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avrg: young vs old, Illumina Body Map 2 (GSE30611)
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Results for HOXB7
Z-value: 0.96
Motif logo
Transcription factors associated with HOXB7
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXB7
|
ENSG00000260027.5 | HOXB7 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB7 | hg38_v1_chr17_-_48610971_48611023 | -0.01 | 9.7e-01 | Click! |
Activity profile of HOXB7 motif
Sorted Z-values of HOXB7 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0006147 | guanine catabolic process(GO:0006147) |
| 0.7 | 2.7 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.7 | 2.7 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.6 | 7.6 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.6 | 2.4 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.5 | 3.3 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.4 | 2.2 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.4 | 1.6 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.4 | 2.8 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.4 | 1.6 | GO:0072233 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.4 | 1.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.3 | 4.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.3 | 2.4 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.3 | 6.0 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.3 | 1.3 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.3 | 2.3 | GO:0072221 | metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) |
| 0.3 | 2.0 | GO:1904306 | regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
| 0.2 | 0.7 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.2 | 0.7 | GO:0097272 | ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274) |
| 0.2 | 2.0 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.2 | 0.7 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.2 | 0.8 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.2 | 0.8 | GO:0098942 | cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) |
| 0.2 | 0.6 | GO:0043397 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) |
| 0.2 | 2.0 | GO:0036371 | protein localization to T-tubule(GO:0036371) |
| 0.2 | 0.9 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.2 | 1.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.2 | 0.7 | GO:0048560 | establishment of anatomical structure orientation(GO:0048560) |
| 0.2 | 2.8 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.2 | 0.5 | GO:0033869 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
| 0.2 | 1.2 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 1.2 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 1.0 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 0.9 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.1 | 2.4 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.1 | 0.8 | GO:0071395 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.1 | 1.9 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.1 | 0.4 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) regulation of mRNA modification(GO:0090365) |
| 0.1 | 0.4 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.1 | 1.2 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.1 | 0.8 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) |
| 0.1 | 1.4 | GO:0003172 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.1 | 0.4 | GO:0030186 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 0.1 | 0.6 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.1 | 0.2 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 0.1 | 0.5 | GO:0033306 | phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173) |
| 0.1 | 0.7 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.5 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.1 | 3.3 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
| 0.1 | 0.3 | GO:1903537 | meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.1 | 1.3 | GO:0045915 | positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964) |
| 0.1 | 1.5 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.1 | 1.4 | GO:0015747 | urate transport(GO:0015747) |
| 0.1 | 0.3 | GO:0072198 | intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) kidney smooth muscle tissue development(GO:0072194) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
| 0.1 | 1.4 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 1.8 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.6 | GO:1903251 | multi-ciliated epithelial cell differentiation(GO:1903251) |
| 0.1 | 1.4 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 0.3 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.1 | 0.3 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903) |
| 0.1 | 0.3 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.1 | 0.3 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 1.1 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.1 | 0.6 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 1.7 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.1 | 0.5 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.1 | 0.4 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
| 0.1 | 0.6 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.1 | 1.3 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.1 | 0.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 0.4 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.1 | 1.0 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.1 | 2.7 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.1 | 0.4 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 0.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.5 | GO:0032487 | regulation of Rap protein signal transduction(GO:0032487) |
| 0.1 | 0.7 | GO:0010748 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.1 | 1.1 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 1.0 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.9 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.5 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.1 | 0.4 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.1 | 0.2 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.1 | 1.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 0.2 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.6 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.1 | 0.6 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.1 | 0.4 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.1 | 0.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.9 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.1 | 0.2 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 0.0 | 0.9 | GO:0006559 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.0 | 3.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.7 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.0 | 0.8 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.0 | 0.6 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.0 | 0.7 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.9 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.0 | 0.2 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.0 | 2.6 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 1.5 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.4 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.0 | 1.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.0 | 1.1 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.0 | 2.3 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 1.5 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.0 | 0.3 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.0 | 0.5 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.0 | 0.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 0.0 | 0.2 | GO:0071934 | thiamine transmembrane transport(GO:0071934) |
| 0.0 | 0.4 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 0.0 | 0.3 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.0 | 2.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.4 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.0 | 0.2 | GO:0035513 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.0 | 1.2 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.0 | 0.5 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.4 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.0 | 0.2 | GO:0015811 | sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811) |
| 0.0 | 0.2 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 1.1 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.0 | 1.3 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.4 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.0 | 0.3 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.1 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.0 | 0.2 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.0 | 0.3 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 0.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 1.3 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.0 | 0.3 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.0 | 0.2 | GO:1904220 | regulation of serine C-palmitoyltransferase activity(GO:1904220) |
| 0.0 | 0.3 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 0.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.0 | 1.1 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.0 | 0.4 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.0 | 1.8 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.8 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.2 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.0 | 0.1 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.0 | 1.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 1.9 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.9 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 0.2 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.0 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 6.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.1 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.0 | 0.1 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.0 | 1.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.3 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.3 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.2 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.0 | 0.1 | GO:0035993 | deltoid tuberosity development(GO:0035993) |
| 0.0 | 0.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 4.2 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 1.2 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.0 | 1.6 | GO:0003281 | ventricular septum development(GO:0003281) |
| 0.0 | 0.9 | GO:0014072 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.0 | 0.7 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.0 | 0.3 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.0 | 0.8 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 1.1 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.0 | 0.4 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.8 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.0 | 0.2 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.0 | 0.5 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.2 | GO:0042090 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.0 | 0.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.1 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.0 | 0.5 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.0 | 0.6 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.2 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.0 | 0.1 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 0.4 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.0 | 0.1 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.1 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.4 | GO:0090312 | positive regulation of protein deacetylation(GO:0090312) |
| 0.0 | 1.2 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) |
| 0.0 | 0.0 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.0 | 0.0 | GO:0070121 | pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.3 | 0.9 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.3 | 1.5 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 6.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.9 | GO:0044305 | calyx of Held(GO:0044305) |
| 0.2 | 0.8 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.2 | 0.7 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.2 | 5.1 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 0.5 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.2 | 0.5 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.1 | 1.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.4 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.1 | 1.4 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 2.9 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.3 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.1 | 0.6 | GO:0071942 | XPC complex(GO:0071942) |
| 0.1 | 2.7 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.8 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.1 | 0.8 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 3.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.6 | GO:0098536 | deuterosome(GO:0098536) |
| 0.1 | 0.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.1 | 1.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.1 | 0.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 0.5 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.1 | 1.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 0.8 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 1.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.4 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 0.7 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 3.0 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.5 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.8 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 1.1 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.3 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 0.5 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 2.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 2.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 2.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 2.3 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 2.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 2.4 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 2.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.3 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 1.0 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 2.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.5 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 0.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 1.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.6 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 1.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 2.2 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 1.6 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 2.5 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 0.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 1.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.1 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 1.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.1 | GO:0048500 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 7.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | GO:0008892 | guanine deaminase activity(GO:0008892) |
| 0.5 | 3.8 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.4 | 1.3 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 0.4 | 3.3 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.3 | 1.3 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.3 | 1.6 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.3 | 1.4 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.3 | 1.1 | GO:0051500 | D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500) |
| 0.2 | 2.4 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.2 | 4.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 0.9 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.2 | 8.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 0.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.2 | 2.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.2 | 1.4 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 0.7 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 0.2 | 0.8 | GO:0018636 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) |
| 0.2 | 1.1 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.2 | 3.0 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.2 | 8.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.2 | 0.5 | GO:0019166 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.2 | 0.9 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.1 | 4.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 2.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 0.7 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 0.8 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.1 | 1.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.1 | 0.7 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 1.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 0.6 | GO:0070004 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 0.1 | 0.8 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.1 | 1.5 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 1.4 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 1.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.9 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 0.4 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.1 | 0.3 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 0.1 | 5.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.1 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 0.4 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 0.5 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.1 | 0.5 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 1.0 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.1 | 0.6 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 1.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.5 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 2.4 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 1.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.1 | 0.6 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.1 | 0.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.3 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.1 | 0.3 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.1 | 2.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.6 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.1 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 1.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 0.2 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.1 | 2.3 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.1 | 1.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.3 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) |
| 0.1 | 2.1 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.6 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.1 | 2.2 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 0.9 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.8 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.8 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.0 | 1.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 1.5 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.0 | 0.6 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.0 | 1.2 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 0.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 0.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.4 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 1.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.2 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.0 | 1.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 3.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.8 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 2.2 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.0 | 0.2 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.0 | 0.3 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.0 | 0.6 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.4 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.6 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 1.3 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.0 | 1.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.2 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 1.0 | GO:0071949 | FAD binding(GO:0071949) |
| 0.0 | 0.4 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.3 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.0 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.7 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 1.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.0 | 0.1 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.0 | 1.0 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.7 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 0.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.1 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.0 | 0.1 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.0 | 0.4 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.0 | 0.3 | GO:0008934 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.0 | 6.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.3 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.0 | 1.9 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.4 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.0 | 2.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.4 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.1 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.0 | 0.9 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.2 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 0.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 1.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.3 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.1 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.0 | 0.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.7 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 0.6 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 0.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.4 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.7 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 0.1 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.0 | 1.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.1 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 0.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 4.3 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 4.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 1.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.8 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.9 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.2 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 1.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.7 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.8 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 0.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 7.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.7 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 2.2 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 3.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 3.6 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 3.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 5.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.0 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 0.9 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 1.4 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.6 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 1.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 0.8 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 2.2 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.1 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.0 | 1.3 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 2.0 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 3.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.7 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.0 | 0.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 1.7 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 1.2 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 0.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 2.9 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.0 | 0.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.3 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 5.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.2 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.9 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 1.8 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.2 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.7 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.8 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 1.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 2.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 4.6 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.4 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.2 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.6 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 0.4 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.8 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.3 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 2.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |