ISMARA results: REL

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avrg: Illumina Body Map 2 (GSE30611)

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Results for REL

Z-value: 2.74

Motif logo

Transcription factors associated with REL

Gene Symbol	Gene ID	Gene Info
REL Ensembl NCBI GeneCards UniProt	ENSG00000162924.15	REL

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
REL	hg38_v1_chr2_+_60881553_60881619	0.30	1.0e-01	Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr2_-_89143133 Show fit	11.55	ENST00000492167.1	IGKV3-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-20
chr2_-_89010515 Show fit	10.22	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr2_-_89085787 Show fit	9.77	ENST00000390252.2	IGKV3-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-15
chr2_+_90038848 Show fit	7.93	ENST00000390270.2	IGKV3D-20 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-20
chr2_-_88947820 Show fit	7.71	ENST00000496168.1	IGKV1-5 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-5
chr2_+_90114838 Show fit	7.62	ENST00000417279.3	IGKV3D-15 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3D-15
chr22_+_22195753 Show fit	6.75	ENST00000390285.4	IGLV6-57 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 6-57
chr12_-_9760893 Show fit	6.60	ENST00000228434.7 ENST00000536709.1	CD69 Ensembl NCBI GeneCards UniProt Show fit	CD69 molecule
chr6_+_137867241 Show fit	6.20	ENST00000612899.5 ENST00000420009.5	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr6_+_137867414 Show fit	5.68	ENST00000237289.8 ENST00000433680.1	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr2_-_88979016 Show fit	5.59	ENST00000390247.2	IGKV3-7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 3-7 (non-functional)
chr22_-_19525369 Show fit	5.51	ENST00000403084.1 ENST00000413119.2	CLDN5 Ensembl NCBI GeneCards UniProt Show fit	claudin 5
chrX_-_154371210 Show fit	5.36	ENST00000369856.8 ENST00000422373.6 ENST00000360319.9	FLNA Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr8_-_23854796 Show fit	5.33	ENST00000290271.7	STC1 Ensembl NCBI GeneCards UniProt Show fit	stanniocalcin 1
chr11_+_102317450 Show fit	5.17	ENST00000615299.4 ENST00000527309.2 ENST00000526421.6 ENST00000263464.9	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr7_-_16804987 Show fit	4.73	ENST00000401412.5 ENST00000419304.7	AGR2 Ensembl NCBI GeneCards UniProt Show fit	anterior gradient 2, protein disulphide isomerase family member
chr6_-_31582415 Show fit	4.71	ENST00000429299.3 ENST00000446745.2	LTB Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr11_+_102317542 Show fit	4.58	ENST00000532808.5	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr11_+_102317492 Show fit	4.40	ENST00000673846.1	BIRC3 Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr2_+_227813834 Show fit	4.32	ENST00000358813.5 ENST00000409189.7	CCL20 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr10_+_17228515 Show fit	4.15	ENST00000478746.1	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr9_-_115118198 Show fit	4.10	ENST00000534839.1 ENST00000535648.5	TNC Ensembl NCBI GeneCards UniProt Show fit	tenascin C
chr14_+_103123452 Show fit	3.77	ENST00000558056.1 ENST00000560869.6	TNFAIP2 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 2
chr6_-_29559724 Show fit	3.73	ENST00000377050.5	UBD Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr9_-_115118145 Show fit	3.71	ENST00000350763.9	TNC Ensembl NCBI GeneCards UniProt Show fit	tenascin C
chr10_+_102395693 Show fit	3.62	ENST00000652277.1 ENST00000189444.11 ENST00000661543.1	NFKB2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr14_-_106658251 Show fit	3.51	ENST00000454421.2	IGHV3-64 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-64
chr17_-_78360066 Show fit	3.49	ENST00000587578.1 ENST00000330871.3	SOCS3 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 3
chr10_+_17228806 Show fit	3.47	ENST00000497849.1	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr19_-_46625037 Show fit	3.40	ENST00000596260.1 ENST00000594275.1 ENST00000597185.1 ENST00000598865.5 ENST00000291294.7	PTGIR Ensembl NCBI GeneCards UniProt Show fit	prostaglandin I2 receptor
chr4_+_73869385 Show fit	3.38	ENST00000395761.4	CXCL1 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 1
chr1_-_29181809 Show fit	3.31	ENST00000466448.4 ENST00000373795.7	SRSF4 Ensembl NCBI GeneCards UniProt Show fit	serine and arginine rich splicing factor 4
chr12_+_101877571 Show fit	3.28	ENST00000258534.13	DRAM1 Ensembl NCBI GeneCards UniProt Show fit	DNA damage regulated autophagy modulator 1
chr10_-_6062290 Show fit	3.26	ENST00000256876.10 ENST00000379954.5	IL2RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 2 receptor subunit alpha
chr12_+_101877658 Show fit	3.26	ENST00000544152.5	DRAM1 Ensembl NCBI GeneCards UniProt Show fit	DNA damage regulated autophagy modulator 1
chr10_+_88990531 Show fit	3.24	ENST00000355740.7	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr1_-_159924529 Show fit	3.20	ENST00000320307.8	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr11_-_128522285 Show fit	3.19	ENST00000319397.6 ENST00000535549.5	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr15_+_32717994 Show fit	3.15	ENST00000560677.5 ENST00000560830.1 ENST00000651154.1	GREM1 Ensembl NCBI GeneCards UniProt Show fit	gremlin 1, DAN family BMP antagonist
chr11_-_441964 Show fit	3.10	ENST00000332826.7	ANO9 Ensembl NCBI GeneCards UniProt Show fit	anoctamin 9
chr1_-_159925496 Show fit	3.09	ENST00000368097.9	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr18_+_23949847 Show fit	3.06	ENST00000588004.1	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr9_+_70043840 Show fit	3.06	ENST00000377182.5	MAMDC2 Ensembl NCBI GeneCards UniProt Show fit	MAM domain containing 2
chr17_+_36211055 Show fit	3.02	ENST00000617405.5 ENST00000617416.4 ENST00000613173.4 ENST00000620732.4 ENST00000620098.4 ENST00000620576.4 ENST00000620055.4 ENST00000610565.4 ENST00000620250.1	CCL4L2 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 4 like 2
chr4_-_73998669 Show fit	3.00	ENST00000296027.5	CXCL5 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 5
chr5_-_139462701 Show fit	2.99	ENST00000618155.3	ECSCR Ensembl NCBI GeneCards UniProt Show fit	endothelial cell surface expressed chemotaxis and apoptosis regulator
chr1_+_16440700 Show fit	2.98	ENST00000504551.6 ENST00000457722.6 ENST00000337132.10 ENST00000443980.6	NECAP2 Ensembl NCBI GeneCards UniProt Show fit	NECAP endocytosis associated 2
chr3_-_112641292 Show fit	2.96	ENST00000439685.6	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr20_+_45174894 Show fit	2.93	ENST00000243924.4	PI3 Ensembl NCBI GeneCards UniProt Show fit	peptidase inhibitor 3
chr10_+_88990621 Show fit	2.90	ENST00000352159.8	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr11_-_58578096 Show fit	2.88	ENST00000528954.5 ENST00000528489.1	LPXN Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr12_-_76878985 Show fit	2.85	ENST00000547435.1 ENST00000552330.5 ENST00000311083.10 ENST00000546966.5	CSRP2 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 2
chr19_+_14031746 Show fit	2.83	ENST00000263379.4	IL27RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 27 receptor subunit alpha
chr10_+_17229267 Show fit	2.80	ENST00000224237.9	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr5_+_119268689 Show fit	2.79	ENST00000274456.6	TNFAIP8 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 8
chr3_+_101827982 Show fit	2.78	ENST00000461724.5 ENST00000483180.5 ENST00000394054.6	NFKBIZ Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor zeta
chr4_-_74099187 Show fit	2.73	ENST00000508487.3	CXCL2 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 2
chr20_+_46118300 Show fit	2.73	ENST00000372285.8 ENST00000372276.7	CD40 Ensembl NCBI GeneCards UniProt Show fit	CD40 molecule
chr19_-_6591103 Show fit	2.73	ENST00000423145.7 ENST00000245903.4	CD70 Ensembl NCBI GeneCards UniProt Show fit	CD70 molecule
chr19_-_17847962 Show fit	2.72	ENST00000458235.7 ENST00000534444.1	JAK3 Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 3
chr4_-_74038681 Show fit	2.65	ENST00000296026.4	CXCL3 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 3
chr3_+_89107613 Show fit	2.63	ENST00000336596.7	EPHA3 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A3
chr1_+_202010575 Show fit	2.62	ENST00000367283.7 ENST00000367284.10	ELF3 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 3
chr4_+_168497044 Show fit	2.58	ENST00000505667.6	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr10_-_6062349 Show fit	2.58	ENST00000379959.8	IL2RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 2 receptor subunit alpha
chr18_+_23873000 Show fit	2.55	ENST00000269217.11 ENST00000587184.5	LAMA3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit alpha 3
chr10_+_30434021 Show fit	2.54	ENST00000542547.5	MAP3K8 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr11_-_128522189 Show fit	2.54	ENST00000526145.6	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr22_+_22162155 Show fit	2.54	ENST00000390284.2	IGLV4-60 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-60
chr20_+_46118277 Show fit	2.54	ENST00000620709.4	CD40 Ensembl NCBI GeneCards UniProt Show fit	CD40 molecule
chr10_+_88990736 Show fit	2.52	ENST00000357339.6 ENST00000652046.1 ENST00000355279.2	FAS Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr1_-_112707314 Show fit	2.49	ENST00000369642.7	RHOC Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member C
chr12_+_51238854 Show fit	2.48	ENST00000549732.6 ENST00000604900.5	DAZAP2 Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr4_-_76036060 Show fit	2.47	ENST00000306621.8	CXCL11 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 11
chr3_-_112641128 Show fit	2.44	ENST00000206423.8	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr11_+_114296347 Show fit	2.44	ENST00000299964.4	NNMT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr14_+_75522427 Show fit	2.43	ENST00000286639.8	BATF Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper ATF-like transcription factor
chr1_+_202010615 Show fit	2.40	ENST00000446188.1	ELF3 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 3
chr4_+_168497066 Show fit	2.38	ENST00000261509.10	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr10_+_102394488 Show fit	2.31	ENST00000369966.8	NFKB2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr9_-_133479075 Show fit	2.29	ENST00000414172.1 ENST00000371897.8 ENST00000371899.9	SLC2A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 6
chr8_-_47738153 Show fit	2.28	ENST00000408965.4	CEBPD Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein delta
chr16_+_27313879 Show fit	2.25	ENST00000562142.5 ENST00000561742.5 ENST00000543915.6 ENST00000395762.7 ENST00000563002.5	IL4R Ensembl NCBI GeneCards UniProt Show fit	interleukin 4 receptor
chr10_+_30434176 Show fit	2.24	ENST00000263056.6 ENST00000375322.2	MAP3K8 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr3_-_157160751 Show fit	2.23	ENST00000461804.5	CCNL1 Ensembl NCBI GeneCards UniProt Show fit	cyclin L1
chr14_-_68979436 Show fit	2.23	ENST00000193403.10	ACTN1 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr5_-_150412743 Show fit	2.20	ENST00000353334.11 ENST00000009530.12 ENST00000377795.7	CD74 Ensembl NCBI GeneCards UniProt Show fit	CD74 molecule
chr2_-_43226594 Show fit	2.17	ENST00000282388.4	ZFP36L2 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 2
chr1_-_32901330 Show fit	2.13	ENST00000329151.5 ENST00000373463.8	TMEM54 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 54
chr9_+_98943705 Show fit	2.11	ENST00000610452.1	COL15A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XV alpha 1 chain
chr5_+_177086867 Show fit	2.09	ENST00000503708.5 ENST00000393648.6 ENST00000514472.1 ENST00000502906.5 ENST00000292408.9 ENST00000510911.5	FGFR4 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 4
chr22_-_20437785 Show fit	2.09	ENST00000622235.5 ENST00000623402.1	SCARF2 Ensembl NCBI GeneCards UniProt Show fit	scavenger receptor class F member 2
chr1_-_89272775 Show fit	2.06	ENST00000443807.1	GBP5 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 5
chr1_+_109910840 Show fit	2.06	ENST00000329608.11 ENST00000488198.5	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr9_+_98943898 Show fit	1.95	ENST00000375001.8	COL15A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XV alpha 1 chain
chr18_+_3252267 Show fit	1.95	ENST00000536605.1 ENST00000580887.5	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr2_+_219229783 Show fit	1.94	ENST00000453432.5 ENST00000409849.5 ENST00000323348.10 ENST00000416565.1 ENST00000410034.7 ENST00000447157.5	ANKZF1 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
chr1_+_24745396 Show fit	1.92	ENST00000374379.9	CLIC4 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 4
chr17_-_75515509 Show fit	1.90	ENST00000321617.8	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr17_-_75515424 Show fit	1.88	ENST00000581870.1	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr8_-_48921419 Show fit	1.85	ENST00000020945.4	SNAI2 Ensembl NCBI GeneCards UniProt Show fit	snail family transcriptional repressor 2
chr2_+_161160420 Show fit	1.78	ENST00000392749.7 ENST00000405852.5	TANK Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr22_+_36922040 Show fit	1.77	ENST00000406230.5	CSF2RB Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 2 receptor subunit beta
chr9_-_130043154 Show fit	1.75	ENST00000355681.3 ENST00000446176.7 ENST00000443566.6 ENST00000420781.5	FNBP1 Ensembl NCBI GeneCards UniProt Show fit	formin binding protein 1
chrX_+_116436599 Show fit	1.74	ENST00000598581.3	SLC6A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 14
chr16_+_15643267 Show fit	1.74	ENST00000396355.5	NDE1 Ensembl NCBI GeneCards UniProt Show fit	nudE neurodevelopment protein 1
chr8_-_118951876 Show fit	1.72	ENST00000297350.9	TNFRSF11B Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 11b
chr1_-_204467216 Show fit	1.71	ENST00000367184.2	PIK3C2B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_-_128522264 Show fit	1.71	ENST00000531611.5	ETS1 Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr10_+_30434116 Show fit	1.70	ENST00000415139.5	MAP3K8 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr6_+_14117764 Show fit	1.70	ENST00000379153.4	CD83 Ensembl NCBI GeneCards UniProt Show fit	CD83 molecule
chr13_-_28495079 Show fit	1.70	ENST00000615840.4 ENST00000282397.9 ENST00000541932.5 ENST00000539099.1 ENST00000639477.1	FLT1 Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 1
chr10_+_87659839 Show fit	1.69	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_+_17228215 Show fit	1.68	ENST00000544301.7	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr11_+_64340191 Show fit	1.67	ENST00000356786.10	CCDC88B Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88B
chr3_+_141877529 Show fit	1.67	ENST00000495216.1	ATP1B3 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit beta 3
chr8_-_48921735 Show fit	1.66	ENST00000396822.6	SNAI2 Ensembl NCBI GeneCards UniProt Show fit	snail family transcriptional repressor 2
chr19_+_41219235 Show fit	1.66	ENST00000359092.7	AXL Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr3_+_89107649 Show fit	1.66	ENST00000452448.6 ENST00000494014.1	EPHA3 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A3
chr12_-_48924919 Show fit	1.65	ENST00000444214.6	FKBP11 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 11
chr2_+_201183120 Show fit	1.64	ENST00000272879.9 ENST00000286186.11 ENST00000374650.7 ENST00000346817.9 ENST00000313728.11 ENST00000448480.1	CASP10 Ensembl NCBI GeneCards UniProt Show fit	caspase 10
chr17_+_36210924 Show fit	1.62	ENST00000615418.4	CCL4L2 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 4 like 2
chr14_-_68979314 Show fit	1.61	ENST00000684713.1 ENST00000683198.1 ENST00000684598.1 ENST00000682331.1 ENST00000682291.1 ENST00000683342.1	ACTN1 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr1_+_109910892 Show fit	1.60	ENST00000369802.7 ENST00000420111.6	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr13_+_53028806 Show fit	1.59	ENST00000219022.3	OLFM4 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 4
chr2_+_218880844 Show fit	1.57	ENST00000258411.8	WNT10A Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 10A
chr19_+_41219177 Show fit	1.56	ENST00000301178.9	AXL Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr6_+_144150492 Show fit	1.53	ENST00000367568.5	STX11 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 11
chr2_+_108377947 Show fit	1.52	ENST00000272452.7	SULT1C4 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1C member 4
chr5_+_119268744 Show fit	1.51	ENST00000388882.5	TNFAIP8 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 8
chr21_+_33403391 Show fit	1.49	ENST00000290219.11 ENST00000381995.5	IFNGR2 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr1_-_204411804 Show fit	1.48	ENST00000367188.5	PPP1R15B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 15B
chr9_+_214843 Show fit	1.46	ENST00000432829.7	DOCK8 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 8
chr15_-_39920248 Show fit	1.46	ENST00000561100.2	GPR176 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 176
chr1_+_200894892 Show fit	1.46	ENST00000413687.3	INAVA Ensembl NCBI GeneCards UniProt Show fit	innate immunity activator
chr11_-_105023136 Show fit	1.43	ENST00000526056.5 ENST00000531367.5 ENST00000456094.1 ENST00000444749.6 ENST00000393141.6 ENST00000418434.5 ENST00000260315.8	CASP5 Ensembl NCBI GeneCards UniProt Show fit	caspase 5
chr11_+_827913 Show fit	1.42	ENST00000525077.2	CRACR2B Ensembl NCBI GeneCards UniProt Show fit	calcium release activated channel regulator 2B
chr8_+_69492793 Show fit	1.41	ENST00000616868.1 ENST00000419716.7 ENST00000402687.9	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr4_+_73836667 Show fit	1.41	ENST00000226317.10	CXCL6 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 6
chr17_+_17042505 Show fit	1.41	ENST00000577514.5	MPRIP Ensembl NCBI GeneCards UniProt Show fit	myosin phosphatase Rho interacting protein
chr19_+_40717091 Show fit	1.40	ENST00000263370.3	ITPKC Ensembl NCBI GeneCards UniProt Show fit	inositol-trisphosphate 3-kinase C
chr12_+_51238724 Show fit	1.37	ENST00000449723.7 ENST00000549555.5 ENST00000439799.6 ENST00000412716.8 ENST00000425012.6	DAZAP2 Ensembl NCBI GeneCards UniProt Show fit	DAZ associated protein 2
chr17_-_4949037 Show fit	1.36	ENST00000572383.1	PFN1 Ensembl NCBI GeneCards UniProt Show fit	profilin 1
chr19_-_47231191 Show fit	1.35	ENST00000439096.3	BBC3 Ensembl NCBI GeneCards UniProt Show fit	BCL2 binding component 3
chr2_-_98663464 Show fit	1.35	ENST00000414521.6	MGAT4A Ensembl NCBI GeneCards UniProt Show fit	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr16_+_27313662 Show fit	1.32	ENST00000566117.5	IL4R Ensembl NCBI GeneCards UniProt Show fit	interleukin 4 receptor
chr21_+_33403466 Show fit	1.32	ENST00000405436.5	IFNGR2 Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr19_+_40750859 Show fit	1.29	ENST00000601253.5 ENST00000597353.5 ENST00000599362.5	SNRPA Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr21_+_33266350 Show fit	1.28	ENST00000290200.7	IL10RB Ensembl NCBI GeneCards UniProt Show fit	interleukin 10 receptor subunit beta
chr1_+_109910581 Show fit	1.27	ENST00000357302.8	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr14_-_68796230 Show fit	1.27	ENST00000557086.1	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr2_+_201122477 Show fit	1.26	ENST00000425030.1	CFLAR Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD like apoptosis regulator
chr17_-_8383164 Show fit	1.25	ENST00000584164.6 ENST00000582556.5 ENST00000648839.1 ENST00000578812.5 ENST00000583011.6	RPL26 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L26
chr6_+_137867214 Show fit	1.25	ENST00000421450.1	TNFAIP3 Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr2_-_74465162 Show fit	1.20	ENST00000649854.1 ENST00000650523.1 ENST00000649601.1 ENST00000448666.7 ENST00000409065.5 ENST00000414701.1 ENST00000452063.7 ENST00000649075.1 ENST00000648810.1 ENST00000462443.2	MOGS Ensembl NCBI GeneCards UniProt Show fit	mannosyl-oligosaccharide glucosidase
chr5_+_50667405 Show fit	1.19	ENST00000505554.5	PARP8 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr9_-_133129395 Show fit	1.18	ENST00000393157.8	RALGDS Ensembl NCBI GeneCards UniProt Show fit	ral guanine nucleotide dissociation stimulator
chr22_-_27919199 Show fit	1.18	ENST00000634017.1 ENST00000436663.1 ENST00000320996.14 ENST00000335272.10 ENST00000455418.7	PITPNB Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol transfer protein beta
chr1_-_145957969 Show fit	1.18	ENST00000604000.4	LIX1L Ensembl NCBI GeneCards UniProt Show fit	limb and CNS expressed 1 like
chr17_-_63842918 Show fit	1.17	ENST00000577990.1	SMARCD2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr14_-_25010604 Show fit	1.17	ENST00000550887.5	STXBP6 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr12_-_57110284 Show fit	1.14	ENST00000543873.6 ENST00000554663.5 ENST00000557635.5	STAT6 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr17_-_63842663 Show fit	1.13	ENST00000613943.4 ENST00000448276.7	SMARCD2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr14_+_76761453 Show fit	1.12	ENST00000167106.9	VASH1 Ensembl NCBI GeneCards UniProt Show fit	vasohibin 1
chr11_+_66638678 Show fit	1.10	ENST00000578778.5 ENST00000483858.5 ENST00000398692.8 ENST00000310092.12 ENST00000510173.6 ENST00000506523.6 ENST00000530235.1 ENST00000532968.1	RBM4 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 4
chr11_+_66638661 Show fit	1.08	ENST00000396053.9 ENST00000408993.6	RBM4 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 4
chr14_+_75522531 Show fit	1.08	ENST00000555504.1	BATF Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper ATF-like transcription factor
chr13_-_37869723 Show fit	1.08	ENST00000426868.6 ENST00000379705.8 ENST00000338947.9 ENST00000355779.6 ENST00000358477.6 ENST00000379673.2	TRPC4 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 4
chr19_+_55654994 Show fit	1.07	ENST00000308924.9	U2AF2 Ensembl NCBI GeneCards UniProt Show fit	U2 small nuclear RNA auxiliary factor 2
chr6_+_135181268 Show fit	1.07	ENST00000341911.10 ENST00000442647.7 ENST00000618728.4 ENST00000316528.12 ENST00000616088.4	MYB Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr6_-_31806937 Show fit	1.07	ENST00000375661.6	LSM2 Ensembl NCBI GeneCards UniProt Show fit	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr17_+_40318237 Show fit	1.05	ENST00000394089.6 ENST00000425707.7	RARA Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor alpha
chr12_+_6946468 Show fit	1.04	ENST00000543115.5 ENST00000399448.5	PTPN6 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr1_+_47023659 Show fit	1.03	ENST00000371901.4	CYP4X1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 4 subfamily X member 1
chr1_-_155990062 Show fit	1.03	ENST00000462460.6	ARHGEF2 Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr19_+_35449584 Show fit	1.02	ENST00000246549.2	FFAR2 Ensembl NCBI GeneCards UniProt Show fit	free fatty acid receptor 2
chr4_-_184474037 Show fit	0.97	ENST00000510814.5 ENST00000507523.5 ENST00000506230.5	IRF2 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2
chr15_-_60397964 Show fit	0.97	ENST00000558998.5 ENST00000560165.5 ENST00000557986.5 ENST00000559467.5 ENST00000677968.1 ENST00000678450.1 ENST00000332680.8 ENST00000396024.7 ENST00000557906.6 ENST00000558558.6 ENST00000559113.6 ENST00000559780.6 ENST00000559956.6 ENST00000560468.6 ENST00000678870.1 ENST00000678061.1 ENST00000451270.7 ENST00000421017.6 ENST00000560466.5 ENST00000558132.5 ENST00000559370.5 ENST00000559725.5 ENST00000558985.6 ENST00000679109.1	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr10_-_13099652 Show fit	0.96	ENST00000378839.1	CCDC3 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 3
chr11_+_46277648 Show fit	0.96	ENST00000621158.5	CREB3L1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3 like 1
chr14_+_37197921 Show fit	0.95	ENST00000684589.1 ENST00000327441.11	MIPOL1 Ensembl NCBI GeneCards UniProt Show fit	mirror-image polydactyly 1
chr14_-_73458519 Show fit	0.95	ENST00000356296.8 ENST00000557597.5 ENST00000554394.5 ENST00000555238.6 ENST00000555987.5 ENST00000555394.5 ENST00000554546.5	NUMB Ensembl NCBI GeneCards UniProt Show fit	NUMB endocytic adaptor protein
chr12_-_58920465 Show fit	0.94	ENST00000320743.8	LRIG3 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and immunoglobulin like domains 3
chr4_-_184474518 Show fit	0.93	ENST00000393593.8	IRF2 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2
chr6_+_32154131 Show fit	0.92	ENST00000375143.6 ENST00000324816.11 ENST00000424499.1	PPT2 Ensembl NCBI GeneCards UniProt Show fit	palmitoyl-protein thioesterase 2
chr12_-_49110871 Show fit	0.92	ENST00000551782.5	LMBR1L Ensembl NCBI GeneCards UniProt Show fit	limb development membrane protein 1 like
chr11_-_66546228 Show fit	0.92	ENST00000526986.5	ZDHHC24 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type containing 24
chr1_-_155991198 Show fit	0.92	ENST00000673475.1	ARHGEF2 Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr12_+_11649666 Show fit	0.90	ENST00000396373.9	ETV6 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 6
chr6_+_32854179 Show fit	0.90	ENST00000374859.3	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr14_-_35404650 Show fit	0.90	ENST00000553342.1 ENST00000557140.5 ENST00000216797.10	NFKBIA Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor alpha
chr17_+_42288464 Show fit	0.88	ENST00000590726.7 ENST00000678903.1 ENST00000590949.6 ENST00000676585.1 ENST00000588868.5	STAT5A Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr1_+_44808482 Show fit	0.87	ENST00000450269.5 ENST00000409335.6	BTBD19 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 19
chr1_-_209651291 Show fit	0.87	ENST00000391911.5 ENST00000415782.1	LAMB3 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr15_+_41838839 Show fit	0.86	ENST00000458483.4	PLA2G4B Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IVB
chr2_+_201182873 Show fit	0.86	ENST00000360132.7	CASP10 Ensembl NCBI GeneCards UniProt Show fit	caspase 10
chr10_+_100997040 Show fit	0.86	ENST00000370223.7	LZTS2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper tumor suppressor 2
chr6_-_130970428 Show fit	0.83	ENST00000529208.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr2_-_96505345 Show fit	0.81	ENST00000310865.7 ENST00000451794.6	NEURL3 Ensembl NCBI GeneCards UniProt Show fit	neuralized E3 ubiquitin protein ligase 3
chr16_+_67537439 Show fit	0.81	ENST00000428437.6 ENST00000569253.5	RIPOR1 Ensembl NCBI GeneCards UniProt Show fit	RHO family interacting cell polarization regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	13.1	GO:0034148	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
2.6	7.8	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
1.6	3.1	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
1.5	5.9	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
1.3	6.3	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
1.2	3.5	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.2	5.8	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
1.1	5.6	GO:1904141	mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.1	4.3	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.1	4.3	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
1.1	5.4	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.0	8.7	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.9	4.7	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.9	3.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.8	14.2	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.8	3.1	GO:2001226	negative regulation of anion channel activity(GO:0010360) negative regulation of chloride transport(GO:2001226)
0.8	5.3	GO:0036018	cellular response to erythropoietin(GO:0036018)
0.7	2.2	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.7	7.4	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.7	12.1	GO:0070307	lens fiber cell development(GO:0070307)
0.6	1.7	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.6	1.7	GO:0036323	vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.6	1.7	GO:0000103	sulfate assimilation(GO:0000103)
0.6	1.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.6	7.3	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.5	2.5	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.5	1.5	GO:0061485	memory T cell proliferation(GO:0061485)
0.5	4.7	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.5	3.2	GO:2000669	positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.4	0.9	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4	3.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4	5.5	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4	2.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4	5.9	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.4	3.7	GO:0070842	aggresome assembly(GO:0070842)
0.4	1.1	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	1.8	GO:0038156	interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.3	1.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3	10.7	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.3	12.1	GO:0003094	glomerular filtration(GO:0003094)
0.3	2.1	GO:1903412	response to bile acid(GO:1903412)
0.3	4.9	GO:0051601	exocyst localization(GO:0051601)
0.3	5.0	GO:0060056	mammary gland involution(GO:0060056)
0.3	1.6	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3	2.1	GO:0032621	interleukin-18 production(GO:0032621)
0.3	1.3	GO:0097403	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2	2.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.2	1.9	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.2	1.0	GO:0052417	multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2	1.7	GO:1903288	positive regulation of potassium ion import(GO:1903288)
0.2	1.4	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.2	0.9	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.2	0.9	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	2.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.2	4.0	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.2	0.4	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2	2.2	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2	45.0	GO:0002377	immunoglobulin production(GO:0002377)
0.2	1.3	GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2	1.0	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.2	1.7	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.2	2.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2	0.7	GO:0010046	response to mycotoxin(GO:0010046)
0.2	1.6	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.2	0.5	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	1.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.2	6.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	3.0	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2	1.5	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.2	4.7	GO:0003334	keratinocyte development(GO:0003334)
0.2	1.4	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.4	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.1	1.5	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.1	0.5	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.5	GO:0097503	sialylation(GO:0097503)
0.1	0.7	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.1	19.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.9	GO:0007296	vitellogenesis(GO:0007296)
0.1	4.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1	3.8	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.5	GO:0090156	cellular sphingolipid homeostasis(GO:0090156)
0.1	2.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	1.3	GO:1903943	negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.4	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.1	1.6	GO:0048733	sebaceous gland development(GO:0048733)
0.1	2.9	GO:0007620	copulation(GO:0007620)
0.1	1.7	GO:0042832	defense response to protozoan(GO:0042832)
0.1	7.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	1.1	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.1	1.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	3.3	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1	0.6	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.1	1.7	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.1	1.9	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	1.4	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.4	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.4	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.1	0.5	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	0.2	GO:1904397	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1	0.2	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	1.5	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	2.3	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.2	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1	0.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.1	2.3	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	1.3	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	1.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	1.0	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.9	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.3	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	4.3	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	1.0	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0	0.8	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.8	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.6	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.8	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	4.3	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	2.0	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.6	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	4.9	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	5.6	GO:0002576	platelet degranulation(GO:0002576)
0.0	2.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.6	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	1.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.4	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	2.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	1.3	GO:0048512	circadian behavior(GO:0048512)
0.0	1.2	GO:0097352	autophagosome maturation(GO:0097352)
0.0	1.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.7	GO:0010884	positive regulation of lipid storage(GO:0010884)
0.0	0.3	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.7	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.3	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	1.7	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	1.9	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.2	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	1.2	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.0	0.5	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.3	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.5	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	1.4	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	1.2	GO:0015914	phospholipid transport(GO:0015914)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	11.5	GO:0071756	IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.5	5.9	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.8	5.4	GO:0031523	Myb complex(GO:0031523)
0.7	5.6	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.7	5.3	GO:0043196	varicosity(GO:0043196)
0.6	6.5	GO:0005610	laminin-5 complex(GO:0005610)
0.6	1.8	GO:0030526	granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.5	12.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.4	1.3	GO:0032002	interleukin-28 receptor complex(GO:0032002)
0.4	13.2	GO:0005614	interstitial matrix(GO:0005614)
0.4	0.7	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.2	4.1	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.2	1.4	GO:0097169	IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.2	1.0	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.2	2.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	0.5	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.2	1.1	GO:0089701	U2AF(GO:0089701)
0.2	1.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	4.9	GO:0000145	exocyst(GO:0000145)
0.1	3.8	GO:0005916	fascia adherens(GO:0005916)
0.1	5.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	9.7	GO:0002102	podosome(GO:0002102)
0.1	3.2	GO:0033643	host cell part(GO:0033643)
0.1	0.9	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.5	GO:0031905	early endosome lumen(GO:0031905)
0.1	1.6	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	1.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	22.7	GO:0072562	blood microparticle(GO:0072562)
0.1	0.5	GO:0035339	SPOTS complex(GO:0035339)
0.1	0.3	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	0.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0031251	PAN complex(GO:0031251)
0.1	1.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	1.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.3	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	5.8	GO:0035580	specific granule lumen(GO:0035580)
0.1	2.9	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	1.7	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	12.2	GO:0005882	intermediate filament(GO:0005882)
0.1	3.0	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	2.9	GO:0001533	cornified envelope(GO:0001533)
0.0	3.7	GO:0016235	aggresome(GO:0016235)
0.0	1.7	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.8	GO:0008091	spectrin(GO:0008091)
0.0	1.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	13.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	2.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.4	GO:0016600	flotillin complex(GO:0016600)
0.0	59.9	GO:0005615	extracellular space(GO:0005615)
0.0	0.4	GO:0030008	TRAPP complex(GO:0030008)
0.0	12.5	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	22.6	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	13.8	GO:0016607	nuclear speck(GO:0016607)
0.0	3.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	1.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0002080	acrosomal membrane(GO:0002080)
0.0	1.1	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	8.3	GO:0005925	focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	12.1	GO:1990254	keratin filament binding(GO:1990254)
1.5	5.8	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.2	3.6	GO:0004913	interleukin-4 receptor activity(GO:0004913)
1.1	8.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
1.1	4.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.0	15.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.9	7.8	GO:0045545	syndecan binding(GO:0045545)
0.7	5.6	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.6	5.4	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.6	4.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.6	1.7	GO:0036326	VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.4	2.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.4	7.7	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.4	2.5	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4	1.8	GO:0004912	interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.3	18.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3	3.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	75.1	GO:0003823	antigen binding(GO:0003823)
0.3	4.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.2	3.1	GO:0016015	morphogen activity(GO:0016015)
0.2	2.9	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	3.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.2	1.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	1.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	2.2	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.2	1.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	3.4	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.2	1.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	7.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	1.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	2.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	4.7	GO:0002162	dystroglycan binding(GO:0002162)
0.1	3.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.7	GO:0001727	lipid kinase activity(GO:0001727)
0.1	3.8	GO:0017166	vinculin binding(GO:0017166)
0.1	5.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	4.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	1.5	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	3.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	3.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	3.7	GO:0070628	proteasome binding(GO:0070628)
0.1	1.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.4	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	4.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	2.3	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	1.0	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	2.7	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	1.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	1.7	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0032428	sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1	0.7	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	1.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	1.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.8	GO:0042731	PH domain binding(GO:0042731)
0.1	0.9	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	1.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	1.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	0.7	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	1.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	4.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.4	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	1.4	GO:0035497	cAMP response element binding(GO:0035497)
0.0	1.6	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	3.5	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	2.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.7	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	2.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	1.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.7	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	1.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.9	GO:0015926	glucosidase activity(GO:0015926)
0.0	2.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	1.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	1.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	1.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	1.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.9	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	5.3	GO:0005179	hormone activity(GO:0005179)
0.0	0.7	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	2.1	GO:0050699	WW domain binding(GO:0050699)
0.0	0.9	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	1.2	GO:0005109	frizzled binding(GO:0005109)
0.0	4.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	1.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	2.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.5	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.8	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	1.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.9	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.6	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.6	GO:0070330	aromatase activity(GO:0070330)
0.0	10.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	9.4	GO:0045296	cadherin binding(GO:0045296)
0.0	3.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	2.5	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	6.1	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.4	GO:0001848	complement binding(GO:0001848)
0.0	2.9	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	25.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4	20.8	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	4.7	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.3	6.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.3	6.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	2.7	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	3.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	5.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	11.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	12.1	PID AURORA B PATHWAY	Aurora B signaling
0.1	5.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	8.9	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	8.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	4.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	1.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	4.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	6.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	6.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	2.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	1.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	4.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	2.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	2.6	PID REELIN PATHWAY	Reelin signaling pathway
0.0	3.1	PID BMP PATHWAY	BMP receptor signaling
0.0	3.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	4.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	20.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	1.3	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	26.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.4	12.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	12.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	7.8	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	6.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.3	20.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	3.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	10.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	6.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	2.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	3.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	5.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	4.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	3.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	1.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	4.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	1.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1	1.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	7.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	4.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	5.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.2	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	1.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	2.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	2.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	2.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Results for REL

Z-value: 2.74

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Transcription factors associated with REL

Activity-expression correlation:

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: