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avrg: Illumina Body Map 2 (GSE30611)

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Results for SOX17

Z-value: 1.80

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Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
SOX17
ENSG00000164736.6 SOX17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg38_v1_chr8_+_54457927_54457943-0.183.3e-01Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrY_+_2841864 7.43 ENST00000430575.1
RPS4Y1
ribosomal protein S4 Y-linked 1
chr12_-_110920568 5.58 ENST00000548438.1
ENST00000228841.15
MYL2
myosin light chain 2
chr11_-_118225002 2.83 ENST00000356289.10
ENST00000526620.5
JAML
junction adhesion molecule like
chr7_+_142352802 2.81 ENST00000634605.1
TRBV7-2
T cell receptor beta variable 7-2
chr12_-_110920710 2.62 ENST00000546404.1
MYL2
myosin light chain 2
chr11_-_116837586 2.58 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
APOA1
apolipoprotein A1
chr13_-_46211841 2.23 ENST00000442275.1
LCP1
lymphocyte cytosolic protein 1
chr8_-_17895487 2.19 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr1_+_40374648 2.02 ENST00000372708.5
SMAP2
small ArfGAP2
chr16_+_2817230 2.01 ENST00000005995.8
ENST00000574813.5
PRSS21
serine protease 21
chr3_-_52454032 1.99 ENST00000232975.8
TNNC1
troponin C1, slow skeletal and cardiac type
chrX_-_6535118 1.96 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
VCX3A
variable charge X-linked 3A
chr1_-_167090370 1.95 ENST00000367868.4
GPA33
glycoprotein A33
chr6_+_54099538 1.95 ENST00000447836.6
MLIP
muscular LMNA interacting protein
chr14_-_106301848 1.85 ENST00000390611.2
IGHV2-26
immunoglobulin heavy variable 2-26
chr3_+_111542178 1.84 ENST00000283285.10
ENST00000352690.9
CD96
CD96 molecule
chr16_+_33827140 1.83 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr8_-_17895403 1.81 ENST00000381840.5
ENST00000398054.5
FGL1
fibrinogen like 1
chr6_+_54099565 1.79 ENST00000511678.5
MLIP
muscular LMNA interacting protein
chrX_+_49331616 1.74 ENST00000612958.1
GAGE13
G antigen 13
chrX_+_49341192 1.73 ENST00000621907.1
GAGE2E
G antigen 2E
chr6_-_49787265 1.73 ENST00000304801.6
PGK2
phosphoglycerate kinase 2
chr12_+_101568350 1.72 ENST00000550514.5
MYBPC1
myosin binding protein C1
chr5_+_55102635 1.67 ENST00000274306.7
GZMA
granzyme A
chr1_-_160523204 1.65 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAMF6
SLAM family member 6
chr17_-_66229380 1.58 ENST00000205948.11
APOH
apolipoprotein H
chr15_+_76336755 1.57 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr1_+_158931539 1.57 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr14_-_106557465 1.53 ENST00000390625.3
IGHV3-49
immunoglobulin heavy variable 3-49
chr2_+_231592858 1.51 ENST00000313965.4
TEX44
testis expressed 44
chr9_-_35650902 1.51 ENST00000259608.8
ENST00000618781.1
SIT1
signaling threshold regulating transmembrane adaptor 1
chr2_-_157444044 1.50 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr11_+_94706412 1.47 ENST00000299004.13
AMOTL1
angiomotin like 1
chr14_+_21749163 1.46 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr11_+_60396435 1.44 ENST00000395005.6
MS4A14
membrane spanning 4-domains A14
chr7_+_142670734 1.44 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr4_-_73998669 1.43 ENST00000296027.5
CXCL5
C-X-C motif chemokine ligand 5
chr1_+_206897435 1.43 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
IL24
interleukin 24
chr2_+_181457342 1.40 ENST00000397033.7
ENST00000233573.6
ITGA4
integrin subunit alpha 4
chr19_-_19628512 1.40 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr3_+_158732183 1.39 ENST00000486568.5
ENST00000495318.5
MFSD1
ENSG00000240207.7
major facilitator superfamily domain containing 1
novel transcript, antisense to RARRES1
chr22_-_17773976 1.38 ENST00000317361.11
BID
BH3 interacting domain death agonist
chr3_+_111542134 1.38 ENST00000438817.6
CD96
CD96 molecule
chr1_+_15617415 1.37 ENST00000480945.6
DDI2
DNA damage inducible 1 homolog 2
chr17_-_57745292 1.36 ENST00000299415.3
CCDC182
coiled-coil domain containing 182
chr5_-_178187364 1.35 ENST00000463439.3
GMCL2
germ cell-less 2, spermatogenesis associated
chr19_+_6135635 1.35 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr1_+_46671821 1.35 ENST00000334122.5
ENST00000415500.1
TEX38
testis expressed 38
chr4_-_99144238 1.35 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr12_-_10409757 1.35 ENST00000309384.2
KLRC4
killer cell lectin like receptor C4
chr1_+_46671871 1.32 ENST00000564373.1
TEX38
testis expressed 38
chr14_-_70416973 1.32 ENST00000555276.5
ENST00000617124.4
COX16
SYNJ2BP-COX16
cytochrome c oxidase assembly factor COX16
SYNJ2BP-COX16 readthrough
chr22_+_22369601 1.31 ENST00000390295.3
IGLV7-46
immunoglobulin lambda variable 7-46
chr2_-_89222461 1.31 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr1_+_84408230 1.29 ENST00000370662.3
DNASE2B
deoxyribonuclease 2 beta
chr2_+_230225756 1.28 ENST00000373645.3
SP140
SP140 nuclear body protein
chr14_+_21712313 1.27 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr22_-_24555086 1.27 ENST00000447813.6
ENST00000402766.5
ENST00000435822.6
ENST00000407471.7
GUCD1
guanylyl cyclase domain containing 1
chr22_-_24555845 1.26 ENST00000407973.2
GUCD1
guanylyl cyclase domain containing 1
chr6_-_132757883 1.26 ENST00000525289.5
ENST00000326499.11
VNN2
vanin 2
chr7_+_138076453 1.24 ENST00000242375.8
ENST00000411726.6
AKR1D1
aldo-keto reductase family 1 member D1
chr7_+_142529268 1.22 ENST00000612787.1
TRBV7-9
T cell receptor beta variable 7-9
chrX_-_135799001 1.21 ENST00000612878.4
CT45A6
cancer/testis antigen family 45 member A6
chr17_-_38841438 1.21 ENST00000614158.2
C17orf98
chromosome 17 open reading frame 98
chr14_+_103563024 1.21 ENST00000495778.1
COA8
cytochrome c oxidase assembly factor 8
chr1_+_172452885 1.20 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr14_-_106511856 1.20 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr19_+_15508517 1.20 ENST00000269703.8
CYP4F22
cytochrome P450 family 4 subfamily F member 22
chr1_-_6602885 1.18 ENST00000377663.3
KLHL21
kelch like family member 21
chr12_-_389249 1.18 ENST00000535014.5
ENST00000543507.1
ENST00000544760.1
ENST00000399788.7
KDM5A
lysine demethylase 5A
chr8_-_37940103 1.18 ENST00000524298.1
ENST00000307599.5
GOT1L1
glutamic-oxaloacetic transaminase 1 like 1
chrX_+_49322057 1.17 ENST00000442437.2
GAGE12J
G antigen 12J
chr1_+_174875505 1.16 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr3_+_46370854 1.14 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chrX_-_8171267 1.14 ENST00000317103.5
VCX2
variable charge X-linked 2
chr18_+_9885726 1.14 ENST00000611534.1
ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2
chr19_+_3933059 1.13 ENST00000616156.4
ENST00000168977.6
ENST00000599576.5
NMRK2
nicotinamide riboside kinase 2
chr2_+_90082635 1.12 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr3_-_123992046 1.12 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
ROPN1
rhophilin associated tail protein 1
chr14_-_106771020 1.12 ENST00000617374.2
IGHV2-70
immunoglobulin heavy variable 2-70
chr22_-_24555920 1.11 ENST00000621833.4
ENST00000404664.7
GUCD1
guanylyl cyclase domain containing 1
chr7_+_142587857 1.11 ENST00000617639.1
TRBV14
T cell receptor beta variable 14
chr1_+_158831323 1.10 ENST00000368141.5
MNDA
myeloid cell nuclear differentiation antigen
chr2_-_215138603 1.10 ENST00000272895.12
ABCA12
ATP binding cassette subfamily A member 12
chr1_-_92483947 1.10 ENST00000370332.5
GFI1
growth factor independent 1 transcriptional repressor
chr5_+_111223614 1.08 ENST00000508074.5
CAMK4
calcium/calmodulin dependent protein kinase IV
chr14_-_54902807 1.07 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GCH1
GTP cyclohydrolase 1
chr7_+_138076422 1.07 ENST00000432161.5
AKR1D1
aldo-keto reductase family 1 member D1
chr11_-_118252279 1.07 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
MPZL3
myelin protein zero like 3
chr7_-_81770428 1.07 ENST00000421558.1
HGF
hepatocyte growth factor
chr14_+_22123318 1.06 ENST00000390455.3
TRAV26-1
T cell receptor alpha variable 26-1
chr19_+_2163915 1.05 ENST00000398665.8
DOT1L
DOT1 like histone lysine methyltransferase
chr19_-_15479469 1.04 ENST00000292609.8
ENST00000340880.5
PGLYRP2
peptidoglycan recognition protein 2
chr14_-_106724093 1.04 ENST00000390634.3
IGHV2-70D
immunoglobulin heavy variable 2-70D
chr14_+_21825453 1.03 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr1_-_153945225 1.03 ENST00000368646.6
DENND4B
DENN domain containing 4B
chr6_+_31572279 1.02 ENST00000418386.3
LTA
lymphotoxin alpha
chr2_-_89040745 1.02 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr2_+_181457198 1.02 ENST00000339307.8
ITGA4
integrin subunit alpha 4
chr10_-_125683106 1.02 ENST00000532135.5
ENST00000526819.5
TEX36
testis expressed 36
chr14_+_22202561 1.01 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr7_-_117427487 1.01 ENST00000284629.7
ASZ1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr12_+_69348372 1.01 ENST00000261267.7
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr19_+_43716095 1.00 ENST00000596627.1
IRGC
immunity related GTPase cinema
chr10_+_22321056 0.99 ENST00000376663.8
BMI1
BMI1 proto-oncogene, polycomb ring finger
chr1_-_197775633 0.99 ENST00000422998.1
DENND1B
DENN domain containing 1B
chr19_+_16661121 0.98 ENST00000187762.7
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr3_-_123991352 0.98 ENST00000184183.8
ROPN1
rhophilin associated tail protein 1
chr11_+_60378524 0.97 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
MS4A7
MS4A14
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr10_-_125683155 0.96 ENST00000368821.4
TEX36
testis expressed 36
chr19_+_54593619 0.96 ENST00000251372.8
ENST00000453777.1
LILRA1
leukocyte immunoglobulin like receptor A1
chr6_+_83859640 0.95 ENST00000369679.4
ENST00000369681.10
CYB5R4
cytochrome b5 reductase 4
chr12_+_10010627 0.95 ENST00000338896.11
ENST00000396502.5
CLEC12B
C-type lectin domain family 12 member B
chr1_+_207496229 0.95 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr7_-_122304738 0.94 ENST00000442488.7
FEZF1
FEZ family zinc finger 1
chr16_+_31355215 0.94 ENST00000562522.2
ITGAX
integrin subunit alpha X
chr8_-_7452365 0.94 ENST00000458665.5
ENST00000528168.3
SPAG11B
sperm associated antigen 11B
chr2_+_102418642 0.94 ENST00000264260.6
IL18RAP
interleukin 18 receptor accessory protein
chr21_+_29300111 0.93 ENST00000451655.5
BACH1
BTB domain and CNC homolog 1
chr15_-_19988117 0.93 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr19_+_15010720 0.93 ENST00000292574.4
CCDC105
coiled-coil domain containing 105
chr19_+_43716070 0.91 ENST00000244314.6
IRGC
immunity related GTPase cinema
chr2_+_43838963 0.89 ENST00000272286.4
ABCG8
ATP binding cassette subfamily G member 8
chr2_-_89117844 0.89 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr9_+_132978687 0.89 ENST00000372122.4
ENST00000372123.5
GFI1B
growth factor independent 1B transcriptional repressor
chrX_+_8464830 0.88 ENST00000453306.4
ENST00000381032.6
ENST00000444481.3
VCX3B
variable charge X-linked 3B
chr14_-_105065422 0.88 ENST00000329797.8
ENST00000539291.6
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr1_-_6602859 0.88 ENST00000377658.8
KLHL21
kelch like family member 21
chr3_+_125969172 0.88 ENST00000514116.6
ENST00000513830.5
ROPN1B
rhophilin associated tail protein 1B
chr2_+_210477708 0.87 ENST00000673711.1
CPS1
carbamoyl-phosphate synthase 1
chr19_+_54630497 0.86 ENST00000396332.8
ENST00000427581.6
LILRB1
leukocyte immunoglobulin like receptor B1
chr3_-_15498548 0.86 ENST00000605797.1
COLQ
collagen like tail subunit of asymmetric acetylcholinesterase
chr6_+_31571957 0.86 ENST00000454783.5
LTA
lymphotoxin alpha
chr1_+_207496268 0.86 ENST00000529814.1
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr2_+_90172802 0.86 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr8_-_51809414 0.85 ENST00000356297.5
PXDNL
peroxidasin like
chr10_+_128047406 0.85 ENST00000467366.1
PTPRE
protein tyrosine phosphatase receptor type E
chr3_+_125969214 0.84 ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr2_-_88947820 0.84 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr2_+_90004792 0.83 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr3_+_98732688 0.83 ENST00000486334.6
ENST00000394162.5
ENST00000613264.4
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr19_-_4902854 0.82 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr15_-_72272999 0.82 ENST00000568360.5
PARP6
poly(ADP-ribose) polymerase family member 6
chr5_+_76875177 0.82 ENST00000613039.1
S100Z
S100 calcium binding protein Z
chr1_+_197912462 0.82 ENST00000475727.1
ENST00000367391.5
ENST00000367390.7
LHX9
LIM homeobox 9
chrX_-_135764444 0.81 ENST00000597510.6
CT45A3
cancer/testis antigen family 45 member A3
chr14_+_20768393 0.80 ENST00000326783.4
EDDM3B
epididymal protein 3B
chr22_+_44181357 0.80 ENST00000417767.1
PARVG
parvin gamma
chr2_-_37188670 0.80 ENST00000535679.6
SULT6B1
sulfotransferase family 6B member 1
chr11_+_57542641 0.80 ENST00000527972.5
ENST00000399154.3
SMTNL1
smoothelin like 1
chr18_+_24460655 0.80 ENST00000426880.2
HRH4
histamine receptor H4
chrY_-_24047969 0.79 ENST00000306882.4
ENST00000382407.1
CDY1B
chromodomain Y-linked 1B
chr11_-_123885627 0.79 ENST00000528595.1
ENST00000375026.7
TMEM225
transmembrane protein 225
chr14_-_106235582 0.78 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chrX_-_135781729 0.78 ENST00000617203.1
CT45A5
cancer/testis antigen family 45 member A5
chrY_-_17880220 0.78 ENST00000382867.4
CDY2B
chromodomain Y-linked 2B
chr19_+_41576206 0.78 ENST00000187608.13
CEACAM21
CEA cell adhesion molecule 21
chr1_+_207496147 0.78 ENST00000400960.7
ENST00000367049.9
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr4_-_69495897 0.77 ENST00000305107.7
ENST00000639621.1
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr9_-_136748515 0.77 ENST00000341206.9
LCN6
lipocalin 6
chr7_+_139829242 0.77 ENST00000455353.6
ENST00000458722.6
ENST00000448866.7
ENST00000411653.6
TBXAS1
thromboxane A synthase 1
chr3_+_98732430 0.77 ENST00000497008.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr5_-_16508858 0.77 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr19_+_3933581 0.76 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr1_+_202214072 0.75 ENST00000439764.2
LGR6
leucine rich repeat containing G protein-coupled receptor 6
chr2_+_227325151 0.75 ENST00000423098.5
MFF
mitochondrial fission factor
chr19_+_41376560 0.73 ENST00000436170.6
TMEM91
transmembrane protein 91
chr1_+_222739670 0.73 ENST00000456298.5
FAM177B
family with sequence similarity 177 member B
chr12_+_8992029 0.73 ENST00000543895.1
KLRG1
killer cell lectin like receptor G1
chr6_+_88047822 0.72 ENST00000237201.2
SPACA1
sperm acrosome associated 1
chr2_-_88992903 0.72 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr5_-_55692620 0.72 ENST00000503817.5
ENST00000512595.5
SLC38A9
solute carrier family 38 member 9
chr9_-_94328644 0.72 ENST00000341207.5
ENST00000253262.9
NUTM2F
NUT family member 2F
chr17_-_74531467 0.71 ENST00000314401.3
ENST00000392621.6
CD300LB
CD300 molecule like family member b
chr5_-_16508990 0.71 ENST00000399793.6
RETREG1
reticulophagy regulator 1
chr19_+_54769785 0.71 ENST00000336077.11
KIR2DL1
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
chr13_-_46182136 0.70 ENST00000323076.7
LCP1
lymphocyte cytosolic protein 1
chr17_-_4949037 0.70 ENST00000572383.1
PFN1
profilin 1
chr4_-_69495861 0.69 ENST00000512583.5
UGT2B4
UDP glucuronosyltransferase family 2 member B4
chr10_+_11005301 0.68 ENST00000416382.6
ENST00000631460.1
ENST00000631816.1
CELF2
CUGBP Elav-like family member 2
chr19_+_34404379 0.68 ENST00000246535.4
PDCD2L
programmed cell death 2 like
chr4_+_68815991 0.67 ENST00000265403.12
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase family 2 member B10
chr19_+_41376692 0.67 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
TMEM91
ENSG00000255730.5
transmembrane protein 91
novel protein
chr17_-_74361860 0.67 ENST00000375366.4
BTBD17
BTB domain containing 17
chrX_-_135868069 0.66 ENST00000604569.1
CT45A9
cancer/testis antigen family 45 member A9
chr11_+_60378494 0.66 ENST00000534016.5
MS4A7
membrane spanning 4-domains A7
chr3_+_98732236 0.65 ENST00000265261.10
ENST00000483910.5
ENST00000460774.5
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr3_-_45958654 0.65 ENST00000438446.1
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1
chr2_+_86441341 0.63 ENST00000312912.10
ENST00000409064.5
KDM3A
lysine demethylase 3A
chr12_-_124914056 0.63 ENST00000541272.1
ENST00000535131.1
UBC
ubiquitin C
chr20_-_63568074 0.62 ENST00000427522.6
HELZ2
helicase with zinc finger 2
chr6_-_31357171 0.62 ENST00000412585.7
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr5_+_139342442 0.61 ENST00000394795.6
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chrX_-_135850791 0.61 ENST00000611438.1
CT45A8
cancer/testis antigen family 45 member A8
chr7_-_115968302 0.61 ENST00000457268.5
TFEC
transcription factor EC
chr17_-_59964714 0.61 ENST00000589113.1
ENST00000305783.13
RNFT1
ring finger protein, transmembrane 1
chr1_-_145995713 0.61 ENST00000425134.2
TXNIP
thioredoxin interacting protein
chr17_-_5234801 0.60 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr1_+_13254212 0.60 ENST00000622421.2
PRAMEF5
PRAME family member 5
chr22_+_44069043 0.59 ENST00000404989.1
PARVB
parvin beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.9 2.6 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.7 2.6 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.6 8.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.6 1.9 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.6 1.7 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.5 1.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.5 2.6 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.5 2.0 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.5 1.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 1.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.5 2.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5 2.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.4 1.2 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.4 1.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 1.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.4 1.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.3 1.0 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 1.0 GO:0003032 detection of oxygen(GO:0003032)
0.3 2.8 GO:0035696 monocyte extravasation(GO:0035696)
0.3 0.9 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 0.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 1.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 0.9 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.2 1.1 GO:0035627 ceramide transport(GO:0035627)
0.2 0.9 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.2 1.2 GO:0034721 negative regulation of histone deacetylation(GO:0031064) histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.2 1.5 GO:0061709 reticulophagy(GO:0061709)
0.2 0.5 GO:0036245 cellular response to menadione(GO:0036245)
0.2 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 0.5 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.2 0.9 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:1990523 bone regeneration(GO:1990523)
0.1 0.9 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 1.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 2.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.7 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
0.1 0.7 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 8.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.5 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 1.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 1.6 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.3 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 1.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 2.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 6.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 2.3 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.2 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 2.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.4 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 7.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0045007 depurination(GO:0045007)
0.0 1.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 4.0 GO:0030317 sperm motility(GO:0030317)
0.0 0.5 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 1.0 GO:0007379 segment specification(GO:0007379)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 1.0 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 1.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.3 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0060011 progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 1.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 4.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.6 GO:0002347 response to tumor cell(GO:0002347)
0.0 1.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 2.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.8 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.8 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 1.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.6 2.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 2.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 8.2 GO:0097512 cardiac myofibril(GO:0097512)
0.3 3.1 GO:0005827 polar microtubule(GO:0005827)
0.3 3.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 8.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.0 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0071547 piP-body(GO:0071547)
0.1 0.4 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.5 GO:0005713 recombination nodule(GO:0005713)
0.1 7.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525) NF-kappaB complex(GO:0071159)
0.1 1.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 2.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.7 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 4.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 4.3 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.6 1.7 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.5 3.7 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.5 1.9 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.5 2.3 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.4 2.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.4 1.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 1.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.3 8.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 1.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 2.4 GO:1990405 protein antigen binding(GO:1990405)
0.3 1.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.0 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.3 0.8 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 1.3 GO:0035276 ethanol binding(GO:0035276)
0.2 0.9 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.9 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.2 2.0 GO:0031013 troponin I binding(GO:0031013)
0.2 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 0.5 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.1 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 8.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 1.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.7 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750)
0.1 6.8 GO:0019843 rRNA binding(GO:0019843)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.2 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 11.5 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.9 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.6 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 2.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0050560 aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 4.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 11.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 7.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 5.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters