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avrg: Illumina Body Map 2 (GSE30611)

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Results for SOX1

Z-value: 0.68

Motif logo

Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
ENSG00000182968.5 SOX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg38_v1_chr13_+_112067143_1120671600.096.4e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_95069489 1.51 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr16_+_11965193 0.89 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr4_+_68815991 0.69 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chrX_+_106168297 0.68 ENST00000337685.6
ENST00000357175.6
PWWP domain containing 3B
chr19_+_35351552 0.68 ENST00000246553.3
free fatty acid receptor 1
chr11_-_47378479 0.64 ENST00000533968.1
Spi-1 proto-oncogene
chr16_+_11965234 0.62 ENST00000562385.1
TNF receptor superfamily member 17
chr3_-_58214671 0.54 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr3_-_171771295 0.53 ENST00000418087.1
phospholipase D1
chr1_-_144456805 0.51 ENST00000581897.6
ENST00000577412.5
NBPF member 15
chr11_-_47378391 0.50 ENST00000227163.8
Spi-1 proto-oncogene
chr2_+_188991663 0.49 ENST00000450867.1
collagen type III alpha 1 chain
chr17_-_31297231 0.48 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr1_-_111563956 0.46 ENST00000369717.8
transmembrane and immunoglobulin domain containing 3
chr12_-_9999176 0.43 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr1_+_32209074 0.41 ENST00000409358.2
doublecortin domain containing 2B
chr2_+_101998955 0.41 ENST00000393414.6
interleukin 1 receptor type 2
chr17_+_36064265 0.38 ENST00000616054.2
C-C motif chemokine ligand 18
chr1_-_200409976 0.38 ENST00000367352.3
zinc finger protein 281
chr17_-_40665121 0.38 ENST00000394052.5
keratin 222
chr1_-_12616762 0.37 ENST00000464917.5
dehydrogenase/reductase 3
chr1_-_52033772 0.36 ENST00000371614.2
KTI12 chromatin associated homolog
chr15_-_73753308 0.36 ENST00000569673.3
inhibitory synaptic factor 1
chr1_-_111563934 0.36 ENST00000443498.5
transmembrane and immunoglobulin domain containing 3
chr15_+_59611776 0.34 ENST00000396065.3
ENST00000560585.5
glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_+_11011640 0.33 ENST00000643396.1
solute carrier family 6 member 1
chr1_+_240091866 0.33 ENST00000319653.14
formin 2
chr1_-_200410001 0.32 ENST00000367353.2
zinc finger protein 281
chr6_-_138545685 0.32 ENST00000342260.9
NHS like 1
chr19_+_51761167 0.31 ENST00000340023.7
ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr6_+_130421086 0.30 ENST00000545622.5
transmembrane protein 200A
chr11_-_47378494 0.30 ENST00000533030.1
Spi-1 proto-oncogene
chr1_-_89175997 0.30 ENST00000294671.3
ENST00000650452.1
guanylate binding protein 7
chr1_+_12746192 0.29 ENST00000614859.5
chromosome 1 open reading frame 158
chr6_+_28281555 0.29 ENST00000259883.3
ENST00000682144.1
piggyBac transposable element derived 1
chr1_+_70411241 0.28 ENST00000370938.8
ENST00000346806.2
cystathionine gamma-lyase
chr8_-_109680812 0.28 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chr12_-_7695752 0.28 ENST00000329913.4
growth differentiation factor 3
chr9_+_5890872 0.27 ENST00000381477.8
ENST00000381476.5
ENST00000381471.1
melan-A
chr1_-_183653307 0.25 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chrX_-_72877864 0.25 ENST00000596389.5
DMRT like family C1
chr3_+_178558700 0.25 ENST00000432997.5
ENST00000455865.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr10_-_72217126 0.24 ENST00000317126.8
activating signal cointegrator 1 complex subunit 1
chr9_-_127847117 0.23 ENST00000480266.5
endoglin
chr4_-_170003738 0.23 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr9_-_101487120 0.23 ENST00000374848.8
post-GPI attachment to proteins GalNAc transferase 4
chr8_-_98942814 0.23 ENST00000519420.1
serine/threonine kinase 3
chr2_-_162318129 0.22 ENST00000679938.1
interferon induced with helicase C domain 1
chr7_+_36410510 0.22 ENST00000428612.5
anillin actin binding protein
chr7_-_106285898 0.21 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr8_+_144078590 0.20 ENST00000525936.1
exosome component 4
chr10_-_72216267 0.20 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
activating signal cointegrator 1 complex subunit 1
chr3_-_16482850 0.20 ENST00000432519.5
raftlin, lipid raft linker 1
chr14_+_61697622 0.20 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr18_+_24139053 0.20 ENST00000463087.5
ENST00000585037.5
ENST00000399496.8
ENST00000486759.6
ENST00000577705.1
ENST00000415309.6
ENST00000621648.4
ENST00000581397.5
calcium binding tyrosine phosphorylation regulated
chr1_+_184051678 0.19 ENST00000643231.1
tRNA splicing endonuclease subunit 15
chr9_-_13165442 0.19 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr3_+_138608851 0.18 ENST00000393035.6
Fas apoptotic inhibitory molecule
chr1_-_200410052 0.18 ENST00000294740.3
zinc finger protein 281
chr8_+_144078661 0.17 ENST00000316052.6
exosome component 4
chr3_-_190122317 0.17 ENST00000427335.6
prolyl 3-hydroxylase 2
chr20_+_50958805 0.17 ENST00000244051.3
molybdenum cofactor synthesis 3
chr7_-_105389365 0.16 ENST00000482897.5
SRSF protein kinase 2
chr1_+_174799895 0.16 ENST00000489615.5
RAB GTPase activating protein 1 like
chr3_+_126394890 0.16 ENST00000352312.6
cilia and flagella associated protein 100
chr3_+_128051610 0.15 ENST00000464451.5
SEC61 translocon subunit alpha 1
chr8_-_109608055 0.15 ENST00000529690.5
syntabulin
chr2_-_199456046 0.15 ENST00000428695.5
SATB homeobox 2
chr2_+_209580024 0.15 ENST00000392194.5
microtubule associated protein 2
chr22_-_30266839 0.15 ENST00000403463.1
ENST00000215781.3
oncostatin M
chr1_+_65147657 0.15 ENST00000546702.5
adenylate kinase 4
chr1_+_65147514 0.14 ENST00000545314.5
adenylate kinase 4
chr2_-_208190001 0.14 ENST00000451346.5
ENST00000341287.9
chromosome 2 open reading frame 80
chr1_-_86383078 0.14 ENST00000460698.6
outer dense fiber of sperm tails 2 like
chr11_-_113706292 0.13 ENST00000544634.5
ENST00000539732.5
ENST00000538770.1
ENST00000536856.5
ENST00000299882.11
ENST00000544476.1
transmembrane serine protease 5
chr19_-_6057271 0.13 ENST00000592281.5
regulatory factor X2
chr14_+_22501542 0.13 ENST00000390498.1
T cell receptor alpha joining 39
chr1_+_184051696 0.12 ENST00000533373.6
ENST00000647437.1
ENST00000647465.1
ENST00000645668.2
ENST00000645963.2
tRNA splicing endonuclease subunit 15
chr13_+_108596152 0.12 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr3_+_138608700 0.12 ENST00000360570.7
Fas apoptotic inhibitory molecule
chr12_-_120325936 0.12 ENST00000549767.1
phospholipase A2 group IB
chr17_+_82858519 0.12 ENST00000576160.6
ENST00000571712.5
tubulin folding cofactor D
chr1_+_184051643 0.12 ENST00000423085.7
ENST00000361641.6
tRNA splicing endonuclease subunit 15
chr5_-_55692731 0.11 ENST00000502247.1
solute carrier family 38 member 9
chr17_-_81166160 0.11 ENST00000326724.9
apoptosis associated tyrosine kinase
chrX_-_63755032 0.10 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr1_-_43172504 0.10 ENST00000431635.6
EBNA1 binding protein 2
chr19_+_52397841 0.10 ENST00000360465.8
ENST00000391788.6
ENST00000436397.5
ENST00000391787.6
ENST00000494167.6
ENST00000493272.5
zinc finger protein 528
chr13_-_21604145 0.10 ENST00000382374.9
ENST00000468222.2
mitochondrial calcium uptake 2
chr11_-_113706330 0.10 ENST00000540540.5
ENST00000538955.5
ENST00000545579.6
transmembrane serine protease 5
chr2_-_162318475 0.09 ENST00000648433.1
interferon induced with helicase C domain 1
chr2_-_96260575 0.09 ENST00000435268.1
transmembrane protein 127
chr3_+_138608575 0.09 ENST00000338446.8
Fas apoptotic inhibitory molecule
chr11_-_57410113 0.08 ENST00000529411.1
novel protein
chrX_-_63755187 0.08 ENST00000635729.1
ENST00000623566.3
Cdc42 guanine nucleotide exchange factor 9
chr2_-_208189985 0.08 ENST00000449053.1
chromosome 2 open reading frame 80
chr8_-_133489631 0.08 ENST00000523634.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr22_+_41952132 0.08 ENST00000381348.4
long intergenic non-protein coding RNA 634
chr11_-_134253248 0.08 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
thymocyte nuclear protein 1
chr7_+_142760398 0.07 ENST00000632998.1
serine protease 2
chr19_+_54874218 0.07 ENST00000355524.8
ENST00000391726.7
Fc fragment of IgA receptor
chr11_-_112260860 0.07 ENST00000338832.4
placenta expressed transcript 1
chr19_+_3762665 0.06 ENST00000330133.5
mitochondrial ribosomal protein L54
chr1_-_19251509 0.06 ENST00000375199.7
ENST00000375208.7
ENST00000477853.6
ER membrane protein complex subunit 1
chr3_+_158644510 0.06 ENST00000486715.6
ENST00000478576.5
ENST00000264263.9
ENST00000464732.1
G elongation factor mitochondrial 1
chr7_-_26200734 0.06 ENST00000354667.8
ENST00000618183.5
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_-_76669985 0.06 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr13_+_32316063 0.06 ENST00000680887.1
BRCA2 DNA repair associated
chr6_-_130222813 0.06 ENST00000437477.6
ENST00000439090.7
sterile alpha motif domain containing 3
chr19_+_38389612 0.05 ENST00000586301.5
sprouty related EVH1 domain containing 3
chr2_-_162318613 0.05 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr21_-_30561314 0.04 ENST00000334849.2
keratin associated protein 19-7
chr9_-_104536856 0.04 ENST00000641090.1
olfactory receptor family 13 subfamily C member 3
chrX_-_116462965 0.04 ENST00000371894.5
cancer/testis antigen 83
chr12_+_7304284 0.04 ENST00000399422.4
acyl-CoA synthetase medium chain family member 4
chr1_-_53940100 0.04 ENST00000371376.1
heat shock protein family B (small) member 11
chr2_+_170178136 0.04 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr8_-_92017292 0.04 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr6_+_123804141 0.04 ENST00000368416.5
sodium/potassium transporting ATPase interacting 2
chr14_+_22040576 0.03 ENST00000390448.3
T cell receptor alpha variable 20
chr12_-_64752871 0.03 ENST00000418919.6
glucosamine (N-acetyl)-6-sulfatase
chrX_-_120878924 0.03 ENST00000613352.1
novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)
chr15_+_42273194 0.03 ENST00000561871.1
glucosidase alpha, neutral C
chr11_-_33753394 0.03 ENST00000532057.5
ENST00000531080.5
F-box protein 3
chr11_+_5422111 0.03 ENST00000300778.4
olfactory receptor family 51 subfamily Q member 1
chr3_-_44477639 0.03 ENST00000396077.8
zinc finger protein 445
chr17_+_76732978 0.03 ENST00000587459.1
novel protein
chr2_+_201116396 0.02 ENST00000395148.6
CASP8 and FADD like apoptosis regulator
chr11_-_133845495 0.01 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr18_-_59318544 0.01 ENST00000587244.5
complexin 4
chr10_-_13972355 0.01 ENST00000264546.10
FERM domain containing 4A
chr4_-_163344832 0.01 ENST00000511901.1
neuropeptide Y receptor Y1
chr11_-_124313949 0.01 ENST00000641015.1
olfactory receptor family 8 subfamily D member 1
chr11_-_76670737 0.01 ENST00000260061.9
ENST00000404995.5
leucine rich repeat containing 32
chrX_+_22032427 0.00 ENST00000684143.1
phosphate regulating endopeptidase homolog X-linked
chr8_-_85378105 0.00 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr9_-_111328520 0.00 ENST00000374428.1
olfactory receptor family 2 subfamily K member 2
chr6_-_49969625 0.00 ENST00000398718.1
defensin beta 113
chr11_+_6863057 0.00 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr6_+_49499965 0.00 ENST00000545705.1
glycine-N-acyltransferase like 3
chr6_+_49499916 0.00 ENST00000371197.9
glycine-N-acyltransferase like 3
chr11_+_125626724 0.00 ENST00000531607.5
checkpoint kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 1.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.1 0.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0097229 sperm end piece(GO:0097229)
0.0 0.2 GO:0097545 axonemal outer doublet(GO:0097545)
0.0 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 1.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA