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avrg: Illumina Body Map 2 (GSE30611)
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Results for NR4A3
Z-value: 1.91
Motif logo
Transcription factors associated with NR4A3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NR4A3
|
ENSG00000119508.18 | NR4A3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR4A3 | hg38_v1_chr9_+_99821846_99821862 | -0.15 | 4.2e-01 | Click! |
Activity profile of NR4A3 motif
Sorted Z-values of NR4A3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of NR4A3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.3 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 1.2 | 3.5 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.9 | 3.7 | GO:0015744 | succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) |
| 0.9 | 8.0 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
| 0.9 | 2.6 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.8 | 2.5 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.8 | 2.5 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 0.8 | 2.3 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.7 | 2.2 | GO:0060578 | subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) |
| 0.7 | 2.1 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.7 | 2.1 | GO:0072361 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) |
| 0.7 | 4.8 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 0.6 | 1.9 | GO:0016999 | antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) |
| 0.6 | 6.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.6 | 3.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.6 | 3.5 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.6 | 1.7 | GO:0034031 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
| 0.5 | 3.2 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.5 | 5.7 | GO:0010269 | response to selenium ion(GO:0010269) |
| 0.5 | 3.0 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.5 | 1.8 | GO:0003165 | Purkinje myocyte development(GO:0003165) |
| 0.5 | 1.4 | GO:2000974 | auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.5 | 1.4 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.4 | 3.6 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.4 | 1.3 | GO:1904199 | positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736) |
| 0.4 | 0.4 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.4 | 1.2 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.4 | 1.6 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.4 | 2.4 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.4 | 1.9 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.4 | 1.5 | GO:0003285 | septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054) |
| 0.3 | 5.6 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.3 | 1.0 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.3 | 1.0 | GO:0019483 | beta-alanine biosynthetic process(GO:0019483) |
| 0.3 | 2.0 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.3 | 1.0 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) activation of protein kinase C activity(GO:1990051) regulation of glutamine transport(GO:2000485) |
| 0.3 | 1.0 | GO:1905237 | response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025) |
| 0.3 | 1.9 | GO:1900106 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.3 | 1.6 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 0.3 | 1.9 | GO:2000983 | regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984) |
| 0.3 | 0.9 | GO:0061445 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) |
| 0.3 | 6.7 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.3 | 1.2 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
| 0.3 | 0.6 | GO:0043605 | cellular amide catabolic process(GO:0043605) |
| 0.3 | 3.3 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.3 | 10.7 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.3 | 2.0 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.3 | 0.8 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.2 | 1.2 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.2 | 1.0 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.2 | 1.4 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.2 | 1.6 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.2 | 5.1 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.2 | 0.7 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
| 0.2 | 1.8 | GO:0060694 | regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230) |
| 0.2 | 0.9 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.2 | 5.0 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.2 | 2.2 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.2 | 1.1 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.2 | 1.6 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.2 | 1.6 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.2 | 0.8 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.2 | 1.7 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.2 | 1.5 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.2 | 0.6 | GO:0048058 | compound eye corneal lens development(GO:0048058) |
| 0.2 | 0.6 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.2 | 2.2 | GO:1902221 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.2 | 0.9 | GO:0030806 | negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) |
| 0.2 | 0.5 | GO:0035565 | regulation of pronephros size(GO:0035565) |
| 0.2 | 0.5 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 0.2 | 0.5 | GO:0060003 | copper ion export(GO:0060003) |
| 0.2 | 1.7 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.2 | 2.9 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 0.5 | GO:0015881 | creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598) |
| 0.2 | 1.0 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.2 | 1.1 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.2 | 0.5 | GO:0097272 | ammonia homeostasis(GO:0097272) |
| 0.2 | 1.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 0.9 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
| 0.2 | 0.8 | GO:0006311 | meiotic gene conversion(GO:0006311) |
| 0.2 | 0.5 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.2 | 1.7 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.7 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.1 | 1.0 | GO:0072156 | distal tubule morphogenesis(GO:0072156) |
| 0.1 | 0.4 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 0.1 | 0.6 | GO:2000733 | regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734) |
| 0.1 | 1.3 | GO:0036022 | limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) |
| 0.1 | 0.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.6 | GO:0085032 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.1 | 0.4 | GO:0090410 | malonate catabolic process(GO:0090410) |
| 0.1 | 1.7 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.1 | 9.3 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.1 | 1.2 | GO:0086029 | Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068) |
| 0.1 | 0.5 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.1 | 1.0 | GO:0019556 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.1 | 0.8 | GO:1901523 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 0.1 | 2.7 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.1 | 0.4 | GO:0002426 | immunoglobulin production in mucosal tissue(GO:0002426) |
| 0.1 | 0.5 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.1 | 0.7 | GO:1904398 | positive regulation of neuromuscular junction development(GO:1904398) |
| 0.1 | 1.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 0.9 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.1 | 2.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 1.6 | GO:0036309 | protein localization to M-band(GO:0036309) |
| 0.1 | 1.0 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.1 | 2.5 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.1 | 1.2 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.1 | 1.1 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.1 | 0.5 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 0.1 | 1.3 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 1.3 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.1 | 0.7 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.1 | 3.7 | GO:0017144 | drug metabolic process(GO:0017144) |
| 0.1 | 0.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 2.0 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.1 | 1.4 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.7 | GO:1904386 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
| 0.1 | 0.5 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.1 | 0.4 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.6 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.1 | 2.2 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.1 | 0.7 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 0.5 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.1 | 2.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.7 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 1.8 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.1 | 0.7 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.1 | 1.7 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.1 | 1.0 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.8 | GO:0044211 | CTP salvage(GO:0044211) |
| 0.1 | 1.0 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.1 | 0.5 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.1 | 0.5 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.1 | 1.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.3 | GO:1902824 | positive regulation of late endosome to lysosome transport(GO:1902824) |
| 0.1 | 0.4 | GO:0030961 | peptidyl-arginine hydroxylation(GO:0030961) |
| 0.1 | 3.3 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.1 | 0.3 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.1 | 0.7 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
| 0.1 | 0.6 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.1 | 0.3 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.1 | 1.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 2.9 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.1 | 2.0 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 0.3 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.1 | 0.5 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 3.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.5 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 0.3 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.1 | 0.3 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.1 | 0.7 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.1 | 0.8 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.1 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.1 | 2.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.7 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.1 | 0.3 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
| 0.1 | 0.2 | GO:0032048 | phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) |
| 0.1 | 0.7 | GO:0010755 | regulation of plasminogen activation(GO:0010755) positive regulation of plasminogen activation(GO:0010756) |
| 0.1 | 4.0 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.1 | 0.2 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 2.7 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 1.8 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.1 | 3.2 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.1 | 0.3 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.1 | 1.1 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.1 | 1.4 | GO:0072189 | ureter development(GO:0072189) |
| 0.1 | 2.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.1 | 0.3 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.1 | 1.1 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.0 | 0.2 | GO:0045229 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.0 | 0.6 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.0 | 2.0 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 1.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 0.3 | GO:0045713 | low-density lipoprotein particle receptor biosynthetic process(GO:0045713) |
| 0.0 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 1.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.3 | GO:0006701 | progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011) |
| 0.0 | 2.6 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.0 | 0.6 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 1.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.0 | 1.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.0 | 0.8 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.0 | 0.8 | GO:1902548 | negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548) |
| 0.0 | 0.4 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.0 | 0.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.0 | 0.3 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.0 | 0.5 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.0 | 0.3 | GO:1901162 | primary amino compound biosynthetic process(GO:1901162) |
| 0.0 | 0.3 | GO:0032960 | regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
| 0.0 | 0.6 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.0 | 0.7 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.4 | GO:0060579 | ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
| 0.0 | 0.9 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 1.8 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 1.0 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.0 | 0.6 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 1.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.0 | 0.7 | GO:0001946 | lymphangiogenesis(GO:0001946) |
| 0.0 | 2.5 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.6 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.0 | 0.5 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.0 | 0.3 | GO:0035745 | T-helper 2 cell cytokine production(GO:0035745) |
| 0.0 | 4.4 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.1 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 0.0 | 0.1 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 0.0 | 2.9 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.5 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
| 0.0 | 0.3 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.0 | 0.3 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
| 0.0 | 1.8 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.3 | GO:0001553 | luteinization(GO:0001553) |
| 0.0 | 1.8 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.1 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 0.0 | 0.5 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.0 | 1.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.6 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.4 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:1902988 | regulation of neuronal signal transduction(GO:1902847) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.0 | 1.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.7 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.0 | 0.3 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 2.6 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 0.6 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.0 | 0.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 1.1 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.0 | 2.1 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.4 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.0 | 1.0 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 0.0 | 0.3 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.0 | 0.1 | GO:0007343 | egg activation(GO:0007343) female pronucleus assembly(GO:0035038) |
| 0.0 | 1.0 | GO:0002828 | regulation of type 2 immune response(GO:0002828) |
| 0.0 | 0.9 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.1 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.0 | 0.3 | GO:0045821 | positive regulation of glycolytic process(GO:0045821) |
| 0.0 | 0.3 | GO:0008212 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.0 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.0 | 0.3 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.0 | 0.5 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.0 | 1.1 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.0 | 0.1 | GO:0007060 | male meiosis chromosome segregation(GO:0007060) |
| 0.0 | 1.5 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
| 0.0 | 0.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.2 | GO:0051583 | dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494) |
| 0.0 | 0.0 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.0 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.8 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.2 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.5 | GO:2000810 | regulation of bicellular tight junction assembly(GO:2000810) |
| 0.0 | 0.2 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 1.1 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.1 | GO:1902559 | 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559) |
| 0.0 | 0.4 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 0.2 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.9 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 0.4 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.3 | GO:0060259 | regulation of feeding behavior(GO:0060259) |
| 0.0 | 2.4 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.3 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.5 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 1.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 2.0 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.4 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 0.1 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.0 | 1.2 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.2 | GO:0036028 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.7 | 8.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.7 | 2.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.6 | 1.9 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.6 | 3.5 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.4 | 2.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.4 | 2.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.4 | 5.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.4 | 3.4 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.4 | 8.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.4 | 1.1 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.3 | 1.0 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.2 | 3.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.2 | 4.0 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.2 | 1.7 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.2 | 5.0 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.2 | 2.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 4.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 1.8 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.2 | 0.9 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.2 | 0.9 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.1 | 1.6 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 0.5 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 1.4 | GO:0016589 | NURF complex(GO:0016589) |
| 0.1 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 7.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.4 | GO:0071920 | cleavage body(GO:0071920) |
| 0.1 | 3.0 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 2.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 4.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.3 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.1 | 0.2 | GO:0036457 | keratohyalin granule(GO:0036457) |
| 0.1 | 2.1 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.5 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.1 | 1.9 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 9.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 0.4 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.1 | 4.8 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 1.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 1.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.8 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 2.6 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.4 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 0.9 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.1 | 0.4 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.2 | GO:0044753 | amphisome(GO:0044753) |
| 0.0 | 1.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 1.8 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 1.6 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.3 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 0.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.0 | 0.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.8 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.0 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.2 | GO:0070470 | plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470) |
| 0.0 | 10.7 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 1.3 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.0 | 0.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 22.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 4.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 0.1 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 0.2 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 0.3 | GO:0097486 | late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486) |
| 0.0 | 1.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 9.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.1 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.0 | 0.4 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 1.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 5.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.0 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 2.3 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 4.2 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 1.3 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.3 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 7.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0033011 | perinuclear theca(GO:0033011) |
| 0.0 | 0.7 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.3 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.1 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.0 | 0.2 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 0.0 | 1.3 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 3.9 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 3.7 | GO:0044445 | cytosolic part(GO:0044445) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 1.3 | 3.8 | GO:0033791 | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity(GO:0033791) |
| 1.2 | 4.8 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.9 | 3.7 | GO:0015141 | succinate transmembrane transporter activity(GO:0015141) |
| 0.9 | 7.3 | GO:0035473 | lipase binding(GO:0035473) |
| 0.7 | 8.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.6 | 3.9 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.6 | 2.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
| 0.5 | 2.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.5 | 1.6 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.5 | 4.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.5 | 1.4 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990) |
| 0.4 | 3.1 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.4 | 1.7 | GO:0031716 | calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716) |
| 0.4 | 1.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.4 | 2.3 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.4 | 2.6 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.4 | 2.2 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.3 | 1.0 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.3 | 3.2 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.3 | 1.2 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.3 | 1.2 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 0.3 | 1.1 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.3 | 3.6 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.3 | 1.9 | GO:0097001 | sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001) |
| 0.3 | 0.8 | GO:0097259 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.3 | 1.9 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 3.1 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.3 | 2.0 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.3 | 3.5 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 1.5 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.2 | 1.0 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.2 | 0.9 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.2 | 0.7 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.2 | 3.0 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.2 | 0.9 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.2 | 0.9 | GO:0004341 | gluconolactonase activity(GO:0004341) |
| 0.2 | 0.4 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.2 | 2.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.2 | 0.6 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.2 | 2.0 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.2 | 1.5 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.2 | 1.8 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.2 | 3.8 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.2 | 3.8 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.2 | 1.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 1.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.2 | 0.5 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 0.2 | 0.5 | GO:0005308 | creatine transmembrane transporter activity(GO:0005308) |
| 0.2 | 1.0 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.2 | 0.8 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.2 | 1.4 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 7.0 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) |
| 0.1 | 0.6 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.1 | 0.4 | GO:0090409 | malonyl-CoA synthetase activity(GO:0090409) |
| 0.1 | 1.8 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 1.0 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 1.0 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.1 | 0.4 | GO:0047225 | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225) |
| 0.1 | 0.4 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.1 | 0.9 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 0.7 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.1 | 0.3 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.1 | 1.7 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.7 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.1 | 1.1 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 0.9 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.1 | 2.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 2.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.1 | 2.1 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.1 | 2.9 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 2.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 1.0 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.9 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 0.8 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 1.4 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.1 | 0.3 | GO:0050333 | thiamin-triphosphatase activity(GO:0050333) |
| 0.1 | 0.8 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.1 | 1.1 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.1 | 0.3 | GO:0043849 | Ras palmitoyltransferase activity(GO:0043849) |
| 0.1 | 1.6 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.1 | 2.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 2.9 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.2 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.1 | 2.9 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 1.0 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.1 | 1.4 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 0.6 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.1 | 2.5 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.1 | 1.7 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 0.2 | GO:0016794 | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794) |
| 0.1 | 0.4 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 0.1 | 1.1 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.5 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 1.6 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 0.7 | GO:0005497 | androgen binding(GO:0005497) benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.9 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 11.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.8 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 2.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.1 | 2.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.1 | 0.7 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 2.2 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.1 | 1.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 0.8 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.1 | 2.6 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.1 | 0.3 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 1.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.3 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
| 0.1 | 0.5 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.1 | 1.6 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 2.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 8.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 0.7 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 0.5 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 2.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.4 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 0.0 | 3.4 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.2 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.0 | 0.2 | GO:0005334 | norepinephrine:sodium symporter activity(GO:0005334) |
| 0.0 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 2.1 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.1 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.0 | 0.3 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 2.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.4 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 1.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.9 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.5 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.3 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 1.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 1.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.5 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 0.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 5.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.6 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 1.9 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.5 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.3 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 0.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.0 | 2.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.4 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.2 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.0 | 4.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.0 | 3.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.3 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.0 | 4.4 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.4 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 1.0 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 1.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.6 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.0 | 1.3 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 1.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 2.6 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 1.0 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 0.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 1.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.2 | GO:0030883 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.6 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.7 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 3.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 2.7 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.0 | 0.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.7 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.4 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.0 | 2.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.1 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.1 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.0 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.1 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 0.2 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
| 0.0 | 0.6 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.7 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.6 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.0 | 1.4 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 0.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.4 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.9 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.4 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 0.0 | 0.7 | GO:0004532 | exoribonuclease activity(GO:0004532) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.7 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.1 | 5.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 28.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 3.7 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.1 | 2.3 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 2.2 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 4.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 4.1 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 3.5 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 2.2 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 2.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 2.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 2.2 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 5.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 2.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 2.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 1.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 1.4 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 0.6 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.5 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.6 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 4.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.3 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.3 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.1 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 5.4 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.7 | PID MTOR 4PATHWAY | mTOR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 10.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.3 | 8.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.3 | 7.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 0.2 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.2 | 2.6 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 15.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 3.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.2 | 3.8 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 1.8 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 2.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 3.0 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 7.3 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 3.9 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 2.4 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 3.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 2.1 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.2 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 3.6 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 7.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 1.7 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.2 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 2.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 0.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 2.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 4.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 1.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 2.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 0.8 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.1 | 5.5 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 2.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 6.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 1.3 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 1.0 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 2.2 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.4 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 1.0 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.4 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 2.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 1.7 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.3 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.6 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.8 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 2.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 6.7 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 4.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.9 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.0 | 0.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 2.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.5 | REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 0.0 | 1.1 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.0 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 2.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.2 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.3 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |