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avrg: Illumina Body Map 2 (GSE30611)

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Results for TEAD4

Z-value: 1.78

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Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
TEAD4
ENSG00000197905.10 TEAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD4hg38_v1_chr12_+_2959870_29599530.232.1e-01Click!

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_106335613 4.48 ENST00000603660.1
IGHV3-30
immunoglobulin heavy variable 3-30
chr14_-_106269133 4.38 ENST00000390609.3
IGHV3-23
immunoglobulin heavy variable 3-23
chr14_-_106360320 4.23 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr12_+_85874287 4.12 ENST00000551529.5
ENST00000256010.7
NTS
neurotensin
chr14_-_106593319 4.01 ENST00000390627.3
IGHV3-53
immunoglobulin heavy variable 3-53
chr17_-_31297231 3.60 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr14_-_106062670 3.24 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr14_-_105987068 3.10 ENST00000390594.3
IGHV1-2
immunoglobulin heavy variable 1-2
chr10_-_73651013 2.89 ENST00000372873.8
SYNPO2L
synaptopodin 2 like
chr14_-_106165730 2.59 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr2_-_157327699 2.49 ENST00000397283.6
ERMN
ermin
chr2_-_89160329 2.41 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr14_-_106803221 2.35 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr4_-_39032343 2.25 ENST00000381938.4
TMEM156
transmembrane protein 156
chr2_-_234497035 2.16 ENST00000390645.2
ENST00000339728.6
ARL4C
ADP ribosylation factor like GTPase 4C
chr17_+_34255274 2.13 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr16_+_32995048 2.09 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_-_106088573 1.86 ENST00000632099.1
IGHV3-64D
immunoglobulin heavy variable 3-64D
chr16_+_32847692 1.84 ENST00000567458.2
IGHV2OR16-5
immunoglobulin heavy variable 2/OR16-5 (non-functional)
chr6_-_32666648 1.84 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr12_+_6444932 1.81 ENST00000266557.4
CD27
CD27 molecule
chr11_+_60455839 1.77 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
MS4A1
membrane spanning 4-domains A1
chr16_+_33009175 1.62 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr5_+_54455661 1.58 ENST00000302005.3
HSPB3
heat shock protein family B (small) member 3
chr1_+_65992389 1.51 ENST00000423207.6
PDE4B
phosphodiesterase 4B
chr1_+_160796157 1.50 ENST00000263285.11
ENST00000368039.2
LY9
lymphocyte antigen 9
chr4_+_41612892 1.45 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr4_+_119135825 1.44 ENST00000307128.6
MYOZ2
myozenin 2
chr13_-_67230377 1.43 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr3_+_130560334 1.43 ENST00000358511.10
COL6A6
collagen type VI alpha 6 chain
chr3_-_52452828 1.38 ENST00000496590.1
TNNC1
troponin C1, slow skeletal and cardiac type
chr8_-_27258386 1.38 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
STMN4
stathmin 4
chr2_-_178807415 1.34 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
TTN
titin
chr14_-_106658251 1.33 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr20_+_44531817 1.32 ENST00000372889.5
ENST00000372887.5
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr8_-_27258414 1.29 ENST00000523048.5
STMN4
stathmin 4
chr3_+_101827982 1.28 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr2_-_136118142 1.28 ENST00000241393.4
CXCR4
C-X-C motif chemokine receptor 4
chr10_+_62049211 1.27 ENST00000309334.5
ARID5B
AT-rich interaction domain 5B
chr1_-_11848345 1.25 ENST00000376476.1
NPPA
natriuretic peptide A
chr2_+_33476640 1.23 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RASGRP3
RAS guanyl releasing protein 3
chr2_+_227813834 1.23 ENST00000358813.5
ENST00000409189.7
CCL20
C-C motif chemokine ligand 20
chr1_+_161706949 1.22 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
FCRLA
Fc receptor like A
chr2_+_90021567 1.21 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr7_+_54542393 1.19 ENST00000404951.5
VSTM2A
V-set and transmembrane domain containing 2A
chr2_-_42361149 1.19 ENST00000468711.5
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr1_-_101996919 1.16 ENST00000370103.9
OLFM3
olfactomedin 3
chrX_+_21374608 1.16 ENST00000644295.1
ENST00000645074.1
ENST00000645791.1
ENST00000643220.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr12_+_12725897 1.15 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr13_-_67230313 1.14 ENST00000377865.7
PCDH9
protocadherin 9
chr1_+_160081529 1.13 ENST00000368088.4
KCNJ9
potassium inwardly rectifying channel subfamily J member 9
chr19_+_9087061 1.13 ENST00000641627.1
OR1M1
olfactory receptor family 1 subfamily M member 1
chr6_-_159726871 1.13 ENST00000535561.5
SOD2
superoxide dismutase 2
chr12_+_10307818 1.12 ENST00000350274.9
ENST00000336164.9
KLRD1
killer cell lectin like receptor D1
chr6_-_56628018 1.11 ENST00000522360.5
DST
dystonin
chr7_+_54542362 1.10 ENST00000402613.4
VSTM2A
V-set and transmembrane domain containing 2A
chr20_-_57359491 1.10 ENST00000543500.3
MTRNR2L3
MT-RNR2 like 3
chr6_-_46325641 1.10 ENST00000330430.10
ENST00000405162.2
RCAN2
regulator of calcineurin 2
chrX_+_21374357 1.07 ENST00000643841.1
ENST00000379510.5
ENST00000425654.7
ENST00000644798.1
ENST00000543067.6
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr2_-_60553618 1.06 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr3_-_47891269 1.04 ENST00000335271.9
MAP4
microtubule associated protein 4
chr2_+_33458043 1.04 ENST00000437184.5
RASGRP3
RAS guanyl releasing protein 3
chr11_+_94706412 1.04 ENST00000299004.13
AMOTL1
angiomotin like 1
chr12_-_91146195 1.03 ENST00000548218.1
DCN
decorin
chr20_+_58841612 1.02 ENST00000462499.6
ENST00000482112.6
ENST00000663479.2
ENST00000493744.5
GNAS
GNAS complex locus
chr4_+_41612702 1.01 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr16_-_46763237 1.00 ENST00000536476.5
MYLK3
myosin light chain kinase 3
chr7_-_111788958 1.00 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr8_+_66493514 1.00 ENST00000521495.5
VXN
vexin
chr2_+_200440649 0.99 ENST00000366118.2
SPATS2L
spermatogenesis associated serine rich 2 like
chr7_-_36985060 0.97 ENST00000396040.6
ELMO1
engulfment and cell motility 1
chr1_+_163068775 0.97 ENST00000421743.6
RGS4
regulator of G protein signaling 4
chr7_+_87934242 0.95 ENST00000413139.2
ENST00000412441.5
ENST00000683525.1
ENST00000398201.8
ENST00000265727.11
ENST00000398209.7
ENST00000684002.1
ADAM22
ADAM metallopeptidase domain 22
chrX_+_21374476 0.94 ENST00000644585.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chrX_+_21374434 0.91 ENST00000279451.9
ENST00000645245.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr12_-_9733292 0.90 ENST00000621400.4
ENST00000327839.3
CLECL1
C-type lectin like 1
chr2_+_33476616 0.90 ENST00000442390.5
RASGRP3
RAS guanyl releasing protein 3
chr7_+_54542300 0.90 ENST00000302287.7
ENST00000407838.7
VSTM2A
V-set and transmembrane domain containing 2A
chr7_-_83648547 0.90 ENST00000642232.1
SEMA3E
semaphorin 3E
chr3_+_63443306 0.88 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
SYNPR
synaptoporin
chr2_-_60553558 0.88 ENST00000642439.1
ENST00000356842.9
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr1_+_32251239 0.88 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK
LCK proto-oncogene, Src family tyrosine kinase
chr12_-_48999363 0.87 ENST00000421952.3
DDN
dendrin
chr19_+_35139724 0.87 ENST00000588715.5
ENST00000588607.5
FXYD1
FXYD domain containing ion transport regulator 1
chr5_+_58583068 0.87 ENST00000282878.6
RAB3C
RAB3C, member RAS oncogene family
chr7_-_22194709 0.86 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr15_-_19988117 0.86 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr10_-_59753444 0.85 ENST00000594536.5
ENST00000414264.6
MRLN
myoregulin
chr18_+_54591159 0.84 ENST00000321600.1
ENST00000648945.2
DYNAP
dynactin associated protein
chr6_-_46015812 0.84 ENST00000544153.3
ENST00000339561.12
CLIC5
chloride intracellular channel 5
chr12_-_9760893 0.83 ENST00000228434.7
ENST00000536709.1
CD69
CD69 molecule
chr2_-_197676012 0.83 ENST00000429081.1
RFTN2
raftlin family member 2
chr7_+_148133684 0.82 ENST00000628930.2
CNTNAP2
contactin associated protein 2
chr3_+_124094663 0.82 ENST00000460856.5
ENST00000240874.7
KALRN
kalirin RhoGEF kinase
chr3_+_63443076 0.82 ENST00000295894.9
SYNPR
synaptoporin
chr15_+_33968484 0.81 ENST00000383263.7
CHRM5
cholinergic receptor muscarinic 5
chr4_+_185395979 0.81 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr19_+_35138993 0.80 ENST00000612146.4
ENST00000589209.5
FXYD1
FXYD domain containing ion transport regulator 1
chr1_+_43270007 0.79 ENST00000432792.6
TMEM125
transmembrane protein 125
chr6_+_31670167 0.78 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 family member G5B
chr7_+_142313144 0.78 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chrX_+_21374288 0.77 ENST00000642359.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr6_-_56642788 0.77 ENST00000439203.5
ENST00000518935.5
ENST00000370765.11
ENST00000244364.10
DST
dystonin
chr8_+_66493556 0.77 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
VXN
vexin
chr19_-_51417619 0.75 ENST00000441969.7
ENST00000339313.10
ENST00000525998.5
ENST00000436984.6
SIGLEC10
sialic acid binding Ig like lectin 10
chr5_-_124745315 0.75 ENST00000306315.9
ZNF608
zinc finger protein 608
chr5_+_173889337 0.75 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr6_-_134317629 0.74 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_120385286 0.74 ENST00000532993.5
ARHGEF12
Rho guanine nucleotide exchange factor 12
chr10_+_49299159 0.72 ENST00000374144.8
C10orf71
chromosome 10 open reading frame 71
chr19_+_35139440 0.71 ENST00000455515.6
FXYD1
FXYD domain containing ion transport regulator 1
chr7_+_151114597 0.70 ENST00000335367.7
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_+_43269974 0.70 ENST00000439858.6
TMEM125
transmembrane protein 125
chr5_-_41794211 0.70 ENST00000512084.5
OXCT1
3-oxoacid CoA-transferase 1
chr14_-_75063990 0.70 ENST00000555135.1
ENST00000357971.7
ENST00000553302.1
ENST00000238618.8
ENST00000555694.5
ACYP1
acylphosphatase 1
chr3_+_124094696 0.69 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
KALRN
kalirin RhoGEF kinase
chr18_+_58341038 0.69 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr7_-_81770122 0.69 ENST00000423064.7
HGF
hepatocyte growth factor
chr2_-_150539011 0.68 ENST00000439275.1
RND3
Rho family GTPase 3
chr4_+_118034480 0.68 ENST00000296499.6
NDST3
N-deacetylase and N-sulfotransferase 3
chr8_-_23854796 0.68 ENST00000290271.7
STC1
stanniocalcin 1
chr10_-_59753388 0.68 ENST00000430431.5
MRLN
myoregulin
chr17_+_4951758 0.67 ENST00000518175.1
ENO3
enolase 3
chr15_+_81182579 0.67 ENST00000302987.9
IL16
interleukin 16
chr6_-_134317905 0.67 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_78079773 0.66 ENST00000612612.5
ENST00000614236.2
NDUFC2-KCTD14
NDUFC2-KCTD14 readthrough
chr12_-_122526929 0.64 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
RSRC2
arginine and serine rich coiled-coil 2
chr4_+_146214515 0.63 ENST00000636502.1
REELD1
reeler domain containing 1
chr21_+_33432173 0.63 ENST00000421802.1
IFNGR2
interferon gamma receptor 2
chr15_+_80441229 0.62 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
ARNT2
aryl hydrocarbon receptor nuclear translocator 2
chr3_-_100847647 0.62 ENST00000528490.5
ABI3BP
ABI family member 3 binding protein
chr10_-_60389833 0.61 ENST00000280772.7
ANK3
ankyrin 3
chr5_-_41794547 0.61 ENST00000510634.5
OXCT1
3-oxoacid CoA-transferase 1
chrX_-_32412220 0.60 ENST00000619831.5
DMD
dystrophin
chr2_+_209771972 0.60 ENST00000439458.5
ENST00000272845.10
UNC80
unc-80 homolog, NALCN channel complex subunit
chr8_+_49911604 0.60 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
SNTG1
syntrophin gamma 1
chr11_-_102724781 0.60 ENST00000438475.2
MMP8
matrix metallopeptidase 8
chr4_+_36281591 0.59 ENST00000639862.2
ENST00000357504.7
DTHD1
death domain containing 1
chr3_-_194633689 0.59 ENST00000330115.3
TMEM44
transmembrane protein 44
chr7_-_82443715 0.58 ENST00000356253.9
ENST00000423588.1
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr7_-_81769971 0.58 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor
chr5_+_174045673 0.58 ENST00000303177.8
ENST00000519867.5
NSG2
neuronal vesicle trafficking associated 2
chr9_+_74497308 0.58 ENST00000376896.8
RORB
RAR related orphan receptor B
chr3_-_18424533 0.57 ENST00000417717.6
SATB1
SATB homeobox 1
chr12_+_32107296 0.57 ENST00000551086.1
BICD1
BICD cargo adaptor 1
chr10_+_122163672 0.57 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr12_-_39619782 0.57 ENST00000308666.4
ABCD2
ATP binding cassette subfamily D member 2
chr20_+_34977625 0.56 ENST00000618182.6
MYH7B
myosin heavy chain 7B
chr11_+_10455292 0.56 ENST00000396553.6
AMPD3
adenosine monophosphate deaminase 3
chr12_-_9733083 0.56 ENST00000542530.5
CLECL1
C-type lectin like 1
chr8_+_49911396 0.55 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr7_-_47948448 0.55 ENST00000289672.7
PKD1L1
polycystin 1 like 1, transient receptor potential channel interacting
chr12_-_124917340 0.55 ENST00000542416.1
UBC
ubiquitin C
chr3_-_69200711 0.55 ENST00000478263.5
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr15_-_38560050 0.55 ENST00000558432.5
RASGRP1
RAS guanyl releasing protein 1
chr1_-_27626106 0.54 ENST00000457296.5
FGR
FGR proto-oncogene, Src family tyrosine kinase
chr6_-_152637386 0.54 ENST00000610489.2
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr17_-_15272287 0.53 ENST00000674868.1
PMP22
peripheral myelin protein 22
chr17_-_36196748 0.53 ENST00000619989.1
CCL3L1
C-C motif chemokine ligand 3 like 1
chr18_+_63587336 0.53 ENST00000344731.10
SERPINB13
serpin family B member 13
chr3_-_197260369 0.53 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr19_+_9185594 0.53 ENST00000344248.4
OR7D2
olfactory receptor family 7 subfamily D member 2
chr18_+_63587297 0.52 ENST00000269489.9
SERPINB13
serpin family B member 13
chr1_+_161707205 0.52 ENST00000367957.7
FCRLA
Fc receptor like A
chr9_-_101487120 0.52 ENST00000374848.8
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr6_+_31670379 0.52 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 family member G5B
chr8_-_69833338 0.52 ENST00000524945.5
SLCO5A1
solute carrier organic anion transporter family member 5A1
chr4_+_94489030 0.50 ENST00000510099.5
PDLIM5
PDZ and LIM domain 5
chr21_-_38498415 0.50 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr2_-_187554473 0.50 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr11_+_59511539 0.50 ENST00000641962.1
OR4D9
olfactory receptor family 4 subfamily D member 9
chr8_-_42502496 0.50 ENST00000522707.1
SLC20A2
solute carrier family 20 member 2
chr3_-_54928044 0.49 ENST00000273286.6
LRTM1
leucine rich repeats and transmembrane domains 1
chr19_-_3786408 0.49 ENST00000395040.6
MATK
megakaryocyte-associated tyrosine kinase
chr4_+_70430487 0.49 ENST00000413702.5
MUC7
mucin 7, secreted
chr2_+_190927649 0.48 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr9_-_73865 0.48 ENST00000642633.1
WASHC1
WASH complex subunit 1
chr1_-_211492111 0.48 ENST00000367002.5
ENST00000680073.1
RD3
RD3 regulator of GUCY2D
chr6_-_27867581 0.48 ENST00000331442.5
H1-5
H1.5 linker histone, cluster member
chr22_-_50085378 0.47 ENST00000442311.1
MLC1
modulator of VRAC current 1
chr2_-_44323302 0.47 ENST00000420756.1
ENST00000444696.5
PREPL
prolyl endopeptidase like
chr13_-_44437214 0.47 ENST00000622051.1
TSC22D1
TSC22 domain family member 1
chr4_+_153222402 0.47 ENST00000676335.1
ENST00000675146.1
TRIM2
tripartite motif containing 2
chr17_+_46713149 0.47 ENST00000576346.5
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr10_-_113664033 0.46 ENST00000359988.4
ENST00000369360.7
ENST00000360478.7
ENST00000369358.8
NRAP
nebulin related anchoring protein
chr1_+_15684284 0.46 ENST00000375799.8
ENST00000375793.2
PLEKHM2
pleckstrin homology and RUN domain containing M2
chr1_+_161707222 0.46 ENST00000236938.12
FCRLA
Fc receptor like A
chr7_-_13989658 0.46 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETV1
ETS variant transcription factor 1
chr6_-_152168349 0.46 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr12_+_10307950 0.46 ENST00000543420.5
ENST00000543777.5
KLRD1
killer cell lectin like receptor D1
chr19_-_3786363 0.46 ENST00000310132.11
MATK
megakaryocyte-associated tyrosine kinase
chr19_-_3786254 0.46 ENST00000585778.5
MATK
megakaryocyte-associated tyrosine kinase
chr4_-_20984011 0.46 ENST00000382149.9
KCNIP4
potassium voltage-gated channel interacting protein 4
chr12_+_108129276 0.46 ENST00000547525.6
WSCD2
WSC domain containing 2
chr17_-_18682262 0.45 ENST00000454745.2
ENST00000395675.7
FOXO3B
forkhead box O3B
chr8_+_24294044 0.45 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr2_-_189225175 0.45 ENST00000649966.1
COL5A2
collagen type V alpha 2 chain
chr6_-_154247630 0.45 ENST00000519344.5
IPCEF1
interaction protein for cytohesin exchange factors 1
chr5_-_139482714 0.45 ENST00000652543.1
STING1
stimulator of interferon response cGAMP interactor 1
chr8_-_133499320 0.44 ENST00000523855.1
ENST00000523854.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.6 3.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.4 2.2 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.4 1.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 1.1 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.3 1.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.4 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3 2.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 1.2 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 1.5 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.3 2.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 1.1 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.2 0.9 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.2 1.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.2 17.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 1.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 17.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.1 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.3 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.5 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.1 1.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.1 0.8 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 1.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1 1.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.5 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.6 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.5 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.1 1.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.4 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.0 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 1.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0032258 CVT pathway(GO:0032258) G-protein coupled receptor catabolic process(GO:1990172)
0.0 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 2.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 2.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 3.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 2.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.9 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.1 GO:0016577 histone demethylation(GO:0016577)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.8 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.6 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 2.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.8 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 1.9 GO:0046718 viral entry into host cell(GO:0046718)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 1.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.9 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.2 1.9 GO:0031673 H zone(GO:0031673)
0.2 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 2.5 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 4.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 1.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0033010 paranodal junction(GO:0033010)
0.0 1.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 4.1 GO:0043679 axon terminus(GO:0043679)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 1.3 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0043218 compact myelin(GO:0043218)
0.0 10.4 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 5.2 GO:0030426 growth cone(GO:0030426)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 4.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 1.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.3 1.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 1.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 17.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.4 GO:0051373 FATZ binding(GO:0051373)
0.1 1.4 GO:0031013 troponin I binding(GO:0031013)
0.1 5.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 3.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 26.3 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.3 GO:0031433 telethonin binding(GO:0031433)
0.1 0.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.3 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 4.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.0 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 2.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.1 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0090079 translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.7 GO:0008137 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 7.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.1 ST ADRENERGIC Adrenergic Pathway
0.0 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 6.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 3.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 3.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.6 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis