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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for HSF2

Z-value: 0.40

Motif logo

Transcription factors associated with HSF2

Gene Symbol Gene ID Gene Info
ENSG00000025156.13 HSF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF2hg38_v1_chr6_+_122399536_1223995680.421.8e-02Click!

Activity profile of HSF2 motif

Sorted Z-values of HSF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_128830399 6.23 ENST00000325888.13
ENST00000346177.6
filamin C
chr8_+_133113483 3.45 ENST00000521107.1
thyroglobulin
chr15_+_78264086 3.20 ENST00000394855.7
ENST00000489435.2
DnaJ heat shock protein family (Hsp40) member A4
chr11_-_111910830 3.19 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr11_-_111910888 3.12 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr7_+_76302665 2.99 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr1_-_168729187 2.93 ENST00000367817.4
dermatopontin
chr5_-_147453888 2.92 ENST00000398514.7
dihydropyrimidinase like 3
chrX_+_136197020 2.86 ENST00000370676.7
four and a half LIM domains 1
chr11_-_111910790 2.85 ENST00000533280.6
crystallin alpha B
chrX_+_136197039 2.77 ENST00000370683.6
four and a half LIM domains 1
chrX_+_136148440 2.75 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr12_+_119178920 2.73 ENST00000281938.7
heat shock protein family B (small) member 8
chr12_+_119178953 2.60 ENST00000674542.1
heat shock protein family B (small) member 8
chr2_-_216695540 2.60 ENST00000233813.5
insulin like growth factor binding protein 5
chrX_+_136196750 2.60 ENST00000539015.5
four and a half LIM domains 1
chr6_+_31815532 2.58 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr6_+_31827730 2.47 ENST00000375650.5
heat shock protein family A (Hsp70) member 1B
chr4_+_76011171 2.41 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chr6_-_123636979 2.31 ENST00000662930.1
triadin
chr10_+_122211175 2.01 ENST00000496913.6
transforming acidic coiled-coil containing protein 2
chr9_-_34710069 2.00 ENST00000378792.1
ENST00000259607.7
C-C motif chemokine ligand 21
chr15_+_78264552 1.97 ENST00000394852.8
ENST00000343789.7
DnaJ heat shock protein family (Hsp40) member A4
chr6_-_31815244 1.94 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like
chr6_-_123636923 1.93 ENST00000334268.9
triadin
chr7_-_80919017 1.93 ENST00000265361.8
semaphorin 3C
chr5_+_80035341 1.91 ENST00000350881.6
thrombospondin 4
chr11_+_12674397 1.85 ENST00000527636.7
TEA domain transcription factor 1
chr7_+_30921430 1.76 ENST00000409899.5
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr16_+_71358713 1.73 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr6_-_123636997 1.70 ENST00000546248.5
triadin
chr19_-_14518383 1.62 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr18_+_34593312 1.53 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr12_+_2794961 1.53 ENST00000001008.6
FKBP prolyl isomerase 4
chr6_+_151325665 1.52 ENST00000354675.10
A-kinase anchoring protein 12
chr4_+_76011222 1.49 ENST00000513122.5
ADP-ribosyltransferase 3 (inactive)
chrX_-_103686687 1.46 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
mortality factor 4 like 2
chr15_+_42359577 1.46 ENST00000357568.8
calpain 3
chr16_+_176659 1.34 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr2_-_187554351 1.33 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr3_+_96814552 1.33 ENST00000470610.6
ENST00000389672.9
EPH receptor A6
chr11_-_90223059 1.32 ENST00000457199.6
ENST00000530765.5
cysteine and histidine rich domain containing 1
chr4_-_185956348 1.27 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr6_-_109094819 1.25 ENST00000436639.6
sestrin 1
chr3_+_45026296 1.23 ENST00000296130.5
C-type lectin domain family 3 member B
chr14_-_25010604 1.23 ENST00000550887.5
syntaxin binding protein 6
chr7_+_157336988 1.21 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DnaJ heat shock protein family (Hsp40) member B6
chr11_-_90223036 1.21 ENST00000320585.11
cysteine and histidine rich domain containing 1
chr4_-_107036302 1.18 ENST00000285311.8
dickkopf WNT signaling pathway inhibitor 2
chr14_-_52069228 1.14 ENST00000617139.4
nidogen 2
chrX_+_103773709 1.08 ENST00000434483.5
proteolipid protein 1
chr9_+_34989641 1.06 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr13_-_31161927 1.06 ENST00000380405.7
heat shock protein family H (Hsp110) member 1
chr3_+_159069252 1.05 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr18_-_812230 1.05 ENST00000314574.5
YES proto-oncogene 1, Src family tyrosine kinase
chr3_-_112641292 1.03 ENST00000439685.6
coiled-coil domain containing 80
chr1_-_36450410 1.02 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr14_-_52069039 1.01 ENST00000216286.10
nidogen 2
chr1_-_184037695 0.98 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chr13_-_31161890 0.97 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr6_-_123636906 0.97 ENST00000628709.2
triadin
chr11_-_65557740 0.94 ENST00000526927.5
latent transforming growth factor beta binding protein 3
chr9_+_841691 0.89 ENST00000382276.8
doublesex and mab-3 related transcription factor 1
chr13_-_31162341 0.89 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chr7_+_157336961 0.87 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr11_+_102047422 0.86 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr17_-_41505597 0.86 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr3_-_64687992 0.85 ENST00000498707.5
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr11_+_72080803 0.84 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr20_+_46118300 0.84 ENST00000372285.8
ENST00000372276.7
CD40 molecule
chr20_+_46118277 0.80 ENST00000620709.4
CD40 molecule
chr14_-_23155302 0.80 ENST00000529705.6
solute carrier family 7 member 8
chr2_-_187554473 0.79 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr15_-_58065703 0.79 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr3_+_96814791 0.75 ENST00000506569.1
EPH receptor A6
chr14_+_88594406 0.74 ENST00000555900.5
zinc finger CCCH-type containing 14
chr6_+_152697934 0.70 ENST00000532295.1
MYC target 1
chr11_+_27040826 0.70 ENST00000533566.5
gamma-butyrobetaine hydroxylase 1
chr11_+_75562274 0.70 ENST00000532356.5
ENST00000524558.5
serpin family H member 1
chr1_-_205994439 0.69 ENST00000617991.4
RAB7B, member RAS oncogene family
chr9_+_89311187 0.69 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr3_+_133124807 0.69 ENST00000508711.5
transmembrane protein 108
chr3_-_64687982 0.68 ENST00000459780.1
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr2_-_178672418 0.67 ENST00000448510.2
titin
chr15_+_96325935 0.67 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr14_+_88594430 0.67 ENST00000406216.7
ENST00000557737.1
zinc finger CCCH-type containing 14
chr6_+_152697888 0.66 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr11_+_66509079 0.65 ENST00000419755.3
novel protein
chr20_+_58852710 0.64 ENST00000676826.2
ENST00000371100.9
GNAS complex locus
chr3_-_123692347 0.62 ENST00000508240.1
myosin light chain kinase
chr3_-_112641128 0.62 ENST00000206423.8
coiled-coil domain containing 80
chr4_-_185956652 0.62 ENST00000355634.9
sorbin and SH3 domain containing 2
chr1_+_192575765 0.62 ENST00000469578.2
ENST00000367459.8
regulator of G protein signaling 1
chr2_-_197499857 0.62 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr7_+_157337043 0.61 ENST00000437030.5
DnaJ heat shock protein family (Hsp40) member B6
chr11_+_75562056 0.61 ENST00000533603.5
serpin family H member 1
chr17_-_62806632 0.61 ENST00000583803.1
ENST00000456609.6
membrane associated ring-CH-type finger 10
chr11_+_27040725 0.61 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr9_+_125748175 0.58 ENST00000491787.7
ENST00000447726.6
PBX homeobox 3
chr11_+_72080595 0.58 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr6_-_32154326 0.58 ENST00000475826.1
ENST00000485392.5
ENST00000494332.5
ENST00000498575.1
ENST00000428778.5
novel transcript
novel protein
chr1_-_36450279 0.56 ENST00000445843.7
organic solute carrier partner 1
chr3_+_156037693 0.56 ENST00000472028.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr2_-_197499826 0.55 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr6_+_44247866 0.55 ENST00000371554.2
heat shock protein 90 alpha family class B member 1
chr2_-_74343397 0.55 ENST00000394019.6
ENST00000377634.8
ENST00000436454.1
solute carrier family 4 member 5
chr14_-_102087034 0.54 ENST00000216281.13
ENST00000553585.5
heat shock protein 90 alpha family class A member 1
chr5_+_140125935 0.54 ENST00000333305.5
IgA inducing protein
chr9_+_125747345 0.53 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX homeobox 3
chr6_-_123636966 0.53 ENST00000542443.5
triadin
chr17_-_76141240 0.52 ENST00000322957.7
forkhead box J1
chr11_-_72080472 0.52 ENST00000537217.5
ENST00000366394.7
ENST00000358965.10
ENST00000546131.1
ENST00000393695.8
ENST00000543937.5
ENST00000368959.9
ENST00000541641.5
nuclear mitotic apparatus protein 1
chr4_-_163473732 0.52 ENST00000280605.5
transketolase like 2
chr19_-_48746797 0.51 ENST00000602105.1
ENST00000332955.7
izumo sperm-egg fusion 1
chr20_+_18813777 0.51 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr12_+_106684696 0.48 ENST00000229387.6
regulatory factor X4
chr4_+_76435216 0.47 ENST00000296043.7
shroom family member 3
chr9_-_89178810 0.47 ENST00000375835.9
SHC adaptor protein 3
chr2_+_197500371 0.46 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr4_-_158723355 0.46 ENST00000307720.4
peptidylprolyl isomerase D
chr9_-_34589716 0.45 ENST00000378980.8
ciliary neurotrophic factor receptor
chr14_+_88594395 0.44 ENST00000318308.10
zinc finger CCCH-type containing 14
chrX_-_103688033 0.44 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr11_-_72080680 0.44 ENST00000613205.4
nuclear mitotic apparatus protein 1
chrX_-_119606412 0.44 ENST00000304449.8
NFKB repressing factor
chr1_-_119648165 0.43 ENST00000421812.3
zinc finger protein 697
chr13_+_23570370 0.42 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr11_-_133956957 0.42 ENST00000533871.8
immunoglobulin superfamily member 9B
chr8_-_26513865 0.42 ENST00000522362.7
PNMA family member 2
chr9_-_34589701 0.41 ENST00000351266.8
ciliary neurotrophic factor receptor
chr19_+_47257520 0.41 ENST00000599398.5
ENST00000595659.5
coiled-coil domain containing 9
chr16_+_715092 0.41 ENST00000568223.7
meteorin, glial cell differentiation regulator
chr5_-_160312524 0.41 ENST00000520748.1
ENST00000257536.13
ENST00000393977.7
cyclin J like
chr4_-_22515932 0.41 ENST00000502482.1
adhesion G protein-coupled receptor A3
chr20_+_31547367 0.41 ENST00000394552.3
MCTS family member 2, pseudogene
chrX_-_103688090 0.40 ENST00000433176.6
mortality factor 4 like 2
chr12_+_69585434 0.40 ENST00000299300.11
ENST00000544368.6
chaperonin containing TCP1 subunit 2
chr20_+_4686320 0.39 ENST00000430350.2
prion protein
chr17_-_58417521 0.39 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr18_+_24139013 0.39 ENST00000399481.6
ENST00000327201.10
calcium binding tyrosine phosphorylation regulated
chr11_+_75562134 0.38 ENST00000526242.1
serpin family H member 1
chr2_-_218286763 0.37 ENST00000444881.5
transmembrane BAX inhibitor motif containing 1
chrX_-_154371210 0.36 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr8_+_109540075 0.36 ENST00000614147.1
ENST00000337573.10
estrogen receptor binding site associated antigen 9
chr1_+_26921715 0.35 ENST00000321265.10
nuclear distribution C, dynein complex regulator
chr14_-_77423517 0.34 ENST00000555603.1
NADP dependent oxidoreductase domain containing 1
chr9_-_13279407 0.33 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr5_-_160312756 0.33 ENST00000644313.1
cyclin J like
chr4_-_76421121 0.33 ENST00000682701.1
coiled-coil domain containing 158
chr8_+_86866415 0.33 ENST00000518476.6
cyclic nucleotide binding domain containing 1
chr2_-_177263522 0.33 ENST00000448782.5
ENST00000446151.6
nuclear factor, erythroid 2 like 2
chr7_-_150955796 0.32 ENST00000330883.9
potassium voltage-gated channel subfamily H member 2
chr6_+_149218631 0.30 ENST00000606202.1
ENST00000445901.1
TGF-beta activated kinase 1 (MAP3K7) binding protein 2
novel transcript
chr14_+_32494227 0.30 ENST00000554410.5
A-kinase anchoring protein 6
chr11_+_12674555 0.29 ENST00000527376.3
TEA domain transcription factor 1
chr7_-_42152396 0.29 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr7_+_130344810 0.28 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr7_-_83649097 0.28 ENST00000643230.2
semaphorin 3E
chr12_-_122526929 0.26 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
arginine and serine rich coiled-coil 2
chr21_+_43728851 0.26 ENST00000327574.4
pyridoxal kinase
chr12_+_57745017 0.26 ENST00000547992.5
ENST00000552816.5
ENST00000257910.8
ENST00000547472.5
tetraspanin 31
chr18_+_46917561 0.26 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr8_-_119592954 0.26 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr16_-_1444489 0.26 ENST00000389176.3
ENST00000409671.5
coiled-coil domain containing 154
chr6_-_135054785 0.24 ENST00000367820.6
ENST00000314674.7
ENST00000524715.5
ENST00000415177.6
ENST00000367826.6
ENST00000367837.10
HBS1 like translational GTPase
chr17_-_58417547 0.24 ENST00000577716.5
ring finger protein 43
chr15_+_67542668 0.23 ENST00000178640.10
mitogen-activated protein kinase kinase 5
chrX_-_139222777 0.23 ENST00000448673.1
fibroblast growth factor 13
chr7_+_23598144 0.23 ENST00000410069.1
coiled-coil domain containing 126
chr11_+_86302211 0.22 ENST00000533986.5
ENST00000278483.8
heat shock protein nuclear import factor hikeshi
chr10_-_99913971 0.22 ENST00000543621.6
dynamin binding protein
chr11_+_1834415 0.22 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr13_+_45702306 0.22 ENST00000533564.1
ENST00000310521.6
chibby family member 2
chr11_-_123062335 0.19 ENST00000453788.6
ENST00000527387.5
heat shock protein family A (Hsp70) member 8
chr11_+_46295126 0.18 ENST00000534787.1
cAMP responsive element binding protein 3 like 1
chr18_+_3451647 0.18 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr8_-_140921188 0.18 ENST00000517887.5
protein tyrosine kinase 2
chr18_-_46917432 0.18 ENST00000324794.11
ENST00000545673.5
ENST00000585916.6
protein inhibitor of activated STAT 2
chr11_+_66002754 0.18 ENST00000527348.1
BAF nuclear assembly factor 1
chr11_-_83285965 0.18 ENST00000529073.5
ENST00000529611.5
coiled-coil domain containing 90B
chr7_+_130344837 0.17 ENST00000485477.5
ENST00000431780.6
carboxypeptidase A5
chr18_-_25224689 0.17 ENST00000577775.1
zinc finger protein 521
chr2_-_96740034 0.17 ENST00000264963.9
ENST00000377079.8
lectin, mannose binding 2 like
chr11_+_1834804 0.16 ENST00000341958.3
synaptotagmin 8
chr11_-_124310837 0.16 ENST00000357821.2
olfactory receptor family 8 subfamily D member 1
chr17_-_78577383 0.16 ENST00000389840.7
dynein axonemal heavy chain 17
chr3_-_184017863 0.16 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr2_-_177263418 0.15 ENST00000423513.5
nuclear factor, erythroid 2 like 2
chr8_-_80171496 0.15 ENST00000379096.9
ENST00000518937.6
tumor protein D52
chr12_+_69585666 0.14 ENST00000543146.2
chaperonin containing TCP1 subunit 2
chr15_-_43493105 0.14 ENST00000382039.7
ENST00000450115.6
ENST00000382044.9
tumor protein p53 binding protein 1
chr1_+_151198536 0.13 ENST00000349792.9
ENST00000409426.5
ENST00000368888.9
ENST00000441902.6
ENST00000368890.8
ENST00000424999.1
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chr6_-_155314444 0.13 ENST00000367166.5
transcription factor B1, mitochondrial
chr13_+_45702411 0.13 ENST00000610924.1
chibby family member 2
chr4_-_185956327 0.13 ENST00000444781.5
ENST00000432655.5
sorbin and SH3 domain containing 2
chr2_-_10837977 0.13 ENST00000404824.2
protein disulfide isomerase family A member 6
chr10_+_119726118 0.12 ENST00000369081.3
ENST00000648262.1
inositol polyphosphate-5-phosphatase F
chr14_+_37622065 0.12 ENST00000553443.5
tetratricopeptide repeat domain 6
chr5_-_160312476 0.11 ENST00000519673.1
cyclin J like
chr1_+_11778931 0.11 ENST00000444493.5
chromosome 1 open reading frame 167

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
1.3 5.1 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.9 2.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.7 2.0 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.6 2.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6 1.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.5 3.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.4 2.9 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.4 9.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 9.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 1.2 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.4 1.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 3.5 GO:0015705 iodide transport(GO:0015705)
0.2 1.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 1.6 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.2 0.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 2.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.9 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.6 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 1.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 1.5 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 1.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.7 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 1.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 12.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.3 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.1 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 1.0 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.8 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.6 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 2.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 3.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.2 GO:0051601 exocyst localization(GO:0051601)
0.1 0.9 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 1.4 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 2.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.5 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.5 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409) glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.3 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.4 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.1 2.1 GO:0042026 protein refolding(GO:0042026)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 5.7 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.8 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 1.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 2.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 5.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 2.2 GO:0071711 basement membrane organization(GO:0071711)
0.0 1.3 GO:0015671 oxygen transport(GO:0015671)
0.0 2.1 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0022018 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 1.1 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 1.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.5 9.2 GO:0097512 cardiac myofibril(GO:0097512)
0.5 7.4 GO:0033018 junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
0.4 2.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.6 GO:0043196 varicosity(GO:0043196)
0.2 0.6 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.2 1.2 GO:0001652 granular component(GO:0001652)
0.2 0.9 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 2.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 3.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0097229 sperm end piece(GO:0097229)
0.1 1.0 GO:0055028 cortical microtubule(GO:0055028)
0.1 6.2 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 5.1 GO:0016235 aggresome(GO:0016235)
0.1 1.2 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.0 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 2.9 GO:0031941 filamentous actin(GO:0031941)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 6.8 GO:0030018 Z disc(GO:0030018)
0.0 6.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 13.0 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 4.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.6 1.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.5 5.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 3.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 1.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 9.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 1.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.6 GO:0002135 CTP binding(GO:0002135)
0.2 1.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 6.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.4 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 4.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 2.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.5 GO:0031432 titin binding(GO:0031432)
0.1 0.9 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 11.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 20.1 GO:0044325 ion channel binding(GO:0044325)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 2.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0052810 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 5.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 5.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 2.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC