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avrg: Illumina Body Map 2 (GSE30611)

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Results for NR1H2

Z-value: 1.24

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
NR1H2
ENSG00000131408.15 NR1H2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg38_v1_chr19_+_50358571_50358611-0.241.9e-01Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_78063851 6.85 ENST00000281030.2
THRSP
thyroid hormone responsive
chr10_-_68527498 2.34 ENST00000609923.6
SLC25A16
solute carrier family 25 member 16
chr2_-_216081759 2.05 ENST00000265322.8
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr12_+_31962466 2.02 ENST00000381054.3
RESF1
retroelement silencing factor 1
chr4_-_70666884 1.70 ENST00000510614.5
JCHAIN
joining chain of multimeric IgA and IgM
chr4_-_70666961 1.64 ENST00000510437.5
JCHAIN
joining chain of multimeric IgA and IgM
chr9_-_104928139 1.56 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ABCA1
ATP binding cassette subfamily A member 1
chr17_-_17823593 1.48 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr19_+_15640880 1.47 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chr16_-_29745951 1.38 ENST00000329410.4
C16orf54
chromosome 16 open reading frame 54
chr12_+_56118241 1.37 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
ESYT1
ZC3H10
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr16_+_72008588 1.35 ENST00000572887.5
ENST00000219240.9
ENST00000574309.5
ENST00000576145.1
DHODH
dihydroorotate dehydrogenase (quinone)
chr19_+_17511835 1.31 ENST00000595782.1
PGLS
6-phosphogluconolactonase
chr19_+_15641280 1.30 ENST00000585846.1
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chrX_-_2929324 1.23 ENST00000381154.6
ARSD
arylsulfatase D
chr12_-_113403873 1.23 ENST00000552280.5
ENST00000257549.9
SDS
serine dehydratase
chr12_-_7018465 1.14 ENST00000261407.9
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr14_+_24130659 1.12 ENST00000267426.6
FITM1
fat storage inducing transmembrane protein 1
chr19_-_2042066 1.11 ENST00000591588.1
ENST00000591142.5
MKNK2
MAPK interacting serine/threonine kinase 2
chr8_-_28083920 1.09 ENST00000413272.7
NUGGC
nuclear GTPase, germinal center associated
chr4_-_2963327 1.08 ENST00000398071.4
ENST00000502735.5
ENST00000314262.10
ENST00000416614.7
NOP14
NOP14 nucleolar protein
chr11_+_87037956 1.03 ENST00000525018.5
TMEM135
transmembrane protein 135
chr4_+_107989714 1.03 ENST00000505878.4
ENST00000603302.5
ENST00000638621.1
HADH
hydroxyacyl-CoA dehydrogenase
chr19_-_38315749 1.01 ENST00000589247.1
ENST00000329420.12
ENST00000591784.5
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr4_-_83284752 1.01 ENST00000311461.7
ENST00000647002.2
ENST00000311469.9
COQ2
coenzyme Q2, polyprenyltransferase
chr11_+_32829903 0.99 ENST00000257836.4
PRRG4
proline rich and Gla domain 4
chr17_-_3691748 0.97 ENST00000552723.1
P2RX5
purinergic receptor P2X 5
chr11_+_87037915 0.96 ENST00000526733.5
ENST00000305494.6
ENST00000532959.5
TMEM135
transmembrane protein 135
chr11_-_118212885 0.95 ENST00000524477.5
JAML
junction adhesion molecule like
chr19_+_40586774 0.93 ENST00000594298.5
ENST00000597396.5
SHKBP1
SH3KBP1 binding protein 1
chr7_+_80624071 0.92 ENST00000438020.5
CD36
CD36 molecule
chr17_-_28368012 0.91 ENST00000555059.2
ENSG00000273171.1
novel protein, readthrough between VTN and SEBOX
chr12_-_46832370 0.90 ENST00000546940.1
SLC38A4
solute carrier family 38 member 4
chr16_-_68000549 0.90 ENST00000575510.5
DPEP2
dipeptidase 2
chr14_+_104579757 0.90 ENST00000331952.6
ENST00000557649.6
C14orf180
chromosome 14 open reading frame 180
chr1_-_161238196 0.90 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
NR1I3
nuclear receptor subfamily 1 group I member 3
chr19_-_38315900 0.90 ENST00000592694.5
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr10_-_70888546 0.89 ENST00000299299.4
PCBD1
pterin-4 alpha-carbinolamine dehydratase 1
chr15_+_81296913 0.89 ENST00000394652.6
IL16
interleukin 16
chr1_-_237004440 0.87 ENST00000464121.3
MT1HL1
metallothionein 1H like 1
chr12_+_56118396 0.86 ENST00000546903.1
ZC3H10
zinc finger CCCH-type containing 10
chr1_+_44808482 0.85 ENST00000450269.5
ENST00000409335.6
BTBD19
BTB domain containing 19
chr16_+_527698 0.84 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
CAPN15
calpain 15
chr19_-_6670151 0.83 ENST00000675206.1
TNFSF14
TNF superfamily member 14
chr11_+_119168705 0.82 ENST00000409109.6
ENST00000409991.5
ENST00000292199.6
NLRX1
NLR family member X1
chr11_+_119168188 0.81 ENST00000454811.5
ENST00000409265.8
ENST00000449394.5
NLRX1
NLR family member X1
chr16_-_3577375 0.78 ENST00000359128.10
NLRC3
NLR family CARD domain containing 3
chr16_-_3577288 0.78 ENST00000324659.12
NLRC3
NLR family CARD domain containing 3
chr19_-_6670117 0.77 ENST00000245912.7
TNFSF14
TNF superfamily member 14
chr19_+_17511606 0.76 ENST00000252603.7
ENST00000600923.5
PGLS
6-phosphogluconolactonase
chr19_-_38315919 0.76 ENST00000591755.5
ENST00000337679.12
ENST00000339413.11
YIF1B
Yip1 interacting factor homolog B, membrane trafficking protein
chr20_+_6007245 0.76 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr17_+_4771878 0.76 ENST00000270560.4
TM4SF5
transmembrane 4 L six family member 5
chr14_-_73996219 0.75 ENST00000553284.5
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
chr2_+_233195433 0.75 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase D
chr1_-_54623518 0.74 ENST00000302250.7
ENST00000371304.2
FAM151A
family with sequence similarity 151 member A
chr17_+_79022814 0.74 ENST00000578229.5
C1QTNF1
C1q and TNF related 1
chr4_-_39032343 0.73 ENST00000381938.4
TMEM156
transmembrane protein 156
chr19_-_35900532 0.72 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKBID
NFKB inhibitor delta
chr1_-_161238223 0.72 ENST00000515452.1
NR1I3
nuclear receptor subfamily 1 group I member 3
chrX_+_48683763 0.70 ENST00000376701.5
WAS
WASP actin nucleation promoting factor
chr15_-_88467353 0.68 ENST00000312475.5
ENST00000558531.1
MRPL46
mitochondrial ribosomal protein L46
chr1_-_161238163 0.68 ENST00000367982.8
NR1I3
nuclear receptor subfamily 1 group I member 3
chr15_-_60391127 0.68 ENST00000559350.5
ENST00000558986.5
ENST00000560389.5
ANXA2
annexin A2
chr17_-_8248035 0.68 ENST00000651323.1
CTC1
CST telomere replication complex component 1
chr19_+_16143678 0.68 ENST00000613986.4
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr2_-_164841410 0.68 ENST00000342193.8
ENST00000375458.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr17_-_17577440 0.68 ENST00000395782.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr11_+_35186820 0.68 ENST00000531110.6
ENST00000525685.6
CD44
CD44 molecule (Indian blood group)
chr16_-_11629210 0.68 ENST00000576036.5
LITAF
lipopolysaccharide induced TNF factor
chr16_+_30182969 0.67 ENST00000561815.5
CORO1A
coronin 1A
chr9_-_128067310 0.66 ENST00000373078.5
NAIF1
nuclear apoptosis inducing factor 1
chr5_+_76850001 0.65 ENST00000513010.5
ENST00000317593.9
S100Z
S100 calcium binding protein Z
chr2_-_164841208 0.64 ENST00000439313.5
COBLL1
cordon-bleu WH2 repeat protein like 1
chr1_-_19799872 0.63 ENST00000294543.11
TMCO4
transmembrane and coiled-coil domains 4
chr1_-_153977623 0.63 ENST00000356648.5
JTB
jumping translocation breakpoint
chr2_-_178804623 0.63 ENST00000359218.10
ENST00000342175.11
TTN
titin
chr2_-_74472643 0.63 ENST00000258105.8
ENST00000409710.1
MRPL53
mitochondrial ribosomal protein L53
chr1_+_10399054 0.62 ENST00000270776.13
ENST00000483936.5
PGD
phosphogluconate dehydrogenase
chr3_+_39329700 0.62 ENST00000326306.5
CCR8
C-C motif chemokine receptor 8
chr8_-_92103270 0.62 ENST00000518832.1
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr12_-_55688891 0.61 ENST00000557555.2
ITGA7
integrin subunit alpha 7
chr11_-_111379268 0.61 ENST00000393067.8
POU2AF1
POU class 2 homeobox associating factor 1
chr1_+_209827964 0.61 ENST00000491415.7
UTP25
UTP25 small subunit processor component
chr3_+_39329764 0.61 ENST00000414803.1
CCR8
C-C motif chemokine receptor 8
chr7_+_100539188 0.59 ENST00000300176.9
AGFG2
ArfGAP with FG repeats 2
chr11_+_810227 0.58 ENST00000530398.1
RPLP2
ribosomal protein lateral stalk subunit P2
chr11_-_62754141 0.58 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
ZBTB3
zinc finger and BTB domain containing 3
chr20_+_36091803 0.57 ENST00000432589.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr11_+_10305065 0.57 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
ADM
adrenomedullin
chr12_-_56300358 0.57 ENST00000550655.5
ENST00000548567.5
ENST00000551430.6
CS
citrate synthase
chr12_-_213338 0.55 ENST00000424061.6
SLC6A12
solute carrier family 6 member 12
chr11_+_87037820 0.54 ENST00000340353.11
TMEM135
transmembrane protein 135
chr9_+_92974476 0.54 ENST00000337352.10
FGD3
FYVE, RhoGEF and PH domain containing 3
chr11_+_67403887 0.52 ENST00000526387.5
TBC1D10C
TBC1 domain family member 10C
chr2_+_32165841 0.52 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
SLC30A6
solute carrier family 30 member 6
chr11_+_844406 0.51 ENST00000397404.5
TSPAN4
tetraspanin 4
chr18_-_69956924 0.50 ENST00000581982.5
ENST00000280200.8
CD226
CD226 molecule
chr5_+_80488094 0.50 ENST00000282226.5
FAM151B
family with sequence similarity 151 member B
chr16_+_4624811 0.49 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
MGRN1
mahogunin ring finger 1
chr19_+_1077394 0.49 ENST00000590577.2
ARHGAP45
Rho GTPase activating protein 45
chr17_+_28720552 0.49 ENST00000472628.1
ENST00000578181.1
RPL23A
ribosomal protein L23a
chr21_-_42010327 0.48 ENST00000398505.7
ENST00000449949.5
ENST00000310826.10
ENST00000398499.5
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chr1_-_153977260 0.48 ENST00000428469.1
JTB
jumping translocation breakpoint
chr11_-_82900406 0.48 ENST00000313010.8
ENST00000393399.6
ENST00000680437.1
PRCP
prolylcarboxypeptidase
chr15_+_88467692 0.48 ENST00000325844.9
ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr2_+_206765578 0.48 ENST00000403094.3
ENST00000402774.8
FASTKD2
FAST kinase domains 2
chr19_+_15737985 0.47 ENST00000641646.1
OR10H3
olfactory receptor family 10 subfamily H member 3
chr1_+_179294173 0.47 ENST00000426956.1
SOAT1
sterol O-acyltransferase 1
chr12_-_6568256 0.47 ENST00000382421.7
ENST00000545200.5
ENST00000399466.6
ENST00000322166.10
ENST00000536124.5
ENST00000540228.1
ENST00000542867.5
ENST00000545492.5
ENST00000545915.5
ENST00000620535.4
ENST00000617555.4
NOP2
NOP2 nucleolar protein
chr5_-_181238195 0.47 ENST00000509148.1
RACK1
receptor for activated C kinase 1
chr12_-_213656 0.46 ENST00000359674.8
SLC6A12
solute carrier family 6 member 12
chr12_-_214146 0.46 ENST00000684302.1
SLC6A12
solute carrier family 6 member 12
chr17_+_8310220 0.45 ENST00000583529.1
ENST00000361926.8
ARHGEF15
Rho guanine nucleotide exchange factor 15
chr2_+_27032938 0.45 ENST00000238788.14
ENST00000404032.7
TMEM214
transmembrane protein 214
chr17_+_79022908 0.44 ENST00000354124.7
ENST00000580454.5
C1QTNF1
C1q and TNF related 1
chr14_-_80315876 0.44 ENST00000553594.1
DIO2
iodothyronine deiodinase 2
chr14_-_94504222 0.44 ENST00000556881.5
SERPINA12
serpin family A member 12
chr16_-_31094727 0.43 ENST00000300851.10
ENST00000394975.3
VKORC1
vitamin K epoxide reductase complex subunit 1
chr7_+_2647703 0.43 ENST00000403167.5
TTYH3
tweety family member 3
chr12_+_51888217 0.43 ENST00000340970.8
ANKRD33
ankyrin repeat domain 33
chr11_+_119168360 0.43 ENST00000422249.5
NLRX1
NLR family member X1
chr19_-_54339146 0.43 ENST00000291759.5
LILRA4
leukocyte immunoglobulin like receptor A4
chr6_-_30672984 0.42 ENST00000415603.1
ENST00000376442.8
DHX16
DEAH-box helicase 16
chr10_+_99732211 0.42 ENST00000370476.10
ENST00000370472.4
CUTC
cutC copper transporter
chr19_-_45370384 0.42 ENST00000485403.6
ENST00000586856.1
ENST00000586131.6
ENST00000391945.10
ENST00000684407.1
ENST00000391944.8
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit
chr22_+_35717872 0.41 ENST00000249044.2
APOL5
apolipoprotein L5
chr21_-_44920892 0.41 ENST00000397846.7
ENST00000652462.1
ENST00000302347.10
ENST00000524251.1
ITGB2
integrin subunit beta 2
chr1_+_26177482 0.41 ENST00000361530.11
ENST00000374253.9
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr7_-_75073774 0.41 ENST00000610322.5
RCC1L
RCC1 like
chr19_-_48617797 0.40 ENST00000546623.5
ENST00000084795.9
RPL18
ribosomal protein L18
chr11_+_1850896 0.40 ENST00000676039.1
LSP1
lymphocyte specific protein 1
chr17_-_81637049 0.40 ENST00000374747.9
ENST00000331134.11
NPLOC4
NPL4 homolog, ubiquitin recognition factor
chr19_-_17255448 0.40 ENST00000594059.1
ENSG00000269095.1
novel protein
chr8_+_38207586 0.40 ENST00000521311.1
BAG4
BAG cochaperone 4
chr3_-_127590707 0.40 ENST00000296210.11
ENST00000355552.8
TPRA1
transmembrane protein adipocyte associated 1
chr2_+_216081866 0.39 ENST00000433112.5
ENST00000454545.5
ENST00000295658.8
ENST00000455479.5
ENST00000406027.2
ENST00000437356.7
TMEM169
transmembrane protein 169
chr19_-_57916603 0.39 ENST00000599251.1
ENST00000598526.5
ZNF417
zinc finger protein 417
chr14_+_20223710 0.38 ENST00000315519.3
OR11H6
olfactory receptor family 11 subfamily H member 6
chr16_+_21612071 0.38 ENST00000562961.1
METTL9
methyltransferase like 9
chr1_+_152786214 0.38 ENST00000368771.1
ENST00000368770.4
LCE1E
late cornified envelope 1E
chrX_+_108091752 0.38 ENST00000457035.5
ENST00000372232.8
ATG4A
autophagy related 4A cysteine peptidase
chr4_-_39366342 0.38 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
RFC1
replication factor C subunit 1
chr1_+_23791203 0.38 ENST00000374503.7
ENST00000374502.7
LYPLA2
lysophospholipase 2
chr4_+_102869332 0.37 ENST00000503643.1
CISD2
CDGSH iron sulfur domain 2
chr11_-_6027741 0.36 ENST00000641938.1
OR56A1
olfactory receptor family 56 subfamily A member 1
chr3_+_101561833 0.36 ENST00000309922.7
TRMT10C
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr2_-_218282098 0.36 ENST00000425694.5
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr12_+_51888083 0.36 ENST00000301190.11
ANKRD33
ankyrin repeat domain 33
chr3_-_114454683 0.36 ENST00000470311.5
ZBTB20
zinc finger and BTB domain containing 20
chr19_+_15673069 0.36 ENST00000550308.6
ENST00000551607.5
CYP4F12
cytochrome P450 family 4 subfamily F member 12
chr21_-_44920918 0.35 ENST00000522688.5
ITGB2
integrin subunit beta 2
chr17_-_67996428 0.35 ENST00000580729.3
C17orf58
chromosome 17 open reading frame 58
chr12_-_214082 0.35 ENST00000535347.5
ENST00000536824.5
SLC6A12
solute carrier family 6 member 12
chr2_+_167187364 0.35 ENST00000672671.1
XIRP2
xin actin binding repeat containing 2
chr3_+_101561926 0.35 ENST00000495642.1
TRMT10C
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr19_+_8418386 0.35 ENST00000602117.1
MARCHF2
membrane associated ring-CH-type finger 2
chr12_+_123458092 0.35 ENST00000526639.3
SNRNP35
small nuclear ribonucleoprotein U11/U12 subunit 35
chr11_+_62885177 0.34 ENST00000539507.1
SLC3A2
solute carrier family 3 member 2
chr4_+_38867789 0.34 ENST00000358869.5
FAM114A1
family with sequence similarity 114 member A1
chr5_+_172983763 0.34 ENST00000519374.6
ENST00000519911.5
ATP6V0E1
ATPase H+ transporting V0 subunit e1
chr1_+_35869750 0.34 ENST00000373206.5
AGO1
argonaute RISC component 1
chr14_-_73458519 0.34 ENST00000356296.8
ENST00000557597.5
ENST00000554394.5
ENST00000555238.6
ENST00000555987.5
ENST00000555394.5
ENST00000554546.5
NUMB
NUMB endocytic adaptor protein
chr7_+_16661182 0.33 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
BZW2
basic leucine zipper and W2 domains 2
chr8_-_28083850 0.33 ENST00000418860.1
NUGGC
nuclear GTPase, germinal center associated
chr21_+_42199686 0.33 ENST00000398457.6
ABCG1
ATP binding cassette subfamily G member 1
chr19_+_57849834 0.32 ENST00000339656.8
ENST00000423137.1
ZNF587
zinc finger protein 587
chr3_+_46880242 0.32 ENST00000418619.5
PTH1R
parathyroid hormone 1 receptor
chr1_+_23791138 0.32 ENST00000374514.8
ENST00000420982.5
ENST00000374505.6
LYPLA2
lysophospholipase 2
chr12_+_53241884 0.32 ENST00000635789.1
ENSG00000283536.2
novel protein
chr22_-_33572227 0.32 ENST00000674780.1
LARGE1
LARGE xylosyl- and glucuronyltransferase 1
chr14_-_59484317 0.31 ENST00000247194.9
L3HYPDH
trans-L-3-hydroxyproline dehydratase
chr19_+_52274443 0.31 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
ZNF766
zinc finger protein 766
chr1_+_156369202 0.31 ENST00000537040.6
RHBG
Rh family B glycoprotein
chr14_-_70359630 0.30 ENST00000389912.7
COX16
cytochrome c oxidase assembly factor COX16
chrX_-_72714181 0.30 ENST00000339490.7
ENST00000541944.5
ENST00000373539.3
PHKA1
phosphorylase kinase regulatory subunit alpha 1
chr11_+_827248 0.30 ENST00000527089.5
ENST00000530183.1
CRACR2B
calcium release activated channel regulator 2B
chr17_+_78187317 0.30 ENST00000409257.9
ENST00000591256.5
ENST00000589256.5
ENST00000588800.5
ENST00000591952.5
ENST00000327898.9
ENST00000586542.5
ENST00000586731.1
AFMID
arylformamidase
chr16_+_71626149 0.29 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr9_-_113397356 0.29 ENST00000452726.1
ALAD
aminolevulinate dehydratase
chrX_+_108091665 0.29 ENST00000345734.7
ATG4A
autophagy related 4A cysteine peptidase
chr16_+_53099100 0.29 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr1_+_223701607 0.29 ENST00000434648.5
CAPN2
calpain 2
chr7_+_45027634 0.28 ENST00000381112.7
ENST00000474617.1
CCM2
CCM2 scaffold protein
chr1_+_13303539 0.28 ENST00000437300.2
PRAMEF33
PRAME family member 33
chr9_-_41189310 0.28 ENST00000456520.5
ENST00000377391.8
ENST00000613716.4
ENST00000617933.1
CBWD6
COBW domain containing 6
chr12_+_6970904 0.28 ENST00000599672.6
ENST00000539196.2
EMG1
EMG1 N1-specific pseudouridine methyltransferase
chr9_+_68241854 0.28 ENST00000616550.4
ENST00000618217.4
ENST00000377342.9
ENST00000478048.5
ENST00000360171.11
CBWD3
COBW domain containing 3
chr19_+_54105923 0.28 ENST00000420296.1
NDUFA3
NADH:ubiquinone oxidoreductase subunit A3
chr1_-_153946652 0.27 ENST00000361217.9
DENND4B
DENN domain containing 4B
chr21_-_44920855 0.27 ENST00000397854.7
ITGB2
integrin subunit beta 2
chr20_+_19758245 0.27 ENST00000255006.12
RIN2
Ras and Rab interactor 2
chr7_-_138679045 0.27 ENST00000419765.4
SVOPL
SVOP like
chr2_+_167187283 0.26 ENST00000409605.1
ENST00000409273.6
XIRP2
xin actin binding repeat containing 2
chr16_+_28863023 0.26 ENST00000566209.1
SH2B1
SH2B adaptor protein 1
chr7_-_73738831 0.26 ENST00000395147.9
ENST00000437775.7
ABHD11
abhydrolase domain containing 11
chr1_-_12945416 0.26 ENST00000415464.6
PRAMEF6
PRAME family member 6
chr14_-_73458248 0.26 ENST00000555307.5
ENST00000554818.5
NUMB
NUMB endocytic adaptor protein
chr4_+_38867677 0.26 ENST00000510213.5
ENST00000515037.5
FAM114A1
family with sequence similarity 114 member A1
chr17_-_78187036 0.26 ENST00000590862.5
ENST00000590430.5
ENST00000301634.12
ENST00000586613.1
TK1
thymidine kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.5 2.1 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.4 2.7 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 1.3 GO:1903576 'de novo' UMP biosynthetic process(GO:0044205) response to L-arginine(GO:1903576)
0.4 1.6 GO:0015917 aminophospholipid transport(GO:0015917)
0.4 1.1 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 1.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 3.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 6.9 GO:0006853 carnitine shuttle(GO:0006853)
0.2 0.7 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.2 1.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2 0.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.7 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.2 0.7 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2 1.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 2.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.7 GO:0032796 uropod organization(GO:0032796)
0.1 0.4 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.8 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 1.0 GO:0035696 monocyte extravasation(GO:0035696)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.9 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0070541 response to platinum ion(GO:0070541)
0.1 0.7 GO:0051697 protein delipidation(GO:0051697)
0.1 0.5 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.8 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.8 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.9 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.7 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.2 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 0.7 GO:0048539 bone marrow development(GO:0048539)
0.1 0.5 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.5 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.1 0.6 GO:0097646 progesterone biosynthetic process(GO:0006701) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0060356 leucine import(GO:0060356)
0.0 0.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 2.2 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.9 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.8 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 1.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.8 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 0.3 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 2.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 2.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 1.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
0.4 1.1 GO:0030689 Noc complex(GO:0030689)
0.2 0.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.1 0.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 1.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 0.4 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.1 0.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 0.5 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 4.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.7 2.1 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5 1.6 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.5 2.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.5 3.3 GO:0019862 IgA binding(GO:0019862)
0.4 1.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.4 2.3 GO:0004882 androgen receptor activity(GO:0004882)
0.3 1.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.3 1.3 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2 0.7 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 0.4 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.2 0.6 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 0.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 1.5 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.5 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.7 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.4 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 0.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 1.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 1.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.2 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 1.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.3 GO:0015297 antiporter activity(GO:0015297)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 3.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 2.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation