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avrg: Illumina Body Map 2 (GSE30611)

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Results for PKNOX1_TGIF2

Z-value: 1.33

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
ENSG00000160199.15 PKNOX1
ENSG00000118707.11 TGIF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg38_v1_chr20_+_36574535_365746720.431.5e-02Click!
PKNOX1hg38_v1_chr21_+_42974510_429746490.261.5e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_33447553 5.05 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr4_-_174522791 2.72 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr4_-_174522446 2.52 ENST00000296521.11
ENST00000296522.11
ENST00000422112.6
ENST00000504433.1
15-hydroxyprostaglandin dehydrogenase
chr3_+_111542178 2.43 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr4_-_174522315 2.33 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr21_-_32813679 2.17 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr1_+_207089195 2.16 ENST00000452902.6
complement component 4 binding protein beta
chr21_-_32813695 2.13 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr3_+_111542134 2.12 ENST00000438817.6
CD96 molecule
chr1_+_207089233 2.12 ENST00000243611.9
ENST00000367076.7
complement component 4 binding protein beta
chrX_+_136648138 1.95 ENST00000370629.7
CD40 ligand
chr6_+_26124161 1.89 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr1_+_207088825 1.87 ENST00000367078.8
complement component 4 binding protein beta
chr1_+_207089283 1.86 ENST00000391923.1
complement component 4 binding protein beta
chr14_-_94390667 1.82 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr14_-_94390614 1.79 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr14_-_94390650 1.77 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chrX_+_136648214 1.75 ENST00000370628.2
CD40 ligand
chr2_-_189582012 1.71 ENST00000427419.5
ENST00000455320.5
solute carrier family 40 member 1
chr19_-_48044037 1.65 ENST00000293255.3
calcium binding protein 5
chr2_+_233760265 1.65 ENST00000305208.10
ENST00000360418.4
UDP glucuronosyltransferase family 1 member A1
chr7_+_142740206 1.62 ENST00000422143.2
T cell receptor beta variable 29-1
chr3_+_52794768 1.42 ENST00000621946.4
ENST00000416872.6
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr1_+_23959109 1.37 ENST00000471915.5
proline rich nuclear receptor coactivator 2
chr6_+_31706866 1.33 ENST00000375832.5
ENST00000503322.1
lymphocyte antigen 6 family member G6F
LY6G6F-LY6G6D readthrough
chr3_-_112133218 1.30 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr9_-_112890868 1.26 ENST00000374228.5
solute carrier family 46 member 2
chr7_+_142554828 1.23 ENST00000611787.1
T cell receptor beta variable 11-3
chr16_+_2537997 1.20 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr11_+_6390439 1.20 ENST00000530395.1
ENST00000342245.9
ENST00000527275.5
sphingomyelin phosphodiesterase 1
chr18_+_56651661 1.18 ENST00000593058.1
WD repeat domain 7
chr16_-_30445865 1.17 ENST00000478753.5
selenophosphate synthetase 2
chr1_+_230067198 1.17 ENST00000366672.5
polypeptide N-acetylgalactosaminyltransferase 2
chr1_-_12616762 1.12 ENST00000464917.5
dehydrogenase/reductase 3
chr10_-_72088972 1.09 ENST00000317376.8
ENST00000412663.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr8_+_28317265 1.08 ENST00000301908.8
prepronociceptin
chr13_-_46142834 1.08 ENST00000674665.1
lymphocyte cytosolic protein 1
chr13_+_24270713 1.06 ENST00000409126.5
spermatogenesis associated 13
chr7_+_29194757 1.05 ENST00000222792.11
chimerin 2
chr3_-_27722316 1.04 ENST00000449599.4
eomesodermin
chr5_-_170297746 1.01 ENST00000046794.10
lymphocyte cytosolic protein 2
chr9_-_120877167 1.01 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr18_+_56651385 0.99 ENST00000615645.4
WD repeat domain 7
chr2_+_112564362 0.98 ENST00000458012.2
RNA polymerase I subunit B
chr16_+_27402167 0.97 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr16_+_2537979 0.96 ENST00000566659.1
3-phosphoinositide dependent protein kinase 1
chr14_+_103121457 0.94 ENST00000333007.8
TNF alpha induced protein 2
chr7_+_100373458 0.93 ENST00000453419.5
ENST00000198536.7
ENST00000394000.6
ENST00000350573.2
paired immunoglobin like type 2 receptor alpha
chr17_-_74361860 0.91 ENST00000375366.4
BTB domain containing 17
chr5_-_65723007 0.91 ENST00000506816.1
small glutamine rich tetratricopeptide repeat containing beta
chr22_+_25219633 0.91 ENST00000398215.3
crystallin beta B2
chr6_+_137867414 0.90 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr1_-_54406385 0.90 ENST00000610401.5
single stranded DNA binding protein 3
chr3_-_27722699 0.89 ENST00000461503.2
eomesodermin
chr9_-_120877026 0.87 ENST00000436309.5
PHD finger protein 19
chr8_+_28316979 0.87 ENST00000518479.5
prepronociceptin
chr2_+_85577540 0.86 ENST00000263864.10
ENST00000409760.1
vesicle associated membrane protein 8
chr8_-_17895403 0.85 ENST00000381840.5
ENST00000398054.5
fibrinogen like 1
chr18_+_56651335 0.85 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr22_-_37244237 0.84 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr12_-_121296669 0.83 ENST00000652382.1
calcium/calmodulin dependent protein kinase kinase 2
chr19_+_35902486 0.83 ENST00000246551.9
ENST00000437550.2
hematopoietic cell signal transducer
chr16_+_50742110 0.81 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr8_+_31639222 0.81 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr6_-_32173109 0.80 ENST00000395496.5
1-acylglycerol-3-phosphate O-acyltransferase 1
chr17_-_66229380 0.79 ENST00000205948.11
apolipoprotein H
chr1_-_203182805 0.78 ENST00000404436.2
chitinase 3 like 1
chr16_+_50742037 0.78 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr1_+_145719483 0.76 ENST00000369288.7
CD160 molecule
chr2_-_74553049 0.75 ENST00000409549.5
lysyl oxidase like 3
chr12_+_59596137 0.75 ENST00000549465.5
solute carrier family 16 member 7
chr17_+_8413124 0.74 ENST00000582812.5
nudE neurodevelopment protein 1 like 1
chr19_-_54100792 0.74 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
osteoclast associated Ig-like receptor
chr9_-_108934060 0.74 ENST00000675406.1
ENST00000676237.1
ENST00000675825.1
ENST00000675052.1
ENST00000674535.1
ENST00000674938.1
ENST00000374647.10
elongator acetyltransferase complex subunit 1
chr16_-_79600698 0.74 ENST00000393350.1
MAF bZIP transcription factor
chr14_-_21526312 0.71 ENST00000537235.2
spalt like transcription factor 2
chr2_+_218217131 0.71 ENST00000420104.5
ENST00000315717.10
ENST00000295685.14
actin related protein 2/3 complex subunit 2
chr8_+_96645221 0.71 ENST00000220763.10
carboxypeptidase Q
chr22_-_37244417 0.70 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr16_+_50742059 0.70 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr6_+_31919984 0.69 ENST00000413154.5
complement C2
chr15_+_68054308 0.69 ENST00000249636.11
protein inhibitor of activated STAT 1
chr14_-_94293024 0.68 ENST00000393096.5
serpin family A member 10
chr8_+_31639291 0.68 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr12_-_121296685 0.67 ENST00000412367.6
ENST00000404169.8
ENST00000402834.8
calcium/calmodulin dependent protein kinase kinase 2
chr2_+_234050679 0.66 ENST00000373368.5
ENST00000168148.8
secreted phosphoprotein 2
chr21_+_29130961 0.66 ENST00000399925.5
MAP3K7 C-terminal like
chr13_+_24270681 0.66 ENST00000343003.10
ENST00000399949.6
spermatogenesis associated 13
chr4_+_8182066 0.66 ENST00000508641.2
SH3 domain and tetratricopeptide repeats 1
chr18_+_3449413 0.64 ENST00000549253.5
TGFB induced factor homeobox 1
chr18_+_3449817 0.63 ENST00000407501.6
TGFB induced factor homeobox 1
chr18_+_3450036 0.63 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr2_-_224947030 0.63 ENST00000409592.7
dedicator of cytokinesis 10
chr12_+_62260374 0.63 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chr14_-_94293071 0.63 ENST00000554723.5
serpin family A member 10
chr1_-_244859297 0.62 ENST00000483966.3
heterogeneous nuclear ribonucleoprotein U
chr4_-_48114523 0.61 ENST00000506073.1
TXK tyrosine kinase
chr21_+_29130630 0.60 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr1_-_186680411 0.59 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr2_+_28778848 0.59 ENST00000418910.1
protein phosphatase 1 catalytic subunit beta
chr14_-_95157270 0.58 ENST00000674628.1
ENST00000529720.1
ENST00000393063.6
ENST00000532939.3
dicer 1, ribonuclease III
chr12_-_91004965 0.57 ENST00000261172.8
epiphycan
chr12_-_91005019 0.57 ENST00000551767.1
epiphycan
chr10_+_92848461 0.57 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr15_-_61229297 0.57 ENST00000335670.11
RAR related orphan receptor A
chr9_+_134880806 0.57 ENST00000291744.11
ENST00000350339.3
ficolin 2
chr6_+_137867241 0.57 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr12_+_121210065 0.56 ENST00000359949.11
ENST00000337233.9
ENST00000538701.5
purinergic receptor P2X 4
chr14_+_21797272 0.56 ENST00000390430.2
T cell receptor alpha variable 8-1
chr1_-_225427897 0.56 ENST00000421383.1
ENST00000272163.9
lamin B receptor
chr12_+_121210160 0.56 ENST00000542067.5
purinergic receptor P2X 4
chr10_-_46030585 0.54 ENST00000580070.5
ENST00000578454.5
ENST00000585056.5
ENST00000579039.2
ENST00000581486.6
nuclear receptor coactivator 4
chr7_+_1232865 0.53 ENST00000316333.9
UNC homeobox
chr11_-_72099212 0.53 ENST00000544594.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr4_+_56907876 0.52 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr3_+_184181985 0.51 ENST00000442686.1
adaptor related protein complex 2 subunit mu 1
chr6_+_32439866 0.51 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr3_-_190449782 0.51 ENST00000354905.3
transmembrane protein 207
chr13_-_38990824 0.51 ENST00000379631.9
stomatin like 3
chr18_-_69957176 0.51 ENST00000580335.1
CD226 molecule
chr2_+_234050732 0.50 ENST00000425558.1
secreted phosphoprotein 2
chr1_-_31919093 0.50 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2
chr1_+_145719468 0.50 ENST00000616463.1
CD160 molecule
chr16_-_79600727 0.49 ENST00000326043.5
MAF bZIP transcription factor
chr18_+_3449620 0.49 ENST00000405385.7
TGFB induced factor homeobox 1
chr7_+_17299234 0.49 ENST00000637807.1
novel protein
chr7_-_5528029 0.48 ENST00000464611.1
actin beta
chr20_+_56412249 0.48 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr9_-_120842898 0.48 ENST00000625444.1
ENST00000210313.8
ENST00000373904.5
proteasome 26S subunit, non-ATPase 5
chr12_-_14961256 0.48 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr18_+_3451585 0.48 ENST00000551541.5
TGFB induced factor homeobox 1
chr14_-_106117159 0.47 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr3_-_142448060 0.47 ENST00000264951.8
5'-3' exoribonuclease 1
chr19_+_7669043 0.46 ENST00000221515.6
resistin
chr16_+_85027761 0.46 ENST00000683363.1
KIAA0513
chr12_+_120071703 0.46 ENST00000548673.5
BICD family like cargo adaptor 1
chr16_+_85027735 0.46 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr14_+_22003106 0.45 ENST00000390446.3
T cell receptor alpha variable 18
chr2_+_241188509 0.43 ENST00000674324.1
ENST00000274979.12
anoctamin 7
chr16_+_66605518 0.43 ENST00000566121.1
CKLF like MARVEL transmembrane domain containing 3
chr3_-_49689053 0.43 ENST00000449682.2
macrophage stimulating 1
chr1_-_89126066 0.43 ENST00000370466.4
guanylate binding protein 2
chr3_-_33440510 0.42 ENST00000283628.9
ENST00000456378.1
upstream binding protein 1
chr3_-_183555696 0.42 ENST00000341319.8
kelch like family member 6
chr13_-_38990856 0.40 ENST00000423210.1
stomatin like 3
chr5_-_181239571 0.40 ENST00000509535.5
receptor for activated C kinase 1
chrX_-_154354889 0.40 ENST00000438732.2
filamin A
chr15_-_41513796 0.39 ENST00000561619.5
ENST00000263800.11
ENST00000355166.9
ENST00000453182.2
leukocyte receptor tyrosine kinase
chr7_-_42237059 0.38 ENST00000437480.1
GLI family zinc finger 3
chr11_-_68844252 0.38 ENST00000561996.1
carnitine palmitoyltransferase 1A
chr7_-_99735093 0.38 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr16_-_69384747 0.38 ENST00000566257.5
telomeric repeat binding factor 2
chr7_-_23347704 0.38 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr1_-_152159227 0.37 ENST00000316073.3
repetin
chr8_+_38387120 0.37 ENST00000526356.1
leucine zipper and EF-hand containing transmembrane protein 2
chr3_-_151249114 0.37 ENST00000424796.6
purinergic receptor P2Y14
chr11_-_67647577 0.37 ENST00000529256.1
aminoacylase 3
chr5_-_59586393 0.37 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chr1_-_154627576 0.36 ENST00000648311.1
adenosine deaminase RNA specific
chr3_-_142448028 0.36 ENST00000392981.7
5'-3' exoribonuclease 1
chr6_+_155013646 0.36 ENST00000538270.5
ENST00000535231.5
TIAM Rac1 associated GEF 2
chr18_+_3451647 0.35 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr19_+_11798514 0.35 ENST00000323169.10
ENST00000450087.1
zinc finger protein 491
chr17_+_39653080 0.35 ENST00000443521.1
StAR related lipid transfer domain containing 3
chr6_-_41705813 0.34 ENST00000419574.6
ENST00000445214.2
transcription factor EB
chr1_-_208244375 0.34 ENST00000367033.4
plexin A2
chr1_-_247008042 0.34 ENST00000339986.8
ENST00000487338.6
zinc finger protein 695
chr1_+_154993581 0.34 ENST00000392487.1
lens epithelial protein
chr12_+_121888751 0.34 ENST00000261817.6
ENST00000538613.5
ENST00000542602.1
ENST00000541212.6
proteasome 26S subunit, non-ATPase 9
chr17_-_41505695 0.34 ENST00000590425.1
keratin 13
chr18_+_59139864 0.34 ENST00000509791.7
ENST00000587834.6
ENST00000588875.2
SEC11 homolog C, signal peptidase complex subunit
chr9_+_135521432 0.34 ENST00000263598.6
ENST00000371781.4
lipocalin 1
chr3_-_71360753 0.33 ENST00000648783.1
forkhead box P1
chr11_+_64291992 0.33 ENST00000394525.6
potassium two pore domain channel subfamily K member 4
chr14_-_106791226 0.33 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr3_-_33440343 0.33 ENST00000283629.8
upstream binding protein 1
chr6_+_30328889 0.33 ENST00000396547.5
ENST00000623385.3
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr12_+_103587266 0.33 ENST00000388887.7
stabilin 2
chrX_-_15664798 0.32 ENST00000380342.4
collectrin, amino acid transport regulator
chr16_+_29778252 0.31 ENST00000400752.6
zymogen granule protein 16
chr18_-_70205655 0.31 ENST00000255674.11
ENST00000640769.2
rotatin
chr7_+_76510516 0.31 ENST00000257632.9
uroplakin 3B
chr16_-_30558263 0.31 ENST00000252797.6
zinc finger protein 764
chr14_-_21526391 0.31 ENST00000611430.4
spalt like transcription factor 2
chr3_-_45796467 0.31 ENST00000353278.8
ENST00000456124.6
solute carrier family 6 member 20
chr16_-_69384650 0.31 ENST00000569542.6
telomeric repeat binding factor 2
chr17_-_37609361 0.31 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr7_-_92142949 0.31 ENST00000435873.1
novel protein
chr19_+_2867327 0.31 ENST00000586426.5
ENST00000307635.3
zinc finger protein 556
chr1_+_76867469 0.31 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr22_+_20551000 0.30 ENST00000428629.5
mediator complex subunit 15
chr8_-_98825628 0.30 ENST00000617590.1
ENST00000518165.5
ENST00000419617.7
serine/threonine kinase 3
chr12_+_77324608 0.30 ENST00000550042.2
neuron navigator 3
chr2_-_74552616 0.30 ENST00000409249.5
lysyl oxidase like 3
chr7_+_95485898 0.30 ENST00000428113.5
ankyrin repeat and SOCS box containing 4
chr6_-_100881281 0.30 ENST00000369143.2
ENST00000369162.7
ENST00000324723.10
ENST00000522650.5
activating signal cointegrator 1 complex subunit 3
chr12_+_34022462 0.29 ENST00000538927.1
ENST00000266483.7
ALG10 alpha-1,2-glucosyltransferase
chr6_-_31684040 0.29 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr20_+_56412393 0.29 ENST00000679529.1
Cas scaffold protein family member 4
chr11_-_65134429 0.28 ENST00000526060.5
ENST00000307289.10
ENST00000528487.1
synoviolin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.9 8.0 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.8 5.1 GO:0070295 renal water absorption(GO:0070295)
0.6 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 2.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.6 1.7 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.5 7.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.4 1.6 GO:0018879 biphenyl metabolic process(GO:0018879)
0.4 1.5 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.3 0.9 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.3 1.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.3 0.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.3 0.8 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 1.5 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.2 1.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 2.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.7 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.2 0.5 GO:0097086 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.2 0.7 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.2 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.6 GO:0036404 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.1 3.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 1.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.5 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 2.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.0 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0060367 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1 0.3 GO:0071314 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) cellular response to cocaine(GO:0071314)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.2 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0032439 endosome localization(GO:0032439)
0.1 1.1 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.2 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 5.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0070650 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0097536 thymus epithelium morphogenesis(GO:0097536)
0.0 1.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.9 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.4 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.5 GO:0015816 glycine transport(GO:0015816)
0.0 1.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 1.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 1.0 GO:0045576 mast cell activation(GO:0045576)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 1.0 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.7 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.6 GO:0033167 ARC complex(GO:0033167)
0.1 2.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 8.6 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.7 GO:0000145 exocyst(GO:0000145)
0.0 5.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 3.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.5 GO:0044754 autolysosome(GO:0044754)
0.0 2.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 12.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 2.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.0 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.6 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.2 3.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.7 5.1 GO:0015254 glycerol channel activity(GO:0015254)
0.6 1.7 GO:0097689 iron channel activity(GO:0097689)
0.3 1.9 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.7 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 3.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.5 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 2.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.6 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.6 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.4 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.7 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 8.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.8 GO:0004568 chitinase activity(GO:0004568)
0.0 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 13.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 4.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 5.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 10.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 5.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors