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avrg: Illumina Body Map 2 (GSE30611)

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Results for VENTX

Z-value: 1.64

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Transcription factors associated with VENTX

Gene Symbol Gene ID Gene Info
VENTX
ENSG00000151650.8 VENTX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VENTXhg38_v1_chr10_+_133237849_1332378630.192.9e-01Click!

Activity profile of VENTX motif

Sorted Z-values of VENTX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VENTX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_154590735 4.71 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr12_+_107318395 3.32 ENST00000420571.6
ENST00000280758.10
BTBD11
BTB domain containing 11
chr18_+_31591869 3.25 ENST00000237014.8
TTR
transthyretin
chr3_+_186666003 2.36 ENST00000232003.5
HRG
histidine rich glycoprotein
chr16_-_51151259 2.28 ENST00000251020.9
SALL1
spalt like transcription factor 1
chr2_+_134838610 2.23 ENST00000356140.10
ENST00000392928.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr17_+_46624036 1.99 ENST00000575068.5
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr14_+_21965451 1.96 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr14_+_92323154 1.95 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
SLC24A4
solute carrier family 24 member 4
chr8_+_49911604 1.81 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
SNTG1
syntrophin gamma 1
chr5_+_142874881 1.78 ENST00000475287.2
ARHGAP26
Rho GTPase activating protein 26
chr11_+_123560240 1.76 ENST00000529432.5
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr16_-_51151238 1.65 ENST00000566102.1
SALL1
spalt like transcription factor 1
chr18_+_61333424 1.59 ENST00000262717.9
CDH20
cadherin 20
chrX_+_78747705 1.51 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
LPAR4
lysophosphatidic acid receptor 4
chr3_+_32817990 1.51 ENST00000383763.6
TRIM71
tripartite motif containing 71
chr12_+_111034136 1.50 ENST00000261726.11
CUX2
cut like homeobox 2
chr7_+_54542300 1.45 ENST00000302287.7
ENST00000407838.7
VSTM2A
V-set and transmembrane domain containing 2A
chr8_+_91249307 1.40 ENST00000309536.6
ENST00000276609.8
SLC26A7
solute carrier family 26 member 7
chr17_-_31318818 1.35 ENST00000578584.5
ENSG00000265118.5
novel protein
chrX_+_136648138 1.34 ENST00000370629.7
CD40LG
CD40 ligand
chr11_+_22338333 1.34 ENST00000263160.4
SLC17A6
solute carrier family 17 member 6
chr3_+_134795248 1.34 ENST00000398015.8
EPHB1
EPH receptor B1
chr7_+_54542362 1.32 ENST00000402613.4
VSTM2A
V-set and transmembrane domain containing 2A
chr12_-_119804298 1.29 ENST00000678652.1
ENST00000678494.1
CIT
citron rho-interacting serine/threonine kinase
chrX_+_106920393 1.28 ENST00000336803.2
CLDN2
claudin 2
chr2_+_86907953 1.25 ENST00000409776.6
RGPD1
RANBP2 like and GRIP domain containing 1
chr12_-_119803383 1.24 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chr16_+_70173783 1.21 ENST00000541793.7
ENST00000314151.12
ENST00000565806.5
ENST00000569347.6
ENST00000536907.2
CLEC18C
C-type lectin domain family 18 member C
chr7_+_54542393 1.18 ENST00000404951.5
VSTM2A
V-set and transmembrane domain containing 2A
chr17_+_70104848 1.14 ENST00000392670.5
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr6_+_77653035 1.13 ENST00000684080.1
MEI4
meiotic double-stranded break formation protein 4
chr7_-_83162899 1.13 ENST00000423517.6
PCLO
piccolo presynaptic cytomatrix protein
chr8_+_49911396 1.08 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr16_-_74421392 1.08 ENST00000339953.9
ENST00000620745.1
ENST00000682950.1
CLEC18B
C-type lectin domain family 18 member B
chr17_+_70104991 1.07 ENST00000587698.5
ENST00000587892.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chrX_+_131058340 1.07 ENST00000276211.10
ENST00000370922.5
ARHGAP36
Rho GTPase activating protein 36
chr2_+_170178136 1.05 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr3_+_134795277 1.05 ENST00000647596.1
EPHB1
EPH receptor B1
chr1_+_40247926 1.04 ENST00000372766.4
TMCO2
transmembrane and coiled-coil domains 2
chr14_+_64704380 1.03 ENST00000247226.13
ENST00000394691.7
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr10_-_72954790 1.01 ENST00000373032.4
PLA2G12B
phospholipase A2 group XIIB
chr4_-_46124046 1.01 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr7_-_108240049 0.99 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr15_+_33968484 0.98 ENST00000383263.7
CHRM5
cholinergic receptor muscarinic 5
chr16_-_67483541 0.98 ENST00000290953.3
AGRP
agouti related neuropeptide
chrX_+_106693838 0.96 ENST00000324342.7
RNF128
ring finger protein 128
chr12_+_69825221 0.96 ENST00000552032.7
MYRFL
myelin regulatory factor like
chrX_+_136648214 0.96 ENST00000370628.2
CD40LG
CD40 ligand
chr14_+_32329341 0.95 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
AKAP6
A-kinase anchoring protein 6
chr9_-_23826231 0.94 ENST00000397312.7
ELAVL2
ELAV like RNA binding protein 2
chr16_+_69951180 0.94 ENST00000288040.10
ENST00000449317.6
CLEC18A
C-type lectin domain family 18 member A
chr4_-_175812236 0.91 ENST00000505375.5
GPM6A
glycoprotein M6A
chr10_+_66926028 0.90 ENST00000361320.5
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr2_-_165203870 0.89 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr14_+_22202561 0.87 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr3_-_27722699 0.87 ENST00000461503.2
EOMES
eomesodermin
chr16_+_69950907 0.86 ENST00000393701.6
ENST00000568461.5
CLEC18A
C-type lectin domain family 18 member A
chr1_-_101846957 0.85 ENST00000338858.9
OLFM3
olfactomedin 3
chr19_-_45584810 0.85 ENST00000323060.3
OPA3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr1_-_114153863 0.82 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
SYT6
synaptotagmin 6
chrX_-_21658324 0.82 ENST00000379499.3
KLHL34
kelch like family member 34
chr10_-_60572599 0.82 ENST00000503366.5
ANK3
ankyrin 3
chr1_+_240123148 0.81 ENST00000681824.1
FMN2
formin 2
chr11_-_16356538 0.80 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr12_-_44875468 0.78 ENST00000553120.1
NELL2
neural EGFL like 2
chr6_+_37929959 0.78 ENST00000373389.5
ZFAND3
zinc finger AN1-type containing 3
chr9_+_79572572 0.77 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE4
TLE family member 4, transcriptional corepressor
chr12_+_69825273 0.76 ENST00000547771.6
MYRFL
myelin regulatory factor like
chr12_+_48328980 0.76 ENST00000335017.1
H1-7
H1.7 linker histone
chr1_+_240123121 0.75 ENST00000681210.1
FMN2
formin 2
chr10_-_25062279 0.75 ENST00000615958.4
ENKUR
enkurin, TRPC channel interacting protein
chr14_+_21841182 0.73 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr11_+_26473900 0.72 ENST00000531568.1
ANO3
anoctamin 3
chr14_+_64715677 0.71 ENST00000634379.2
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr17_-_40772162 0.71 ENST00000335552.4
KRT26
keratin 26
chr14_+_32329256 0.71 ENST00000280979.9
AKAP6
A-kinase anchoring protein 6
chr8_+_31639222 0.71 ENST00000519301.6
ENST00000652698.1
NRG1
neuregulin 1
chr13_+_108629605 0.70 ENST00000457511.7
MYO16
myosin XVI
chr13_+_75804270 0.70 ENST00000447038.5
LMO7
LIM domain 7
chr8_+_31639291 0.69 ENST00000651149.1
ENST00000650866.1
NRG1
neuregulin 1
chr13_+_75804169 0.69 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr12_+_25052220 0.67 ENST00000550945.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr5_-_124745315 0.67 ENST00000306315.9
ZNF608
zinc finger protein 608
chr2_-_178804623 0.66 ENST00000359218.10
ENST00000342175.11
TTN
titin
chr12_+_8513499 0.66 ENST00000299665.3
CLEC4D
C-type lectin domain family 4 member D
chr6_-_32668368 0.65 ENST00000399084.5
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr5_-_157059109 0.64 ENST00000523175.6
ENST00000522693.5
HAVCR1
hepatitis A virus cellular receptor 1
chr12_+_80716906 0.64 ENST00000228644.4
MYF5
myogenic factor 5
chr17_+_45161864 0.62 ENST00000589230.6
ENST00000591576.5
ENST00000591070.6
ENST00000592695.1
HEXIM2
HEXIM P-TEFb complex subunit 2
chr20_-_52105644 0.62 ENST00000371523.8
ZFP64
ZFP64 zinc finger protein
chr4_+_85827745 0.61 ENST00000509300.5
ARHGAP24
Rho GTPase activating protein 24
chr2_+_232520384 0.61 ENST00000617714.2
PRSS56
serine protease 56
chr12_+_25052512 0.60 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr5_+_65926644 0.59 ENST00000511297.5
ENST00000506030.5
ERBIN
erbb2 interacting protein
chr7_-_105269007 0.59 ENST00000357311.7
SRPK2
SRSF protein kinase 2
chr13_-_26221703 0.58 ENST00000381570.7
ENST00000346166.7
RNF6
ring finger protein 6
chr10_+_112283399 0.57 ENST00000643850.1
ENST00000646139.2
ENST00000645243.1
TECTB
tectorin beta
chr19_-_45584769 0.57 ENST00000263275.5
OPA3
outer mitochondrial membrane lipid metabolism regulator OPA3
chrM_+_3298 0.55 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
chr4_+_129096144 0.55 ENST00000425929.6
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr18_+_78979811 0.54 ENST00000537592.7
SALL3
spalt like transcription factor 3
chr8_-_42501224 0.54 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chrX_-_140505058 0.53 ENST00000370536.5
SOX3
SRY-box transcription factor 3
chr22_-_40533808 0.53 ENST00000422851.1
ENST00000651694.1
ENST00000652095.2
MRTFA
myocardin related transcription factor A
chr12_-_86256299 0.53 ENST00000552808.6
ENST00000547225.5
MGAT4C
MGAT4 family member C
chr5_-_131165231 0.52 ENST00000675100.1
ENST00000304043.10
ENST00000513012.2
HINT1
histidine triad nucleotide binding protein 1
chr16_-_74421756 0.52 ENST00000617101.4
CLEC18B
C-type lectin domain family 18 member B
chr2_+_44941695 0.51 ENST00000260653.5
SIX3
SIX homeobox 3
chr6_+_54099565 0.50 ENST00000511678.5
MLIP
muscular LMNA interacting protein
chr3_-_127288044 0.50 ENST00000465482.3
PRR20G
proline rich 20G
chr9_+_130664594 0.50 ENST00000253008.3
ENST00000676323.1
PRDM12
PR/SET domain 12
chr17_-_29005913 0.49 ENST00000442608.7
ENST00000317338.17
ENST00000335960.10
SEZ6
seizure related 6 homolog
chr12_+_25052694 0.48 ENST00000554942.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr14_+_64704102 0.48 ENST00000555982.5
PLEKHG3
pleckstrin homology and RhoGEF domain containing G3
chr8_+_106726012 0.47 ENST00000449762.6
ENST00000297447.10
OXR1
oxidation resistance 1
chr17_-_48968587 0.47 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr1_+_40709475 0.47 ENST00000372651.5
NFYC
nuclear transcription factor Y subunit gamma
chr5_-_131165272 0.47 ENST00000675491.1
ENST00000506908.2
HINT1
histidine triad nucleotide binding protein 1
chr7_-_78771058 0.47 ENST00000628781.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_75804221 0.47 ENST00000489941.6
ENST00000525373.5
LMO7
LIM domain 7
chr11_-_11353241 0.46 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr18_-_76495191 0.46 ENST00000443185.7
ZNF516
zinc finger protein 516
chr2_+_17816458 0.45 ENST00000281047.4
MSGN1
mesogenin 1
chr7_+_18495697 0.45 ENST00000413380.5
ENST00000430454.5
HDAC9
histone deacetylase 9
chr12_-_101210232 0.44 ENST00000536262.3
SLC5A8
solute carrier family 5 member 8
chr11_-_3837858 0.44 ENST00000396979.1
RHOG
ras homolog family member G
chrX_+_106693751 0.43 ENST00000418562.5
RNF128
ring finger protein 128
chr3_+_9792495 0.41 ENST00000498623.6
ARPC4
actin related protein 2/3 complex subunit 4
chr7_-_78771108 0.41 ENST00000626691.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_130344837 0.41 ENST00000485477.5
ENST00000431780.6
CPA5
carboxypeptidase A5
chr6_+_54099538 0.39 ENST00000447836.6
MLIP
muscular LMNA interacting protein
chr7_+_130344810 0.39 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
CPA5
carboxypeptidase A5
chr12_+_25052732 0.39 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr4_-_121227461 0.38 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr12_+_25052634 0.37 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr9_-_146140 0.37 ENST00000475990.5
CBWD1
COBW domain containing 1
chr4_+_168497113 0.37 ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr10_+_84194527 0.37 ENST00000623527.4
CDHR1
cadherin related family member 1
chr2_-_202911621 0.36 ENST00000261015.5
WDR12
WD repeat domain 12
chr14_+_22482287 0.36 ENST00000390484.1
TRAJ54
T cell receptor alpha joining 54
chr9_+_133636355 0.36 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr18_+_78980181 0.35 ENST00000616649.4
ENST00000575389.6
SALL3
spalt like transcription factor 3
chr11_+_46701010 0.34 ENST00000311764.3
ZNF408
zinc finger protein 408
chr10_+_92834594 0.34 ENST00000371552.8
EXOC6
exocyst complex component 6
chr7_+_90709231 0.34 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr3_-_157503574 0.33 ENST00000494677.5
ENST00000468233.5
VEPH1
ventricular zone expressed PH domain containing 1
chr1_+_244352627 0.33 ENST00000366537.5
ENST00000308105.5
C1orf100
chromosome 1 open reading frame 100
chr4_+_129096113 0.32 ENST00000508673.5
C4orf33
chromosome 4 open reading frame 33
chr7_+_151048526 0.32 ENST00000349064.10
ASIC3
acid sensing ion channel subunit 3
chr6_+_47781982 0.32 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
OPN5
opsin 5
chr14_+_64986846 0.31 ENST00000246166.3
FNTB
farnesyltransferase, CAAX box, beta
chr6_-_138499487 0.31 ENST00000343505.9
NHSL1
NHS like 1
chr22_-_30574572 0.31 ENST00000402369.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr8_+_49911801 0.30 ENST00000643809.1
SNTG1
syntrophin gamma 1
chr14_+_23240346 0.30 ENST00000430154.6
RNF212B
ring finger protein 212B
chr4_+_85827891 0.30 ENST00000514229.5
ARHGAP24
Rho GTPase activating protein 24
chr9_+_133636378 0.30 ENST00000263611.3
DBH
dopamine beta-hydroxylase
chr5_-_80654956 0.30 ENST00000439211.7
DHFR
dihydrofolate reductase
chr7_-_151210488 0.29 ENST00000644661.2
H2BE1
H2B.E variant histone 1
chr1_+_248508073 0.29 ENST00000641804.1
OR2G6
olfactory receptor family 2 subfamily G member 6
chr7_+_90709530 0.29 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr7_+_90709816 0.29 ENST00000436577.3
CDK14
cyclin dependent kinase 14
chr12_-_86256267 0.28 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr4_-_83114715 0.28 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
PLAC8
placenta associated 8
chr8_+_106726115 0.28 ENST00000521592.5
OXR1
oxidation resistance 1
chr2_+_168901290 0.28 ENST00000429379.2
ENST00000375363.8
ENST00000421979.1
G6PC2
glucose-6-phosphatase catalytic subunit 2
chr12_-_52434363 0.28 ENST00000252245.6
KRT75
keratin 75
chr12_-_52618559 0.27 ENST00000305748.7
KRT73
keratin 73
chr3_-_57199938 0.26 ENST00000473921.2
ENST00000295934.8
HESX1
HESX homeobox 1
chr15_-_32888239 0.26 ENST00000559610.1
FMN1
formin 1
chr3_-_71360753 0.26 ENST00000648783.1
FOXP1
forkhead box P1
chr18_-_26657401 0.25 ENST00000580191.5
KCTD1
potassium channel tetramerization domain containing 1
chr1_+_174447944 0.24 ENST00000367685.5
GPR52
G protein-coupled receptor 52
chr8_-_102412686 0.24 ENST00000220959.8
ENST00000520539.6
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr14_+_74239447 0.24 ENST00000261980.3
VSX2
visual system homeobox 2
chr11_+_59436469 0.23 ENST00000641045.1
OR5A1
olfactory receptor family 5 subfamily A member 1
chr4_+_122239965 0.22 ENST00000446180.5
KIAA1109
KIAA1109
chr13_-_103066411 0.22 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr12_+_64405046 0.22 ENST00000540203.5
XPOT
exportin for tRNA
chrX_+_123963164 0.21 ENST00000394478.1
STAG2
stromal antigen 2
chr6_+_101398788 0.21 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr3_+_112041920 0.21 ENST00000617607.4
TMPRSS7
transmembrane serine protease 7
chr11_-_27722021 0.20 ENST00000314915.6
BDNF
brain derived neurotrophic factor
chr1_+_42825548 0.20 ENST00000372514.7
ERMAP
erythroblast membrane associated protein (Scianna blood group)
chr16_-_57946602 0.19 ENST00000564654.1
CNGB1
cyclic nucleotide gated channel subunit beta 1
chr17_-_50707855 0.19 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40
chr11_+_124566660 0.19 ENST00000641670.1
OR8A1
olfactory receptor family 8 subfamily A member 1
chr12_-_89352487 0.19 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr6_-_49713521 0.19 ENST00000339139.5
CRISP2
cysteine rich secretory protein 2
chr7_+_18496269 0.19 ENST00000432645.6
HDAC9
histone deacetylase 9
chr12_+_56080126 0.18 ENST00000411731.6
ERBB3
erb-b2 receptor tyrosine kinase 3
chr4_+_112860912 0.17 ENST00000671951.1
ANK2
ankyrin 2
chr12_+_52301833 0.16 ENST00000293525.5
KRT86
keratin 86
chr4_+_112860981 0.16 ENST00000671704.1
ANK2
ankyrin 2
chr1_+_40709316 0.16 ENST00000372652.5
NFYC
nuclear transcription factor Y subunit gamma
chr11_-_124320197 0.15 ENST00000624618.2
OR8D2
olfactory receptor family 8 subfamily D member 2
chr10_-_54801262 0.15 ENST00000373965.6
ENST00000616114.4
ENST00000621708.4
ENST00000495484.5
ENST00000395440.5
ENST00000395442.5
ENST00000617271.4
ENST00000395446.5
ENST00000409834.5
ENST00000361849.7
ENST00000373957.7
ENST00000395430.5
ENST00000395433.5
ENST00000437009.5
PCDH15
protocadherin related 15
chr22_-_30574511 0.15 ENST00000431313.5
GAL3ST1
galactose-3-O-sulfotransferase 1
chr6_-_39725387 0.15 ENST00000287152.12
KIF6
kinesin family member 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.8 3.9 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.8 3.9 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.7 2.2 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.6 2.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 4.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.6 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.3 0.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 0.5 GO:0009946 proximal/distal axis specification(GO:0009946)
0.2 2.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 0.7 GO:0042309 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
0.2 3.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.6 GO:0045175 basal protein localization(GO:0045175)
0.2 1.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 1.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.5 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.8 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.7 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.8 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 2.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 1.4 GO:0019532 oxalate transport(GO:0019532)
0.1 1.0 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.5 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.5 GO:0007614 short-term memory(GO:0007614)
0.1 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.9 GO:0097186 amelogenesis(GO:0097186)
0.1 0.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.5 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.7 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.9 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 1.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 1.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 3.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 2.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.0 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 1.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.1 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.5 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.4 4.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 3.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 3.9 GO:0010369 chromocenter(GO:0010369)
0.1 1.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.4 GO:0036019 endolysosome(GO:0036019)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.1 GO:0000800 lateral element(GO:0000800)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 2.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 3.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.1 2.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 1.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 4.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.5 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0031433 telethonin binding(GO:0031433)
0.0 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 2.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.0 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 3.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 4.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 2.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 5.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 2.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing