ISMARA results: THRA

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avrg: Illumina Body Map 2 (GSE30611)

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Results for THRA_RXRB

Z-value: 2.43

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Transcription factors associated with THRA_RXRB

Gene Symbol	Gene ID	Gene Info
THRA Ensembl NCBI GeneCards UniProt	ENSG00000126351.13	THRA
RXRB Ensembl NCBI GeneCards UniProt	ENSG00000204231.11	RXRB

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RXRB	hg38_v1_chr6_-_33200614_33200680	0.22	2.4e-01	Click!
THRA	hg38_v1_chr17_+_40062956_40062978	-0.15	4.3e-01	Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr22_+_22922594 Show fit	15.15	ENST00000390331.3	IGLC7 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 7
chr14_-_105708627 Show fit	10.56	ENST00000641837.1 ENST00000390547.3	IGHA1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 1
chr14_-_105588322 Show fit	9.19	ENST00000497872.4 ENST00000390539.2	IGHA2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_22792485 Show fit	8.59	ENST00000390314.2	IGLV2-11 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-11
chr1_-_150720842 Show fit	8.30	ENST00000442853.5 ENST00000368995.8 ENST00000322343.11 ENST00000361824.7	HORMAD1 Ensembl NCBI GeneCards UniProt Show fit	HORMA domain containing 1
chr22_+_22758698 Show fit	8.24	ENST00000390312.2	IGLV2-14 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-14
chr22_+_22409755 Show fit	7.94	ENST00000390299.2	IGLV1-40 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-40
chr22_+_22822658 Show fit	6.51	ENST00000620395.2	IGLV2-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-8
chr22_+_22734577 Show fit	5.71	ENST00000390310.3	IGLV2-18 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-18
chr1_+_178513103 Show fit	5.03	ENST00000319416.7 ENST00000367643.7 ENST00000367642.3 ENST00000367641.7 ENST00000367639.1	TEX35 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 35
chr22_+_22900976 Show fit	4.93	ENST00000390323.2	IGLC2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 2
chr22_+_22431949 Show fit	4.79	ENST00000390301.3	IGLV1-36 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-36
chr22_+_22668286 Show fit	4.46	ENST00000390304.2	IGLV3-27 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-27
chr22_+_22098683 Show fit	4.41	ENST00000390283.2	IGLV8-61 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 8-61
chr16_+_85908988 Show fit	4.27	ENST00000566369.1	IRF8 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 8
chr1_-_150720829 Show fit	4.24	ENST00000368987.5	HORMAD1 Ensembl NCBI GeneCards UniProt Show fit	HORMA domain containing 1
chr22_+_22327298 Show fit	4.20	ENST00000390291.2	IGLV1-50 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-50 (non-functional)
chr22_-_28741783 Show fit	3.83	ENST00000439200.5 ENST00000405598.5 ENST00000398017.3 ENST00000649563.1 ENST00000650281.1 ENST00000425190.7 ENST00000404276.6 ENST00000650233.1 ENST00000348295.7 ENST00000382580.6	CHEK2 Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr7_+_100589573 Show fit	3.72	ENST00000468962.5 ENST00000427939.2	FBXO24 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 24
chr19_-_39335999 Show fit	3.71	ENST00000602185.5 ENST00000598034.5 ENST00000601387.5 ENST00000595636.1 ENST00000253054.12 ENST00000594700.5 ENST00000597595.6	GMFG Ensembl NCBI GeneCards UniProt Show fit	glia maturation factor gamma
chr22_+_22195753 Show fit	3.71	ENST00000390285.4	IGLV6-57 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 6-57
chr1_+_32362537 Show fit	3.42	ENST00000373534.4	TSSK3 Ensembl NCBI GeneCards UniProt Show fit	testis specific serine kinase 3
chr5_+_40679907 Show fit	3.39	ENST00000302472.4	PTGER4 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin E receptor 4
chr1_-_32362081 Show fit	3.38	ENST00000432622.1	FAM229A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 229 member A
chr7_+_128791968 Show fit	3.19	ENST00000297788.9 ENST00000487361.5	CCDC136 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 136
chr12_-_52601458 Show fit	3.13	ENST00000537672.6 ENST00000293745.7	KRT72 Ensembl NCBI GeneCards UniProt Show fit	keratin 72
chr22_+_22162155 Show fit	3.06	ENST00000390284.2	IGLV4-60 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-60
chr11_-_123885627 Show fit	2.96	ENST00000528595.1 ENST00000375026.7	TMEM225 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 225
chr3_+_10026409 Show fit	2.95	ENST00000287647.7 ENST00000676013.1 ENST00000675286.1 ENST00000419585.5	FANCD2 Ensembl NCBI GeneCards UniProt Show fit	FA complementation group D2
chr22_+_22343185 Show fit	2.90	ENST00000427632.2	IGLV9-49 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 9-49
chr20_-_13990609 Show fit	2.87	ENST00000284951.10 ENST00000378072.5	SEL1L2 Ensembl NCBI GeneCards UniProt Show fit	SEL1L2 adaptor subunit of ERAD E3 ligase
chr14_-_23567734 Show fit	2.85	ENST00000556843.1 ENST00000397120.8 ENST00000557189.5	AP1G2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit gamma 2
chr19_+_49335396 Show fit	2.80	ENST00000598095.5 ENST00000426897.6 ENST00000323906.9 ENST00000535669.6 ENST00000597602.1 ENST00000595660.1	CD37 Ensembl NCBI GeneCards UniProt Show fit	CD37 molecule
chrX_-_71106728 Show fit	2.76	ENST00000374251.6	CXorf65 Ensembl NCBI GeneCards UniProt Show fit	chromosome X open reading frame 65
chr22_+_22357739 Show fit	2.71	ENST00000390294.2	IGLV1-47 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 1-47
chr5_+_163460623 Show fit	2.66	ENST00000393915.9 ENST00000432118.6	HMMR Ensembl NCBI GeneCards UniProt Show fit	hyaluronan mediated motility receptor
chr14_-_24609660 Show fit	2.44	ENST00000557220.6 ENST00000216338.9 ENST00000382548.4	GZMH Ensembl NCBI GeneCards UniProt Show fit	granzyme H
chr16_-_50681289 Show fit	2.43	ENST00000423026.6 ENST00000330943.9	SNX20 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 20
chr20_+_44715360 Show fit	2.40	ENST00000190983.5	CCN5 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 5
chr19_-_55363243 Show fit	2.33	ENST00000424985.3	FAM71E2 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 71 member E2
chr16_-_11273610 Show fit	2.31	ENST00000327157.4	PRM3 Ensembl NCBI GeneCards UniProt Show fit	protamine 3
chr16_-_58295019 Show fit	2.29	ENST00000567164.6 ENST00000219301.8 ENST00000569727.1	PRSS54 Ensembl NCBI GeneCards UniProt Show fit	serine protease 54
chr19_+_48606732 Show fit	2.11	ENST00000321762.3	SPACA4 Ensembl NCBI GeneCards UniProt Show fit	sperm acrosome associated 4
chr2_+_218880844 Show fit	2.11	ENST00000258411.8	WNT10A Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 10A
chr19_+_16076485 Show fit	2.06	ENST00000643579.2 ENST00000646575.1	TPM4 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 4
chrX_-_30309387 Show fit	2.05	ENST00000378970.5	NR0B1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 0 group B member 1
chr8_+_102551583 Show fit	1.98	ENST00000285402.4	ODF1 Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 1
chr9_-_124595808 Show fit	1.96	ENST00000475178.1	NR6A1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 6 group A member 1
chr1_-_159925496 Show fit	1.87	ENST00000368097.9	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr11_-_5509929 Show fit	1.84	ENST00000311659.5 ENST00000445998.1	UBQLN3 Ensembl NCBI GeneCards UniProt Show fit	ubiquilin 3
chr16_-_58294976 Show fit	1.83	ENST00000543437.5 ENST00000569079.1	PRSS54 Ensembl NCBI GeneCards UniProt Show fit	serine protease 54
chr4_+_89901979 Show fit	1.83	ENST00000508372.1	MMRN1 Ensembl NCBI GeneCards UniProt Show fit	multimerin 1
chr12_-_52601507 Show fit	1.79	ENST00000354310.4	KRT72 Ensembl NCBI GeneCards UniProt Show fit	keratin 72
chr2_+_231592858 Show fit	1.78	ENST00000313965.4	TEX44 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 44
chr1_+_160177386 Show fit	1.77	ENST00000470705.1	ATP1A4 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 4
chr6_+_21593742 Show fit	1.74	ENST00000244745.4	SOX4 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 4
chr3_+_45026296 Show fit	1.73	ENST00000296130.5	CLEC3B Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 3 member B
chr19_+_53867874 Show fit	1.72	ENST00000448420.5 ENST00000439000.5 ENST00000391771.1 ENST00000391770.9	MYADM Ensembl NCBI GeneCards UniProt Show fit	myeloid associated differentiation marker
chr8_-_141507230 Show fit	1.71	ENST00000621837.1	MROH5 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 5 (gene/pseudogene)
chr16_-_29745951 Show fit	1.70	ENST00000329410.4	C16orf54 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 54
chr1_+_212624472 Show fit	1.69	ENST00000294829.5	FAM71A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 71 member A
chr6_+_139135063 Show fit	1.69	ENST00000367658.3	HECA Ensembl NCBI GeneCards UniProt Show fit	hdc homolog, cell cycle regulator
chr14_-_105601728 Show fit	1.69	ENST00000641420.1 ENST00000390541.2	IGHE Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy constant epsilon
chr14_+_22052503 Show fit	1.68	ENST00000390449.3	TRAV21 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 21
chr9_+_136980211 Show fit	1.67	ENST00000444903.2	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase
chr13_-_46182136 Show fit	1.66	ENST00000323076.7	LCP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 1
chr2_+_55232359 Show fit	1.65	ENST00000449323.5	RPS27A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27a
chr17_+_6996042 Show fit	1.65	ENST00000251535.11	ALOX12 Ensembl NCBI GeneCards UniProt Show fit	arachidonate 12-lipoxygenase, 12S type
chr22_+_22214765 Show fit	1.63	ENST00000390287.2	IGLV10-54 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 10-54
chr11_-_26572130 Show fit	1.61	ENST00000527569.1	MUC15 Ensembl NCBI GeneCards UniProt Show fit	mucin 15, cell surface associated
chr20_+_33662310 Show fit	1.61	ENST00000375222.4	C20orf144 Ensembl NCBI GeneCards UniProt Show fit	chromosome 20 open reading frame 144
chr2_+_55232672 Show fit	1.61	ENST00000404735.1 ENST00000272317.11	RPS27A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27a
chr20_+_38962299 Show fit	1.60	ENST00000373325.6 ENST00000373323.8 ENST00000252011.8 ENST00000615559.1	DHX35 Ensembl NCBI GeneCards UniProt Show fit ENSG00000277581.1 Ensembl NCBI GeneCards UniProt Show fit	DEAH-box helicase 35 novel transcript, sense intronic to DHX35
chr11_+_122838492 Show fit	1.58	ENST00000227348.9	CRTAM Ensembl NCBI GeneCards UniProt Show fit	cytotoxic and regulatory T cell molecule
chr16_-_72172135 Show fit	1.57	ENST00000537465.5 ENST00000237353.15	PMFBP1 Ensembl NCBI GeneCards UniProt Show fit	polyamine modulated factor 1 binding protein 1
chr20_-_33004307 Show fit	1.53	ENST00000420875.5 ENST00000375519.2 ENST00000375523.7 ENST00000356173.8	SUN5 Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 5
chr2_-_191151568 Show fit	1.52	ENST00000358470.8 ENST00000432798.1 ENST00000450994.1	STAT4 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 4
chr15_-_34337462 Show fit	1.51	ENST00000676379.1	SLC12A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 6
chr15_-_34338033 Show fit	1.51	ENST00000558667.5 ENST00000561120.5 ENST00000559236.5 ENST00000397702.6	SLC12A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 6
chr6_-_88963573 Show fit	1.48	ENST00000369485.9	RNGTT Ensembl NCBI GeneCards UniProt Show fit	RNA guanylyltransferase and 5'-phosphatase
chr9_+_36572854 Show fit	1.39	ENST00000543751.5 ENST00000536860.5 ENST00000541717.4 ENST00000536329.5 ENST00000536987.5 ENST00000298048.7 ENST00000495529.5 ENST00000545008.5	MELK Ensembl NCBI GeneCards UniProt Show fit	maternal embryonic leucine zipper kinase
chr1_+_44746401 Show fit	1.37	ENST00000372217.5	KIF2C Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 2C
chr7_+_128672275 Show fit	1.36	ENST00000684498.1 ENST00000641605.1 ENST00000682356.1 ENST00000477515.3	FAM71F2 Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 71 member F2
chr15_+_45129933 Show fit	1.35	ENST00000321429.8 ENST00000389037.7 ENST00000558322.5	DUOX1 Ensembl NCBI GeneCards UniProt Show fit	dual oxidase 1
chr11_+_64340191 Show fit	1.33	ENST00000356786.10	CCDC88B Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88B
chr8_-_130016395 Show fit	1.32	ENST00000523509.5	CYRIB Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr5_-_150449676 Show fit	1.30	ENST00000312037.6	RPS14 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr19_+_40611863 Show fit	1.29	ENST00000601032.5	LTBP4 Ensembl NCBI GeneCards UniProt Show fit	latent transforming growth factor beta binding protein 4
chr7_+_128791390 Show fit	1.29	ENST00000459946.5 ENST00000378685.8 ENST00000464832.5 ENST00000472049.1 ENST00000488925.1	CCDC136 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 136
chr1_-_149927756 Show fit	1.27	ENST00000271628.9	SF3B4 Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3b subunit 4
chr5_-_150449731 Show fit	1.27	ENST00000407193.7	RPS14 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr12_-_114406133 Show fit	1.26	ENST00000405440.7	TBX5 Ensembl NCBI GeneCards UniProt Show fit	T-box transcription factor 5
chr2_+_230996115 Show fit	1.25	ENST00000424440.5 ENST00000452881.5 ENST00000433428.6 ENST00000455816.1 ENST00000440792.5 ENST00000423134.1	SPATA3 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 3
chr20_+_3796288 Show fit	1.25	ENST00000439880.6 ENST00000245960.10	CDC25B Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25B
chr19_-_10339610 Show fit	1.25	ENST00000589261.5 ENST00000160262.10 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3 Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr9_+_35042213 Show fit	1.23	ENST00000378745.3 ENST00000312292.6	C9orf131 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 131
chrX_+_13569593 Show fit	1.21	ENST00000361306.6 ENST00000380602.3	EGFL6 Ensembl NCBI GeneCards UniProt Show fit	EGF like domain multiple 6
chr17_+_60422483 Show fit	1.21	ENST00000269127.5	C17orf64 Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 64
chr8_-_130016536 Show fit	1.19	ENST00000519020.5	CYRIB Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr8_+_85987287 Show fit	1.19	ENST00000521564.1	ATP6V0D2 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V0 subunit d2
chr5_-_132866884 Show fit	1.18	ENST00000624492.3 ENST00000621295.4	GDF9 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 9
chr12_+_102120172 Show fit	1.18	ENST00000327680.7 ENST00000541394.5 ENST00000543784.5	PARPBP Ensembl NCBI GeneCards UniProt Show fit	PARP1 binding protein
chr22_-_37188281 Show fit	1.16	ENST00000397110.6	C1QTNF6 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 6
chr19_-_51065067 Show fit	1.16	ENST00000595547.5 ENST00000335422.3 ENST00000595793.6 ENST00000596955.1	KLK13 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 13
chr9_-_86259604 Show fit	1.16	ENST00000376001.7 ENST00000339137.7	C9orf153 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 153
chr22_+_50738198 Show fit	1.16	ENST00000216139.10 ENST00000529621.1	ACR Ensembl NCBI GeneCards UniProt Show fit	acrosin
chr1_-_175192911 Show fit	1.15	ENST00000444639.5	KIAA0040 Ensembl NCBI GeneCards UniProt Show fit	KIAA0040
chr21_-_31558977 Show fit	1.15	ENST00000286827.7 ENST00000541036.5	TIAM1 Ensembl NCBI GeneCards UniProt Show fit	TIAM Rac1 associated GEF 1
chr16_+_67666770 Show fit	1.14	ENST00000403458.9 ENST00000602365.1	C16orf86 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 86
chr1_+_54641806 Show fit	1.14	ENST00000409996.5	MROH7 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 7
chr15_-_34337719 Show fit	1.12	ENST00000559484.1 ENST00000558589.5 ENST00000458406.6	SLC12A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 6
chr8_-_130016622 Show fit	1.11	ENST00000518283.5 ENST00000519110.5	CYRIB Ensembl NCBI GeneCards UniProt Show fit	CYFIP related Rac1 interactor B
chr14_-_76826229 Show fit	1.09	ENST00000557497.1	ANGEL1 Ensembl NCBI GeneCards UniProt Show fit	angel homolog 1
chr3_-_126558926 Show fit	1.09	ENST00000318225.3	C3orf22 Ensembl NCBI GeneCards UniProt Show fit	chromosome 3 open reading frame 22
chr16_-_1884231 Show fit	1.09	ENST00000563416.3 ENST00000633813.1 ENST00000470044.5	LINC00254 Ensembl NCBI GeneCards UniProt Show fit MEIOB Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 254 meiosis specific with OB-fold
chr10_+_100998676 Show fit	1.08	ENST00000481129.1	LZTS2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper tumor suppressor 2
chr3_-_179604648 Show fit	1.08	ENST00000392659.2	MRPL47 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L47
chr11_-_58575846 Show fit	1.07	ENST00000395074.7	LPXN Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr1_+_20070156 Show fit	1.05	ENST00000375108.4	PLA2G5 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group V
chr16_+_31355215 Show fit	1.05	ENST00000562522.2	ITGAX Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha X
chr14_-_58427114 Show fit	1.04	ENST00000556007.6	TIMM9 Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 9
chr1_+_54641754 Show fit	1.04	ENST00000339553.9 ENST00000421030.7	MROH7 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 7
chr18_+_63476927 Show fit	1.01	ENST00000489441.5 ENST00000382771.9 ENST00000424602.1	SERPINB5 Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 5
chr19_-_35228699 Show fit	1.01	ENST00000324675.3	FAM187B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 187 member B
chr16_-_57536543 Show fit	1.01	ENST00000258214.3	CCDC102A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 102A
chr22_+_22871478 Show fit	1.01	ENST00000390318.2	IGLV4-3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 4-3
chr5_+_136058849 Show fit	1.00	ENST00000508076.5	TGFBI Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta induced
chr21_+_43719095 Show fit	0.99	ENST00000468090.5 ENST00000291565.9	PDXK Ensembl NCBI GeneCards UniProt Show fit	pyridoxal kinase
chr6_-_31815244 Show fit	0.98	ENST00000375654.5	HSPA1L Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1 like
chr13_-_75537805 Show fit	0.97	ENST00000626103.1 ENST00000682242.1 ENST00000355801.4	COMMD6 Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 6
chr16_+_4734519 Show fit	0.96	ENST00000299320.10	C16orf71 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 71
chr1_+_196652022 Show fit	0.95	ENST00000367429.9 ENST00000630130.2 ENST00000359637.2	CFH Ensembl NCBI GeneCards UniProt Show fit	complement factor H
chr16_+_4734278 Show fit	0.95	ENST00000586724.5	C16orf71 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 71
chr14_+_88385643 Show fit	0.95	ENST00000393545.9 ENST00000356583.9 ENST00000555401.5 ENST00000553885.5	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr1_+_154327737 Show fit	0.95	ENST00000672630.1	ATP8B2 Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 8B2
chr14_-_58427134 Show fit	0.94	ENST00000555930.6	TIMM9 Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 9
chr17_+_45844875 Show fit	0.94	ENST00000329196.7	SPPL2C Ensembl NCBI GeneCards UniProt Show fit	signal peptide peptidase like 2C
chr6_+_31815532 Show fit	0.94	ENST00000375651.7 ENST00000608703.1	HSPA1A Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family A (Hsp70) member 1A
chr1_+_54641816 Show fit	0.94	ENST00000395690.6	MROH7 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 7
chr16_-_50681206 Show fit	0.92	ENST00000610485.1	SNX20 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 20
chr19_+_49363074 Show fit	0.91	ENST00000597873.5	DKKL1 Ensembl NCBI GeneCards UniProt Show fit	dickkopf like acrosomal protein 1
chr7_+_23710203 Show fit	0.91	ENST00000422637.5 ENST00000355870.8	STK31 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 31
chr15_+_43791842 Show fit	0.91	ENST00000674451.1 ENST00000630046.2	SERF2 Ensembl NCBI GeneCards UniProt Show fit	small EDRK-rich factor 2
chr9_+_113536497 Show fit	0.91	ENST00000462143.5	RGS3 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 3
chr22_-_37188233 Show fit	0.90	ENST00000434784.1 ENST00000337843.7	C1QTNF6 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 6
chr7_-_37448845 Show fit	0.90	ENST00000310758.9	ELMO1 Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 1
chr15_+_78266181 Show fit	0.89	ENST00000446172.2	DNAJA4 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member A4
chr12_-_121580954 Show fit	0.89	ENST00000536437.5 ENST00000611216.4 ENST00000538046.6 ENST00000377071.9	KDM2B Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 2B
chr3_-_183555696 Show fit	0.89	ENST00000341319.8	KLHL6 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 6
chr7_+_23710326 Show fit	0.88	ENST00000354639.7 ENST00000531170.5 ENST00000444333.2	STK31 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 31
chr1_-_7853054 Show fit	0.88	ENST00000361696.10	UTS2 Ensembl NCBI GeneCards UniProt Show fit	urotensin 2
chr14_-_103562257 Show fit	0.88	ENST00000337322.4 ENST00000445922.2	BAG5 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 5
chr9_+_137251261 Show fit	0.88	ENST00000620243.4 ENST00000388931.7 ENST00000412566.5 ENST00000611378.4	STPG3 Ensembl NCBI GeneCards UniProt Show fit	sperm-tail PG-rich repeat containing 3
chr5_-_177554545 Show fit	0.87	ENST00000514747.6	FAM193B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 193 member B
chr15_+_74619089 Show fit	0.87	ENST00000562670.5 ENST00000564096.1	CLK3 Ensembl NCBI GeneCards UniProt Show fit	CDC like kinase 3
chr8_-_144527006 Show fit	0.87	ENST00000533758.1 ENST00000529415.7	LRRC24 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 24
chr15_-_34337772 Show fit	0.86	ENST00000354181.8	SLC12A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 6
chr14_-_54902807 Show fit	0.85	ENST00000543643.6 ENST00000536224.2 ENST00000395514.5 ENST00000491895.7	GCH1 Ensembl NCBI GeneCards UniProt Show fit	GTP cyclohydrolase 1
chr2_-_229921963 Show fit	0.84	ENST00000343290.5 ENST00000389044.8 ENST00000675453.1 ENST00000675903.1 ENST00000283943.9	TRIP12 Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 12
chr7_+_23710263 Show fit	0.84	ENST00000433467.6	STK31 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 31
chr5_-_150449696 Show fit	0.83	ENST00000401695.8	RPS14 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr17_+_62380553 Show fit	0.83	ENST00000305286.8 ENST00000520404.5 ENST00000518576.1	EFCAB3 Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 3
chrX_-_133753681 Show fit	0.82	ENST00000406757.2	GPC3 Ensembl NCBI GeneCards UniProt Show fit	glypican 3
chr14_+_88385714 Show fit	0.82	ENST00000045347.11	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr2_-_55232158 Show fit	0.81	ENST00000407122.5 ENST00000401408.6	CLHC1 Ensembl NCBI GeneCards UniProt Show fit	clathrin heavy chain linker domain containing 1
chr3_+_113532508 Show fit	0.81	ENST00000264852.9	SIDT1 Ensembl NCBI GeneCards UniProt Show fit	SID1 transmembrane family member 1
chr22_-_29388530 Show fit	0.80	ENST00000357586.7 ENST00000432560.6 ENST00000405198.6 ENST00000317368.11	AP1B1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit beta 1
chr5_+_119629552 Show fit	0.80	ENST00000613773.4 ENST00000620555.4 ENST00000515256.5 ENST00000509264.1	FAM170A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 170 member A
chr16_+_4734457 Show fit	0.80	ENST00000590191.1	C16orf71 Ensembl NCBI GeneCards UniProt Show fit	chromosome 16 open reading frame 71
chr14_-_103562637 Show fit	0.78	ENST00000299204.6	BAG5 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 5
chr7_+_5045821 Show fit	0.78	ENST00000353796.7 ENST00000396912.2 ENST00000396904.2	RBAK Ensembl NCBI GeneCards UniProt Show fit RBAK-RBAKDN Ensembl NCBI GeneCards UniProt Show fit	RB associated KRAB zinc finger RBAK-RBAKDN readthrough
chr1_-_203175783 Show fit	0.78	ENST00000621380.1 ENST00000255416.9	MYBPH Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein H
chr2_+_196713117 Show fit	0.78	ENST00000409270.5	CCDC150 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 150
chr14_+_22883220 Show fit	0.78	ENST00000536884.1 ENST00000267396.9	REM2 Ensembl NCBI GeneCards UniProt Show fit	RRAD and GEM like GTPase 2
chr8_-_143331811 Show fit	0.78	ENST00000522041.5	TOP1MT Ensembl NCBI GeneCards UniProt Show fit	DNA topoisomerase I mitochondrial
chr8_+_144012273 Show fit	0.77	ENST00000377470.8	SPATC1 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis and centriole associated 1
chr2_+_74530018 Show fit	0.77	ENST00000437202.1	HTRA2 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 2
chr3_-_179604628 Show fit	0.76	ENST00000476781.6 ENST00000259038.6	MRPL47 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L47
chr17_+_28744034 Show fit	0.74	ENST00000444415.7 ENST00000262396.10	TRAF4 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr17_-_5234801 Show fit	0.74	ENST00000571800.5 ENST00000574081.6 ENST00000399600.8 ENST00000574297.1	SCIMP Ensembl NCBI GeneCards UniProt Show fit	SLP adaptor and CSK interacting membrane protein
chr8_-_143568854 Show fit	0.73	ENST00000524906.5 ENST00000532862.1 ENST00000534459.5	MROH6 Ensembl NCBI GeneCards UniProt Show fit	maestro heat like repeat family member 6
chr2_-_55232352 Show fit	0.72	ENST00000451916.1	CLHC1 Ensembl NCBI GeneCards UniProt Show fit	clathrin heavy chain linker domain containing 1
chr4_+_20253500 Show fit	0.72	ENST00000622093.4 ENST00000273739.9	SLIT2 Ensembl NCBI GeneCards UniProt Show fit	slit guidance ligand 2
chr3_-_79019444 Show fit	0.72	ENST00000618833.4 ENST00000436010.6 ENST00000618846.4	ROBO1 Ensembl NCBI GeneCards UniProt Show fit	roundabout guidance receptor 1
chr19_-_39738017 Show fit	0.69	ENST00000221804.5	CLC Ensembl NCBI GeneCards UniProt Show fit	Charcot-Leyden crystal galectin
chr16_+_3024000 Show fit	0.69	ENST00000326266.13 ENST00000574549.5 ENST00000575576.5 ENST00000253952.9	THOC6 Ensembl NCBI GeneCards UniProt Show fit	THO complex 6
chr17_-_46192767 Show fit	0.69	ENST00000262419.10	KANSL1 Ensembl NCBI GeneCards UniProt Show fit	KAT8 regulatory NSL complex subunit 1
chr10_+_100998348 Show fit	0.68	ENST00000429732.5	LZTS2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper tumor suppressor 2
chr15_+_43792305 Show fit	0.68	ENST00000249786.9 ENST00000409960.6 ENST00000409646.5 ENST00000339624.9 ENST00000409291.5 ENST00000402131.5 ENST00000403425.5 ENST00000430901.1	SERF2 Ensembl NCBI GeneCards UniProt Show fit	small EDRK-rich factor 2
chr19_-_51026593 Show fit	0.67	ENST00000600362.5 ENST00000453757.8 ENST00000601671.1	KLK11 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 11
chr7_+_77122609 Show fit	0.66	ENST00000285871.5	CCDC146 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 146
chr1_+_241652275 Show fit	0.66	ENST00000366552.6 ENST00000437684.7	WDR64 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 64
chr5_+_177303768 Show fit	0.66	ENST00000303204.9 ENST00000503216.5	PRELID1 Ensembl NCBI GeneCards UniProt Show fit	PRELI domain containing 1
chr17_+_28744002 Show fit	0.66	ENST00000618771.1 ENST00000262395.10 ENST00000422344.5	TRAF4 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr7_+_121328991 Show fit	0.66	ENST00000222462.3	WNT16 Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 16
chr17_-_3691748 Show fit	0.66	ENST00000552723.1	P2RX5 Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2X 5
chr22_-_16592810 Show fit	0.66	ENST00000359963.4	CCT8L2 Ensembl NCBI GeneCards UniProt Show fit	chaperonin containing TCP1 subunit 8 like 2
chr14_-_58427158 Show fit	0.65	ENST00000555097.1 ENST00000556367.6 ENST00000555404.5	TIMM9 Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 9
chr3_-_15333152 Show fit	0.65	ENST00000426925.5	SH3BP5 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding protein 5
chr15_-_31101707 Show fit	0.65	ENST00000397795.6 ENST00000256552.11 ENST00000559179.2	TRPM1 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily M member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.5	GO:0051598	meiotic recombination checkpoint(GO:0051598)
1.8	19.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
1.3	3.8	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.1	3.4	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
0.7	5.0	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6	1.8	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
0.4	1.3	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.4	1.7	GO:2001301	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.4	3.7	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4	1.1	GO:1904268	positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.4	1.5	GO:0009443	pyridoxal 5'-phosphate salvage(GO:0009443)
0.4	58.3	GO:0030449	regulation of complement activation(GO:0030449)
0.4	0.7	GO:0071623	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.3	1.7	GO:0035905	N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3	1.3	GO:0042335	cuticle development(GO:0042335)
0.3	1.2	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3	0.9	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3	2.6	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.3	0.9	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.3	1.1	GO:1903182	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.3	1.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.2	3.0	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.2	1.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	1.7	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2	1.2	GO:0001555	oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.2	0.9	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2	1.4	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2	0.8	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	1.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.2	0.7	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2	0.9	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2	2.9	GO:0048733	sebaceous gland development(GO:0048733)
0.2	0.8	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	4.5	GO:0001675	acrosome assembly(GO:0001675)
0.2	5.6	GO:0042832	defense response to protozoan(GO:0042832)
0.2	1.7	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	0.5	GO:0001827	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2	1.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2	3.6	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.9	GO:0021993	initiation of neural tube closure(GO:0021993)
0.1	1.8	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.1	0.4	GO:0035674	tricarboxylic acid transmembrane transport(GO:0035674)
0.1	2.3	GO:0007144	female meiosis I(GO:0007144)
0.1	0.7	GO:0018057	peptidyl-lysine oxidation(GO:0018057)
0.1	2.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.7	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	1.4	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.4	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	27.5	GO:0002377	immunoglobulin production(GO:0002377)
0.1	1.6	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	2.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.5	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.1	3.2	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.1	1.4	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	2.3	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.5	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.8	GO:0072138	mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1	0.7	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1	0.3	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	0.7	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.1	1.2	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.7	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	2.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.9	GO:0002467	germinal center formation(GO:0002467)
0.1	0.5	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.1	1.7	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	1.4	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1	0.3	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	0.3	GO:0090156	cellular sphingolipid homeostasis(GO:0090156)
0.1	2.3	GO:0042026	protein refolding(GO:0042026)
0.1	0.5	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	2.3	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.1	1.8	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	0.4	GO:0007296	vitellogenesis(GO:0007296)
0.1	2.4	GO:0019835	cytolysis(GO:0019835)
0.1	0.4	GO:0046061	dATP catabolic process(GO:0046061)
0.0	1.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.9	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.4	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.5	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.8	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	1.3	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.9	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	1.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	5.8	GO:0070268	cornification(GO:0070268)
0.0	1.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.6	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.8	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.4	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	1.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.3	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	2.4	GO:0030317	sperm motility(GO:0030317)
0.0	0.2	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.4	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.4	GO:0006477	protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	1.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.9	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.2	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0	0.1	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0	0.2	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.7	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.1	GO:0070845	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0	1.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.6	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	1.0	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0	0.3	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	2.9	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0	0.3	GO:0071321	cellular response to cGMP(GO:0071321)
0.0	0.7	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.0	4.2	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.4	GO:2000352	negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0	0.3	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	1.4	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0	1.6	GO:0016266	O-glycan processing(GO:0016266)
0.0	2.0	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	1.1	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	1.8	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.9	GO:0001881	receptor recycling(GO:0001881)
0.0	0.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.6	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	1.0	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	19.7	GO:0071750	dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.4	1.2	GO:0043159	acrosomal matrix(GO:0043159)
0.4	2.6	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4	2.8	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.3	16.8	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.3	1.1	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
0.2	1.7	GO:0001652	granular component(GO:0001652)
0.2	12.5	GO:0000795	synaptonemal complex(GO:0000795)
0.2	0.9	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2	7.3	GO:0002080	acrosomal membrane(GO:0002080)
0.1	0.6	GO:0035841	new growing cell tip(GO:0035841)
0.1	2.1	GO:0042788	polysomal ribosome(GO:0042788)
0.1	2.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	2.0	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.8	GO:0032280	symmetric synapse(GO:0032280)
0.1	2.3	GO:0000786	nucleosome(GO:0000786)
0.1	6.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.0	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.3	GO:0098855	HCN channel complex(GO:0098855)
0.1	0.4	GO:0043291	RAVE complex(GO:0043291)
0.1	1.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	1.0	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	0.8	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	5.0	GO:0045095	keratin filament(GO:0045095)
0.1	0.3	GO:0035339	SPOTS complex(GO:0035339)
0.1	0.5	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
0.0	1.5	GO:0001891	phagocytic cup(GO:0001891)
0.0	1.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.4	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	1.8	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.3	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	1.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	7.6	GO:0072562	blood microparticle(GO:0072562)
0.0	4.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	2.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.4	GO:0097255	R2TP complex(GO:0097255)
0.0	0.8	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.8	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	1.1	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	1.3	GO:0002102	podosome(GO:0002102)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	1.6	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	1.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.4	GO:0005861	troponin complex(GO:0005861)
0.0	3.9	GO:0031901	early endosome membrane(GO:0031901)
0.0	3.5	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	34.1	GO:0005615	extracellular space(GO:0005615)
0.0	3.6	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.8	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	3.6	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0045160	myosin I complex(GO:0045160)
0.0	0.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	1.8	GO:0016234	inclusion body(GO:0016234)
0.0	1.0	GO:0001772	immunological synapse(GO:0001772)
0.0	0.8	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
0.5	36.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.4	1.7	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.4	1.5	GO:0008478	pyridoxal kinase activity(GO:0008478)
0.3	3.4	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.3	1.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.3	70.2	GO:0003823	antigen binding(GO:0003823)
0.3	5.0	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3	1.2	GO:0004040	amidase activity(GO:0004040)
0.3	0.8	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3	1.1	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
0.3	3.4	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.2	3.7	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	0.5	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2	0.9	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	1.2	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	1.4	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.4	GO:0044713	GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.1	0.6	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	2.1	GO:0003796	lysozyme activity(GO:0003796)
0.1	1.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	1.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.8	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.8	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.7	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	1.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	3.0	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	0.2	GO:0070984	SET domain binding(GO:0070984)
0.1	1.4	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.7	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.8	GO:0000150	recombinase activity(GO:0000150)
0.1	0.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.7	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.5	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.7	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	3.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	2.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	2.1	GO:0000217	DNA secondary structure binding(GO:0000217)
0.1	0.7	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.7	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	0.4	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	2.6	GO:0005109	frizzled binding(GO:0005109)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.4	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	1.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.2	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.0	0.4	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.3	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	1.0	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.6	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	6.5	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.9	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	1.1	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004905	type I interferon receptor activity(GO:0004905)
0.0	1.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.8	GO:0048156	tau protein binding(GO:0048156)
0.0	0.4	GO:0031014	troponin T binding(GO:0031014)
0.0	0.8	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	1.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	1.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.6	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	1.7	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	5.6	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.7	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0052856	NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0	2.0	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	4.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	1.1	GO:0004601	peroxidase activity(GO:0004601)
0.0	1.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	1.4	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.8	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	3.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	1.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	2.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	1.9	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.8	PID ATM PATHWAY	ATM pathway
0.1	1.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.9	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	3.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	10.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	4.4	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	2.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID SHP2 PATHWAY	SHP2 signaling
0.0	1.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	1.2	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.4	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	2.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	3.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	3.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	3.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	0.9	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	1.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	2.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	5.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.8	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	3.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	2.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.7	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	2.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.6	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing

Results for THRA_RXRB

Z-value: 2.43

Motif logo

Transcription factors associated with THRA_RXRB

Activity-expression correlation:

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: