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avrg: young vs old, Illumina Body Map 2 (GSE30611)

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Results for NANOG

Z-value: 0.95

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Transcription factors associated with NANOG

Gene Symbol Gene ID Gene Info
NANOG
ENSG00000111704.11 NANOG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NANOGhg38_v1_chr12_+_7789393_77894170.077.1e-01Click!

Activity profile of NANOG motif

Sorted Z-values of NANOG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NANOG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_36090133 2.83 ENST00000613922.2
CCL3
C-C motif chemokine ligand 3
chr5_+_157266079 2.76 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_67437670 2.04 ENST00000326294.4
PTPRCAP
protein tyrosine phosphatase receptor type C associated protein
chrX_-_119693370 1.98 ENST00000360156.11
ENST00000354228.8
ENST00000489216.5
ENST00000354416.7
ENST00000343984.5
SEPTIN6
septin 6
chr3_-_56775506 1.67 ENST00000497267.5
ARHGEF3
Rho guanine nucleotide exchange factor 3
chr17_+_29043124 1.57 ENST00000323372.9
PIPOX
pipecolic acid and sarcosine oxidase
chr22_+_26169474 1.56 ENST00000404234.7
ENST00000529632.6
ENST00000360929.7
ENST00000629590.2
ENST00000343706.8
SEZ6L
seizure related 6 homolog like
chr7_-_78771265 1.55 ENST00000630991.2
ENST00000629359.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_170816562 1.53 ENST00000625689.2
ENST00000375272.5
GAD1
glutamate decarboxylase 1
chr5_+_157266148 1.52 ENST00000611075.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr13_+_108269629 1.45 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr5_-_116536458 1.43 ENST00000510263.5
SEMA6A
semaphorin 6A
chr6_+_155216637 1.38 ENST00000275246.11
TIAM2
TIAM Rac1 associated GEF 2
chr1_-_28193873 1.37 ENST00000305392.3
ENST00000539896.1
PTAFR
platelet activating factor receptor
chr10_+_62374361 1.37 ENST00000395254.8
ZNF365
zinc finger protein 365
chr7_-_78771058 1.36 ENST00000628781.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_46124046 1.36 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr6_-_32192630 1.33 ENST00000375040.8
GPSM3
G protein signaling modulator 3
chrX_-_119693150 1.33 ENST00000394610.7
SEPTIN6
septin 6
chr10_+_128047559 1.31 ENST00000306042.9
PTPRE
protein tyrosine phosphatase receptor type E
chr6_-_161274010 1.29 ENST00000366911.9
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr7_-_78771108 1.28 ENST00000626691.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_165327659 1.28 ENST00000507013.5
ENST00000261507.11
ENST00000393766.6
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr22_-_30266839 1.27 ENST00000403463.1
ENST00000215781.3
OSM
oncostatin M
chr11_-_57237183 1.26 ENST00000606794.1
APLNR
apelin receptor
chr5_-_116536428 1.26 ENST00000515009.5
SEMA6A
semaphorin 6A
chr8_-_27611325 1.23 ENST00000523500.5
CLU
clusterin
chr7_+_142352802 1.21 ENST00000634605.1
TRBV7-2
T cell receptor beta variable 7-2
chrX_+_104112511 1.20 ENST00000537356.3
ENST00000650639.1
ZCCHC18
zinc finger CCHC-type containing 18
chr1_+_159302321 1.20 ENST00000368114.1
FCER1A
Fc fragment of IgE receptor Ia
chr11_-_35360050 1.18 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr8_-_27611424 1.17 ENST00000405140.7
CLU
clusterin
chr3_-_98522514 1.17 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr22_+_37051731 1.16 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
KCTD17
potassium channel tetramerization domain containing 17
chr7_-_78770859 1.16 ENST00000636717.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_-_42302766 1.15 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr17_+_77376083 1.13 ENST00000427674.6
SEPTIN9
septin 9
chr3_-_98522754 1.11 ENST00000513287.5
ENST00000514537.5
ENST00000508071.1
ENST00000507944.5
CLDND1
claudin domain containing 1
chr22_+_26169454 1.10 ENST00000248933.11
SEZ6L
seizure related 6 homolog like
chr7_-_26995237 1.10 ENST00000432747.1
SKAP2
src kinase associated phosphoprotein 2
chr12_-_89708816 1.10 ENST00000428670.8
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr11_-_84923162 1.09 ENST00000524982.5
DLG2
discs large MAGUK scaffold protein 2
chr16_+_68539213 1.08 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90
ZFP90 zinc finger protein
chr1_-_202160577 1.08 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr6_-_161274042 1.06 ENST00000320285.9
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_-_155990062 1.04 ENST00000462460.6
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr8_-_27611200 1.03 ENST00000520796.5
ENST00000520491.5
CLU
clusterin
chr8_-_27611866 0.98 ENST00000519742.5
CLU
clusterin
chr8_-_27611679 0.98 ENST00000560566.5
CLU
clusterin
chr20_-_21514046 0.97 ENST00000377142.5
NKX2-2
NK2 homeobox 2
chr10_+_10798570 0.96 ENST00000638035.1
ENST00000636488.1
CELF2
CUGBP Elav-like family member 2
chr22_+_41699492 0.96 ENST00000401548.8
ENST00000540833.1
MEI1
meiotic double-stranded break formation protein 1
chrX_-_19747574 0.96 ENST00000432234.5
SH3KBP1
SH3 domain containing kinase binding protein 1
chr14_+_22052503 0.95 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr12_-_122716790 0.95 ENST00000528880.3
HCAR3
hydroxycarboxylic acid receptor 3
chr10_+_62374175 0.91 ENST00000395255.7
ENST00000647733.1
ZNF365
ENSG00000285837.1
zinc finger protein 365
novel protein
chr1_-_202159977 0.90 ENST00000367279.8
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr3_+_122055355 0.90 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr11_-_84923403 0.89 ENST00000532653.5
DLG2
discs large MAGUK scaffold protein 2
chr2_-_96870752 0.88 ENST00000449330.1
SEMA4C
semaphorin 4C
chr19_-_42302576 0.87 ENST00000262890.8
PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr5_-_95284535 0.87 ENST00000515393.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr10_+_70815889 0.87 ENST00000373202.8
SGPL1
sphingosine-1-phosphate lyase 1
chr7_+_150685693 0.81 ENST00000223293.10
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr8_-_90082871 0.81 ENST00000265431.7
CALB1
calbindin 1
chr6_+_30557274 0.80 ENST00000376557.3
PRR3
proline rich 3
chr6_-_119078642 0.80 ENST00000621231.4
ENST00000338891.12
FAM184A
family with sequence similarity 184 member A
chr19_-_36379185 0.79 ENST00000270001.12
ZFP14
ZFP14 zinc finger protein
chr7_+_142492121 0.78 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6
chrX_-_134797134 0.77 ENST00000370790.5
ENST00000493333.5
ENST00000611027.2
ENST00000343004.10
ENST00000298090.10
PABIR2
PABIR family member 2
chr12_-_57016517 0.77 ENST00000441881.5
ENST00000458521.7
TAC3
tachykinin precursor 3
chr16_+_68539737 0.77 ENST00000398253.6
ENST00000573161.1
ZFP90
ZFP90 zinc finger protein
chr13_+_108269880 0.76 ENST00000542136.1
TNFSF13B
TNF superfamily member 13b
chr19_-_53824288 0.75 ENST00000324134.11
ENST00000391773.6
ENST00000391775.7
ENST00000345770.9
ENST00000391772.1
NLRP12
NLR family pyrin domain containing 12
chr1_+_203128279 0.74 ENST00000367235.1
ENST00000618295.1
ADORA1
adenosine A1 receptor
chr19_-_13102848 0.74 ENST00000264824.5
LYL1
LYL1 basic helix-loop-helix family member
chr4_+_56216101 0.74 ENST00000504228.6
CRACD
capping protein inhibiting regulator of actin dynamics
chr4_+_153152163 0.73 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
TRIM2
ENSG00000288637.1
tripartite motif containing 2
novel protein
chr6_-_24719146 0.73 ENST00000378119.9
C6orf62
chromosome 6 open reading frame 62
chr5_-_170389349 0.72 ENST00000274629.9
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr1_+_161581339 0.72 ENST00000543859.5
ENST00000611236.1
FCGR2C
Fc fragment of IgG receptor IIc (gene/pseudogene)
chr11_-_72793592 0.71 ENST00000536377.5
ENST00000359373.9
STARD10
ARAP1
StAR related lipid transfer domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr6_+_30557287 0.67 ENST00000376560.8
PRR3
proline rich 3
chr22_+_37051787 0.67 ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr19_-_42302292 0.66 ENST00000594989.5
PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr4_-_13627647 0.65 ENST00000040738.10
BOD1L1
biorientation of chromosomes in cell division 1 like 1
chr9_+_109780179 0.64 ENST00000314527.9
PALM2AKAP2
PALM2 and AKAP2 fusion
chr12_-_84912783 0.64 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
SLC6A15
solute carrier family 6 member 15
chr18_-_49487216 0.63 ENST00000318240.8
ENST00000613385.4
C18orf32
chromosome 18 open reading frame 32
chr12_-_84912816 0.63 ENST00000680469.1
ENST00000450363.4
ENST00000681106.1
SLC6A15
solute carrier family 6 member 15
chr12_-_53507482 0.61 ENST00000267017.4
ENST00000448979.4
NPFF
neuropeptide FF-amide peptide precursor
chr12_+_118981531 0.60 ENST00000267260.5
SRRM4
serine/arginine repetitive matrix 4
chr1_+_44405247 0.60 ENST00000361799.7
ENST00000372247.6
RNF220
ring finger protein 220
chr17_+_7484357 0.60 ENST00000674977.2
POLR2A
RNA polymerase II subunit A
chr19_-_42302690 0.59 ENST00000596265.5
PAFAH1B3
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr12_+_57434778 0.58 ENST00000309668.3
INHBC
inhibin subunit beta C
chr10_+_96129707 0.58 ENST00000316045.9
ZNF518A
zinc finger protein 518A
chr6_+_31572279 0.58 ENST00000418386.3
LTA
lymphotoxin alpha
chr1_+_44405164 0.57 ENST00000355387.6
RNF220
ring finger protein 220
chr1_+_62436297 0.57 ENST00000452143.5
ENST00000442679.5
ENST00000371146.5
USP1
ubiquitin specific peptidase 1
chr12_-_122703346 0.55 ENST00000328880.6
HCAR2
hydroxycarboxylic acid receptor 2
chr10_+_96130027 0.54 ENST00000478086.5
ENST00000624776.3
ZNF518A
zinc finger protein 518A
chr15_+_44288701 0.53 ENST00000299957.11
ENST00000559222.5
ENST00000650436.1
GOLM2
golgi membrane protein 2
chr7_-_77199808 0.52 ENST00000248598.6
FGL2
fibrinogen like 2
chrX_+_86148441 0.52 ENST00000373125.9
ENST00000373131.5
DACH2
dachshund family transcription factor 2
chr3_+_15427551 0.50 ENST00000396842.7
EAF1
ELL associated factor 1
chr15_+_44288757 0.50 ENST00000345795.6
GOLM2
golgi membrane protein 2
chr6_+_155216959 0.49 ENST00000462408.2
TIAM2
TIAM Rac1 associated GEF 2
chr12_-_24902243 0.48 ENST00000538118.5
BCAT1
branched chain amino acid transaminase 1
chr12_+_119989869 0.48 ENST00000397558.6
BICDL1
BICD family like cargo adaptor 1
chr19_+_7069679 0.48 ENST00000252840.11
ENST00000414706.2
ZNF557
zinc finger protein 557
chrX_-_48971829 0.46 ENST00000218176.4
KCND1
potassium voltage-gated channel subfamily D member 1
chr2_+_45651650 0.45 ENST00000306156.8
PRKCE
protein kinase C epsilon
chr4_+_153153023 0.44 ENST00000676458.1
ENST00000675782.1
TRIM2
tripartite motif containing 2
chr1_+_27392612 0.43 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr3_-_15427497 0.42 ENST00000443029.5
ENST00000383789.9
ENST00000450816.6
ENST00000383790.8
METTL6
methyltransferase like 6
chr18_-_26091175 0.42 ENST00000579061.5
ENST00000542420.6
SS18
SS18 subunit of BAF chromatin remodeling complex
chr16_+_30748378 0.42 ENST00000563588.6
ENST00000328273.11
PHKG2
phosphorylase kinase catalytic subunit gamma 2
chr7_+_98211431 0.41 ENST00000609256.2
BHLHA15
basic helix-loop-helix family member a15
chr6_+_31571957 0.41 ENST00000454783.5
LTA
lymphotoxin alpha
chr18_-_26090584 0.41 ENST00000415083.7
SS18
SS18 subunit of BAF chromatin remodeling complex
chr12_-_51083582 0.40 ENST00000548206.1
ENST00000546935.5
ENST00000228515.6
ENST00000548981.5
CSRNP2
cysteine and serine rich nuclear protein 2
chr3_-_49813880 0.39 ENST00000333486.4
UBA7
ubiquitin like modifier activating enzyme 7
chr3_+_75906666 0.38 ENST00000487694.7
ENST00000602589.5
ROBO2
roundabout guidance receptor 2
chr1_+_40983148 0.37 ENST00000372616.1
CTPS1
CTP synthase 1
chr3_+_38346760 0.36 ENST00000427323.5
ENST00000207870.8
ENST00000650590.1
XYLB
xylulokinase
chr6_+_30717433 0.36 ENST00000681435.1
TUBB
tubulin beta class I
chr12_-_42484298 0.36 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
PRICKLE1
prickle planar cell polarity protein 1
chr14_+_23322019 0.36 ENST00000557702.5
PABPN1
poly(A) binding protein nuclear 1
chr10_-_71737824 0.36 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr6_-_136289824 0.36 ENST00000527536.5
ENST00000529826.5
ENST00000531224.6
ENST00000353331.8
ENST00000628517.2
BCLAF1
BCL2 associated transcription factor 1
chr12_+_53954870 0.35 ENST00000243103.4
HOXC12
homeobox C12
chr21_-_33588624 0.35 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DONSON
DNA replication fork stabilization factor DONSON
chr3_-_120742506 0.35 ENST00000273375.8
ENST00000483733.1
RABL3
RAB, member of RAS oncogene family like 3
chr6_-_130956371 0.34 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr19_-_13103151 0.33 ENST00000590974.1
LYL1
LYL1 basic helix-loop-helix family member
chr16_+_30748241 0.33 ENST00000565924.5
ENST00000424889.7
PHKG2
phosphorylase kinase catalytic subunit gamma 2
chr10_+_8045345 0.32 ENST00000643001.1
GATA3
GATA binding protein 3
chr3_+_44874606 0.32 ENST00000296125.9
TGM4
transglutaminase 4
chr12_-_121793668 0.31 ENST00000267205.7
RHOF
ras homolog family member F, filopodia associated
chr19_-_39435910 0.31 ENST00000599539.5
RPS16
ribosomal protein S16
chr4_-_107283746 0.31 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr2_+_48314637 0.29 ENST00000413569.5
ENST00000340553.8
FOXN2
forkhead box N2
chr8_-_142777174 0.29 ENST00000652477.1
ENST00000614491.1
ENST00000613110.4
LYNX1
Ly6/neurotoxin 1
chr6_-_136289778 0.29 ENST00000530767.5
ENST00000527759.5
BCLAF1
BCL2 associated transcription factor 1
chr1_-_115841116 0.29 ENST00000320238.3
NHLH2
nescient helix-loop-helix 2
chr14_+_23321543 0.29 ENST00000556821.5
PABPN1
poly(A) binding protein nuclear 1
chr2_-_213151590 0.27 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr10_-_68332914 0.27 ENST00000358769.7
ENST00000495025.2
PBLD
phenazine biosynthesis like protein domain containing
chr6_-_20212403 0.27 ENST00000324607.8
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr1_-_47190013 0.26 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr1_-_150268941 0.25 ENST00000369109.8
ENST00000236017.5
APH1A
aph-1 homolog A, gamma-secretase subunit
chr14_+_20688756 0.25 ENST00000397990.5
ENST00000555597.1
ANG
RNASE4
angiogenin
ribonuclease A family member 4
chr5_-_170389634 0.25 ENST00000521859.1
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr17_-_45051575 0.25 ENST00000588499.5
ENST00000593094.1
ENST00000651974.1
DCAKD
dephospho-CoA kinase domain containing
chr3_+_129249594 0.24 ENST00000314797.10
COPG1
COPI coat complex subunit gamma 1
chr19_-_38852321 0.24 ENST00000600873.5
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr10_+_128047406 0.24 ENST00000467366.1
PTPRE
protein tyrosine phosphatase receptor type E
chr4_-_107283689 0.24 ENST00000513208.5
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr15_+_77420957 0.24 ENST00000559099.5
HMG20A
high mobility group 20A
chr5_-_55994945 0.23 ENST00000381298.7
ENST00000502326.7
IL6ST
interleukin 6 signal transducer
chr4_+_39698156 0.23 ENST00000503368.5
ENST00000445950.2
UBE2K
ubiquitin conjugating enzyme E2 K
chrX_+_14529516 0.23 ENST00000218075.9
GLRA2
glycine receptor alpha 2
chr4_+_39698109 0.22 ENST00000510934.5
ENST00000261427.10
UBE2K
ubiquitin conjugating enzyme E2 K
chr14_-_56805648 0.22 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
OTX2
orthodenticle homeobox 2
chr19_+_926001 0.22 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr7_+_142455120 0.21 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4
chr9_-_123268538 0.21 ENST00000360998.3
ENST00000348403.10
STRBP
spermatid perinuclear RNA binding protein
chr16_+_28974764 0.20 ENST00000565975.5
ENST00000311008.16
ENST00000323081.12
ENST00000334536.12
SPNS1
sphingolipid transporter 1 (putative)
chr22_-_41688859 0.19 ENST00000401959.6
ENST00000648674.1
SNU13
small nuclear ribonucleoprotein 13
chr11_+_26332117 0.18 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr19_-_39435627 0.18 ENST00000599705.1
RPS16
ribosomal protein S16
chr17_-_45051517 0.18 ENST00000614054.4
DCAKD
dephospho-CoA kinase domain containing
chr15_+_41256907 0.18 ENST00000560965.1
CHP1
calcineurin like EF-hand protein 1
chr1_-_145859043 0.18 ENST00000369298.5
PIAS3
protein inhibitor of activated STAT 3
chr6_+_87322581 0.18 ENST00000608353.5
ENST00000392863.6
ENST00000229570.9
ENST00000608525.5
ENST00000608868.2
SMIM8
small integral membrane protein 8
chr7_+_48924559 0.17 ENST00000650262.1
CDC14C
cell division cycle 14C
chr1_-_145859061 0.17 ENST00000393045.7
PIAS3
protein inhibitor of activated STAT 3
chr11_+_34051722 0.17 ENST00000341394.9
ENST00000389645.7
CAPRIN1
cell cycle associated protein 1
chr17_-_75270999 0.17 ENST00000579194.6
ENST00000580717.5
ENST00000577542.5
ENST00000579612.5
ENST00000245551.9
ENST00000578305.5
MIF4GD
MIF4G domain containing
chr15_+_78540405 0.17 ENST00000560217.5
ENST00000559082.5
ENST00000559948.5
ENST00000413382.6
ENST00000559146.5
ENST00000044462.12
ENST00000558281.5
PSMA4
proteasome 20S subunit alpha 4
chr19_-_39435936 0.17 ENST00000339471.8
ENST00000601655.5
ENST00000251453.8
RPS16
ribosomal protein S16
chr6_+_151239951 0.17 ENST00000402676.7
AKAP12
A-kinase anchoring protein 12
chr10_-_48605032 0.16 ENST00000249601.9
ARHGAP22
Rho GTPase activating protein 22
chr6_+_26087281 0.15 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
HFE
homeostatic iron regulator
chr1_+_161663147 0.15 ENST00000236937.13
ENST00000367961.8
ENST00000358671.9
FCGR2B
Fc fragment of IgG receptor IIb
chr6_+_106629560 0.15 ENST00000369046.8
QRSL1
glutaminyl-tRNA amidotransferase subunit QRSL1
chr6_+_116529013 0.15 ENST00000628083.1
ENST00000368597.6
ENST00000452373.5
ENST00000405399.5
CALHM4
calcium homeostasis modulator family member 4
chr4_+_88592426 0.15 ENST00000431413.5
ENST00000402738.6
ENST00000422770.5
ENST00000407637.5
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr10_-_68332878 0.15 ENST00000309049.8
PBLD
phenazine biosynthesis like protein domain containing
chr20_-_3781440 0.15 ENST00000379756.3
SPEF1
sperm flagellar 1
chr6_-_30717437 0.14 ENST00000425072.5
MDC1
mediator of DNA damage checkpoint 1
chr19_+_41310148 0.13 ENST00000269967.4
CCDC97
coiled-coil domain containing 97
chr7_-_144259722 0.13 ENST00000493325.1
OR2A7
olfactory receptor family 2 subfamily A member 7
chr17_-_75270710 0.13 ENST00000581777.2
MIF4GD
MIF4G domain containing
chr20_-_62926469 0.11 ENST00000354665.8
ENST00000370368.5
ENST00000395340.5
ENST00000395343.6
DIDO1
death inducer-obliterator 1
chr8_+_28701487 0.11 ENST00000220562.9
EXTL3
exostosin like glycosyltransferase 3
chr18_+_13218769 0.11 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chrX_+_103918872 0.10 ENST00000419165.5
TMSB15B
thymosin beta 15B
chr17_+_7573722 0.10 ENST00000581384.5
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.4 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 2.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.5 2.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.2 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 1.0 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.3 0.7 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.3 4.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 1.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3 0.9 GO:0002668 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 5.4 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.3 1.4 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.3 1.6 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2 0.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 1.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.2 1.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.5 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 0.2 GO:0016068 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.6 GO:0070253 somatostatin secretion(GO:0070253)
0.1 1.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.4 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.8 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.7 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 1.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.3 GO:0015820 leucine transport(GO:0015820)
0.1 0.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.8 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 2.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 2.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:2000701 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 2.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.4 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 1.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 1.1 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.8 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 1.0 GO:0090220 meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 2.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 5.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.5 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.0 2.2 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.7 3.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 5.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 1.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.2 1.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 5.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.5 GO:0035276 ethanol binding(GO:0035276)
0.1 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.7 GO:0019864 IgG binding(GO:0019864)
0.1 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0070975 FHA domain binding(GO:0070975)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 3.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 5.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 4.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 4.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 5.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling