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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for HIVEP1

Z-value: 0.30

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
ENSG00000095951.17 HIVEP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg38_v1_chr6_+_12012304_120123380.421.6e-02Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_106335613 10.07 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr14_-_106235582 9.12 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr12_-_9760893 8.30 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr14_-_106593319 7.91 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr14_-_106062670 7.88 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr14_-_106360320 7.84 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr14_-_105856183 7.84 ENST00000637539.2
ENST00000390559.6
immunoglobulin heavy constant mu
chr14_-_106675544 7.06 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr14_-_106538331 7.01 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr14_-_106130061 5.53 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr16_+_32066065 5.21 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106154113 4.93 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr14_-_106108453 4.79 ENST00000632950.2
immunoglobulin heavy variable 5-10-1
chr7_-_150800320 4.74 ENST00000492607.5
ENST00000326442.10
ENST00000450753.2
transmembrane protein 176B
chr14_-_106088573 4.71 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr14_-_106411021 4.66 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr14_-_106579223 4.55 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr14_-_106791226 4.32 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr6_+_32439866 3.96 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr6_+_32741382 3.92 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr22_-_37244237 3.85 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr14_-_106211453 3.83 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr22_+_36860973 3.69 ENST00000447071.5
ENST00000397147.7
ENST00000248899.11
neutrophil cytosolic factor 4
chr4_-_108166750 3.51 ENST00000515500.5
lymphoid enhancer binding factor 1
chr6_+_31587268 3.48 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr6_+_29723421 3.47 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr3_-_112133218 3.46 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr6_+_31587185 3.46 ENST00000376092.7
ENST00000376086.7
ENST00000303757.12
ENST00000376093.6
leukocyte specific transcript 1
chr14_-_106811131 3.33 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr17_+_42288464 3.30 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr16_+_33827140 3.27 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr6_-_31357171 3.26 ENST00000412585.7
ENST00000434333.1
major histocompatibility complex, class I, B
chr4_-_108166715 3.22 ENST00000510624.5
lymphoid enhancer binding factor 1
chr14_-_106803221 3.19 ENST00000390636.2
immunoglobulin heavy variable 3-73
chrX_+_47585212 3.18 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr7_-_150800533 3.10 ENST00000434545.5
transmembrane protein 176B
chr4_-_74099187 3.08 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr6_+_29723340 3.06 ENST00000334668.8
major histocompatibility complex, class I, F
chr1_+_37474572 3.05 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr19_-_10334723 3.01 ENST00000592945.1
intercellular adhesion molecule 3
chr6_+_14117764 2.99 ENST00000379153.4
CD83 molecule
chr6_-_31272069 2.99 ENST00000415537.1
ENST00000376228.9
ENST00000383329.7
major histocompatibility complex, class I, C
chr5_-_39219555 2.98 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr4_-_73998669 2.97 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr14_+_75522427 2.95 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr17_+_42288429 2.94 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr9_-_133479075 2.92 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr22_-_37244417 2.88 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr19_-_46625037 2.87 ENST00000596260.1
ENST00000594275.1
ENST00000597185.1
ENST00000598865.5
ENST00000291294.7
prostaglandin I2 receptor
chr12_-_57478070 2.85 ENST00000549602.1
ENST00000430041.6
Rho GTPase activating protein 9
chr8_+_27311471 2.83 ENST00000397501.5
protein tyrosine kinase 2 beta
chr19_-_42132391 2.80 ENST00000528894.8
ENST00000560804.6
ENST00000560558.5
ENST00000560398.5
ENST00000526816.6
ENST00000625670.2
POU class 2 homeobox 2
chr11_+_72814380 2.72 ENST00000534905.5
ENST00000321297.10
ENST00000540567.1
autophagy related 16 like 2
chr16_+_33009175 2.65 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr17_-_19046957 2.64 ENST00000284154.10
ENST00000573099.5
GRB2 related adaptor protein
chr14_-_106470788 2.60 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr14_+_103123452 2.59 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr5_+_136058849 2.56 ENST00000508076.5
transforming growth factor beta induced
chr19_+_14031746 2.53 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr5_-_150412743 2.52 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr12_+_6946468 2.51 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr16_+_32995048 2.49 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr13_-_46182136 2.48 ENST00000323076.7
lymphocyte cytosolic protein 1
chr14_+_51847145 2.45 ENST00000615906.4
G protein subunit gamma 2
chr7_+_150800403 2.45 ENST00000484928.5
transmembrane protein 176A
chr16_+_72054477 2.42 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr9_+_124291935 2.40 ENST00000546191.5
NIMA related kinase 6
chr2_+_218880844 2.39 ENST00000258411.8
Wnt family member 10A
chr3_-_58210961 2.39 ENST00000486455.5
ENST00000394549.7
deoxyribonuclease 1 like 3
chr6_-_32941018 2.37 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr11_-_104968533 2.37 ENST00000444739.7
caspase 4
chr6_+_29942523 2.31 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr14_-_106389858 2.28 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr15_-_78944985 2.23 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr6_-_32668368 2.20 ENST00000399084.5
major histocompatibility complex, class II, DQ beta 1
chr11_+_118883884 2.20 ENST00000292174.5
C-X-C motif chemokine receptor 5
chr11_+_18266254 2.18 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr6_-_73520985 2.17 ENST00000676710.1
ENST00000316292.13
ENST00000309268.11
ENST00000610520.5
ENST00000678515.1
ENST00000678703.1
eukaryotic translation elongation factor 1 alpha 1
chr17_+_19127535 2.15 ENST00000577213.1
ENST00000344415.9
GRB2 related adaptor protein like
chr14_+_75522531 2.10 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr4_-_163332589 2.10 ENST00000296533.3
ENST00000509586.5
ENST00000504391.5
ENST00000512819.1
neuropeptide Y receptor Y1
chr2_+_201183120 2.09 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr7_+_99374240 2.08 ENST00000443222.6
ENST00000414376.5
actin related protein 2/3 complex subunit 1B
chr17_-_28549333 2.06 ENST00000470125.5
unc-119 lipid binding chaperone
chr14_+_22304051 2.05 ENST00000390466.1
T cell receptor alpha variable 39
chr12_-_54973683 2.04 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr10_+_30434021 2.03 ENST00000542547.5
mitogen-activated protein kinase kinase kinase 8
chr6_+_31587049 2.01 ENST00000376089.6
ENST00000396112.6
leukocyte specific transcript 1
chr11_-_75351686 1.99 ENST00000360025.7
arrestin beta 1
chr3_-_58211212 1.99 ENST00000461914.7
deoxyribonuclease 1 like 3
chr6_-_44265541 1.97 ENST00000619360.6
NFKB inhibitor epsilon
chrX_-_30577759 1.96 ENST00000378962.4
TLR adaptor interacting with endolysosomal SLC15A4
chr4_-_108166289 1.95 ENST00000512172.1
lymphoid enhancer binding factor 1
chr4_+_154563003 1.95 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr17_+_7023042 1.93 ENST00000293805.10
BCL6B transcription repressor
chr9_+_90801757 1.92 ENST00000375751.8
ENST00000375754.9
spleen associated tyrosine kinase
chr1_-_169630115 1.92 ENST00000263686.11
ENST00000367788.6
selectin P
chr6_-_73521549 1.91 ENST00000676547.1
eukaryotic translation elongation factor 1 alpha 1
chr19_+_45001430 1.89 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr15_+_90184912 1.89 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr16_+_57358775 1.85 ENST00000219235.5
C-C motif chemokine ligand 22
chr22_+_38957522 1.85 ENST00000618553.1
ENST00000249116.7
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
chr6_-_31736504 1.84 ENST00000616760.1
ENST00000375784.7
ENST00000375779.6
chloride intracellular channel 1
chr12_+_5432101 1.78 ENST00000423158.4
neurotrophin 3
chr11_-_75351609 1.78 ENST00000420843.7
arrestin beta 1
chr2_-_74553934 1.77 ENST00000264094.8
ENST00000393937.6
ENST00000409986.5
lysyl oxidase like 3
chr1_-_169630076 1.74 ENST00000367786.6
ENST00000458599.6
ENST00000367795.2
selectin P
chr16_+_3065297 1.73 ENST00000325568.9
interleukin 32
chr9_-_128724088 1.72 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
zinc finger DHHC-type palmitoyltransferase 12
chr19_-_6591103 1.70 ENST00000423145.7
ENST00000245903.4
CD70 molecule
chr19_-_51630401 1.69 ENST00000683636.1
sialic acid binding Ig like lectin 5
chr14_+_21965451 1.69 ENST00000390442.3
T cell receptor alpha variable 12-3
chr12_-_57478042 1.69 ENST00000548139.5
Rho GTPase activating protein 9
chr4_+_85827891 1.69 ENST00000514229.5
Rho GTPase activating protein 24
chr7_-_22220226 1.66 ENST00000420196.5
Rap guanine nucleotide exchange factor 5
chr6_-_73521783 1.64 ENST00000331523.7
ENST00000356303.7
eukaryotic translation elongation factor 1 alpha 1
chr16_+_56936654 1.61 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr9_+_90801909 1.60 ENST00000375747.5
spleen associated tyrosine kinase
chr7_-_100827504 1.59 ENST00000616502.4
ENST00000358173.8
EPH receptor B4
chr2_+_236569817 1.59 ENST00000272928.4
atypical chemokine receptor 3
chr2_+_73892967 1.58 ENST00000409731.7
ENST00000409918.5
ENST00000442912.5
ENST00000345517.8
ENST00000409624.1
actin gamma 2, smooth muscle
chr10_-_71773513 1.57 ENST00000394957.8
V-set immunoregulatory receptor
chr11_-_105023136 1.55 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr10_+_30434176 1.54 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr1_+_23791962 1.53 ENST00000421070.1
lysophospholipase 2
chr20_+_45891348 1.52 ENST00000419493.3
cathepsin A
chrX_-_101407893 1.50 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr4_+_85827745 1.50 ENST00000509300.5
Rho GTPase activating protein 24
chr1_-_47231715 1.49 ENST00000371884.6
TAL bHLH transcription factor 1, erythroid differentiation factor
chr17_-_64020566 1.47 ENST00000578313.5
ENST00000584084.1
ENST00000579687.5
ENST00000578379.5
ENST00000578892.5
ENST00000579788.6
ENST00000412356.5
ENST00000418105.5
intercellular adhesion molecule 2
chr17_-_1486124 1.46 ENST00000575158.5
myosin IC
chr11_-_57426745 1.45 ENST00000529554.5
solute carrier family 43 member 3
chr4_+_39044995 1.44 ENST00000261425.7
ENST00000508137.6
kelch like family member 5
chr2_-_43226594 1.44 ENST00000282388.4
ZFP36 ring finger protein like 2
chr10_+_30434116 1.43 ENST00000415139.5
mitogen-activated protein kinase kinase kinase 8
chr6_+_33391805 1.43 ENST00000428849.7
ENST00000450504.1
kinesin family member C1
chr6_+_137867241 1.42 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr6_+_32637419 1.41 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr2_+_96816236 1.41 ENST00000377060.7
ENST00000305510.4
cyclin and CBS domain divalent metal cation transport mediator 3
chr1_+_111227699 1.40 ENST00000369748.9
chitinase 3 like 2
chr16_-_11976611 1.40 ENST00000538896.5
ENST00000673243.1
nuclear pore complex interacting protein family member B2
chr17_-_45317006 1.40 ENST00000344686.8
ENST00000617331.3
mitogen-activated protein kinase kinase kinase 14
chr17_-_1485733 1.39 ENST00000648446.1
myosin IC
chr6_+_31587002 1.39 ENST00000376090.6
leukocyte specific transcript 1
chr5_+_50666612 1.39 ENST00000281631.10
poly(ADP-ribose) polymerase family member 8
chr5_-_39424966 1.38 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr19_-_41363930 1.38 ENST00000675972.1
B9 domain containing 2
chr19_+_35000275 1.37 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr12_-_108598036 1.37 ENST00000392806.4
ENST00000547567.1
transmembrane protein 119
chr8_+_24384275 1.36 ENST00000256412.8
ADAM like decysin 1
chr14_+_22320128 1.36 ENST00000390468.1
T cell receptor alpha variable 41
chr17_+_42288076 1.36 ENST00000546010.6
signal transducer and activator of transcription 5A
chr16_-_11587450 1.35 ENST00000571688.5
lipopolysaccharide induced TNF factor
chr12_-_47905003 1.35 ENST00000550325.5
ENST00000546653.5
ENST00000548664.1
vitamin D receptor
chr7_-_98252117 1.35 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr1_+_111227610 1.35 ENST00000369744.6
chitinase 3 like 2
chr19_+_41363989 1.33 ENST00000413014.6
transmembrane protein 91
chr9_+_129665603 1.32 ENST00000372469.6
paired related homeobox 2
chr20_+_45891309 1.32 ENST00000354880.9
ENST00000646241.3
ENST00000191018.9
cathepsin A
chr8_+_27311620 1.32 ENST00000522338.5
protein tyrosine kinase 2 beta
chr12_-_53200443 1.31 ENST00000550743.6
integrin subunit beta 7
chr15_+_49423233 1.29 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr14_+_51847116 1.29 ENST00000553560.5
G protein subunit gamma 2
chr5_+_50666660 1.28 ENST00000515175.6
poly(ADP-ribose) polymerase family member 8
chr12_-_47904986 1.28 ENST00000549336.6
vitamin D receptor
chr22_+_50481515 1.27 ENST00000395737.2
ENST00000395738.2
adrenomedullin 2
chr14_-_95516616 1.26 ENST00000682763.1
spectrin repeat containing nuclear envelope family member 3
chr22_+_39960397 1.26 ENST00000424496.2
novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7
chr17_+_7023062 1.26 ENST00000576705.1
BCL6B transcription repressor
chr9_-_120929160 1.25 ENST00000540010.1
TNF receptor associated factor 1
chr5_-_39424859 1.23 ENST00000503513.5
DAB adaptor protein 2
chr14_+_22086401 1.23 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr1_-_151993822 1.21 ENST00000368811.8
S100 calcium binding protein A10
chr19_+_34994778 1.21 ENST00000599564.5
GRAM domain containing 1A
chr6_+_32637396 1.21 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr2_+_20667136 1.21 ENST00000272224.5
growth differentiation factor 7
chr19_+_926001 1.21 ENST00000263620.8
AT-rich interaction domain 3A
chr20_-_47785439 1.21 ENST00000437955.1
sulfatase 2
chr11_+_59142811 1.21 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr19_-_55258942 1.21 ENST00000412770.7
protein phosphatase 6 regulatory subunit 1
chr8_+_24384455 1.20 ENST00000522298.1
ADAM like decysin 1
chr1_+_113979460 1.19 ENST00000320334.5
olfactomedin like 3
chr1_-_151992571 1.18 ENST00000368809.1
S100 calcium binding protein A10
chr4_-_76023489 1.17 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_+_137867414 1.16 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr12_+_112013348 1.16 ENST00000455836.1
endoplasmic reticulum protein 29
chr20_+_63735463 1.16 ENST00000496820.2
novel protein, ZGPAT-LIME1 readthrough
chr15_+_90868580 1.16 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr19_+_40577158 1.15 ENST00000595631.5
SH3KBP1 binding protein 1
chr1_-_159924529 1.15 ENST00000320307.8
transgelin 2
chr4_-_80073170 1.15 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr17_-_55421818 1.15 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr5_-_139482685 1.14 ENST00000651565.1
stimulator of interferon response cGAMP interactor 1
chr12_+_57230086 1.13 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr11_-_57426638 1.13 ENST00000529112.5
ENST00000529896.1
solute carrier family 43 member 3
chr6_-_27472681 1.11 ENST00000377419.1
zinc finger protein 184
chr12_-_57110284 1.11 ENST00000543873.6
ENST00000554663.5
ENST00000557635.5
signal transducer and activator of transcription 6
chr4_-_80072993 1.11 ENST00000681115.1
ANTXR cell adhesion molecule 2
chr12_+_112013418 1.11 ENST00000261735.4
ENST00000552052.1
endoplasmic reticulum protein 29
chr13_+_30713477 1.11 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.5 15.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.2 8.7 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.0 3.1 GO:2000627 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.9 2.8 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.9 3.5 GO:0002238 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.8 7.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.8 2.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.8 71.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.8 2.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8 10.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.7 4.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.7 2.8 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.7 2.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.6 6.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.6 0.6 GO:2000426 negative regulation of apoptotic cell clearance(GO:2000426)
0.6 5.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.6 2.3 GO:0043335 protein unfolding(GO:0043335)
0.6 2.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.6 1.7 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.5 1.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.5 2.6 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.5 0.5 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.5 2.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.5 3.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.5 2.5 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.5 1.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.5 3.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.5 1.5 GO:0030221 basophil differentiation(GO:0030221)
0.5 1.5 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.5 2.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.4 1.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.4 45.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 3.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 0.7 GO:0046645 positive regulation of gamma-delta T cell activation(GO:0046645)
0.4 3.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 1.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.4 1.8 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.3 1.0 GO:1990051 activation of protein kinase C activity(GO:1990051) regulation of glutamine transport(GO:2000485)
0.3 0.7 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 1.0 GO:0042938 dipeptide transport(GO:0042938)
0.3 3.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.3 1.0 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.3 8.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.3 4.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 1.8 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.2 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.3 3.2 GO:1901164 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.3 5.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.3 3.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.3 1.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 1.6 GO:0070269 pyroptosis(GO:0070269)
0.2 0.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 5.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 2.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.9 GO:0070383 DNA cytosine deamination(GO:0070383)
0.2 2.5 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.2 1.1 GO:0043373 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373)
0.2 1.5 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.2 0.7 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 4.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 2.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.2 3.7 GO:0033623 positive regulation of platelet activation(GO:0010572) regulation of integrin activation(GO:0033623)
0.2 2.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 3.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 3.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 5.7 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 3.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.2 2.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 1.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.0 GO:0030035 microspike assembly(GO:0030035)
0.2 0.9 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 1.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 2.6 GO:0051601 exocyst localization(GO:0051601)
0.2 1.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 2.4 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.2 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1 3.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.9 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 2.3 GO:0032329 serine transport(GO:0032329)
0.1 1.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.6 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)
0.1 1.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.8 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 2.2 GO:0048535 lymph node development(GO:0048535)
0.1 0.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 13.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 3.7 GO:0045730 respiratory burst(GO:0045730)
0.1 0.5 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 2.4 GO:0001765 membrane raft assembly(GO:0001765)
0.1 11.9 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 0.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 1.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 3.1 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 1.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.2 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.1 0.7 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1 3.4 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 0.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 2.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 1.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.3 GO:2000910 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 1.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 2.7 GO:0042092 type 2 immune response(GO:0042092)
0.1 0.3 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 2.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.6 GO:0046070 dGTP metabolic process(GO:0046070)
0.1 2.3 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.9 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.4 GO:0030421 defecation(GO:0030421)
0.1 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 1.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.2 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.1 2.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.4 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 5.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 2.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 1.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 1.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.9 GO:0015816 glycine transport(GO:0015816)
0.0 2.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0061743 motor learning(GO:0061743)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 2.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 3.3 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 1.9 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.5 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.3 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 1.1 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.4 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 1.8 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 1.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.3 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 1.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.6 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 3.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 1.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 2.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 4.1 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) chemokine (C-C motif) ligand 2 secretion(GO:0035926) interleukin-21 secretion(GO:0072619)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.0 1.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
1.4 15.1 GO:0042612 MHC class I protein complex(GO:0042612)
1.2 63.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.9 17.6 GO:0042611 MHC protein complex(GO:0042611)
0.7 3.5 GO:0019814 immunoglobulin complex(GO:0019814)
0.7 2.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.7 3.9 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.6 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 2.9 GO:0045160 myosin I complex(GO:0045160)
0.4 8.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.4 5.3 GO:0070552 BRISC complex(GO:0070552)
0.4 5.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 1.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.3 3.7 GO:0032010 phagolysosome(GO:0032010)
0.3 2.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 2.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 3.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 3.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 1.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.6 GO:1990037 Lewy body core(GO:1990037)
0.2 1.0 GO:0001651 dense fibrillar component(GO:0001651)
0.2 0.8 GO:0043293 apoptosome(GO:0043293)
0.2 1.5 GO:0043196 varicosity(GO:0043196)
0.2 4.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 2.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.0 GO:0044393 microspike(GO:0044393)
0.2 3.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 3.9 GO:0005916 fascia adherens(GO:0005916)
0.2 1.4 GO:0071953 elastic fiber(GO:0071953)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 3.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 3.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.0 GO:0036038 MKS complex(GO:0036038)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.6 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 7.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 4.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 12.6 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 2.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.1 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 19.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 6.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 2.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 3.9 GO:0000922 spindle pole(GO:0000922)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.0 71.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.9 2.6 GO:1902098 calcitriol receptor activity(GO:0008434) lithocholic acid receptor activity(GO:0038186) calcitriol binding(GO:1902098) lithocholic acid binding(GO:1902121)
0.8 4.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.8 6.5 GO:0046979 TAP2 binding(GO:0046979)
0.7 12.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.6 5.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.5 8.7 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 2.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.5 3.7 GO:0042806 fucose binding(GO:0042806)
0.5 2.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 3.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 6.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.4 1.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.3 1.0 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.3 2.4 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 63.6 GO:0003823 antigen binding(GO:0003823)
0.3 1.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.3 3.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 2.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.0 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.2 2.8 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.2 3.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.5 GO:0016936 galactoside binding(GO:0016936)
0.2 3.5 GO:0045159 myosin II binding(GO:0045159)
0.2 5.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 3.2 GO:0004568 chitinase activity(GO:0004568)
0.2 3.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.5 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.2 1.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 3.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2 5.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 3.1 GO:0050700 CARD domain binding(GO:0050700)
0.2 3.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 5.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.6 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 2.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 3.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 2.9 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.4 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 3.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 3.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.6 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.1 2.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 5.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 2.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.1 GO:0001727 lipid kinase activity(GO:0001727)
0.1 3.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 4.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 2.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.4 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 2.0 GO:0017166 vinculin binding(GO:0017166)
0.0 1.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 3.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 2.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 5.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 5.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 6.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.2 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 14.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 10.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 10.2 PID CD40 PATHWAY CD40/CD40L signaling
0.2 5.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 9.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 5.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 2.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 9.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 4.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 7.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 15.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 1.4 REACTOME KINESINS Genes involved in Kinesins
0.3 6.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 2.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 7.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 2.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 8.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.2 8.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 11.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 6.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 4.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 7.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 8.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 3.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 4.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 8.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 5.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 5.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 3.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 3.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs