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avrg: Illumina Body Map 2 (GSE30611)

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Results for NR1D1

Z-value: 1.23

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Transcription factors associated with NR1D1

Gene Symbol Gene ID Gene Info
NR1D1
ENSG00000126368.6 NR1D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1D1hg38_v1_chr17_-_40100569_40100597-0.173.4e-01Click!

Activity profile of NR1D1 motif

Sorted Z-values of NR1D1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1D1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_24070837 3.08 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
CPNE6
copine 6
chr14_+_24071522 2.74 ENST00000558859.5
ENST00000559197.5
ENST00000560828.5
ENST00000560884.5
CPNE6
copine 6
chr14_+_24071552 2.64 ENST00000559207.1
CPNE6
copine 6
chr1_-_25906931 2.55 ENST00000357865.6
STMN1
stathmin 1
chr8_+_11704151 2.36 ENST00000526716.5
ENST00000532059.6
ENST00000335135.8
ENST00000622443.3
GATA4
GATA binding protein 4
chr8_-_109648825 2.31 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
SYBU
syntabulin
chr1_-_25906411 2.29 ENST00000455785.7
STMN1
stathmin 1
chr1_-_25905989 2.23 ENST00000399728.5
STMN1
stathmin 1
chr14_+_50533026 2.17 ENST00000441560.6
ATL1
atlastin GTPase 1
chr1_-_25906457 2.16 ENST00000426559.6
STMN1
stathmin 1
chr14_+_24070945 2.07 ENST00000559778.5
ENST00000560761.5
ENST00000557889.1
CPNE6
copine 6
chr4_-_21697755 1.99 ENST00000382148.7
KCNIP4
potassium voltage-gated channel interacting protein 4
chr8_+_104223320 1.84 ENST00000339750.3
RIMS2
regulating synaptic membrane exocytosis 2
chr5_-_43313473 1.83 ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr11_-_125496122 1.74 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
FEZ1
fasciculation and elongation protein zeta 1
chr5_-_43313403 1.65 ENST00000325110.11
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chrX_+_54920796 1.60 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
TRO
trophinin
chr11_+_60924452 1.54 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr19_-_18884219 1.46 ENST00000596048.1
CERS1
ceramide synthase 1
chr3_+_58237773 1.37 ENST00000478253.6
ABHD6
abhydrolase domain containing 6, acylglycerol lipase
chr7_-_29969927 1.37 ENST00000438497.5
SCRN1
secernin 1
chr6_-_169250825 1.36 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chr16_+_71358713 1.34 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
CALB2
calbindin 2
chr11_-_125495539 1.31 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1
chrX_+_16946862 1.27 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr1_+_109712227 1.25 ENST00000256593.8
GSTM5
glutathione S-transferase mu 5
chr6_+_75749231 1.19 ENST00000664209.1
ENST00000369975.6
ENST00000627432.3
ENST00000369985.9
ENST00000369977.8
ENST00000664640.1
ENST00000662603.1
MYO6
myosin VI
chr3_+_217535 1.17 ENST00000449294.6
CHL1
cell adhesion molecule L1 like
chr9_+_101028721 1.16 ENST00000374874.8
PLPPR1
phospholipid phosphatase related 1
chr2_+_63589135 1.15 ENST00000432309.6
MDH1
malate dehydrogenase 1
chr2_+_63588953 1.12 ENST00000409908.5
ENST00000442225.5
ENST00000233114.13
ENST00000539945.7
ENST00000409476.5
ENST00000436321.5
MDH1
malate dehydrogenase 1
chr8_-_109648746 1.02 ENST00000528045.5
SYBU
syntabulin
chr5_-_111976925 1.01 ENST00000395634.7
NREP
neuronal regeneration related protein
chr2_+_63588992 0.99 ENST00000454035.5
MDH1
malate dehydrogenase 1
chr14_+_100323332 0.98 ENST00000361529.5
ENST00000557052.1
SLC25A47
solute carrier family 25 member 47
chr1_+_109712272 0.95 ENST00000369812.6
GSTM5
glutathione S-transferase mu 5
chr8_-_144475808 0.91 ENST00000377317.5
FOXH1
forkhead box H1
chr11_+_46719193 0.86 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
F2
coagulation factor II, thrombin
chr6_+_75749192 0.82 ENST00000369981.7
MYO6
myosin VI
chr17_-_58280928 0.81 ENST00000225275.4
MPO
myeloperoxidase
chr13_+_100089015 0.81 ENST00000376286.8
ENST00000376279.7
ENST00000376285.6
PCCA
propionyl-CoA carboxylase subunit alpha
chr18_-_46757012 0.79 ENST00000315087.12
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr5_-_63962438 0.79 ENST00000323865.5
ENST00000506598.1
HTR1A
5-hydroxytryptamine receptor 1A
chr13_+_112969179 0.78 ENST00000535094.7
MCF2L
MCF.2 cell line derived transforming sequence like
chr17_-_2025289 0.78 ENST00000331238.7
RTN4RL1
reticulon 4 receptor like 1
chr8_+_104223344 0.73 ENST00000523362.5
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_159826860 0.73 ENST00000289707.10
SLAMF8
SLAM family member 8
chr13_+_112968496 0.71 ENST00000397030.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr1_-_11805977 0.70 ENST00000376486.3
MTHFR
methylenetetrahydrofolate reductase
chr5_+_141150012 0.70 ENST00000231136.4
ENST00000622991.1
PCDHB6
protocadherin beta 6
chr1_-_150971935 0.67 ENST00000368949.8
CERS2
ceramide synthase 2
chr6_+_75749272 0.66 ENST00000653423.1
MYO6
myosin VI
chr7_+_94509793 0.64 ENST00000297273.9
CASD1
CAS1 domain containing 1
chr17_-_39918589 0.63 ENST00000309481.11
GSDMB
gasdermin B
chr8_+_100150621 0.63 ENST00000522439.1
ENST00000353107.8
POLR2K
RNA polymerase II, I and III subunit K
chr1_-_11805924 0.62 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase
chr17_-_39918606 0.61 ENST00000418519.6
ENST00000520542.5
GSDMB
gasdermin B
chr1_+_159826799 0.59 ENST00000368104.4
SLAMF8
SLAM family member 8
chr2_-_102736819 0.58 ENST00000258436.10
MFSD9
major facilitator superfamily domain containing 9
chr1_+_218346235 0.57 ENST00000366929.4
TGFB2
transforming growth factor beta 2
chr10_+_22928030 0.57 ENST00000409983.7
ENST00000298032.10
ENST00000409049.7
ARMC3
armadillo repeat containing 3
chr19_+_21082190 0.57 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
ZNF714
zinc finger protein 714
chr19_-_42423100 0.57 ENST00000597001.1
LIPE
lipase E, hormone sensitive type
chr14_-_94129577 0.56 ENST00000238609.4
IFI27L2
interferon alpha inducible protein 27 like 2
chr19_+_35319261 0.56 ENST00000598537.5
CD22
CD22 molecule
chr1_+_2467437 0.55 ENST00000449969.5
PLCH2
phospholipase C eta 2
chr9_+_136327526 0.53 ENST00000440944.6
GPSM1
G protein signaling modulator 1
chr1_+_206205909 0.53 ENST00000624873.3
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr16_+_77191173 0.52 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1B
MON1 homolog B, secretory trafficking associated
chr10_+_133453936 0.49 ENST00000640237.1
SCART1
scavenger receptor family member expressed on T cells 1
chr17_-_78132407 0.48 ENST00000322914.7
TMC6
transmembrane channel like 6
chr1_-_11805949 0.47 ENST00000376590.9
MTHFR
methylenetetrahydrofolate reductase
chr17_+_50560703 0.47 ENST00000359106.10
CACNA1G
calcium voltage-gated channel subunit alpha1 G
chr11_+_111976902 0.47 ENST00000614104.4
DIXDC1
DIX domain containing 1
chr19_-_22422335 0.46 ENST00000357774.9
ENST00000601553.1
ENST00000593657.5
ZNF98
zinc finger protein 98
chr3_-_48685835 0.43 ENST00000439518.5
ENST00000416649.6
ENST00000294129.7
NCKIPSD
NCK interacting protein with SH3 domain
chr1_-_6497096 0.43 ENST00000537245.6
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
chr19_+_21082224 0.42 ENST00000620627.1
ZNF714
zinc finger protein 714
chr19_+_21082140 0.41 ENST00000616183.1
ENST00000596053.5
ZNF714
zinc finger protein 714
chr1_+_197413827 0.41 ENST00000367397.1
ENST00000681519.1
CRB1
crumbs cell polarity complex component 1
chr22_-_27920128 0.39 ENST00000415296.5
PITPNB
phosphatidylinositol transfer protein beta
chr18_-_21704763 0.36 ENST00000580981.5
ENST00000289119.7
ABHD3
abhydrolase domain containing 3, phospholipase
chr6_+_13574227 0.36 ENST00000680432.1
ENST00000681012.1
ENST00000397350.7
SIRT5
sirtuin 5
chr3_-_45915698 0.34 ENST00000539217.5
LZTFL1
leucine zipper transcription factor like 1
chrX_-_30889394 0.34 ENST00000288422.3
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
chr18_+_33578213 0.33 ENST00000681521.1
ENST00000269197.12
ASXL3
ASXL transcriptional regulator 3
chr9_+_136327424 0.33 ENST00000616132.4
GPSM1
G protein signaling modulator 1
chr15_-_80989792 0.29 ENST00000261758.6
ENST00000561312.5
MESD
mesoderm development LRP chaperone
chr19_-_23395418 0.29 ENST00000595533.1
ENST00000397082.2
ENST00000599743.5
ENST00000300619.12
ZNF91
zinc finger protein 91
chr12_-_123271089 0.28 ENST00000535979.5
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr14_-_23301474 0.27 ENST00000561437.1
ENST00000559942.5
ENST00000560913.1
ENST00000559314.5
ENST00000558058.5
PPP1R3E
protein phosphatase 1 regulatory subunit 3E
chr9_-_133376085 0.27 ENST00000485435.6
SURF4
surfeit 4
chr1_+_171090892 0.27 ENST00000367755.9
ENST00000479749.1
FMO3
flavin containing dimethylaniline monoxygenase 3
chr19_-_57559833 0.25 ENST00000457177.5
ZNF550
zinc finger protein 550
chr3_-_51968177 0.24 ENST00000466412.5
PCBP4
poly(rC) binding protein 4
chr22_-_17258235 0.23 ENST00000649310.1
ENST00000649746.1
ADA2
adenosine deaminase 2
chr3_-_13042419 0.21 ENST00000647458.1
IQSEC1
IQ motif and Sec7 domain ArfGEF 1
chr19_+_21020675 0.21 ENST00000595401.1
ZNF430
zinc finger protein 430
chr1_+_161749762 0.19 ENST00000367943.5
DUSP12
dual specificity phosphatase 12
chr17_-_51747788 0.15 ENST00000575097.1
CA10
carbonic anhydrase 10
chr17_-_74592283 0.14 ENST00000375352.1
CD300LD
CD300 molecule like family member d
chr19_+_21142058 0.13 ENST00000598331.1
ZNF431
zinc finger protein 431
chr19_-_38315749 0.13 ENST00000589247.1
ENST00000329420.12
ENST00000591784.5
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr22_+_22214765 0.12 ENST00000390287.2
IGLV10-54
immunoglobulin lambda variable 10-54
chr10_+_22928079 0.11 ENST00000447081.5
ARMC3
armadillo repeat containing 3
chr9_-_37592564 0.11 ENST00000544379.1
ENST00000321301.7
ENST00000377773.9
ENST00000401811.3
TOMM5
translocase of outer mitochondrial membrane 5
chr17_+_6070361 0.11 ENST00000317744.10
WSCD1
WSC domain containing 1
chr15_-_65611110 0.10 ENST00000567744.5
ENST00000568573.1
ENST00000562830.1
ENST00000569491.5
ENST00000561769.1
INTS14
integrator complex subunit 14
chr15_-_65611236 0.09 ENST00000420799.7
ENST00000313182.6
ENST00000431261.6
ENST00000652388.1
ENST00000442903.3
INTS14
integrator complex subunit 14
chr19_-_38315919 0.09 ENST00000591755.5
ENST00000337679.12
ENST00000339413.11
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr1_+_111449442 0.09 ENST00000369722.8
ENST00000483994.1
ATP5PB
ATP synthase peripheral stalk-membrane subunit b
chr9_-_133376111 0.09 ENST00000545297.5
ENST00000613129.4
ENST00000618229.4
SURF4
surfeit 4
chr19_-_14518383 0.07 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr19_-_43198079 0.07 ENST00000597374.5
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr3_-_51968387 0.06 ENST00000490063.5
ENST00000468324.5
ENST00000497653.5
ENST00000484633.5
PCBP4
poly(rC) binding protein 4
chr19_-_38315900 0.04 ENST00000592694.5
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr10_+_22928010 0.04 ENST00000376528.8
ARMC3
armadillo repeat containing 3
chr2_+_207711631 0.04 ENST00000295414.8
ENST00000420822.1
ENST00000339882.9
CCNYL1
cyclin Y like 1
chr14_+_22883220 0.01 ENST00000536884.1
ENST00000267396.9
REM2
RRAD and GEM like GTPase 2
chrX_-_49233309 0.01 ENST00000376251.5
ENST00000323022.10
ENST00000376265.2
CACNA1F
calcium voltage-gated channel subunit alpha1 F

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.7 9.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 1.5 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 13.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 1.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 3.3 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.6 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.2 3.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 3.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.2 0.9 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 0.7 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.2 0.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 0.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 1.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0036047 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.1 0.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.8 GO:0001878 response to yeast(GO:0001878)
0.1 0.5 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 0.3 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 2.2 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 1.0 GO:0015879 carnitine transport(GO:0015879)
0.0 2.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.2 GO:0035640 exploration behavior(GO:0035640)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 1.9 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 3.0 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.0 GO:0007566 embryo implantation(GO:0007566)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0097433 dense body(GO:0097433)
0.1 2.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 2.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 10.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 11.3 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0031091 platelet alpha granule(GO:0031091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.1 3.3 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.7 2.7 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 1.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 2.4 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.5 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.4 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 10.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.8 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 2.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 2.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 8.0 GO:0015631 tubulin binding(GO:0015631)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 3.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis