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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for GGCAGUG

Z-value: 1.30

Motif logo

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miRNA associated with seed GGCAGUG

NamemiRBASE accession
hsa-miR-34a-5p
MIMAT0000255
hsa-miR-34c-5p
MIMAT0000686
hsa-miR-449a
MIMAT0001541
hsa-miR-449b-5p
MIMAT0003327

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_175796310 9.23 ENST00000359546.8
CPLX2
complexin 2
chr20_+_10218808 8.64 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr10_+_103277129 8.54 ENST00000369849.9
INA
internexin neuronal intermediate filament protein alpha
chr1_+_205043204 8.32 ENST00000331830.7
CNTN2
contactin 2
chr12_+_78864768 8.20 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr13_-_25172278 6.11 ENST00000515384.2
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr16_+_56191476 5.09 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr22_+_41976933 4.85 ENST00000396425.7
SEPTIN3
septin 3
chr9_+_34958254 4.68 ENST00000242315.3
PHF24
PHD finger protein 24
chr11_-_118176576 4.54 ENST00000278947.6
SCN2B
sodium voltage-gated channel beta subunit 2
chr7_+_94656325 4.42 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
PEG10
paternally expressed 10
chrX_-_152451273 4.30 ENST00000370314.9
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
chr5_+_111224374 4.23 ENST00000282356.9
CAMK4
calcium/calmodulin dependent protein kinase IV
chr5_-_11904417 4.14 ENST00000304623.13
CTNND2
catenin delta 2
chr9_-_98708856 4.12 ENST00000259455.4
GABBR2
gamma-aminobutyric acid type B receptor subunit 2
chr1_+_162069674 4.11 ENST00000361897.10
NOS1AP
nitric oxide synthase 1 adaptor protein
chr6_+_96015964 4.01 ENST00000302103.6
FUT9
fucosyltransferase 9
chr11_+_107591077 3.95 ENST00000531234.5
ENST00000265840.12
ELMOD1
ELMO domain containing 1
chr16_+_87602478 3.95 ENST00000284262.3
JPH3
junctophilin 3
chr3_-_180036918 3.89 ENST00000465751.5
ENST00000467460.6
ENST00000472994.5
PEX5L
peroxisomal biogenesis factor 5 like
chr12_-_57742120 3.88 ENST00000257897.7
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_+_110150480 3.85 ENST00000331565.5
SLC6A17
solute carrier family 6 member 17
chr20_+_38805686 3.73 ENST00000299824.6
ENST00000373331.2
PPP1R16B
protein phosphatase 1 regulatory subunit 16B
chr7_+_146116772 3.67 ENST00000361727.8
CNTNAP2
contactin associated protein 2
chr18_-_72867945 3.60 ENST00000327305.11
NETO1
neuropilin and tolloid like 1
chr10_-_60389833 3.53 ENST00000280772.7
ANK3
ankyrin 3
chr17_-_43900596 3.48 ENST00000377184.7
MPP2
membrane palmitoylated protein 2
chr1_-_40665654 3.46 ENST00000372684.8
RIMS3
regulating synaptic membrane exocytosis 3
chr17_-_39225936 3.45 ENST00000333461.6
STAC2
SH3 and cysteine rich domain 2
chr8_-_132481057 3.44 ENST00000388996.10
KCNQ3
potassium voltage-gated channel subfamily Q member 3
chr18_+_69400852 3.41 ENST00000382713.10
DOK6
docking protein 6
chr6_-_110179702 3.31 ENST00000392587.6
WASF1
WASP family member 1
chr22_+_26429246 3.26 ENST00000215906.6
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr18_+_57352541 3.26 ENST00000324000.4
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_+_25174969 3.26 ENST00000376351.4
GPR158
G protein-coupled receptor 158
chr12_-_13981544 3.16 ENST00000609686.4
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
chr9_+_124011738 3.16 ENST00000373615.9
LHX2
LIM homeobox 2
chr15_+_59438149 3.10 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
FAM81A
family with sequence similarity 81 member A
chr13_-_26760741 3.09 ENST00000405846.5
GPR12
G protein-coupled receptor 12
chr10_+_93758063 3.04 ENST00000627699.1
ENST00000371413.4
LGI1
leucine rich glioma inactivated 1
chr4_+_47031551 3.03 ENST00000295454.8
GABRB1
gamma-aminobutyric acid type A receptor subunit beta1
chr15_+_51751587 2.92 ENST00000539962.6
ENST00000249700.9
TMOD2
tropomodulin 2
chr22_-_36703723 2.85 ENST00000300105.7
CACNG2
calcium voltage-gated channel auxiliary subunit gamma 2
chr2_-_27263034 2.85 ENST00000233535.9
SLC30A3
solute carrier family 30 member 3
chr2_+_104854104 2.84 ENST00000361360.4
POU3F3
POU class 3 homeobox 3
chr4_+_98261368 2.80 ENST00000509011.5
ENST00000408927.8
ENST00000380158.8
ENST00000264572.11
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr19_-_55443263 2.75 ENST00000416792.2
ENST00000376325.10
SHISA7
shisa family member 7
chr3_+_113532508 2.73 ENST00000264852.9
SIDT1
SID1 transmembrane family member 1
chr8_-_59119121 2.73 ENST00000361421.2
TOX
thymocyte selection associated high mobility group box
chr2_+_15940537 2.70 ENST00000281043.4
ENST00000638417.1
MYCN
MYCN proto-oncogene, bHLH transcription factor
chr7_+_107470050 2.60 ENST00000304402.6
GPR22
G protein-coupled receptor 22
chr3_+_39809602 2.57 ENST00000302541.11
ENST00000396217.7
MYRIP
myosin VIIA and Rab interacting protein
chr17_-_33293247 2.56 ENST00000225823.7
ASIC2
acid sensing ion channel subunit 2
chr17_+_42682470 2.54 ENST00000264638.9
CNTNAP1
contactin associated protein 1
chr17_-_1179940 2.50 ENST00000302538.10
ABR
ABR activator of RhoGEF and GTPase
chr1_-_151716052 2.49 ENST00000290585.8
CELF3
CUGBP Elav-like family member 3
chr9_+_100442271 2.48 ENST00000502978.1
MSANTD3-TMEFF1
MSANTD3-TMEFF1 readthrough
chr7_+_87934143 2.48 ENST00000398204.8
ADAM22
ADAM metallopeptidase domain 22
chr11_-_134411854 2.48 ENST00000392580.5
B3GAT1
beta-1,3-glucuronyltransferase 1
chr11_+_7251886 2.47 ENST00000318881.11
SYT9
synaptotagmin 9
chr17_+_45894515 2.44 ENST00000680674.1
ENST00000535772.6
ENST00000351559.10
ENST00000262410.10
ENST00000344290.10
MAPT
microtubule associated protein tau
chr19_-_43639788 2.43 ENST00000222374.3
CADM4
cell adhesion molecule 4
chr15_+_43510945 2.41 ENST00000382031.5
MAP1A
microtubule associated protein 1A
chr11_-_9003994 2.39 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
NRIP3
nuclear receptor interacting protein 3
chr3_-_172711005 2.28 ENST00000424772.2
ENST00000475381.7
NCEH1
neutral cholesterol ester hydrolase 1
chr9_-_10612966 2.28 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr7_+_20330893 2.25 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr17_-_8163522 2.24 ENST00000404970.3
VAMP2
vesicle associated membrane protein 2
chr9_-_101487091 2.23 ENST00000374847.5
PGAP4
post-GPI attachment to proteins GalNAc transferase 4
chr11_-_64643315 2.22 ENST00000301894.6
NRXN2
neurexin 2
chr9_-_119369416 2.19 ENST00000373964.2
ENST00000265922.8
BRINP1
BMP/retinoic acid inducible neural specific 1
chr8_+_11284789 2.10 ENST00000221086.8
MTMR9
myotubularin related protein 9
chr14_-_54489003 2.09 ENST00000554908.5
ENST00000616146.4
GMFB
glia maturation factor beta
chr11_+_57181945 2.07 ENST00000497933.3
LRRC55
leucine rich repeat containing 55
chr17_+_44758958 2.06 ENST00000200557.11
ADAM11
ADAM metallopeptidase domain 11
chr15_-_44194407 2.06 ENST00000484674.5
FRMD5
FERM domain containing 5
chr1_+_31296989 2.05 ENST00000373714.5
ENST00000344147.10
ENST00000627541.1
ZCCHC17
zinc finger CCHC-type containing 17
chr1_+_160115715 2.05 ENST00000361216.8
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr21_+_43719095 2.02 ENST00000468090.5
ENST00000291565.9
PDXK
pyridoxal kinase
chr10_+_132186937 2.01 ENST00000338492.9
DPYSL4
dihydropyrimidinase like 4
chr3_+_184230373 2.01 ENST00000426955.6
VWA5B2
von Willebrand factor A domain containing 5B2
chr17_-_39607876 1.97 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr4_+_113049616 1.96 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ANK2
ankyrin 2
chr8_-_11466740 1.82 ENST00000284486.9
FAM167A
family with sequence similarity 167 member A
chr5_+_64505981 1.81 ENST00000334025.3
RGS7BP
regulator of G protein signaling 7 binding protein
chr8_-_80171496 1.79 ENST00000379096.9
ENST00000518937.6
TPD52
tumor protein D52
chr5_+_144205250 1.76 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr6_-_6006878 1.73 ENST00000244766.7
NRN1
neuritin 1
chr11_-_119729158 1.70 ENST00000264025.8
NECTIN1
nectin cell adhesion molecule 1
chr2_-_40452046 1.70 ENST00000406785.6
SLC8A1
solute carrier family 8 member A1
chrX_+_114584037 1.67 ENST00000371951.5
ENST00000371950.3
ENST00000276198.6
HTR2C
5-hydroxytryptamine receptor 2C
chrX_+_65488735 1.62 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr3_-_123449083 1.62 ENST00000462833.6
ADCY5
adenylate cyclase 5
chr1_-_21669301 1.61 ENST00000542643.6
ENST00000317967.11
ENST00000374765.9
ENST00000290101.8
RAP1GAP
RAP1 GTPase activating protein
chr16_-_4538819 1.59 ENST00000564828.5
CDIP1
cell death inducing p53 target 1
chr2_-_70768175 1.59 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
ADD2
adducin 2
chr3_-_185152974 1.56 ENST00000335012.3
C3orf70
chromosome 3 open reading frame 70
chr6_+_46652968 1.56 ENST00000371347.10
SLC25A27
solute carrier family 25 member 27
chr19_+_18683656 1.56 ENST00000338797.10
ENST00000321949.13
CRTC1
CREB regulated transcription coactivator 1
chr10_-_133424572 1.55 ENST00000414069.2
SPRN
shadow of prion protein
chr9_+_100473140 1.48 ENST00000374879.5
TMEFF1
transmembrane protein with EGF like and two follistatin like domains 1
chr9_+_112750722 1.46 ENST00000374232.8
SNX30
sorting nexin family member 30
chr15_-_31870651 1.44 ENST00000307050.6
ENST00000560598.2
OTUD7A
OTU deubiquitinase 7A
chr1_+_66332004 1.42 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
PDE4B
phosphodiesterase 4B
chr16_+_28292485 1.42 ENST00000341901.5
SBK1
SH3 domain binding kinase 1
chr12_-_40106026 1.40 ENST00000280871.9
ENST00000380858.1
SLC2A13
solute carrier family 2 member 13
chrX_+_23334841 1.40 ENST00000379361.5
PTCHD1
patched domain containing 1
chr8_+_28317265 1.39 ENST00000301908.8
PNOC
prepronociceptin
chr1_+_160205374 1.38 ENST00000368077.5
ENST00000360472.9
PEA15
proliferation and apoptosis adaptor protein 15
chr12_+_107318395 1.37 ENST00000420571.6
ENST00000280758.10
BTBD11
BTB domain containing 11
chr11_-_22829793 1.36 ENST00000354193.5
SVIP
small VCP interacting protein
chr2_-_73269483 1.31 ENST00000295133.9
FBXO41
F-box protein 41
chr12_+_64780465 1.30 ENST00000542120.6
TBC1D30
TBC1 domain family member 30
chr2_+_238426920 1.29 ENST00000264607.9
ASB1
ankyrin repeat and SOCS box containing 1
chr1_+_84078043 1.29 ENST00000370689.6
ENST00000370688.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_+_76764109 1.29 ENST00000426126.7
ZDHHC17
zinc finger DHHC-type palmitoyltransferase 17
chr14_-_77377046 1.28 ENST00000216468.8
TMED8
transmembrane p24 trafficking protein family member 8
chr21_-_32727933 1.25 ENST00000357345.7
ENST00000429236.5
SYNJ1
synaptojanin 1
chr2_-_55419565 1.25 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
CCDC88A
coiled-coil domain containing 88A
chr8_-_19013693 1.25 ENST00000327040.13
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_66844914 1.24 ENST00000394069.3
CA7
carbonic anhydrase 7
chr3_+_50674896 1.23 ENST00000266037.10
DOCK3
dedicator of cytokinesis 3
chr12_+_108131740 1.23 ENST00000332082.8
WSCD2
WSC domain containing 2
chr20_+_44247298 1.22 ENST00000342560.10
ENST00000438466.5
ENST00000372952.7
GDAP1L1
ganglioside induced differentiation associated protein 1 like 1
chr12_+_74537787 1.20 ENST00000519948.4
ATXN7L3B
ataxin 7 like 3B
chr1_+_219173861 1.17 ENST00000366927.3
ENST00000366928.10
LYPLAL1
lysophospholipase like 1
chrX_-_120311408 1.14 ENST00000309720.9
TMEM255A
transmembrane protein 255A
chr4_+_169620527 1.14 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
CLCN3
chloride voltage-gated channel 3
chr10_+_1049476 1.13 ENST00000358220.5
WDR37
WD repeat domain 37
chr8_-_118621901 1.13 ENST00000409003.5
ENST00000524796.6
ENST00000314727.9
SAMD12
sterile alpha motif domain containing 12
chr10_+_123666355 1.10 ENST00000284674.2
GPR26
G protein-coupled receptor 26
chr1_+_69568398 1.08 ENST00000310961.9
ENST00000370958.5
LRRC7
leucine rich repeat containing 7
chr13_-_99971739 1.08 ENST00000267294.4
ZIC5
Zic family member 5
chr16_+_81035830 1.08 ENST00000299575.5
ATMIN
ATM interactor
chr9_-_71121596 1.07 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
TRPM3
transient receptor potential cation channel subfamily M member 3
chr9_-_3525968 1.05 ENST00000382004.7
ENST00000617270.5
ENST00000449190.5
RFX3
regulatory factor X3
chr2_+_72917489 1.04 ENST00000258106.11
EMX1
empty spiracles homeobox 1
chr5_-_150113344 1.01 ENST00000286301.7
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr3_+_6861107 1.01 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
GRM7
glutamate metabotropic receptor 7
chr4_-_174829212 1.00 ENST00000340217.5
ENST00000274093.8
GLRA3
glycine receptor alpha 3
chr14_-_74923234 0.99 ENST00000556776.1
ENST00000557413.6
ENST00000555647.5
RPS6KL1
ribosomal protein S6 kinase like 1
chr11_+_35662739 0.98 ENST00000299413.7
TRIM44
tripartite motif containing 44
chr14_-_99272184 0.98 ENST00000357195.8
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr14_-_67695747 0.97 ENST00000553384.5
ENST00000381346.9
ENST00000557726.1
RDH11
retinol dehydrogenase 11
chr3_+_160756225 0.97 ENST00000498165.6
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent 1L
chr2_+_24049673 0.90 ENST00000380991.8
FKBP1B
FKBP prolyl isomerase 1B
chr1_-_240612147 0.90 ENST00000318160.5
GREM2
gremlin 2, DAN family BMP antagonist
chr5_-_61162352 0.89 ENST00000339020.8
ENST00000507416.1
SMIM15
small integral membrane protein 15
chr2_-_68252482 0.89 ENST00000234310.8
PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
chr19_-_48511793 0.89 ENST00000600059.6
LMTK3
lemur tyrosine kinase 3
chr7_-_143362687 0.87 ENST00000409578.5
ENST00000443739.7
ENST00000409346.5
FAM131B
family with sequence similarity 131 member B
chr11_+_46332905 0.86 ENST00000343674.10
DGKZ
diacylglycerol kinase zeta
chr14_-_88792736 0.86 ENST00000554922.5
EML5
EMAP like 5
chr19_+_7830188 0.86 ENST00000270530.8
EVI5L
ecotropic viral integration site 5 like
chr7_+_28412511 0.86 ENST00000357727.7
CREB5
cAMP responsive element binding protein 5
chr7_-_73719629 0.86 ENST00000395155.3
ENST00000395154.7
ENST00000395156.7
ENST00000222812.8
STX1A
syntaxin 1A
chr8_-_95269190 0.85 ENST00000286688.6
C8orf37
chromosome 8 open reading frame 37
chr8_-_91040814 0.83 ENST00000520014.1
ENST00000285419.8
PIP4P2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr17_-_2025289 0.83 ENST00000331238.7
RTN4RL1
reticulon 4 receptor like 1
chr2_+_74654228 0.81 ENST00000611975.4
ENST00000357877.7
ENST00000339773.9
ENST00000434486.5
SEMA4F
ssemaphorin 4F
chr17_+_67377413 0.80 ENST00000580974.5
PITPNC1
phosphatidylinositol transfer protein cytoplasmic 1
chr10_-_86366784 0.80 ENST00000327946.12
GRID1
glutamate ionotropic receptor delta type subunit 1
chr15_+_66386902 0.78 ENST00000307102.10
MAP2K1
mitogen-activated protein kinase kinase 1
chr19_-_14206168 0.74 ENST00000361434.7
ENST00000340736.10
ADGRL1
adhesion G protein-coupled receptor L1
chr3_+_105366877 0.74 ENST00000306107.9
ALCAM
activated leukocyte cell adhesion molecule
chr17_+_15999815 0.73 ENST00000261647.10
TTC19
tetratricopeptide repeat domain 19
chr2_+_158456939 0.72 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
PKP4
plakophilin 4
chr20_+_44401222 0.72 ENST00000316099.9
HNF4A
hepatocyte nuclear factor 4 alpha
chr7_-_113087720 0.71 ENST00000297146.7
GPR85
G protein-coupled receptor 85
chr12_+_10179006 0.69 ENST00000298530.7
TMEM52B
transmembrane protein 52B
chr3_+_10992717 0.65 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
SLC6A1
solute carrier family 6 member 1
chr5_+_181223270 0.65 ENST00000315073.10
ENST00000351937.9
TRIM41
tripartite motif containing 41
chr2_+_190408324 0.65 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chr12_-_94650506 0.64 ENST00000261226.9
TMCC3
transmembrane and coiled-coil domain family 3
chr7_-_103149182 0.62 ENST00000417955.5
ENST00000341533.8
ENST00000425379.1
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D
chr5_-_138875290 0.62 ENST00000521094.2
ENST00000274711.7
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr9_+_126914760 0.61 ENST00000424082.6
ENST00000259351.10
ENST00000394022.7
ENST00000394011.7
ENST00000319107.8
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr9_-_133121228 0.60 ENST00000372050.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr16_+_30065753 0.59 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
ALDOA
aldolase, fructose-bisphosphate A
chr7_-_72336995 0.59 ENST00000329008.9
CALN1
calneuron 1
chr8_-_94896660 0.56 ENST00000520509.5
CCNE2
cyclin E2
chr6_+_20401864 0.55 ENST00000346618.8
ENST00000613242.4
E2F3
E2F transcription factor 3
chr2_-_199457931 0.54 ENST00000417098.6
SATB2
SATB homeobox 2
chr10_-_16521871 0.54 ENST00000298943.4
C1QL3
complement C1q like 3
chr5_+_128083757 0.53 ENST00000262461.7
ENST00000628403.2
ENST00000343225.4
SLC12A2
solute carrier family 12 member 2
chr22_-_29388530 0.53 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
AP1B1
adaptor related protein complex 1 subunit beta 1
chr10_+_43077060 0.53 ENST00000340058.6
ENST00000355710.8
ENST00000498820.5
ENST00000615310.5
RET
ret proto-oncogene
chr3_-_190862688 0.52 ENST00000442080.6
GMNC
geminin coiled-coil domain containing
chr1_-_154870264 0.51 ENST00000618040.4
ENST00000271915.9
KCNN3
potassium calcium-activated channel subfamily N member 3
chr2_+_121755545 0.51 ENST00000536142.5
ENST00000389682.8
TSN
translin
chr14_-_63728027 0.50 ENST00000247225.7
SGPP1
sphingosine-1-phosphate phosphatase 1
chr16_+_66988573 0.49 ENST00000540947.6
ENST00000648724.2
CES4A
carboxylesterase 4A
chr19_-_45792755 0.48 ENST00000377735.7
ENST00000270223.7
DMWD
DM1 locus, WD repeat containing
chr17_-_39197652 0.47 ENST00000394303.8
CACNB1
calcium voltage-gated channel auxiliary subunit beta 1
chr4_+_143336762 0.45 ENST00000262995.8
GAB1
GRB2 associated binding protein 1
chr5_-_95284535 0.44 ENST00000515393.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr9_+_128340474 0.44 ENST00000300456.5
SLC27A4
solute carrier family 27 member 4
chr2_-_201071579 0.42 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
FAM126B
family with sequence similarity 126 member B
chr11_+_61680373 0.42 ENST00000257215.10
DAGLA
diacylglycerol lipase alpha
chr11_-_2885728 0.40 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
CDKN1C
cyclin dependent kinase inhibitor 1C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
2.2 8.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.4 4.2 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
1.4 4.1 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
1.4 8.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.2 3.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.7 3.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.7 2.8 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.7 2.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.6 8.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.6 4.5 GO:0046684 response to pyrethroid(GO:0046684)
0.6 1.7 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.5 1.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.5 1.6 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.5 2.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.5 2.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 2.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 3.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 3.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 2.6 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 3.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 9.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 2.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.3 1.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.3 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.3 1.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 3.9 GO:0015820 leucine transport(GO:0015820)
0.3 2.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 2.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.3 2.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.3 3.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 15.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.1 GO:0072560 type B pancreatic cell maturation(GO:0072560)
0.2 1.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.2 1.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 1.0 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2 4.0 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 2.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 3.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.7 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.2 1.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 2.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 1.4 GO:0015798 myo-inositol transport(GO:0015798)
0.2 2.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 1.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 2.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 2.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 3.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 3.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.8 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 2.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 1.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 3.4 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.9 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 2.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 6.1 GO:0007398 ectoderm development(GO:0007398)
0.1 3.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 1.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 1.7 GO:0098735 relaxation of smooth muscle(GO:0044557) positive regulation of the force of heart contraction(GO:0098735)
0.1 1.3 GO:0097338 response to clozapine(GO:0097338)
0.1 1.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 2.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.1 1.0 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 2.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 6.1 GO:0035640 exploration behavior(GO:0035640)
0.1 0.4 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 6.2 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 0.6 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.1 2.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 1.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0072300 posterior midgut development(GO:0007497) positive regulation of metanephric glomerulus development(GO:0072300) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.4 GO:0021794 thalamus development(GO:0021794)
0.1 2.5 GO:0030575 nuclear body organization(GO:0030575)
0.1 1.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 5.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.2 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.3 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 4.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 3.5 GO:0046710 GDP metabolic process(GO:0046710)
0.1 1.0 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:0034092 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.1 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 2.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 3.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 4.0 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 2.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 5.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 4.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 1.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.3 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0044860 protein localization to plasma membrane raft(GO:0044860) regulation of establishment of T cell polarity(GO:1903903)
0.0 0.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0050651 dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 3.0 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 2.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1903350 response to cisplatin(GO:0072718) response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.8 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 1.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 11.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.5 9.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.9 8.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.8 4.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 4.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.7 2.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.5 8.5 GO:0005883 neurofilament(GO:0005883)
0.3 6.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 2.4 GO:0045298 tubulin complex(GO:0045298)
0.3 4.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 6.2 GO:0033010 paranodal junction(GO:0033010)
0.3 15.3 GO:0033268 node of Ranvier(GO:0033268)
0.3 3.9 GO:0030314 junctional membrane complex(GO:0030314)
0.2 5.0 GO:0031045 dense core granule(GO:0031045)
0.2 3.3 GO:0031209 SCAR complex(GO:0031209)
0.2 1.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 7.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 1.1 GO:0070545 PeBoW complex(GO:0070545)
0.2 3.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 3.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 1.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 2.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 4.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 6.0 GO:0043204 perikaryon(GO:0043204)
0.0 3.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 2.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.6 GO:0043679 axon terminus(GO:0043679)
0.0 2.3 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.0 GO:0098793 presynapse(GO:0098793)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 4.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 3.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.8 8.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 4.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 2.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.5 2.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.5 2.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.5 4.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 2.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 3.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 2.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 20.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 3.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 4.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 2.3 GO:0004771 sterol esterase activity(GO:0004771)
0.3 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 3.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 1.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.3 4.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 4.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 3.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.0 GO:0070905 serine binding(GO:0070905)
0.2 4.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.4 GO:0001515 opioid peptide activity(GO:0001515)
0.2 2.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 3.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 3.9 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 4.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 4.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 2.0 GO:1990239 steroid hormone binding(GO:1990239)
0.1 1.7 GO:0046790 virion binding(GO:0046790)
0.1 2.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 9.9 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 6.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 8.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 6.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 3.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 2.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.0 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 2.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 10.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.8 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 14.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 6.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 3.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 2.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 8.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 5.5 PID REELIN PATHWAY Reelin signaling pathway
0.1 7.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 4.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 19.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 5.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 11.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 11.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 3.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 8.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 3.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis