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avrg: Illumina Body Map 2 (GSE30611)

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Results for RAD21_SMC3

Z-value: 1.54

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
ENSG00000164754.15 RAD21
ENSG00000108055.10 SMC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAD21hg38_v1_chr8_-_116874746_1168748280.392.7e-02Click!
SMC3hg38_v1_chr10_+_110567666_1105677650.291.0e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_22195753 3.40 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr7_+_142626642 3.38 ENST00000390394.3
T cell receptor beta variable 20-1
chr11_+_1876467 3.31 ENST00000432093.1
lymphocyte specific protein 1
chr22_+_22409755 3.23 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr14_+_21868822 3.14 ENST00000390436.2
T cell receptor alpha variable 13-1
chr14_+_21887848 3.08 ENST00000390437.2
T cell receptor alpha variable 12-2
chr22_+_22343185 2.96 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr14_+_21723693 2.89 ENST00000390425.2
T cell receptor alpha variable 3
chr7_+_142740206 2.73 ENST00000422143.2
T cell receptor beta variable 29-1
chr22_+_22380766 2.68 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr22_+_22369601 2.67 ENST00000390295.3
immunoglobulin lambda variable 7-46
chr19_-_55140922 2.53 ENST00000589745.5
troponin T1, slow skeletal type
chr14_+_21852457 2.52 ENST00000390435.1
T cell receptor alpha variable 8-3
chr22_+_22697789 2.47 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr17_+_47733228 2.41 ENST00000177694.2
T-box transcription factor 21
chr14_+_21978440 2.37 ENST00000390443.3
T cell receptor alpha variable 8-6
chr16_+_67645100 2.34 ENST00000334583.11
capping protein regulator and myosin 1 linker 2
chr14_+_21918161 2.34 ENST00000390439.2
T cell receptor alpha variable 13-2
chr16_+_67645166 2.33 ENST00000545661.5
capping protein regulator and myosin 1 linker 2
chr14_+_21894433 2.31 ENST00000390438.2
T cell receptor alpha variable 8-4
chr9_-_131739931 2.21 ENST00000438647.3
Rap guanine nucleotide exchange factor 1
chr14_+_21997531 2.19 ENST00000390445.2
T cell receptor alpha variable 17
chr19_-_55141889 2.19 ENST00000593194.5
troponin T1, slow skeletal type
chr14_+_22320128 2.17 ENST00000390468.1
T cell receptor alpha variable 41
chr19_+_18007182 2.17 ENST00000595712.6
arrestin domain containing 2
chr9_-_131740056 2.15 ENST00000372195.5
ENST00000683357.1
Rap guanine nucleotide exchange factor 1
chr6_-_41705813 1.98 ENST00000419574.6
ENST00000445214.2
transcription factor EB
chr7_-_38363476 1.98 ENST00000426402.2
T cell receptor gamma variable 2
chr14_+_21749163 1.98 ENST00000390427.3
T cell receptor alpha variable 5
chr15_-_64046322 1.93 ENST00000457488.5
ENST00000612884.4
death associated protein kinase 2
chr18_+_46173495 1.89 ENST00000587591.5
ENST00000588730.1
chromosome 18 open reading frame 25
chr19_+_49474208 1.89 ENST00000597551.6
ENST00000596435.5
ENST00000204637.6
ENST00000600429.5
fms related receptor tyrosine kinase 3 ligand
chr11_+_67266437 1.88 ENST00000308595.10
ENST00000526285.1
G protein-coupled receptor kinase 2
chrX_-_107777038 1.86 ENST00000480691.2
ENST00000506081.5
ENST00000514426.1
TSC22 domain family member 3
chr14_+_22040576 1.84 ENST00000390448.3
T cell receptor alpha variable 20
chr11_+_46347526 1.81 ENST00000456247.6
ENST00000421244.6
ENST00000318201.12
diacylglycerol kinase zeta
chr1_+_151156627 1.81 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr14_+_21841182 1.80 ENST00000390433.1
T cell receptor alpha variable 12-1
chr19_-_19643597 1.75 ENST00000587205.1
ENST00000203556.9
GEM interacting protein
chr17_+_74203582 1.73 ENST00000439590.6
ENST00000311111.11
ENST00000584577.5
ENST00000534490.5
ENST00000528433.2
ENST00000533498.1
ribosomal protein L38
chr22_+_22357739 1.73 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr19_-_19643547 1.69 ENST00000587238.5
GEM interacting protein
chr7_-_38359120 1.66 ENST00000390346.2
T cell receptor gamma variable 3
chr2_+_233354474 1.65 ENST00000264057.7
ENST00000427930.5
ENST00000442524.4
diacylglycerol kinase delta
chr22_+_22395005 1.61 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr11_-_17389323 1.61 ENST00000528731.1
potassium inwardly rectifying channel subfamily J member 11
chr11_+_46347425 1.60 ENST00000527911.5
diacylglycerol kinase zeta
chr19_-_41353904 1.60 ENST00000221930.6
transforming growth factor beta 1
chr10_-_29735787 1.54 ENST00000375400.7
supervillin
chr14_+_80955043 1.51 ENST00000541158.6
thyroid stimulating hormone receptor
chr6_-_41940537 1.50 ENST00000512426.5
cyclin D3
chr14_+_21797272 1.48 ENST00000390430.2
T cell receptor alpha variable 8-1
chr15_-_38564635 1.46 ENST00000450598.6
ENST00000559830.5
ENST00000558164.5
ENST00000539159.5
ENST00000310803.10
RAS guanyl releasing protein 1
chr14_+_22304051 1.35 ENST00000390466.1
T cell receptor alpha variable 39
chr17_-_8965674 1.35 ENST00000447110.6
ENST00000611902.4
ENST00000616147.4
ENST00000623421.3
phosphoinositide-3-kinase regulatory subunit 5
chr19_-_6481769 1.35 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENN domain containing 1C
chr7_-_38354517 1.34 ENST00000390345.2
T cell receptor gamma variable 4
chr12_-_120265719 1.33 ENST00000637617.2
ENST00000267257.11
ENST00000228307.11
ENST00000424649.6
paxillin
chr15_+_74782069 1.33 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr17_-_9959455 1.32 ENST00000580865.5
ENST00000583882.5
growth arrest specific 7
chr11_-_64744102 1.32 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr7_+_6589990 1.30 ENST00000344417.10
chromosome 7 open reading frame 26
chr10_+_102394488 1.28 ENST00000369966.8
nuclear factor kappa B subunit 2
chr14_+_80955366 1.28 ENST00000342443.10
thyroid stimulating hormone receptor
chr22_+_22431949 1.27 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_-_21952827 1.27 ENST00000397495.8
ENST00000263212.10
protein phosphatase, Mg2+/Mn2+ dependent 1F
chr17_+_44350437 1.26 ENST00000586443.1
granulin precursor
chr19_+_4791710 1.25 ENST00000269856.5
fem-1 homolog A
chr17_+_27456393 1.24 ENST00000644974.1
kinase suppressor of ras 1
chr14_+_21965451 1.22 ENST00000390442.3
T cell receptor alpha variable 12-3
chr16_-_69754913 1.20 ENST00000268802.10
NIN1 (RPN12) binding protein 1 homolog
chr19_-_48993300 1.19 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr19_-_6481749 1.19 ENST00000588421.1
DENN domain containing 1C
chr11_+_117232725 1.18 ENST00000531287.5
ENST00000531452.5
ring finger protein 214
chr5_+_138352674 1.18 ENST00000314358.10
lysine demethylase 3B
chr19_+_5690255 1.18 ENST00000582463.5
ENST00000347512.8
ENST00000579446.1
ENST00000394580.2
ribosomal protein L36
chr1_+_28518136 1.17 ENST00000373832.5
ENST00000373831.7
regulator of chromosome condensation 1
chr14_+_21768482 1.14 ENST00000390428.3
T cell receptor alpha variable 6
chr1_+_92832065 1.14 ENST00000315741.5
ribosomal protein L5
chr6_-_32953017 1.14 ENST00000395305.7
ENST00000374843.9
ENST00000395303.7
ENST00000429234.1
major histocompatibility complex, class II, DM alpha
novel protein
chr10_-_75109172 1.13 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr10_-_29735873 1.12 ENST00000674490.1
supervillin
chr11_-_17389083 1.11 ENST00000526912.1
potassium inwardly rectifying channel subfamily J member 11
chr19_-_48646155 1.10 ENST00000084798.9
carbonic anhydrase 11
chr8_-_27992663 1.10 ENST00000380385.6
ENST00000354914.8
scavenger receptor class A member 5
chr20_+_58852710 1.09 ENST00000676826.2
ENST00000371100.9
GNAS complex locus
chr9_+_36136752 1.09 ENST00000619700.1
GLI pathogenesis related 2
chr9_+_36136703 1.07 ENST00000377960.9
ENST00000377959.5
GLI pathogenesis related 2
chr22_-_21938557 1.06 ENST00000424647.1
ENST00000407142.5
protein phosphatase, Mg2+/Mn2+ dependent 1F
chr19_+_49474561 1.04 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr9_+_36136416 1.03 ENST00000396613.7
GLI pathogenesis related 2
chr19_-_18941184 1.02 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr7_+_6590070 1.02 ENST00000359073.9
chromosome 7 open reading frame 26
chr1_+_92832005 1.02 ENST00000645300.1
ribosomal protein L5
chr17_+_16415553 1.00 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr1_+_28518266 1.00 ENST00000411533.5
regulator of chromosome condensation 1
chr2_-_219160540 0.99 ENST00000457600.2
non-homologous end joining factor 1
chr14_+_55271344 0.98 ENST00000681400.1
ENST00000679934.1
ENST00000681904.1
ENST00000313833.5
F-box protein 34
chr16_-_11797208 0.97 ENST00000571198.5
ENST00000572781.5
ENST00000355758.9
zinc finger CCCH-type containing 7A
chr19_-_35135180 0.96 ENST00000392225.7
leucine rich repeat LGI family member 4
chr1_-_39901861 0.95 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chr6_+_106360668 0.93 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr1_-_39901996 0.91 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr9_+_126860625 0.91 ENST00000319119.4
zinc finger and BTB domain containing 34
chr1_+_151156659 0.91 ENST00000602841.5
sodium channel modifier 1
chr3_+_49803212 0.91 ENST00000333323.6
inka box actin regulator 1
chr1_+_92832028 0.90 ENST00000370321.8
ENST00000645119.1
ribosomal protein L5
chr17_-_8383164 0.90 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
ribosomal protein L26
chr19_+_1941118 0.90 ENST00000255641.13
casein kinase 1 gamma 2
chr8_-_143430727 0.89 ENST00000333480.3
MAF bZIP transcription factor A
chr19_+_1266653 0.88 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr19_-_18941117 0.88 ENST00000600077.5
homer scaffold protein 3
chr11_-_66336396 0.86 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr12_+_109900258 0.86 ENST00000405876.9
trichoplein keratin filament binding
chr12_-_120201099 0.86 ENST00000551150.5
ENST00000313104.9
ENST00000547191.5
ENST00000546989.5
ENST00000392514.9
ENST00000228306.8
ENST00000550856.5
ribosomal protein lateral stalk subunit P0
chr14_+_21825453 0.86 ENST00000390432.2
T cell receptor alpha variable 10
chr15_+_91853690 0.85 ENST00000318445.11
solute carrier organic anion transporter family member 3A1
chr11_+_3854527 0.82 ENST00000525403.5
ENST00000430222.1
stromal interaction molecule 1
novel transcript, sense overlapping STIM1
chr14_-_22823386 0.81 ENST00000554741.5
solute carrier family 7 member 7
chr17_-_63701140 0.81 ENST00000584645.1
LIM domain containing 2
chr1_-_202160577 0.80 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
protein tyrosine phosphatase non-receptor type 7
chr5_+_134524305 0.80 ENST00000431355.2
jade family PHD finger 2
chr11_+_7987314 0.79 ENST00000531572.2
ENST00000651655.1
eukaryotic translation initiation factor 3 subunit F
chr16_+_69311339 0.79 ENST00000254950.13
vacuolar protein sorting 4 homolog A
chr8_+_66429003 0.79 ENST00000320270.4
ribosome biogenesis regulator 1 homolog
chr12_-_101830926 0.78 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr2_-_165203870 0.77 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr19_+_55654115 0.77 ENST00000450554.6
U2 small nuclear RNA auxiliary factor 2
chr17_+_7688427 0.77 ENST00000396463.7
ENST00000534050.5
WD repeat containing antisense to TP53
chr12_-_56189548 0.76 ENST00000347471.8
ENST00000267064.8
ENST00000394023.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr13_-_52450590 0.76 ENST00000378060.9
vacuolar protein sorting 36 homolog
chr2_+_227472132 0.76 ENST00000409979.6
ENST00000310078.13
ArfGAP with FG repeats 1
chr11_-_18106019 0.75 ENST00000532452.5
ENST00000530180.1
ENST00000524803.6
ENST00000300013.8
ENST00000529318.5
serum amyloid A like 1
chr16_-_57536543 0.75 ENST00000258214.3
coiled-coil domain containing 102A
chr19_-_41353044 0.75 ENST00000600196.2
ENST00000677934.1
transforming growth factor beta 1
chr14_+_22207502 0.75 ENST00000390461.2
T cell receptor alpha variable 34
chr14_+_105491226 0.74 ENST00000451719.5
ENST00000392523.9
ENST00000392522.7
ENST00000354560.10
ENST00000334656.11
ENST00000450383.1
tubulin epsilon and delta complex 1
chr2_-_231530427 0.74 ENST00000305141.5
neuromedin U receptor 1
chr12_+_109900518 0.73 ENST00000312777.9
ENST00000536408.2
trichoplein keratin filament binding
chrX_-_72277235 0.73 ENST00000316084.10
ribosomal protein S4 X-linked
chr7_-_27180230 0.72 ENST00000396344.4
homeobox A10
chr10_-_75109085 0.72 ENST00000607131.5
dual specificity phosphatase 13
chr7_-_6348906 0.72 ENST00000313324.9
ENST00000530143.1
family with sequence similarity 220 member A
chr3_+_48465811 0.71 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr11_+_117232625 0.71 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chr16_+_4624811 0.70 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr6_-_41735557 0.69 ENST00000373033.6
transcription factor EB
chrX_-_46759055 0.69 ENST00000328306.4
ENST00000616978.5
solute carrier family 9 member A7
chr22_+_22720615 0.69 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr7_+_149147422 0.68 ENST00000475153.6
zinc finger protein 398
chr8_-_144787275 0.68 ENST00000343459.8
ENST00000429371.7
ENST00000534445.1
zinc finger protein 34
chr17_-_81869934 0.68 ENST00000580685.5
Rho GDP dissociation inhibitor alpha
chr17_+_2055094 0.67 ENST00000399849.4
ENST00000619757.5
HIC ZBTB transcriptional repressor 1
chr11_+_119206298 0.67 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chr16_+_57092570 0.67 ENST00000290776.13
ENST00000535318.6
copine 2
chr20_+_33731976 0.67 ENST00000375200.6
zinc finger protein 341
chr10_-_15719885 0.66 ENST00000378076.4
integrin subunit alpha 8
chr1_-_172444055 0.65 ENST00000344529.5
ENST00000367728.1
phosphatidylinositol glycan anchor biosynthesis class C
chr11_-_117232033 0.65 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr8_+_22589240 0.65 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr19_-_2051224 0.65 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr8_-_144409282 0.64 ENST00000620219.4
ENST00000616140.2
cleavage and polyadenylation specific factor 1
chr6_+_137867241 0.64 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr20_+_31514410 0.64 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr1_+_145845608 0.63 ENST00000334513.6
nudix hydrolase 17
chr1_-_226408045 0.63 ENST00000366794.10
ENST00000677203.1
poly(ADP-ribose) polymerase 1
chr18_+_46174014 0.63 ENST00000619301.4
ENST00000615052.5
chromosome 18 open reading frame 25
chr2_+_90021567 0.61 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr5_+_146447304 0.61 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
transcription elongation regulator 1
chr14_+_21846534 0.61 ENST00000390434.3
T cell receptor alpha variable 8-2
chr14_+_22226711 0.60 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr5_-_141619049 0.60 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr17_-_35119801 0.60 ENST00000592577.5
ENST00000590016.5
ENST00000345365.11
RAD51 paralog D
chr16_+_15643267 0.60 ENST00000396355.5
nudE neurodevelopment protein 1
chr4_+_74933108 0.60 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr4_-_15963165 0.59 ENST00000259989.7
fibroblast growth factor binding protein 2
chr1_-_6554501 0.59 ENST00000377705.6
nucleolar protein 9
chr1_+_211259932 0.59 ENST00000367005.8
REST corepressor 3
chr2_-_89160329 0.59 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr6_+_137867414 0.59 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr3_+_58306505 0.59 ENST00000461393.7
hydroxyacyl-thioester dehydratase type 2
chr6_-_18122677 0.59 ENST00000340650.6
NHL repeat containing E3 ubiquitin protein ligase 1
chr12_-_82358380 0.59 ENST00000256151.8
ENST00000552377.5
coiled-coil domain containing 59
chr19_-_10335773 0.58 ENST00000592439.1
intercellular adhesion molecule 3
chr3_-_184017863 0.58 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr10_-_75109106 0.58 ENST00000607487.5
dual specificity phosphatase 13
chr2_-_20651053 0.58 ENST00000631166.1
ENST00000402541.5
ENST00000446825.1
ENST00000406618.3
ENST00000304031.8
HCLS1 binding protein 3
chr14_-_93115812 0.57 ENST00000553452.5
inositol-tetrakisphosphate 1-kinase
chr17_-_42681840 0.57 ENST00000332438.4
C-C motif chemokine receptor 10
chr9_-_133149334 0.57 ENST00000393160.7
ral guanine nucleotide dissociation stimulator
chr1_+_10210562 0.57 ENST00000377093.9
ENST00000676179.1
kinesin family member 1B
chrX_+_11758159 0.57 ENST00000361672.6
ENST00000337339.7
ENST00000647869.1
ENST00000312196.10
ENST00000647857.1
ENST00000649130.1
MSL complex subunit 3
chr12_-_56189459 0.57 ENST00000550164.6
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr17_-_29180359 0.57 ENST00000531253.5
ENST00000628822.2
myosin XVIIIA
chr16_-_31202733 0.56 ENST00000350605.4
ENST00000247470.10
PYD and CARD domain containing
chr8_+_38901757 0.56 ENST00000616834.1
pleckstrin homology domain containing A2
chr8_+_42271289 0.56 ENST00000520810.6
ENST00000520835.7
inhibitor of nuclear factor kappa B kinase subunit beta
chr9_-_120477354 0.56 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr10_+_97572771 0.55 ENST00000370655.6
ENST00000455090.1
ankyrin repeat domain 2
chr8_+_38901218 0.55 ENST00000521746.5
ENST00000616927.4
pleckstrin homology domain containing A2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.7 2.8 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.7 3.3 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.6 2.4 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.6 2.9 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.5 4.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3 1.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 1.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 0.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.0 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 2.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.9 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 1.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.2 1.5 GO:0032252 secretory granule localization(GO:0032252)
0.2 1.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.7 GO:0048318 axial mesoderm development(GO:0048318)
0.2 0.6 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 0.8 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 0.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.2 0.6 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2 1.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 1.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 2.6 GO:0071316 cellular response to nicotine(GO:0071316)
0.2 4.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.2 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 2.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 0.9 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 2.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 5.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
0.1 0.6 GO:0036233 glycine import(GO:0036233)
0.1 0.9 GO:0031627 telomeric loop formation(GO:0031627)
0.1 1.6 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0032258 CVT pathway(GO:0032258)
0.1 1.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.7 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.3 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.4 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.7 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.8 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.6 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 1.3 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0019483 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.5 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.1 0.4 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 1.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.9 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.2 GO:0009946 proximal/distal axis specification(GO:0009946) semicircular canal formation(GO:0060876) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.6 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 16.0 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1 0.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.4 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.2 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 1.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 8.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.5 GO:0000050 urea cycle(GO:0000050) cellular response to lithium ion(GO:0071285)
0.0 2.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 1.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 3.3 GO:0006968 cellular defense response(GO:0006968)
0.0 2.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 2.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.9 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.3 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.4 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 2.0 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.3 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.9 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 1.0 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 2.9 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 1.0 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 1.0 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 2.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.0 GO:0060702 regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.0 GO:1904828 phenotypic switching(GO:0036166) regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of phenotypic switching(GO:1900239) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 2.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 1.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.2 2.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 4.7 GO:0005861 troponin complex(GO:0005861)
0.2 3.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.0 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.7 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 1.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 2.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.9 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.6 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.8 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 4.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 1.0 GO:0000791 euchromatin(GO:0000791)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 3.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 2.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.4 1.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.4 2.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 2.8 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.3 4.7 GO:0031014 troponin T binding(GO:0031014)
0.3 0.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 3.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 2.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 0.7 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.2 1.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 2.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.2 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.2 4.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.9 GO:0043426 MRF binding(GO:0043426)
0.2 5.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 0.7 GO:0097677 STAT family protein binding(GO:0097677)
0.2 2.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.5 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 0.6 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 3.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 27.1 GO:0003823 antigen binding(GO:0003823)
0.1 1.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 1.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.0 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 6.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.9 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.4 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0043531 ADP binding(GO:0043531)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 2.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 4.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 4.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 4.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 4.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 4.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 9.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 2.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC