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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for EMX2

Z-value: 0.84

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.12 EMX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg38_v1_chr10_+_117542416_1175424450.154.2e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_53962925 4.17 ENST00000270458.4
CACNG8
calcium voltage-gated channel auxiliary subunit gamma 8
chr2_+_17541157 2.37 ENST00000406397.1
VSNL1
visinin like 1
chr10_-_20897288 2.14 ENST00000377122.9
NEBL
nebulette
chr6_+_13272709 2.12 ENST00000379335.8
PHACTR1
phosphatase and actin regulator 1
chr17_-_40937641 2.09 ENST00000209718.8
KRT23
keratin 23
chr1_+_149782671 2.01 ENST00000444948.5
ENST00000369168.5
FCGR1A
Fc fragment of IgG receptor Ia
chr4_-_88284553 1.91 ENST00000608933.6
ENST00000295908.11
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr4_-_88284616 1.89 ENST00000508256.5
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr5_-_74866958 1.88 ENST00000389156.9
FAM169A
family with sequence similarity 169 member A
chr18_-_26865689 1.87 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
AQP4
aquaporin 4
chr1_+_84181630 1.83 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr9_+_12695702 1.79 ENST00000381136.2
TYRP1
tyrosinase related protein 1
chr5_+_36608146 1.77 ENST00000381918.4
ENST00000513646.1
SLC1A3
solute carrier family 1 member 3
chr17_-_40937445 1.76 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr4_-_88284590 1.74 ENST00000510548.6
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chrX_+_154304923 1.70 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
TKTL1
transketolase like 1
chr18_-_26865732 1.53 ENST00000672188.1
AQP4
aquaporin 4
chr16_+_85027735 1.52 ENST00000258180.7
ENST00000538274.5
KIAA0513
KIAA0513
chr4_-_88284747 1.46 ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr16_-_46748337 1.45 ENST00000394809.9
MYLK3
myosin light chain kinase 3
chr3_-_132037800 1.45 ENST00000617767.4
CPNE4
copine 4
chr1_+_192809031 1.45 ENST00000235382.7
RGS2
regulator of G protein signaling 2
chr12_+_59689337 1.40 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr1_+_84144260 1.32 ENST00000370685.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr6_+_72216442 1.27 ENST00000425662.6
ENST00000453976.6
RIMS1
regulating synaptic membrane exocytosis 1
chrX_+_18425597 1.27 ENST00000623535.2
ENST00000674046.1
CDKL5
cyclin dependent kinase like 5
chr5_-_138139382 1.26 ENST00000265191.4
NME5
NME/NM23 family member 5
chr20_+_9514562 1.26 ENST00000246070.3
LAMP5
lysosomal associated membrane protein family member 5
chr2_-_44323302 1.23 ENST00000420756.1
ENST00000444696.5
PREPL
prolyl endopeptidase like
chr3_-_196515315 1.23 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chrX_-_73214793 1.21 ENST00000373517.4
NAP1L2
nucleosome assembly protein 1 like 2
chr17_-_59081162 1.18 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr3_-_151329539 1.16 ENST00000325602.6
P2RY13
purinergic receptor P2Y13
chr5_-_11588842 1.15 ENST00000503622.5
CTNND2
catenin delta 2
chrX_-_23907887 1.08 ENST00000379226.9
APOO
apolipoprotein O
chr2_-_2324323 1.06 ENST00000648339.1
ENST00000647694.1
MYT1L
myelin transcription factor 1 like
chr12_-_86256299 1.06 ENST00000552808.6
ENST00000547225.5
MGAT4C
MGAT4 family member C
chr2_-_206159410 1.03 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr5_-_111976925 1.02 ENST00000395634.7
NREP
neuronal regeneration related protein
chr12_-_10130143 1.02 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
CLEC7A
C-type lectin domain containing 7A
chr11_+_119149029 0.99 ENST00000619701.5
ABCG4
ATP binding cassette subfamily G member 4
chr16_+_56191476 0.98 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr10_+_27532521 0.98 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chrX_+_18425579 0.97 ENST00000379996.7
CDKL5
cyclin dependent kinase like 5
chr1_+_152878312 0.96 ENST00000368765.4
SMCP
sperm mitochondria associated cysteine rich protein
chr15_+_77420957 0.96 ENST00000559099.5
HMG20A
high mobility group 20A
chr2_-_208186999 0.94 ENST00000453017.5
ENST00000423952.2
C2orf80
chromosome 2 open reading frame 80
chr5_-_74866914 0.93 ENST00000513277.5
FAM169A
family with sequence similarity 169 member A
chr8_-_73582830 0.93 ENST00000523533.5
STAU2
staufen double-stranded RNA binding protein 2
chr14_+_24070837 0.92 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
CPNE6
copine 6
chr2_+_227871618 0.91 ENST00000309931.3
ENST00000440997.1
DAW1
dynein assembly factor with WD repeats 1
chr1_+_92168915 0.91 ENST00000637221.2
BTBD8
BTB domain containing 8
chr6_-_110179855 0.90 ENST00000368938.5
WASF1
WASP family member 1
chr6_-_110179995 0.89 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASF1
WASP family member 1
chr1_+_178513103 0.89 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
TEX35
testis expressed 35
chr12_+_10010627 0.88 ENST00000338896.11
ENST00000396502.5
CLEC12B
C-type lectin domain family 12 member B
chr9_+_108862255 0.88 ENST00000333999.5
ACTL7A
actin like 7A
chr1_-_66801276 0.88 ENST00000304526.3
INSL5
insulin like 5
chr11_-_129024157 0.87 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr1_+_117001744 0.86 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101
CD101 molecule
chr8_-_142777802 0.86 ENST00000621401.4
LYNX1
Ly6/neurotoxin 1
chr20_+_4686448 0.86 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
PRNP
prion protein
chr15_+_77420668 0.85 ENST00000381714.7
ENST00000558651.5
HMG20A
high mobility group 20A
chr3_-_20012250 0.85 ENST00000389050.5
PP2D1
protein phosphatase 2C like domain containing 1
chr3_+_111674654 0.84 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
PLCXD2
phosphatidylinositol specific phospholipase C X domain containing 2
chr20_+_9514340 0.83 ENST00000427562.6
LAMP5
lysosomal associated membrane protein family member 5
chr1_-_173205543 0.83 ENST00000367718.5
TNFSF4
TNF superfamily member 4
chr11_+_12094008 0.83 ENST00000532179.5
ENST00000526065.1
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr2_-_206159509 0.82 ENST00000423725.5
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr14_+_101809795 0.82 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
chr1_+_39158841 0.81 ENST00000672812.1
MACF1
microtubule actin crosslinking factor 1
chr1_+_36084079 0.80 ENST00000207457.8
TEKT2
tektin 2
chr1_+_177170916 0.80 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chrX_+_106168297 0.80 ENST00000337685.6
ENST00000357175.6
PWWP3B
PWWP domain containing 3B
chr20_+_15196834 0.79 ENST00000402914.5
MACROD2
mono-ADP ribosylhydrolase 2
chr5_-_140633656 0.78 ENST00000519715.1
CD14
CD14 molecule
chr13_+_108269629 0.78 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr18_+_57352541 0.78 ENST00000324000.4
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_230759918 0.78 ENST00000614925.1
CAB39
calcium binding protein 39
chr5_+_162068031 0.77 ENST00000356592.8
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr12_-_10130241 0.77 ENST00000353231.9
ENST00000525605.1
CLEC7A
C-type lectin domain containing 7A
chr4_-_159035226 0.77 ENST00000434826.3
C4orf45
chromosome 4 open reading frame 45
chr3_+_141262614 0.77 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr12_+_28452493 0.76 ENST00000542801.5
CCDC91
coiled-coil domain containing 91
chr3_-_109118098 0.76 ENST00000483760.1
MORC1
MORC family CW-type zinc finger 1
chr17_+_68525795 0.75 ENST00000592800.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr5_+_162067858 0.74 ENST00000361925.9
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_-_105035113 0.74 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
CASP1
caspase 1
chr1_-_212414815 0.72 ENST00000261455.9
ENST00000535273.2
PACC1
proton activated chloride channel 1
chr10_+_89332484 0.72 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
IFIT3
interferon induced protein with tetratricopeptide repeats 3
chr6_+_101181254 0.71 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr7_+_123601859 0.70 ENST00000437535.5
ASB15
ankyrin repeat and SOCS box containing 15
chr5_-_140633690 0.70 ENST00000512545.1
ENST00000401743.6
CD14
CD14 molecule
chr2_+_11556337 0.70 ENST00000234142.9
GREB1
growth regulating estrogen receptor binding 1
chr9_+_128566741 0.70 ENST00000630866.1
SPTAN1
spectrin alpha, non-erythrocytic 1
chr4_-_185649524 0.69 ENST00000451974.5
SORBS2
sorbin and SH3 domain containing 2
chr1_+_173635332 0.68 ENST00000417563.3
TEX50
testis expressed 50
chr16_-_21652598 0.68 ENST00000569602.1
ENST00000268389.6
IGSF6
immunoglobulin superfamily member 6
chr2_-_206159194 0.68 ENST00000455934.6
ENST00000449699.5
ENST00000454195.1
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr5_+_173890545 0.68 ENST00000519152.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr5_-_140633639 0.67 ENST00000498971.6
CD14
CD14 molecule
chr6_+_101398788 0.66 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr8_-_33599935 0.66 ENST00000523956.1
ENST00000256261.9
DUSP26
dual specificity phosphatase 26
chr17_-_76141240 0.65 ENST00000322957.7
FOXJ1
forkhead box J1
chr11_-_84166998 0.65 ENST00000398299.1
DLG2
discs large MAGUK scaffold protein 2
chr5_+_58491427 0.64 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GAPT
GRB2 binding adaptor protein, transmembrane
chr19_-_51417700 0.64 ENST00000529627.1
ENST00000439889.6
SIGLEC10
sialic acid binding Ig like lectin 10
chrX_-_6535118 0.63 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
VCX3A
variable charge X-linked 3A
chr1_+_103561757 0.63 ENST00000435302.5
AMY2B
amylase alpha 2B
chr7_-_105269007 0.63 ENST00000357311.7
SRPK2
SRSF protein kinase 2
chr5_-_142686047 0.63 ENST00000360966.9
ENST00000411960.1
FGF1
fibroblast growth factor 1
chr5_+_162067990 0.63 ENST00000641017.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr7_+_48924559 0.63 ENST00000650262.1
CDC14C
cell division cycle 14C
chr8_+_66775178 0.63 ENST00000396596.2
ENST00000521960.5
ENST00000522398.5
ENST00000522629.5
ENST00000520976.5
SGK3
serum/glucocorticoid regulated kinase family member 3
chr11_+_5689691 0.62 ENST00000425490.5
TRIM22
tripartite motif containing 22
chr17_+_68035636 0.62 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
KPNA2
karyopherin subunit alpha 2
chr5_+_134967901 0.62 ENST00000282611.8
CATSPER3
cation channel sperm associated 3
chr19_-_51417791 0.60 ENST00000353836.9
SIGLEC10
sialic acid binding Ig like lectin 10
chrX_-_77969638 0.60 ENST00000458128.3
PGAM4
phosphoglycerate mutase family member 4
chr5_-_11588796 0.60 ENST00000513598.5
CTNND2
catenin delta 2
chrY_+_14056226 0.59 ENST00000250823.5
VCY1B
variable charge Y-linked 1B
chr5_+_169695135 0.59 ENST00000523684.5
ENST00000519734.5
DOCK2
dedicator of cytokinesis 2
chr4_+_121801311 0.58 ENST00000379663.7
ENST00000243498.10
ENST00000509800.5
EXOSC9
exosome component 9
chr1_+_198638457 0.58 ENST00000367379.6
PTPRC
protein tyrosine phosphatase receptor type C
chr7_+_123601836 0.57 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr8_-_132675533 0.57 ENST00000620350.5
ENST00000518642.5
ENST00000250173.5
LRRC6
leucine rich repeat containing 6
chr9_-_5833014 0.57 ENST00000339450.10
ERMP1
endoplasmic reticulum metallopeptidase 1
chr15_+_77420880 0.57 ENST00000336216.9
ENST00000558176.1
HMG20A
high mobility group 20A
chr20_-_31390580 0.57 ENST00000339144.3
ENST00000376321.4
DEFB119
defensin beta 119
chr15_-_42208153 0.57 ENST00000348544.4
ENST00000318006.10
VPS39
VPS39 subunit of HOPS complex
chr3_-_49429252 0.56 ENST00000615713.4
NICN1
nicolin 1
chr5_+_142907573 0.55 ENST00000469131.6
ARHGAP26
Rho GTPase activating protein 26
chr18_+_34710249 0.55 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
DTNA
dystrobrevin alpha
chr14_-_80231052 0.55 ENST00000557010.5
DIO2
iodothyronine deiodinase 2
chr5_-_177780633 0.54 ENST00000513554.5
ENST00000440605.7
FAM153A
family with sequence similarity 153 member A
chr3_-_108058361 0.54 ENST00000398258.7
CD47
CD47 molecule
chr1_+_174875505 0.52 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr1_-_120051714 0.52 ENST00000579475.7
NOTCH2
notch receptor 2
chr12_-_10130082 0.52 ENST00000533022.5
CLEC7A
C-type lectin domain containing 7A
chr11_+_27055215 0.52 ENST00000525090.1
BBOX1
gamma-butyrobetaine hydroxylase 1
chr3_+_72888031 0.51 ENST00000389617.9
GXYLT2
glucoside xylosyltransferase 2
chr5_+_160009113 0.51 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
TTC1
tetratricopeptide repeat domain 1
chr1_+_86547070 0.50 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr14_+_103385374 0.50 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
MARK3
microtubule affinity regulating kinase 3
chr3_-_49429304 0.50 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
ENSG00000283189.2
NICN1
novel protein
nicolin 1
chr8_+_27380629 0.49 ENST00000412793.5
PTK2B
protein tyrosine kinase 2 beta
chr17_-_62806632 0.49 ENST00000583803.1
ENST00000456609.6
MARCHF10
membrane associated ring-CH-type finger 10
chr1_+_78649818 0.48 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chr11_-_26572254 0.48 ENST00000529533.6
MUC15
mucin 15, cell surface associated
chr8_-_53842899 0.48 ENST00000524234.1
ENST00000521275.5
ENST00000396774.6
ATP6V1H
ATPase H+ transporting V1 subunit H
chr2_-_169694332 0.48 ENST00000421028.1
CCDC173
coiled-coil domain containing 173
chr15_+_21579912 0.48 ENST00000628444.1
LINC02203
long intergenic non-protein coding RNA 2203
chr3_+_131026844 0.48 ENST00000510769.5
ENST00000383366.9
ENST00000510688.5
ENST00000511262.5
NEK11
NIMA related kinase 11
chrX_+_136648214 0.47 ENST00000370628.2
CD40LG
CD40 ligand
chr10_-_114144599 0.46 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chr15_+_22015233 0.46 ENST00000639059.1
ENST00000640156.1
ENSG00000285472.1
ENSG00000284500.3
novel protein
novel transcript
chr1_-_17045219 0.46 ENST00000491274.5
SDHB
succinate dehydrogenase complex iron sulfur subunit B
chr4_-_99435396 0.46 ENST00000209665.8
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_-_112433519 0.45 ENST00000496537.1
ENST00000330575.9
ENST00000302558.8
RGPD8
RANBP2 like and GRIP domain containing 8
chr7_+_142791635 0.45 ENST00000633705.1
TRBC1
T cell receptor beta constant 1
chr7_+_123601815 0.45 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr1_-_155969724 0.45 ENST00000609707.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr12_+_29149238 0.45 ENST00000536681.8
FAR2
fatty acyl-CoA reductase 2
chr16_+_18983927 0.45 ENST00000569532.5
ENST00000304381.10
TMC7
transmembrane channel like 7
chr2_-_73779968 0.45 ENST00000452812.1
ENST00000443070.5
ENST00000272444.7
DUSP11
dual specificity phosphatase 11
chr4_+_94974984 0.45 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr1_-_170074568 0.44 ENST00000367767.5
ENST00000361580.7
ENST00000538366.5
KIFAP3
kinesin associated protein 3
chr3_-_196270540 0.44 ENST00000419333.5
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr16_+_31873772 0.44 ENST00000394846.7
ENST00000300870.15
ZNF267
zinc finger protein 267
chr2_-_98663464 0.43 ENST00000414521.6
MGAT4A
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr2_+_109794296 0.43 ENST00000430736.5
ENST00000016946.8
ENST00000441344.1
RGPD5
RANBP2 like and GRIP domain containing 5
chrX_+_136648138 0.43 ENST00000370629.7
CD40LG
CD40 ligand
chr16_-_11281322 0.43 ENST00000312511.4
PRM1
protamine 1
chr4_-_175891691 0.43 ENST00000507540.1
GPM6A
glycoprotein M6A
chr12_+_9827517 0.43 ENST00000537723.5
KLRF1
killer cell lectin like receptor F1
chr11_-_46119787 0.42 ENST00000529782.5
ENST00000532010.5
ENST00000525438.5
ENST00000533757.5
ENST00000527782.5
PHF21A
PHD finger protein 21A
chr8_+_103880412 0.41 ENST00000436393.6
RIMS2
regulating synaptic membrane exocytosis 2
chrX_+_77910656 0.41 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr12_-_86256267 0.41 ENST00000620241.4
MGAT4C
MGAT4 family member C
chr10_-_30629741 0.41 ENST00000647634.2
ENST00000375318.4
LYZL2
lysozyme like 2
chr4_+_168654724 0.40 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr17_-_73227700 0.40 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104 member A
chr10_-_24622817 0.39 ENST00000636789.1
ARHGAP21
Rho GTPase activating protein 21
chr3_-_131026726 0.39 ENST00000514044.5
ENST00000264992.8
ASTE1
asteroid homolog 1
chr4_+_94207596 0.39 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_+_74537787 0.39 ENST00000519948.4
ATXN7L3B
ataxin 7 like 3B
chr12_-_49130113 0.39 ENST00000549870.5
TUBA1B
tubulin alpha 1b
chrX_+_23908006 0.39 ENST00000379211.8
ENST00000648352.1
CXorf58
chromosome X open reading frame 58
chr6_+_32439866 0.39 ENST00000374982.5
ENST00000395388.7
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr4_-_99435336 0.39 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_60073750 0.39 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr12_-_118359639 0.38 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr12_+_125065427 0.38 ENST00000316519.11
AACS
acetoacetyl-CoA synthetase
chr2_+_11542662 0.38 ENST00000389825.7
ENST00000381483.6
GREB1
growth regulating estrogen receptor binding 1
chr3_+_122055355 0.38 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr22_-_39893755 0.37 ENST00000325157.7
ENTHD1
ENTH domain containing 1
chr2_-_110577101 0.37 ENST00000330331.9
ENST00000446930.1
ENST00000329516.8
RGPD6
RANBP2 like and GRIP domain containing 6
chr6_+_110180418 0.37 ENST00000368930.5
ENST00000307731.2
CDC40
cell division cycle 40
chr13_+_48256214 0.37 ENST00000650237.1
ITM2B
integral membrane protein 2B
chr12_-_68159732 0.36 ENST00000229135.4
IFNG
interferon gamma

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.4 1.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 3.1 GO:0097338 response to clozapine(GO:0097338)
0.3 0.9 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.3 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 1.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.3 1.7 GO:0006772 thiamine metabolic process(GO:0006772)
0.3 0.8 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 0.8 GO:0019417 sulfur oxidation(GO:0019417)
0.3 2.2 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.9 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.8 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 0.8 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.6 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 6.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 0.7 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 1.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 1.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 1.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 1.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.4 GO:0060003 copper ion export(GO:0060003)
0.1 1.4 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1 0.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.8 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.4 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.1 0.4 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.6 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 4.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.6 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1 2.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.2 GO:0016121 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.6 GO:0072139 negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 1.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.8 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 3.0 GO:0006833 water transport(GO:0006833)
0.1 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.3 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 1.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 2.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.6 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.8 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 2.2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 2.2 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 1.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 3.5 GO:0070268 cornification(GO:0070268)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 3.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.3 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0046070 dGTP metabolic process(GO:0046070)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.7 GO:0051693 actin filament capping(GO:0051693)
0.0 2.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.2 2.1 GO:0032584 growth cone membrane(GO:0032584)
0.2 2.2 GO:0044294 dendritic growth cone(GO:0044294)
0.2 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939)
0.1 3.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0072558 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.5 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 4.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0036128 CatSper complex(GO:0036128)
0.0 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 2.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 3.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.4 1.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 1.7 GO:0004802 transketolase activity(GO:0004802)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.3 2.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 2.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.9 GO:1903135 cupric ion binding(GO:1903135)
0.2 3.4 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 1.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0043682 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) superoxide dismutase copper chaperone activity(GO:0016532) copper-transporting ATPase activity(GO:0043682)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 3.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 2.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 2.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.3 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 8.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.9 GO:0030547 receptor inhibitor activity(GO:0030547)
0.1 4.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 1.0 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 1.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 2.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 4.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 3.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 3.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules