRIP Ensembl NCBI GeneCards UniProt Show fit	myosin phosphatase Rho interacting protein
chr11_-_62556230 Show fit	0.46	ENST00000530285.5	AHNAK Ensembl NCBI GeneCards UniProt Show fit	AHNAK nucleoprotein
chr2_-_55269207 Show fit	0.46	ENST00000263629.9 ENST00000403721.5	MTIF2 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial translational initiation factor 2
chr3_-_160399512 Show fit	0.45	ENST00000498409.5 ENST00000475677.5 ENST00000478536.1	IFT80 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 80
chr4_+_86936386 Show fit	0.45	ENST00000511442.1	AFF1 Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family member 1
chr10_+_3104676 Show fit	0.45	ENST00000415005.6 ENST00000468050.1	PFKP Ensembl NCBI GeneCards UniProt Show fit	phosphofructokinase, platelet
chr6_-_134950081 Show fit	0.45	ENST00000367847.2 ENST00000265605.7 ENST00000367845.6	ALDH8A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 8 family member A1
chr1_-_157099798 Show fit	0.44	ENST00000454449.3	ETV3L Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 3 like
chr1_+_156369202 Show fit	0.44	ENST00000537040.6	RHBG Ensembl NCBI GeneCards UniProt Show fit	Rh family B glycoprotein
chr10_+_101588274 Show fit	0.44	ENST00000626968.2 ENST00000370151.9 ENST00000370147.5	DPCD Ensembl NCBI GeneCards UniProt Show fit	deleted in primary ciliary dyskinesia homolog (mouse)
chrX_+_10156960 Show fit	0.44	ENST00000380833.9	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr19_+_51571249 Show fit	0.44	ENST00000262259.7 ENST00000545217.5 ENST00000596504.1	ZNF175 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 175
chr1_-_160262407 Show fit	0.43	ENST00000419626.1 ENST00000610139.5 ENST00000475733.5 ENST00000407642.6 ENST00000368073.7 ENST00000326837.6	DCAF8 Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 8
chr21_+_34364003 Show fit	0.43	ENST00000290310.4	KCNE2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily E regulatory subunit 2
chr13_+_114235066 Show fit	0.42	ENST00000252458.6	CDC16 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 16
chr12_+_10213624 Show fit	0.42	ENST00000545290.1	GABARAPL1 Ensembl NCBI GeneCards UniProt Show fit	GABA type A receptor associated protein like 1
chr12_+_110614027 Show fit	0.41	ENST00000550703.6 ENST00000551590.5	TCTN1 Ensembl NCBI GeneCards UniProt Show fit	tectonic family member 1
chr4_+_143433491 Show fit	0.41	ENST00000512843.1	GAB1 Ensembl NCBI GeneCards UniProt Show fit	GRB2 associated binding protein 1
chr11_+_59436469 Show fit	0.40	ENST00000641045.1	OR5A1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily A member 1
chr5_+_141392616 Show fit	0.40	ENST00000398604.3	PCDHGA8 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 8
chr1_+_95151377 Show fit	0.40	ENST00000604203.1	TLCD4-RWDD3 Ensembl NCBI GeneCards UniProt Show fit	TLCD4-RWDD3 readthrough
chr1_-_31704319 Show fit	0.40	ENST00000373668.7	COL16A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XVI alpha 1 chain
chr22_+_44031345 Show fit	0.39	ENST00000444029.5	PARVB Ensembl NCBI GeneCards UniProt Show fit	parvin beta
chr6_+_28267355 Show fit	0.39	ENST00000614088.1 ENST00000619937.4	ZSCAN26 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and SCAN domain containing 26
chr3_+_98763315 Show fit	0.39	ENST00000468553.5	ST3GAL6 Ensembl NCBI GeneCards UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr6_-_57222244 Show fit	0.38	ENST00000468148.6	RAB23 Ensembl NCBI GeneCards UniProt Show fit	RAB23, member RAS oncogene family
chr10_+_18340821 Show fit	0.38	ENST00000612743.1 ENST00000612134.4	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chr9_-_83063135 Show fit	0.38	ENST00000376447.4	RASEF Ensembl NCBI GeneCards UniProt Show fit	RAS and EF-hand domain containing
chr19_-_5719849 Show fit	0.38	ENST00000590729.5	LONP1 Ensembl NCBI GeneCards UniProt Show fit	lon peptidase 1, mitochondrial
chr12_-_56645955 Show fit	0.37	ENST00000552959.5 ENST00000551020.5 ENST00000553007.2 ENST00000262030.8	ATP5F1B Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr1_-_160262540 Show fit	0.37	ENST00000368074.6	DCAF8 Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 8
chr5_+_150497772 Show fit	0.37	ENST00000523767.5	NDST1 Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase and N-sulfotransferase 1
chr13_+_94601830 Show fit	0.37	ENST00000376958.5	GPR180 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 180
chr15_-_43584864 Show fit	0.37	ENST00000381885.5 ENST00000396923.7	PPIP5K1 Ensembl NCBI GeneCards UniProt Show fit	diphosphoinositol pentakisphosphate kinase 1
chrX_+_86148441 Show fit	0.37	ENST00000373125.9 ENST00000373131.5	DACH2 Ensembl NCBI GeneCards UniProt Show fit	dachshund family transcription factor 2
chr14_+_60982477 Show fit	0.37	ENST00000533744.6	SLC38A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 6
chr18_+_63476927 Show fit	0.36	ENST00000489441.5 ENST00000382771.9 ENST00000424602.1	SERPINB5 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 5
chr10_-_89643870 Show fit	0.36	ENST00000322191.10 ENST00000342512.3	PANK1 Ensembl NCBI GeneCards UniProt Show fit	pantothenate kinase 1
chr11_-_61920267 Show fit	0.36	ENST00000531922.2 ENST00000301773.9	RAB3IL1 Ensembl NCBI GeneCards UniProt Show fit	RAB3A interacting protein like 1
chr16_+_57372465 Show fit	0.36	ENST00000563383.1	CX3CL1 Ensembl NCBI GeneCards UniProt Show fit	C-X3-C motif chemokine ligand 1
chr1_-_149813687 Show fit	0.35	ENST00000331491.2	H3C13 Ensembl NCBI GeneCards UniProt Show fit	H3 clustered histone 13
chr2_-_55269038 Show fit	0.35	ENST00000417363.5 ENST00000412530.1 ENST00000366137.6 ENST00000420637.5	MTIF2 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial translational initiation factor 2
chr19_-_12597298 Show fit	0.35	ENST00000440366.1	ZNF490 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 490
chr11_+_64305497 Show fit	0.35	ENST00000406310.6 ENST00000677967.1 ENST00000000442.11	ESRRA Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor alpha
chr3_+_169966764 Show fit	0.34	ENST00000337002.9 ENST00000480708.5	SEC62 Ensembl NCBI GeneCards UniProt Show fit	SEC62 homolog, preprotein translocation factor
chr1_-_160262522 Show fit	0.34	ENST00000440682.5	DCAF8 Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 8
chr16_+_3018390 Show fit	0.33	ENST00000573001.5	TNFRSF12A Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 12A
chr16_+_57372481 Show fit	0.33	ENST00000006053.7	CX3CL1 Ensembl NCBI GeneCards UniProt Show fit	C-X3-C motif chemokine ligand 1
chr4_-_46388713 Show fit	0.33	ENST00000507069.5	GABRA2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha2
chr6_+_53065385 Show fit	0.33	ENST00000323557.12	FBXO9 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 9
chr2_-_27323006 Show fit	0.32	ENST00000402310.5 ENST00000405983.5 ENST00000403262.6	MPV17 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial inner membrane protein MPV17
chr3_-_179259208 Show fit	0.32	ENST00000485523.5	KCNMB3 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr14_-_53953415 Show fit	0.32	ENST00000559501.1 ENST00000558984.1	BMP4 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 4
chr1_-_74733253 Show fit	0.32	ENST00000417775.5	CRYZ Ensembl NCBI GeneCards UniProt Show fit	crystallin zeta
chr1_+_173824956 Show fit	0.32	ENST00000648458.1	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr19_-_2944909 Show fit	0.31	ENST00000314531.5	ZNF77 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 77
chr2_+_101839815 Show fit	0.31	ENST00000421882.5	MAP4K4 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_75556048 Show fit	0.30	ENST00000616557.1 ENST00000435974.2 ENST00000311623.9	ODAPH Ensembl NCBI GeneCards UniProt Show fit	odontogenesis associated phosphoprotein
chr11_-_72112750 Show fit	0.30	ENST00000545680.5 ENST00000543587.5 ENST00000538393.5 ENST00000535234.5 ENST00000227618.8 ENST00000535503.5	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr14_+_94612383 Show fit	0.30	ENST00000393080.8 ENST00000555820.1 ENST00000393078.5 ENST00000467132.5	SERPINA3 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 3
chr8_+_38176802 Show fit	0.30	ENST00000287322.5	BAG4 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 4
chr3_+_100709290 Show fit	0.30	ENST00000675047.1 ENST00000490574.6 ENST00000675543.1 ENST00000676308.1 ENST00000675499.1	TFG Ensembl NCBI GeneCards UniProt Show fit	trafficking from ER to golgi regulator
chr17_+_82716698 Show fit	0.30	ENST00000269373.11 ENST00000577128.1 ENST00000573158.5	FN3KRP Ensembl NCBI GeneCards UniProt Show fit	fructosamine 3 kinase related protein
chr3_+_155083889 Show fit	0.29	ENST00000680282.1	MME Ensembl NCBI GeneCards UniProt Show fit	membrane metalloendopeptidase
chr5_-_41510623 Show fit	0.29	ENST00000328457.5	PLCXD3 Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol specific phospholipase C X domain containing 3
chr11_-_72112669 Show fit	0.29	ENST00000545944.5 ENST00000502597.2	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr11_-_117817500 Show fit	0.29	ENST00000525836.1	DSCAML1 Ensembl NCBI GeneCards UniProt Show fit	DS cell adhesion molecule like 1
chr6_-_79537423 Show fit	0.29	ENST00000369846.9 ENST00000392959.5 ENST00000467898.3	LCA5 Ensembl NCBI GeneCards UniProt Show fit	lebercilin LCA5
chr2_-_201739205 Show fit	0.28	ENST00000681558.1 ENST00000681495.1	ALS2 Ensembl NCBI GeneCards UniProt Show fit	alsin Rho guanine nucleotide exchange factor ALS2
chr6_+_24775413 Show fit	0.28	ENST00000378054.6 ENST00000620958.4 ENST00000476555.5	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr3_-_48695492 Show fit	0.27	ENST00000453202.1	IP6K2 Ensembl NCBI GeneCards UniProt Show fit	inositol hexakisphosphate kinase 2
chr4_-_170003738 Show fit	0.27	ENST00000502832.1 ENST00000393704.3	MFAP3L Ensembl NCBI GeneCards UniProt Show fit	microfibril associated protein 3 like
chr14_-_67600258 Show fit	0.27	ENST00000559581.5 ENST00000216452.9 ENST00000560722.5 ENST00000559415.1	PIGH Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class H
chr11_-_118565992 Show fit	0.27	ENST00000264020.6	IFT46 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 46
chr13_+_111241185 Show fit	0.27	ENST00000478679.5	ARHGEF7 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 7
chr20_+_19886506 Show fit	0.27	ENST00000648440.1	RIN2 Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 2
chr13_-_44474296 Show fit	0.27	ENST00000611198.4	TSC22D1 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 1
chrX_-_31266857 Show fit	0.26	ENST00000378702.8 ENST00000361471.8	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr15_-_28322179 Show fit	0.25	ENST00000261609.13	HERC2 Ensembl NCBI GeneCards UniProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr12_+_80716906 Show fit	0.24	ENST00000228644.4	MYF5 Ensembl NCBI GeneCards UniProt Show fit	myogenic factor 5
chr2_+_201129826 Show fit	0.24	ENST00000457277.5	CFLAR Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr5_+_150671588 Show fit	0.24	ENST00000523553.1	MYOZ3 Ensembl NCBI GeneCards UniProt Show fit	myozenin 3
chr6_+_28267107 Show fit	0.24	ENST00000621053.1 ENST00000617168.4 ENST00000421553.7 ENST00000611552.2 ENST00000623276.3	ENSG00000276302.1 Ensembl NCBI GeneCards UniProt Show fit ZSCAN26 Ensembl NCBI GeneCards UniProt Show fit	novel protein zinc finger and SCAN domain containing 26
chr17_+_35587239 Show fit	0.24	ENST00000621914.4 ENST00000621668.4 ENST00000616681.4 ENST00000612035.4 ENST00000610402.5 ENST00000614600.4 ENST00000590432.5 ENST00000612116.5	AP2B1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 2 subunit beta 1
chr11_+_64305550 Show fit	0.24	ENST00000539594.5	ESRRA Ensembl NCBI GeneCards UniProt Show fit	estrogen related receptor alpha
chr1_-_152806628 Show fit	0.23	ENST00000606576.1 ENST00000607093.2	LCE1C Ensembl NCBI GeneCards UniProt Show fit	late cornified envelope 1C
chr17_-_41505597 Show fit	0.23	ENST00000336861.7 ENST00000246635.8 ENST00000587544.5 ENST00000587435.1	KRT13 Ensembl NCBI GeneCards UniProt Show fit	keratin 13
chr11_-_101583503 Show fit	0.23	ENST00000348423.8 ENST00000360497.4 ENST00000532133.5	TRPC6 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 6
chr15_-_43584504 Show fit	0.23	ENST00000348806.10	PPIP5K1 Ensembl NCBI GeneCards UniProt Show fit	diphosphoinositol pentakisphosphate kinase 1
chr3_+_139343996 Show fit	0.23	ENST00000680020.1 ENST00000310776.9 ENST00000465373.5	MRPS22 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S22

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	4.6	GO:1901846	positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.5	1.9	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.5	1.4	GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145)
0.4	1.8	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4	0.4	GO:1902159	regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.4	3.7	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	1.9	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.3	2.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.3	0.9	GO:0051041	positive regulation of calcium-independent cell-cell adhesion(GO:0051041)
0.3	1.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.3	1.9	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3	1.9	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.2	0.7	GO:0006147	guanine catabolic process(GO:0006147)
0.2	0.7	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
0.2	1.7	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2	1.0	GO:1904387	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.2	1.7	GO:0072092	ureteric bud invasion(GO:0072092)
0.2	0.8	GO:0070124	mitochondrial translational initiation(GO:0070124)
0.2	1.0	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.2	0.6	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.2	1.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.4	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	1.8	GO:0015705	iodide transport(GO:0015705)
0.1	1.5	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.8	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	1.2	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.4	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.1	2.1	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.6	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.1	0.9	GO:1900827	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.8	GO:1903294	regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1	1.0	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.3	GO:0090365	regulation of mRNA modification(GO:0090365)
0.1	0.9	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	4.0	GO:0010842	retina layer formation(GO:0010842)
0.1	1.8	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.2	GO:0044417	translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1	0.9	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.7	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.3	GO:0055018	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1	0.6	GO:0030242	pexophagy(GO:0030242)
0.1	0.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.8	GO:2000334	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1	0.5	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.3	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.1	0.6	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1	0.9	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.6	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	3.4	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.4	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.3	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.0	0.4	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.2	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.0	0.3	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.0	0.1	GO:1902896	intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0	0.1	GO:0051807	evasion or tolerance of host immune response(GO:0020012) evasion or tolerance of host defense response(GO:0030682) evasion or tolerance by virus of host immune response(GO:0030683) evasion or tolerance of immune response of other organism involved in symbiotic interaction(GO:0051805) evasion or tolerance of defense response of other organism involved in symbiotic interaction(GO:0051807)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.9	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.3	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.0	0.6	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.5	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	1.9	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	1.2	GO:0033622	integrin activation(GO:0033622)
0.0	0.8	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0	0.4	GO:0021678	third ventricle development(GO:0021678)
0.0	0.4	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.9	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.5	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.4	GO:0006477	protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.6	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.6	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.5	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.3	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	1.1	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.0	0.4	GO:2000394	regulation of GTP binding(GO:1904424) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	1.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.5	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	1.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.2	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.4	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.6	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	1.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.3	GO:0006828	manganese ion transport(GO:0006828)
0.0	1.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.0	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0	0.0	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.0	1.2	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.3	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.4	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.0	0.8	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	GO:0030934	anchoring collagen complex(GO:0030934)
0.4	1.9	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.3	4.6	GO:0033018	junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
0.2	1.0	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.1	1.9	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.6	GO:0071149	TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1	0.6	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.3	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	0.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	1.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.5	GO:0071942	XPC complex(GO:0071942)
0.1	0.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.9	GO:0016013	syntrophin complex(GO:0016013)
0.0	1.0	GO:0036038	MKS complex(GO:0036038)
0.0	1.0	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	1.4	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.6	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	1.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	1.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.6	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.8	GO:0005915	zonula adherens(GO:0005915)
0.0	0.6	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:1990498	mitotic spindle microtubule(GO:1990498)
0.0	0.4	GO:0000322	storage vacuole(GO:0000322)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	2.7	GO:0031526	brush border membrane(GO:0031526)
0.0	2.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	1.0	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.5	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.8	GO:0005921	gap junction(GO:0005921)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.3	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	4.1	GO:0030018	Z disc(GO:0030018)
0.0	1.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	1.9	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0003955	NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.6	1.9	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.5	1.5	GO:1990175	EH domain binding(GO:1990175)
0.5	1.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560)
0.4	2.4	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.3	1.9	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.3	1.8	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.3	0.9	GO:0031737	CX3C chemokine receptor binding(GO:0031737)
0.3	1.9	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.2	0.7	GO:0008892	guanine deaminase activity(GO:0008892)
0.2	3.9	GO:0031433	telethonin binding(GO:0031433)
0.2	1.0	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.2	1.0	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2	0.5	GO:0019781	NEDD8 activating enzyme activity(GO:0019781)
0.2	0.6	GO:0099609	microtubule lateral binding(GO:0099609)
0.1	4.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.8	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.4	GO:0070364	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1	2.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.7	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.1	0.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	1.9	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.7	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	0.9	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.8	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.6	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	1.0	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1	0.8	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	0.6	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	1.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	0.5	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.3	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1	0.4	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.4	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.5	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.0	0.6	GO:0016015	morphogen activity(GO:0016015)
0.0	0.9	GO:0008430	selenium binding(GO:0008430)
0.0	0.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	3.4	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	0.3	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.8	GO:0005522	profilin binding(GO:0005522)
0.0	1.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	2.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.4	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.6	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.4	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.9	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	1.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.4	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.3	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.0	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.5	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	5.5	GO:0044325	ion channel binding(GO:0044325)
0.0	0.6	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0030942	signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.8	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	1.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.5	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	2.1	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	2.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	2.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID EPO PATHWAY	EPO signaling pathway
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	1.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	2.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	1.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	1.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	2.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	2.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	1.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.8	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	2.0	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1

Results for NKX3-1

Z-value: 1.27

Motif logo

Transcription factors associated with NKX3-1

Activity-expression correlation:

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: