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avrg: Illumina Body Map 2 (GSE30611)
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Results for TWIST1_SNAI1
Z-value: 2.77
Motif logo
Transcription factors associated with TWIST1_SNAI1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TWIST1
|
ENSG00000122691.13 | TWIST1 |
|
SNAI1
|
ENSG00000124216.4 | SNAI1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SNAI1 | hg38_v1_chr20_+_49982969_49982989 | 0.28 | 1.2e-01 | Click! |
| TWIST1 | hg38_v1_chr7_-_19117625_19117645 | 0.09 | 6.3e-01 | Click! |
Activity profile of TWIST1_SNAI1 motif
Sorted Z-values of TWIST1_SNAI1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of TWIST1_SNAI1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 15.0 | GO:0043000 | Golgi to plasma membrane CFTR protein transport(GO:0043000) |
| 4.7 | 14.1 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 2.4 | 9.5 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 1.7 | 6.8 | GO:0097195 | pilomotor reflex(GO:0097195) |
| 1.6 | 6.4 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 1.6 | 6.3 | GO:0048627 | myoblast development(GO:0048627) |
| 1.4 | 5.6 | GO:0003165 | Purkinje myocyte development(GO:0003165) |
| 1.4 | 10.9 | GO:0044332 | Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) |
| 1.3 | 6.5 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 1.1 | 3.4 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.1 | 4.5 | GO:0060621 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
| 1.1 | 8.7 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 1.1 | 7.4 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 0.9 | 2.6 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.8 | 3.2 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.8 | 3.2 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.8 | 6.4 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
| 0.8 | 1.6 | GO:0044752 | response to human chorionic gonadotropin(GO:0044752) |
| 0.7 | 2.2 | GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth(GO:0042489) |
| 0.7 | 2.9 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.7 | 11.5 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.7 | 2.1 | GO:0009386 | translational attenuation(GO:0009386) |
| 0.7 | 4.0 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.7 | 4.6 | GO:0032439 | endosome localization(GO:0032439) |
| 0.6 | 2.5 | GO:0032599 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 0.6 | 6.8 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.6 | 3.1 | GO:0060327 | cytoplasmic actin-based contraction involved in cell motility(GO:0060327) |
| 0.6 | 2.4 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.6 | 1.7 | GO:0061713 | neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) |
| 0.6 | 1.7 | GO:0052314 | phytoalexin metabolic process(GO:0052314) |
| 0.6 | 4.0 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.6 | 8.4 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.6 | 3.3 | GO:1904219 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.6 | 3.3 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.6 | 1.7 | GO:1902910 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 0.5 | 3.8 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.5 | 21.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.5 | 2.6 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.5 | 2.1 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.5 | 1.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.5 | 1.5 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 0.5 | 17.1 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.5 | 1.9 | GO:0042377 | menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377) |
| 0.5 | 4.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.5 | 7.9 | GO:0015871 | choline transport(GO:0015871) |
| 0.5 | 1.8 | GO:0031456 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.5 | 1.8 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.4 | 4.5 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.4 | 2.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.4 | 3.1 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 0.4 | 1.8 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.4 | 2.1 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.4 | 1.7 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.4 | 0.4 | GO:0090381 | regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) |
| 0.4 | 6.1 | GO:0002934 | desmosome organization(GO:0002934) |
| 0.4 | 1.6 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 0.4 | 6.9 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.4 | 1.5 | GO:1902161 | positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 0.4 | 1.9 | GO:0035645 | enteric smooth muscle cell differentiation(GO:0035645) |
| 0.4 | 9.8 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.4 | 1.1 | GO:0007315 | oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719) |
| 0.4 | 2.9 | GO:1903382 | neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382) |
| 0.4 | 3.6 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.4 | 1.1 | GO:0034445 | regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 0.4 | 1.1 | GO:0060623 | regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283) |
| 0.4 | 2.1 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.3 | 5.0 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.3 | 1.0 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673) |
| 0.3 | 3.6 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.3 | 1.0 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.3 | 0.7 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.3 | 4.2 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.3 | 1.6 | GO:0030070 | insulin processing(GO:0030070) |
| 0.3 | 5.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.3 | 5.1 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 0.3 | 1.9 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 0.3 | 0.9 | GO:0006147 | guanine catabolic process(GO:0006147) |
| 0.3 | 0.9 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.3 | 1.2 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.3 | 0.9 | GO:0038162 | erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662) |
| 0.3 | 1.2 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) |
| 0.3 | 3.7 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.3 | 1.7 | GO:0070378 | positive regulation of ERK5 cascade(GO:0070378) |
| 0.3 | 0.9 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.3 | 1.1 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
| 0.3 | 0.8 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.3 | 1.9 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 3.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.3 | 1.1 | GO:0006175 | adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) |
| 0.3 | 0.3 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 0.3 | 3.3 | GO:0015705 | iodide transport(GO:0015705) |
| 0.2 | 1.0 | GO:0044691 | tooth eruption(GO:0044691) |
| 0.2 | 3.2 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 3.0 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 1.5 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.2 | 0.5 | GO:0060003 | copper ion export(GO:0060003) |
| 0.2 | 0.7 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 0.2 | 1.6 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.2 | 2.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.2 | 1.4 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.2 | 1.0 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.2 | 0.4 | GO:1902908 | regulation of melanosome transport(GO:1902908) |
| 0.2 | 1.2 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.2 | 4.3 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.2 | 1.7 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.2 | 1.5 | GO:0021592 | fourth ventricle development(GO:0021592) |
| 0.2 | 2.3 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.2 | 1.1 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.2 | 0.7 | GO:2000724 | mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724) |
| 0.2 | 0.5 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.2 | 0.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.2 | 0.5 | GO:0050955 | thermoception(GO:0050955) |
| 0.2 | 3.7 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.9 | GO:0046963 | 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559) |
| 0.2 | 0.7 | GO:0072134 | nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069) |
| 0.2 | 1.6 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.2 | 1.2 | GO:1903412 | response to bile acid(GO:1903412) |
| 0.2 | 0.7 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.2 | 0.3 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 0.2 | 2.5 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.2 | 0.2 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.2 | 1.9 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.2 | 0.8 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.2 | 2.6 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.2 | 1.1 | GO:0071104 | negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) |
| 0.1 | 1.0 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.1 | 1.5 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.1 | 5.2 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.4 | GO:0060032 | notochord regression(GO:0060032) |
| 0.1 | 0.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 3.8 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.6 | GO:1903892 | negative regulation of ATF6-mediated unfolded protein response(GO:1903892) |
| 0.1 | 0.6 | GO:0021634 | optic nerve formation(GO:0021634) pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) optic chiasma development(GO:0061360) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597) |
| 0.1 | 1.1 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
| 0.1 | 0.4 | GO:1902338 | negative regulation of apoptotic process involved in morphogenesis(GO:1902338) negative regulation of apoptotic process involved in development(GO:1904746) |
| 0.1 | 0.7 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.1 | 1.5 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 0.1 | 0.8 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.1 | 3.6 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.1 | 1.9 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 1.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 1.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 1.6 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.1 | 0.5 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983) |
| 0.1 | 0.9 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 0.1 | 0.4 | GO:1903597 | negative regulation of gap junction assembly(GO:1903597) |
| 0.1 | 9.1 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 5.2 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.1 | 1.9 | GO:0016264 | gap junction assembly(GO:0016264) |
| 0.1 | 2.4 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 1.4 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
| 0.1 | 3.8 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.1 | 0.4 | GO:0060266 | negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) neuron projection maintenance(GO:1990535) |
| 0.1 | 0.4 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.1 | 0.4 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 0.1 | 2.4 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.1 | 0.2 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) |
| 0.1 | 2.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.6 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.1 | 2.6 | GO:0036159 | outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159) |
| 0.1 | 0.3 | GO:2001311 | lysobisphosphatidic acid metabolic process(GO:2001311) |
| 0.1 | 0.7 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.1 | 2.3 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.1 | 0.7 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.1 | 1.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.1 | 0.7 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.1 | 11.5 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.1 | 0.1 | GO:2000667 | positive regulation of interleukin-13 secretion(GO:2000667) |
| 0.1 | 6.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 0.5 | GO:1990426 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) homologous recombination-dependent replication fork processing(GO:1990426) |
| 0.1 | 2.4 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.1 | 0.6 | GO:0002803 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
| 0.1 | 1.4 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.1 | 0.9 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 1.5 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.1 | 0.5 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.1 | 0.7 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.1 | 2.6 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 2.7 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 5.8 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.1 | 1.3 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 0.1 | 3.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 2.8 | GO:0048385 | regulation of retinoic acid receptor signaling pathway(GO:0048385) |
| 0.1 | 0.4 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 0.8 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 1.5 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 0.9 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.1 | 0.8 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.1 | 3.7 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 2.8 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.1 | 1.9 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.1 | 3.3 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.1 | 0.7 | GO:0045836 | positive regulation of meiotic nuclear division(GO:0045836) |
| 0.1 | 0.4 | GO:1901545 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.1 | 2.0 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.1 | 0.3 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.1 | 0.2 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
| 0.1 | 1.6 | GO:0048569 | post-embryonic organ development(GO:0048569) |
| 0.1 | 1.1 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.1 | 0.6 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 2.0 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.1 | 0.4 | GO:0006565 | L-serine catabolic process(GO:0006565) |
| 0.1 | 1.9 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.1 | 1.6 | GO:0035810 | positive regulation of urine volume(GO:0035810) |
| 0.1 | 0.2 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.1 | 0.4 | GO:0009440 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.1 | 0.2 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.1 | 1.4 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.1 | 2.4 | GO:0001556 | oocyte maturation(GO:0001556) |
| 0.1 | 2.0 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 0.3 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.1 | 1.1 | GO:2001016 | positive regulation of skeletal muscle cell differentiation(GO:2001016) |
| 0.1 | 1.0 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 0.3 | GO:0034241 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.1 | 0.9 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.1 | 0.8 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.1 | 1.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 1.2 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.1 | 1.9 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 0.6 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 1.6 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.1 | 1.1 | GO:0060732 | regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 6.5 | GO:0007588 | excretion(GO:0007588) |
| 0.1 | 0.4 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
| 0.1 | 0.9 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 1.3 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.1 | 0.6 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.1 | 0.4 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.1 | 1.2 | GO:0046500 | S-adenosylmethionine metabolic process(GO:0046500) |
| 0.1 | 0.4 | GO:1905123 | regulation of glucosylceramidase activity(GO:1905123) |
| 0.1 | 0.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 2.2 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.1 | 1.2 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 1.4 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 0.8 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.1 | 2.0 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.1 | 0.7 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.1 | 0.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.1 | 0.4 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 0.1 | 0.6 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
| 0.1 | 0.6 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 1.7 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 0.2 | GO:0060023 | soft palate development(GO:0060023) |
| 0.0 | 0.2 | GO:0036116 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.0 | 0.4 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.0 | 0.6 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 1.1 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.0 | 0.7 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
| 0.0 | 4.8 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.8 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.6 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.0 | 0.9 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 0.5 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 1.7 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.9 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.2 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.0 | 0.2 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.0 | 1.2 | GO:0060412 | ventricular septum morphogenesis(GO:0060412) |
| 0.0 | 0.0 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.0 | 1.0 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 1.3 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 1.3 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.0 | 0.2 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 0.0 | 0.3 | GO:2000535 | glycoside catabolic process(GO:0016139) regulation of entry of bacterium into host cell(GO:2000535) |
| 0.0 | 0.2 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 0.0 | 0.2 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 0.0 | 0.1 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.0 | 0.7 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 1.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 2.4 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.0 | 0.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 0.2 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.0 | 0.1 | GO:0050428 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.0 | 0.2 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
| 0.0 | 1.4 | GO:0090004 | positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.0 | 2.9 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.6 | GO:0048265 | response to pain(GO:0048265) |
| 0.0 | 1.3 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 2.7 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
| 0.0 | 2.5 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 0.4 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.5 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.0 | 0.2 | GO:0016321 | female meiosis chromosome segregation(GO:0016321) |
| 0.0 | 0.4 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.3 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.0 | 0.1 | GO:0070781 | protein biotinylation(GO:0009305) response to biotin(GO:0070781) histone biotinylation(GO:0071110) |
| 0.0 | 0.7 | GO:0035729 | cellular response to hepatocyte growth factor stimulus(GO:0035729) |
| 0.0 | 0.2 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.0 | 6.4 | GO:0031424 | keratinization(GO:0031424) |
| 0.0 | 0.6 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.0 | 0.1 | GO:0046959 | habituation(GO:0046959) |
| 0.0 | 0.9 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
| 0.0 | 0.5 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 0.4 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.0 | 0.5 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.1 | GO:0060319 | primitive erythrocyte differentiation(GO:0060319) |
| 0.0 | 0.6 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.0 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.0 | 3.6 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 1.0 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.8 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.0 | 0.8 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.1 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.2 | GO:0060452 | positive regulation of cardiac muscle contraction(GO:0060452) |
| 0.0 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 1.0 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
| 0.0 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 2.1 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
| 0.0 | 2.4 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.0 | 0.4 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.3 | GO:0060896 | neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897) |
| 0.0 | 0.9 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.0 | 0.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 0.4 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 0.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.2 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.0 | 0.5 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.0 | 0.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.0 | 0.8 | GO:0015879 | quaternary ammonium group transport(GO:0015697) amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879) |
| 0.0 | 0.0 | GO:0003223 | ventricular compact myocardium morphogenesis(GO:0003223) |
| 0.0 | 0.1 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.0 | 0.1 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.0 | 0.7 | GO:0090383 | ATP hydrolysis coupled proton transport(GO:0015991) phagosome acidification(GO:0090383) |
| 0.0 | 0.0 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 0.0 | 1.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.1 | GO:0046901 | tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901) |
| 0.0 | 0.7 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.0 | 0.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 1.2 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.0 | GO:0030432 | peristalsis(GO:0030432) |
| 0.0 | 0.2 | GO:1990592 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.0 | 0.2 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.2 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.5 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.0 | 0.1 | GO:1990697 | protein depalmitoleylation(GO:1990697) |
| 0.0 | 1.1 | GO:0042446 | hormone biosynthetic process(GO:0042446) |
| 0.0 | 0.2 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.0 | 0.1 | GO:1905247 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.0 | 0.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.0 | 0.7 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 0.1 | GO:0090598 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 0.0 | 0.8 | GO:0001658 | branching involved in ureteric bud morphogenesis(GO:0001658) |
| 0.0 | 0.2 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.0 | 0.2 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.0 | 0.3 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.7 | GO:0007140 | male meiosis(GO:0007140) |
| 0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 0.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 0.9 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 1.9 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.0 | 0.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.5 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.0 | 0.4 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.0 | 0.2 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.0 | 0.4 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.0 | 0.5 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 1.0 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.1 | GO:0042226 | interleukin-6 biosynthetic process(GO:0042226) |
| 0.0 | 0.2 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.0 | 0.2 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.0 | 0.4 | GO:0097435 | fibril organization(GO:0097435) |
| 0.0 | 0.2 | GO:0040018 | positive regulation of multicellular organism growth(GO:0040018) |
| 0.0 | 0.3 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.8 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 0.1 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.0 | 0.1 | GO:0055129 | L-proline biosynthetic process(GO:0055129) |
| 0.0 | 1.1 | GO:0002793 | positive regulation of peptide secretion(GO:0002793) positive regulation of peptide hormone secretion(GO:0090277) |
| 0.0 | 0.4 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 0.1 | GO:1902572 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 0.0 | 0.2 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.0 | 0.1 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 0.0 | 0.1 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.0 | 0.1 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 0.1 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.0 | 0.5 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.0 | 1.3 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.1 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 7.5 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 1.0 | 6.8 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.8 | 9.8 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.7 | 5.7 | GO:0070695 | FHF complex(GO:0070695) |
| 0.7 | 5.5 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.6 | 1.9 | GO:0043259 | laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 0.6 | 1.1 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.5 | 1.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.5 | 19.9 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.4 | 1.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 4.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.4 | 12.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.4 | 1.6 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
| 0.4 | 2.7 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.4 | 7.5 | GO:0045179 | apical cortex(GO:0045179) |
| 0.4 | 18.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.4 | 3.6 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.4 | 13.3 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 1.0 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.3 | 5.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.3 | 0.8 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.3 | 5.0 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.3 | 9.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.3 | 1.1 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 0.3 | 1.5 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.2 | 0.7 | GO:0000229 | cytoplasmic chromosome(GO:0000229) |
| 0.2 | 0.7 | GO:0030849 | autosome(GO:0030849) |
| 0.2 | 5.8 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.2 | 2.4 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 0.9 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.2 | 2.6 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.2 | 0.6 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.2 | 4.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.2 | 1.9 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 4.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 2.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 2.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 11.4 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 13.8 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 5.9 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 1.1 | GO:0071546 | pi-body(GO:0071546) |
| 0.1 | 0.7 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.1 | 0.5 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.7 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.1 | 1.6 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 0.7 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.1 | 3.1 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.4 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 2.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 24.8 | GO:0070160 | occluding junction(GO:0070160) |
| 0.1 | 1.2 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.4 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 0.3 | GO:1990038 | glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038) |
| 0.1 | 1.3 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 21.8 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 0.6 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.1 | 1.1 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 14.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 3.1 | GO:0034706 | sodium channel complex(GO:0034706) |
| 0.1 | 9.8 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.4 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.1 | 1.0 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.9 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 0.8 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 0.2 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 0.1 | 2.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 2.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 1.0 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 0.6 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.1 | 1.1 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.1 | 0.9 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 4.8 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.1 | 0.2 | GO:0030689 | Noc complex(GO:0030689) |
| 0.1 | 29.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 0.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 0.6 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 5.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 2.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.2 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.0 | 0.1 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 0.0 | 5.3 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 0.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 6.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 3.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 1.1 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 1.1 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.3 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 8.3 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 2.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 2.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.5 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.5 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 8.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 0.6 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 0.1 | GO:1990742 | microvesicle(GO:1990742) |
| 0.0 | 0.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 2.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.2 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.0 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 1.7 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.1 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 2.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 4.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
| 0.0 | 0.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.1 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 1.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 3.9 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.0 | GO:0043195 | terminal bouton(GO:0043195) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 7.5 | GO:1904928 | coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928) |
| 1.9 | 5.7 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 1.3 | 6.5 | GO:0033906 | hyaluronoglucuronidase activity(GO:0033906) |
| 1.3 | 3.8 | GO:0019785 | ISG15-specific protease activity(GO:0019785) |
| 1.0 | 2.9 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.9 | 3.7 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.9 | 8.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.9 | 4.5 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.8 | 3.2 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.8 | 8.0 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.7 | 15.1 | GO:0008430 | selenium binding(GO:0008430) |
| 0.7 | 2.8 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.7 | 2.7 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.7 | 29.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.6 | 12.3 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.6 | 1.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.5 | 3.3 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.5 | 17.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.5 | 3.6 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.4 | 1.7 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.4 | 1.6 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.4 | 6.9 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.4 | 1.2 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.4 | 1.5 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.4 | 3.4 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.4 | 1.9 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.4 | 1.5 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
| 0.4 | 2.6 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.4 | 7.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.3 | 1.4 | GO:0004040 | amidase activity(GO:0004040) |
| 0.3 | 2.0 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 2.6 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.3 | 0.9 | GO:0008892 | guanine deaminase activity(GO:0008892) |
| 0.3 | 0.9 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990) |
| 0.3 | 1.2 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 0.3 | 2.4 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.3 | 1.9 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.3 | 9.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.3 | 2.1 | GO:0035473 | lipase binding(GO:0035473) |
| 0.3 | 1.1 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 0.2 | 1.7 | GO:0030298 | receptor signaling protein tyrosine kinase activator activity(GO:0030298) |
| 0.2 | 5.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 1.2 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.2 | 1.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.2 | 2.5 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.2 | 1.1 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.2 | 0.7 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.2 | 2.2 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.2 | 1.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.2 | 2.8 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.2 | 1.7 | GO:0015199 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 0.2 | 0.6 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.2 | 1.0 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 3.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.2 | 0.8 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.2 | 2.3 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.2 | 1.9 | GO:0046870 | cadmium ion binding(GO:0046870) |
| 0.2 | 1.1 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.2 | 2.7 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 1.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.2 | 0.9 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.2 | 2.3 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.2 | 2.1 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.2 | 0.7 | GO:0031751 | D4 dopamine receptor binding(GO:0031751) |
| 0.2 | 4.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.2 | 2.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.2 | 2.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 3.5 | GO:0019841 | retinol binding(GO:0019841) |
| 0.2 | 3.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.2 | 1.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.2 | 0.5 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 0.2 | 3.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 7.6 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.1 | 2.7 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.1 | 2.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.1 | 0.6 | GO:0072591 | citrate-L-glutamate ligase activity(GO:0072591) |
| 0.1 | 1.9 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.1 | 1.6 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 1.7 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 1.7 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 1.0 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.1 | 0.4 | GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842) |
| 0.1 | 3.0 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 1.2 | GO:0005497 | androgen binding(GO:0005497) |
| 0.1 | 0.5 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.1 | 19.2 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.1 | 4.6 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.4 | GO:0072545 | tyrosine binding(GO:0072545) |
| 0.1 | 3.9 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.4 | GO:0008520 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.1 | 0.5 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.1 | 1.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 6.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 3.9 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 0.9 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.1 | 2.6 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.1 | 0.4 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 0.1 | 2.2 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 0.6 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 0.3 | GO:0052642 | lysophosphatidic acid phosphatase activity(GO:0052642) |
| 0.1 | 1.4 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.5 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 0.1 | 0.3 | GO:0004314 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.1 | 0.7 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.1 | 0.8 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 0.6 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.1 | 1.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 3.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 4.6 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 2.9 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.1 | 2.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.6 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.1 | 0.4 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.1 | 2.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.3 | GO:0047025 | 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025) |
| 0.1 | 0.4 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.1 | 1.2 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 0.4 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.1 | 0.4 | GO:0070025 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 0.1 | 1.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 0.8 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.1 | 0.9 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 1.0 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.3 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 0.1 | 2.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 0.7 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.1 | 1.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 0.2 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.1 | 0.8 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 0.3 | GO:0004335 | galactokinase activity(GO:0004335) |
| 0.1 | 1.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 1.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 2.9 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 7.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 7.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 3.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 0.8 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.1 | 0.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 5.9 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 0.4 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.1 | 0.6 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.7 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 0.5 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.1 | 1.8 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 2.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.4 | GO:0008241 | tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) |
| 0.1 | 0.5 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 0.8 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 0.5 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.1 | 0.4 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.1 | 1.0 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.9 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 0.7 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.1 | 2.6 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.1 | 0.8 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.1 | 0.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 1.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 2.3 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.2 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.1 | 2.3 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 0.9 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 1.1 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.1 | 0.9 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 0.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.4 | GO:0004144 | diacylglycerol O-acyltransferase activity(GO:0004144) |
| 0.1 | 1.6 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 1.1 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.6 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 1.8 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.0 | 1.0 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.0 | 0.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.0 | 0.9 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 4.9 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 0.0 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.1 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.4 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 1.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.9 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.2 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.0 | 0.1 | GO:0052856 | NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857) |
| 0.0 | 0.3 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.0 | 2.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.0 | 1.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.3 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.8 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.0 | 1.0 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 0.1 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.0 | 0.2 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 1.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 2.8 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.2 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.0 | 3.8 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.5 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.0 | 6.0 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.9 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 1.7 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.0 | 0.5 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 4.1 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.1 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.0 | 0.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.0 | 0.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 1.2 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.1 | GO:0005113 | patched binding(GO:0005113) |
| 0.0 | 0.4 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 0.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 2.1 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.1 | GO:0031531 | thyrotropin-releasing hormone receptor binding(GO:0031531) |
| 0.0 | 1.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.1 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
| 0.0 | 0.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.6 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.0 | 0.1 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
| 0.0 | 0.1 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.0 | 0.1 | GO:1990699 | palmitoleyl hydrolase activity(GO:1990699) |
| 0.0 | 0.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 0.8 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
| 0.0 | 1.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.1 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.0 | 0.4 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.9 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 1.9 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.0 | 0.3 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 1.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 0.4 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.9 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.5 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.3 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 0.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.0 | 1.0 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 2.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.1 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.0 | 2.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.2 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 0.0 | 0.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.1 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.0 | 0.1 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.1 | GO:0044020 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.0 | 0.2 | GO:0008061 | chitin binding(GO:0008061) |
| 0.0 | 0.2 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.1 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 0.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.0 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.0 | 0.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.1 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 1.0 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.3 | 9.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 16.5 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.2 | 9.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 7.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 10.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 3.5 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 1.1 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 12.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 8.0 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.1 | 4.0 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 1.9 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 0.6 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 3.5 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 1.2 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 3.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 2.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.8 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 10.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.6 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.6 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 1.0 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.5 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 2.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 3.6 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.1 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.9 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.4 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.3 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.9 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.2 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 1.1 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.5 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 3.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 3.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 10.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.7 | 32.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.5 | 12.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.5 | 2.6 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.5 | 13.1 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.3 | 7.3 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.3 | 4.7 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 6.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 2.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.2 | 4.0 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.2 | 5.5 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 0.7 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.2 | 10.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 5.3 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 7.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.2 | 3.8 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 1.8 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 7.1 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 0.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 9.7 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 3.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 2.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 3.2 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 2.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 3.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 4.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.6 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 1.4 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 2.2 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 1.1 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.1 | 2.0 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 3.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 2.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 6.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.8 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 2.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 1.2 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.1 | 3.1 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 2.6 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 2.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.0 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.9 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 1.8 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 9.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 1.6 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 1.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.8 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 1.6 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.0 | 1.3 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.2 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 0.7 | REACTOME SHC MEDIATED CASCADE | Genes involved in SHC-mediated cascade |
| 0.0 | 2.5 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.6 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.5 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.9 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.6 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 2.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 1.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.2 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.8 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.7 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.0 | 0.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.7 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 1.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 3.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.4 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.9 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 0.2 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.7 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.4 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.8 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.4 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.1 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 1.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.3 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |