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avrg: Illumina Body Map 2 (GSE30611)

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Results for OLIG1

Z-value: 1.71

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Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
OLIG1
ENSG00000184221.13 OLIG1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG1hg38_v1_chr21_+_33070133_330701490.336.2e-02Click!

Activity profile of OLIG1 motif

Sorted Z-values of OLIG1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_157439403 4.95 ENST00000418920.5
CYTIP
cytohesin 1 interacting protein
chr14_-_106038355 4.20 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr14_-_106803221 3.78 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr2_-_181680490 3.52 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr2_-_157488829 3.52 ENST00000435117.1
ENST00000439355.5
CYTIP
cytohesin 1 interacting protein
chr19_-_11339573 3.23 ENST00000222120.8
RAB3D
RAB3D, member RAS oncogene family
chr11_+_65638085 3.05 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr11_+_118304721 2.89 ENST00000361763.9
CD3E
CD3e molecule
chr11_+_118304881 2.85 ENST00000528600.1
CD3E
CD3e molecule
chr5_-_170297746 2.82 ENST00000046794.10
LCP2
lymphocyte cytosolic protein 2
chr2_+_89947508 2.77 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr4_-_38782970 2.73 ENST00000502321.5
ENST00000308973.9
ENST00000613579.4
ENST00000361424.6
ENST00000622002.4
TLR10
toll like receptor 10
chr11_+_60396451 2.70 ENST00000300187.11
ENST00000526375.5
ENST00000531783.5
MS4A14
membrane spanning 4-domains A14
chr12_+_6789508 2.70 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4
CD4 molecule
chr7_+_142618821 2.63 ENST00000390393.3
TRBV19
T cell receptor beta variable 19
chr7_-_38363476 2.54 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr19_+_18097763 2.51 ENST00000262811.10
MAST3
microtubule associated serine/threonine kinase 3
chr19_-_54364983 2.43 ENST00000434277.6
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr5_+_157180816 2.42 ENST00000422843.8
ITK
IL2 inducible T cell kinase
chr12_-_7936177 2.39 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr2_+_190927649 2.34 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr11_+_60396435 2.18 ENST00000395005.6
MS4A14
membrane spanning 4-domains A14
chr1_+_9651723 2.15 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr22_+_37282464 2.12 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
CYTH4
cytohesin 4
chr1_-_160579439 2.11 ENST00000368054.8
ENST00000368048.7
ENST00000311224.8
ENST00000368051.3
ENST00000534968.5
CD84
CD84 molecule
chr14_-_106025628 2.11 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr6_+_31586124 2.10 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr16_+_11965193 2.10 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr15_+_88635626 2.06 ENST00000379224.10
ISG20
interferon stimulated exonuclease gene 20
chr8_-_100712761 2.06 ENST00000517403.5
PABPC1
poly(A) binding protein cytoplasmic 1
chr2_-_174598206 2.06 ENST00000392546.6
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family member 1
chr2_-_32265732 2.04 ENST00000360906.9
ENST00000342905.10
NLRC4
NLR family CARD domain containing 4
chr5_+_147878703 2.00 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr13_-_99258366 1.98 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr7_-_26995237 1.98 ENST00000432747.1
SKAP2
src kinase associated phosphoprotein 2
chr20_-_64079906 1.96 ENST00000332298.9
RGS19
regulator of G protein signaling 19
chr14_+_22207502 1.95 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chrX_-_19799751 1.89 ENST00000379698.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr6_-_111793871 1.88 ENST00000368667.6
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr3_-_121660892 1.84 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_+_137998735 1.79 ENST00000343735.8
CLDN18
claudin 18
chr10_+_26438317 1.73 ENST00000376236.9
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
chr3_+_113532508 1.68 ENST00000264852.9
SIDT1
SID1 transmembrane family member 1
chrX_+_135520616 1.67 ENST00000370752.4
ENST00000639893.2
INTS6L
integrator complex subunit 6 like
chr19_-_54281145 1.66 ENST00000434421.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin like receptor B2
chr7_+_114922854 1.64 ENST00000423503.1
ENST00000427207.5
MDFIC
MyoD family inhibitor domain containing
chr1_+_91501097 1.63 ENST00000428239.5
ENST00000426137.1
CDC7
cell division cycle 7
chr6_+_31586269 1.60 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr12_+_9971402 1.56 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
CLEC12A
C-type lectin domain family 12 member A
chr22_+_22747383 1.56 ENST00000390311.3
IGLV3-16
immunoglobulin lambda variable 3-16
chr19_-_38878247 1.55 ENST00000591812.2
RINL
Ras and Rab interactor like
chr12_-_39619782 1.55 ENST00000308666.4
ABCD2
ATP binding cassette subfamily D member 2
chr4_+_73853290 1.55 ENST00000226524.4
PF4V1
platelet factor 4 variant 1
chr4_-_158173004 1.54 ENST00000585682.6
GASK1B
golgi associated kinase 1B
chrX_+_65667645 1.52 ENST00000360270.7
MSN
moesin
chr17_-_49209367 1.51 ENST00000300406.6
ENST00000511277.5
ENST00000511673.1
GNGT2
G protein subunit gamma transducin 2
chr14_+_88005128 1.49 ENST00000267549.5
GPR65
G protein-coupled receptor 65
chr13_+_49628489 1.48 ENST00000282026.2
ARL11
ADP ribosylation factor like GTPase 11
chr11_+_60056587 1.48 ENST00000395032.6
ENST00000358152.6
MS4A3
membrane spanning 4-domains A3
chr19_-_54281082 1.46 ENST00000314446.10
LILRB2
leukocyte immunoglobulin like receptor B2
chr1_+_91500827 1.45 ENST00000234626.11
CDC7
cell division cycle 7
chrX_+_108045050 1.45 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr7_-_22193728 1.42 ENST00000620335.4
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr2_-_227717981 1.42 ENST00000409456.2
ENST00000409287.5
ENST00000644224.2
ENST00000456524.6
SLC19A3
solute carrier family 19 member 3
chr12_-_10849464 1.40 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
PRR4
proline rich 4
chr15_+_76995118 1.40 ENST00000558012.6
ENST00000379595.7
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_-_39280432 1.38 ENST00000542107.5
ENST00000435290.1
CX3CR1
C-X3-C motif chemokine receptor 1
chr3_-_39281261 1.36 ENST00000541347.5
ENST00000412814.1
CX3CR1
C-X3-C motif chemokine receptor 1
chr10_-_95656643 1.32 ENST00000371221.3
ENST00000371224.7
ALDH18A1
aldehyde dehydrogenase 18 family member A1
chr8_-_38382146 1.32 ENST00000534155.1
ENST00000433384.6
ENST00000317025.13
ENST00000316985.7
NSD3
nuclear receptor binding SET domain protein 3
chr1_+_244051275 1.32 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr16_+_11965234 1.30 ENST00000562385.1
TNFRSF17
TNF receptor superfamily member 17
chr7_-_24918080 1.29 ENST00000441059.5
ENST00000415162.5
OSBPL3
oxysterol binding protein like 3
chr1_+_158930778 1.28 ENST00000458222.5
PYHIN1
pyrin and HIN domain family member 1
chr2_+_151357583 1.25 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr19_-_43667666 1.24 ENST00000593714.5
PLAUR
plasminogen activator, urokinase receptor
chr9_-_115118145 1.23 ENST00000350763.9
TNC
tenascin C
chr11_-_44950867 1.19 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr5_-_177554545 1.17 ENST00000514747.6
FAM193B
family with sequence similarity 193 member B
chr4_-_158173042 1.15 ENST00000592057.1
ENST00000393807.9
GASK1B
golgi associated kinase 1B
chr2_+_218245426 1.13 ENST00000456575.1
ARPC2
actin related protein 2/3 complex subunit 2
chr5_+_69189536 1.12 ENST00000515001.5
ENST00000283006.7
ENST00000502689.1
CENPH
centromere protein H
chr1_+_6034980 1.10 ENST00000378092.6
ENST00000472700.7
KCNAB2
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr2_+_10368645 1.10 ENST00000613496.4
HPCAL1
hippocalcin like 1
chr14_-_106875069 1.10 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr2_+_10368764 1.09 ENST00000620771.4
HPCAL1
hippocalcin like 1
chr6_-_28923932 1.07 ENST00000377199.4
ENST00000377194.7
TRIM27
tripartite motif containing 27
chr15_+_64911869 1.07 ENST00000319580.13
ENST00000496660.5
ANKDD1A
ankyrin repeat and death domain containing 1A
chr1_+_103750406 1.06 ENST00000370079.3
AMY1C
amylase alpha 1C
chr8_-_16192644 1.06 ENST00000262101.10
ENST00000381998.8
MSR1
macrophage scavenger receptor 1
chr1_+_159302321 1.05 ENST00000368114.1
FCER1A
Fc fragment of IgE receptor Ia
chrX_+_108044967 1.03 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr4_-_112285892 1.03 ENST00000361717.4
TIFA
TRAF interacting protein with forkhead associated domain
chr7_-_36985060 1.02 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr12_+_54854505 1.00 ENST00000308796.11
ENST00000619042.1
MUCL1
mucin like 1
chr12_-_14938508 0.99 ENST00000266397.7
ERP27
endoplasmic reticulum protein 27
chr1_+_100345018 0.97 ENST00000635056.2
ENST00000647005.1
CDC14A
cell division cycle 14A
chr6_-_2744126 0.97 ENST00000647417.1
MYLK4
myosin light chain kinase family member 4
chr4_+_8229170 0.96 ENST00000511002.6
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr19_+_19458458 0.95 ENST00000358713.7
GATAD2A
GATA zinc finger domain containing 2A
chr6_+_135181361 0.95 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB
MYB proto-oncogene, transcription factor
chr19_+_54906140 0.95 ENST00000291890.9
ENST00000598576.5
ENST00000594765.5
ENST00000350790.9
ENST00000338835.9
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr17_+_46713149 0.93 ENST00000576346.5
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr16_+_22505845 0.92 ENST00000356156.7
NPIPB5
nuclear pore complex interacting protein family member B5
chr12_+_9971512 0.92 ENST00000350667.4
CLEC12A
C-type lectin domain family 12 member A
chr11_-_89063631 0.91 ENST00000455756.6
GRM5
glutamate metabotropic receptor 5
chr10_+_26438404 0.89 ENST00000356785.4
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
chr1_-_111427731 0.87 ENST00000369732.4
OVGP1
oviductal glycoprotein 1
chr6_-_111793900 0.86 ENST00000462598.7
FYN
FYN proto-oncogene, Src family tyrosine kinase
chr12_+_40742342 0.86 ENST00000548005.5
ENST00000552248.5
CNTN1
contactin 1
chr1_+_50103903 0.84 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4
chr3_+_150603279 0.83 ENST00000615547.4
ENST00000477889.5
ENST00000471696.6
ENST00000485923.1
SELENOT
selenoprotein T
chr1_+_19640520 0.82 ENST00000428975.5
NBL1
NBL1, DAN family BMP antagonist
chr19_+_49487510 0.81 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr18_-_50287570 0.81 ENST00000586837.1
ENST00000412036.6
ENST00000589940.5
ENST00000587396.1
ENST00000591474.5
ENST00000285106.11
CXXC1
CXXC finger protein 1
chr17_+_41689862 0.80 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr14_-_68978240 0.80 ENST00000556571.1
ENST00000553659.1
ENST00000555616.5
ACTN1
actinin alpha 1
chr6_-_34426052 0.79 ENST00000344700.8
ENST00000644700.1
ENST00000648437.1
ENST00000644393.1
ENST00000639725.1
RPS10
RPS10-NUDT3
ribosomal protein S10
RPS10-NUDT3 readthrough
chr6_-_31680377 0.79 ENST00000383237.4
LY6G5C
lymphocyte antigen 6 family member G5C
chr1_+_147242654 0.78 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
CHD1L
chromodomain helicase DNA binding protein 1 like
chr17_-_181640 0.77 ENST00000613549.3
DOC2B
double C2 domain beta
chr8_-_23457618 0.76 ENST00000358689.9
ENST00000518718.1
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr11_-_101583985 0.75 ENST00000344327.8
TRPC6
transient receptor potential cation channel subfamily C member 6
chr3_+_63652663 0.75 ENST00000343837.8
ENST00000469440.5
SNTN
sentan, cilia apical structure protein
chr3_-_146528750 0.73 ENST00000483300.5
PLSCR1
phospholipid scramblase 1
chr12_-_108320635 0.72 ENST00000412676.5
ENST00000550573.5
CMKLR1
chemerin chemokine-like receptor 1
chr1_-_19484635 0.72 ENST00000433834.5
CAPZB
capping actin protein of muscle Z-line subunit beta
chr3_+_9797651 0.71 ENST00000453882.1
ARPC4-TTLL3
ARPC4-TTLL3 readthrough
chr19_+_57389839 0.71 ENST00000366197.9
ENST00000336128.12
ENST00000596282.5
ENST00000597400.5
ENST00000598895.5
ENST00000596617.5
ZNF548
ENSG00000269533.5
zinc finger protein 548
novel transcript
chr17_+_68035636 0.71 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
KPNA2
karyopherin subunit alpha 2
chr15_+_67067780 0.71 ENST00000679624.1
SMAD3
SMAD family member 3
chrX_+_106611930 0.71 ENST00000372544.6
ENST00000372548.9
RADX
RPA1 related single stranded DNA binding protein, X-linked
chr3_+_62318983 0.70 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
C3orf14
chromosome 3 open reading frame 14
chr9_+_5450503 0.70 ENST00000381573.8
ENST00000381577.4
CD274
CD274 molecule
chr15_+_51377247 0.70 ENST00000396399.6
GLDN
gliomedin
chr4_+_118034480 0.67 ENST00000296499.6
NDST3
N-deacetylase and N-sulfotransferase 3
chr14_-_52695652 0.67 ENST00000629528.2
ERO1A
endoplasmic reticulum oxidoreductase 1 alpha
chrX_-_155334580 0.66 ENST00000369449.7
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr3_-_108058361 0.65 ENST00000398258.7
CD47
CD47 molecule
chr15_+_51377410 0.64 ENST00000612989.1
GLDN
gliomedin
chr12_+_54000096 0.63 ENST00000303450.5
HOXC9
homeobox C9
chr6_-_34426020 0.62 ENST00000621356.3
ENST00000494077.6
ENST00000639877.1
RPS10
RPS10-NUDT3
ribosomal protein S10
RPS10-NUDT3 readthrough
chr13_+_38349900 0.62 ENST00000437952.1
UFM1
ubiquitin fold modifier 1
chr14_-_22823386 0.60 ENST00000554741.5
SLC7A7
solute carrier family 7 member 7
chr6_-_69699124 0.60 ENST00000651675.1
LMBRD1
LMBR1 domain containing 1
chr19_+_21142024 0.60 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
ZNF431
zinc finger protein 431
chr6_-_130890393 0.59 ENST00000456097.6
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr8_+_21966215 0.58 ENST00000433566.8
XPO7
exportin 7
chr15_+_76995374 0.58 ENST00000559161.5
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_+_110339323 0.57 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RBM15
RNA binding motif protein 15
chr1_+_153778178 0.57 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr18_-_50287816 0.56 ENST00000589548.6
ENST00000673786.1
CXXC1
CXXC finger protein 1
chr1_-_7940825 0.56 ENST00000377507.8
TNFRSF9
TNF receptor superfamily member 9
chr6_-_31958935 0.56 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
NELFE
negative elongation factor complex member E
chr9_-_19786928 0.56 ENST00000341998.6
ENST00000286344.3
SLC24A2
solute carrier family 24 member 2
chr17_+_47253817 0.55 ENST00000559488.7
ENST00000571680.1
ITGB3
integrin subunit beta 3
chr3_-_98522514 0.54 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr3_+_119579577 0.53 ENST00000478927.5
ADPRH
ADP-ribosylarginine hydrolase
chr9_+_18474100 0.53 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTSL1
ADAMTS like 1
chr6_-_31958852 0.53 ENST00000375425.9
ENST00000426722.5
NELFE
negative elongation factor complex member E
chr17_+_59685117 0.53 ENST00000475458.1
CLTC
clathrin heavy chain
chr12_-_102478539 0.52 ENST00000424202.6
IGF1
insulin like growth factor 1
chr3_-_101513175 0.52 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SENP7
SUMO specific peptidase 7
chr8_-_16192772 0.52 ENST00000350896.3
MSR1
macrophage scavenger receptor 1
chr14_+_22875136 0.52 ENST00000551466.1
LRP10
LDL receptor related protein 10
chr17_-_49848017 0.52 ENST00000326219.5
ENST00000334568.8
ENST00000352793.6
ENST00000398154.5
ENST00000436235.5
TAC4
tachykinin precursor 4
chr3_-_50350710 0.51 ENST00000232501.8
NPRL2
NPR2 like, GATOR1 complex subunit
chr3_+_119579433 0.51 ENST00000481816.5
ADPRH
ADP-ribosylarginine hydrolase
chr7_-_140479476 0.51 ENST00000443720.6
ENST00000255977.7
MKRN1
makorin ring finger protein 1
chr17_-_75878542 0.51 ENST00000254816.6
TRIM47
tripartite motif containing 47
chr7_+_65373839 0.51 ENST00000431504.1
ENST00000328747.12
ZNF92
zinc finger protein 92
chr8_-_23457677 0.50 ENST00000356206.10
ENST00000417069.6
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr18_-_23437869 0.50 ENST00000542162.5
ENST00000582336.5
TMEM241
transmembrane protein 241
chr1_-_152159227 0.50 ENST00000316073.3
RPTN
repetin
chr2_-_230960954 0.48 ENST00000392039.2
GPR55
G protein-coupled receptor 55
chr7_-_2815226 0.48 ENST00000447791.1
ENST00000407904.7
GNA12
G protein subunit alpha 12
chr18_-_5521373 0.47 ENST00000580989.5
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr10_+_5094405 0.47 ENST00000380554.5
AKR1C3
aldo-keto reductase family 1 member C3
chr1_+_86993009 0.47 ENST00000370548.3
ENSG00000267561.2
novel protein
chr16_-_30894264 0.46 ENST00000380317.8
BCL7C
BAF chromatin remodeling complex subunit BCL7C
chr2_+_157257687 0.46 ENST00000259056.5
GALNT5
polypeptide N-acetylgalactosaminyltransferase 5
chr3_-_33659441 0.46 ENST00000650653.1
ENST00000480013.6
CLASP2
cytoplasmic linker associated protein 2
chr20_+_64080129 0.46 ENST00000355631.8
OPRL1
opioid related nociceptin receptor 1
chr6_+_12716801 0.46 ENST00000674595.1
PHACTR1
phosphatase and actin regulator 1
chr17_-_49208882 0.45 ENST00000503070.5
GNGT2
G protein subunit gamma transducin 2
chr7_-_11832190 0.45 ENST00000423059.9
ENST00000617773.1
THSD7A
thrombospondin type 1 domain containing 7A
chrX_-_13734575 0.45 ENST00000519885.5
ENST00000458511.7
ENST00000380579.6
ENST00000683983.1
ENST00000683569.1
ENST00000359680.9
TRAPPC2
trafficking protein particle complex 2
chr4_+_77020532 0.44 ENST00000506731.5
SEPTIN11
septin 11
chr8_-_134510182 0.44 ENST00000521673.5
ZFAT
zinc finger and AT-hook domain containing
chr10_+_66926028 0.43 ENST00000361320.5
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr4_+_159267737 0.43 ENST00000264431.8
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr14_-_23365149 0.43 ENST00000216733.8
EFS
embryonal Fyn-associated substrate
chr2_+_201129483 0.42 ENST00000440180.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr7_+_111091006 0.42 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr15_-_40874216 0.42 ENST00000220507.5
RHOV
ras homolog family member V
chr4_+_145481194 0.42 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr2_-_162243375 0.42 ENST00000188790.9
ENST00000443424.5
FAP
fibroblast activation protein alpha
chr11_+_65833944 0.42 ENST00000308342.7
SNX32
sorting nexin 32
chr12_-_113221022 0.42 ENST00000546692.1
IQCD
IQ motif containing D
chr2_+_201129318 0.41 ENST00000417748.1
CFLAR
CASP8 and FADD like apoptosis regulator

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
1.1 5.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.9 2.7 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.8 3.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.8 3.0 GO:0042631 cellular response to water deprivation(GO:0042631)
0.7 2.1 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.7 2.7 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.7 2.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.5 2.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 2.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.4 3.1 GO:0002666 positive regulation of T cell tolerance induction(GO:0002666)
0.4 2.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.2 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.3 1.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 3.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 2.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 0.9 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.3 2.0 GO:0070269 pyroptosis(GO:0070269)
0.3 1.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.3 0.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.9 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 1.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.9 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 1.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.6 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.2 2.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 1.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 1.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.2 0.7 GO:0010260 organ senescence(GO:0010260)
0.2 2.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2 0.8 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 2.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.5 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 1.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.1 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 2.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.1 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.9 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.7 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.5 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.9 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0038016 insulin receptor internalization(GO:0038016)
0.1 2.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.8 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.9 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.4 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 4.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.7 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:2001179 regulation of interleukin-10 secretion(GO:2001179) positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 2.7 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 1.5 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.7 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.5 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 3.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.2 GO:0030728 ovulation(GO:0030728)
0.0 6.4 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 2.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 1.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 4.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 1.9 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.0 GO:0007602 phototransduction(GO:0007602)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.1 GO:0032804 viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 2.4 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.0 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306) DNA methylation or demethylation(GO:0044728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 2.8 GO:0036398 TCR signalosome(GO:0036398)
0.4 1.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 2.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.3 1.3 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.3 0.9 GO:0030312 external encapsulating structure(GO:0030312)
0.2 5.3 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.1 GO:1990031 pinceau fiber(GO:1990031)
0.1 3.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.1 GO:0032021 NELF complex(GO:0032021)
0.1 3.2 GO:0042588 zymogen granule(GO:0042588)
0.1 0.5 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.8 GO:0097452 GAIT complex(GO:0097452)
0.1 1.7 GO:0071438 invadopodium membrane(GO:0071438)
0.1 4.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 10.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 1.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 4.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.1 GO:0042629 mast cell granule(GO:0042629)
0.1 3.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 2.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 2.1 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 3.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 1.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 8.1 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0034709 methylosome(GO:0034709)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.7 2.7 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.5 8.5 GO:0042608 T cell receptor binding(GO:0042608)
0.5 2.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.5 1.4 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.4 3.1 GO:0023029 MHC class Ib protein binding(GO:0023029) inhibitory MHC class I receptor activity(GO:0032396)
0.3 1.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 0.9 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.3 2.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 2.3 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.7 GO:0001626 nociceptin receptor activity(GO:0001626)
0.2 3.7 GO:0046625 sphingolipid binding(GO:0046625)
0.2 1.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 0.5 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.2 2.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 1.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 3.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 4.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.8 GO:0016015 morphogen activity(GO:0016015)
0.1 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.7 GO:0008494 translation activator activity(GO:0008494)
0.1 1.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 2.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 10.6 GO:0003823 antigen binding(GO:0003823)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 4.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 5.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 3.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 3.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 5.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 3.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 3.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.0 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 3.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.5 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.8 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.2 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription