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avrg: Illumina Body Map 2 (GSE30611)

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Results for SPDEF

Z-value: 1.76

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Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
SPDEF
ENSG00000124664.11 SPDEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg38_v1_chr6_-_34556319_34556339-0.076.9e-01Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_122716790 4.80 ENST00000528880.3
HCAR3
hydroxycarboxylic acid receptor 3
chr1_+_151156627 3.96 ENST00000368910.4
TNFAIP8L2
TNF alpha induced protein 8 like 2
chr6_-_41286665 3.92 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
TREM1
triggering receptor expressed on myeloid cells 1
chrX_+_124346544 3.80 ENST00000371139.9
SH2D1A
SH2 domain containing 1A
chr12_-_122703346 3.79 ENST00000328880.6
HCAR2
hydroxycarboxylic acid receptor 2
chr14_+_22462932 3.78 ENST00000390477.2
TRDC
T cell receptor delta constant
chr6_-_31592952 3.47 ENST00000376073.8
ENST00000376072.7
NCR3
natural cytotoxicity triggering receptor 3
chrX_+_118495803 3.17 ENST00000276202.9
ENST00000276204.10
DOCK11
dedicator of cytokinesis 11
chr1_+_24502830 3.05 ENST00000374395.9
RCAN3
RCAN family member 3
chr16_+_77190835 3.03 ENST00000569610.5
ENST00000567291.5
ENST00000563612.1
ENST00000563279.5
MON1B
MON1 homolog B, secretory trafficking associated
chr16_+_77191173 2.88 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1B
MON1 homolog B, secretory trafficking associated
chr1_+_84164962 2.86 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr8_-_130016536 2.76 ENST00000519020.5
CYRIB
CYFIP related Rac1 interactor B
chrX_-_154547546 2.76 ENST00000440967.5
ENST00000369620.6
ENST00000393564.6
G6PD
glucose-6-phosphate dehydrogenase
chr8_-_130016414 2.76 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYRIB
CYFIP related Rac1 interactor B
chr15_-_64356074 2.75 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
CSNK1G1
casein kinase 1 gamma 1
chr1_+_24502894 2.75 ENST00000436717.6
ENST00000616511.4
RCAN3
RCAN family member 3
chr6_-_31592992 2.73 ENST00000340027.10
NCR3
natural cytotoxicity triggering receptor 3
chr8_-_129939694 2.70 ENST00000522250.5
ENST00000522941.5
ENST00000522746.5
ENST00000520204.5
ENST00000519070.5
ENST00000520254.5
ENST00000519824.6
CYRIB
CYFIP related Rac1 interactor B
chr8_-_130016395 2.66 ENST00000523509.5
CYRIB
CYFIP related Rac1 interactor B
chr8_-_100952604 2.61 ENST00000523131.1
ENST00000418997.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr8_-_130016622 2.58 ENST00000518283.5
ENST00000519110.5
CYRIB
CYFIP related Rac1 interactor B
chr11_-_118252279 2.55 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
MPZL3
myelin protein zero like 3
chr8_-_129939872 2.53 ENST00000519540.5
CYRIB
CYFIP related Rac1 interactor B
chrX_+_124346525 2.50 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr8_-_100952876 2.43 ENST00000437293.5
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr19_+_40576849 2.40 ENST00000600733.5
ENST00000291842.10
ENST00000600718.5
SHKBP1
SH3KBP1 binding protein 1
chr11_-_61361834 2.31 ENST00000544118.5
ENST00000294072.9
ENST00000545361.5
ENST00000539128.5
ENST00000546151.5
ENST00000447532.6
CYB561A3
cytochrome b561 family member A3
chr1_+_84164891 2.30 ENST00000413538.5
ENST00000417530.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr11_-_61362246 2.29 ENST00000537680.5
ENST00000426130.6
CYB561A3
cytochrome b561 family member A3
chr1_+_84164370 2.18 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr1_-_65067707 2.14 ENST00000672099.1
ENST00000671954.1
ENST00000672434.1
ENST00000673502.1
ENST00000672751.1
JAK1
Janus kinase 1
chr8_-_100952918 2.13 ENST00000395957.6
ENST00000395948.6
ENST00000457309.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr2_+_71068278 2.03 ENST00000613852.4
ENST00000455662.6
ENST00000531934.5
NAGK
N-acetylglucosamine kinase
chr2_+_101002229 2.02 ENST00000409000.5
ENST00000409028.8
ENST00000264258.8
ENST00000409320.7
ENST00000409733.5
ENST00000409650.5
ENST00000409038.5
RPL31
ribosomal protein L31
chr2_+_65227792 1.99 ENST00000260641.10
ENST00000377982.8
ACTR2
actin related protein 2
chr7_+_100148890 1.96 ENST00000341942.9
ENST00000474141.5
ENST00000460732.5
ENST00000441173.1
ENST00000468582.5
ENST00000488241.5
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_7637099 1.96 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
STXBP2
syntaxin binding protein 2
chr1_-_19485502 1.91 ENST00000264203.7
ENST00000375144.6
ENST00000674432.1
ENST00000264202.8
CAPZB
capping actin protein of muscle Z-line subunit beta
chr1_+_84164293 1.90 ENST00000370684.5
ENST00000436133.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_+_29149238 1.87 ENST00000536681.8
FAR2
fatty acyl-CoA reductase 2
chr3_+_31981740 1.87 ENST00000360311.5
ZNF860
zinc finger protein 860
chr2_+_101002496 1.80 ENST00000456292.5
ENST00000409711.1
ENST00000441435.1
RPL31
ribosomal protein L31
chr11_-_46121397 1.80 ENST00000676320.1
PHF21A
PHD finger protein 21A
chr14_-_77616630 1.77 ENST00000216484.7
SPTLC2
serine palmitoyltransferase long chain base subunit 2
chr8_-_56074144 1.72 ENST00000618656.2
RPS20
ribosomal protein S20
chr2_+_71068636 1.72 ENST00000244204.11
ENST00000533981.5
NAGK
N-acetylglucosamine kinase
chr8_-_56074312 1.71 ENST00000523936.5
RPS20
ribosomal protein S20
chr8_-_100952507 1.69 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chrX_+_124346571 1.67 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr2_+_71068603 1.67 ENST00000443938.6
NAGK
N-acetylglucosamine kinase
chr1_+_66930239 1.63 ENST00000401042.7
ENST00000355356.3
MIER1
MIER1 transcriptional regulator
chr7_+_114922346 1.61 ENST00000393486.5
MDFIC
MyoD family inhibitor domain containing
chr20_-_63568074 1.59 ENST00000427522.6
HELZ2
helicase with zinc finger 2
chr8_-_56074492 1.59 ENST00000518875.5
ENST00000524349.5
ENST00000009589.8
ENST00000519606.5
ENST00000519807.5
ENST00000520627.1
ENST00000521262.5
RPS20
ribosomal protein S20
chr8_+_99013247 1.57 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
VPS13B
vacuolar protein sorting 13 homolog B
chr15_-_64356047 1.56 ENST00000634654.1
CSNK1G1
casein kinase 1 gamma 1
chr20_+_62387086 1.51 ENST00000343986.9
RPS21
ribosomal protein S21
chr17_-_37609361 1.48 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
SYNRG
synergin gamma
chr1_+_52602347 1.47 ENST00000361314.5
GPX7
glutathione peroxidase 7
chr2_+_161160299 1.46 ENST00000440506.5
ENST00000429217.5
ENST00000406287.5
ENST00000402568.5
TANK
TRAF family member associated NFKB activator
chr19_-_1174227 1.41 ENST00000587024.5
ENST00000361757.8
SBNO2
strawberry notch homolog 2
chr17_-_18314956 1.39 ENST00000321105.10
ENST00000542570.5
TOP3A
DNA topoisomerase III alpha
chr1_-_153922742 1.37 ENST00000634408.1
ENST00000634791.1
GATAD2B
GATA zinc finger domain containing 2B
chr17_-_49788554 1.36 ENST00000513602.5
FAM117A
family with sequence similarity 117 member A
chr7_-_77798359 1.35 ENST00000257663.4
TMEM60
transmembrane protein 60
chr12_+_27243968 1.33 ENST00000541191.5
STK38L
serine/threonine kinase 38 like
chr17_-_7205116 1.31 ENST00000649520.1
ENST00000649186.1
DLG4
discs large MAGUK scaffold protein 4
chr19_+_40577158 1.30 ENST00000595631.5
SHKBP1
SH3KBP1 binding protein 1
chr8_-_116755784 1.30 ENST00000518949.5
ENST00000522453.1
ENST00000518995.5
ENST00000521861.6
ENST00000611080.1
EIF3H
eukaryotic translation initiation factor 3 subunit H
chr22_-_21982748 1.28 ENST00000398793.6
ENST00000437929.5
ENST00000456075.5
ENST00000434517.1
ENST00000424393.5
ENST00000357179.10
ENST00000449704.5
ENST00000437103.1
TOP3B
DNA topoisomerase III beta
chr1_+_109548567 1.28 ENST00000369851.7
GNAI3
G protein subunit alpha i3
chr15_-_64989894 1.27 ENST00000416889.6
ENST00000204566.7
SPG21
SPG21 abhydrolase domain containing, maspardin
chrX_+_49235460 1.27 ENST00000376227.4
CCDC22
coiled-coil domain containing 22
chr1_+_42658335 1.27 ENST00000677900.1
ENST00000372550.6
ENST00000676675.1
ENST00000304979.8
ENST00000678803.1
ENST00000678333.1
ENST00000440068.6
PPIH
peptidylprolyl isomerase H
chr1_+_84164684 1.27 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr19_+_19385815 1.26 ENST00000494516.6
ENST00000360315.7
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_21279520 1.25 ENST00000357071.8
ECE1
endothelin converting enzyme 1
chr1_-_19485468 1.24 ENST00000375142.5
CAPZB
capping actin protein of muscle Z-line subunit beta
chr16_+_70523782 1.24 ENST00000566095.6
ENST00000577085.1
ENST00000302516.10
ENST00000567654.1
SF3B3
splicing factor 3b subunit 3
chr7_-_38909174 1.21 ENST00000395969.6
ENST00000310301.9
ENST00000414632.5
VPS41
VPS41 subunit of HOPS complex
chr10_-_14954018 1.20 ENST00000378241.5
ENST00000456122.1
ENST00000418843.5
ENST00000378249.5
ENST00000396817.6
ENST00000378255.5
ENST00000378254.5
ENST00000357717.6
ENST00000378258.5
ENST00000378246.6
ENST00000378278.7
DCLRE1C
DNA cross-link repair 1C
chr1_+_84164669 1.20 ENST00000450730.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_+_161160420 1.19 ENST00000392749.7
ENST00000405852.5
TANK
TRAF family member associated NFKB activator
chr19_+_19385919 1.19 ENST00000417582.6
GATAD2A
GATA zinc finger domain containing 2A
chr15_-_55408245 1.19 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
CCPG1
cell cycle progression 1
chr10_-_124744254 1.18 ENST00000280780.6
FAM53B
family with sequence similarity 53 member B
chr10_-_124744280 1.18 ENST00000337318.8
FAM53B
family with sequence similarity 53 member B
chr1_+_193060034 1.18 ENST00000367446.7
ENST00000367443.5
ENST00000367444.7
ENST00000367445.7
RO60
Ro60, Y RNA binding protein
chr17_+_7573722 1.16 ENST00000581384.5
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr11_+_61362355 1.15 ENST00000542946.1
ENST00000278826.11
TMEM138
transmembrane protein 138
chr11_+_66268575 1.15 ENST00000527397.1
ENST00000311481.11
RAB1B
RAB1B, member RAS oncogene family
chr16_+_2537997 1.15 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
PDPK1
3-phosphoinositide dependent protein kinase 1
chr4_+_152779934 1.13 ENST00000451320.6
ENST00000429148.6
ENST00000353617.7
ENST00000405727.6
ENST00000356064.3
ARFIP1
ADP ribosylation factor interacting protein 1
chr17_-_78840647 1.11 ENST00000587783.5
ENST00000542802.7
ENST00000586531.5
ENST00000589424.5
ENST00000590546.6
USP36
ubiquitin specific peptidase 36
chr14_-_31457417 1.11 ENST00000356180.4
DTD2
D-aminoacyl-tRNA deacylase 2
chr22_-_21982807 1.10 ENST00000430142.5
TOP3B
DNA topoisomerase III beta
chr3_-_31981228 1.09 ENST00000396556.7
ENST00000438237.6
OSBPL10
oxysterol binding protein like 10
chr17_-_8162932 1.09 ENST00000488857.5
ENST00000316509.11
ENST00000481878.1
ENST00000498285.1
VAMP2
ENSG00000263620.1
vesicle associated membrane protein 2
novel protein
chr22_+_21665994 1.08 ENST00000680393.1
ENST00000679534.1
ENST00000679827.1
ENST00000681956.1
ENST00000681338.1
ENST00000680061.1
ENST00000679540.1
ENST00000679795.1
ENST00000335025.12
ENST00000398831.8
ENST00000679477.1
ENST00000626352.2
ENST00000458567.5
ENST00000680094.1
ENST00000680109.1
ENST00000406385.1
ENST00000680860.1
PPIL2
peptidylprolyl isomerase like 2
chr6_-_42746054 1.07 ENST00000372876.2
TBCC
tubulin folding cofactor C
chr2_-_38875872 1.06 ENST00000457308.6
ENST00000619207.1
DHX57
DExH-box helicase 57
chr19_+_36687579 1.06 ENST00000682579.1
ENST00000536254.6
ZNF567
zinc finger protein 567
chr12_+_131949893 1.06 ENST00000389561.7
ENST00000332482.8
ENST00000333577.8
EP400
E1A binding protein p400
chr11_+_44565591 1.06 ENST00000342935.7
CD82
CD82 molecule
chr14_-_24242600 1.03 ENST00000646753.1
ENST00000558566.1
ENST00000267415.12
ENST00000559019.1
ENST00000399423.8
ENST00000626689.2
TINF2
TERF1 interacting nuclear factor 2
chr15_-_55408467 0.99 ENST00000310958.10
CCPG1
cell cycle progression 1
chrX_-_123733023 0.97 ENST00000245838.13
ENST00000355725.8
THOC2
THO complex 2
chr12_-_56725322 0.97 ENST00000679092.1
NACA
nascent polypeptide associated complex subunit alpha
chr14_-_24242567 0.96 ENST00000558476.5
TINF2
TERF1 interacting nuclear factor 2
chr17_-_8383164 0.96 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
RPL26
ribosomal protein L26
chr17_+_18315273 0.95 ENST00000406438.5
SMCR8
SMCR8-C9orf72 complex subunit
chr11_-_72041054 0.95 ENST00000542977.5
NUMA1
nuclear mitotic apparatus protein 1
chr15_-_55408018 0.94 ENST00000569205.5
CCPG1
cell cycle progression 1
chr1_+_193059587 0.93 ENST00000400968.7
ENST00000415442.2
ENST00000506303.1
RO60
Ro60, Y RNA binding protein
chr1_-_153922901 0.93 ENST00000634401.1
ENST00000368655.5
GATAD2B
GATA zinc finger domain containing 2B
chr2_+_65228122 0.91 ENST00000542850.2
ACTR2
actin related protein 2
chr8_+_9002844 0.88 ENST00000519292.5
ENST00000250263.8
ERI1
exoribonuclease 1
chr14_-_24242320 0.88 ENST00000557921.2
TINF2
TERF1 interacting nuclear factor 2
chr19_+_18571730 0.87 ENST00000596304.5
ENST00000430157.6
ENST00000596273.5
ENST00000442744.7
ENST00000595683.5
ENST00000599256.5
ENST00000595158.5
ENST00000598780.5
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr3_+_196942638 0.87 ENST00000602845.2
NCBP2AS2
NCBP2 antisense 2 (head to head)
chr15_+_40894410 0.86 ENST00000220509.10
ENST00000558474.1
VPS18
VPS18 core subunit of CORVET and HOPS complexes
chr8_-_66667138 0.84 ENST00000310421.5
VCPIP1
valosin containing protein interacting protein 1
chr7_+_93921720 0.84 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr14_-_21269451 0.83 ENST00000336053.10
HNRNPC
heterogeneous nuclear ribonucleoprotein C
chr1_-_184754808 0.83 ENST00000318130.13
ENST00000367512.7
EDEM3
ER degradation enhancing alpha-mannosidase like protein 3
chr1_+_193059448 0.82 ENST00000432079.5
RO60
Ro60, Y RNA binding protein
chr3_-_69052309 0.82 ENST00000398559.7
ENST00000646708.1
ENST00000646304.1
TMF1
TATA element modulatory factor 1
chr6_-_43516883 0.81 ENST00000372422.7
ENST00000506469.5
ENST00000503972.5
YIPF3
Yip1 domain family member 3
chrX_-_48957871 0.80 ENST00000610466.4
OTUD5
OTU deubiquitinase 5
chr14_-_21269392 0.79 ENST00000554891.5
ENST00000555883.5
ENST00000553753.5
ENST00000555914.5
ENST00000557336.1
ENST00000555215.5
ENST00000556628.5
ENST00000555137.5
ENST00000556226.5
ENST00000555309.5
ENST00000556142.5
ENST00000554969.5
ENST00000554455.5
ENST00000556513.5
ENST00000557201.5
ENST00000420743.6
ENST00000557768.1
ENST00000553300.6
ENST00000554383.5
ENST00000554539.5
HNRNPC
heterogeneous nuclear ribonucleoprotein C
chr17_-_49677976 0.78 ENST00000665825.1
ENST00000508805.5
ENST00000515508.6
ENST00000451526.6
ENST00000507970.5
SPOP
speckle type BTB/POZ protein
chr19_+_58387260 0.77 ENST00000598098.5
ENST00000598495.5
ENST00000196551.8
ENST00000596046.1
RPS5
ribosomal protein S5
chr12_-_56725256 0.77 ENST00000552540.5
ENST00000678047.1
ENST00000393891.8
ENST00000678416.1
ENST00000678066.1
NACA
nascent polypeptide associated complex subunit alpha
chr19_+_45178739 0.77 ENST00000433642.3
BLOC1S3
biogenesis of lysosomal organelles complex 1 subunit 3
chr2_+_48440757 0.77 ENST00000294952.13
ENST00000281394.8
ENST00000449090.6
PPP1R21
protein phosphatase 1 regulatory subunit 21
chr20_-_35664837 0.75 ENST00000414711.5
ENST00000416778.5
ENST00000397442.5
ENST00000440240.5
ENST00000412056.5
ENST00000352393.8
ENST00000458038.5
ENST00000397443.7
ENST00000420363.5
ENST00000434795.5
ENST00000437100.5
ENST00000414664.5
ENST00000359646.1
ENST00000424458.5
ENST00000374114.8
ENST00000374104.7
CPNE1
RBM12
copine 1
RNA binding motif protein 12
chr12_-_53079363 0.73 ENST00000547837.5
ENST00000301463.9
SPRYD3
SPRY domain containing 3
chr7_+_100676112 0.73 ENST00000412215.5
ENST00000393924.1
GNB2
G protein subunit beta 2
chr10_-_118046574 0.72 ENST00000369199.5
RAB11FIP2
RAB11 family interacting protein 2
chr17_-_78840881 0.72 ENST00000312010.10
USP36
ubiquitin specific peptidase 36
chr2_-_37084302 0.71 ENST00000233099.6
HEATR5B
HEAT repeat containing 5B
chr17_-_64662290 0.71 ENST00000262435.14
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr16_+_4616475 0.70 ENST00000591895.5
MGRN1
mahogunin ring finger 1
chr3_-_133661896 0.69 ENST00000260810.10
TOPBP1
DNA topoisomerase II binding protein 1
chrX_-_48957548 0.69 ENST00000376488.8
ENST00000396743.7
ENST00000156084.8
OTUD5
OTU deubiquitinase 5
chr12_+_27244222 0.69 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
STK38L
serine/threonine kinase 38 like
chr2_+_216498831 0.68 ENST00000491306.6
ENST00000600880.5
ENST00000446558.5
RPL37A
ribosomal protein L37a
chr19_-_1650667 0.67 ENST00000587235.6
TCF3
transcription factor 3
chr20_-_35664925 0.67 ENST00000430570.5
ENST00000439806.6
ENST00000437340.5
ENST00000435161.1
ENST00000431148.1
CPNE1
RBM12
copine 1
RNA binding motif protein 12
chr12_-_56725284 0.65 ENST00000550920.6
ENST00000678376.1
ENST00000550952.6
ENST00000454682.6
ENST00000548563.5
ENST00000546862.6
NACA
nascent polypeptide associated complex subunit alpha
chr10_-_118046922 0.65 ENST00000355624.8
RAB11FIP2
RAB11 family interacting protein 2
chr14_+_24232422 0.65 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
GMPR2
guanosine monophosphate reductase 2
chr2_-_128027273 0.65 ENST00000259235.7
ENST00000357702.9
ENST00000424298.5
SAP130
Sin3A associated protein 130
chr12_-_49568099 0.65 ENST00000553173.5
ENST00000550165.5
ENST00000343810.9
ENST00000546244.5
MCRS1
microspherule protein 1
chr6_+_30557274 0.65 ENST00000376557.3
PRR3
proline rich 3
chr19_-_44500503 0.64 ENST00000587047.1
ENST00000391956.8
ENST00000221327.8
ENST00000592529.6
ENST00000591064.1
ZNF180
zinc finger protein 180
chr15_-_43371017 0.63 ENST00000684362.1
ZSCAN29
zinc finger and SCAN domain containing 29
chr14_-_24146596 0.62 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
PSME2
proteasome activator subunit 2
chrX_+_154547606 0.62 ENST00000594239.6
ENST00000615874.4
ENST00000619941.4
ENST00000617207.4
ENST00000611176.4
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr8_+_22605018 0.62 ENST00000389279.7
CCAR2
cell cycle and apoptosis regulator 2
chr1_-_19799872 0.61 ENST00000294543.11
TMCO4
transmembrane and coiled-coil domains 4
chr11_+_65615755 0.61 ENST00000355703.4
PCNX3
pecanex 3
chr7_-_6059139 0.60 ENST00000446699.1
ENST00000199389.11
EIF2AK1
eukaryotic translation initiation factor 2 alpha kinase 1
chr14_+_24232612 0.60 ENST00000560139.5
ENST00000559910.5
ENST00000348719.11
GMPR2
guanosine monophosphate reductase 2
chr17_-_49678074 0.59 ENST00000505581.5
ENST00000504102.6
ENST00000514121.6
ENST00000393328.6
ENST00000509079.6
ENST00000347630.6
SPOP
speckle type BTB/POZ protein
chr2_-_218671975 0.59 ENST00000295704.7
RNF25
ring finger protein 25
chr1_-_42335189 0.59 ENST00000361776.5
ENST00000445886.5
ENST00000361346.6
FOXJ3
forkhead box J3
chr5_+_159263282 0.58 ENST00000296786.8
UBLCP1
ubiquitin like domain containing CTD phosphatase 1
chr11_-_72040694 0.57 ENST00000535947.5
NUMA1
nuclear mitotic apparatus protein 1
chr3_-_196942427 0.57 ENST00000411704.1
ENST00000452404.6
NCBP2
nuclear cap binding protein subunit 2
chr10_-_98446878 0.56 ENST00000338546.9
ENST00000325103.10
ENST00000361490.9
HPS1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1
chr2_+_37084486 0.56 ENST00000281932.6
ENST00000674370.2
GPATCH11
G-patch domain containing 11
chr14_-_24146314 0.56 ENST00000559056.5
PSME2
proteasome activator subunit 2
chr3_-_196942377 0.55 ENST00000447325.5
NCBP2
nuclear cap binding protein subunit 2
chr19_+_4007714 0.54 ENST00000262971.3
PIAS4
protein inhibitor of activated STAT 4
chr6_+_30557287 0.54 ENST00000376560.8
PRR3
proline rich 3
chr9_-_113221288 0.53 ENST00000446284.6
ENST00000414250.2
FKBP15
FKBP prolyl isomerase family member 15
chr12_+_118376539 0.52 ENST00000543473.2
SUDS3
SDS3 homolog, SIN3A corepressor complex component
chr3_+_94062974 0.52 ENST00000314622.9
NSUN3
NOP2/Sun RNA methyltransferase 3
chr2_+_27583015 0.52 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
ZNF512
ENSG00000259080.1
zinc finger protein 512
novel transcript
chr15_-_74461102 0.51 ENST00000567435.5
ENST00000564488.5
ENST00000565130.5
ENST00000563081.1
ENST00000565335.5
ENST00000395081.7
ENST00000361351.8
UBL7
ubiquitin like 7
chr9_-_129824236 0.51 ENST00000651202.1
TOR1A
torsin family 1 member A
chr17_+_43483949 0.50 ENST00000540306.5
ENST00000262415.8
DHX8
DEAH-box helicase 8
chr8_+_22604632 0.50 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
CCAR2
cell cycle and apoptosis regulator 2
chr2_-_27071628 0.50 ENST00000447619.5
ENST00000429985.1
ENST00000456793.2
OST4
oligosaccharyltransferase complex subunit 4, non-catalytic
chr14_-_63543288 0.50 ENST00000555899.1
PPP2R5E
protein phosphatase 2 regulatory subunit B'epsilon
chr1_+_151070740 0.50 ENST00000368918.8
GABPB2
GA binding protein transcription factor subunit beta 2
chr5_+_87268922 0.49 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RASA1
RAS p21 protein activator 1
chr2_+_37084440 0.49 ENST00000409774.6
GPATCH11
G-patch domain containing 11
chr4_-_158671843 0.48 ENST00000379205.5
ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chrX_-_136880754 0.47 ENST00000565438.1
RBMX
RNA binding motif protein X-linked
chr17_-_7931910 0.47 ENST00000303731.9
ENST00000571947.5
ENST00000540486.5
ENST00000572656.2
TRAPPC1
trafficking protein particle complex 1
chr3_-_196942500 0.47 ENST00000321256.10
ENST00000427641.2
NCBP2
nuclear cap binding protein subunit 2
chr14_-_21383989 0.46 ENST00000216297.7
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit
chr3_-_139389604 0.46 ENST00000515006.5
ENST00000510181.6
ENST00000333188.10
ENST00000513274.5
ENST00000514508.2
ENST00000503326.6
ENST00000507777.6
ENST00000512242.6
ENST00000512153.5
ENST00000512309.2
COPB2
COPI coat complex subunit beta 2
chr10_-_119080794 0.46 ENST00000369144.8
ENST00000541549.2
EIF3A
eukaryotic translation initiation factor 3 subunit A
chr9_-_34126661 0.46 ENST00000361264.9
DCAF12
DDB1 and CUL4 associated factor 12
chr2_+_216499068 0.46 ENST00000456586.5
ENST00000427280.6
ENST00000598925.5
ENST00000441179.2
RPL37A
ribosomal protein L37a
chr12_-_102120065 0.46 ENST00000552283.6
ENST00000551744.2
NUP37
nucleoporin 37

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0019085 early viral transcription(GO:0019085)
1.2 11.7 GO:0097338 response to clozapine(GO:0097338)
1.0 6.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.9 5.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.8 3.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.6 9.7 GO:0090168 Golgi reassembly(GO:0090168)
0.6 1.8 GO:0006667 sphinganine metabolic process(GO:0006667)
0.6 3.9 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.5 2.8 GO:0009051 NADPH regeneration(GO:0006740) pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 2.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 1.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.4 1.6 GO:0006408 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.4 3.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.4 2.9 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.4 2.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.4 1.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.3 8.0 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.3 2.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3 3.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 2.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 3.8 GO:0006265 DNA topological change(GO:0006265)
0.2 0.8 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2 0.8 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.2 2.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.2 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 1.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.5 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 1.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.5 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2 3.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.4 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.6 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.7 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.9 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.5 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.1 2.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 5.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.6 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.7 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262) cell proliferation involved in heart valve development(GO:2000793)
0.1 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.7 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.4 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 1.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 10.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 1.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.2 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 1.7 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.8 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 3.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 3.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.0 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 2.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 1.4 GO:0003091 renal water homeostasis(GO:0003091)
0.0 2.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 2.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 1.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.4 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 1.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.6 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.4 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 1.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 2.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 4.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 2.5 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 1.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.2 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 1.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 2.5 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 4.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.9 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 1.5 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.5 2.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 11.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 1.1 GO:0044609 DBIRD complex(GO:0044609)
0.3 1.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.2 GO:0008537 proteasome activator complex(GO:0008537)
0.3 1.7 GO:1902560 GMP reductase complex(GO:1902560)
0.3 2.1 GO:0033263 CORVET complex(GO:0033263)
0.2 1.6 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 1.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 3.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 2.0 GO:0044194 cytolytic granule(GO:0044194)
0.2 2.9 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 1.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 1.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.2 2.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.5 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.5 GO:0035101 FACT complex(GO:0035101)
0.1 0.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 1.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.4 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 6.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 3.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 6.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.2 GO:0097346 INO80-type complex(GO:0097346)
0.0 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.0 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.8 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 7.2 GO:0072562 blood microparticle(GO:0072562)
0.0 2.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 5.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 4.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.7 2.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.6 5.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 3.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.5 11.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 2.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 2.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 1.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.3 0.9 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 1.7 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 1.5 GO:0004096 catalase activity(GO:0004096)
0.2 2.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 1.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 1.6 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 1.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.1 GO:1990405 protein antigen binding(GO:1990405)
0.1 1.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 13.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 7.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 4.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 8.9 GO:0044325 ion channel binding(GO:0044325)
0.0 3.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.3 GO:0017046 peptide hormone binding(GO:0017046)
0.0 6.3 GO:0051015 actin filament binding(GO:0051015)
0.0 3.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 3.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 2.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.6 PID IL3 PATHWAY IL3-mediated signaling events
0.2 2.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 2.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 4.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 4.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 8.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 20.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 2.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 8.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 7.1 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 2.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 8.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 5.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis