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avrg: Illumina Body Map 2 (GSE30611)

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Results for TCF7L1

Z-value: 1.84

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
ENSG00000152284.5 TCF7L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg38_v1_chr2_+_85133376_85133474-0.038.9e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_106975452 4.89 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr6_-_106975309 4.57 ENST00000615659.1
CD24 molecule
chr7_+_116210501 4.22 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr15_+_40844018 3.77 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr21_-_44910630 3.68 ENST00000320216.10
ENST00000397852.5
integrin subunit beta 2
chr1_-_153550083 3.65 ENST00000368714.1
S100 calcium binding protein A4
chr5_+_134114673 3.61 ENST00000342854.10
ENST00000395029.5
transcription factor 7
chr8_+_22161788 3.40 ENST00000521315.5
ENST00000437090.6
ENST00000679463.1
ENST00000520605.5
ENST00000522109.5
ENST00000524255.5
ENST00000523296.1
surfactant protein C
chr6_-_106974721 3.33 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr17_-_47957824 3.25 ENST00000300557.3
proline rich 15 like
chr4_+_77157189 3.18 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr17_-_40937445 3.14 ENST00000436344.7
ENST00000485751.1
keratin 23
chrX_-_154371210 3.02 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr17_-_40937641 2.96 ENST00000209718.8
keratin 23
chr21_+_29299368 2.95 ENST00000399921.5
BTB domain and CNC homolog 1
chr17_-_39864140 2.93 ENST00000623724.3
ENST00000439167.6
ENST00000377945.7
ENST00000394189.6
ENST00000377944.7
ENST00000377958.6
ENST00000535189.5
ENST00000377952.6
IKAROS family zinc finger 3
chr18_+_3450036 2.90 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr8_+_22161655 2.90 ENST00000318561.7
surfactant protein C
chr14_-_64942783 2.90 ENST00000612794.1
glutathione peroxidase 2
chr7_+_73830988 2.90 ENST00000340958.4
claudin 4
chr14_+_75279961 2.80 ENST00000557139.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr4_-_121072519 2.79 ENST00000379692.9
neuron derived neurotrophic factor
chr7_+_120989030 2.77 ENST00000428526.5
cadherin like and PC-esterase domain containing 1
chrX_+_72069659 2.71 ENST00000631375.1
NHS like 2
chr6_-_11778781 2.70 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr5_-_157575767 2.67 ENST00000257527.9
ADAM metallopeptidase domain 19
chr15_+_40844506 2.61 ENST00000568580.5
serine peptidase inhibitor, Kunitz type 1
chr14_+_75280078 2.54 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr17_+_77451244 2.53 ENST00000591088.5
septin 9
chr18_+_3449817 2.40 ENST00000407501.6
TGFB induced factor homeobox 1
chr12_-_31324129 2.40 ENST00000454658.6
SIN3-HDAC complex associated factor
chr7_+_80602200 2.38 ENST00000534394.5
CD36 molecule
chr9_-_35650902 2.37 ENST00000259608.8
ENST00000618781.1
signaling threshold regulating transmembrane adaptor 1
chr6_-_106975616 2.36 ENST00000610952.1
CD24 molecule
chr7_+_80602150 2.32 ENST00000309881.11
CD36 molecule
chr11_-_88175432 2.31 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr17_-_39864304 2.28 ENST00000346872.8
IKAROS family zinc finger 3
chr19_-_11339573 2.25 ENST00000222120.8
RAB3D, member RAS oncogene family
chr5_-_176537361 2.17 ENST00000274811.9
ring finger protein 44
chr17_-_39864126 2.14 ENST00000351680.7
ENST00000346243.7
ENST00000350532.7
ENST00000467757.5
ENST00000439016.2
IKAROS family zinc finger 3
chr5_-_139389905 2.09 ENST00000302125.9
marginal zone B and B1 cell specific protein
chr15_+_40844171 2.08 ENST00000563656.5
serine peptidase inhibitor, Kunitz type 1
chr8_-_33567118 2.07 ENST00000256257.2
ring finger protein 122
chr17_-_7394514 1.95 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chr5_-_157575741 1.94 ENST00000517905.1
ADAM metallopeptidase domain 19
chr2_-_207166818 1.92 ENST00000423015.5
Kruppel like factor 7
chr10_+_69801892 1.87 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr7_+_120988683 1.82 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr11_+_36296281 1.82 ENST00000530639.6
proline rich 5 like
chr1_-_65067707 1.80 ENST00000672099.1
ENST00000671954.1
ENST00000672434.1
ENST00000673502.1
ENST00000672751.1
Janus kinase 1
chr17_-_7394240 1.80 ENST00000576362.5
ENST00000571078.5
phospholipid scramblase 3
chr1_+_222928415 1.79 ENST00000284476.7
dispatched RND transporter family member 1
chr10_-_14572123 1.78 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
family with sequence similarity 107 member B
chr14_-_34875348 1.77 ENST00000360310.6
bromodomain adjacent to zinc finger domain 1A
chrX_+_101390824 1.75 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr11_+_65572349 1.72 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chr10_+_69802424 1.69 ENST00000673802.2
ENST00000517713.5
ENST00000520133.5
ENST00000522165.5
ENST00000673641.2
ENST00000673628.2
collagen type XIII alpha 1 chain
chr4_+_2818155 1.69 ENST00000511747.6
SH3 domain binding protein 2
chr20_+_57391388 1.67 ENST00000356208.10
ENST00000440234.6
RNA binding motif protein 38
chr7_-_140176970 1.65 ENST00000397560.7
lysine demethylase 7A
chr7_+_80646436 1.65 ENST00000419819.2
CD36 molecule
chr14_-_34874887 1.64 ENST00000382422.6
bromodomain adjacent to zinc finger domain 1A
chr11_-_5234475 1.62 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr7_+_150379316 1.60 ENST00000483664.5
ENST00000329630.10
novel transcript
zinc finger protein 775
chr6_-_27473058 1.60 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr15_+_75843438 1.59 ENST00000267938.9
ubiquitin conjugating enzyme E2 Q2
chr3_-_47781837 1.59 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr12_+_1629197 1.58 ENST00000397196.7
Wnt family member 5B
chr7_-_149028651 1.58 ENST00000286091.9
protein disulfide isomerase family A member 4
chr3_+_189631373 1.53 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr17_-_7394800 1.52 ENST00000574401.5
phospholipid scramblase 3
chr7_-_149028452 1.52 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr15_+_81000913 1.51 ENST00000267984.4
talin rod domain containing 1
chr10_+_21524670 1.47 ENST00000631589.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr7_+_80646305 1.47 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr6_-_151391539 1.45 ENST00000325144.5
zinc finger and BTB domain containing 2
chr13_+_23570370 1.44 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr12_+_55931148 1.43 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
diacylglycerol kinase alpha
chr14_+_58634055 1.41 ENST00000556859.5
ENST00000421793.5
dishevelled binding antagonist of beta catenin 1
chr15_+_64841873 1.41 ENST00000616065.4
ENST00000323544.5
pleckstrin homology domain containing O2
chr2_-_39121000 1.40 ENST00000402219.8
SOS Ras/Rac guanine nucleotide exchange factor 1
chr1_+_109548567 1.38 ENST00000369851.7
G protein subunit alpha i3
chr4_-_102345196 1.38 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr12_+_8913875 1.37 ENST00000538657.5
polyhomeotic homolog 1
chr15_-_101252040 1.36 ENST00000254190.4
chondroitin sulfate synthase 1
chr1_+_100351698 1.32 ENST00000644676.1
cell division cycle 14A
chr6_-_27472681 1.32 ENST00000377419.1
zinc finger protein 184
chr15_+_75843307 1.31 ENST00000569423.5
ubiquitin conjugating enzyme E2 Q2
chr7_-_27174274 1.30 ENST00000283921.5
homeobox A10
chrX_+_101390976 1.29 ENST00000392994.7
ribosomal protein L36a
chr14_+_20745880 1.27 ENST00000326842.3
epididymal protein 3A
chr15_+_40844064 1.25 ENST00000568823.5
serine peptidase inhibitor, Kunitz type 1
chr11_+_66231794 1.24 ENST00000528935.1
phosphofurin acidic cluster sorting protein 1
chr7_-_27180230 1.22 ENST00000396344.4
homeobox A10
chr19_+_55600277 1.21 ENST00000301073.4
zinc finger protein 524
chr21_+_29300111 1.20 ENST00000451655.5
BTB domain and CNC homolog 1
chr7_-_148884159 1.18 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr13_-_71867192 1.18 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
dachshund family transcription factor 1
chr22_-_31292445 1.17 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chrX_-_100928903 1.17 ENST00000372956.3
XK related X-linked
chrX_+_101391202 1.17 ENST00000471855.1
ribosomal protein L36a
chr8_+_101492751 1.16 ENST00000395927.1
grainyhead like transcription factor 2
chr2_-_9003657 1.16 ENST00000462696.1
ENST00000305997.8
membrane bound O-acyltransferase domain containing 2
chr2_+_176129680 1.16 ENST00000429017.2
ENST00000313173.6
homeobox D8
chr14_+_21852457 1.13 ENST00000390435.1
T cell receptor alpha variable 8-3
chr2_+_169066994 1.13 ENST00000357546.6
ENST00000432060.6
dehydrogenase/reductase 9
chr6_+_143608170 1.13 ENST00000427704.6
ENST00000305766.10
phosphatase and actin regulator 2
chr2_+_227813834 1.12 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr3_+_141387801 1.12 ENST00000514251.5
zinc finger and BTB domain containing 38
chr10_+_21524627 1.10 ENST00000651097.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr15_-_51751525 1.10 ENST00000454181.6
LysM domain containing 2
chr11_-_95232514 1.09 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr1_+_182839338 1.09 ENST00000367549.4
DExH-box helicase 9
chrX_-_19747574 1.07 ENST00000432234.5
SH3 domain containing kinase binding protein 1
chr6_-_33580229 1.07 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr14_+_21894433 1.06 ENST00000390438.2
T cell receptor alpha variable 8-4
chr7_-_27174253 1.05 ENST00000613671.1
homeobox A10
chr8_-_101206064 1.04 ENST00000518336.5
ENST00000520454.1
zinc finger protein 706
chr13_+_75760362 1.04 ENST00000534657.5
LIM domain 7
chr19_-_7926106 1.03 ENST00000318978.6
cortexin 1
chrX_+_101391000 1.03 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr3_+_179562886 1.02 ENST00000450518.6
ENST00000392662.5
ENST00000429709.7
ENST00000490364.1
actin like 6A
chr15_+_74782574 1.02 ENST00000567123.1
ENST00000569462.5
C-terminal Src kinase
chr14_-_22982258 1.01 ENST00000555074.1
ENST00000361265.8
novel protein
ajuba LIM protein
chr8_-_17246390 1.01 ENST00000520178.3
CCR4-NOT transcription complex subunit 7
chr8_-_69833338 0.98 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr7_-_148884266 0.97 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr20_+_41136944 0.96 ENST00000244007.7
phospholipase C gamma 1
chr8_+_38787218 0.96 ENST00000317827.9
ENST00000276520.12
transforming acidic coiled-coil containing protein 1
chr2_-_37324826 0.95 ENST00000234179.8
protein kinase D3
chr7_+_80646347 0.92 ENST00000413265.5
CD36 molecule
chr11_-_117876612 0.90 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr15_+_74782069 0.90 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr10_-_14572313 0.89 ENST00000479731.5
ENST00000468492.5
family with sequence similarity 107 member B
chr2_-_207167220 0.89 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr8_+_30095649 0.88 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr4_-_7939789 0.87 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr17_-_65560296 0.86 ENST00000585045.1
ENST00000611991.1
axin 2
chr2_-_159616442 0.85 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
bromodomain adjacent to zinc finger domain 2B
chr1_-_6419903 0.85 ENST00000377836.8
ENST00000487437.5
ENST00000489730.1
ENST00000377834.8
hes family bHLH transcription factor 2
chr12_-_49188811 0.84 ENST00000295766.9
tubulin alpha 1a
chr9_-_120926752 0.83 ENST00000373887.8
TNF receptor associated factor 1
chr7_+_114416286 0.83 ENST00000635534.1
forkhead box P2
chr18_+_6729698 0.82 ENST00000383472.9
Rho GTPase activating protein 28
chr1_+_43650466 0.82 ENST00000463151.5
lysine demethylase 4A
chrX_-_40097403 0.82 ENST00000397354.7
BCL6 corepressor
chr5_+_72816643 0.81 ENST00000337273.10
ENST00000523768.5
transportin 1
chr8_-_42377227 0.80 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr2_+_10043524 0.78 ENST00000305883.6
Kruppel like factor 11
chr12_+_53097656 0.78 ENST00000301464.4
insulin like growth factor binding protein 6
chr15_+_64841940 0.78 ENST00000437723.1
novel protein
chr19_-_40285395 0.75 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr5_+_132257670 0.75 ENST00000253754.8
ENST00000379018.7
PDZ and LIM domain 4
chr12_+_55931447 0.75 ENST00000549368.5
diacylglycerol kinase alpha
chr17_-_65561640 0.74 ENST00000618960.4
ENST00000307078.10
axin 2
chr2_+_9843426 0.72 ENST00000625239.2
ENST00000263663.10
TATA-box binding protein associated factor, RNA polymerase I subunit B
chr12_+_103965835 0.70 ENST00000266775.13
ENST00000544861.5
thymine DNA glycosylase
chr4_-_68349750 0.70 ENST00000579690.5
YTH domain containing 1
chr7_-_106285898 0.70 ENST00000424768.2
ENST00000681255.1
nicotinamide phosphoribosyltransferase
chr2_-_9630946 0.70 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr12_+_8914464 0.69 ENST00000544916.6
polyhomeotic homolog 1
chr8_+_30095400 0.69 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr10_-_14572087 0.67 ENST00000482277.5
ENST00000378462.5
family with sequence similarity 107 member B
chr10_-_97292625 0.67 ENST00000466484.1
ENST00000358531.9
ENST00000358308.7
Rho GTPase activating protein 19
chr8_-_17246590 0.67 ENST00000524358.5
CCR4-NOT transcription complex subunit 7
chr1_+_32013848 0.65 ENST00000327300.12
ENST00000492989.1
KH RNA binding domain containing, signal transduction associated 1
chr11_-_117876719 0.65 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr12_-_107761113 0.64 ENST00000228437.10
PR/SET domain 4
chr19_-_40285277 0.63 ENST00000579047.5
ENST00000392038.7
AKT serine/threonine kinase 2
chr5_+_66828762 0.63 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr16_-_15643024 0.62 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr12_+_103965798 0.61 ENST00000436021.6
thymine DNA glycosylase
chr4_+_112231748 0.60 ENST00000274000.10
ENST00000309703.10
adaptor related protein complex 1 associated regulatory protein
chr7_+_111091006 0.60 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chrX_-_16863021 0.60 ENST00000416035.1
RB binding protein 7, chromatin remodeling factor
chr16_+_2770911 0.59 ENST00000570539.1
serine/arginine repetitive matrix 2
chr20_-_63956382 0.58 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr10_-_14571969 0.57 ENST00000488576.5
ENST00000472095.5
family with sequence similarity 107 member B
chr2_-_37324696 0.57 ENST00000443187.1
protein kinase D3
chr7_-_106661148 0.55 ENST00000523505.3
coiled-coil domain containing 71 like
chr2_-_127811149 0.55 ENST00000322313.9
ENST00000393006.5
ENST00000409658.7
ENST00000436787.5
WD repeat domain 33
chr10_-_102419693 0.55 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr11_-_10808304 0.54 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chr3_+_133038366 0.54 ENST00000321871.11
ENST00000393130.7
ENST00000514894.5
ENST00000512662.5
transmembrane protein 108
chr19_+_40751179 0.53 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr12_+_55931070 0.52 ENST00000555090.5
diacylglycerol kinase alpha
chr3_-_126056786 0.52 ENST00000383598.6
solute carrier family 41 member 3
chr17_-_48613468 0.51 ENST00000498634.2
homeobox B8
chr1_-_42958836 0.51 ENST00000372500.4
ENST00000674765.1
ENST00000460369.3
ENST00000426263.10
solute carrier family 2 member 1
chr1_+_35883189 0.51 ENST00000674304.1
ENST00000373204.6
ENST00000674426.1
argonaute RISC component 1
chr12_-_49189053 0.51 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
tubulin alpha 1a
chr3_-_195542944 0.51 ENST00000625807.1
protein phosphatase 1 regulatory inhibitor subunit 2
chr4_-_156970903 0.50 ENST00000422544.2
platelet derived growth factor C
chr17_-_10518536 0.50 ENST00000226207.6
myosin heavy chain 1
chr9_-_72365198 0.50 ENST00000376962.10
ENST00000376960.8
zinc finger AN1-type containing 5
chrX_+_106920393 0.49 ENST00000336803.2
claudin 2
chr17_-_10469558 0.49 ENST00000255381.2
myosin heavy chain 4
chr12_-_107760928 0.49 ENST00000547188.1
PR/SET domain 4
chr2_-_69961624 0.49 ENST00000320256.6
aspartic peptidase retroviral like 1
chr11_-_65614195 0.48 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.1 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.7 2.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.7 4.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.7 8.7 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 5.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.6 3.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.6 1.8 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.6 1.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 2.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.5 5.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.4 1.7 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.4 2.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4 2.3 GO:1903232 melanosome assembly(GO:1903232)
0.4 1.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 10.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4 1.1 GO:0002339 B cell selection(GO:0002339)
0.3 1.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 1.8 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.3 1.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 1.4 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 0.8 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.3 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.7 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 1.9 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.7 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 2.8 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.1 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.2 0.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 1.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 5.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 1.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2 0.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 0.7 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.2 7.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.2 1.8 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 2.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 3.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 1.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 0.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 1.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.8 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 4.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 3.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.4 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.3 GO:0007320 insemination(GO:0007320)
0.1 2.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 5.1 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 1.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 1.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 4.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 5.5 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 2.4 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 5.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 1.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 5.2 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 1.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.7 GO:0051770 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 2.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 3.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.7 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.4 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.6 GO:0030850 prostate gland development(GO:0030850)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 1.0 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 1.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 1.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.8 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.8 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 4.9 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 3.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 1.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.6 GO:0007143 female meiotic division(GO:0007143)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.1 3.4 GO:0016590 ACF complex(GO:0016590)
0.6 1.8 GO:0075341 host cell PML body(GO:0075341)
0.6 5.3 GO:0035976 AP1 complex(GO:0035976)
0.5 15.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 2.3 GO:0031905 early endosome lumen(GO:0031905)
0.5 3.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.5 6.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.4 3.0 GO:0031523 Myb complex(GO:0031523)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 9.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0005584 collagen type I trimer(GO:0005584)
0.1 2.7 GO:0045120 pronucleus(GO:0045120)
0.1 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.9 GO:0031932 TORC2 complex(GO:0031932)
0.1 4.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.3 GO:0060091 kinocilium(GO:0060091)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.6 GO:0001741 XY body(GO:0001741)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.8 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 5.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 1.0 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 4.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 3.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.7 8.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 1.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4 1.1 GO:0045142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) triplex DNA binding(GO:0045142)
0.3 3.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 3.7 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.3 1.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 15.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 1.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 5.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 3.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 3.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.5 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2 2.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 3.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.7 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 5.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 1.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 1.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 6.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 2.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 2.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.8 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 3.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 5.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 5.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 7.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 4.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 6.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 7.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 7.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 6.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 3.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 5.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 4.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 4.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 5.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 8.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 3.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 10.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 3.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 5.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 3.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing