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avrg: Illumina Body Map 2 (GSE30611)
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Results for SOX3_SOX2
Z-value: 3.59
Motif logo
Transcription factors associated with SOX3_SOX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SOX3
|
ENSG00000134595.9 | SOX3 |
|
SOX2
|
ENSG00000181449.4 | SOX2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX2 | hg38_v1_chr3_+_181711915_181711934 | 0.70 | 9.1e-06 | Click! |
| SOX3 | hg38_v1_chrX_-_140505058_140505076 | 0.60 | 2.9e-04 | Click! |
Activity profile of SOX3_SOX2 motif
Sorted Z-values of SOX3_SOX2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX3_SOX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 43.5 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 2.9 | 14.4 | GO:1901202 | negative regulation of extracellular matrix assembly(GO:1901202) |
| 2.9 | 11.4 | GO:1904616 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 2.5 | 7.4 | GO:0043397 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) |
| 2.1 | 12.4 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 2.0 | 13.8 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
| 1.7 | 5.2 | GO:0042323 | negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 1.7 | 5.1 | GO:1904397 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 1.7 | 25.0 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 1.5 | 4.5 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 1.3 | 5.2 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 1.3 | 3.8 | GO:0070662 | mast cell proliferation(GO:0070662) |
| 1.3 | 8.8 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.2 | 7.2 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 1.2 | 9.2 | GO:1902847 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 1.1 | 3.4 | GO:0008057 | eye pigment granule organization(GO:0008057) |
| 1.1 | 4.5 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 1.1 | 3.3 | GO:2000584 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 1.1 | 3.2 | GO:0006683 | galactosylceramide catabolic process(GO:0006683) |
| 1.0 | 8.2 | GO:1902731 | negative regulation of chondrocyte proliferation(GO:1902731) |
| 1.0 | 11.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 1.0 | 8.0 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.9 | 2.8 | GO:0007037 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.9 | 23.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.8 | 3.2 | GO:1903281 | positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 0.8 | 2.3 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.8 | 4.7 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.8 | 2.3 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
| 0.8 | 3.8 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
| 0.7 | 8.0 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.7 | 2.1 | GO:1901069 | guanosine-containing compound catabolic process(GO:1901069) |
| 0.7 | 2.1 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 0.7 | 2.0 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751) |
| 0.7 | 7.3 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.6 | 4.5 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.6 | 2.5 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.6 | 0.6 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.6 | 7.6 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.6 | 3.5 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.6 | 2.2 | GO:0048691 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 0.6 | 6.6 | GO:0060125 | habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125) |
| 0.5 | 8.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.5 | 1.1 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.5 | 6.9 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.5 | 3.1 | GO:1902988 | neurofibrillary tangle assembly(GO:1902988) |
| 0.5 | 1.0 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.5 | 2.0 | GO:0009258 | 10-formyltetrahydrofolate catabolic process(GO:0009258) |
| 0.5 | 3.4 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.5 | 8.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.5 | 6.2 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.5 | 8.4 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.4 | 4.5 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.4 | 2.2 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
| 0.4 | 9.8 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.4 | 3.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.4 | 3.5 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 1.3 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 0.4 | 6.5 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.4 | 1.7 | GO:1901318 | negative regulation of sperm motility(GO:1901318) |
| 0.4 | 4.6 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.4 | 1.7 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.4 | 6.0 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.4 | 6.8 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.4 | 2.4 | GO:0008615 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 0.4 | 1.9 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.4 | 2.7 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.4 | 5.6 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.4 | 3.3 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.4 | 2.6 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.4 | 16.5 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.4 | 1.1 | GO:2000559 | CD24 biosynthetic process(GO:0035724) activation of meiosis involved in egg activation(GO:0060466) negative regulation of monocyte extravasation(GO:2000438) regulation of CD24 biosynthetic process(GO:2000559) positive regulation of CD24 biosynthetic process(GO:2000560) |
| 0.4 | 4.7 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
| 0.4 | 10.0 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.3 | 1.4 | GO:0005989 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 0.3 | 1.7 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.3 | 1.4 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.3 | 1.4 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.3 | 3.1 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.3 | 1.0 | GO:0034183 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.3 | 5.3 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 11.5 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.3 | 1.0 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.3 | 5.1 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.3 | 0.9 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 0.3 | 14.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.3 | 1.2 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.3 | 3.1 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.3 | 0.9 | GO:0045175 | basal protein localization(GO:0045175) |
| 0.3 | 2.4 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.3 | 1.5 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 0.3 | 0.3 | GO:1904798 | regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798) |
| 0.3 | 1.8 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.3 | 0.9 | GO:0061364 | apoptotic process involved in luteolysis(GO:0061364) |
| 0.3 | 7.5 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.3 | 2.4 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.3 | 0.6 | GO:0061740 | protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) |
| 0.3 | 1.4 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.3 | 4.3 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.3 | 2.6 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 0.3 | 1.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.3 | 2.2 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 1.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.3 | 1.6 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.3 | 1.9 | GO:0033029 | regulation of neutrophil apoptotic process(GO:0033029) |
| 0.3 | 6.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.3 | 3.5 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.3 | 0.8 | GO:1901389 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 0.3 | 1.8 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503) |
| 0.3 | 1.0 | GO:0021538 | epithalamus development(GO:0021538) habenula development(GO:0021986) |
| 0.3 | 1.0 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.3 | 4.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 2.7 | GO:0098907 | protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.2 | 2.7 | GO:0003172 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025) |
| 0.2 | 1.7 | GO:0030421 | defecation(GO:0030421) |
| 0.2 | 0.7 | GO:0015847 | putrescine transport(GO:0015847) |
| 0.2 | 0.5 | GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.2 | 3.2 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 0.2 | 4.1 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.2 | 2.7 | GO:2000582 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.2 | 1.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.2 | 5.5 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.2 | 4.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 1.2 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.2 | 4.3 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.2 | 1.4 | GO:1904179 | regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179) |
| 0.2 | 2.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.2 | 1.2 | GO:1901994 | negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.2 | 1.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 4.5 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
| 0.2 | 0.7 | GO:0060128 | corticotropin hormone secreting cell differentiation(GO:0060128) |
| 0.2 | 7.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 0.9 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.2 | 3.7 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.2 | 7.8 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.2 | 2.2 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
| 0.2 | 1.9 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 5.9 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.2 | 1.9 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.2 | 1.0 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 0.2 | 0.6 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.2 | 0.2 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.2 | 2.8 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.2 | 5.5 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.2 | 0.8 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.2 | 1.0 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 0.2 | 0.6 | GO:0036304 | umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) |
| 0.2 | 1.4 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.2 | 1.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.2 | 0.6 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.2 | 1.9 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.2 | 1.7 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.2 | 2.1 | GO:0071205 | protein localization to juxtaparanode region of axon(GO:0071205) |
| 0.2 | 2.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 12.0 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.2 | 3.1 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.2 | 0.7 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.2 | 3.6 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.2 | 1.2 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.2 | 1.6 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.2 | 4.4 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181) |
| 0.2 | 1.1 | GO:0032902 | nerve growth factor production(GO:0032902) |
| 0.2 | 2.3 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.2 | 2.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 0.5 | GO:0043438 | acetoacetic acid metabolic process(GO:0043438) |
| 0.2 | 1.0 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.2 | 1.6 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.2 | 1.9 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.2 | 1.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.2 | 0.5 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.2 | 0.5 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.2 | 3.2 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.2 | 1.0 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.2 | 2.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.2 | 2.5 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.2 | 0.5 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.2 | 2.6 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.2 | 3.9 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.2 | 0.5 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.2 | 0.8 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.2 | 9.1 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.2 | 6.0 | GO:0006833 | water transport(GO:0006833) |
| 0.2 | 1.6 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.2 | 2.9 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.2 | 4.8 | GO:0042749 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.2 | 2.8 | GO:0021984 | adenohypophysis development(GO:0021984) |
| 0.2 | 1.4 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.2 | 1.1 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 0.2 | 2.2 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.2 | 5.9 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.2 | 6.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.2 | 1.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.2 | 1.8 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
| 0.2 | 3.0 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.2 | 3.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 0.6 | GO:0032595 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 0.1 | 0.7 | GO:0035927 | RNA import into mitochondrion(GO:0035927) |
| 0.1 | 2.2 | GO:0046838 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 3.7 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.1 | 0.6 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 0.1 | 1.8 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 2.8 | GO:0045162 | neuronal action potential propagation(GO:0019227) clustering of voltage-gated sodium channels(GO:0045162) action potential propagation(GO:0098870) |
| 0.1 | 0.6 | GO:1900025 | negative regulation of substrate adhesion-dependent cell spreading(GO:1900025) |
| 0.1 | 3.2 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.9 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 0.6 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
| 0.1 | 1.1 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.1 | 0.4 | GO:0060739 | mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739) |
| 0.1 | 1.1 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.1 | 3.5 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 3.7 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.1 | 2.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 2.0 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.1 | 1.1 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 0.1 | 1.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.7 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 0.8 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.1 | 3.7 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 0.8 | GO:1901911 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 0.1 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.1 | 1.3 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 0.4 | GO:0046707 | IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709) |
| 0.1 | 0.7 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.1 | 1.1 | GO:0061589 | calcium activated phosphatidylserine scrambling(GO:0061589) |
| 0.1 | 2.1 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 2.7 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 3.6 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 5.0 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 17.2 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.1 | 0.8 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 4.1 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.6 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.1 | 0.9 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 2.4 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 1.0 | GO:0043305 | negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305) |
| 0.1 | 1.4 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.5 | GO:0007343 | egg activation(GO:0007343) |
| 0.1 | 24.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 4.9 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 1.3 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.1 | 2.4 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 6.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.5 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.1 | 1.9 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.1 | 0.2 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 8.5 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.2 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.1 | 0.4 | GO:2000395 | positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.1 | 2.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.5 | GO:0050651 | dermatan sulfate proteoglycan biosynthetic process(GO:0050651) |
| 0.1 | 4.7 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.1 | 0.7 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
| 0.1 | 0.8 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.1 | 0.8 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 1.7 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 0.8 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.1 | 1.2 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.1 | 4.1 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.1 | 1.0 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 0.4 | GO:0071321 | cellular response to cGMP(GO:0071321) |
| 0.1 | 1.3 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 2.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.1 | 6.3 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 0.5 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.1 | 4.6 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.1 | 0.6 | GO:0035754 | B cell chemotaxis(GO:0035754) |
| 0.1 | 0.9 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.1 | 0.2 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.1 | 11.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 0.8 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.1 | 1.1 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 3.8 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 1.2 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.7 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.8 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.1 | 0.6 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.1 | 0.7 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 2.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 1.3 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.1 | 1.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.1 | 0.6 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) |
| 0.1 | 0.7 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.1 | 0.5 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.1 | 0.5 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.1 | 1.8 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.1 | 0.5 | GO:1903286 | regulation of potassium ion import(GO:1903286) |
| 0.1 | 2.0 | GO:2000463 | positive regulation of excitatory postsynaptic potential(GO:2000463) |
| 0.1 | 0.8 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.1 | 0.8 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.1 | 0.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.1 | 0.3 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.1 | 1.3 | GO:1900271 | regulation of long-term synaptic potentiation(GO:1900271) |
| 0.1 | 2.1 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.8 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.1 | 1.9 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.1 | 0.7 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.1 | 0.2 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 0.1 | 1.0 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.2 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.1 | 2.1 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 0.7 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 5.9 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.1 | 3.9 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
| 0.1 | 3.6 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.1 | 0.2 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.1 | 0.4 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 2.7 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.1 | 1.7 | GO:0015865 | purine nucleotide transport(GO:0015865) |
| 0.1 | 0.6 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.1 | 0.9 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.1 | 1.1 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 4.1 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.1 | 2.2 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.1 | 0.5 | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
| 0.1 | 1.6 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.1 | 3.4 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.1 | 0.3 | GO:0051037 | regulation of transcription involved in meiotic cell cycle(GO:0051037) |
| 0.1 | 0.9 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.1 | 0.4 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.2 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.1 | 0.8 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.1 | GO:0018277 | protein deamination(GO:0018277) |
| 0.1 | 2.1 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.1 | 0.3 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.1 | 2.2 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 0.5 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.2 | GO:0007060 | male meiosis chromosome segregation(GO:0007060) |
| 0.1 | 0.5 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.1 | 0.7 | GO:1902284 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.1 | 0.4 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 3.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 0.3 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.1 | 1.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.1 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.1 | 0.2 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.1 | 2.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.1 | 1.5 | GO:0009437 | carnitine metabolic process(GO:0009437) |
| 0.1 | 1.4 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.1 | 2.2 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.8 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.1 | 0.4 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.1 | 0.9 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.1 | 0.6 | GO:2000618 | regulation of histone H4-K16 acetylation(GO:2000618) |
| 0.1 | 0.6 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.1 | 0.5 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.1 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.2 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 0.1 | 0.2 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.1 | 1.9 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.1 | 0.4 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.1 | 0.3 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.1 | 2.9 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.1 | 0.5 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.1 | 0.2 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.1 | 0.9 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.1 | 0.3 | GO:0019474 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.1 | 0.5 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.1 | 0.2 | GO:0031952 | regulation of protein autophosphorylation(GO:0031952) |
| 0.1 | 2.2 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.0 | 0.1 | GO:0050976 | sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) |
| 0.0 | 0.2 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.0 | 0.3 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.0 | 0.6 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 1.0 | GO:0050812 | regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.3 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.0 | 5.0 | GO:0061337 | cardiac conduction(GO:0061337) |
| 0.0 | 0.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.7 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.0 | 0.6 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 0.0 | 0.8 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.0 | 0.4 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) regulation of dendritic cell chemotaxis(GO:2000508) |
| 0.0 | 0.4 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.0 | 0.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.4 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.7 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.0 | 1.2 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 1.5 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 1.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.0 | 0.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 0.2 | GO:0045872 | regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.0 | 1.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.5 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.0 | 0.1 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 0.0 | 0.4 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 3.7 | GO:0051298 | centrosome duplication(GO:0051298) |
| 0.0 | 0.3 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) |
| 0.0 | 2.4 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.0 | 0.4 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.0 | 0.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.0 | 0.4 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.0 | 0.2 | GO:0006382 | adenosine to inosine editing(GO:0006382) |
| 0.0 | 2.8 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.3 | GO:0009597 | detection of virus(GO:0009597) |
| 0.0 | 0.1 | GO:0089718 | amino acid import across plasma membrane(GO:0089718) |
| 0.0 | 0.4 | GO:0051882 | mitochondrial depolarization(GO:0051882) regulation of mitochondrial depolarization(GO:0051900) |
| 0.0 | 1.3 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.0 | 0.1 | GO:1904752 | vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752) |
| 0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.2 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.9 | GO:0006312 | mitotic recombination(GO:0006312) |
| 0.0 | 1.8 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.8 | GO:0090004 | positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.0 | 1.3 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.1 | GO:1990418 | response to insulin-like growth factor stimulus(GO:1990418) |
| 0.0 | 0.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.4 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.0 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 3.0 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.0 | 0.9 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.2 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.0 | 4.5 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.0 | 0.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.0 | 0.1 | GO:0033320 | UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320) |
| 0.0 | 1.6 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.9 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.1 | GO:0090118 | canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) |
| 0.0 | 0.5 | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.9 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.0 | 4.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.3 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 1.3 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 0.1 | GO:1904247 | positive regulation of polynucleotide adenylyltransferase activity(GO:1904247) |
| 0.0 | 0.4 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 1.4 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.0 | 0.1 | GO:0035711 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) |
| 0.0 | 2.3 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 3.4 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 0.2 | GO:0046607 | positive regulation of mitotic centrosome separation(GO:0046604) positive regulation of centrosome cycle(GO:0046607) |
| 0.0 | 1.3 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 0.5 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 0.2 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
| 0.0 | 0.4 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.2 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.0 | 1.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.1 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.0 | 0.5 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.1 | GO:1903336 | intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642) |
| 0.0 | 0.5 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
| 0.0 | 1.1 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 0.0 | 0.1 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
| 0.0 | 0.3 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 0.1 | GO:0090299 | regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.0 | 0.1 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.0 | 0.6 | GO:0010644 | cell communication by electrical coupling(GO:0010644) |
| 0.0 | 0.2 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.0 | 2.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 1.4 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
| 0.0 | 0.3 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.5 | GO:0001975 | response to amphetamine(GO:0001975) |
| 0.0 | 1.6 | GO:0035308 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 1.5 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.2 | GO:0015820 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.0 | 0.3 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.0 | 0.8 | GO:0010737 | protein kinase A signaling(GO:0010737) |
| 0.0 | 0.6 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.2 | GO:0055048 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.0 | 0.7 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 0.3 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.5 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.1 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 0.0 | GO:0060796 | regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) |
| 0.0 | 2.2 | GO:0001764 | neuron migration(GO:0001764) |
| 0.0 | 0.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.1 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.0 | 0.1 | GO:1901355 | cellular response to rapamycin(GO:0072752) response to rapamycin(GO:1901355) |
| 0.0 | 0.1 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 0.1 | GO:0060453 | regulation of gastric acid secretion(GO:0060453) |
| 0.0 | 0.5 | GO:0060260 | regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) |
| 0.0 | 0.5 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 0.4 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.0 | 0.1 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.0 | 0.0 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 0.0 | 0.2 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.3 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.0 | 0.1 | GO:0051383 | kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
| 0.0 | 0.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.0 | 0.0 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.0 | 0.1 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
| 0.0 | 0.6 | GO:0042304 | regulation of fatty acid biosynthetic process(GO:0042304) |
| 0.0 | 0.2 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.0 | 0.6 | GO:0009247 | glycolipid biosynthetic process(GO:0009247) |
| 0.0 | 0.3 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.1 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.1 | GO:0030007 | cellular potassium ion homeostasis(GO:0030007) |
| 0.0 | 0.3 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.0 | 1.2 | GO:0008652 | cellular amino acid biosynthetic process(GO:0008652) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 34.4 | GO:0033269 | internode region of axon(GO:0033269) |
| 2.8 | 11.3 | GO:0097229 | sperm end piece(GO:0097229) |
| 2.6 | 7.9 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 1.5 | 16.9 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.9 | 7.8 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.8 | 4.7 | GO:0044393 | microspike(GO:0044393) |
| 0.7 | 12.1 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.6 | 3.7 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.5 | 8.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.5 | 3.1 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.5 | 0.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.5 | 8.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.5 | 2.9 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.5 | 2.4 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.5 | 1.4 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.5 | 1.8 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.4 | 11.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.4 | 4.7 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.4 | 3.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.4 | 2.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.4 | 2.4 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.4 | 11.7 | GO:0016342 | catenin complex(GO:0016342) |
| 0.4 | 1.9 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.3 | 8.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.3 | 1.7 | GO:0071547 | piP-body(GO:0071547) |
| 0.3 | 12.7 | GO:0005921 | gap junction(GO:0005921) |
| 0.3 | 2.8 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 5.2 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.3 | 0.8 | GO:1990913 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 0.3 | 0.8 | GO:0060187 | cell pole(GO:0060187) |
| 0.3 | 18.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.2 | 3.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 4.7 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.2 | 3.7 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.2 | 8.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 0.7 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.2 | 5.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.2 | 11.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 10.1 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.2 | 1.1 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.2 | 2.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.2 | 0.9 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.2 | 2.1 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.2 | 10.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 1.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 4.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 4.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.2 | 25.6 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.2 | 59.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 1.5 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.2 | 0.6 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.2 | 1.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.2 | 0.9 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.2 | 38.3 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.2 | 2.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 2.6 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 2.4 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 0.8 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.2 | 3.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.2 | 17.0 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.2 | 0.8 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.2 | 0.5 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.2 | 2.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.2 | 2.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.2 | 3.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 40.4 | GO:0030426 | growth cone(GO:0030426) |
| 0.2 | 1.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.2 | 2.9 | GO:0097450 | astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451) |
| 0.2 | 1.7 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.6 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.6 | GO:0097636 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.1 | 1.9 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 5.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 1.4 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.1 | 86.9 | GO:0005874 | microtubule(GO:0005874) |
| 0.1 | 4.8 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.9 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 1.2 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 5.5 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 2.8 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 0.6 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.1 | 0.9 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 0.3 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.1 | 2.0 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 2.8 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.0 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 2.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 6.4 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 0.3 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.1 | 0.7 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 4.5 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 1.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 1.2 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.1 | 3.6 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 4.1 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 0.3 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.1 | 6.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 11.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 19.8 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 3.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.4 | GO:0035363 | histone locus body(GO:0035363) |
| 0.1 | 0.6 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.1 | 13.5 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 0.2 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.1 | 1.0 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.1 | 0.8 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 0.5 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 1.0 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.4 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.1 | 0.8 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 0.7 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 1.3 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.2 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.1 | 1.9 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 0.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 3.2 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.8 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 0.1 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 1.0 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 5.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 2.3 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 0.9 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 0.2 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 3.1 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 5.2 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 0.3 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.1 | 1.8 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.1 | 1.9 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.1 | 0.4 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 0.1 | GO:0034705 | potassium channel complex(GO:0034705) |
| 0.0 | 0.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 5.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.2 | GO:0035101 | FACT complex(GO:0035101) |
| 0.0 | 7.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 3.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.4 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.7 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 11.8 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 8.4 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 13.6 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.3 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.0 | 5.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.2 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.5 | GO:0044297 | cell body(GO:0044297) |
| 0.0 | 0.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 3.1 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.9 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 7.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 0.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.3 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.2 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 1.5 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 0.3 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 3.2 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 2.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 0.2 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.0 | 0.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 2.8 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 4.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.6 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.7 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 1.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.9 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.0 | 0.1 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.4 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 1.3 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 3.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.8 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 3.3 | GO:0043005 | neuron projection(GO:0043005) |
| 0.0 | 0.3 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.1 | GO:0038201 | TOR complex(GO:0038201) |
| 0.0 | 0.9 | GO:0005814 | centriole(GO:0005814) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 58.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 2.2 | 11.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 1.6 | 7.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 1.3 | 5.2 | GO:0004113 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113) |
| 1.3 | 5.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.1 | 3.2 | GO:0004336 | galactosylceramidase activity(GO:0004336) |
| 1.1 | 13.8 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 1.0 | 5.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 1.0 | 3.9 | GO:0072591 | citrate-L-glutamate ligase activity(GO:0072591) |
| 1.0 | 4.8 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.9 | 3.8 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.8 | 3.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.7 | 9.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.7 | 4.4 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.7 | 4.3 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.7 | 2.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.7 | 3.4 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.7 | 2.0 | GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842) |
| 0.6 | 8.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.6 | 3.1 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.6 | 1.8 | GO:0035473 | lipase binding(GO:0035473) |
| 0.6 | 3.0 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.6 | 1.7 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.6 | 5.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.6 | 8.0 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.6 | 18.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.6 | 2.8 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
| 0.5 | 10.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.5 | 2.6 | GO:0016213 | linoleoyl-CoA desaturase activity(GO:0016213) |
| 0.5 | 1.5 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.5 | 1.0 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.5 | 2.0 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 0.5 | 2.0 | GO:0008431 | vitamin E binding(GO:0008431) |
| 0.5 | 9.6 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.5 | 10.1 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.5 | 1.4 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.5 | 2.3 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.5 | 1.4 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.4 | 4.5 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.4 | 3.6 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.4 | 3.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.4 | 1.7 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.4 | 4.1 | GO:1903763 | gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.4 | 1.6 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.4 | 2.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.4 | 2.4 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.4 | 3.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.4 | 1.1 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.4 | 11.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.4 | 1.9 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.4 | 7.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.4 | 3.7 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.4 | 1.1 | GO:0043849 | Ras palmitoyltransferase activity(GO:0043849) |
| 0.4 | 5.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 7.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.3 | 1.7 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.3 | 16.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.3 | 1.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.3 | 3.1 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.3 | 1.8 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.3 | 6.6 | GO:0019841 | retinol binding(GO:0019841) |
| 0.3 | 3.8 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.3 | 3.7 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.3 | 1.1 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.3 | 4.7 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.3 | 4.1 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.3 | 2.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.3 | 2.7 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.3 | 4.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.3 | 0.8 | GO:0002135 | CTP binding(GO:0002135) |
| 0.3 | 3.9 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.3 | 5.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.3 | 1.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.3 | 1.0 | GO:0033265 | choline binding(GO:0033265) |
| 0.2 | 0.7 | GO:0030943 | mitochondrion targeting sequence binding(GO:0030943) |
| 0.2 | 0.7 | GO:0015203 | polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489) |
| 0.2 | 0.5 | GO:0030614 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 0.2 | 0.7 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.2 | 9.6 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.2 | 1.2 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.2 | 0.9 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.2 | 1.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 1.1 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.2 | 2.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.2 | 12.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 2.1 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.2 | 0.8 | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity(GO:0004419) |
| 0.2 | 4.8 | GO:0005522 | profilin binding(GO:0005522) |
| 0.2 | 5.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 1.7 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.2 | 0.8 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.2 | 1.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 2.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.2 | 1.6 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.2 | 2.6 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.2 | 1.8 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 5.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 1.7 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.2 | 1.3 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 1.0 | GO:0045485 | omega-6 fatty acid desaturase activity(GO:0045485) |
| 0.2 | 5.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.2 | 5.1 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 1.1 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.2 | 2.0 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.2 | 3.8 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
| 0.2 | 3.4 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.2 | 1.8 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 2.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 7.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 14.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.2 | 3.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 1.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 2.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.2 | 2.6 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.2 | 6.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.2 | 4.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 1.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.2 | 0.7 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.2 | 1.3 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.2 | 0.8 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.2 | 0.7 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.2 | 0.7 | GO:0003947 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947) |
| 0.2 | 1.3 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.2 | 0.9 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 4.0 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.2 | 88.1 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.2 | 1.8 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 17.0 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.2 | 3.1 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.2 | 1.7 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 12.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 1.3 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.1 | 0.6 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.6 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.1 | 6.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 3.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 2.6 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 1.0 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 1.4 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.1 | 2.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 8.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 1.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 0.8 | GO:0052840 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 3.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 4.2 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 0.5 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.1 | 0.5 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 6.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.5 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.1 | 1.4 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.1 | 0.6 | GO:0097001 | glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001) |
| 0.1 | 2.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 1.4 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 4.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.3 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.1 | 0.9 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.1 | 8.4 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 1.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 1.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.1 | 0.6 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 2.1 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 0.5 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
| 0.1 | 0.6 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.1 | 0.8 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.1 | 0.7 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 0.8 | GO:0008174 | mRNA methyltransferase activity(GO:0008174) |
| 0.1 | 2.0 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.1 | 1.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 5.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 2.7 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.1 | 8.7 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.1 | 0.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 0.4 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 1.9 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 2.2 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 23.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.5 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.1 | 2.6 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 5.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 1.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 2.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 0.5 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 3.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.3 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.1 | 5.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 1.3 | GO:0036122 | BMP binding(GO:0036122) |
| 0.1 | 10.5 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.1 | 0.4 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588) |
| 0.1 | 0.9 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 0.5 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.1 | 0.8 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.1 | 1.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.1 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.1 | 3.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 0.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 1.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.1 | 1.0 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.1 | 1.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.7 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 0.8 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.7 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 2.8 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 0.8 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 1.6 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.8 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 1.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 1.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 1.7 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135) |
| 0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 2.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.7 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 0.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 1.3 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.1 | 18.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 1.2 | GO:0042910 | xenobiotic transporter activity(GO:0042910) |
| 0.1 | 0.7 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.1 | 2.7 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 0.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 3.7 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.1 | 0.3 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 0.2 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.1 | 1.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 14.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 1.9 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 0.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 2.3 | GO:0060590 | ATPase regulator activity(GO:0060590) |
| 0.1 | 0.4 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 0.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 0.4 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 2.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.1 | 0.6 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 1.2 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 2.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.2 | GO:0004488 | formate-tetrahydrofolate ligase activity(GO:0004329) methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 0.1 | 1.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 2.4 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 0.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 0.7 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 1.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 55.4 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 1.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.1 | 0.2 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.1 | 0.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.0 | 0.1 | GO:0097603 | temperature-gated ion channel activity(GO:0097603) temperature-gated cation channel activity(GO:0097604) |
| 0.0 | 0.2 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.0 | 2.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.4 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 0.4 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 1.4 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.8 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 1.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 0.0 | 1.4 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 1.8 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.2 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.0 | 2.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 5.3 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 1.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 1.1 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 1.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 1.5 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.2 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.4 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.0 | 1.0 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.0 | 0.1 | GO:0048040 | UDP-glucuronate decarboxylase activity(GO:0048040) |
| 0.0 | 2.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.2 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.0 | 0.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 5.1 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.5 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 0.7 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 0.0 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.9 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.0 | 1.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.2 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.0 | 0.2 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 5.0 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 1.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.1 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 0.5 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.0 | 0.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 0.2 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 0.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.1 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.3 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 0.0 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 0.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.2 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 44.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.6 | 1.9 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.3 | 12.6 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 8.7 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.2 | 8.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.2 | 0.6 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.2 | 17.6 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.2 | 18.3 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 3.9 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 0.9 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.1 | 9.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 8.0 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 6.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 6.2 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 12.0 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 6.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 6.8 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 8.6 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.1 | 5.6 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 2.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 4.3 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.1 | 2.9 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 1.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 1.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 2.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 1.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 3.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 2.5 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 2.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 4.4 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 3.5 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.5 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 1.8 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.7 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.1 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 1.5 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 2.3 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 2.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.1 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.9 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.7 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.3 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.8 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 1.0 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.4 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.3 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.2 | PID ALK1 PATHWAY | ALK1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 30.7 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.8 | 30.1 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.4 | 7.0 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.4 | 7.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.3 | 10.0 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.3 | 0.8 | REACTOME MRNA CAPPING | Genes involved in mRNA Capping |
| 0.2 | 1.2 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.2 | 8.2 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.2 | 1.6 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 5.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.2 | 13.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 3.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.2 | 7.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.2 | 8.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 1.1 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.2 | 10.5 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 4.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.2 | 8.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.2 | 7.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 2.9 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 3.1 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 4.1 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.1 | 1.0 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.1 | 8.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.8 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.1 | 2.8 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.1 | 2.1 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.1 | 4.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 7.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.0 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 3.6 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 2.8 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 8.4 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 3.0 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 2.0 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 4.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 4.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 7.0 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 2.9 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 2.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 6.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 2.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.1 | 2.1 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 2.3 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 1.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 0.9 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 3.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.4 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 8.6 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 1.8 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 0.7 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 3.0 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 0.2 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 0.5 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.1 | 1.0 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 2.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 2.6 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.9 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 4.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.3 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.0 | 5.9 | REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.0 | 1.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.5 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.4 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.5 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 0.3 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 3.1 | REACTOME SIGNALING BY FGFR | Genes involved in Signaling by FGFR |
| 0.0 | 0.7 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 1.1 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.8 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 1.0 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.0 | 0.5 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 1.2 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.2 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.2 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.0 | 0.6 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.0 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 1.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 1.0 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.0 | 0.4 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.2 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.0 | 0.2 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.3 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.2 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |